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WO2014126189A1 - X-ray imaging device and x-ray imaging method - Google Patents

X-ray imaging device and x-ray imaging method Download PDF

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Publication number
WO2014126189A1
WO2014126189A1 PCT/JP2014/053436 JP2014053436W WO2014126189A1 WO 2014126189 A1 WO2014126189 A1 WO 2014126189A1 JP 2014053436 W JP2014053436 W JP 2014053436W WO 2014126189 A1 WO2014126189 A1 WO 2014126189A1
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WO
WIPO (PCT)
Prior art keywords
ray
energy
pixel
detector
imaging
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PCT/JP2014/053436
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French (fr)
Japanese (ja)
Inventor
浩一 尾川
明敏 勝又
勉 山河
政廣 辻田
Original Assignee
株式会社テレシステムズ
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Priority to JP2015500304A priority Critical patent/JPWO2014126189A1/en
Publication of WO2014126189A1 publication Critical patent/WO2014126189A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/501Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the head, e.g. neuroimaging or craniography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computed tomography [CT]
    • A61B6/032Transmission computed tomography [CT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/44Constructional features of apparatus for radiation diagnosis
    • A61B6/4405Constructional features of apparatus for radiation diagnosis the apparatus being movable or portable, e.g. handheld or mounted on a trolley
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/51Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for dentistry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/17Circuit arrangements not adapted to a particular type of detector
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/29Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
    • G01T1/2914Measurement of spatial distribution of radiation
    • G01T1/2985In depth localisation, e.g. using positron emitters; Tomographic imaging (longitudinal and transverse section imaging; apparatus for radiation diagnosis sequentially in different planes, steroscopic radiation diagnosis)

Definitions

  • the present invention relates to an X-ray imaging apparatus that irradiates a desired imaging region of an object, detects radiation transmitted through the object, and identifies a tissue constituting the imaging region based on the detection data, In particular, tissue identification of an imaging region based on X-ray absorption data corresponding to the number of X-ray photons (photons) in each of a plurality of X-ray energy bands detected by a photon counting (photon counting) type detector,
  • the present invention relates to an X-ray imaging apparatus and an X-ray imaging method that provide functions such as data collection of shape data and imaging of tomographic images.
  • a detector for detecting radiation is indispensable for this type of apparatus, and the improvement of the performance of this radiation detector plays a part in the above-mentioned technological progress.
  • so-called digitization in which detection signals are output in a digital format, is becoming increasingly finer and the detection surface is becoming larger.
  • a detection method called a photon counting method is also attracting attention.
  • This photon counting method has been conventionally used in gamma ray detectors in the field of nuclear medicine (see, for example, Patent Document 1).
  • Patent Document 1 On the other hand, in recent years, there have been reports of cases in which this photon counting method is applied to an X-ray detector in order to obtain effects such as enhancement of image enhancement capability, reduction of metal artifacts, and reduction of the effects of beam hardening.
  • Patent Document 2 The one proposed in Patent Document 2 is known as one example of this type.
  • the photon counting type detector that outputs the electric signal corresponding to the energy of the particle by regarding the radiation incident on each of the plurality of pixels as a photon is provided. Based on this, the count value of the number of photons of the radiation classified into a plurality of energy regions on the energy spectrum of the radiation is calculated, and the calculated count value of each of the plurality of energy regions for each pixel is given for each energy region.
  • the radiation detection apparatus that performs weighting of the weighting factors, adds the count values of the plurality of weighted energy regions for each pixel, and outputs the added data as radiation image generation data for each pixel.
  • one or more (preferably a plurality of) thresholds for discriminating the energy of each incident X-ray photon are prepared. Since the energy range is defined by this threshold value, it is possible to determine to which energy range the energy of each X-ray photon belongs. As a result of this determination, the number of X-ray photons discriminated into the respective energy ranges is counted. This count value information is reflected as the pixel value of the image.
  • an X-ray tube for supplying separate tube voltages and two detectors each paired with these X-ray tubes are mounted. Therefore, the substance is identified using the difference in X-ray energy detected by the two detectors.
  • the number of X-ray tube / detector pairs is not necessarily plural, and a pair of X-ray tubes and detectors may be used.
  • the tube voltage supplied to the X-ray tube is switched between two at high speed at a speed faster than the acquisition speed, and two types of images collected under the two tube voltages are separated and extracted. Substance identification can also be performed.
  • the CT scanner is a device for obtaining a so-called CT value.
  • the CT value differs if the type of substance is different, and even if the substance is the same, the CT value will differ if the X-ray energy (tube voltage) applied is different. It is to try.
  • the present invention has been made in view of the above circumstances, and is detected by a photon counting type detector in an X-ray imaging apparatus having a dental CT scanner function for imaging an imaging target such as a subject's jaw.
  • an X-ray imaging apparatus capable of accurately and simply executing CT reconstruction processing for identifying (or identifying and identifying) the type of substance existing in an imaging target using the projection data for each energy region. That is the purpose.
  • an X-ray imaging apparatus includes two X-ray tubes that emit white X-rays and two pixels that output an electric pulse corresponding to incident X-ray photons.
  • a detection circuit having a dimensionally arranged pixel group and N or more energy thresholds (N ⁇ 4) are given to the continuous energy of the X-ray, and the N electric pulses output from each pixel are given.
  • the number of photons of the X-rays is divided into the N energy thresholds divided by the N energy thresholds and between the N energy thresholds.
  • a photon counting detector having a collecting means for collecting each pixel, the X-ray tube and the detector face each other, and at the time of CT imaging, the X-ray tube and the detector
  • a support that is rotatably supported around Means, scanning means for rotating the X-ray tube and the detector around the object to be imaged based on the instructed scanning method at the time of the CT imaging, and at least one of the “N ⁇ 1” energy bands
  • the projection data based on the number of photons of the X-rays collected by the collecting means is subjected to reconstruction processing for CT (computed tomography), and each of the at least two energy bands.
  • Reconstructing means for reconstructing a CT image Reconstructing means for reconstructing a CT image.
  • a detection circuit having an X-ray tube that emits white X-rays, and a pixel group in which pixels that output electric pulses corresponding to incident X-ray photons are two-dimensionally arranged;
  • a photon counting detector having a collecting means for collecting the number of photons of the X-ray for each pixel, the X-ray tube and the detector facing each other, and at the time of CT imaging, the X-ray tube and the detection
  • a support unit that rotatably supports the imaging device around the imaging target, and a scanning unit that rotates the X-ray tube and the detector around the imaging target based on the instructed scanning method during the CT imaging,
  • An X-ray imaging method is provided in an X-ray imaging apparatus comprising: In this X-ray imaging method, the CT imaging is performed in a state where N energy thresholds (N ⁇ 3) or more are given to the acquisition means with respect to the continuous energy of the X-ray, and the CT image output from each pixel is output.
  • An electric pulse is discriminated by the N energy thresholds by the collecting means, and the number of photons of the X-ray is divided by the N energy thresholds and “N ⁇ ” between the N energy thresholds.
  • the X-rays collected for each pixel in accordance with each of the “1” energy bands, and collected by the collecting means for each of at least two energy bands of the “N ⁇ 1” energy bands.
  • the projection data based on the number of photons is subjected to reconstruction processing for CT (computed tomography) to reconstruct CT images of the at least two energy bands.
  • identifying (identifying, identifying) a substance means identifying the type of substance present in an imaging target such as a subject's jaw from a CT image obtained by reconstructing projection data. It is a concept that includes knowing the thickness (relative and absolute thickness) of the target substance. This material identification is called X-ray transmission information based on a count value obtained by capturing X-rays as particles, that is, photons, and counting the X-ray photons for each energy region, and beam hardening exhibited by the X-ray particles. And information on curing of wire quality.
  • Beam hardening is a phenomenon in which the high energy component of X-rays is relatively larger than the low energy component, and generally uses the expression that the quality of the wire becomes harder (wire quality hardening phenomenon).
  • This phenomenon of linear hardening usually becomes stronger (larger) as the thickness of the substance is larger and the density of the substance is higher.
  • transmission information there are many cases in which there is a difference in the radiation hardening phenomenon.
  • the apparatus includes a substance identification unit that identifies the type of substance that forms the imaging target based on pixel values of the image of each of the at least two energy bands reconstructed by the reconstruction unit. It is.
  • the substance identifying means is a quantity based on a sum of pixel values of the image of all the at least two energy bands, and a relative attenuation index for each pixel representing a relative attenuation with respect to a reference substance, and the at least 2 Two or more dimensions including a pixel quality change index for each pixel based on a division between a pixel value of the image in the higher energy band of the energy bands and a pixel value of the image in the lower energy band It is desirable to provide a scatter diagram creating means for creating a scatter diagram having the following dimensions.
  • the highest threshold value among the N energy threshold values is set to a desired upper limit value of the energy value of the X-ray photon.
  • the number of X-ray photons is “N ⁇ 1” (N ⁇ 3) using a photon counting detector. It counts for every pixel according to each energy band.
  • Reconstruction processing for CT is performed on projection data based on the counted number of photons of X-rays for each of at least two energy bands among the “N ⁇ 1” energy bands. . Thereby, the image of each of the at least two energy bands is reconstructed.
  • CT image data reflecting the number of X-ray photons obtained in this energy band can be used to create a scatter diagram having two or more dimensions including, for example, a relative attenuation index and a quality change index.
  • this scatter diagram shows the scatter characteristics according to various substances included in the imaging target, the substance can be identified using this scatter diagram. Therefore, the type of substance to be imaged can be identified (identified and discriminated) more accurately and easily than various conventional substance identification methods.
  • FIG. 1 is a perspective view of an X-ray hybrid machine having a CT imaging function according to an embodiment.
  • FIG. 2 is a diagram for explaining the arrangement of the X-ray tube and the detector of the X-ray hybrid machine
  • FIG. 3 is another view for explaining the arrangement of the X-ray tube and the detector of the X-ray hybrid machine together with the rotatable directions of the X-ray tube and the detector and their facing states.
  • FIG. 4 is a diagram of an arrangement example illustrating the outline of the configuration of the detector
  • FIG. 5 is a block diagram illustrating the electrical configuration of the detector.
  • FIG. 6 is a graph for explaining the relationship between an electrical pulse detected in response to the incidence of X-ray photons and a threshold value, which is given to a photon counting detector.
  • FIG. 7 is a graph for explaining an example of the relationship between the energy spectrum with respect to the incidence frequency (count value) of X-ray photons and the energy region given by the discrimination circuit;
  • FIG. 8 is a block diagram showing an outline of the electrical configuration of the entire X-ray hybrid machine,
  • FIG. 9 is a flowchart for explaining the flow of substance identification processing executed in the embodiment;
  • FIG. 10 is a schematic diagram illustrating the relationship between the energy region and the reconstruction process for each region.
  • FIG. 11 is a graph showing dimensions of a scatter diagram adopted in the embodiment.
  • FIG. 12 is a graph schematically showing an example of a scatter diagram created by the substance identification process of the embodiment;
  • FIG. 13 is a graph schematically showing how the types of substances in the jaw are identified on the scatter diagram.
  • FIG. 14 is a graph illustrating the advantage of discriminating two substances using a two-dimensional scatter diagram.
  • FIG. 15 is another graph illustrating the advantages of discriminating two substances using a two-dimensional scatter diagram.
  • FIG. 16 is a circuit diagram showing a modification of the detector.
  • This X-ray CT apparatus is configured as a dental X-ray hybrid machine that also has an X-ray panoramic imaging function that captures a panoramic image of a subject's jaw (including a dentition) as an imaging target.
  • this single dental X-ray hybrid machine has one piece of hardware, but the operator selects the type of software from “panoramic photography” and “CT photography” so that the same hardware can be used. Both imaging can be selectively performed using the wear.
  • a pseudo three-dimensional cross-sectional image of the jaw of the subject (the image itself is a two-dimensional image, but is displayed in a three-dimensional manner according to the shape of the imaging part such as a dentition) Can be taken).
  • CT imaging a CT image of the jaw of the subject can be obtained. Both functions use an X-ray tube and an X-ray detector (hereinafter simply referred to as a detector) that go around the jaw of the subject. X-rays emitted from the X-ray tube pass through the jaw and are detected by a detector.
  • this detector captures X-rays (actually, X-ray beams formed into a fan shape or a cone shape by a slit (aperture)) as a bundle of photons (particles), and the photons It is a photon counting (photon counting) type detector that obtains counting information according to the number of the photons. For this reason, the X-ray transmission data transmitted through the jaw reflects the number of photons.
  • the fan-shaped X-ray beam is used for panoramic imaging, and the cone-shaped X-ray beam is used for CT imaging.
  • this dental X-ray hybrid machine is configured to operate to generate image data of a desired or specified cross section of the jaw under the tomosynthesis method when obtaining a “panoramic image”. Yes. Thereby, panoramic image data of the cross section is created. Since this panoramic photography itself is known, the description thereof is simplified or omitted in the present embodiment.
  • the X-ray hybrid machine which concerns on this embodiment is demonstrated as a dental imaging device, the use of this X-ray hybrid machine is not necessarily restricted to dentistry. As other imaging applications, it can be applied to imaging various parts such as mammography, otolaryngology, bones and joints of limbs. It can also be applied to uses such as corpse identification for identity identification and nondestructive inspection.
  • FIG. 1 shows an appearance of a dental X-ray hybrid machine 1 according to this embodiment.
  • the dental X-ray hybrid machine 1 includes a pedestal 12 on which a caster 11 is mounted, an elevating unit 13 and a power supply box 14 mounted on the pedestal 12, and a console 17.
  • the elevating unit 13 includes an elevating mechanism (not shown) therein, and the upper elevating unit of the unit is configured to be movable up and down within a predetermined range electrically with respect to the base 12 (that is, the floor surface). Yes. If the vertical movement direction of the elevating unit 13 is the Z axis, XYZ orthogonal coordinates as shown in the figure can be assumed.
  • the power supply box 14 supplies necessary power to each part of the system.
  • the dental X-ray hybrid machine 1 includes two arms 15 and 16 extending in the X-axis direction (that is, laterally) from the lifting unit of the lifting unit 13.
  • the two arms 15 and 16 are in the Y-axis direction.
  • Is equipped with a rotation mechanism 13D that can rotate the two arms 15 and 16 independently of each other, that is, at different speeds.
  • the X-ray tube 21 and the detector 22 are each equipped with a slit (aperture) 23 for forming X-rays into a fan shape or a cone shape on the front surface of the X-ray tube 21 on the X-ray irradiation side.
  • the rotation mechanism 13D and arms 15 and 16, for the X-ray tube 21 and the detector 22, the support means for driving rotatably supported independently of one another are constructed.
  • the X-ray tube 21 is configured as a rotating anode type X-ray tube using, for example, tungsten as an anode material.
  • the X-ray tube 21 has a dotted X-ray focal point (for example, a diameter of 0.1 mm to 0.5 mm) FP.
  • the X-ray tube 21 emits pulsed X-rays in response to driving power supplied from a high-voltage generator described later.
  • X-rays exposed from the X-ray focal point FP of the X-ray tube 21 are narrowed by the slit 23 and formed into a fan-shaped X-ray beam. Thereafter, the X-ray beam passes through the jaw JW of the subject P and is attenuated, and the transmitted X-ray beam reflecting the attenuated state is incident on the detector 22.
  • the jaw portion JW of the subject P is positioned at a predetermined position in the three-dimensional imaging space IS defined between the X-ray tube 21 and the detector 22. For this reason, the X-ray tube 21 and the detector 22 face each other (face to face) across the jaw.
  • the irradiated X-ray beam passes through the jaw JW (such as a dentition) and is then detected by the detector 22. Since the two arms 15 and 16 are rotationally driven by the rotation mechanism 13D at the time of imaging, the X-ray tube 21 and the detector 22 rotate around the jaw part along a predetermined circular orbit around the rotation center O. During the rotation, irradiation and detection of the X-ray beam are executed at predetermined intervals.
  • the X-ray tube 21 and the detector 22 are respectively driven to rotate along circular trajectories Tx and Td centered on the rotation center O determined in advance on the system side.
  • the radii Dx and Dd from the rotation center O to the circular trajectories Tx and Td are set to different values in consideration of X-ray exposure, detection accuracy, downsizing of the apparatus, mechanical interference with the patient, and the like. (See FIG. 2).
  • the reason why the distance (radius Dd) from the rotation center O to the detector 22 is smaller than that (radius Dx) from the rotation center O to the X-ray tube 21 is that the position of the detector 22 is set as much as possible. This is to reduce the attenuation of the incident intensity of X-rays.
  • the distance (radius Dx) from the rotation center O to the X-ray tube 21 is set to a value that can ensure the distance between the X-ray tube and the skin defined by the standard.
  • the X-ray tube 21 and the detector 22 are always opposed to each other (facing to each other), and irradiation and detection of X-rays along a plurality of predetermined desired X-ray paths with respect to the jaw JW (dentition) are performed.
  • the X-ray tube 21 and the detector 22 are independently driven at different angular velocities.
  • the opposing arm portions 15A and 16A including the X-ray tube 21 and the detector 22 out of the arms 15 and 16 have the axis It can be independently rotated (rotated) around AXs and AXd (see FIGS. 1 to 3).
  • rotation driving mechanisms 15B and 16B such as motors are provided on the arms 15 and 16, respectively.
  • the drive control of the rotation drive mechanisms 15B and 16B is executed by a controller of the console 17 described later.
  • the positions of the intersection position C and the axis AXd are matched in the Y-axis direction. Further, the circular trajectories Tx and Td shown in FIG. 3 follow the positions of the axes AXs and AXd, respectively, when viewed in the YZ plane.
  • the detector 22 has an array (sensor circuit) of a plurality of detection modules B1 to Bm in which X-ray imaging elements are two-dimensionally arranged.
  • the plurality of detection modules B1 to Bm are created as blocks independent of each other, and are mounted in a predetermined shape (for example, a rectangular shape) on a substrate (not shown) to form the entire detector 22.
  • a plurality of detection modules B1 to Bm are provided in two dimensions in the vertical (X-axis) and horizontal (Y-axis) directions (15 in the vertical direction, horizontal direction) while providing a certain gap between the individual modules. 8, together with arranging by further placing the 5 upper and lower ends), they are arranged obliquely inclined by an angle ⁇ with respect to the scanning direction O Y individual modules. This angle ⁇ is set to about 14 °, for example.
  • the surface of a rectangular shape (in the case of CT imaging) having a small length ratio (in the case of CT imaging) or a large ratio of length to width, that is, an elongated rectangular shape (in the case of panoramic imaging), is created by the plurality of detection modules B1 to Bm.
  • An X-ray detection surface 22A is formed. Since the detection modules B1 to Bm are arranged obliquely, the X-ray detection surface 22A is formed so as to follow (inscribe) the inside of each detection surface of the plurality of modules B1 to Bm.
  • the structure of the detector 22 having this detection module arranged obliquely and the processing of the detection signal by the sub-pixel method are known, for example, from WO2012 / 0886648A1.
  • a plurality of modules arranged in a column arranged in a line on the left side in FIG. 4 function as modules for panoramic imaging.
  • the opening area for panoramic photography is indicated by reference numeral 22B.
  • a module group of a two-dimensional array formed by all the modules except the two modules at the upper and lower ends of the left side row and the remaining modules functions as a module for CT imaging.
  • the opening area for CT imaging is indicated by reference numeral 22A.
  • the module group for panoramic imaging or CT imaging is selected by controlling the opening area of the slit 23.
  • Reference numeral AXd in FIG. 4 is a central axis when the detector 22 itself rotates (rotates).
  • Individual detection modules B1 ( ⁇ Bm) are made of a semiconductor material that directly converts X-rays into electrical pulse signals. For this reason, the detector 22 is a photon counting X-ray detector of a direct conversion method using a semiconductor.
  • the detector 22 is formed as an array of a plurality of detection modules B1 to Bm.
  • Each detection module Bm includes a detection circuit Cp (see FIG. 5) for detecting X-rays and a data counting circuit 51 n (see FIG. 5) stacked together with the detection circuit Cp, as is well known.
  • the detection circuit Cp includes, for each detection module, a semiconductor layer that directly converts X-rays into an electrical signal, and a charging electrode and a collecting electrode that are respectively stacked on both sides (not shown). X-rays are incident on the charged electrode.
  • the charged electrode is a common electrode, and a high bias voltage is applied between the charged electrodes.
  • the semiconductor layer and the collecting electrode are divided into a grid pattern, and by this division, a plurality of small regions are formed that are arranged in a two-dimensional array at a certain distance from each other.
  • a plurality of stacked bodies of semiconductor cells C see FIGS. 4 and 5
  • collecting electrodes arranged in a two-dimensional manner on the charged electrode are formed.
  • the plurality of stacked bodies to form a plurality of pixels S n arranged in a two dimensional grid pattern.
  • a plurality of pixels S n (n 1 to N) occupying a predetermined area necessary for the detector 22 by the whole of the plurality of detection modules B1 to Bm (however, depending on the opening area 22A at the time of CT imaging: see FIG. 4). ) Is formed.
  • the plurality of pixels S n constitutes a pixel group Cp (refer to FIG. 5).
  • each pixel S n is, for example, 200 [mu] m ⁇ 200 [mu] m, the pixel size is set to a detectable value X-rays incident as a set of multiple photons.
  • Each pixel S n is responsive to incident of each photon of X-ray, and outputs an electrical pulse of amplitude corresponding to the energy possessed by the photon. That is, each pixel S n may convert the X-rays incident on that pixel directly, into electric signals.
  • the detector 22 the photon constituting the cone beam-like X-rays incident, counts for each pixel S n which constitute the detection surface of the detector 22, the quantity of electricity that reflects the count value Data is output at a high frame rate of, for example, 75 fps. This data is also called frame data.
  • the semiconductor material of the semiconductor layer that is, the semiconductor cell C, cadmium telluride semiconductor (CdTe semiconductor), cadmium zinc telluride semiconductor (CdZnTe semiconductor (CZT semiconductor)), silicon semiconductor (Si semiconductor), thallium bromide (T1Br) Mercury iodide or the like is used.
  • this semiconductor cell is composed of a cell that combines a scintillator material that is subdivided into columns and optically shielded from each column, and a photoelectric converter composed of a combination of fine avalanche photodiodes. May be.
  • the size of each pixel S n described above (200 [mu] m ⁇ 200 [mu] m) is adapted to a sufficiently small value that is capable of detecting X-rays as photons (particles).
  • the size capable of detecting X-rays as the particles is “between electric pulses responding to each incident when a plurality of radiation (for example, X-ray) particles are successively incident at or near the same position.
  • the occurrence of the superposition phenomenon (also called pile-up) is defined as “a size that can be substantially ignored or whose amount is predictable”.
  • X-ray particle countdown also called pile-up count loss
  • the size of the pixel S n to form the X-ray detector 22 the magnitude of which can be regarded as the counting loss does not occur or does not substantially occur, or are set to an extent counting the drop amount can be estimated .
  • Each charge amplifier 52 is connected to each current collecting electrode of each semiconductor cell S, charges up the current collected in response to the incidence of X-ray particles, and outputs it as a pulse signal of electric quantity.
  • the output terminal of the charge amplifier 52 is connected to a waveform shaping circuit 53 whose gain and offset can be adjusted.
  • the waveform of the detected pulse signal is processed with the previously adjusted gain and offset to shape the waveform.
  • the gain and offset of the waveform shaping circuit 53 in consideration of the variation in non-uniformity and the circuit characteristics for charge-charge characteristic for each pixel S n of semiconductor cell C, is calibrated. As a result, it is possible to increase the output of the waveform shaping signal from which non-uniformity has been eliminated, and the relative threshold setting accuracy.
  • each pixel S n i.e., the characteristics reflecting the energy value of the X-ray particle pulse signal waveform formatted output from the waveform shaping circuit 53 for each collection channel CN n is substantially incident Have. Therefore, the variation between the collection channels CN n is greatly improved.
  • the output terminal of the waveform shaping circuit 53 is connected to the comparison input terminals of the plurality of comparators 54 1 to 54 4 .
  • analog amount threshold values voltage values
  • FIG. 6 shows the magnitude relationship (th 1 ⁇ th 2 ⁇ th 3 ⁇ threshold) between the peak value (representing energy) of the pulse voltage generated in response to the input of one X-ray photon and the threshold values th 1 to th 4. th 4 ) schematically.
  • the reason for this comparison is to examine which region (discrimination) the energy value of the incident X-ray particle enters among the energy regions set in advance divided into a plurality. A determination is made as to which of the analog amount threshold values th 1 to th 4 exceeds the peak value of the pulse signal (that is, the energy value of the incident X-ray photon). Thereby, the energy area
  • the lowest analog amount threshold th 1 is usually used to prevent detection of disturbance, noise due to circuits such as the semiconductor cell S and the charge amplifier 52, or low-energy radiation that is not necessary for imaging. Is set as the threshold value.
  • the number of thresholds i.e., the number of comparators is not necessarily limited to four, three, including the amount of the analog amount threshold th 1, or may be five or more.
