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WO2011159537A3 - Method and device for analyte detection - Google Patents

Method and device for analyte detection Download PDF

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Publication number
WO2011159537A3
WO2011159537A3 PCT/US2011/039629 US2011039629W WO2011159537A3 WO 2011159537 A3 WO2011159537 A3 WO 2011159537A3 US 2011039629 W US2011039629 W US 2011039629W WO 2011159537 A3 WO2011159537 A3 WO 2011159537A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte detection
combining
lateral
point
provides
Prior art date
Application number
PCT/US2011/039629
Other languages
French (fr)
Other versions
WO2011159537A2 (en
Inventor
Daniel T. Kamei
Benjamin M. Wu
Foad Mashayekhi
Yin To Chiu
Alexander Le
Felix C. Chao
Brian Q. Pham
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2011159537A2 publication Critical patent/WO2011159537A2/en
Publication of WO2011159537A3 publication Critical patent/WO2011159537A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention provides a method and a point-of-care device for detecting analytes by combining a complex fluid system with the lateral-flow immunoassay.
PCT/US2011/039629 2010-06-15 2011-06-08 Method and device for analyte detection WO2011159537A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35494010P 2010-06-15 2010-06-15
US61/354,940 2010-06-15

Publications (2)

Publication Number Publication Date
WO2011159537A2 WO2011159537A2 (en) 2011-12-22
WO2011159537A3 true WO2011159537A3 (en) 2012-05-31

Family

ID=45348796

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/039629 WO2011159537A2 (en) 2010-06-15 2011-06-08 Method and device for analyte detection

Country Status (1)

Country Link
WO (1) WO2011159537A2 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
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CN102662015B (en) * 2012-04-12 2013-11-20 湖南师范大学 Biological sample purification method based on inorganic salt promoted phase transition and separation of nano-gold
JP6216926B2 (en) 2012-08-21 2017-10-25 ヤンセン ファーマシューティカ エヌ．ベー． Antibodies against olanzapine and uses thereof
CN110054694B (en) * 2012-08-21 2024-02-20 詹森药业有限公司 Antibodies to aripiprazole hapten and uses thereof
EP3663316A1 (en) 2012-08-21 2020-06-10 Janssen Pharmaceutica NV Antibodies to aripiprazole and use thereof
PL2888234T3 (en) 2012-08-21 2018-07-31 Janssen Pharmaceutica Nv Haptens of aripiprazole and their use in immunoassays
AU2013305938B2 (en) 2012-08-21 2017-08-17 Saladax Biomedical Inc. Antibodies to paliperidone haptens and use thereof
ES2822004T3 (en) 2012-08-21 2021-04-28 Janssen Pharmaceutica Nv Quetiapine Antibodies and Their Use
US20140057303A1 (en) 2012-08-21 2014-02-27 Janssen Pharmaceutica Nv Antibodies to Olanzapine Haptens and Use Thereof
WO2014031630A2 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to paliperidone and use thereof
PT3385284T (en) * 2012-08-21 2020-05-20 Janssen Pharmaceutica Nv Antibodies to quetiapine haptens and use thereof
PT2888593T (en) 2012-08-21 2018-12-12 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof
CN108517014A (en) 2012-08-21 2018-09-11 詹森药业有限公司 The antibody and application thereof of Risperidone haptens
CN103675264B (en) * 2013-12-05 2015-08-19 美艾利尔（上海）诊断产品有限公司 A kind of colloidal gold film for detecting antibody on sensitization nitrocellulose filter and its preparation method and application
WO2015134938A1 (en) * 2014-03-07 2015-09-11 The Regents Of The University Of California Devices for integrating analyte extraction, concentration and detection
CN104678093A (en) * 2015-03-20 2015-06-03 上海理工大学 Preparation method of immobilized anti-clenbuterol hydrochloride monoclonal antibody
EP3345001A4 (en) 2015-09-04 2019-07-17 The Regents of the University of California Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications
JP6949025B2 (en) 2015-12-17 2021-10-13 ヤンセン ファーマシューティカ エヌ．ベー． Antibodies to risperidone and its use
CN108368180B (en) 2015-12-17 2022-07-26 詹森药业有限公司 Antibodies to quetiapine and uses thereof
KR102592388B1 (en) * 2016-06-09 2023-10-20 더 리전트 오브 더 유니버시티 오브 캘리포니아 A single platform for biomarker enrichment and signal amplification for use in paper-based immunoassays, and for extraction, concentration and amplification of DNA.
WO2018039139A1 (en) 2016-08-22 2018-03-01 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
WO2018183211A1 (en) 2017-03-27 2018-10-04 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of csf leaks
EP3586129B1 (en) * 2017-03-28 2023-07-12 Phase Scientific International, Ltd. Method for accurate diagnosis of a disease targeting biomarkers in liquid biopsy
TW201840854A (en) * 2017-03-28 2018-11-16 彥燾 招 Method and device for accurate diagnosis of dental diseases
EP3635400A4 (en) * 2017-05-31 2021-02-24 The Regents of The University of California Single-step atps enhanced lfa diagnostic design
EP4385601A3 (en) 2017-06-01 2024-08-14 Phase Diagnostics, Inc. Phase separation behavior modifying agents for aqueous two-phase separation within porous material
US11609232B2 (en) 2017-09-01 2023-03-21 Phase Diagnostics, Inc. Method and device of using aqueous two-phase systems (ATPS) for enhancing diagnostics for sexually transmitted infections
CN117448315A (en) 2017-09-18 2024-01-26 相达生物科技国际有限公司 Method for separating, purifying and/or concentrating short-chain nucleic acid fragments using aqueous two-phase system
US12043826B2 (en) 2018-01-19 2024-07-23 Phase Scientific International, Ltd. Spontaneous nucleic acid purification and concentration in a single step
US11479765B2 (en) 2018-01-19 2022-10-25 Phase Scientific International, Ltd. Method of isolating exosomes using encapsulation and aqueous micellar system
EP3740588A4 (en) 2018-01-19 2021-10-20 Phase Scientific International, Ltd. Method for isolating and purifying nucleic acids using a solid-liquid phase system
WO2019143943A2 (en) 2018-01-19 2019-07-25 Yin To Chiu Composition and method for concentration and enrichment of nucleic acids
BR112022025736A2 (en) * 2020-06-15 2023-03-07 Neuome Peptides Pte Ltd SIDE FLOW TEST DEVICE FOR ANALYTES DETECTION AND METHOD OF DETECTION THEREOF

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304310A (en) * 1990-01-18 1994-04-19 Basf Aktiengesellschaft Method for concentrating and purifying hirudin from leeches
US5772888A (en) * 1995-07-27 1998-06-30 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
US5798273A (en) * 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
US6699722B2 (en) * 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304310A (en) * 1990-01-18 1994-04-19 Basf Aktiengesellschaft Method for concentrating and purifying hirudin from leeches
US5772888A (en) * 1995-07-27 1998-06-30 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
US5798273A (en) * 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
US6699722B2 (en) * 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MASHAYEKHI, F. ET AL.: "Enhancing the Lateral-flow Immunoassay for Viral Detection Using an Aqueous Two-phase Micellar System", ANAL. BIOANAL. CHEM., vol. 398, no. 7-8, September 2010 (2010-09-01), pages 2955 - 2961 *

Also Published As

Publication number Publication date
WO2011159537A2 (en) 2011-12-22

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