WO2010058796A1

WO2010058796A1 - Leak detection system

Info

Publication number: WO2010058796A1
Application number: PCT/JP2009/069564
Authority: WO
Inventors: 茂根本; 正博榊原
Original assignee: 株式会社根本杏林堂
Priority date: 2008-11-19
Filing date: 2009-11-18
Publication date: 2010-05-27
Also published as: JP2016093530A; JP5897798B2; JPWO2010058796A1

Abstract

Provided is a leak detection system which can effectively detect a leak even when a patient has moved during administration of a chemical liquid and the movement has caused a leak of the chemical liquid out of a blood vessel. The leak detection system (1) includes: a leak detection device (20) which detects a leak out of a blood vessel during administration of a chemical liquid to a patient; and a transmission means which radio-transmits to a monitor terminal, the information relating to the leak out of the blood vessel detected by the leak detection device (20).

Description

Leak detection system

The present invention relates to a leakage detection system for detecting extravasation during the administration of a drug solution to a patient, and in particular, the patient moves during administration of a drug solution, and the blood vessel is moved at the destination. An object of the present invention is to provide a leak detection system that can detect a leak even if an external leak occurs.

Conventionally, when a medicinal solution such as a nutrient is administered to a patient by infusion, it needs to be administered for a relatively long time, for example, 1 hour to several hours. In addition, in such drug solution administration, the tip of the injection needle may be detached from the blood vessel during administration, and the drug solution may be administered subcutaneously (this is referred to as “extravascular leakage”).

On the other hand, in such long-term drug administration, the patient may go to a toilet or the like while instilling. Therefore, there is a possibility that the tip of the injection needle is detached from the blood vessel at a place other than the hospital room and extravasation occurs.
If the drug solution is a nutrient, etc., extravasation may occur, and even if the drug solution is injected subcutaneously, the effect on the human body is relatively small. There is a risk that the tissue becomes hard or in some cases necrotic. Therefore, it is desirable to detect such extravasation as soon as possible.

By the way, as means for detecting extravasation as described above, for example, Patent Document 1 includes a light emitting element that emits light toward the vicinity of a blood vessel, and a light receiving element that receives the reflected light. A device used by being attached to an arm (one example) is disclosed.

WO2006-030764

In the conventional leak detection means described in Patent Document 1, it is possible to detect the extravasation of the drug solution (for example, contrast medium) well, but the patient moves out of the room while the drug solution is being injected. Is not assumed.
Accordingly, an object of the present invention is to provide a leak detection system that can detect a leak well even when a patient moves during administration of a drug solution and an extravasation occurs at the destination.

In order to achieve the above object, the leak detection system of the present invention includes:
A leak detection device for detecting extravasation when administering a liquid medicine to a patient;
A monitoring terminal located in the hospital facility;
Transmitting means for wirelessly transmitting extravasation information detected by the leak detection device to the monitoring terminal.

According to the leak detection system of the present invention, since the transmission means for wirelessly transmitting extravasation information is provided, the patient moves out of the hospital room while the drug solution is being administered. Even when extravasation occurs, the leak can be detected well.

As used herein, “administering a drug solution” is intended to have a relatively slow infusion rate such as administration by infusion or administration using a drug solution pump (detailed later). It is intended that the patient moves out of the room during administration and extravasation may occur at the destination (outside the room, etc.).

In addition, the system of the present invention may further have a function of storing a time from the start of the drug solution administration to the occurrence of the extravasation.
In this case, since the amount of the chemical solution that has already been introduced can be estimated, it is possible to satisfactorily determine the remaining amount to be administered when the administration of the chemical solution is resumed.

Further, in another system of the present invention, a plurality of relays that receive information transmitted from the transmitting means and send the information to the monitoring terminal are arranged in a hospital facility, and as the patient position information, Position information of the repeater is sent to the monitoring terminal.
Moreover, when the said repeater is arrange | positioned in the several floor in a hospital facility, even if a patient moves to another floor, there exists an advantage that a patient's position can be detected.

The infusion pump of the present invention is an infusion pump for administering a drug solution to a patient,
A receiving unit for receiving information on the extravasation transmitted from the leak detection device for detecting extravasation when administering a drug solution to a patient;
A transmission unit that wirelessly transmits the extravasation information to a monitoring terminal disposed in the hospital facility.
Here, the system of the “infusion pump” is not particularly limited, and may be a finger pump, a roller pump, a syringe pump, or the like.

The various means referred to in the present invention need only be formed so as to realize the function. For example, dedicated hardware that exhibits a predetermined function, a data processing apparatus provided with a predetermined function by a computer program It can be realized as a predetermined function implemented in the data processing apparatus by a computer program, a combination thereof, or the like.

In addition, the various constituent elements referred to in the present invention do not necessarily have to be individually independent, and a plurality of constituent elements are formed as one member, and one constituent element is formed from a plurality of members. It is possible that a certain component is a part of another component, a part of a certain component overlaps a part of another component, and the like.