  • Analog amount threshold th 1 ⁇ th 4 described above, specifically, given from the calibration computing unit 38 of the console 17 for each pixel S n in a digital value through the interface 31, i.e., for each acquisition channels. Therefore, the reference input terminals of the comparators 54 1 to 54 4 are connected to the output terminals of the four D / A converters 57 1 to 574, respectively.
  • the D / A converter 57 1-57 4 is connected to the threshold receiving end T 1 via the latch circuits 58 ( ⁇ T N), the interface 31 of the threshold receiving end T 1 ( ⁇ T N) console 17 It is connected.
  • the latch circuit 58 latches the thresholds th 1 ′ to th 4 ′ of digital quantities given from the threshold applier 41 via the interface 31 and the threshold receiving end T 1 (to T N ) at the time of imaging, and the corresponding D / are output to a converters 57 1-57 4. Therefore, the D / A converters 57 1 to 57 4 can supply the commanded analog amount thresholds th 1 to th 4 to the comparators 54 1 to 54 4 as voltage amounts, respectively.
  • FIG. 7 schematically shows an X-ray spectrum when an appropriate material is used for the anode material of the X-ray tube 21.
  • the horizontal axis indicates X-ray energy, and the vertical axis indicates the incidence frequency of X-ray photons. This incidence frequency is a factor representative of the count value (count) or intensity of X-ray photons.
  • the analog amount threshold th i is an analog voltage applied to the comparator 54 i in each discrimination circuit DS i
  • the energy threshold TH i is an analog value for discriminating the X-ray energy (keV) of the energy spectrum.
  • the waveform shown in FIG. 7 shows a continuous spectrum of the energy of X-rays exposed from an X-ray tube that is normally used, for example, using tungsten as an anode material.
  • the count value (count) on the vertical axis is an amount proportional to the photon generation frequency corresponding to the energy value on the horizontal axis
  • the energy value on the horizontal axis is an amount depending on the tube voltage of the X-ray tube 21.
  • the first analog quantity threshold th 1 is set as the X-ray photon count non-counting area (the area where there is no meaningful X-ray information for counting and the circuit noise is mixed) and the lower first to set corresponding to the energy region ER 1 and energy threshold value TH 1 capable discrimination of.
  • the second and third analog amount threshold values th 2 and th 3 are set so as to sequentially provide the second and third energy threshold values TH 2 and TH 3 which are higher than the first energy threshold value TH 1 .
  • These energy thresholds TH i are determined so that one or more subjects as a reference are assumed and the count value for a predetermined time for each energy region is substantially constant.
  • the output of the comparator 54 1-54 3, as shown in FIG. 5, is connected to the input ends of the plurality of counters 56 1-56 4.
  • Each of the counters 56 1-56 4 counts up every time the output of the comparator 54 1-54 3 (pulse) is turned on. As a result, the number of X-ray photons having energy equal to or higher than the energy value discriminated into the energy region ER 1 (to ER 4 ) that each counter 56 1 (to 56 4 ) takes charge of is accumulated value W 1 ′ ( it can be counted for each pixel S n as ⁇ W 4 ').
  • noise components smaller than the energy threshold TH 1 defined as the input energy counting limit are not counted. This noise component corresponds to an energy value signal belonging to the non-countable region ERx in FIG.
  • V dec ⁇ th 1 the minimum threshold th 1 (V dec ⁇ th 1 )
  • the number of photons is counted. If the relationship is V dec ⁇ th 1 , the outputs of all the comparators 54 1 to 54 4 are turned on. That is, the count value W 1 of all the counters 56 1 ⁇ 56 4 ' ⁇ W 4' is counted up.
  • the output of the comparator module 54 4 of the fourth stage is turned on, only the counter 56 4 count value W 4 'of the fourth stage is counted up.
  • the energy value of the photon related to the input is a noise component belonging to the region ER 4 exceeding the third high energy region ER 3 , disturbance, etc., which is not suitable for imaging or counting.
  • the count value W 4 ′ can be used as information for estimating or excluding photons that have caused a superposition phenomenon or simultaneously incident photons.
  • X-ray photon number W 1 to W 4 belonging to each of the first through fourth energy regions ER 1 to ER 4 the actual count value W 1 ' ⁇ W 4' Is obtained by calculation (subtraction).
  • a circuit for deciphering which energy region ER1 to ER4 the current event, that is, the incidence of X-ray photons belongs becomes unnecessary from the combination of turning on and off the outputs of the comparators 54 1 to 54 4 . This simplifies the circuit configuration mounted on the data counting circuit 51 n of the detector 22.
  • the meaning of “collection” for each energy region of the number of X-ray photons according to the present application is the meaning of “obtaining by calculation” from the actual count value as described above, and for each energy region as in a modification example described later. Both meanings of directly “counting” the number of X-ray photons are included.
  • the counter 56 1-56 4 described above start and stop signals is supplied via a start-stop terminal T2 from below to the controller of the console 17. Counting for a fixed time is managed from the outside using a reset circuit included in the counter itself.
  • the interface 31 receives these count values and stores them in a storage unit to be described later.
  • the data counting circuit 51 n is integrally constructed in CMOS by the semiconductor cell C and the data counting circuit 51 n corresponding to N pixels S n described above ASIC (Application Specific Integrated Circuit).
  • the data counting circuit 51 n may be configured as a circuit or device separate from the group of semiconductor cells C.
  • the plurality of detection modules B1 to Bm are connected to a scintillator array in which a plurality of scintillators processed into columnar shapes are bundled, and receives light incident from the scintillator.
  • a plurality of avalanche photodiodes are mounted on the light receiving surface, and the avalanche photodiodes belonging to the region are electrically connected by a quenching element for each rectangular region having a predetermined size corresponding to the cell on the light receiving surface.
  • a silicon photomultiplier is used to a silicon photomultiplier.
  • the material of the scintillator is LFS (lutetium silicate), GAGG: Ce (gadolinium aluminum gallium garnet), LuAG: Pr (praseodymium-added lutetium aluminum garnet), or the same decay time and light emission amount as the LuAG: Pr. It may be a material having a specific gravity.
  • the console 17 includes an interface (I / F) 31 that performs input and output of signals, a controller 33 that is communicably connected to the interface 31 via a bus 32, and a first storage unit 34, a data processor 35, a display unit 36, an input unit 37, a calibration calculator 38, a second storage unit 39, ROMs 40A to 40D, and a threshold value assigner 41.
  • the controller 33 controls the drive of the X-ray hybrid machine 1 according to a program given in advance to the ROM 40A. This control includes sending a command value to the high voltage generator 42 that supplies a high voltage to the X-ray tube 21 and a drive command to the calibration calculator 38.
  • the first storage unit 34 stores frame data and image data that are count values sent from the detector 22 via the interface 31.
  • the data processor 35 operates based on a program given in advance to the ROM 40B under the control of the controller 33. During CT imaging, the data processor 35 performs the CT image reconstruction process by processing the frame data stored in the first storage unit 34 by a desired CT reconstruction method. On the other hand, at the time of panoramic photography, the data processor 35 operates tomosynthesis based on a known arithmetic method called “shift and add” to the frame data stored in the first storage unit 34. To implement. Thereby, a CT image or a panoramic image of the oral cavity of the subject P is obtained.
  • the display unit 36 is responsible for displaying an image to be created, information indicating the operation status of the apparatus, and operator operation information given via the input unit 37.
  • the input device 37 is used by an operator to give information necessary for imaging to the apparatus.
  • the calibration computing unit 38 under the control of the controller 33, operating under program built in advance in ROM40C, giving for each energy discriminator circuit for each pixel S n in the data counting circuit, X-rays energy Calibrate the digital quantity threshold for discrimination.
  • the threshold value applicator 41 calls the threshold value of the digital quantity stored in the second storage unit 39 for each pixel and for each discrimination circuit at the time of imaging, and uses the threshold value as a command value as an interface. 31 to the detector 22. In order to execute this process, the threshold value assigner 41 executes a program stored in advance in the ROM 40D.
  • the controller 33, the data processor 35, the calibration calculator 38, and the threshold value assigner 41 are all provided with a CPU (central processing unit) that operates according to a given program. Those programs are stored in advance in each of the ROMs 40A to 40D.
  • the data processor 35 reads the count value stored in the first storage unit 34 in response to an operator command from the input device 37, and uses this count value for image processing and substance identification.
  • the commanded process such as the above process and the measurement process is executed.
  • the image processing includes, for example, generation of a panoramic image of a cross section of a dentition based on a tomosynthesis method in “panoramic imaging” and generation of a tomographic image based on a desired reconstruction method in “CT imaging”. .
  • substance identification includes identification (specification) of types and states of a plurality of substances constituting the jaw using beam hardening information.
  • This CT image reconstruction and substance identification process is one of the features of the present application. Although the process will be described below representing the features noteworthy were discriminated into a plurality of first to third energy regions ER 1 to ER 3, respectively, the count value of the X-ray photons from each pixel S n W 1 This means that a set of ( ⁇ W 3 ) (which is also collected data) is obtained. For this reason, as in the prior art, the data processor 35 applies moderately high weights to the set of the count values W 1 to W 3 and applies the data obtained by adding them to each other to the tomosynthesis method or the CT reconstruction method. Can be hung.
  • processing can be performed without weighting.
  • ER 1 to ER 3 are discriminated in the respective first to third energy regions ER 1 to ER 3, set to CT reconstruction for each area the count value W 1 of each pixel S n ( ⁇ W 3), this result It is also possible to generate a scatter diagram from the obtained reconstruction data and to identify the substance from the scatter diagram.
  • step S1 the controller 33 determines whether to perform CT imaging or panoramic imaging interactively with the operator.
  • step S2 panoramic imaging of the jaw of the subject P is performed by a known method to obtain, for example, a panoramic image of the dentition.
  • step S1 determines whether the determination in step S1 is “execution of CT imaging”.
  • the controller 33 cooperates with the data processor 35 to sequentially execute the steps after step S3.
  • the controller 33 determines the scanning method interactively with the operator or according to the default setting (step S3).
  • a full scan and a half scan are prepared.
  • the full scan is a method of collecting data while a pair of the X-ray tube 21 and the detector 22 makes a round (360 degrees) around the jaw.
  • the half scan is a method of collecting data while the pair of the X-ray tube 21 and the detector 22 rotates around the jaw part by a half turn (180 degrees).
  • the controller 33 instructs the X-ray scan to the jaw of the subject P positioned in the imaging space (step S4).
  • the pair of the X-ray tube 21 and the detector 22 starts to rotate around the jaw, and data collection based on the commanded scanning method is started (step S5).
  • cone beam-shaped X-rays are continuously or pulsedly irradiated from the X-ray tube 21, and the X-rays pass through the jaw.
  • the transmitted X-ray is detected by the detector 22.
  • the opening of the slit 23 is controlled so that the size of the projection surface of the transmitted X-ray with respect to the detector 22 matches the size and shape of the detection surface 22A.
  • Data processor 35 determines the X-ray photon number with energy values belonging to each of the first to third energy regions ER 1 to ER 3 performs the subtraction for each pixel S n (step S7).
  • the controller 33 interactively determines with the operator whether or not to reconstruct the CT image using the data collected as described above (step S8).
  • the data processor 35 is instructed to perform the reconstruction process.
  • the data processor 35 have been discriminated to each of the first to third energy regions ER 1 to ER 3, an appropriate weighting to projection data composed of the count value W 1 (- W 3) of each pixel S n in and (step S9), and the weighted projection data is added to each other for each pixel S n to form a projection data composed of a set count value, a predetermined reconstruction method the projection data (e.g., FBP method) Reconfiguration is performed (step S10).
  • a predetermined reconstruction method the projection data e.g., FBP method
  • the high (or low) weighted by the projection data consisting of the count value W 1 of each pixel S n which is discriminated in the first energy area ER 1 each pixel is discriminated in the third energy regions ER 3 S a low (or high) weighted by the projection data consisting of the count value W 3 of n.
  • This weighting can be implemented in various ways, and may be reconfigured without weighting.
  • the generated CT image is displayed on the display 36 (step S11).
  • step S8 the controller 33 further interactively communicates with the operator using the data collected as described above to identify a plurality of types of substances constituting the jaw. Is determined (step S12).
  • the substance identification is a process for specifying the type of each substance.
  • step S12 determines to perform substance identification
  • step S12 determines to perform substance identification
  • step S13 determines to perform subsequent reconstruction processing.
  • the data processor 35 which is discriminated in each of the first to third energy regions ER 1 to ER 3, CT re for each region using the projection data consisting count W k of each pixel S n Configure (step S13: see FIG. 10).
  • step S13 see FIG. 10
  • three sets of CT images IM 1 to IM 3 in the 3D (volume) space including the jaws are reconstructed for the three energy regions ER 1 to ER 3 from the first to the third .
  • the data of the CT images IM 1 to IM 3 are stored in the first storage unit 34 so as to be readable.
  • the controller 33 determines whether or not to display the three sets of CT images IM 1 to IM 3 as they are (step S14). If this display is desired (step S14, YES), one or more sets of the CT images IM 1 to IM 3 are displayed on the display 36 in an appropriate manner (step S15).
  • step S16 it is further determined whether to execute the substance identification process interactively (step S16).
  • the scatter diagram creation process is left to the data processor 35.
  • the data processor 35 reads the data of the three CT images IM 1 to IM 3 from the first storage unit 34, and creates a two-dimensional scatter diagram shown in FIG. 11 (step S17).
  • This two-dimensional scatter diagram includes a relative attenuation index RAI (Relative Attenuation Index) shown on the vertical axis forming one dimension and a quality change index SDI (Spectrum Deformation Index) shown on the horizontal axis forming another dimension.
  • RAI Relative Attenuation Index
  • SDI Spectrum Deformation Index
  • the relative attenuation index RAI is a index corresponding to (pixel distinguished from the S n of the detector) CT values each pixel S B forming a three-dimensional volume space, in the present embodiment, the pixel S B
  • the relative attenuation index RAI represents the relative attenuation with respect to the reference material an amount based on a sum of at least two energy bands all the pixel values for each pixel S B.
  • the line quality change index is a line for each pixel S B based on a division between a pixel value of a higher energy band of at least two energy bands and a pixel value of the same pixel of a lower energy band. Indicates a change in quality.
  • the quality change index SDI may be defined as W 2 / W 1 or W 3 / W 2 .
  • the data processor 35 reads the data of the relative attenuation index RAI and the radiation quality change index SDI from the first storage unit 34, creates a two-dimensional scatter diagram from these data, and displays the scatter diagram on the display 36. (Step S18). An example of this display is shown in FIG. The drawing the two-dimensional scatter, for each pixel S B, the corresponding point of the relative attenuation index RAI and radiation quality variation index SDI is displayed by dots.
  • the data processor 35 analyzes the dispersion state of the dots shown on the scatter diagram, and various substances (soft tissue, gingiva, alveolar bone, cortical bone, tooth, metal, etc.) forming the jaw. Is identified (step S19).
  • the scatter diagram of the dot points on the scatter diagram is the scatter diagram previously obtained by CT imaging for each substance in advance (that is, for each device or for each system regardless of the device).
  • a dispersion position with noise added is analyzed from a dispersion table indicating a distribution area, and grouping is performed according to the distribution characteristics. Further, the position of the group of dot groups is compared with reference data in the first storage unit 34 in advance to determine which group of dot groups corresponds to which substance.
  • display data to the user is generated, for example, by coloring each determined substance with a different color, adding an annotation AN with characters, or indicating a group of dot groups grouped for each substance by ROI. (Step S20).
  • the identification result includes fluctuation components such as noise, it is desirable to perform noise reduction processing such as smoothing.
  • the data processor 35 displays the prepared display data on the display 36 (step S21).
  • An example of this display is shown in FIG. In this example, each substance is indicated by a different symbol, an irregular ROI, and an annotation indicating the substance name.
  • this display data is preferably generated and displayed in different display modes for each type of identified substance. If expressed in a generalized manner, it is preferable to generate and display one or a plurality of elements of hue, saturation, brightness, and pattern that are different from each other in combination. Among them, displaying with different patterns means, for example, displaying a two-dimensional region identified with a specific substance with diagonal lines, coloring only the boundary surface, and displaying the inside with black dots.
  • each pixel S B is any substance constituting the three-dimensional space becomes an imaging target comprising jaws have been identified.
  • the data processor 35 creates three-dimensional shape data representing the actual jaw using the identification information (step S22), and displays the created three-dimensional shape data on the display 36 (step S23).
  • the three-dimensional shape data is also preferably generated and displayed by combining one or more elements of hue, saturation, brightness, and pattern, as described above.
  • the three-dimensional shape data may be data indicating a physical shape of only a designated substance. This three-dimensional shape data is stored in the first storage unit 34.
  • the three-dimensional shape data is transmitted to an external dental CAD / CAM system for an impression under the control of the controller 33 in response to an instruction from the operator (step S24).
  • the processing in steps S1 to S6 in FIG. 9 executed by the controller 33 constitutes scanning means, and the processing in steps S12 and S13 in FIG. 9 executed by the data processor 35 constitutes reconstruction means. is doing.
  • the processing of steps S16 to S19 in FIG. 9 corresponds to the substance identifying means, and among these, the processing of step S17 corresponds to the scatter diagram creating means.
  • the processing in steps S20 to S23 in FIG. 9 corresponds to the image generation means, among which the processing in step S22 constitutes a three-dimensional shape data creation means, and the processing in step S23 constitutes a three-dimensional shape display means.
  • step S24 corresponds to transmission means.
  • a collecting means is formed by the data counting circuit 51n and the step S7 of FIG.
  • a scatter diagram is created from the reconstructed CT image for each of the three energy regions ER 1 to ER 3 given to the X-ray photons, and based on this scatter diagram.
  • the type of substance that forms the jaw can be identified. Based on the identification result, three-dimensional shape data of each substance in the jaw can be created.
  • the SDI elements are added one-dimensionally rather than simply judging from RAI alone. Will improve.
  • the RAI may be W3 / W2 or W2 / W1 as well as W3 / W1.
  • This three-dimensional shape data is extremely effective scan data for a dental CAD / CAM system.
  • the CAD / CAM system is a system in which a CAD (Computer-Aided (Assisted) Design) system and a CAM (Computer-Aided (Assisted) Manufacturing) are integrated. That is, a system for designing and manufacturing dental artifacts using computer graphics technology.
  • a dental CAD / CAM system measurement of the dentition model and the patient's teeth is necessary, and a measurement model and a three-dimensional measurement model (three-dimensional shape data) of the patient's teeth are constructed from the measurement results. .
  • the type of substance constituting the jaw is directly identified from the three-dimensional volume data reconstructed based on the projection data collected by the photon counting detector 22. Based on the identification result, three-dimensional shape data indicating the structure of the jaw is created. As described above, the reconstructed three-dimensional volume data is created based on pixel data having a wide dynamic range from soft tissue to hard tissue. For this reason, the drawing ability of the three-dimensional shape data indicating the soft tissue and hard tissue of the oral cavity is also high. That is, an accurate impression can be made.
  • the jaw data necessary for the impression of creating the tooth mold can be obtained directly from the 3D data obtained by CT, and the data necessary for the “CT impression” corresponding to the conventional optical impression. Can be conveniently provided.
  • surgical guides for implant surgery that were conventionally designed by CAD / CAM represented by optical impressions can be created from CT images, and fusion with surgical guides can be easily performed with high accuracy from CT images of hard tissues. This is possible only with a CT scanner. This eliminates the need to purchase expensive optical equipment for optical impressions, and can provide a surgical guide in a dental clinic at a low cost in a short time only by purchasing a CT scanner.
  • an image that makes the soft tissue appear stable in this way it can also be used for a diagnosis in which a soft tissue lesion or a positional relationship between the soft tissue and the hard tissue is important, which cannot be obtained by conventional X-ray medical care. Can do.
  • the highest energy threshold of the four energy thresholds is set to the X-ray tube voltage, and the other three thresholds divide the range of energy information contributing to imaging into three equal parts.
  • Installed and information on the uppermost energy band (This information is information on the number of photons due to the superposition phenomenon because the energy band is a band equal to or higher than the value corresponding to the X-ray tube voltage, and is not worthy of imaging. It is also possible to obtain a highly accurate reconstructed image optimized for soft tissue and hard tissue by reconstructing the image by dividing it into three energy bands without using only (some).
  • a scatter diagram composed of a two-dimensional “relative attenuation index RAI ⁇ radiation quality change index SDI” is used to identify the type of substance present in the jaw. Compared to the case where only the relative attenuation index RAI is used, the scatter diagram is used to increase the noise resistance of the substance identification and improve the identification accuracy.
  • the coordinates A and B are representative value positions representative of the scattering regions of the substances A and B.
  • the representative values are, for example, the mode value position, the median value position, the arithmetic mean value position, or the center of gravity. Suppose that it is a position.
  • the coordinates A (SDI A , RAI A ) and B (SDI B , RAI B ) are relatively distant from each other with respect to the line quality change index SDI (distance L SDI ), and can be easily distinguished.
  • the relative attenuation index RAI is very close (distance L RAI ).
  • Distance L RAI RAI A -RAI B
  • Distance L AB > distance L RAI .
  • the scattering characteristics of the substances A and B are theoretically represented by one point on the scatter diagram.
  • noise includes factors such as photon noise, detector sensitivity unevenness, mechanism operation accuracy, and reconstruction error.
  • each scattering characteristic of the substances A and B is not actually a point but is dispersed in a certain range (region).
  • RAI relative attenuation index
  • the relative attenuation index RAI is substantially equal, and RAIA ⁇ RAIB, which is almost indistinguishable on the axis of the relative attenuation index RAI. Even if it is attempted to discriminate between the two substances A and B using only the relative attenuation index RAI, it is difficult to be buried in noise.
  • both substances A and B can be distinguished in consideration of the information of the distance LSDI. That is, even if the X-ray absorption coefficients of the substances A and B are very similar, they can be distinguished from each other, and the identification accuracy is improved.
  • the data counting circuit 151 n alone constitutes a collecting means.
  • the data counting circuit 151 n as shown in FIG. 16, the energy region distribution circuit 55 is disposed between the four-stage comparator 51 1-51 4 and 4-stage counter 56 1-56 4. That is, as in the embodiment described above, comparator 51 1-51 output 4 is unlike intact counter 56 1-56 4 respectively input to the configuration, the energy region distribution circuit 55 comparator 51 1-51 4
  • the energy range ER 1 to ER 4 to which the energy associated with the incidence of each X-ray photon belongs is decoded, and the energy range ER 1 (to ER 4 to which the energy value belongs. ) Is sent to the counter 56 1 ( ⁇ 56 4 ) that is in charge of counting.
  • the data counting circuit 51 n of the above-described embodiment calculates (collects) the count value for each energy region of the final X-ray photon by calculation, but the data counting circuit 151 n according to this modification directly calculates it. Can be counted.
  • the output terminals of the comparators 54 1 to 54 3 are connected to the energy region distribution circuit 55.
  • This energy region distribution circuit 55 compares the output of the plurality of comparators 54 1 to 54 4 , that is, the pulse voltage corresponding to the detected energy value of the X-ray particles and the analog amount threshold th 1 (to th 4 ). And the energy range ER 1 to ER 4 is classified.
  • noise components smaller than the energy threshold TH 1 defined as the input energy counting limit are not counted. This noise component corresponds to an energy value signal belonging to the non-countable region ERx in FIG.
  • V dec ⁇ th 1 the minimum threshold th 1 (V dec ⁇ th 1 )
  • the number of photons is counted. If the relationship is th 1 ⁇ V dec ⁇ th 2 ( ⁇ th 4 ), only the output of the first-stage comparator 54 1 is turned on, and the energy value of the photon related to the input is in the lower energy region. Decoded as ER 1 discriminated. If the relationship of th 2 ⁇ V dec ⁇ th 3 ( ⁇ th 4 ) is established, the outputs of only the first-stage and second-stage comparators 54 1 and 54 2 are turned on, and the energy value of the photon related to the input is What is discriminated into the medium second energy region ER 2 is decoded.
  • the outputs of only the first-stage, second-stage, and third-stage comparators 54 1 , 54 2 , 54 3 are turned on, and the photon energy associated with the input value is decrypted to be discriminated in the high third energy region ER 3. Furthermore, if the relationship of th 4 ⁇ V dec is satisfied, the outputs of all the comparators 54 1 to 54 4 are turned on, and the energy value of the photon related to the input is not suitable for imaging or counting, the third high It is deciphered that the noise component belongs to the region ER 4 exceeding the energy region ER 3 , disturbance, and the like.
  • the energy region distribution circuit 55 sends a pulse signal indicating the discrimination result to any of the counters 56 1 to 56 4 in accordance with the discrimination result by the comparators 54 1 to 54 4 described above. For example, if there is an event to be discriminated in the energy region ER 1, and sends a pulse signal to the counter 56 1 in the first stage. If there is an event to be discriminated in the energy region ER 2, it sends a pulse signal to the second-stage counter 56 2. If events are distinguished in the energy region ER 3, and sends a pulse signal to the counter 56 3 of the third stage. If events are distinguished in the energy region ER 4, it sends a pulse signal to the counter 56 4 of the fourth stage.
