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WO2010062996A3 - Ribavirin composition - Google Patents

Ribavirin composition Download PDF

Info

Publication number
WO2010062996A3
WO2010062996A3 PCT/US2009/065992 US2009065992W WO2010062996A3 WO 2010062996 A3 WO2010062996 A3 WO 2010062996A3 US 2009065992 W US2009065992 W US 2009065992W WO 2010062996 A3 WO2010062996 A3 WO 2010062996A3
Authority
WO
WIPO (PCT)
Prior art keywords
ribavirin composition
ribavirin
composition
excipients
pharmaceutically
Prior art date
Application number
PCT/US2009/065992
Other languages
French (fr)
Other versions
WO2010062996A2 (en
Inventor
Ashok Katdare
Kavita Vermani
Original Assignee
Adamas Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adamas Pharmaceuticals, Inc. filed Critical Adamas Pharmaceuticals, Inc.
Publication of WO2010062996A2 publication Critical patent/WO2010062996A2/en
Publication of WO2010062996A3 publication Critical patent/WO2010062996A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A pharmaceutically-acceptable ribavirin composition is provided that requires few processing steps and excipients and provides high drug loading in oral dosage forms.
PCT/US2009/065992 2008-11-28 2009-11-25 Ribavirin composition WO2010062996A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11858308P 2008-11-28 2008-11-28
US61/118,583 2008-11-28

Publications (2)

Publication Number Publication Date
WO2010062996A2 WO2010062996A2 (en) 2010-06-03
WO2010062996A3 true WO2010062996A3 (en) 2010-09-10

Family

ID=42226382

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/065992 WO2010062996A2 (en) 2008-11-28 2009-11-25 Ribavirin composition

Country Status (1)

Country Link
WO (1) WO2010062996A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106806345B (en) * 2015-11-27 2020-10-13 北京科信必成医药科技发展有限公司 Ribavirin taste masking granules and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030104050A1 (en) * 2001-11-02 2003-06-05 Matharu Amol Singh Process for preparing quick dissolving, high loading ribavirin compositions
US20050019406A1 (en) * 2002-09-19 2005-01-27 Three Rivers Pharmaceuticals, Llc Composition containing ribavirin and use thereof
US20050075297A1 (en) * 2001-03-19 2005-04-07 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
US20070166378A1 (en) * 2005-06-09 2007-07-19 Flamel Technologies, Inc. Oral ribavirin pharmaceutical compositions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050075297A1 (en) * 2001-03-19 2005-04-07 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
US20030104050A1 (en) * 2001-11-02 2003-06-05 Matharu Amol Singh Process for preparing quick dissolving, high loading ribavirin compositions
US20050019406A1 (en) * 2002-09-19 2005-01-27 Three Rivers Pharmaceuticals, Llc Composition containing ribavirin and use thereof
US20070166378A1 (en) * 2005-06-09 2007-07-19 Flamel Technologies, Inc. Oral ribavirin pharmaceutical compositions

Also Published As

Publication number Publication date
WO2010062996A2 (en) 2010-06-03

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