[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

WO2017087912A3 - Ratiometric biosensors and non-geometrically modulated fret - Google Patents

Ratiometric biosensors and non-geometrically modulated fret Download PDF

Info

Publication number
WO2017087912A3
WO2017087912A3 PCT/US2016/062958 US2016062958W WO2017087912A3 WO 2017087912 A3 WO2017087912 A3 WO 2017087912A3 US 2016062958 W US2016062958 W US 2016062958W WO 2017087912 A3 WO2017087912 A3 WO 2017087912A3
Authority
WO
WIPO (PCT)
Prior art keywords
biosensors
ratiometric
fret
geometrically modulated
ratiometric biosensors
Prior art date
Application number
PCT/US2016/062958
Other languages
French (fr)
Other versions
WO2017087912A2 (en
Inventor
Homme W. Hellinga
Malin J. Allert
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Priority to EP16867307.7A priority Critical patent/EP3377610A4/en
Priority to CA3005883A priority patent/CA3005883A1/en
Publication of WO2017087912A2 publication Critical patent/WO2017087912A2/en
Publication of WO2017087912A3 publication Critical patent/WO2017087912A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Optical Transform (AREA)

Abstract

The present subject matter provides ratiometric biosensors as well as compositions, devices, and methods comprising such biosensors.
PCT/US2016/062958 2015-11-20 2016-11-19 Ratiometric biosensors and non-geometrically modulated fret WO2017087912A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP16867307.7A EP3377610A4 (en) 2015-11-20 2016-11-19 RATIOMETRIC BIOSENSORS AND NON-MODULATED GEOMETRICALLY MODIFIED FÖRSTER RESONANCE ENERGY TRANSFER
CA3005883A CA3005883A1 (en) 2015-11-20 2016-11-19 Ratiometric biosensors and non-geometrically modulated fret

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562257859P 2015-11-20 2015-11-20
US201562257850P 2015-11-20 2015-11-20
US201562257796P 2015-11-20 2015-11-20
US201562257863P 2015-11-20 2015-11-20
US62/257,850 2015-11-20
US62/257,863 2015-11-20
US62/257,859 2015-11-20
US62/257,796 2015-11-20

Publications (2)

Publication Number Publication Date
WO2017087912A2 WO2017087912A2 (en) 2017-05-26
WO2017087912A3 true WO2017087912A3 (en) 2017-07-06

Family

ID=58719234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2016/062958 WO2017087912A2 (en) 2015-11-20 2016-11-19 Ratiometric biosensors and non-geometrically modulated fret

Country Status (3)

Country Link
EP (1) EP3377610A4 (en)
CA (1) CA3005883A1 (en)
WO (1) WO2017087912A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
WO2017087915A1 (en) 2015-11-20 2017-05-26 Duke University Lactate biosensors and uses thereof
WO2017087914A2 (en) 2015-11-20 2017-05-26 Duke University Urea biosensors and uses thereof
WO2017087916A2 (en) 2015-11-20 2017-05-26 Duke University Thermostable glucose biosensors and uses thereof
EP3538665B1 (en) 2016-11-14 2024-01-03 PPB Technology Pty Ltd Protease sensor molecules
US11667900B2 (en) 2017-07-14 2023-06-06 The Regents Of The University Of California Compositions and methods for enhancing macrophage-mediated antibody guided cancer cell or tumor eradication
US11662349B2 (en) * 2017-08-08 2023-05-30 Commonwealth Scientific And Industrial Research Organisation Carbohydrate sensors
CN110596072B (en) * 2019-10-29 2022-05-13 陕西师范大学 Ratio-type fluorescent paper chip based on polyester fiber film, preparation method and application
KR20240032892A (en) 2021-07-01 2024-03-12 나노템퍼 테크놀로지스 게엠베하 Method and device for ratiometric characterization of fluorescent particles
WO2023107545A1 (en) * 2021-12-07 2023-06-15 Chemtreat, Inc. Fluorescence detection of sulfite in water treatment applications