  • This counter 56 4 of the fourth stage may not be provided in consideration.
  • step S7 of FIG. 9 executed by the data processor 35 described in the above embodiment is not necessary.
  • the imaging target of the X-ray CT apparatus is a living body, that is, a subject (patient's jaw). That is, the patient's head is positioned in the imaging space and the jaw is CT scanned.
  • an impression (material) taken in the oral cavity or a dental model made by pouring a model material such as gypsum into the impression is positioned at a predetermined position in the imaging space, and the impression or CT scan of the dental model.
  • an X-ray contrast agent is added to a material such as a mold preparation (impression material) or gypsum for creating a dental model.
  • This X-ray contrast agent is a component that enhances the contrast difference with air with respect to at least one of the above-described RAI (relative attenuation index) and SDI (line quality change index) for X-rays.
  • RAI relative attenuation index
  • SDI line quality change index
  • components of such an X-ray contrast agent include powdered iodine, barium, strontium, titanium oxide, and zinc oxide.
  • one or more types are added in advance to the material for making the impression or the tooth model.
  • the CT scan slice width is set as thin as possible.

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Abstract

[Problem] To accurately and simply execute a CT reconstruction in order to identify substance type in an imaged jaw or the like of a patient. [Solution] This x-ray imaging device is equipped with an x-ray tube and a photon-counting detector. The detector is equipped with a pixel group obtained by two-dimensionally positioning pixels for outputting an electrical pulse according to the photons of an x-ray, and a counting circuit for capturing the number of x-ray photons per pixel. This counting circuit has N number (N≥3) of energy thresholds assigned thereto in order to discriminate the energy for each of the x-ray photons. As a result, the electrical pulse outputted from each pixel is discriminated by electrical thresholds corresponding to the N number of energy thresholds. Consequently, the number of x-ray photons is captured for each pixel according to each of the (N-1) number of energy bands. When CT imaging, imaging data based on the number of x-ray photons is captured for each of at least two energy bands among the (N-1) number of energy regions. On the basis of this imaging data, a CT image is reconstructed for each energy band.

Description

X線撮像装置及びX線撮像方法X-ray imaging apparatus and X-ray imaging method
 本発明は、X線を対象の所望の撮像部位に照射し、その対象を透過してきた放射線を検出し、その検出データに基づいて撮像部位を構成する組織を同定するX線撮像装置に係り、特に、光子計数(フォトンカウンティング)型の検出器が検出した、X線の複数のエネルギ帯それぞれのX線の光子(フォトン)の数に応じたX線吸収データに基づいて撮像部位の組織同定、形状データなどのデータ収集、断層像の画像化などの機能を提供するX線撮像装置及びX線撮像方法に関する。 The present invention relates to an X-ray imaging apparatus that irradiates a desired imaging region of an object, detects radiation transmitted through the object, and identifies a tissue constituting the imaging region based on the detection data, In particular, tissue identification of an imaging region based on X-ray absorption data corresponding to the number of X-ray photons (photons) in each of a plurality of X-ray energy bands detected by a photon counting (photon counting) type detector, The present invention relates to an X-ray imaging apparatus and an X-ray imaging method that provide functions such as data collection of shape data and imaging of tomographic images.
 近年、X線やガンマ線などの放射線を用いて対象物の内部構造や機能を診断・撮影する装置における技術進歩は目覚しいものがある。この種の装置には放射線を検出する検出器が必須であり、この放射線検出器の性能向上も上述の技術進歩の一翼を担っている。とくに、検出信号をデジタル形式で出力する、いわゆるデジタル化を始め、画素の精細化及び検出面の大形化が進んでいる。 In recent years, there have been remarkable technological advances in devices that diagnose and image the internal structure and functions of objects using radiation such as X-rays and gamma rays. A detector for detecting radiation is indispensable for this type of apparatus, and the improvement of the performance of this radiation detector plays a part in the above-mentioned technological progress. In particular, so-called digitization, in which detection signals are output in a digital format, is becoming increasingly finer and the detection surface is becoming larger.
 この放射線検出器の放射線検出法についても、従来からの積分法(積分モード)に加え、光子計数法(フォトンカウンティング法)と呼ばれる検出法も注目されている。この光子計数法は、従来では、核医学の分野におけるガンマ線検出器に採用されていたものである(例えば、特許文献1を参照)。一方、近年、画像のエンハンス能の向上、メタルアーチファクトの削減、ビームハードニングの影響を軽減などの効果を得るために、この光子計数法をX線検出器に適用する事例も報告されている。 As for the radiation detection method of this radiation detector, in addition to the conventional integration method (integration mode), a detection method called a photon counting method (photon counting method) is also attracting attention. This photon counting method has been conventionally used in gamma ray detectors in the field of nuclear medicine (see, for example, Patent Document 1). On the other hand, in recent years, there have been reports of cases in which this photon counting method is applied to an X-ray detector in order to obtain effects such as enhancement of image enhancement capability, reduction of metal artifacts, and reduction of the effects of beam hardening.
 この種の事例の1つとして特許文献2で提案されたものが知られている。つまり、「複数の画素のそれぞれに入射した放射線を光子と見做して当該粒子のエネルギに応じた電気信号を出力する光子計数型検出器を備え、この検出器が出力した各画素の信号に基づいて放射線のエネルギスペクトル上の複数のエネルギ領域に分類される当該放射線の光子数の計数値を演算し、この演算された画素毎の複数のエネルギ領域それぞれの計数値に当該エネルギ領域別に与えられた重み係数の重み付けを施し、この重み付けされた画素毎の複数のエネルギ領域それぞれの計数値を互いに加算し、この加算データを画素毎の放射線画像生成用データとして出力する放射線検出装置」である。 The one proposed in Patent Document 2 is known as one example of this type. In other words, “the photon counting type detector that outputs the electric signal corresponding to the energy of the particle by regarding the radiation incident on each of the plurality of pixels as a photon is provided. Based on this, the count value of the number of photons of the radiation classified into a plurality of energy regions on the energy spectrum of the radiation is calculated, and the calculated count value of each of the plurality of energy regions for each pixel is given for each energy region. The radiation detection apparatus that performs weighting of the weighting factors, adds the count values of the plurality of weighted energy regions for each pixel, and outputs the added data as radiation image generation data for each pixel.
 このように、光子計数型のX線検出器の場合、入射するX線光子のそれぞれが持つエネルギを弁別する閾値が1個以上(好適には複数個)、用意される。この閾値によりエネルギの範囲が規定されるので、各X線光子のエネルギがどのエネルギ範囲に属するかを判定することができる。この判定の結果、それぞれのエネルギ範囲に弁別されたX線光子数が計数される。この計数値の情報が画像の画素値として反映される。 Thus, in the case of a photon counting X-ray detector, one or more (preferably a plurality of) thresholds for discriminating the energy of each incident X-ray photon are prepared. Since the energy range is defined by this threshold value, it is possible to determine to which energy range the energy of each X-ray photon belongs. As a result of this determination, the number of X-ray photons discriminated into the respective energy ranges is counted. This count value information is reflected as the pixel value of the image.
 一方、近年、X線装置を用いて測定対象に含まれる物質の種類を同定(又は識別、特定)しようとする試みもなされている。この同定の試みとして、上述のように、エネルギ帯に分けたエネルギ情報が出力できる光子計数型X線平面検出器を用いるものがある(例えば、論文に係る非特許文献1及び非特許文献2を参照)。具体的には、この光子計数型X線平面検出器をCTスキャナに搭載し、検出したエネルギ情報を用いて物質の同定(識別)を行うものである。この同定法の場合、研究レベルでは興味深い結果が出ている。しかし、本技術は研究レベルに留まり、性能面のバランスの悪さと生産性の点で実用化には至っていない。 On the other hand, in recent years, attempts have been made to identify (or identify or identify) the types of substances contained in the measurement object using an X-ray apparatus. As an attempt of this identification, as described above, there is one using a photon counting X-ray flat panel detector capable of outputting energy information divided into energy bands (for example, Non-Patent Document 1 and Non-Patent Document 2 related to the paper). reference). Specifically, this photon counting X-ray flat panel detector is mounted on a CT scanner, and the substance is identified (identified) using the detected energy information. In the case of this identification method, interesting results have been obtained at the research level. However, this technology remains at the research level and has not yet been put into practical use in terms of poor performance balance and productivity.
 また、CTスキャナを用いて物質同定を行う手法も知られている。この場合には、別々の管電圧を供給するX線管と、これらのX線管とそれぞれ対を成す2つの検出器とが搭載される。そこで、2つの検出器で検出されるX線エネルギの相違を利用して、物質の識別を行う。また、X線管と検出器の対は必ずしも複数である必要はなく、1対のX線管と検出器でもよい。この構成の場合、X線管に供給する管電圧を例えば2つの間で、収集のスピードよりも速いスピードで高速に切り換え、2つの管電圧の元で収集される2種類の画像を切り分けて取り出し、物質同定を行うこともできる。 Also known is a method of identifying a substance using a CT scanner. In this case, an X-ray tube for supplying separate tube voltages and two detectors each paired with these X-ray tubes are mounted. Therefore, the substance is identified using the difference in X-ray energy detected by the two detectors. The number of X-ray tube / detector pairs is not necessarily plural, and a pair of X-ray tubes and detectors may be used. In this configuration, for example, the tube voltage supplied to the X-ray tube is switched between two at high speed at a speed faster than the acquisition speed, and two types of images collected under the two tube voltages are separated and extracted. Substance identification can also be performed.
 このようなCTスキャナを用いた物質同定の背景には、CTスキャナがいわゆるCT値を求める装置であることがある。つまり、物質の種類が異なれば、CT値は異なり、また、同じ物質であっても、与えるX線エネルギ(管電圧)が異なれば、CT値が異なるので、この違いを利用して物質を特定しようというものである。 In the background of substance identification using such a CT scanner, there is a case where the CT scanner is a device for obtaining a so-called CT value. In other words, the CT value differs if the type of substance is different, and even if the substance is the same, the CT value will differ if the X-ray energy (tube voltage) applied is different. It is to try.
特開平11-109040JP-A-11-109040 特開2006-101926JP 2006-101926 A
 しかしながら、異なる2つの管電圧を印加する2つのX線管を搭載する手法の場合、既に製品化されているが、精度の高い物質同定には限界がある。そのために比較的識別の容易なCT値の差の大きな識別に応用されているのが現状で微妙な物質の差を同定するには精度が不十分である。その理由は、X線が連続スペクトラムであるため、2つのX線エネルギ帯にオ-バーラップが存在してエネルギ帯の情報が正しく取り出せない。このため同定精度の限界があるからである。 However, in the case of a method in which two X-ray tubes that apply two different tube voltages are mounted, it has already been commercialized, but there is a limit to accurate substance identification. For this reason, it is applied to identification with a large difference in CT values that is relatively easy to identify, and the accuracy is insufficient to identify subtle differences in substances. The reason is that, since the X-ray has a continuous spectrum, there is an overlap between the two X-ray energy bands, and the energy band information cannot be correctly extracted. This is because the identification accuracy is limited.
 また、3つ以上の管電圧を切り替えようと思えば、2個以上の管球を追加して3個以上のX線管を使用するか、さらに高速に管電圧を切り替える必要がある。一方、SN比を保とうと思えば、X線量が増え、X線被曝の点で好ましくない。 If you want to switch three or more tube voltages, you need to add two or more tubes and use three or more X-ray tubes, or switch the tube voltage at a higher speed. On the other hand, if the S / N ratio is to be maintained, the X-ray dose increases, which is not preferable in terms of X-ray exposure.
 本発明は、上記事情に鑑みてなされたもので、被検者の顎部等の撮像対象を撮像する歯科用CTスキャナの機能を備えたX線撮像装置において、光子計数型の検出器により検出されたエネルギ領域毎の投影データを使って、撮像対象に存在する物質の種類を同定(又は識別、特定)するためのCT再構成処理を精度良く且つ簡便に実行できるX線撮像装置を提供することを、その目的とする。 The present invention has been made in view of the above circumstances, and is detected by a photon counting type detector in an X-ray imaging apparatus having a dental CT scanner function for imaging an imaging target such as a subject's jaw. Provided is an X-ray imaging apparatus capable of accurately and simply executing CT reconstruction processing for identifying (or identifying and identifying) the type of substance existing in an imaging target using the projection data for each energy region. That is the purpose.
 上記目的を達成するため、本発明の一つの側面に係るX線撮像装置は、白色X線を曝射するX線管と、入射するX線の光子に応じた電気パルスを出力する画素を2次元的に配置した画素群を有する検出回路と、前記X線の連続エネルギに対してエネルギ閾値をN個(N≧4)以上与え、且つ前記各画素から出力される前記電気パルスを前記N個のエネルギ閾値により弁別するとともに、前記X線の光子数を、前記N個のエネルギ閾値で分けられ且つ当該N個のエネルギ閾値の相互間に在る「N-1」個のエネルギ帯域のそれぞれに応じて画素毎に収集する収集手段と、を有する光子計数型の検出器と、前記X線管と前記検出器を互いに対向させるとともに、CT撮影時には当該X線管と当該検出器を撮像対象の周りに回転可能に支持する支持手段と、前記CT撮影時には前記X線管と前記検出器を前記撮像対象の周りに、指示されたスキャン法に基づいて回転させるスキャン手段と、前記「N-1」個のエネルギ帯域のうち少なくとも2個のエネルギ帯域それぞれに対して、前記収集手段により収集された前記X線の光子数に基づく投影データにCT(computed tomography)用の再構成処理を施して当該少なくとも2個のエネルギ帯域それぞれのCT画像を再構成する再構成手段と、を備えることを特徴とする。 In order to achieve the above object, an X-ray imaging apparatus according to one aspect of the present invention includes two X-ray tubes that emit white X-rays and two pixels that output an electric pulse corresponding to incident X-ray photons. A detection circuit having a dimensionally arranged pixel group and N or more energy thresholds (N ≧ 4) are given to the continuous energy of the X-ray, and the N electric pulses output from each pixel are given. And the number of photons of the X-rays is divided into the N energy thresholds divided by the N energy thresholds and between the N energy thresholds. And a photon counting detector having a collecting means for collecting each pixel, the X-ray tube and the detector face each other, and at the time of CT imaging, the X-ray tube and the detector A support that is rotatably supported around Means, scanning means for rotating the X-ray tube and the detector around the object to be imaged based on the instructed scanning method at the time of the CT imaging, and at least one of the “N−1” energy bands For each of the two energy bands, the projection data based on the number of photons of the X-rays collected by the collecting means is subjected to reconstruction processing for CT (computed tomography), and each of the at least two energy bands. Reconstructing means for reconstructing a CT image.
 また別の側面によれば、白色X線を曝射するX線管と、入射するX線の光子に応じた電気パルスを出力する画素を2次元的に配置した画素群を有する検出回路と、前記X線の光子数を画素毎に収集する収集手段と、を有する光子計数型の検出器と、前記X線管と前記検出器を互いに対向させるとともに、CT撮影時には当該X線管と当該検出器を撮像対象の周りに回転可能に支持する支持手段と、前記CT撮影時には前記X線管と前記検出器を前記撮像対象の周りに、指示されたスキャン法に基づいて回転させるスキャン手段と、を備えたX線撮像装置におけるX線撮像方法が提供される。このX線撮像方法では、前記収集手段に前記X線の連続エネルギに対してエネルギ閾値をN個(N≧3)以上与えた状態で前記CT撮像を行って、前記各画素から出力される前記電気パルスを前記収集手段により前記N個のエネルギ閾値で弁別させ、前記X線の光子数を、前記N個のエネルギ閾値で分けられ且つ当該N個のエネルギ閾値の相互間に在る「N-1」個のエネルギ帯域のそれぞれに応じて画素毎に収集し、前記「N-1」個のエネルギ帯域のうち少なくとも2個のエネルギ帯域それぞれに対して、前記収集手段により収集された前記X線の光子数に基づく投影データにCT(computed tomography)用の再構成処理を施して当該少なくとも2個のエネルギ帯域それぞれのCT画像を再構成する。 According to another aspect, a detection circuit having an X-ray tube that emits white X-rays, and a pixel group in which pixels that output electric pulses corresponding to incident X-ray photons are two-dimensionally arranged; A photon counting detector having a collecting means for collecting the number of photons of the X-ray for each pixel, the X-ray tube and the detector facing each other, and at the time of CT imaging, the X-ray tube and the detection A support unit that rotatably supports the imaging device around the imaging target, and a scanning unit that rotates the X-ray tube and the detector around the imaging target based on the instructed scanning method during the CT imaging, An X-ray imaging method is provided in an X-ray imaging apparatus comprising: In this X-ray imaging method, the CT imaging is performed in a state where N energy thresholds (N ≧ 3) or more are given to the acquisition means with respect to the continuous energy of the X-ray, and the CT image output from each pixel is output. An electric pulse is discriminated by the N energy thresholds by the collecting means, and the number of photons of the X-ray is divided by the N energy thresholds and “N−” between the N energy thresholds. The X-rays collected for each pixel in accordance with each of the “1” energy bands, and collected by the collecting means for each of at least two energy bands of the “N−1” energy bands. The projection data based on the number of photons is subjected to reconstruction processing for CT (computed tomography) to reconstruct CT images of the at least two energy bands.
 本発明において「物質を同定(識別、特定)する」とは、投影データを再構成したCT画像から、被検者の顎部等の撮像対象に在る物質の種類を同定することを意味し、その対象となる物質の厚さ(相対的、絶対的な厚さ)を知ることも含まれる概念である。この物質の同定には、X線を粒子、すなわち光子として捉え、そのX線光子をそのエネルギ領域の毎に計数した計数値に基づくX線透過情報と、X線粒子が呈するビームハードニングと呼ばれる線質硬化の情報とを用いる。ビームハードニングとは、X線の高エネルギ成分の方がその低エネルギ成分の方より相対的に大きくなる現象で、一般に、線質が固くなるという表現を使う(線質硬化現象)。この線質硬化の現象は、通常、物質の厚さが大きいほど、また物質の密度が高いほど強く(大きく)なる。また物質によっては透過情報では差がないが、線質硬化現象では差がある場合も多くある。また逆に、線質硬化現象では差がないが、透過情報では差が出るケースもある。 In the present invention, “identifying (identifying, identifying) a substance” means identifying the type of substance present in an imaging target such as a subject's jaw from a CT image obtained by reconstructing projection data. It is a concept that includes knowing the thickness (relative and absolute thickness) of the target substance. This material identification is called X-ray transmission information based on a count value obtained by capturing X-rays as particles, that is, photons, and counting the X-ray photons for each energy region, and beam hardening exhibited by the X-ray particles. And information on curing of wire quality. Beam hardening is a phenomenon in which the high energy component of X-rays is relatively larger than the low energy component, and generally uses the expression that the quality of the wire becomes harder (wire quality hardening phenomenon). This phenomenon of linear hardening usually becomes stronger (larger) as the thickness of the substance is larger and the density of the substance is higher. Moreover, although there is no difference in transmission information depending on the substance, there are many cases in which there is a difference in the radiation hardening phenomenon. Conversely, there is a case where there is no difference in the line hardening phenomenon but there is a difference in the transmission information.
 好適には、前記再構成手段により再構成された前記少なくとも2個のエネルギ帯域それぞれの前記画像の画素値に基づいて前記撮像対象を形成する物質の種類を同定する物質同定手段、を備える、ことである。 Preferably, the apparatus includes a substance identification unit that identifies the type of substance that forms the imaging target based on pixel values of the image of each of the at least two energy bands reconstructed by the reconstruction unit. It is.
 例えば、前記物質同定手段は、前記少なくとも2個のエネルギ帯域全ての前記画像の画素値の総和に基づく量であって参照物質に対する相対的な減衰を表す画素毎の相対減衰指数と、前記少なくとも2個のエネルギ帯域のうちの高い方のエネルギ帯域の前記画像の画素値と低い方のエネルギ帯域の前記画像の画素値との間の除算に基づく画素毎の線質変化指数とを含む2次元以上の次元を持つ散布図を作成する散布図作成手段を、備えることが望ましい。 For example, the substance identifying means is a quantity based on a sum of pixel values of the image of all the at least two energy bands, and a relative attenuation index for each pixel representing a relative attenuation with respect to a reference substance, and the at least 2 Two or more dimensions including a pixel quality change index for each pixel based on a division between a pixel value of the image in the higher energy band of the energy bands and a pixel value of the image in the lower energy band It is desirable to provide a scatter diagram creating means for creating a scatter diagram having the following dimensions.
 また更に、前記N個のエネルギ閾値のうちの最も高い閾値は、前記X線光子のエネルギ値の所望上限値に設定されている、ことが望ましい。 Furthermore, it is desirable that the highest threshold value among the N energy threshold values is set to a desired upper limit value of the energy value of the X-ray photon.
 本発明によれば、被検者の顎部等の撮像対象をCT撮影するときに、光子計数型の検出器を用いて、X線の光子数が「N-1」個(N≧3)のエネルギ帯域それぞれに応じて画素毎に計数される。この「N-1」個のエネルギ帯域のうち少なくとも2個のエネルギ帯域それぞれに対して、計数されたX線の光子数に基づく投影データにCT(computed tomography)用の再構成処理が施される。これにより、当該少なくとも2個のエネルギ帯域それぞれの画像が再構成される。このため、このエネルギ帯域に得られる、X線光子数を反映したCT画像データを、例えば、相対減衰指数と線質変化指数とを含む2次元以上の次元を持つ散布図の作成に使用可能になる。この散布図は撮像対象に含まれる各種物質に応じた散布特性を示すので、これを用いて物質の同定が可能になる。したがって、従来の様々な物質同定法に比べて、精度良く簡便に、撮像対象の物質の種類を同定(識別、判別)できる。 According to the present invention, when performing CT imaging of an imaging target such as a subject's jaw, the number of X-ray photons is “N−1” (N ≧ 3) using a photon counting detector. It counts for every pixel according to each energy band. Reconstruction processing for CT (computed tomography) is performed on projection data based on the counted number of photons of X-rays for each of at least two energy bands among the “N−1” energy bands. . Thereby, the image of each of the at least two energy bands is reconstructed. For this reason, CT image data reflecting the number of X-ray photons obtained in this energy band can be used to create a scatter diagram having two or more dimensions including, for example, a relative attenuation index and a quality change index. Become. Since this scatter diagram shows the scatter characteristics according to various substances included in the imaging target, the substance can be identified using this scatter diagram. Therefore, the type of substance to be imaged can be identified (identified and discriminated) more accurately and easily than various conventional substance identification methods.
 添付図面において、
図1は、一実施形態に係るCT撮像機能を備えたX線ハイブリッド機の斜視図、 図2は、上記X線ハイブリッド機のX線管及び検出器の配置構成を説明する図、 図3は、上記X線ハイブリッド機のX線管及び検出器の配置構成を、当該X線管及び検出器の回転可能な方向及びそれらの正対状態と共に説明する別の図、 図4は、検出器の構成の概略を説明する配置例の図、 図5は、検出器の電気的な構成を説明するブロック図、 図6は、光子計数型の検出器に与える、X線フォトンの入射に応答して検出される電気パルスと閾値との関係を説明するグラフ、 図7は、X線のフォトンの入射頻度(計数値)に対するエネルギスペクトラムと弁別回路による与えるエネルギ領域との関係例を説明するグラフ、 図8は、X線ハイブリッド機全体の電気的な構成の概略を示すブロック図、 図9は、実施形態で実行される物質同定の処理の流れを説明するフローチャート、 図10は、エネルギ領域とその領域毎の再構成処理との関係を説明する模式図、 図11は、実施形態で採用した散布図の次元を示すグラフ、 図12は、実施形態の物質同定の処理による作成された散布図の一例を模式的に示すグラフ、及び、 図13は、散布図上で顎部の物質の種類を同定した様子を模式的に示すグラフである。 図14は、2次元の散布図を用いて2つの物質を弁別するときの有利さを説明するグラフである。 図15は、2次元の散布図を用いて2つの物質を弁別するときの有利さを説明する別のグラフである。 図16は、検出器の変形例を示す回路図である。
In the accompanying drawings,
FIG. 1 is a perspective view of an X-ray hybrid machine having a CT imaging function according to an embodiment. FIG. 2 is a diagram for explaining the arrangement of the X-ray tube and the detector of the X-ray hybrid machine, FIG. 3 is another view for explaining the arrangement of the X-ray tube and the detector of the X-ray hybrid machine together with the rotatable directions of the X-ray tube and the detector and their facing states. FIG. 4 is a diagram of an arrangement example illustrating the outline of the configuration of the detector, FIG. 5 is a block diagram illustrating the electrical configuration of the detector. FIG. 6 is a graph for explaining the relationship between an electrical pulse detected in response to the incidence of X-ray photons and a threshold value, which is given to a photon counting detector. FIG. 7 is a graph for explaining an example of the relationship between the energy spectrum with respect to the incidence frequency (count value) of X-ray photons and the energy region given by the discrimination circuit; FIG. 8 is a block diagram showing an outline of the electrical configuration of the entire X-ray hybrid machine, FIG. 9 is a flowchart for explaining the flow of substance identification processing executed in the embodiment; FIG. 10 is a schematic diagram illustrating the relationship between the energy region and the reconstruction process for each region. FIG. 11 is a graph showing dimensions of a scatter diagram adopted in the embodiment. FIG. 12 is a graph schematically showing an example of a scatter diagram created by the substance identification process of the embodiment; FIG. 13 is a graph schematically showing how the types of substances in the jaw are identified on the scatter diagram. FIG. 14 is a graph illustrating the advantage of discriminating two substances using a two-dimensional scatter diagram. FIG. 15 is another graph illustrating the advantages of discriminating two substances using a two-dimensional scatter diagram. FIG. 16 is a circuit diagram showing a modification of the detector.
