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WO2011106556A3 - Systems and methods for adaptive recursive sequencing - Google Patents

Systems and methods for adaptive recursive sequencing Download PDF

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Publication number
WO2011106556A3
WO2011106556A3 PCT/US2011/026115 US2011026115W WO2011106556A3 WO 2011106556 A3 WO2011106556 A3 WO 2011106556A3 US 2011026115 W US2011026115 W US 2011026115W WO 2011106556 A3 WO2011106556 A3 WO 2011106556A3
Authority
WO
WIPO (PCT)
Prior art keywords
sequencing
reaction chamber
component
detection component
systems
Prior art date
Application number
PCT/US2011/026115
Other languages
French (fr)
Other versions
WO2011106556A2 (en
Inventor
Charles W. Tweedy
W. Michael Lafferty
Peter B. Vander Horn
Original Assignee
Life Technologies Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corporation filed Critical Life Technologies Corporation
Publication of WO2011106556A2 publication Critical patent/WO2011106556A2/en
Publication of WO2011106556A3 publication Critical patent/WO2011106556A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A recursive sequencing system having a sequencing reaction chamber, a detection component, a sequencing analytics component and a sequencing attribute controller is disclosed. The sequencing reaction chamber receives an array with at least one immobilized nucleic acid target. The detection component is interfaced to the sequencing reaction chamber and detects incorporation of one or more fluorescent labeled nucleotides into the nucleic acid targets. The sequencing analytics component is in communication with the detection component. The sequencing attribute controller is in communication with the sequencing reaction chamber, the detection component and the sequencing analytics component. The sequencing attribute controller controls one or more sequencing attributes of the recursive sequencing system.
PCT/US2011/026115 2010-02-24 2011-02-24 Systems and methods for adaptive recursive sequencing WO2011106556A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30774710P 2010-02-24 2010-02-24
US61/307,747 2010-02-24

Publications (2)

Publication Number Publication Date
WO2011106556A2 WO2011106556A2 (en) 2011-09-01
WO2011106556A3 true WO2011106556A3 (en) 2012-01-19

Family

ID=44507567

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/026115 WO2011106556A2 (en) 2010-02-24 2011-02-24 Systems and methods for adaptive recursive sequencing

Country Status (1)

Country Link
WO (1) WO2011106556A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9184099B2 (en) 2010-10-04 2015-11-10 The Board Of Trustees Of The Leland Stanford Junior University Biosensor devices, systems and methods therefor
US9399217B2 (en) 2010-10-04 2016-07-26 Genapsys, Inc. Chamber free nanoreactor system
MX344363B (en) 2010-10-04 2016-12-14 Genapsys Inc * Systems and methods for automated reusable parallel biological reactions.
US9926596B2 (en) 2011-05-27 2018-03-27 Genapsys, Inc. Systems and methods for genetic and biological analysis
CN106591103B (en) 2011-12-01 2021-06-04 吉纳普赛斯股份有限公司 System and method for efficient electronic sequencing and detection
CA2896879C (en) 2013-03-15 2020-09-22 Genapsys, Inc. Systems and methods for biological analysis
US10125393B2 (en) 2013-12-11 2018-11-13 Genapsys, Inc. Systems and methods for biological analysis and computation
US9822401B2 (en) 2014-04-18 2017-11-21 Genapsys, Inc. Methods and systems for nucleic acid amplification
CN109790575A (en) 2016-07-20 2019-05-21 吉纳普赛斯股份有限公司 System and method for nucleic acid sequencing
SG11202002516WA (en) 2017-09-21 2020-04-29 Genapsys Inc Systems and methods for nucleic acid sequencing

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060210967A1 (en) * 2004-07-02 2006-09-21 Agan Brian K Re-sequencing pathogen microarray
US7144699B2 (en) * 1997-03-20 2006-12-05 Affymetrix, Inc. Iterative resequencing
US20080233575A1 (en) * 2006-04-14 2008-09-25 Helicos Biosciences Corporation Methods for increasing accuracy of nucleic scid sequencing

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7144699B2 (en) * 1997-03-20 2006-12-05 Affymetrix, Inc. Iterative resequencing
US20060210967A1 (en) * 2004-07-02 2006-09-21 Agan Brian K Re-sequencing pathogen microarray
US20080233575A1 (en) * 2006-04-14 2008-09-25 Helicos Biosciences Corporation Methods for increasing accuracy of nucleic scid sequencing

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JIANBIAO ZHENG ET AL.: "High-throughput, high-accuracy array-based resequencing.", PNAS., vol. 106, no. 16, 2009, pages 6712 - 6717 *
MARK J. RIEDER ET AL.: "Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome.", NUCLEIC ACIDS RESEARCH, vol. 26, no. 4, 1998, pages 967 - 973 *

Also Published As

Publication number Publication date
WO2011106556A2 (en) 2011-09-01

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