As described above, according to the present invention, even when a patient moves during administration of a medical solution and an extravasation occurs at the movement destination, the leak detection system can detect the leak well. Can be provided.

It is a figure which shows the leak detection system of one Embodiment of this invention. It is a figure which shows a chemical | medical solution bag and a leak detection unit. It is an exploded view which shows the structure of a leak detection unit. It is a graph which shows the change of the intensity | strength of reflected light when extravascular leakage has occurred. It is a figure which shows the structure of 2nd Embodiment. It is a schematic block diagram of an infusion pump. It is a figure which shows an example of an electromagnetic induction type charging device. It is a typical block diagram of the leak detection unit of other forms.

Hereinafter, an embodiment of the present invention will be described with reference to the drawings.
(First embodiment)
FIG. 1 is a diagram showing a leakage detection system according to an embodiment of the present invention, and shows an example in which a system is constructed in a hospital facility. FIG. 2 is a diagram illustrating a chemical solution bag and a leakage detection unit.

In the following description, words indicating directions such as “up and down” and “left and right” may be used in accordance with the description of the drawings, but these do not limit the present invention. Also, the position where the injection needle is inserted is not limited to that shown in FIG.

As shown in FIG. 1, this leak detection system 1 is used in a hospital facility as an example, and a leak detection unit 20 (for detecting extravasation when a drug solution is administered to a patient) 2), a plurality of repeaters 30 that are arranged in several places in the hospital facility and receive radio signals, a center console 40 that is arranged in the nurse station and is connected to the repeater 30 by wire or wirelessly, It has.
In the system of the present invention, the repeater 30 may be omitted. This will be described later.

In this embodiment, as an example, a drug solution (for example, an anticancer drug) is administered to a patient in a hospital room 201. As shown in FIG. 2, the drug solution is accommodated in a drug solution bag 83 suspended from the upper part of the movable stand 81, and is administered to the blood vessel of the patient's arm via the tube 85. Since the stand 81 is movable, the patient can leave the hospital room 201 (see FIG. 1) and go to the toilet 204, for example, even during the administration of the drug solution.

As shown in FIGS. 2 and 3, the leakage detection unit 20 includes a flat circular housing 21, a substrate 22 and a coin-type battery 23 (for example, a lithium secondary battery) disposed therein. On the lower surface of the substrate 22, a light emitting diode that irradiates light around the blood vessel of the patient and a phototransistor that detects the reflected light are disposed downward. In addition, a conventionally well-known thing can be utilized for these leak detection devices. Light rays from the light emitting diodes are applied to the patient's skin through an opening in the bottom surface of the housing 21.

The light emitting diode may emit infrared rays. The principle of detecting extravasation using infrared light is the same as that described in Patent Document 1 (WO 2006-030764) and the like, and will be briefly described below. In the state where no chemical liquid leaks under the arm of the patient, as shown in FIG. 4A, the intensity of the wavelength band of the reflected light to be detected is equal, but when the chemical liquid leaks, FIG. As shown in FIG. 4, the detected reflected light is extremely lowered only at a specific wavelength. The detection unit 20 determines whether extravasation has occurred based on this difference.

The substrate 22 is also mounted with a control circuit that performs predetermined arithmetic processing and a wireless antenna 22a that transmits to the outside that an extravasation has occurred. As a wireless system, for example, the Zigbee (registered trademark) standard using a frequency band of 2.45 GHz can be used from the viewpoint of power consumption and the like.

The center console 40 is a monitoring terminal and is arranged in each of the

nurse stations

108 and 208 as shown in FIG. Although illustration is omitted, the center console 40 includes a display (display means) for displaying a warning message when information on extravasation is received. Each center console 40 may be mutually connected by LAN, for example.

As shown in FIG. 1, the repeater 30 is arranged on a plurality of floors of a hospital facility. In this example, they are arranged in a hospital room 201 and a toilet 204 where a medical solution is administered to a patient, and a patient room 101 and a toilet 104 on the floor below. The repeater 30 may be attached near the ceiling, for example.
The repeater 30 has a function of receiving a radio signal from the detection unit 20 when extravasation occurs and a function of sending the information to the center console 40. Communication between the repeater 30 and the center console 40 may be wired communication or wireless communication.

In order to recognize the position of the patient in the hospital facility at the time when extravasation has occurred, the position information of the repeaters is stored in advance in each repeater 30. When extravasation occurs, the position information is also sent to the console 40. The positional information is displayed on the display of the console 40 together with the fact that extravasation has occurred.

With such a configuration, it is possible to inform the nurse in the nurse station 208 of the positional information of the patient in the hospital facility at the time when extravasation occurs. The information (extravasation information and patient position information) may be sent directly from the detection unit 20 to the center console 40 without the relay 30 being interposed.

The operation of the leak detection system 1 of the present embodiment configured as described above will be described below.

First, the patient enters the hospital room 201, and the injection needle at the tip of the tube 85 is inserted into the blood vessel (an example) of the arm. Then, the detection unit 20 is arranged from above so that extravasation can be detected (see FIG. 2), and then administration of the drug solution is started.
The method for fixing the detection unit 20 to the patient's arm is not particularly limited, and the unit 20 may be fixed by a transparent double-sided sheet 29 as shown in FIG. The unit 20 may be fixed by using (shown).