 以下、添付図面を参照して、本発明の実施形態を説明する。 Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.
 (第1の実施形態)
 図1~図13を参照して、本発明に係るX線CT装置の第1の実施形態を説明する。
(First embodiment)
A first embodiment of an X-ray CT apparatus according to the present invention will be described with reference to FIGS.
 このX線CT装置は、撮像対象としての被検者の顎部(歯列を含む)のパノラマ画像を撮像するX線パノラマ撮影機能も備えた歯科用のX線ハイブリッド機として構成されている。つまり、この1台の歯科用のX線ハイブリッド機は、1つのハードウェアを有しながら、オペレータがソフトウェアの種類を「パノラマ撮影」及び「CT撮影」の中から選択することで、その同じハードウェアを使って両撮像を選択的に実施することができるように構成されている。 This X-ray CT apparatus is configured as a dental X-ray hybrid machine that also has an X-ray panoramic imaging function that captures a panoramic image of a subject's jaw (including a dentition) as an imaging target. In other words, this single dental X-ray hybrid machine has one piece of hardware, but the operator selects the type of software from “panoramic photography” and “CT photography” so that the same hardware can be used. Both imaging can be selectively performed using the wear.
 「パノラマ撮像」を選択したときには、被検体の顎部の擬似的な3次元断面像(画像それ自体は2次元画像であるが、歯列などの撮影部位の形状に応じて3次元的に表示される断面像)を撮影できる。「CT撮像」を選択したときには、被検体の顎部のCT画像を得ることができる。両機能共に、被検体の顎部の周りを回るX線管及びX線検出器(以下、単に検出器と呼ぶ)を使用する。X線管から照射されたX線は顎部を透過して検出器で検出される。この検出器は、後述するように、X線(実際には、スリット(絞り))によりファン状又はコーン状に成形されたX線ビーム)を光子(粒子)の束であるとして捉えてその光子の数に応じた計数情報を得る光子計数(フォトンカウンティング)型の検出器である。このため、顎部を透過したX線透過データはその光子(フォトン)の数を反映している。なお、ファン状のX線ビームはパノラマ撮影時に、またコーン状のX線ビームはCT撮影時に使用される。 When “Panorama Imaging” is selected, a pseudo three-dimensional cross-sectional image of the jaw of the subject (the image itself is a two-dimensional image, but is displayed in a three-dimensional manner according to the shape of the imaging part such as a dentition) Can be taken). When “CT imaging” is selected, a CT image of the jaw of the subject can be obtained. Both functions use an X-ray tube and an X-ray detector (hereinafter simply referred to as a detector) that go around the jaw of the subject. X-rays emitted from the X-ray tube pass through the jaw and are detected by a detector. As will be described later, this detector captures X-rays (actually, X-ray beams formed into a fan shape or a cone shape by a slit (aperture)) as a bundle of photons (particles), and the photons It is a photon counting (photon counting) type detector that obtains counting information according to the number of the photons. For this reason, the X-ray transmission data transmitted through the jaw reflects the number of photons. The fan-shaped X-ray beam is used for panoramic imaging, and the cone-shaped X-ray beam is used for CT imaging.
 そこで、この歯科用のX線ハイブリッド機は、「パノラマ画像」を得る場合、顎部の所望の又は指定された断面の画像データをトモシンセシス法の下で生成するように動作するように構成されている。これにより、その断面のパノラマ画像のデータが作成される。このパノラマ撮影自体は公知であるので、本実施形態ではその説明を簡略化又は省略する。 Therefore, this dental X-ray hybrid machine is configured to operate to generate image data of a desired or specified cross section of the jaw under the tomosynthesis method when obtaining a “panoramic image”. Yes. Thereby, panoramic image data of the cross section is created. Since this panoramic photography itself is known, the description thereof is simplified or omitted in the present embodiment.
 なお、本実施形態に係るX線ハイブリッド機は歯科用の撮影装置として説明しているが、このX線ハイブリッド機の用途は、必ずしも歯科に限られない。その他の撮影用途として、乳房撮影、耳鼻咽喉撮影、手足の骨・関節部分など、様々な部位の撮影に適用できる。また、本人同定のための死体鑑定や、非破壊検査などの用途にも適用することができる。 In addition, although the X-ray hybrid machine which concerns on this embodiment is demonstrated as a dental imaging device, the use of this X-ray hybrid machine is not necessarily restricted to dentistry. As other imaging applications, it can be applied to imaging various parts such as mammography, otolaryngology, bones and joints of limbs. It can also be applied to uses such as corpse identification for identity identification and nondestructive inspection.
 図1に、本実施形態に係る歯科用のX線ハイブリッド機1の外観を示す。 FIG. 1 shows an appearance of a dental X-ray hybrid machine 1 according to this embodiment.
 この歯科用のX線ハイブリッド機1は、キャスター11を装着した台座12と、この台座12に搭載された昇降ユニット13及び電源ボックス14と、コンソール17を備える。昇降ユニット13は、その内部に昇降機構(図示せず)を備え、同ユニットの上側の昇降部を台座12(つまり床面)に対して電動で所定範囲の中で上下動可能に構成されている。この昇降ユニット13の上下動方向をZ軸とすると、図示のようなXYZ直交座標を想定できる。なお、電源ボックス14はシステムの各部に必要な電力を供給する。 The dental X-ray hybrid machine 1 includes a pedestal 12 on which a caster 11 is mounted, an elevating unit 13 and a power supply box 14 mounted on the pedestal 12, and a console 17. The elevating unit 13 includes an elevating mechanism (not shown) therein, and the upper elevating unit of the unit is configured to be movable up and down within a predetermined range electrically with respect to the base 12 (that is, the floor surface). Yes. If the vertical movement direction of the elevating unit 13 is the Z axis, XYZ orthogonal coordinates as shown in the figure can be assumed. The power supply box 14 supplies necessary power to each part of the system.
 また、この歯科用X線ハイブリッド機1は、昇降ユニット13の昇降部からX軸方向(つまり、横方向に伸びた2つのアーム15,16を備える。この2つのアーム15,16はY軸方向に沿って見た場合、共に、略L字状に形成され、それらアーム15,16夫々の一端部が互いに重なるように重合され、昇降部の側面に取り付けられている。昇降ユニット13の内部には、それら2つのアーム15,16を互いに独立して、すなわち互いに異なる速度で回転させることができる回転機構13Dが装備されている。上記2つのアーム15,16の夫々の先端部分には、X線管21及び検出器22がそれぞれ装備されている。X線管21のX線照射側の前面には、X線をファン状又はコーン状に成形するスリット(絞り)23が配設される。回転機構13Dとアーム15,16により、X線管21及び検出器22に対する,相互に独立して駆動可能に支持する支持手段が構成される。 In addition, the dental X-ray hybrid machine 1 includes two arms 15 and 16 extending in the X-axis direction (that is, laterally) from the lifting unit of the lifting unit 13. The two arms 15 and 16 are in the Y-axis direction. Are both formed in a substantially L shape, are superposed so that one end of each of the arms 15 and 16 overlaps each other, and is attached to the side surface of the elevating unit. Is equipped with a rotation mechanism 13D that can rotate the two arms 15 and 16 independently of each other, that is, at different speeds. The X-ray tube 21 and the detector 22 are each equipped with a slit (aperture) 23 for forming X-rays into a fan shape or a cone shape on the front surface of the X-ray tube 21 on the X-ray irradiation side. The rotation mechanism 13D and arms 15 and 16, for the X-ray tube 21 and the detector 22, the support means for driving rotatably supported independently of one another are constructed.
 X線管21は例えばタングステンを陽極材に用いた回転陽極型X線管として構成される。X線管21は点状のX線焦点(例えば径が0.1mm~0.5mm)FPを有する。このX線管21は、後述する高電圧発生装置から供給される駆動電力に応答してパルスX線を曝射する。X線管21のX線焦点FPから曝射されたX線は、スリット23で絞られてファン状のX線ビームに成形される。このX線ビームは、その後、被検者Pの顎部JWを透過して減衰し、その減衰状態を反映した透過X線ビームが検出器22に入射する。 The X-ray tube 21 is configured as a rotating anode type X-ray tube using, for example, tungsten as an anode material. The X-ray tube 21 has a dotted X-ray focal point (for example, a diameter of 0.1 mm to 0.5 mm) FP. The X-ray tube 21 emits pulsed X-rays in response to driving power supplied from a high-voltage generator described later. X-rays exposed from the X-ray focal point FP of the X-ray tube 21 are narrowed by the slit 23 and formed into a fan-shaped X-ray beam. Thereafter, the X-ray beam passes through the jaw JW of the subject P and is attenuated, and the transmitted X-ray beam reflecting the attenuated state is incident on the detector 22.
 撮影時には、図2に示すように、X線管21と検出器22との間に画成される3次元の撮影空間ISの所定位置に被検者Pの顎部JWが位置決めされる。このため、X線管21と検出器22は顎部を挟んで互いに対向(正対)する。照射されたX線ビームは顎部JW(歯列など)を透過した後、検出器22により検出される。撮影時には回転機構13Dにより2つのアーム15,16が回転駆動されるので、回転中心Oを中心にX線管21と検出器22は顎部の周りを各々、所定の円形軌道に沿って回転し、その回転中に所定間隔でX線ビームの照射及び検出が実行される。 At the time of imaging, as shown in FIG. 2, the jaw portion JW of the subject P is positioned at a predetermined position in the three-dimensional imaging space IS defined between the X-ray tube 21 and the detector 22. For this reason, the X-ray tube 21 and the detector 22 face each other (face to face) across the jaw. The irradiated X-ray beam passes through the jaw JW (such as a dentition) and is then detected by the detector 22. Since the two arms 15 and 16 are rotationally driven by the rotation mechanism 13D at the time of imaging, the X-ray tube 21 and the detector 22 rotate around the jaw part along a predetermined circular orbit around the rotation center O. During the rotation, irradiation and detection of the X-ray beam are executed at predetermined intervals.
 YZ面に対向するX軸方向に沿ってみた場合、X線管21及び検出器22は、予めシステム側で定めた回転中心Oを中心とする円形の軌道Tx,Tdに沿ってそれぞれ回転駆動される。この回転中心Oから円形軌道Tx,Tdまでの半径Dx、DdはX線被ばく、検出精度、装置の小形化、患者との機械的な干渉などを考慮して、互いに異なった値に設定されている(図2参照)。本実施形態では、Dx≠Ddであって、特にDx>Ddに設定されている。回転中心Oから検出器22までの距離(半径Dd)の方が、回転中心OからX線管21までのそれ(半径Dx)よりも小さい理由は、検出器22の位置を極力、顎部JWに接近させ、X線の入射強度の減弱を少なくするためである。回転中心OからX線管21までの距離(半径Dx)は、規格で定められたX線管・皮膚間距離を確保できる値に設定されている。 When viewed along the X-axis direction facing the YZ plane, the X-ray tube 21 and the detector 22 are respectively driven to rotate along circular trajectories Tx and Td centered on the rotation center O determined in advance on the system side. The The radii Dx and Dd from the rotation center O to the circular trajectories Tx and Td are set to different values in consideration of X-ray exposure, detection accuracy, downsizing of the apparatus, mechanical interference with the patient, and the like. (See FIG. 2). In the present embodiment, Dx ≠ Dd, and particularly Dx> Dd. The reason why the distance (radius Dd) from the rotation center O to the detector 22 is smaller than that (radius Dx) from the rotation center O to the X-ray tube 21 is that the position of the detector 22 is set as much as possible. This is to reduce the attenuation of the incident intensity of X-rays. The distance (radius Dx) from the rotation center O to the X-ray tube 21 is set to a value that can ensure the distance between the X-ray tube and the skin defined by the standard.
 このため、X線管21及び検出器22を常に互いに対向(正対)させ、且つ、顎部JW(歯列)に対する予め定めた複数の所望のX線パスに沿ったX線の照射及び検出を実行させるため、X線管21及び検出器22は互いに異なる角速度で独立して駆動される。 Therefore, the X-ray tube 21 and the detector 22 are always opposed to each other (facing to each other), and irradiation and detection of X-rays along a plurality of predetermined desired X-ray paths with respect to the jaw JW (dentition) are performed. In order to perform the above, the X-ray tube 21 and the detector 22 are independently driven at different angular velocities.
 なお、上述した「互いに対向」とは、図3に示すように、X軸方向に沿って見た場合、X線管21の点状のX線焦点FPから照射されてスリット23によりコーン状に成形されたX線ビームの照射範囲と、検出器22のX線検出面22A(後述する)とが一致している状態を言う。特に、そのX線ビームが、そのX線検出面の幅方向における、あるモジュールBm(後述する)の中心位置Cに90°で交差する軸Tを含む状態を「正対している状態」と呼ぶ(図3参照)。 Note that “opposing each other” described above is a cone-like shape that is irradiated from the dotted X-ray focal point FP of the X-ray tube 21 when viewed along the X-axis direction as shown in FIG. The state in which the irradiation range of the shaped X-ray beam and the X-ray detection surface 22A (described later) of the detector 22 coincide with each other. In particular, a state in which the X-ray beam includes an axis T that intersects the center position C of a module Bm (described later) at 90 ° in the width direction of the X-ray detection surface is referred to as a “facing state”. (See FIG. 3).
 このため、上述した「常に互いに対向(又は正対)」を実現するため、前記アーム15,16のうち、X線管21、検出器22を内蔵している対向アーム部分15A,16Aは、軸AXs、AXdを中心にそれぞれ独立して回動(自転)可能になっている(図1~図3参照)。そのためのモータ等の回転駆動機構15B,16Bがアーム15,16にそれぞれ装備されている。この回転駆動機構15B,16Bの駆動制御は後述するコンソール17のコントローラにより実行される。 For this reason, in order to realize the above-mentioned “always opposite (or facing each other)”, the opposing arm portions 15A and 16A including the X-ray tube 21 and the detector 22 out of the arms 15 and 16 have the axis It can be independently rotated (rotated) around AXs and AXd (see FIGS. 1 to 3). For this purpose, rotation driving mechanisms 15B and 16B such as motors are provided on the arms 15 and 16, respectively. The drive control of the rotation drive mechanisms 15B and 16B is executed by a controller of the console 17 described later.
 なお、本実施形態では、Y軸方向において交差位置Cと軸AXdの位置を一致させている。また、図3に示す円軌道Tx,Tdを辿るのは、それぞれ、YZ面で見たときの前述した軸AXs、AXdの位置である。 In the present embodiment, the positions of the intersection position C and the axis AXd are matched in the Y-axis direction. Further, the circular trajectories Tx and Td shown in FIG. 3 follow the positions of the axes AXs and AXd, respectively, when viewed in the YZ plane.
 検出器22は、図4に示すように、X線撮像素子を2次元に配列した複数の検出モジュールB1~Bmのアレイ(センサ回路)を有する。複数の検出モジュールB1~Bmは互いに独立したブロックとして作成され、それらを基板(図示せず)上に所定形状(例えば矩形状)に実装して検出器22の全体が作成される。 As shown in FIG. 4, the detector 22 has an array (sensor circuit) of a plurality of detection modules B1 to Bm in which X-ray imaging elements are two-dimensionally arranged. The plurality of detection modules B1 to Bm are created as blocks independent of each other, and are mounted in a predetermined shape (for example, a rectangular shape) on a substrate (not shown) to form the entire detector 22.
 なお、複数の検出モジュールB1~Bmは、個々のモジュールの間は一定の隙間を設けつつ、縦(X軸)及び横(Y軸)の2次元に複数個(縦方向に15個、横方向に8個、更に上下端それぞれ5を配置)ずつ並べるとともに、個々のモジュールをスキャン方向Oに対して角度θだけ斜めに傾けて配置している。この角度θは例えば約14°に設定される。この複数の検出モジュールB1~Bmが作る縦横の長さの比が小さい矩形状(CT撮影の場合)又は縦横の長さの比が大きい、つまり、細長い長方形状(パノラマ撮影の場合)の表面がX線検出面22Aを成している。検出モジュールB1~Bmを斜めに配置しているため、X線検出面22Aは複数のモジュールB1~Bmの個々の検出面の内側を辿る(内接する)ように形成されている。 A plurality of detection modules B1 to Bm are provided in two dimensions in the vertical (X-axis) and horizontal (Y-axis) directions (15 in the vertical direction, horizontal direction) while providing a certain gap between the individual modules. 8, together with arranging by further placing the 5 upper and lower ends), they are arranged obliquely inclined by an angle θ with respect to the scanning direction O Y individual modules. This angle θ is set to about 14 °, for example. The surface of a rectangular shape (in the case of CT imaging) having a small length ratio (in the case of CT imaging) or a large ratio of length to width, that is, an elongated rectangular shape (in the case of panoramic imaging), is created by the plurality of detection modules B1 to Bm. An X-ray detection surface 22A is formed. Since the detection modules B1 to Bm are arranged obliquely, the X-ray detection surface 22A is formed so as to follow (inscribe) the inside of each detection surface of the plurality of modules B1 to Bm.
 この斜め配置の検出モジュールを有する検出器22の構造及びその検出信号のサブピクセル法による処理は、例えばWO2012/086648A1公報により知られている。 The structure of the detector 22 having this detection module arranged obliquely and the processing of the detection signal by the sub-pixel method are known, for example, from WO2012 / 0886648A1.
 なお、図4における左側一列に並んだ縦列配置の複数のモジュールはパノラマ撮像用のモジュールとして機能する。このパノラマ撮影用の開口面積は符号22Bで示す。また、この左側一列のうちの上下端の2個のモジュールを除く全部のモジュールと残りのモジュールとで作る2次元配列のモジュール群がCT撮像用のモジュールとして機能する。このCT撮影用の開口面積を符号22Aで示す。このパノラマ撮像用か、CT撮像用かのモジュール群の選択は、スリット23の開口面積の制御によりなされる。図4における参照符号AXdは、検出器22自身を自転(回転)させるときの中心軸である。 It should be noted that a plurality of modules arranged in a column arranged in a line on the left side in FIG. 4 function as modules for panoramic imaging. The opening area for panoramic photography is indicated by reference numeral 22B. Further, a module group of a two-dimensional array formed by all the modules except the two modules at the upper and lower ends of the left side row and the remaining modules functions as a module for CT imaging. The opening area for CT imaging is indicated by reference numeral 22A. The module group for panoramic imaging or CT imaging is selected by controlling the opening area of the slit 23. Reference numeral AXd in FIG. 4 is a central axis when the detector 22 itself rotates (rotates).
 個々の検出モジュールB1(~Bm)はX線を直接、電気パルス信号に変換する半導体材料で作成される。このため、検出器22は、半導体による直接変換方式の光子計数型X線検出器である。 Individual detection modules B1 (˜Bm) are made of a semiconductor material that directly converts X-rays into electrical pulse signals. For this reason, the detector 22 is a photon counting X-ray detector of a direct conversion method using a semiconductor.
 この検出器22は、上述したように、複数の検出モジュールB1~Bmのアレイとして形成される。各検出モジュールBmは、周知のように、X線を検出する検出回路Cp(図5参照)と、その検出回路Cpと一体に積層されたデータ計数回路51(図5参照)を備える。検出回路Cpは、検出モジュール毎に、X線を直接、電気信号に変換する半導体層と、この両面にそれぞれ積層させた荷電電極及び集電電極とを備える(図示せず)。荷電電極にX線を入射させる。荷電電極は共通の1枚の電極であり、荷電電極との間にバイアスの高電圧が印加される。半導体層及び集電電極は碁盤目状に分割され、この分割により、相互に一定の距離を置いて2次元アレイ状に配置される複数の小領域が形成される。これにより、荷電電極上に2次元状に配列された複数の、半導体セルC(図4,5参照)及び集電電極の積層体が形成される。この複数の積層体が、2次元の碁盤目状に配列された複数の画素Sを構成する。 As described above, the detector 22 is formed as an array of a plurality of detection modules B1 to Bm. Each detection module Bm includes a detection circuit Cp (see FIG. 5) for detecting X-rays and a data counting circuit 51 n (see FIG. 5) stacked together with the detection circuit Cp, as is well known. The detection circuit Cp includes, for each detection module, a semiconductor layer that directly converts X-rays into an electrical signal, and a charging electrode and a collecting electrode that are respectively stacked on both sides (not shown). X-rays are incident on the charged electrode. The charged electrode is a common electrode, and a high bias voltage is applied between the charged electrodes. The semiconductor layer and the collecting electrode are divided into a grid pattern, and by this division, a plurality of small regions are formed that are arranged in a two-dimensional array at a certain distance from each other. As a result, a plurality of stacked bodies of semiconductor cells C (see FIGS. 4 and 5) and collecting electrodes arranged in a two-dimensional manner on the charged electrode are formed. The plurality of stacked bodies to form a plurality of pixels S n arranged in a two dimensional grid pattern.
 この結果、複数の検出モジュールB1~Bmの全体によって(ただしCT撮影時の開口面積22Aによる:図4参照)、検出器22に必要な所定領域を占める複数の画素S(n=1~N)が形成される。この複数の画素Sが画素群Cpを構成する(図5参照)。 As a result, a plurality of pixels S n (n = 1 to N) occupying a predetermined area necessary for the detector 22 by the whole of the plurality of detection modules B1 to Bm (however, depending on the opening area 22A at the time of CT imaging: see FIG. 4). ) Is formed. The plurality of pixels S n constitutes a pixel group Cp (refer to FIG. 5).
 各画素Sのサイズは、例えば200μm×200μmであり、この画素サイズは、入射するX線を多数の光子の集まりとして検出可能な値に設定されている。各画素Sは、X線の各光子の入射に反応し、各光子が持つエネルギに応じた振幅の電気パルスを出力する。つまり、各画素Sは、その画素に入射するX線を直接、電気信号に変換することができる。 The size of each pixel S n is, for example, 200 [mu] m × 200 [mu] m, the pixel size is set to a detectable value X-rays incident as a set of multiple photons. Each pixel S n is responsive to incident of each photon of X-ray, and outputs an electrical pulse of amplitude corresponding to the energy possessed by the photon. That is, each pixel S n may convert the X-rays incident on that pixel directly, into electric signals.
 このため、検出器22は、入射するコーンビーム状のX線を成す光子を、検出器22の検出面を構成する画素S毎に計数して、その計数した値を反映させた電気量のデータを例えば75fpsの高いフレームレートで出力する。このデータはフレームデータとも呼ばれる。 Therefore, the detector 22, the photon constituting the cone beam-like X-rays incident, counts for each pixel S n which constitute the detection surface of the detector 22, the quantity of electricity that reflects the count value Data is output at a high frame rate of, for example, 75 fps. This data is also called frame data.
 半導体層、すなわち半導体セルCの半導体材料としては、テルル化カドミウム半導体(CdTe半導体)、カドミュームジンクテルライド半導体(CdZnTe半導体(CZT半導体))、シリコン半導体(Si半導体)、臭化タリューム(T1Br)、ヨウ化水銀などが用いられる。なお、この半導体セルの代わりに、柱状に細分化し、光学的に各柱が遮光された構造を持つシンチレータ素材と、微細なアバランシェフォトダイオードの組合せで構成した光電変換器を組み合わせたセルで構成してもよい。 As the semiconductor material of the semiconductor layer, that is, the semiconductor cell C, cadmium telluride semiconductor (CdTe semiconductor), cadmium zinc telluride semiconductor (CdZnTe semiconductor (CZT semiconductor)), silicon semiconductor (Si semiconductor), thallium bromide (T1Br) Mercury iodide or the like is used. Instead of this semiconductor cell, it is composed of a cell that combines a scintillator material that is subdivided into columns and optically shielded from each column, and a photoelectric converter composed of a combination of fine avalanche photodiodes. May be.
 このため、半導体セルCにX線が入射すると、セル内部に電荷(電子、正孔)が発生して、その電荷量に応じたパルス電流が流れる。このパルス電流は集電電極により検出される。この結果、電荷量はX線の光子のエネルギ値により変わる。このため、検出器22は、その画素S毎に光子のエネルギ値に応じた電気パルス信号を出力する。 For this reason, when X-rays enter the semiconductor cell C, charges (electrons, holes) are generated inside the cell, and a pulse current corresponding to the amount of the charge flows. This pulse current is detected by the current collecting electrode. As a result, the amount of charge varies depending on the energy value of the X-ray photons. Therefore, the detector 22 outputs an electrical pulse signal corresponding to the energy value of the photons for respective pixels S n.
