[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

WO2014195861A3 - Preparation of ticagrelor - Google Patents

Preparation of ticagrelor Download PDF

Info

Publication number
WO2014195861A3
WO2014195861A3 PCT/IB2014/061912 IB2014061912W WO2014195861A3 WO 2014195861 A3 WO2014195861 A3 WO 2014195861A3 IB 2014061912 W IB2014061912 W IB 2014061912W WO 2014195861 A3 WO2014195861 A3 WO 2014195861A3
Authority
WO
WIPO (PCT)
Prior art keywords
ticagrelor
preparation
intermediates
processes
present application
Prior art date
Application number
PCT/IB2014/061912
Other languages
French (fr)
Other versions
WO2014195861A2 (en
Inventor
Raghupathi Reddy Anumula
Yakambram Bojja
Sreenivasulu Kurella
Veerender Murki
Ravi Ram Chandrasekhar Elati
Venkata Annapurna Sasikala Cheemalapati
Ugandar Reddy INUGALA
Thirupathi BALUGU
Subba Reddy Peddireddy
Kavitha Charagondla
Original Assignee
Dr. Reddy’S Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Reddy’S Laboratories Limited filed Critical Dr. Reddy’S Laboratories Limited
Priority to EP14807111.1A priority Critical patent/EP3004113A2/en
Publication of WO2014195861A2 publication Critical patent/WO2014195861A2/en
Publication of WO2014195861A3 publication Critical patent/WO2014195861A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Ceramic Products (AREA)

Abstract

The present application relate to processes for preparing Ticagrelor and its intermediates.
PCT/IB2014/061912 2013-06-04 2014-06-03 Preparation of ticagrelor WO2014195861A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP14807111.1A EP3004113A2 (en) 2013-06-04 2014-06-03 Preparation of ticagrelor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2434/CHE/2013 2013-06-04
IN2434CH2013 2013-06-04

Publications (2)

Publication Number Publication Date
WO2014195861A2 WO2014195861A2 (en) 2014-12-11
WO2014195861A3 true WO2014195861A3 (en) 2015-04-02

Family

ID=52008665

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/061912 WO2014195861A2 (en) 2013-06-04 2014-06-03 Preparation of ticagrelor

Country Status (2)

Country Link
EP (1) EP3004113A2 (en)
WO (1) WO2014195861A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI229674B (en) 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
US10017515B2 (en) * 2014-08-11 2018-07-10 Sun Pharmaceutical Industries Limited Stable amorphous ticagrelor and a process for its preparation
WO2016030704A1 (en) * 2014-08-30 2016-03-03 Cipla Limited Solid form of intermediate of ticagrelor
CN110183436A (en) * 2019-06-21 2019-08-30 南通常佑药业科技有限公司 A kind of preparation method of armorphous Ticagrelor
CN110684019B (en) * 2019-10-29 2020-08-18 株洲千金药业股份有限公司 Preparation method of ticagrelor intermediate oxide impurity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030148888A1 (en) * 2000-06-02 2003-08-07 Ulf Larsson Novel triazolo pyrimidine compounds
US7265124B2 (en) * 2000-06-02 2007-09-04 Astrazeneca Ab Cristalline and amorphous form of a triazolo (4,5-D) pyridimine compound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030148888A1 (en) * 2000-06-02 2003-08-07 Ulf Larsson Novel triazolo pyrimidine compounds
US7265124B2 (en) * 2000-06-02 2007-09-04 Astrazeneca Ab Cristalline and amorphous form of a triazolo (4,5-D) pyridimine compound

Also Published As

Publication number Publication date
EP3004113A2 (en) 2016-04-13
WO2014195861A2 (en) 2014-12-11

Similar Documents

Publication Publication Date Title
EP3060041A4 (en) Prostacyclin compounds, compositions and methods of use thereof
EP2970091A4 (en) Solid forms of treprostinil
EP3021843A4 (en) Anti-viral compounds, pharmaceutical compositions, and methods of use thereof
EP2998299A4 (en) Preparation method of azoxystrobin
EP2999708A4 (en) Processes for the preparation of dehydroepiandrosterone and its intermediates
WO2014147640A3 (en) Process for the preparation of anagliptin
IL241758B (en) Preparation of pyrimidine intermediates useful for the manufacture of macitentan
EP3055281A4 (en) Preparation of hydroxy-benzylbenzene derivatives
EP2971029C0 (en) Preparation of malto-oligosaccharides
EP3049079A4 (en) Solid forms of ceftolozane
HK1213882A1 (en) Process and intermediates for the preparation of pregabalin
IL244755A0 (en) L process for the preparation of xanthohumol
HK1202533A1 (en) Intermediates of ticagrelor and the preparation methods and for the preparation of ticagrelor
WO2014195861A3 (en) Preparation of ticagrelor
EP3013848A4 (en) Process for the preparation of abiraterone and intermediates thereof
EP3016935A4 (en) Process for the preparation of intermediate of dolutegravir
EP3068770A4 (en) Processes for the preparation of pyrimidinylcyclopentane compounds
EP3060546A4 (en) Processes for the preparation of unsaturated esters
EP3045440A4 (en) Method for the preparation of trichloromethyl-group-substituted benzene
EP3027622B8 (en) Process for the preparation of oxymorphone
EP2984055A4 (en) Preparation of surfactants via cross-metathesis
HK1217670A1 (en) Formulations of albu-bche, preparation and uses thereof albu-bche
EP3056491A4 (en) Synthetic intermediate of maxacalcitol, preparation method therefor and use thereof
WO2014145302A3 (en) Synthesis of ent-progesterone and intermediates thereof
EP3024440A4 (en) Formulation of metaxalone

Legal Events

Date Code Title Description
REEP Request for entry into the european phase

Ref document number: 2014807111

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2014807111

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14807111

Country of ref document: EP

Kind code of ref document: A2