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WO2013093514A3 - Vaccines - peptides - Google Patents

Vaccines - peptides Download PDF

Info

Publication number
WO2013093514A3
WO2013093514A3 PCT/GB2012/053255 GB2012053255W WO2013093514A3 WO 2013093514 A3 WO2013093514 A3 WO 2013093514A3 GB 2012053255 W GB2012053255 W GB 2012053255W WO 2013093514 A3 WO2013093514 A3 WO 2013093514A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
influenza
vaccines
derived
cell immunity
Prior art date
Application number
PCT/GB2012/053255
Other languages
French (fr)
Other versions
WO2013093514A2 (en
Inventor
Robert Lambkin-Williams
John Sidney Oxford
Thomas Wilkinson
Chris Li
Anthony Gilbert
Andrew Mcmichael
Xiao-Ning Xu
Original Assignee
Retroscreen Virology Ltd
University Of Southampton
The Chancellor, Masters And Scholars Of The University Of Oxford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1122299.9A external-priority patent/GB201122299D0/en
Application filed by Retroscreen Virology Ltd, University Of Southampton, The Chancellor, Masters And Scholars Of The University Of Oxford filed Critical Retroscreen Virology Ltd
Publication of WO2013093514A2 publication Critical patent/WO2013093514A2/en
Publication of WO2013093514A3 publication Critical patent/WO2013093514A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention provides influenza peptide antigens which may be used to induce T cell responses, and not only to the particular influenza strain from which peptide antigen was derived, but also to peptides derived from other influenza strains. These peptides, and vaccines comprising these peptides, are useful in inducing T cell immunity to influenza and advantageously the T cell immunity is to more than one type of influenza.
PCT/GB2012/053255 2011-12-23 2012-12-21 Vaccines - peptides WO2013093514A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201113336658A 2011-12-23 2011-12-23
US13/336,658 2011-12-23
GB1122299.9 2011-12-23
GBGB1122299.9A GB201122299D0 (en) 2011-12-23 2011-12-23 Vaccines-peptides

Publications (2)

Publication Number Publication Date
WO2013093514A2 WO2013093514A2 (en) 2013-06-27
WO2013093514A3 true WO2013093514A3 (en) 2013-08-15

Family

ID=47561656

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2012/053255 WO2013093514A2 (en) 2011-12-23 2012-12-21 Vaccines - peptides

Country Status (1)

Country Link
WO (1) WO2013093514A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7146926B2 (en) 2017-09-29 2022-10-04 ヴァクディアグン バイオテクノロジー カンパニー リミテッド Fusion peptide of CD4 helper T cell epitope and its vaccine

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015033137A1 (en) 2013-09-04 2015-03-12 Imperial Innovations Limited Biological methods and materials for use therein

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007091030A2 (en) * 2006-02-07 2007-08-16 Peptcell Limited Peptide sequences and compositions
WO2008039267A2 (en) * 2006-07-21 2008-04-03 Pharmexa Inc. Inducing cellular immune responses to influenza virus using peptide and nucleic acid compositions
WO2009027688A1 (en) * 2007-08-31 2009-03-05 Immune Targeting Systems (Its) Ltd Influenza antigen delivery vectors and constructs
US20100285050A1 (en) * 2007-10-05 2010-11-11 Isis Innovation Limited Compositions and Methods

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007091030A2 (en) * 2006-02-07 2007-08-16 Peptcell Limited Peptide sequences and compositions
WO2008039267A2 (en) * 2006-07-21 2008-04-03 Pharmexa Inc. Inducing cellular immune responses to influenza virus using peptide and nucleic acid compositions
WO2009027688A1 (en) * 2007-08-31 2009-03-05 Immune Targeting Systems (Its) Ltd Influenza antigen delivery vectors and constructs
US20100285050A1 (en) * 2007-10-05 2010-11-11 Isis Innovation Limited Compositions and Methods

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7146926B2 (en) 2017-09-29 2022-10-04 ヴァクディアグン バイオテクノロジー カンパニー リミテッド Fusion peptide of CD4 helper T cell epitope and its vaccine

Also Published As

Publication number Publication date
WO2013093514A2 (en) 2013-06-27

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