 この検出器22は更に、半導体セルCのそれぞれ、すなわち、複数の画素Sそれぞれの出力側にデータ計数回路51(n=1~N)を備える。ここで、画素Sのそれぞれ、すなわち半導体セルCのそれぞれから各データ計数回路51(~51)に至る経路を、必要に応じて、収集チャンネルCN(n=1~N)と呼ぶ(図5参照)。 The detector 22 further comprises respective semiconductor cell C, that the data counting circuit 51 on the output side of each of the plurality of pixels S n n the (n = 1 ~ N). Here, each pixel S n, i.e., the path from each semiconductor cell C to the data counting circuit 51 1 (~ 51 N), optionally, referred to as acquisition channels CN n (n = 1 ~ N ) (See FIG. 5).
 なお、この半導体セルCの群の構造は、特開2000-69369号公報、特開2004-325183号公報、特開2006-101926号公報によっても知られている。 The structure of this group of semiconductor cells C is also known from Japanese Patent Application Laid-Open Nos. 2000-69369, 2004-325183, and 2006-101926.
 ところで、前述した各画素Sのサイズ(200μm×200μm)は、X線を光子(粒子)として検出することが可能な十分小さい値になっている。本実施形態において、X線をその粒子として検出可能なサイズとは、「放射線(例えばX線)粒子が同一位置又はその近傍に複数個連続して入射したときの各入射に応答した電気パルス間の重畳現象(パイルアップとも呼ばれる)の発生を実質的に無視可能な又はその量が予測可能なサイズ」であると定義される。 Incidentally, the size of each pixel S n described above (200 [mu] m × 200 [mu] m) is adapted to a sufficiently small value that is capable of detecting X-rays as photons (particles). In the present embodiment, the size capable of detecting X-rays as the particles is “between electric pulses responding to each incident when a plurality of radiation (for example, X-ray) particles are successively incident at or near the same position. The occurrence of the superposition phenomenon (also called pile-up) is defined as “a size that can be substantially ignored or whose amount is predictable”.
 しかしながら、このような画素サイズを以ってしても、重畳現象の発生を全て回避できる訳でない。2つ或いはそれ以上の電気パルスが共に同一画素において観測される場合でも、時間的に互いに分離していれば、重畳現象が起きない。これに対し、2つ或いはそれ以上の電気パルスが共に同一画素において時間的に分離し難い場合、重畳現象が起きて、2つの電気パルスが重なって波高値が高くなった1つの電気パルスとして観測される。 However, even with such a pixel size, it is not possible to avoid all occurrences of the superposition phenomenon. Even when two or more electrical pulses are both observed in the same pixel, the superposition phenomenon does not occur if they are separated from each other in time. On the other hand, when two or more electric pulses are difficult to separate in time in the same pixel, a superposition phenomenon occurs, and the two electric pulses overlap to be observed as one electric pulse having a high peak value. Is done.
 この重畳現象が発生すると、X線粒子の「入射数対実際の計数値」の特性にX線粒子の数え落とし(パイルアップカウントロスとも呼ばれる)が発生する。このため、X線検出器22に形成する画素Sのサイズは、この数え落としが発生しない又は実質的に発生しないとみなせる大きさに、又は、数え落し量が推定できる程度に設定されている。 When this superposition phenomenon occurs, X-ray particle countdown (also called pile-up count loss) occurs in the characteristic of “number of incidents versus actual count value” of X-ray particles. Therefore, the size of the pixel S n to form the X-ray detector 22, the magnitude of which can be regarded as the counting loss does not occur or does not substantially occur, or are set to an extent counting the drop amount can be estimated .
 続いて、図5を用いて、検出器22に電気的に繋がる回路を説明する。複数のデータ計数回路51(n=1~N)のそれぞれは、各半導体セルCから出力されたアナログ量の電気信号を受けるチャージアンプ52を有し、このチャージアンプ52の後段に、波形整形回路53、多段の比較器54(ここではi=1~4)、エネルギ領域振分け回路55、多段のカウンタ56(ここではi=1~4)、多段のD/A変換器57(ここではi=1~4)、ラッチ回路58、及びシリアル変換器59を備える。 Subsequently, a circuit electrically connected to the detector 22 will be described with reference to FIG. Each of the plurality of data counting circuits 51 n (n = 1 to N) includes a charge amplifier 52 that receives an electrical signal of an analog amount output from each semiconductor cell C. Circuit 53, multi-stage comparator 54 i (here i = 1 to 4), energy region distribution circuit 55, multi-stage counter 56 i (here i = 1 to 4), multi-stage D / A converter 57 i ( Here, i = 1 to 4), a latch circuit 58, and a serial converter 59 are provided.
 各チャージアンプ52は、各半導体セルSの各集電電極に接続され、X線粒子の入射に応答して集電される電荷をチャージアップして電気量のパルス信号として出力する。このチャージアンプ52の出力端は、ゲイン及びオフセットが調整可能な波形整形回路53に接続されており、検知したパルス信号の波形を、予め調整されているゲイン及びオフセットで処理して波形整形する。この波形整形回路53のゲイン及びオフセットは、半導体セルCから成る画素S毎の電荷チャージ特性に対する不均一性と各回路特性のバラツキを考慮して、キャリブレーションされる。これにより、不均一性を排除した波形整形信号の出力とそれに対する相対的な閾値の設定精度とを上げることができる。この結果、各画素Sに対応した、即ち、各収集チャンネルCNの波形整形回路53から出力された波形整形済みのパルス信号は実質的に入射するX線粒子のエネルギ値を反映した特性を有する。したがって、収集チャンネルCN間のばらつきは大幅に改善される。 Each charge amplifier 52 is connected to each current collecting electrode of each semiconductor cell S, charges up the current collected in response to the incidence of X-ray particles, and outputs it as a pulse signal of electric quantity. The output terminal of the charge amplifier 52 is connected to a waveform shaping circuit 53 whose gain and offset can be adjusted. The waveform of the detected pulse signal is processed with the previously adjusted gain and offset to shape the waveform. The gain and offset of the waveform shaping circuit 53, in consideration of the variation in non-uniformity and the circuit characteristics for charge-charge characteristic for each pixel S n of semiconductor cell C, is calibrated. As a result, it is possible to increase the output of the waveform shaping signal from which non-uniformity has been eliminated, and the relative threshold setting accuracy. As a result, corresponding to each pixel S n, i.e., the characteristics reflecting the energy value of the X-ray particle pulse signal waveform formatted output from the waveform shaping circuit 53 for each collection channel CN n is substantially incident Have. Therefore, the variation between the collection channels CN n is greatly improved.
 この波形整形回路53の出力端は、複数の比較器54~54の比較入力端にそれぞれ接続されている。この複数の比較器54~54それぞれの基準入力端には、図5に示す如くそれぞれ値が異なるアナログ量の閾値(電圧値)th(ここではi=1~4)が印加されている。これにより、1つのパルス信号と異なるアナログ量閾値th~thのそれぞれとを比較することができる。図6に、1つのX線光子の入力に応じて生起されるパルス電圧の波高値(エネルギを表す)とそれらの閾値th~thとの大小関係(th<th<th<th)模式的に示す。 The output terminal of the waveform shaping circuit 53 is connected to the comparison input terminals of the plurality of comparators 54 1 to 54 4 . As shown in FIG. 5, analog amount threshold values (voltage values) th i (here, i = 1 to 4) having different values are applied to the reference input terminals of the plurality of comparators 54 1 to 54 4, respectively. Yes. This makes it possible to compare one pulse signal with each of the different analog amount thresholds th 1 to th 4 . FIG. 6 shows the magnitude relationship (th 1 <th 2 <th 3 <threshold) between the peak value (representing energy) of the pulse voltage generated in response to the input of one X-ray photon and the threshold values th 1 to th 4. th 4 ) schematically.
 この比較の理由は、入射したX線粒子のエネルギ値が、事前に複数に分けて設定したエネルギ領域のうちのどの領域に入るのか(弁別)について調べるためである。パルス信号の波高値(つまり、入射するX線光子のエネルギ値を表す)がアナログ量閾値th~thのどの値を超えているかについて判断される。これにより、弁別されるエネルギ領域が異なる。なお、最も低いアナログ量閾値thは、通常、外乱や、半導体セルS、チャージアンプ52などの回路に起因するノイズ、或いは、画像化に必要のない低エネルギの放射線を検出しないようにするための閾値として設定される。また、閾値の数、すなわち比較器の数は、必ずしも4個に限定されず、上記アナログ量閾値thの分を含めて3個、又は、5個以上であってもよい。 The reason for this comparison is to examine which region (discrimination) the energy value of the incident X-ray particle enters among the energy regions set in advance divided into a plurality. A determination is made as to which of the analog amount threshold values th 1 to th 4 exceeds the peak value of the pulse signal (that is, the energy value of the incident X-ray photon). Thereby, the energy area | region discriminated differs. Note that the lowest analog amount threshold th 1 is usually used to prevent detection of disturbance, noise due to circuits such as the semiconductor cell S and the charge amplifier 52, or low-energy radiation that is not necessary for imaging. Is set as the threshold value. Further, the number of thresholds, i.e., the number of comparators is not necessarily limited to four, three, including the amount of the analog amount threshold th 1, or may be five or more.
 上述したアナログ量閾値th~thは、具体的には、コンソール17のキャリブレーション演算器38からインターフェース31を介してデジタル値で画素S毎、即ち収集チャンネル毎に与えられる。このため、比較器54~54それぞれの基準入力端は4つのD/A変換器57~57の出力端にそれぞれ接続されている。このD/A変換器57~57はラッチ回路58を介して閾値受信端T(~T)に接続され、この閾値受信端T(~T)がコンソール17のインターフェース31に接続されている。 Analog amount threshold th 1 ~ th 4 described above, specifically, given from the calibration computing unit 38 of the console 17 for each pixel S n in a digital value through the interface 31, i.e., for each acquisition channels. Therefore, the reference input terminals of the comparators 54 1 to 54 4 are connected to the output terminals of the four D / A converters 57 1 to 574, respectively. The D / A converter 57 1-57 4 is connected to the threshold receiving end T 1 via the latch circuits 58 (~ T N), the interface 31 of the threshold receiving end T 1 (~ T N) console 17 It is connected.
 ラッチ回路58は、撮像時に、閾値付与器41からインターフェース31及び閾値受信端T(~T)を介して与えられたデジタル量の閾値th´~th´をラッチし、対応するD/A変換器57~57にそれぞれ出力される。このため、D/A変換器57~57は指令されたアナログ量の閾値th~thを電圧量として比較器54~54それぞれに与えることができる。各収集チャンネルCNは、D/A変換器57(i=1~4)から比較器54(i=1~4)を介してカウンタ56(i=1~4)に至る1つ又は複数の回路系につながっている。この回路系を「弁別回路」DS(i=1~4)と呼ぶ。 The latch circuit 58 latches the thresholds th 1 ′ to th 4 ′ of digital quantities given from the threshold applier 41 via the interface 31 and the threshold receiving end T 1 (to T N ) at the time of imaging, and the corresponding D / are output to a converters 57 1-57 4. Therefore, the D / A converters 57 1 to 57 4 can supply the commanded analog amount thresholds th 1 to th 4 to the comparators 54 1 to 54 4 as voltage amounts, respectively. Each collection channel CN n is one from the D / A converter 57 i (i = 1 to 4) to the counter 56 i (i = 1 to 4) via the comparator 54 i (i = 1 to 4). Or it is connected to a plurality of circuit systems. This circuit system is called “discrimination circuit” DS i (i = 1 to 4).
 図7に、このアナログ量閾値th(i=1~4)に相当するエネルギ閾値TH(i=1~4)の設定例を示す。このエネルギ閾値TH(i=1~4)は勿論、離散的に設定されるとともに、ユーザが任意の値に設定可能な弁別値である。なお、図7は、X線管21の陽極材に適度な材料を用いたときのX線スペクトルを模式的に示す。横軸はX線エネルギを示すと共に、縦軸はX線光子の入射頻度を示す。この入射頻度はX線光子の計数値(カウント)又は強度を代表するファクタである。 FIG. 7 shows a setting example of the energy threshold TH i (i = 1 to 4) corresponding to the analog amount threshold th i (i = 1 to 4). This energy threshold TH i (i = 1 to 4) is of course a discrete value that is set discretely and can be set to an arbitrary value by the user. FIG. 7 schematically shows an X-ray spectrum when an appropriate material is used for the anode material of the X-ray tube 21. The horizontal axis indicates X-ray energy, and the vertical axis indicates the incidence frequency of X-ray photons. This incidence frequency is a factor representative of the count value (count) or intensity of X-ray photons.
 アナログ量閾値thは、各弁別回路DSにおいて比較器54iに与えるアナログ電圧であり、エネルギ閾値THはエネルギスペクトラムのX線エネルギ(keV)を弁別するアナログ値である。図7に示す波形は、通常に使用されている、例えば陽極材としてタングステンを用いたX線管球から曝射されるX線のエネルギの連続スペクトルを示す。なお、縦軸の計数値(カウント)は横軸のエネルギ値に相当するフォトンの発生頻度に比例する量であり、横軸のエネルギ値はX線管21の管電圧に依存する量である。このスペクトルに対して、第1のアナログ量閾値thを、X線光子数を計数不要領域(計数に意味のあるX線情報がなく、かつ回路ノイズが混在する領域)と低目の第1のエネルギ領域ERとを弁別可能なエネルギ閾値THに対応して設定する。また、第2及び第3のアナログ量閾値th、thを、第1のエネルギ閾値THより高い、第2、第3のエネルギ閾値TH,THを順に供するように設定している。さらに、第4のエネルギ閾値THはエネルギスペクトラムにおける、重畳現象が無ければX光子の計数値=0となる、X線管への印加電圧に等しいエネルギ値に設定されている。ここで、第4のエネルギ閾値THを、画素S毎に、計数値=0となるエネルギ値に合わせていることは本願の重要な特徴の一つである。 The analog amount threshold th i is an analog voltage applied to the comparator 54 i in each discrimination circuit DS i , and the energy threshold TH i is an analog value for discriminating the X-ray energy (keV) of the energy spectrum. The waveform shown in FIG. 7 shows a continuous spectrum of the energy of X-rays exposed from an X-ray tube that is normally used, for example, using tungsten as an anode material. The count value (count) on the vertical axis is an amount proportional to the photon generation frequency corresponding to the energy value on the horizontal axis, and the energy value on the horizontal axis is an amount depending on the tube voltage of the X-ray tube 21. With respect to this spectrum, the first analog quantity threshold th 1 is set as the X-ray photon count non-counting area (the area where there is no meaningful X-ray information for counting and the circuit noise is mixed) and the lower first to set corresponding to the energy region ER 1 and energy threshold value TH 1 capable discrimination of. Further, the second and third analog amount threshold values th 2 and th 3 are set so as to sequentially provide the second and third energy threshold values TH 2 and TH 3 which are higher than the first energy threshold value TH 1 . . Further, the fourth energy threshold TH 4 is set to an energy value equal to the applied voltage to the X-ray tube, in which X photon count value = 0 if there is no superposition phenomenon in the energy spectrum. Here, the fourth energy threshold TH 4, each pixel S n, it is one of the important features of the present application are in accordance with the energy value of the count value = 0.
 これにより、エネルギスペクトラムの特性や設計値に基づいた適宜な弁別点が規定され、エネルギ領域ER~ERが設定される。 As a result, appropriate discrimination points based on energy spectrum characteristics and design values are defined, and energy regions ER 1 to ER 4 are set.
 また、これらのエネルギ閾値THは、基準となる一つ以上の被写体を想定し、エネルギ領域毎の所定時間の計数値が概略一定になるように決定される。 These energy thresholds TH i are determined so that one or more subjects as a reference are assumed and the count value for a predetermined time for each energy region is substantially constant.
 このため、比較器54~54の出力端は、図5に示すように、複数のカウンタ56~56の入力端にそれぞれ接続されている。 Therefore, the output of the comparator 54 1-54 3, as shown in FIG. 5, is connected to the input ends of the plurality of counters 56 1-56 4.
 カウンタ56~56のそれぞれは、比較器54~54の出力(パルス)がオンなる度にカウントアップを行う。これにより、各カウンタ56(~56)が担当するエネルギ領域ER(~ER)に弁別されるエネルギ値以上のエネルギを持つX線光子数を一定時間毎の累積値W´(~W´)として画素S毎に計数することができる。 Each of the counters 56 1-56 4 counts up every time the output of the comparator 54 1-54 3 (pulse) is turned on. As a result, the number of X-ray photons having energy equal to or higher than the energy value discriminated into the energy region ER 1 (to ER 4 ) that each counter 56 1 (to 56 4 ) takes charge of is accumulated value W 1 ′ ( it can be counted for each pixel S n as ~ W 4 ').
 具体的には、この計数動作は、4つの比較器54~54に入力する検出電圧Vdec(光子の検出エネルギ値)と閾値th~thとの関係により決まる。つまり、検出電圧Vdec<th~thのときには、全ての比較器54~54の出力=オフとなる。すなわち、その画素Sの出力=0となる。これにより、入力エネルギの計数限界として定めたエネルギ閾値THよりも小さいノイズ成分は計数されない。このノイズ成分は、図7の計数不能領域ERxに属するエネルギ値の信号に相当する。 Specifically, this counting operation is determined by the relationship between the detection voltage V dec (detected energy value of photons) input to the four comparators 54 1 to 54 4 and the threshold values th 1 to th 4 . That is, when the detection voltage V dec <th 1 to th 4 , the outputs of all the comparators 54 1 to 54 4 are turned off. In other words, the output = 0 of the pixel S n. As a result, noise components smaller than the energy threshold TH 1 defined as the input energy counting limit are not counted. This noise component corresponds to an energy value signal belonging to the non-countable region ERx in FIG.
 しかしながら、検出電圧Vdecが最小の閾値thを超える場合(Vdec≧th)、光子数は計数される。それらの関係がVdec≧thあれば、全ての比較器54~54の出力がオンとなる。つまり、全てのカウンタ56~56の計数値W´~W´がカウントアップされる。 However, if the detection voltage V dec exceeds the minimum threshold th 1 (V dec ≧ th 1 ), the number of photons is counted. If the relationship is V dec ≧ th 1 , the outputs of all the comparators 54 1 to 54 4 are turned on. That is, the count value W 1 of all the counters 56 1 ~ 56 4 '~ W 4' is counted up.
 Vdec≧thの関係になれば、2段目以降の3つの比較器54~54の出力がオンとなる。これにより、3つのカウンタ56~56の計数値W´~W´がカウントアップされる。Vdec≧thの関係になれば、3段目及び4段目の比較器54、54の出力がオンとなる。これにより、2つのカウンタ56、56の計数値W´、W´がカウントアップされる。 When the relationship of V dec ≧ th 2 is established, the outputs of the three comparators 54 2 to 54 4 in the second and subsequent stages are turned on. Thus, the three counters 56 2-56 4 counts W 2 '~ W 4' is counted up. If the relationship of V dec ≧ th 3 is established, the outputs of the third-stage and fourth-stage comparators 54 3 and 54 4 are turned on. As a result, the count values W 3 ′ and W 4 ′ of the two counters 56 3 and 56 4 are counted up.
 さらに、Vdec≧thの関係になれば、4段目の比較器54のみの出力がオンになって、4段目のカウンタ56の計数値W´のみがカウントアップされる。この場合、その入力に関わる光子のエネルギ値はイメージングや計数には適さない、第3の高いエネルギ領域ERを超える領域ERに属するノイズ成分、外乱などである。その一方で、この計数値W´は重畳現象を起こした光子や同時に入射した光子を推定したり除外したりするための情報として使用することができる。 Furthermore, if the relationship between V dec ≧ th 4, the output of the comparator module 54 4 of the fourth stage is turned on, only the counter 56 4 count value W 4 'of the fourth stage is counted up. In this case, the energy value of the photon related to the input is a noise component belonging to the region ER 4 exceeding the third high energy region ER 3 , disturbance, etc., which is not suitable for imaging or counting. On the other hand, the count value W 4 ′ can be used as information for estimating or excluding photons that have caused a superposition phenomenon or simultaneously incident photons.
 このように本実施形態では、カウンタ56~56は、それぞれ、自己が計数担当するべきエネルギ領域ER(~ER)及びそれを超えるエネルギを持つ光子数をカウントする。このため、第1~第4のエネルギ領域ER~ERそれぞれに属するエネルギを持つX線光子数、つまり、エネルギ領域毎の求めたいX線光子数をW、W、W,Wとすると、カウンタ56~56の計数値W´、W´、W´、W´との関係は、
   W=W´-W´
   W=W´-W´
   W=W´-W´
となる。なお、W=W´は重畳現象に因る、意味の無い(つまり、X線光子が持つエネルギ領域を特定できない)情報であるので演算されない。
As described above, in the present embodiment, the counters 56 1 to 56 4 count the number of photons having energy exceeding the energy range ER 1 (to ER 4 ) to be counted by the counters 56 1 to 56 4 , respectively. Therefore, the number of X-ray photons having energy belonging to each of the first to fourth energy regions ER 1 to ER 4 , that is, the number of X-ray photons to be obtained for each energy region is expressed as W 1 , W 2 , W 3 , W 4 , the relationship between the count values W 1 ′, W 2 ′, W 3 ′, W 4 ′ of the counters 56 1 to 56 4 is
W 1 = W 1 '-W 2 '
W 2 = W 2 '-W 3 '
W 3 = W 3 '-W 4 '
It becomes. Note that W 4 = W 4 ′ is not calculated because it is meaningless information (that is, the energy region of the X-ray photon cannot be specified) due to the superposition phenomenon.
 そこで、真に求めたい計数値W~Wは、後述するデータプロセッサで上式に基づく減算処理に求める。なお、理想的には、W=W´=0である。 Therefore, the count values W 1 to W 4 that are to be truly obtained are obtained by subtraction processing based on the above equation by a data processor described later. Ideally, W 4 = W 4 ′ = 0.
 このように、本実施形態にあっては、第1~第4のエネルギ領域ER~ERそれぞれに属するX線光子数W~Wは、実際の計数値W´~W´から演算(減算)によって求める。このため、比較器54~54の出力のオン、オフの組合せから、今の事象、すなわちX線光子の入射がどのエネルギ領域ER1~ER4に属するかを解読する回路が不要になる。これにより、検出器22のデータ計数回路51に実装する回路構成が簡単化される。 Thus, in the present embodiment, X-ray photon number W 1 to W 4 belonging to each of the first through fourth energy regions ER 1 to ER 4, the actual count value W 1 '~ W 4' Is obtained by calculation (subtraction). For this reason, a circuit for deciphering which energy region ER1 to ER4 the current event, that is, the incidence of X-ray photons belongs, becomes unnecessary from the combination of turning on and off the outputs of the comparators 54 1 to 54 4 . This simplifies the circuit configuration mounted on the data counting circuit 51 n of the detector 22.
 なお、本願に係るX線光子数のエネルギ領域毎の「収集」の意味には、上述のように実際の計数値から「演算によって求める」という意味と、後述する変形例のようにエネルギ領域毎のX線光子数を直接的に「計数する」という両方の意味が含まれる。 In addition, the meaning of “collection” for each energy region of the number of X-ray photons according to the present application is the meaning of “obtaining by calculation” from the actual count value as described above, and for each energy region as in a modification example described later. Both meanings of directly “counting” the number of X-ray photons are included.
 上述したカウンタ56~56にはコンソール17の後述するコントローラからスタート・ストップ端子T2を介して起動及び停止の信号が与えられる。一定時間の計数は、カウンタ自身が有するリセット回路を使って外部から管理される。 The counter 56 1-56 4 described above start and stop signals is supplied via a start-stop terminal T2 from below to the controller of the console 17. Counting for a fixed time is managed from the outside using a reset circuit included in the counter itself.
 このようにして、リセットされるまでの一定時間の間に、複数のカウンタ56~56により、検出器22に入射したX線の光子数が、画素S毎に計数される。このX線の光子数の計数値W´(k=1~4)は、カウンタ56~56のそれぞれからデジタル量の計数値として並列に出力された後、シリアル変換器59によりシリアルフォーマットに変換される。このシリアル変換器59は残り全ての収集チャンネルのシリアル変換器59~59とシリアルに接続されている。このため、全てのデジタル量の計数値は、最後のチャンネルのシリアル変換器59からシリアルに出力され、送信端T3を介してコンソール17に送られる。 Thus, during a certain period of time until reset by a plurality of counters 56 1-56 4, the number of photons of X-rays incident on the detector 22 is counted for each pixel S n. The number of photons counted value W k of the X-ray '(k = 1 ~ 4), after being outputted from each of the counters 56 1-56 4 in parallel as the count value of the digital quantity, serial format by serial converter 59 Is converted to The serial converter 59 1 is connected to the serial converter 59 2 ~ 59 N and serial all remaining acquisition channels. Therefore, the count of all digital content is output from the last channel of the serial converter 59 N serially sent to the console 17 via the transmitting end T3.