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020004217A1 (en) * 1997-12-31 2002-01-10 Duke University Biosensor
US6432723B1 (en) * 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes
US20020142347A1 (en) * 2000-11-10 2002-10-03 Biosensor Aps Biosensor
US20030186229A1 (en) * 1996-01-31 2003-10-02 Tsien Roger Y. Emission ratiometric indicators of phosphorylation
US20060004271A1 (en) * 2004-07-01 2006-01-05 Peyser Thomas A Devices, methods, and kits for non-invasive glucose measurement
US20110117590A1 (en) * 2007-02-08 2011-05-19 Hillson Nathan J Heavy Metal Biosensor
US20120028265A1 (en) * 2007-08-10 2012-02-02 Thijs Kaper Methods of using ret nanosensors
US20140243223A1 (en) * 2008-09-23 2014-08-28 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186229A1 (en) * 1996-01-31 2003-10-02 Tsien Roger Y. Emission ratiometric indicators of phosphorylation
US20020004217A1 (en) * 1997-12-31 2002-01-10 Duke University Biosensor
US6432723B1 (en) * 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes
US20020142347A1 (en) * 2000-11-10 2002-10-03 Biosensor Aps Biosensor
US20060004271A1 (en) * 2004-07-01 2006-01-05 Peyser Thomas A Devices, methods, and kits for non-invasive glucose measurement
US20110117590A1 (en) * 2007-02-08 2011-05-19 Hillson Nathan J Heavy Metal Biosensor
US20120028265A1 (en) * 2007-08-10 2012-02-02 Thijs Kaper Methods of using ret nanosensors
US20140243223A1 (en) * 2008-09-23 2014-08-28 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HELM, P.: "Proposal of a New Method for Measuring Forster Resonance Energy Transfer (FRET) Rapidly, Quantitatively and Non-Destructively", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 13, 26 September 2012 (2012-09-26), pages 12367 - 12382, XP 055396116 *
RAIMONDO ET AL.: "A genetically-encoded chloride and pH sensor for dissociating ion dynamics in the nervous system", FRONTIERSINCELLULARNEUROSCIENCE, vol. 7, 13 November 2013 (2013-11-13), pages 1 - 10, XP055543195, DOI: 10.3389/fncel.2013.00202 *
See also references of EP3377610A4 *

Also Published As

Publication number Publication date
EP3377610A4 (en) 2019-10-16
WO2017087912A2 (en) 2017-05-26
EP3377610A2 (en) 2018-09-26
CA3005883A1 (en) 2017-05-26

Similar Documents

Publication Publication Date Title
WO2017087912A3 (en) Ratiometric biosensors and non-geometrically modulated fret
WO2016073789A3 (en) Anti-fgfr2/3 antibodies and methods using same
EP3665156A4 (en) Compounds, compositions and methods
WO2017178653A3 (en) NEW ANTI-SIRPa ANTIBODIES AND THEIR THERAPEUTIC APPLICATIONS
WO2018006074A3 (en) Compounds and methods for modulating rna function
WO2016044463A3 (en) Mk2 inhibitors and uses thereof
WO2018109170A3 (en) Il-11ra antibodies
WO2018097666A3 (en) Ionic compound, and coating composition and organic light-emitting device comprising same
WO2016077381A8 (en) Anti-interleukin-33 antibodies and uses thereof
WO2018109174A3 (en) Il-11 antibodies
SG10201803042PA (en) Anti-tim-3 antibodies
WO2016171406A3 (en) Organic light-emitting device
EP3750907A3 (en) Raav-based compositions and methods for treating amyotrophic lateral sclerosis
WO2017077085A3 (en) Immunomodulatory antibodies
WO2015168643A3 (en) Compositions and methods related to engineered fc constructs
WO2017087916A3 (en) Thermostable glucose biosensors and uses thereof
EP4112611A3 (en) Modulators of sestrin-gator2 interaction and uses thereof
WO2015082046A3 (en) Substituted oxepines
WO2016205531A3 (en) Anti-her2 antibodies and methods of use
WO2016061389A3 (en) Anti-alpha-synuclein antibodies and methods of use
WO2016060996A3 (en) Interleukin-15 compositions and uses thereof
WO2015168019A3 (en) Anti-ptk7 antibody-drug conjugates
WO2015191951A3 (en) Modulation of complement activity
WO2019123015A8 (en) Lysophosphatidylcholine compositions
WO2015179658A3 (en) Anti-gpc3 antibodies and immunoconjugates

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16867307

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 3005883

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2016867307

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2016867307

Country of ref document: EP

Effective date: 20180620

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16867307

Country of ref document: EP

Kind code of ref document: A2