 コンソール17では、インターフェース31がそれらの計数値を受信して後述する記憶部に格納する。 In the console 17, the interface 31 receives these count values and stores them in a storage unit to be described later.
 なお、本実施形態では、上述したN個の画素Sに対応した半導体セルC及びデータ計数回路51はASIC(Application Specific Integrated Circuit)によりCMOSで一体に構成されている。勿論、このデータ計数回路51は、半導体セルCの群とは互いに別体の回路又はデバイスとして構成してもよい。 In the present embodiment, it is integrally constructed in CMOS by the semiconductor cell C and the data counting circuit 51 n corresponding to N pixels S n described above ASIC (Application Specific Integrated Circuit). Of course, the data counting circuit 51 n may be configured as a circuit or device separate from the group of semiconductor cells C.
 またなお、上記実施形態において、複数の検出モジュールB1~Bmは、柱状に加工された複数のシンチレータを束ねたシンチレーターアレイと、前記シンチレーターアレイと光学的に接続され、当該シンチレータから入射する光を受ける受光面に複数のアバランシェフォトダイオードを実装し、かつ当該受光面の前記セルに相当する所定サイズの矩形領域毎に当該領域に属する当該アバランシェフォトダイオードをクエンチング要素で電気的に接続した構成を有するシリコンフォトマルティプライヤーと、を備えていてもよい。 In the above-described embodiment, the plurality of detection modules B1 to Bm are connected to a scintillator array in which a plurality of scintillators processed into columnar shapes are bundled, and receives light incident from the scintillator. A plurality of avalanche photodiodes are mounted on the light receiving surface, and the avalanche photodiodes belonging to the region are electrically connected by a quenching element for each rectangular region having a predetermined size corresponding to the cell on the light receiving surface. And a silicon photomultiplier.
 また、シンチレータの材料はLFS(ケイ酸ルテチウム)、GAGG:Ce(ガドリニウムアルミニウムガリウムガーネット)、LuAG:Pr(プラセオジム添加ルテチウム・アルミニウム・ガーネット)、あるいは当該LuAG:Prに同等の減衰時間、発光量、比重を有する材料であってもよい。 The material of the scintillator is LFS (lutetium silicate), GAGG: Ce (gadolinium aluminum gallium garnet), LuAG: Pr (praseodymium-added lutetium aluminum garnet), or the same decay time and light emission amount as the LuAG: Pr. It may be a material having a specific gravity.
 コンソール17は、図8に示すように、信号の入出力を担うインターフェース(I/F)31を備え、このインターフェース31にバス32を介して通信可能に接続されたコントローラ33、第1の記憶部34、データプロセッサ35、表示器36、入力器37、キャリブレーション演算器38、第2の記憶部39、ROM40A~40D、及び閾値付与器41を備えている。 As shown in FIG. 8, the console 17 includes an interface (I / F) 31 that performs input and output of signals, a controller 33 that is communicably connected to the interface 31 via a bus 32, and a first storage unit 34, a data processor 35, a display unit 36, an input unit 37, a calibration calculator 38, a second storage unit 39, ROMs 40A to 40D, and a threshold value assigner 41.
 コントローラ33は、ROM40Aに予め与えられたプログラムに沿ってX線ハイブリッド機1の駆動を制御する。この制御には、X線管21に高電圧を供給する高電圧発生装置42への指令値の送出、及び、キャリブレーション演算器38への駆動指令も含まれる。第1の記憶部34は、検出器22からインターフェース31を介して送られてきた計数値であるフレームデータ、及び、画像データを保管する。 The controller 33 controls the drive of the X-ray hybrid machine 1 according to a program given in advance to the ROM 40A. This control includes sending a command value to the high voltage generator 42 that supplies a high voltage to the X-ray tube 21 and a drive command to the calibration calculator 38. The first storage unit 34 stores frame data and image data that are count values sent from the detector 22 via the interface 31.
 データプロセッサ35は、コントローラ33の管理の下に、ROM40Bに予め与えられたプログラムに基づいて動作する。CT撮影のときには、データプロセッサ35は、その動作により、第1の記憶部34に保管されたフレームデータを所望のCT再構成法で処理してCT画像の再構成処理を行う。一方、パノラマ撮影のときには、データプロセッサ35は、その動作により、第1の記憶部34に保管されたフレームデータに、公知のシフト・アンド・アッド(shift and add)と呼ばれる演算法に基づくトモシンセシス法を実施する。これにより、被検者Pの口腔部のCT画像又はパノラマ画像が得られる。表示器36は、作成される画像の表示や、装置の動作状況を示す情報及び入力器37を介して与えられるオペレータの操作情報の表示を担う。入力器37は、オペレータが撮像に必要な情報を装置に与えるために使用される。 The data processor 35 operates based on a program given in advance to the ROM 40B under the control of the controller 33. During CT imaging, the data processor 35 performs the CT image reconstruction process by processing the frame data stored in the first storage unit 34 by a desired CT reconstruction method. On the other hand, at the time of panoramic photography, the data processor 35 operates tomosynthesis based on a known arithmetic method called “shift and add” to the frame data stored in the first storage unit 34. To implement. Thereby, a CT image or a panoramic image of the oral cavity of the subject P is obtained. The display unit 36 is responsible for displaying an image to be created, information indicating the operation status of the apparatus, and operator operation information given via the input unit 37. The input device 37 is used by an operator to give information necessary for imaging to the apparatus.
 また、キャリブレーション演算器38は、コントローラ33の管理の下に、ROM40Cに予め内蔵されているプログラムの下で動作し、データ計数回路における画素S毎のエネルギ弁別回路毎に与える、X線エネルギ弁別のためのデジタル量の閾値をキャリブレーションする。 Further, the calibration computing unit 38, under the control of the controller 33, operating under program built in advance in ROM40C, giving for each energy discriminator circuit for each pixel S n in the data counting circuit, X-rays energy Calibrate the digital quantity threshold for discrimination.
 閾値付与器41は、コントローラ33の制御の下で、撮像時に第2の記憶部39に格納されているデジタル量の閾値を画素毎に且つ弁別回路毎に呼び出して、その閾値を指令値としてインターフェース31を介して検出器22に送信する。この処理を実行するため、閾値付与器41はROM40Dに予め格納されたプログラムを実行する。 Under the control of the controller 33, the threshold value applicator 41 calls the threshold value of the digital quantity stored in the second storage unit 39 for each pixel and for each discrimination circuit at the time of imaging, and uses the threshold value as a command value as an interface. 31 to the detector 22. In order to execute this process, the threshold value assigner 41 executes a program stored in advance in the ROM 40D.
 コントローラ33、データプロセッサ35、キャリブレーション演算器38、閾値付与器41は共に、与えられたプログラムで稼動するCPU(中央処理装置)を備えている。それらのプログラムは、ROM40A~40Dのそれぞれに事前に格納されている。 The controller 33, the data processor 35, the calibration calculator 38, and the threshold value assigner 41 are all provided with a CPU (central processing unit) that operates according to a given program. Those programs are stored in advance in each of the ROMs 40A to 40D.
 本実施形態では、データプロセッサ35は、入力器37からの操作者の指令に応じて、第1の記憶部34に格納されている計数値を読み出し、この計数値を用いて画像処理、物質同定の処理、計測処理など、指令された処理を実行する。画像処理には、例えば、「パノラマ撮影」のときのトモシンセシス法に基づく歯列の断面のパノラマ画像の生成、及び、「CT撮影」のときの所望の再構成法に基づく断層像の生成がある。 In this embodiment, the data processor 35 reads the count value stored in the first storage unit 34 in response to an operator command from the input device 37, and uses this count value for image processing and substance identification. The commanded process such as the above process and the measurement process is executed. The image processing includes, for example, generation of a panoramic image of a cross section of a dentition based on a tomosynthesis method in “panoramic imaging” and generation of a tomographic image based on a desired reconstruction method in “CT imaging”. .
 また、物質同定には、ビームハードニング情報を用いた顎部を構成する複数の物質の種類や状態の同定(特定)などがある。このCT画像の再構成や物質同定の処理は本願の特徴の一つである。この特徴を表す処理は後述するが、特筆すべきは、複数の第1~第3のエネルギ領域ER~ERそれぞれに弁別された、各画素SからのX線フォトンの計数値W(~W)(収集データでもある)のセットが得られていることである。このため、従来のように、データプロセッサ35は、それらの計数値W~Wのセットに適度な高い重み付けを施し、これを相互に加算したデータをトモシンセシス法に掛けたり、CT再構成法に掛けたりすることができる。勿論、重み付けをせずに処理することもできる。その一方で、第1~第3のエネルギ領域ER~ERそれぞれに弁別された、各画素Sの計数値W(~W)のセットを領域毎にCT再構成し、この結果得られる再構成データから散布図を生成し、その散布図から物質同定を行うこともできる。 In addition, substance identification includes identification (specification) of types and states of a plurality of substances constituting the jaw using beam hardening information. This CT image reconstruction and substance identification process is one of the features of the present application. Although the process will be described below representing the features noteworthy were discriminated into a plurality of first to third energy regions ER 1 to ER 3, respectively, the count value of the X-ray photons from each pixel S n W 1 This means that a set of (˜W 3 ) (which is also collected data) is obtained. For this reason, as in the prior art, the data processor 35 applies moderately high weights to the set of the count values W 1 to W 3 and applies the data obtained by adding them to each other to the tomosynthesis method or the CT reconstruction method. Can be hung. Of course, processing can be performed without weighting. On the other hand, are discriminated in the respective first to third energy regions ER 1 to ER 3, set to CT reconstruction for each area the count value W 1 of each pixel S n (~ W 3), this result It is also possible to generate a scatter diagram from the obtained reconstruction data and to identify the substance from the scatter diagram.
 次に、本実施形態において、コントローラ33とデータプロセッサ35が協働して実行される物質の同定から3次元レンダリングまでの一連の処理を図9に基づいて説明する。 Next, in the present embodiment, a series of processes from substance identification to three-dimensional rendering executed in cooperation with the controller 33 and the data processor 35 will be described with reference to FIG.
 このX線ハイブリッド機1の駆動状態において、コントローラ33はオペレータの指示に応答して図9の処理を開始する。まず、同図、ステップS1にて、コントローラ33は、オペレータとの間でインターラクティブにCT撮影を実行するのかパノラマ撮影を実行するのか判断する。このステップにおいて「パノラマ撮影を実行する」と判断されるときには、ステップS2に移行して、公知の方法で被検者Pの顎部のパノラマ撮影を行って、例えば歯列のパノラマ画像を得る。 In the driving state of the X-ray hybrid machine 1, the controller 33 starts the process of FIG. 9 in response to an instruction from the operator. First, in step S1, the controller 33 determines whether to perform CT imaging or panoramic imaging interactively with the operator. When it is determined in this step that “perform panoramic imaging”, the process proceeds to step S2 where panoramic imaging of the jaw of the subject P is performed by a known method to obtain, for example, a panoramic image of the dentition.
 一方、ステップS1の判断が「CT撮影の実行」になるときには、コントローラ33はデータプロセッサ35と協働してステップS3以降のステップを順次実行する。 On the other hand, when the determination in step S1 is “execution of CT imaging”, the controller 33 cooperates with the data processor 35 to sequentially execute the steps after step S3.
 まず、コントローラ33はスキャン方式をオペレータとの間でインターラクティブに又はデフォルト設定に応じて決める(ステップS3)。このスキャン方式としてはフルスキャンとハーフスキャンとが用意されている。フルスキャンは、X線管21及び検出器22の対が顎部の周りを一周(360度)しながらデータを収集する方式である。これに対し、ハーフスキャンは、X線管21及び検出器22の対が顎部の周りを半周(180度)回転しながらデータを収集する方式である。 First, the controller 33 determines the scanning method interactively with the operator or according to the default setting (step S3). As this scanning method, a full scan and a half scan are prepared. The full scan is a method of collecting data while a pair of the X-ray tube 21 and the detector 22 makes a round (360 degrees) around the jaw. On the other hand, the half scan is a method of collecting data while the pair of the X-ray tube 21 and the detector 22 rotates around the jaw part by a half turn (180 degrees).
 次に、コントローラ33は、撮像空間において位置決めされている被検者Pの顎部に対してX線スキャンを指令する(ステップS4)。この指令に応答して、X線管21及び検出器22の対が顎部の周りを回転開始するとともに、指令されたスキャン方式に基づくデータ収集が開始される(ステップS5)。この回転中に、X線管21からコーンビーム状のX線が連続的に又はパルス状に曝射され、そのX線が顎部を透過する。透過したX線は検出器22により検出される。このとき、透過X線の検出器22に対する投影面の大きさは、その検出面22Aのサイズ及び形状に一致するようにスリット23の開口が制御されている。 Next, the controller 33 instructs the X-ray scan to the jaw of the subject P positioned in the imaging space (step S4). In response to this command, the pair of the X-ray tube 21 and the detector 22 starts to rotate around the jaw, and data collection based on the commanded scanning method is started (step S5). During this rotation, cone beam-shaped X-rays are continuously or pulsedly irradiated from the X-ray tube 21, and the X-rays pass through the jaw. The transmitted X-ray is detected by the detector 22. At this time, the opening of the slit 23 is controlled so that the size of the projection surface of the transmitted X-ray with respect to the detector 22 matches the size and shape of the detection surface 22A.
 この結果、前述したように、顎部における減衰の度合を反映したX線の光子の計数値が画素S毎且つ弁別回路毎に一定周期(例えば75fps)で収集される。このため、例えば360°のフルスキャンの場合であれば、例えば360°を720ステップに分割したX線フォトンの計数値から成る投影データが収集される。この投影データは、コンソール17の第1の記憶部34に順次格納される。このデータ収集が終わると、コントローラ33はスキャン、すなわちX線照射を終了させ、且つ、線管21及び検出器22のそれぞれを所定のホームポジションに戻す(ステップS6)。この結果、例えば「720ステップ×3エネルギ領域」分の投影データが収集される。 As a result, are collected in as described above, a constant count of the photons of X-rays that reflect the degree of attenuation for each and discriminator circuit for each pixel S n in the jaw period (e.g. 75fps). For this reason, for example, in the case of a full scan of 360 °, projection data including the count value of X-ray photons obtained by dividing 360 ° into 720 steps is collected. The projection data is sequentially stored in the first storage unit 34 of the console 17. When this data collection is completed, the controller 33 terminates scanning, that is, X-ray irradiation, and returns each of the tube 21 and the detector 22 to a predetermined home position (step S6). As a result, for example, projection data for “720 steps × 3 energy regions” is collected.
 データプロセッサ35は、画素S毎に前記減算を行って第1~第3のエネルギ領域ER~ERのそれぞれに属するエネルギ値を持つX線光子数を求める(ステップS7)。 Data processor 35 determines the X-ray photon number with energy values belonging to each of the first to third energy regions ER 1 to ER 3 performs the subtraction for each pixel S n (step S7).
 次いで、コントローラ33はオペレータとの間でインターラクティブに、上記の如く収集したデータを用いてCT画像を再構成するか否かを判断する(ステップS8)。CT画像を再構成すると判断された場合(ステップS8,YES)、その再構成の処理をデータプロセッサ35に指令する。 Next, the controller 33 interactively determines with the operator whether or not to reconstruct the CT image using the data collected as described above (step S8). When it is determined to reconstruct the CT image (step S8, YES), the data processor 35 is instructed to perform the reconstruction process.
 次いで、データプロセッサ35は、第1~第3のエネルギ領域ER~ERのそれぞれに弁別された、各画素Sの計数値W(~W)からなる投影データに適宜な重み付けをし(ステップS9)、重み付けされた投影データを画素S毎に相互に加算して1セットの計数値から成る投影データを形成し、その投影データを所定の再構成法(例えばFBP法)で再構成する(ステップS10)。例えば、第1のエネルギ領域ERに弁別された各画素Sの計数値Wから成る投影データにより高い(又は低い)重み付けをし、第3のエネルギ領域ERに弁別された各画素Sの計数値Wから成る投影データにより低い(又は高い)重み付けをする。これにより、より低いエネルギの透過X線又はより高いエネルギの透過X線が強調されたCT画像が生成される。この重み付けは各種の態様で実施できるし、重み付けをしないで再構成してもよい。生成されたCT画像は表示器36で表示される(ステップS11)。 Then, the data processor 35 have been discriminated to each of the first to third energy regions ER 1 to ER 3, an appropriate weighting to projection data composed of the count value W 1 (- W 3) of each pixel S n in and (step S9), and the weighted projection data is added to each other for each pixel S n to form a projection data composed of a set count value, a predetermined reconstruction method the projection data (e.g., FBP method) Reconfiguration is performed (step S10). For example, the high (or low) weighted by the projection data consisting of the count value W 1 of each pixel S n which is discriminated in the first energy area ER 1, each pixel is discriminated in the third energy regions ER 3 S a low (or high) weighted by the projection data consisting of the count value W 3 of n. As a result, a CT image in which lower-energy transmitted X-rays or higher-energy transmitted X-rays are emphasized is generated. This weighting can be implemented in various ways, and may be reconfigured without weighting. The generated CT image is displayed on the display 36 (step S11).
 一方、コントローラ33は、ステップS8でNOと判断された場合、さらにオペレータとの間でインターラクティブに、上記の如く収集したデータを用いて、顎部を構成する複数種の物質の同定を行うか否かを判断する(ステップS12)。ここでは、物質同定とは各物質の種類を特定する処理である。ステップS12でNOと判断されるときには、物質同定を行わずに一連の処理を終える。 On the other hand, if it is determined NO in step S8, the controller 33 further interactively communicates with the operator using the data collected as described above to identify a plurality of types of substances constituting the jaw. Is determined (step S12). Here, the substance identification is a process for specifying the type of each substance. When it is determined NO in step S12, the series of processing ends without performing substance identification.
 これに対し、コントローラ33が物質同定を行うと判断した場合(ステップS12,YES)、その後の再構成処理をデータプロセッサ35に指令する。これに応答し、データプロセッサ35は、第1~第3のエネルギ領域ER~ERそれぞれに弁別された、各画素Sの計数値Wから成る投影データを使って領域毎にCT再構成する(ステップS13:図10参照)。これにより、第1~第3までの3つのエネルギ領域ER~ERに対する、顎部を含む3D(ボリューム)空間の3組のCT画像IM~IMがそれぞれ再構成される。このCT画像IM~IMのデータは第1の記憶部34に読出し可能に保存される。 On the other hand, when the controller 33 determines to perform substance identification (step S12, YES), it instructs the data processor 35 to perform subsequent reconstruction processing. In response, the data processor 35, which is discriminated in each of the first to third energy regions ER 1 to ER 3, CT re for each region using the projection data consisting count W k of each pixel S n Configure (step S13: see FIG. 10). Thereby, three sets of CT images IM 1 to IM 3 in the 3D (volume) space including the jaws are reconstructed for the three energy regions ER 1 to ER 3 from the first to the third . The data of the CT images IM 1 to IM 3 are stored in the first storage unit 34 so as to be readable.
 コントローラ33はオペレータからの指令に基づいて、それら3組のCT画像IM~IMをそのまま表示するかどうかを判断する(ステップS14)。この表示が望まれている場合(ステップS14、YES)、そのCT画像IM~IMの1組又は2組以上の画像を適宜な態様で表示器36に表示させる(ステップS15)。 Based on the command from the operator, the controller 33 determines whether or not to display the three sets of CT images IM 1 to IM 3 as they are (step S14). If this display is desired (step S14, YES), one or more sets of the CT images IM 1 to IM 3 are displayed on the display 36 in an appropriate manner (step S15).
 コントローラ33が上記表示をしないと判断した場合(ステップS14、NO),さらにインターラクティブに物質同定の処理を実行するか否かを判断する(ステップS16)。この判断がなされると、散布図作成の処理はデータプロセッサ35に任される。データプロセッサ35は、3つのCT画像IM~IMのデータを第1の記憶部34から読み出し、図11に示す2次元の散布図を作成する(ステップS17)。この2次元散布図は、その一次元を成す縦軸に示す相対減衰指数RAI(Relative Attenuation Index)と、もう一次元を成す横軸に示す線質変化指数SDI(Spectrum Deformation Index)とからなる。勿論、この散布図はそれら相対減衰指数RAI及び線質変化指数SDIを含んでいればよく、他の指数を合わせた3次元又は4次元以上の散布図であってもよい。 When the controller 33 determines not to display the above (step S14, NO), it is further determined whether to execute the substance identification process interactively (step S16). When this determination is made, the scatter diagram creation process is left to the data processor 35. The data processor 35 reads the data of the three CT images IM 1 to IM 3 from the first storage unit 34, and creates a two-dimensional scatter diagram shown in FIG. 11 (step S17). This two-dimensional scatter diagram includes a relative attenuation index RAI (Relative Attenuation Index) shown on the vertical axis forming one dimension and a quality change index SDI (Spectrum Deformation Index) shown on the horizontal axis forming another dimension. Of course, this scatter diagram only needs to include the relative attenuation index RAI and the quality change index SDI, and may be a three-dimensional or four-dimensional or more scatter diagram combining other indexes.
 このうち、相対減衰指数RAIは、3次元ボリューム空間を成す各画素S(前記検出器の画素Sとは区別する)CT値に相当する指数であって、本実施形態では、画素S毎の相対減衰指数RAI=W1+W2+W3と定義される。これに対し、線質変化指数SDIは、物質固有の線吸収係数を示す指数であって、本実施形態では、画素S毎の線質変化指数SDI=W/Wと定義される。より具体的には、相対減衰指数RAIは、少なくとも2個のエネルギ帯域全ての画素値の総和に基づく量であって参照物質に対する相対的な減衰を画素S毎に表す。また、線質変化指数は、少なくとも2個のエネルギ帯域のうちの高い方のエネルギ帯域の画素値と低い方のエネルギ帯域の同一画素の画素値との間の除算に基づく画素S毎の線質の変化を示す。なお、線質変化指数SDIは、W/WやW/Wとして定義してもよい。 Among these, the relative attenuation index RAI is a index corresponding to (pixel distinguished from the S n of the detector) CT values each pixel S B forming a three-dimensional volume space, in the present embodiment, the pixel S B Each relative attenuation index RAI = W1 + W2 + W3 is defined. In contrast, the radiation quality variation index SDI, a index to a substance-specific linear absorption coefficient, in this embodiment, is defined as a radiation quality variation index SDI = W 3 / W 1 of each pixel S B. More specifically, the relative attenuation index RAI represents the relative attenuation with respect to the reference material an amount based on a sum of at least two energy bands all the pixel values for each pixel S B. The line quality change index is a line for each pixel S B based on a division between a pixel value of a higher energy band of at least two energy bands and a pixel value of the same pixel of a lower energy band. Indicates a change in quality. The quality change index SDI may be defined as W 2 / W 1 or W 3 / W 2 .
 このように画素S毎に演算される相対減衰指数RAI及び線質変化指数SDIのデータは第1の記憶部34に保管される。 Data of the thus pixel S relative attenuation index RAI and radiation quality variation index SDI is computed for each B is stored in the first storage unit 34.
 次いで、データプロセッサ35は、第1の記憶部34から相対減衰指数RAI及び線質変化指数SDIのデータを読み出し、これらのデータから2次元散布図を作成し、その散布図を表示器36に表示する(ステップS18)。この表示例を図12に示す。この2次元散布図上に、画素S毎の、相対減衰指数RAI及び線質変化指数SDIの対応点がドットで表示される。 Next, the data processor 35 reads the data of the relative attenuation index RAI and the radiation quality change index SDI from the first storage unit 34, creates a two-dimensional scatter diagram from these data, and displays the scatter diagram on the display 36. (Step S18). An example of this display is shown in FIG. The drawing the two-dimensional scatter, for each pixel S B, the corresponding point of the relative attenuation index RAI and radiation quality variation index SDI is displayed by dots.
 次いで、データプロセッサ35は、その散布図上に示されたドットの散布状況を解析して、顎部を形成している各種の物質(軟組織、歯肉、歯槽骨、皮質骨、歯牙、金属など)の種類を同定する(ステップS19)。具体的には、その散布図上のドット点の散布状況を、予め(つまり、装置毎又は装置とは無関係にシステム毎に)物質毎に、以前にCT撮影されて求められていた散布図の分布領域を示す分散テーブルからノイズを加味した分散位置を解析し、その散布特性に応じたグルーピングを行う。さらに、そのグループ化したドットの群の位置を、第1の記憶部34に予め参照データと比較し、どのグループのドット群がどの物質に対応するか否かを判定する。 Next, the data processor 35 analyzes the dispersion state of the dots shown on the scatter diagram, and various substances (soft tissue, gingiva, alveolar bone, cortical bone, tooth, metal, etc.) forming the jaw. Is identified (step S19). Specifically, the scatter diagram of the dot points on the scatter diagram is the scatter diagram previously obtained by CT imaging for each substance in advance (that is, for each device or for each system regardless of the device). A dispersion position with noise added is analyzed from a dispersion table indicating a distribution area, and grouping is performed according to the distribution characteristics. Further, the position of the group of dot groups is compared with reference data in the first storage unit 34 in advance to determine which group of dot groups corresponds to which substance.
 さらに、その判定した物質毎に例えば異なるカラーで色付けしたり、文字によるアノテーションANを付けたり、物質毎のグループ化したドット群の領域をROIで示したりするなど、ユーザへの表示データを生成する(ステップS20)。勿論、この同定結果にはノイズなどの揺らぎ成分が含まれるので、スムージングなどのノイズ軽減処理を施すことが望ましい。 Furthermore, display data to the user is generated, for example, by coloring each determined substance with a different color, adding an annotation AN with characters, or indicating a group of dot groups grouped for each substance by ROI. (Step S20). Of course, since the identification result includes fluctuation components such as noise, it is desirable to perform noise reduction processing such as smoothing.
 この後、データプロセッサ35は、その準備した表示データを表示器36に表示する(ステップS21)。この表示例を図13に示す。この例では、各物質が異なる記号、不定形のROI、及び物質名を示すアノテーションで示されている。 Thereafter, the data processor 35 displays the prepared display data on the display 36 (step S21). An example of this display is shown in FIG. In this example, each substance is indicated by a different symbol, an irregular ROI, and an annotation indicating the substance name.
 なお、この表示データは、同定された物質の種類毎に、互いに異なる表示態様で生成・表示することが好ましい。一般化して表現するならば、互いに異なる、色相、彩度、明度、及びパターンのうちの1つ又は複数の要素を組み合わせを以って生成・表示することが好ましい。このうち、異なるパターンで表示するとは、例えば、特定の物質同定した2次元領域を斜線で表示したり、境界面のみ色を付け、中を黒ドットで表示したりする、ことである。 Note that this display data is preferably generated and displayed in different display modes for each type of identified substance. If expressed in a generalized manner, it is preferable to generate and display one or a plurality of elements of hue, saturation, brightness, and pattern that are different from each other in combination. Among them, displaying with different patterns means, for example, displaying a two-dimensional region identified with a specific substance with diagonal lines, coloring only the boundary surface, and displaying the inside with black dots.
 このように、散布図を作成することによって、顎部を含む撮像対象となった3次元空間を構成する各画素Sがどの物質で構成されているかが同定されている。 Thus, by creating a scatter plot, or is composed of each pixel S B is any substance constituting the three-dimensional space becomes an imaging target comprising jaws have been identified.
 そこで、データプロセッサ35は、その同定情報を用いて実際の顎部を表す3次元形状データを作成し(ステップS22)、その作成した3次元形状データを表示器36に表示する(ステップS23)。この3次元形状データも、上述と同様に、色相、彩度、明度、及びパターンのうちの1つ又は複数の要素を組み合わせを以って生成・表示することが好ましい。この3次元形状データは、指定された物質だけの物理的な形状を示すデータであってもよい。この3次元形状データは第1の記憶部34に保存される。 Therefore, the data processor 35 creates three-dimensional shape data representing the actual jaw using the identification information (step S22), and displays the created three-dimensional shape data on the display 36 (step S23). The three-dimensional shape data is also preferably generated and displayed by combining one or more elements of hue, saturation, brightness, and pattern, as described above. The three-dimensional shape data may be data indicating a physical shape of only a designated substance. This three-dimensional shape data is stored in the first storage unit 34.
 また、この3次元形状データは、オペレータの指示に応答したコントローラ33の制御の下、印象のために外部の歯科用CAD/CAMシステムに送信される(ステップS24)。 Also, the three-dimensional shape data is transmitted to an external dental CAD / CAM system for an impression under the control of the controller 33 in response to an instruction from the operator (step S24).
 上述した実施形態において、コントローラ33によって実行される図9のステップS1~S6の処理がスキャン手段を構成し、データプロセッサ35によって実行される図9のステップS12,S13の処理が再構成手段を構成している。また、図9のステップS16~S19の処理が物質同定手段に相当し、このうち、ステップS17の処理が散布図作成手段に相当する。図9のステップS20~S23の処理が画像生成手段に相当し、このうちのステップS22の処理が3次元形状データ作成手段を成し、ステップS23の処理が3次元形状表示手段を成す。さらに、ステップS24は送信手段に相当する。さらに、データ計数回路51nとデータプロセッサ35によって実行される図9のステップS7とによって収集手段が形成される。 In the embodiment described above, the processing in steps S1 to S6 in FIG. 9 executed by the controller 33 constitutes scanning means, and the processing in steps S12 and S13 in FIG. 9 executed by the data processor 35 constitutes reconstruction means. is doing. Further, the processing of steps S16 to S19 in FIG. 9 corresponds to the substance identifying means, and among these, the processing of step S17 corresponds to the scatter diagram creating means. The processing in steps S20 to S23 in FIG. 9 corresponds to the image generation means, among which the processing in step S22 constitutes a three-dimensional shape data creation means, and the processing in step S23 constitutes a three-dimensional shape display means. Further, step S24 corresponds to transmission means. Further, a collecting means is formed by the data counting circuit 51n and the step S7 of FIG.
 以上のように、本実施形態によれば、X線フォトンに与えた3つのエネルギ領域ER~ERの夫々に対して、再構成したCT画像から散布図を作成し、この散布図に基づいて顎部を形成する物質の種類を同定できる。この同定結果を元に、顎部の各物質の3次元形状データを作成できる。 As described above, according to the present embodiment, a scatter diagram is created from the reconstructed CT image for each of the three energy regions ER 1 to ER 3 given to the X-ray photons, and based on this scatter diagram. The type of substance that forms the jaw can be identified. Based on the identification result, three-dimensional shape data of each substance in the jaw can be created.
 顎部には、X線吸収特性の異なる軟組織から硬組織まで各種の物質がある。しかしながら、3つのエネルギ領域ER1~ER3毎に再構成した3つのCT画像データ、すなわち低エネルギ領域、中エネルギ領域、及び高エネルギ領域に弁別して各別に得たX線吸収情報に基づく相対減衰指数RAI(Relative Attenuation Index)と線質変化指数SDI(Spectrum Deformation Index)とを対比することにより、顎部に在る物質をより精度高く弁別・同定することができる。 There are various substances in the jaw from soft tissue to hard tissue with different X-ray absorption characteristics. However, three CT image data reconstructed for each of the three energy regions ER1 to ER3, that is, the relative attenuation index RAI based on the X-ray absorption information obtained by discriminating into the low energy region, the medium energy region, and the high energy region. By comparing the (Relative Attenuation Index) and the quality change index SDI (Spectrum Deformation Index), it is possible to discriminate and identify substances in the jaw more accurately.
 この点を詳述すると、画素単位に、各エネルギ領域の計数値(低い方のエネルギ領域から順にW1,W2,W3とする)を求め、縦軸にW1+W2+W3の総和(この総和をRAI相対減衰指数:Relative Attenuation Indexと呼ぶ。この指数は、パノラマ画像ではタフボーンで正規化した例もあるが、CT画像の場合は水を基準とすることで、所謂、CT値の定義と同じになる。)、横軸にW3/W1(SDI線質変化指数:
Spectrum Deformation Indexと呼ぶ)にして、散布図を描くと、各物質に応じて固有の場所に物質毎に、ある打点範囲に集まる。これをクラス化し、そのクラスの中で濃度値を定義したり、カラーを割り当てすることで、物質の性質に応じて、濃度分けあるいはカラー分けされた画像を生成したりすることができる。
This point will be described in detail. The count value of each energy region (W1, W2, W3 in order from the lower energy region) is obtained for each pixel, and the sum of W1 + W2 + W3 (this sum is expressed as RAI relative attenuation index) on the vertical axis. : Relative Attenuation Index, which is an example of normalization with tough bones in panoramic images, but in the case of CT images, it is the same as the definition of the CT value by using water as a reference). W3 / W1 on the horizontal axis (SDI quality change index:
When the scatter diagram is drawn, it is gathered in a certain spot range for each substance in a unique place according to each substance. By classifying this and defining a density value in that class, or assigning a color, it is possible to generate an image classified or colored according to the nature of the substance.
 このような方法で物質をクラス分けする手法は、単にRAIのみから判断するよりも、SDIの要素が一次元加わるために、本来物質に応じてRAIが異なることを鑑みると、物質の識別の精度は向上する。もちろん、RAIはW3/W1のみならずW3/W2あるいはW2/W1であっても良い。 In this method of classifying substances, the SDI elements are added one-dimensionally rather than simply judging from RAI alone. Will improve. Of course, the RAI may be W3 / W2 or W2 / W1 as well as W3 / W1.
 このように得た非常にダイナミックレンジの広い情報から、軟組織から硬組織まで同時に最適に表示することができる。それぞれの物質に応じて独立表示したり、カラー表示を変えて、フュージョン表示したりすることも可能である。また、物質の種類が精度良く同定できることから、安定して軟組織や硬組織の3次元形状データをより精度良く得ることできる。 From the information with a very wide dynamic range thus obtained, it is possible to optimally display from soft tissue to hard tissue at the same time. It is possible to display them independently according to each substance, or to perform fusion display by changing the color display. In addition, since the type of the substance can be identified with high accuracy, the three-dimensional shape data of soft tissue and hard tissue can be stably obtained with higher accuracy.
 この3次元形状データは、歯科用のCAD/CAMシステムにとって極めて有効なスキャンデータとなる。CAD/CAMシステムは、CAD(Computer-Aided(Assisted)Design)システムとCAM(Computer-Aided(Assisted)Manufacturing)とを統合したシステムである。つまり、コンピュータグラフィックス技術を用いて歯科用の人工物を設計及び製造するシステムである。歯科用のCAD/CAMシステムの場合、歯列模型や患者の歯の計測が必要であり、この計測結果から歯列模型や患者の歯の計測3次元モデル(3次元形状データ)が構築される。 This three-dimensional shape data is extremely effective scan data for a dental CAD / CAM system. The CAD / CAM system is a system in which a CAD (Computer-Aided (Assisted) Design) system and a CAM (Computer-Aided (Assisted) Manufacturing) are integrated. That is, a system for designing and manufacturing dental artifacts using computer graphics technology. In the case of a dental CAD / CAM system, measurement of the dentition model and the patient's teeth is necessary, and a measurement model and a three-dimensional measurement model (three-dimensional shape data) of the patient's teeth are constructed from the measurement results. .
 しかし、歯科補綴では口腔内の支台歯や顎提に適合させることが必須であるため、CADの前提として対象の生体情報の形態情報だけでなく、生体の硬軟の定量情報も計測する必要がある。従来のX線CTを用いる場合、検出器のダイナミックレンジが狭く、硬組織と軟組織を同時に撮影することが難しかった。近年、口腔内を光学的にスキャンして印象する、いわゆる光学印象が多用されている。光学印象は、術者の手振れの影響を受け易く、計測対象の複雑な中空形態、歯列同士の重なった形状などの計測には、光の性質上の限界があった。また歯冠の作成では歯冠の高さを決定するには、硬組織と軟組織の奥行のある境界情報の入手が必要であるが、これも光の性質上の限界があった。 However, since it is essential for dental prosthesis to adapt to the abutment tooth and chin on the oral cavity, it is necessary to measure not only the morphological information of the target biological information but also the quantitative information on the hardness of the living body as the premise of CAD. is there. When conventional X-ray CT is used, the dynamic range of the detector is narrow, and it is difficult to image hard tissue and soft tissue simultaneously. In recent years, so-called optical impressions have been frequently used in which an impression is obtained by optically scanning the oral cavity. The optical impression is easily affected by the hand shake of the surgeon, and there is a limit on the properties of light in measuring the complicated hollow form of the measurement object, the overlapping shape of the dentition, and the like. In the creation of a crown, it is necessary to obtain boundary information with a depth of hard tissue and soft tissue in order to determine the height of the crown, which is also limited by the properties of light.
 これに対して、本実施形態によれば、光子計数型検出器22によって収集された投影データに基づいて再構成された3次元ボリュームデータから直接、顎部を構成する物質の種類が同定され、その同定結果に基づいて顎部の構造を示す3次元形状データが作成される。再構成された3次元ボリュームデータは、上述したように、軟組織から硬組織まで広いダイナミックレンジを有する画素データに基づいて作成されている。このため、口腔部の軟組織及び硬組織を示す3次元形状データの描出能も高い。つまり、精度のよい印象を行うことができる。 On the other hand, according to the present embodiment, the type of substance constituting the jaw is directly identified from the three-dimensional volume data reconstructed based on the projection data collected by the photon counting detector 22. Based on the identification result, three-dimensional shape data indicating the structure of the jaw is created. As described above, the reconstructed three-dimensional volume data is created based on pixel data having a wide dynamic range from soft tissue to hard tissue. For this reason, the drawing ability of the three-dimensional shape data indicating the soft tissue and hard tissue of the oral cavity is also high. That is, an accurate impression can be made.
 このように、歯型などを作成する印象に必要な顎部のデータを、CT撮影した3次元データから直接得ることができ、従来の光学印象に対応して、「CT印象」に必要なデータを便利に提供できる。 In this way, the jaw data necessary for the impression of creating the tooth mold can be obtained directly from the 3D data obtained by CT, and the data necessary for the “CT impression” corresponding to the conventional optical impression. Can be conveniently provided.
 また、従来、光学印象により代表されるCAD/CAMにより設計していたインプラント手術用のサージカルガイドをCT画像から作成でき、かつ硬組織のCT画像から、サージカルガイドとのフュージョンも高精度に簡単にCTスキャナのみで可能となる。このことは光学印象用の高価な光学機器の購入が不要で、CTスキャナの購入のみで、安価で短時間にサージカルガイドの提供が歯科診療所内で出来る。また、このように軟組織が安定して見える画像が得られると、従来のX線診療では得られなかった、軟組織の病変や、軟組織と硬組織の位置関係が重要視される診断にも用いることができる。さらに、支台歯形成の自動化も可能になる。 In addition, surgical guides for implant surgery that were conventionally designed by CAD / CAM represented by optical impressions can be created from CT images, and fusion with surgical guides can be easily performed with high accuracy from CT images of hard tissues. This is possible only with a CT scanner. This eliminates the need to purchase expensive optical equipment for optical impressions, and can provide a surgical guide in a dental clinic at a low cost in a short time only by purchasing a CT scanner. In addition, when an image that makes the soft tissue appear stable in this way, it can also be used for a diagnosis in which a soft tissue lesion or a positional relationship between the soft tissue and the hard tissue is important, which cannot be obtained by conventional X-ray medical care. Can do. Furthermore, it is possible to automate the preparation of abutment teeth.
 また、本実施形態では、例えば4つのエネルギ閾値の最もエネルギの高い閾値は、X線管電圧に設定し、他の3つの閾値は画像化に寄与するエネルギ情報の範囲を3等分するように設置し、最も上のエネルギ帯の情報(この情報は、エネルギ帯域がX線管電圧に相当する値以上の帯域なので、重畳現象に因る光子数の情報であり、画像化に値しない情報である)のみを使わずに3つのエネルギ帯域に分けて再構成して、軟組織や硬組織に最適化した精度の高い再構成画像を得ることもできる。 In the present embodiment, for example, the highest energy threshold of the four energy thresholds is set to the X-ray tube voltage, and the other three thresholds divide the range of energy information contributing to imaging into three equal parts. Installed and information on the uppermost energy band (This information is information on the number of photons due to the superposition phenomenon because the energy band is a band equal to or higher than the value corresponding to the X-ray tube voltage, and is not worthy of imaging. It is also possible to obtain a highly accurate reconstructed image optimized for soft tissue and hard tissue by reconstructing the image by dividing it into three energy bands without using only (some).
 さらに、本実施形態では、顎部に存在する物質の種類を同定する上で、2次元の「相対減衰指数RAI-線質変化指数SDI」から成る散布図を用いている。この散布図を用いた方が相対減衰指数RAIだけを用いた場合に比べて、物質同定の耐ノイズ性が上がり、同定精度が向上する。 Furthermore, in the present embodiment, a scatter diagram composed of a two-dimensional “relative attenuation index RAI−radiation quality change index SDI” is used to identify the type of substance present in the jaw. Compared to the case where only the relative attenuation index RAI is used, the scatter diagram is used to increase the noise resistance of the substance identification and improve the identification accuracy.
 この理由を、図14,15を用いて説明する。両図において、いま2つの物質A及び物質Bの座標がA(SDIA,RAIA),B(SDIB,RAIB)で表されたとする。つまり、物質Aの相対減衰指数RAI=RAIA、線質変化指数SDI=SDIAであり、物質Bの相対減衰指数RAI=RAIB、線質変化指数SDI=SDIBである。ただし、この座標A,Bは物質A,Bそれぞれの散布領域を代表する代表値の位置であり、この代表値は例えば最頻値の位置、中央値の位置、算術平均値の位置、又は重心位置であるとする。 The reason for this will be described with reference to FIGS. In both figures, it is assumed that the coordinates of two substances A and B are now represented by A (SDI A , RAI A ) and B (SDI B , RAI B ). That is, the relative attenuation index RAI = RAI A and the quality change index SDI = SDI A of the substance A , and the relative attenuation index RAI = RAI B and the quality change index SDI = SDI B of the substance B. However, the coordinates A and B are representative value positions representative of the scattering regions of the substances A and B. The representative values are, for example, the mode value position, the median value position, the arithmetic mean value position, or the center of gravity. Suppose that it is a position.
 図14に示す例では、座標A(SDIA,RAIA),B(SDIB,RAIB)は、線質変化指数SDIについては比較的離れており(距離LSDI)、区別がつきやすいが、相対減衰指数RAIについてはかなり接近している(距離LRAI)。この場合、
 距離LRAI=RAIA - RAIB
であるが、距離LRAIと距離LSDIとで作る対辺の距離、すなわち散布図上での座標A,B間の距離LABは、
 距離LAB={(RAIA - RAIB)+ (SDIA - SDIB)}1/2
であり、常に距離LAB>距離LRAIである。
In the example shown in FIG. 14, the coordinates A (SDI A , RAI A ) and B (SDI B , RAI B ) are relatively distant from each other with respect to the line quality change index SDI (distance L SDI ), and can be easily distinguished. The relative attenuation index RAI is very close (distance L RAI ). in this case,
Distance L RAI = RAI A -RAI B
However, the distance between opposite sides created by the distance L RAI and the distance L SDI , that is, the distance L AB between the coordinates A and B on the scatter diagram is
Distance L AB = {(RAI A -RAI B ) 2 + (SDI A -SDI B ) 2 } 1/2
And always distance L AB > distance L RAI .
 物質A,Bの散布特性は、理論的には、散布図上でそれぞれ1点で表される。しかし、実際の計測系ではフォトンノイズ、検出器の感度ムラ、機構動作精度の程度、再構成エラーなどの要因が合算したノイズの影響がある。このため、物質A,Bの各散布特性は実際には点にならずに、ある範囲(領域)に分散する。このため、物質A,Bの種類を同定する場合、相対減衰指数RAI、すなわちCT値のみを用いて同定するよりも、線質変化指数SDIも加味した散布図上で弁別する方が座標A,B間の距離LABがより大きくなるため、耐ノイズ性が向上し、したがって、同定(弁別)精度は格段に向上する。 The scattering characteristics of the substances A and B are theoretically represented by one point on the scatter diagram. However, in an actual measurement system, there is an influence of noise that includes factors such as photon noise, detector sensitivity unevenness, mechanism operation accuracy, and reconstruction error. For this reason, each scattering characteristic of the substances A and B is not actually a point but is dispersed in a certain range (region). For this reason, when identifying the types of substances A and B, it is better to discriminate them on the scatter diagram including the quality change index SDI than the relative attenuation index RAI, that is, the CT value alone. Since the distance L AB between B becomes larger, the noise resistance is improved, and therefore the identification (discrimination) accuracy is remarkably improved.
 さらに、図15の示す例では、相対減衰指数RAIについてほぼ等しく、RAIA≒RAIBであり、相対減衰指数RAIの軸上では殆ど区別がつかない。相対減衰指数RAIのみを用いて両物質A,Bを弁別しようとしても、ノイズに埋もれて困難である。しかし、本実施形態のように、線質変化指数SDIの軸を追加することで、距離LSDIの情報を参酌して両物質A,Bを弁別できる。つまり、物質A,BのX線吸収係数が酷似していても、互いに識別できることになり、同定精度が向上する。 Further, in the example shown in FIG. 15, the relative attenuation index RAI is substantially equal, and RAIA≈RAIB, which is almost indistinguishable on the axis of the relative attenuation index RAI. Even if it is attempted to discriminate between the two substances A and B using only the relative attenuation index RAI, it is difficult to be buried in noise. However, as in this embodiment, by adding the axis of the quality change index SDI, both substances A and B can be distinguished in consideration of the information of the distance LSDI. That is, even if the X-ray absorption coefficients of the substances A and B are very similar, they can be distinguished from each other, and the identification accuracy is improved.
 (変形例)
 図16を参照して、X線を検出する検出器の変形例を説明する。この変形例に係る検出器122は画素S(n=1~N)毎、すなわち収集チャンネルCN毎にデータ計数回路151を備える。このデータ計数回路151は、単独で収集手段を構成する。
(Modification)
A modification of the detector that detects X-rays will be described with reference to FIG. The detector 122 according to this modification includes a data counting circuit 151 n for each pixel Sn (n = 1 to N), that is, for each acquisition channel CN n . The data counting circuit 151 n alone constitutes a collecting means.
 このデータ計数回路151は、図16に示すように、4段の比較器51~51と4段のカウンタ56~56との間にエネルギ領域振分け回路55が配置されている。つまり、前述した実施形態のように、比較器51~51の出力がそのままカウンタ56~56にそれぞれ入力する構成とは違って、エネルギ領域振分け回路55が比較器51~51の出力のオン・オフの組合せに基づいて、各X線光子の入射に伴うエネルギがどのエネルギ領域ER~ERに属するのかを解読し、そのエネルギ値が属するエネルギ領域ER(~ER)の計数を担当しているカウンタ56(~56)にパルス信号を送る。これにより、そのパルス信号を受けたカウンタ56(~56)のみがカウントアップすることで、エネルギ領域ER(~ER)に属するエネルギ値を持つX線光子を計数する。前述した実施形態のデータ計数回路51は最終的なX線光子のエネルギ領域毎の計数値を演算により求めた(収集した)が、この変形例に係るデータ計数回路151はそれを直接、計数することができる。 The data counting circuit 151 n, as shown in FIG. 16, the energy region distribution circuit 55 is disposed between the four-stage comparator 51 1-51 4 and 4-stage counter 56 1-56 4. That is, as in the embodiment described above, comparator 51 1-51 output 4 is unlike intact counter 56 1-56 4 respectively input to the configuration, the energy region distribution circuit 55 comparator 51 1-51 4 The energy range ER 1 to ER 4 to which the energy associated with the incidence of each X-ray photon belongs is decoded, and the energy range ER 1 (to ER 4 to which the energy value belongs. ) Is sent to the counter 56 1 (˜56 4 ) that is in charge of counting. Thus, only the counter 56 1 (˜56 4 ) that has received the pulse signal counts up, thereby counting X-ray photons having energy values belonging to the energy region ER 1 (˜ER 4 ). The data counting circuit 51 n of the above-described embodiment calculates (collects) the count value for each energy region of the final X-ray photon by calculation, but the data counting circuit 151 n according to this modification directly calculates it. Can be counted.
 具体的な構成を説明する。図16に示すように、比較器54~54の出力端は、エネルギ領域振分け回路55に接続されている。このエネルギ領域振分け回路55は、複数の比較器54~54の出力、すなわち、検出したX線粒子のエネルギ値に相当するパルス電圧とアナログ量閾値th(~th)との比較結果を解読し、そのエネルギ値がどのエネルギ領域ER~ERに分類されるかという振分けを行う。 A specific configuration will be described. As shown in FIG. 16, the output terminals of the comparators 54 1 to 54 3 are connected to the energy region distribution circuit 55. This energy region distribution circuit 55 compares the output of the plurality of comparators 54 1 to 54 4 , that is, the pulse voltage corresponding to the detected energy value of the X-ray particles and the analog amount threshold th 1 (to th 4 ). And the energy range ER 1 to ER 4 is classified.
 具体的には、この振分けは、4つの比較器54~54に入力する検出電圧Vdec(光子の検出エネルギ値)と閾値th~thとの関係により決まる。つまり、検出電圧Vdec<th~thのときには、全ての比較器54~54の出力=オフとなる。すなわち、その画素Sの出力=0となる。これにより、入力エネルギの計数限界として定めたエネルギ閾値THよりも小さいノイズ成分は計数されない。このノイズ成分は、図7の計数不能領域ERxに属するエネルギ値の信号に相当する。 Specifically, this distribution is determined by the relationship between the detection voltage V dec (detected energy value of photons) input to the four comparators 54 1 to 54 4 and the threshold values th 1 to th 4 . That is, when the detection voltage V dec <th 1 to th 4 , the outputs of all the comparators 54 1 to 54 4 are turned off. In other words, the output = 0 of the pixel S n. As a result, noise components smaller than the energy threshold TH 1 defined as the input energy counting limit are not counted. This noise component corresponds to an energy value signal belonging to the non-countable region ERx in FIG.
 しかしながら、検出電圧Vdecが最小の閾値thを超える場合(Vdec≧th)、光子数は計数される。それらの関係がth<Vdec≦th(~th)であれば、1段目の比較器54のみの出力がオンとなり、その入力に関わる光子のエネルギ値は低い方のエネルギ領域ERに弁別されるものと解読される。th<Vdec≦th(~th)の関係になれば、1段目及び2段目の比較器54、54のみの出力がオンとなり、その入力に関わる光子のエネルギ値は中程度の第2のエネルギ領域ERに弁別されるもの解読される。th<Vdec≦thの関係になれば、1段目、2段目及び3段目の比較器54、54、54のみの出力がオンとなり、その入力に関わる光子のエネルギ値は高い第3のエネルギ領域ERに弁別されると解読される。さらに、th<Vdecの関係になれば、全ての比較器54~54の出力がオンになり、その入力に関わる光子のエネルギ値はイメージングや計数には適さない、第3の高いエネルギ領域ERを超える領域ERに属するノイズ成分、外乱などであると解読される。 However, if the detection voltage V dec exceeds the minimum threshold th 1 (V dec ≧ th 1 ), the number of photons is counted. If the relationship is th 1 <V dec ≦ th 2 (˜th 4 ), only the output of the first-stage comparator 54 1 is turned on, and the energy value of the photon related to the input is in the lower energy region. Decoded as ER 1 discriminated. If the relationship of th 2 <V dec ≦ th 3 (˜th 4 ) is established, the outputs of only the first-stage and second-stage comparators 54 1 and 54 2 are turned on, and the energy value of the photon related to the input is What is discriminated into the medium second energy region ER 2 is decoded. If th 3 <V dec ≦ th 4 , the outputs of only the first-stage, second-stage, and third-stage comparators 54 1 , 54 2 , 54 3 are turned on, and the photon energy associated with the input value is decrypted to be discriminated in the high third energy region ER 3. Furthermore, if the relationship of th 4 <V dec is satisfied, the outputs of all the comparators 54 1 to 54 4 are turned on, and the energy value of the photon related to the input is not suitable for imaging or counting, the third high It is deciphered that the noise component belongs to the region ER 4 exceeding the energy region ER 3 , disturbance, and the like.
 エネルギ領域振分け回路55は、上述した比較器54~54による弁別結果に応じてカウンタ56~56の何れかに弁別結果を示すパルス信号を送る。例えば、エネルギ領域ERに弁別される事象があれば、1段目のカウンタ56にパルス信号を送る。エネルギ領域ERに弁別される事象があれば、2段目のカウンタ56にパルス信号を送る。エネルギ領域ERに弁別される事象であれば、3段目のカウンタ56にパルス信号を送る。エネルギ領域ERに弁別される事象であれば、4段目のカウンタ56にパルス信号を送る。 The energy region distribution circuit 55 sends a pulse signal indicating the discrimination result to any of the counters 56 1 to 56 4 in accordance with the discrimination result by the comparators 54 1 to 54 4 described above. For example, if there is an event to be discriminated in the energy region ER 1, and sends a pulse signal to the counter 56 1 in the first stage. If there is an event to be discriminated in the energy region ER 2, it sends a pulse signal to the second-stage counter 56 2. If events are distinguished in the energy region ER 3, and sends a pulse signal to the counter 56 3 of the third stage. If events are distinguished in the energy region ER 4, it sends a pulse signal to the counter 56 4 of the fourth stage.
 なお、このノイズに相当するエネルギ領域ERに弁別されるフォトンの計数値が、後述する画像処理、物質同定の処理、各種計測処理などに不要な情報であるときには、その値は無視すればよい。これを考慮して4段目のカウンタ56を設けないようにしてもよい。 Note that when the photon count value discriminated in the energy region ER 4 corresponding to the noise is unnecessary information for image processing, substance identification processing, various measurement processing described later, the value can be ignored. . This counter 56 4 of the fourth stage may not be provided in consideration.
 この検出器122において、上述したエネルギ領域振分け回路55を除く、他の構成は前述した図5の構成と同一である。 Other configurations of the detector 122 except for the energy region distribution circuit 55 described above are the same as the configuration of FIG. 5 described above.
 このように、この検出器122によれば、エネルギ領域振分け回路55を設けたことによりエネルギ領域ER~ERに該当するイベント(X線光子の入射)を直接に計数することができる。このため、前述した減算処理を不要にできる。つまり、前述した実施形態で説明した、データプロセッサ35によって実行される図9のステップS7は不要になる。 Thus, according to this detector 122, by providing the energy region distribution circuit 55, events corresponding to the energy regions ER 1 to ER 4 (incident X-ray photons) can be directly counted. For this reason, the above-mentioned subtraction process can be made unnecessary. That is, step S7 of FIG. 9 executed by the data processor 35 described in the above embodiment is not necessary.
 さらに、本発明に係るX線CT装置の撮像対象に関する変形例を提供できる。前述した実施形態及びその変形例においては、X線CT装置の撮像対象は生体、すなわち被検体(患者の顎部)であった。つまり、撮像空間に患者の頭部を位置付けて、その顎部をCTスキャンするものであった。これに対し、この変形例では、口腔内で型を取った印象(材料)、或いは印象に石膏等の模型材料を流し込んで作った歯型模型を、撮像空間の所定位置に位置付け、その印象や歯型模型をCTスキャンするようにする。これにより、生体のCT印象と同じように歯又は歯列の3次元データを得ることができる。この場合に、型取り剤(印象材)、或いは歯型模型を作成する石膏等の材料にX線造影剤が添加される。このX線造影剤はX線に対して前述したRAI(相対減衰指数)及びSDI(線質変化指数)の少なくとも一方に関して空気との間のコントラスト差を増強する成分である。このようなX線造影剤の成分として、粉末状のヨード、バリウム、ストロンチウム、酸化チタン、酸化亜鉛などが挙げられる。これらの成分のうち、1種類又は複数種類のものが上記印象や歯型模型を作る材料に事前に添加されている。なお、CTスキャンのスライス幅はなるべく薄い値に設定される。この結果、X線造影剤によるコントラスト増強及び薄いスキャンによる分解能向上によって、歯型の内面形状や歯型の外面の輪郭形状のエッジが精度良く検出でき、より高精度な歯型用の3次元データを提供できる。 Furthermore, it is possible to provide a modification related to the imaging target of the X-ray CT apparatus according to the present invention. In the above-described embodiment and modifications thereof, the imaging target of the X-ray CT apparatus is a living body, that is, a subject (patient's jaw). That is, the patient's head is positioned in the imaging space and the jaw is CT scanned. On the other hand, in this modified example, an impression (material) taken in the oral cavity or a dental model made by pouring a model material such as gypsum into the impression is positioned at a predetermined position in the imaging space, and the impression or CT scan of the dental model. Thereby, the three-dimensional data of a tooth | gear or a dentition can be obtained similarly to CT impression of a biological body. In this case, an X-ray contrast agent is added to a material such as a mold preparation (impression material) or gypsum for creating a dental model. This X-ray contrast agent is a component that enhances the contrast difference with air with respect to at least one of the above-described RAI (relative attenuation index) and SDI (line quality change index) for X-rays. Examples of components of such an X-ray contrast agent include powdered iodine, barium, strontium, titanium oxide, and zinc oxide. Among these components, one or more types are added in advance to the material for making the impression or the tooth model. Note that the CT scan slice width is set as thin as possible. As a result, the enhancement of the contrast by the X-ray contrast agent and the improvement of the resolution by the thin scan can accurately detect the edge of the inner surface shape of the tooth mold and the contour shape of the outer surface of the tooth mold, and more accurate three-dimensional data for the tooth mold Can provide.
 なお、本発明は上述した実施形態及び変形例で示した構成に限定されるものではなく、特許請求の範囲に記載の主旨を逸脱しない限り、更に様々に変形して実施可能なものである。 Note that the present invention is not limited to the configurations shown in the above-described embodiments and modifications, and can be implemented with various modifications without departing from the spirit described in the claims.
1 X線ハイブリッド機(歯科用CT撮像及び歯科用パノラマ撮像を行うX線撮像装置)
13D 回転機構(支持手段)
17 コンソール 
15,16 アーム(支持手段)
21 X線管
22,122 検出器
23 スリット
33 コントローラ(各種のデータ処理及び制御に係る手段を機能的に実現する要素の一つ)
34 第1の記憶部
35 データプロセッサ(各種のデータ処理に係る手段を機能的に実現する要素の一つ)
36 表示器
37 入力器
40A~40D ROM
51、151 データ計数回路
54 比較器
55 エネルギ領域振分回路
56 カウンタ
57 D/A変換器
58 ラッチ回路
59 シリアル変換器
C 半導体セル
Cp 検出回路
 画素
DS 弁別回路
CN データ収集チャンネル
1 X-ray hybrid machine (X-ray imaging device for dental CT imaging and dental panoramic imaging)
13D rotating mechanism (supporting means)
17 Console
15,16 arm (support means)
21 X-ray tube 22, 122 Detector 23 Slit 33 Controller (one of the elements that functionally realizes various data processing and control means)
34 1st memory | storage part 35 Data processor (One of the elements which implement | achieves the means concerning various data processing functionally)
36 Display 37 Input device 40A to 40D ROM
51 n , 151 n Data counting circuit 54 Comparator 55 Energy domain allocating circuit 56 Counter 57 D / A converter 58 Latch circuit 59 Serial converter C Semiconductor cell Cp detection circuit S n pixel DS i discrimination circuit CN n data collection channel

Claims (18)

  1.  白色X線を曝射するX線管と、
     入射するX線の光子に応じた電気パルスを出力する画素を2次元的に配置した画素群を有する検出回路と、前記X線の連続エネルギに対してエネルギ閾値をN個(N≧3)以上与え、且つ前記各画素から出力される前記電気パルスを前記N個のエネルギ閾値により弁別するとともに、前記X線の光子数を、前記N個のエネルギ閾値で分けられ且つ当該N個のエネルギ閾値の相互間に在る「N-1」個のエネルギ帯域のそれぞれに応じて画素毎に収集する収集手段と、を有する光子計数型の検出器と、
     前記X線管と前記検出器を互いに対向させるとともに、当該X線管と当該検出器を撮像対象の周りに回転可能に支持する支持手段と、
     前記CT撮影時には前記X線管と前記検出器を前記撮像対象の周りに、指示されたスキャン法に基づいて回転させるスキャン手段と、
     前記「N-1」個のエネルギ帯域のうち少なくとも2個のエネルギ帯域それぞれに対して、前記収集手段により収集された前記X線の光子数に基づく投影データにCT(computed tomography)用の再構成処理を施して当該少なくとも2個のエネルギ帯域それぞれのCT画像を再構成する再構成手段と、
     を備えることを特徴とするX線撮像装置。
    An X-ray tube that emits white X-rays;
    A detection circuit having a pixel group in which pixels that output electric pulses corresponding to incident X-ray photons are two-dimensionally arranged, and N or more energy thresholds (N ≧ 3) with respect to the continuous energy of the X-rays And discriminating the electric pulse output from each pixel by the N energy thresholds, and the number of photons of the X-ray is divided by the N energy thresholds and the N energy thresholds A photon counting detector having collection means for collecting each pixel in accordance with each of "N-1" energy bands between each other;
    A support means for making the X-ray tube and the detector face each other, and supporting the X-ray tube and the detector around an imaging target so as to be rotatable;
    Scanning means for rotating the X-ray tube and the detector around the imaging object based on an instructed scanning method during the CT imaging;
    Reconstruction for CT (computed tomography) into projection data based on the number of photons of the X-rays collected by the collecting means for each of at least two energy bands out of the “N−1” energy bands Reconstruction means for performing processing to reconstruct a CT image of each of the at least two energy bands;
    An X-ray imaging apparatus comprising:
  2.  前記再構成手段により再構成された前記少なくとも2個のエネルギ帯域それぞれの前記画像の画素値に基づいて前記撮像対象を形成する物質の種類を同定する物質同定手段、を備えることを特徴とする請求項1に記載のX線撮像装置。 The apparatus further comprises: a substance identifying means for identifying a kind of a substance forming the imaging target based on a pixel value of the image in each of the at least two energy bands reconstructed by the reconstruction means. Item 2. The X-ray imaging apparatus according to Item 1.
  3.  前記再構成手段により再構成された前記少なくとも2個のエネルギ帯域それぞれの前記画像の画素値に基づいて前記撮像対象の構造を示す画像を生成する画像生成手段、を備えることを特徴とする請求項2に記載のX線撮像装置。 The image generation means which produces | generates the image which shows the structure of the said imaging target based on the pixel value of the said image of each of the said at least 2 energy band reconfigure | reconstructed by the said reconstruction means. 2. The X-ray imaging apparatus according to 2.
  4.  前記物質同定手段は、
     前記少なくとも2個のエネルギ帯域全ての前記画像の画素値の総和に基づく量であって参照物質に対する相対的な減衰を表す画素毎の相対減衰指数と、前記少なくとも2個のエネルギ帯域のうちの高い方のエネルギ帯域の前記画像の画素値と低い方のエネルギ帯域の前記画像の画素値との間の除算に基づく画素毎の線質変化指数とを含む2次元以上の次元を持つ散布図を作成する散布図作成手段を、備えることを特徴とする請求項2に記載のX線撮像装置。
    The substance identification means includes
    A relative attenuation index per pixel that is an amount based on the sum of pixel values of the image in all of the at least two energy bands and represents a relative attenuation with respect to a reference material, and a higher of the at least two energy bands Create a scatter diagram with two or more dimensions including a pixel quality change index for each pixel based on the division between the pixel value of the image in the lower energy band and the pixel value of the image in the lower energy band The X-ray imaging apparatus according to claim 2, further comprising: a scatter diagram creating means.
  5.  前記物質同定手段は、前記散布図から前記物質の種類名を判定するように構成されたことを特徴とする請求項4に記載のX線撮像装置。 The X-ray imaging apparatus according to claim 4, wherein the substance identification unit is configured to determine a type name of the substance from the scatter diagram.
  6.  前記画像生成手段は、
     前記散布図作成手段により作成された前記2次元散布図のデータから前記撮像対象に在って互いに質的に類似する又は同質の物質に分類した3次元形状データを作成する3次元形状データ作成手段を備えることを特徴とする請求項4に記載のX線撮像装置。
    The image generating means includes
    Three-dimensional shape data creation means for creating three-dimensional shape data classified into substances that are qualitatively similar or of the same quality in the imaging target from the data of the two-dimensional scatter chart created by the scatter diagram creation means The X-ray imaging apparatus according to claim 4, comprising:
  7.  前記撮像対象は、生体である被検者の顎部であり、
     前記画像生成手段は、
     前記3次元形状データ作成手段により作成された前記3次元形状データを前記物質の種類毎に互いに異なる、色相、彩度、明度、及びパターンのうちの1つ又は複数の組合せで表示する3次元形状表示手段を備え、
     前記物質の種類には、前記顎部の歯肉部、筋肉、舌、上顎洞内の膿を含む軟組織、歯、歯槽骨、皮質骨、並びに、金属及び/又は補綴物である硬組織の少なくとも1つが含まれる、ことを特徴とする請求項6に記載のX線撮像装置。
    The imaging target is a subject's jaw that is a living body,
    The image generating means includes
    A three-dimensional shape for displaying the three-dimensional shape data created by the three-dimensional shape data creating means in one or more combinations of hue, saturation, brightness, and pattern, which are different from each other for each type of the substance. A display means,
    The type of the substance includes at least one of gingiva of the jaw, muscle, tongue, soft tissue including pus in the maxillary sinus, tooth, alveolar bone, cortical bone, and hard tissue which is a metal and / or prosthesis. The X-ray imaging apparatus according to claim 6, further comprising:
  8.  前記3次元形状データ作成手段により作成された前記3次元形状データを外部のシステムに送信する送信手段を備えることを特徴とする請求項6に記載のX線撮像装置。 The X-ray imaging apparatus according to claim 6, further comprising a transmission unit that transmits the three-dimensional shape data created by the three-dimensional shape data creation unit to an external system.
  9.  前記検出回路は、前記X線を前記電気パルスに直接変換する半導体材料で形成され且つ前記画素毎に分割された半導体層と、この半導体層の一方の面に積層された荷電電極と、前記半導体層の他方の面に積層され且つ前記画素毎に分割された集電電極とを有し、
     前記収集手段は前記検出回路と一体の層としてのASIC(Application Specific Integrated Circuit)層として作り込まれており、
     前記半導体材料はCdTe、CZT、又はTlBrである、
    ことを特徴とする請求項1~8の何れか一項に記載のX線撮像装置。
    The detection circuit includes a semiconductor layer formed of a semiconductor material that directly converts the X-rays into the electric pulse and divided for each pixel, a charged electrode stacked on one surface of the semiconductor layer, and the semiconductor A current collecting electrode stacked on the other surface of the layer and divided for each pixel,
    The collecting means is built as an ASIC (Application Specific Integrated Circuit) layer as a layer integral with the detection circuit,
    The semiconductor material is CdTe, CZT, or TlBr.
    The X-ray imaging apparatus according to any one of claims 1 to 8, wherein
  10.  前記検出回路は、
     柱状に加工された複数のシンチレータを束ねたシンチレーターアレイと、
     前記シンチレーターアレイと光学的に接続され、当該シンチレータから入射する光を受ける受光面に複数のアバランシェフォトダイオードを実装し、かつ当該受光面のセルに相当する所定サイズの矩形領域毎に当該領域に属する当該アバランシェフォトダイオードをクエンチング要素で電気的に接続した構成を有するシリコンフォトマルティプライヤーと、を備え、
     前記収集手段は前記検出回路と一体の層としてのASIC(Application Specific Integrated Circuit)層として作り込まれており、
     前記シンチレータの材料はLFS(ケイ酸ルテチウム)、LuAG:Pr(プラセオジム添加ルテチウム・アルミニウム・ガーネット)、あるいは当該LuAG:Pr相当の減衰時間、発光量、比重を有する材料である、
     ことを特徴とする請求項1~8の何れか一項に記載のX線撮像装置。
    The detection circuit includes:
    A scintillator array in which a plurality of scintillators processed into columnar shapes are bundled;
    A plurality of avalanche photodiodes are mounted on a light receiving surface that is optically connected to the scintillator array and receives light incident from the scintillator, and each rectangular region having a predetermined size corresponding to a cell on the light receiving surface belongs to the region. A silicon photomultiplier having a configuration in which the avalanche photodiode is electrically connected by a quenching element;
    The collecting means is built as an ASIC (Application Specific Integrated Circuit) layer as a layer integral with the detection circuit,
    The material of the scintillator is LFS (lutetium silicate), LuAG: Pr (praseodymium-added lutetium / aluminum / garnet), or a material having decay time, light emission amount and specific gravity equivalent to the LuAG: Pr,
    The X-ray imaging apparatus according to any one of claims 1 to 8, wherein
  11.  前記N個のエネルギ閾値のうちの最も高い閾値は、前記X線光子のエネルギ値の所望上限値に設定されている、ことを特徴とする請求項1~10の何れか一項に記載のX線撮像装置。 The X value according to any one of claims 1 to 10, wherein the highest threshold value among the N energy threshold values is set to a desired upper limit value of the energy value of the X-ray photon. Line imaging device.
  12.  前記所望上限値は、前記X線管の管電圧に相当する値を中心とする所望のエネルギ範囲に属する値に設定されていることを特徴とする請求項11に記載のX線撮像装置。 12. The X-ray imaging apparatus according to claim 11, wherein the desired upper limit value is set to a value belonging to a desired energy range centered on a value corresponding to a tube voltage of the X-ray tube.
  13.  前記所望上限値に対する所望エネルギ範囲は、前記N個のエネルギ閾値のうちの最も低い閾値をTHとしたとき、-TH/2<所望上限値<+TH/2あることを特徴とする請求項12に記載のX線撮像装置。 Desired energy range for the desired upper limit, when said lowest threshold value of the N energy threshold was set to TH 1, wherein, characterized in that there -TH 1/2 <a desired upper limit <+ TH 1/2 Item 13. The X-ray imaging apparatus according to Item 12.
  14.  前記検出回路及び前記収集手段は、前記画素を2次元に配置した所定サイズのモジュールを複数個、相互に隙間を空けて2次元状に配置したモジュールアレイとして形成されたことを特徴とする請求項1~13の何れか一項に記載のX線撮像装置。 The detection circuit and the collecting means are formed as a module array in which a plurality of modules of a predetermined size in which the pixels are two-dimensionally arranged are arranged two-dimensionally with a gap between each other. 14. The X-ray imaging apparatus according to any one of 1 to 13.
  15.  前記支持手段は、前記X線撮像装置とは別体である歯科用チェアに座った又は横たわった被検者の顎部が前記X線管及び前記検出器の間の撮像空間に位置可能なように当該X線管及び当該検出器を支持可能になっていることを特徴とする請求項6の何れか一項に記載のX線撮像装置。 The support means is configured such that a jaw portion of a subject sitting or lying on a dental chair separate from the X-ray imaging apparatus can be positioned in an imaging space between the X-ray tube and the detector. The X-ray imaging apparatus according to claim 6, wherein the X-ray tube and the detector can be supported.
  16.  前記検出器の前記複数のモジュールのうちの一部は、前記CT撮影に加えて、被検者の顎部のパノラマ画像に使用可能に構成されていることを特徴とする請求項14に記載のX線撮像装置。 The part of the plurality of modules of the detector can be used for a panoramic image of a subject's jaw in addition to the CT imaging. X-ray imaging device.
  17.  前記撮像対象は、生体である被検者の口腔内で型を取った印象、又は当該印象から作られた歯型模型であって、当該印象又は当該歯型模型を形成する材料に事前にX線造影剤が添加されており、
     前記X線造影剤は、少なくともヨード、バリウム、ストロンチウム、酸化チタン、又は酸化亜鉛の成分を含むことを特徴とする請求項1に記載のX線撮像装置。
    The imaging object is an impression taken in the oral cavity of a subject who is a living body, or a dental model made from the impression, and X is previously applied to a material forming the impression or the dental model. A line contrast agent is added,
    The X-ray imaging apparatus according to claim 1, wherein the X-ray contrast medium includes at least a component of iodine, barium, strontium, titanium oxide, or zinc oxide.
  18.  白色X線を曝射するX線管と、
     入射するX線の光子に応じた電気パルスを出力する画素を2次元的に配置した画素群を有する検出回路と、前記X線の光子数を画素毎に収集する収集手段と、を有する光子計数型の検出器と、
     前記X線管と前記検出器を互いに対向させるとともに、CT撮影時には当該X線管と当該検出器を撮像対象の周りに回転可能に支持する支持手段と、
     前記CT撮影時には前記X線管と前記検出器を前記撮像対象の周りに、指示されたスキャン法に基づいて回転させるスキャン手段と、
    を備えたX線撮像装置におけるX線撮像方法において、
     前記収集手段に前記X線の連続エネルギに対してエネルギ閾値をN個(N≧3)以上与えた状態で前記CT撮像を行って、前記各画素から出力される前記電気パルスを前記収集手段により前記N個のエネルギ閾値で弁別させ、前記X線の光子数を、前記N個のエネルギ閾値で分けられ且つ当該N個のエネルギ閾値の相互間に在る「N-1」個のエネルギ帯域のそれぞれに応じて画素毎に収集し、
     前記「N-1」個のエネルギ帯域のうち少なくとも2個のエネルギ帯域それぞれに対して、前記収集手段により収集された前記X線の光子数に基づく投影データにCT(computed tomography)用の再構成処理を施して当該少なくとも2個のエネルギ帯域それぞれのCT画像を再構成することを特徴とするX線撮像方法。
    An X-ray tube that emits white X-rays;
    Photon counting having a detection circuit having a pixel group in which pixels that output electric pulses corresponding to incident X-ray photons are two-dimensionally arranged, and collecting means for collecting the number of X-ray photons for each pixel A mold detector;
    The X-ray tube and the detector are opposed to each other, and support means for rotatably supporting the X-ray tube and the detector around the imaging target during CT imaging,
    Scanning means for rotating the X-ray tube and the detector around the imaging object based on an instructed scanning method during the CT imaging;
    In an X-ray imaging method in an X-ray imaging apparatus comprising:
    The CT imaging is performed in a state where N energy thresholds (N ≧ 3) or more are given to the collecting means with respect to the continuous energy of the X-rays, and the electric pulses output from the pixels are collected by the collecting means. Discriminating by the N energy thresholds, the number of photons of the X-ray is divided by the N energy thresholds and “N−1” energy bands between the N energy thresholds. Collect for each pixel according to each,
    Reconstruction for CT (computed tomography) into projection data based on the number of photons of the X-rays collected by the collecting means for each of at least two energy bands out of the “N−1” energy bands An X-ray imaging method, comprising: performing processing to reconstruct a CT image of each of the at least two energy bands.
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