As shown in FIG. 1, if the patient moves toward the toilet 204 while the drug solution is being administered and the injection needle is removed from the blood vessel outside the hospital room, the drug solution is administered subcutaneously.

The leak detection unit 20 emits infrared light of a predetermined wavelength band with a light emitting diode near the position where the injection needle is inserted into the blood vessel, and detects the reflected light with a phototransistor. Specifically, as in the conventional configuration, the intensity of a specific wavelength is measured among infrared rays in a predetermined wavelength band to be detected, and the average intensity of the wavelength band is also measured. The ratio of the intensity of the specific wavelength to the average intensity of the light beam in the wavelength band thus measured is calculated, and the calculated ratio is compared with a predetermined reference value. If the ratio is not lower than the reference value, the occurrence of leakage of the chemical liquid is not determined, and the leakage detection unit transmits, as an example, a standby signal (wireless signal) indicating “no leakage”.
On the other hand, if the ratio is lower than the reference value, the occurrence of leakage of the chemical solution is determined, and the leakage detection unit 20 transmits a warning signal (radio signal) indicating “leak occurrence” to the outside via the antenna 22a. To do.

In this example, the extravasation information transmitted from the detection unit 20 is received by the toilet relay 30 and sent to the console 40 in the nurse station 201 via the relay 30. At this time, the position information stored in advance in the repeater 30 is also sent to the console 40.

Upon receiving the above information, the console 40 displays on the display that extravasation has occurred and the position information of the patient at the time of occurrence (position of the relay 30).

Even when the patient moves to the lower floor (the first floor) and an extravasation occurs there, the signal from the detection unit 20 is received by the predetermined repeater 30 on the first floor as described above. Information is sent to the console 40 in the nurse station 108 via the repeater 30.

According to the above configuration, even if extravasation occurs outside the hospital room 201, it is well detected that the leak has occurred by wireless communication. It is also possible to know information on the position where the leak has occurred. Therefore, the nurse in the nurse station can quickly go to the patient and deal with extravasation.

In the present embodiment, only the fact that extravasation has occurred may be sent to the console 40 without transmitting the position information.

According to the system 1 of the present embodiment, particularly when an extravasation occurs in the administration of an anticancer agent or the like, the leakage of the drug solution to the outside of the blood vessel is minimized, and damages such as tissue hardening and necrosis are prevented. This is advantageous in that it can be prevented.

As shown in FIG. 1, since the repeater 30 is also arranged in the hospital room 201, it is natural that the extravasation in the hospital room 201 can be notified to the nurse in the nurse station 208. For example, when an infusion is performed during sleep, extravasation caused by the injection needle coming off the blood vessel while sleeping can also be detected.

In the present embodiment, the position information at the time when extravasation occurs may be recognized by the detection unit 20 itself, and the information may be transmitted to the console 40.
When administration of a chemical solution is performed on a plurality of patients simultaneously, it is preferable that ID data for each patient is also transmitted from the detection unit 20 in order to identify the patient.

Even if the repeater 30 is not used, the console 40 is provided on each floor, and information from the detection unit 20 is received by the console 40 on the floor where the unit 20 exists (the floor where the patient is present). Even if it is not possible to specify the detailed position of the patient, it is possible to specify at least what floor the patient is on.

Further, the detection unit 20 may be provided with alarm means such as an LED or a speaker, and the alarm means may be driven when the unit 20 detects extravasation.

Further, the present system 1 may further have a function of storing the time from the start of drug administration to the occurrence of extravasation. According to such a configuration, when the administration of the drug solution is resumed, it is possible to satisfactorily determine how much of the remaining amount should be administered.
As an example of a method for measuring the time from the start of drug administration to the occurrence of extravasation, as an example, the detection unit 20 itself has a function of measuring the time, and the occurrence of extravasation from the start of drug administration The time until the time is measured and the information may be transmitted to the console 40. Alternatively, the console 40 may be able to measure the time from the start of drug solution administration to the occurrence of extravasation. This time information may be stored in the unit 20 or the console 40 as required.

(Second Embodiment)
FIG. 5 is a diagram illustrating a part of the leakage detection system according to the second embodiment.
As shown in FIG. 5, this invention is applicable also when administering a chemical | medical solution using an infusion pump.

This chemical pump 90 is a finger pump (one example) that is used by being attached to a stand 81, and includes a display 93 that displays predetermined information such as a flow rate, a finger portion that pressurizes a tube, a built-in battery, etc., not shown. Have. Moreover, a bubble sensor, a pressure sensor, a drop sensor, etc. may be incorporated.

As shown in FIG. 6, the chemical pump 90 includes a calculation unit 91 that performs various calculations, a reception unit 95 that is connected to the leak detection unit 20 by wire or wirelessly and receives information on extravasation from the unit 20, It has the transmission part 93 which transmits the information of extravascular leakage to the exterior by radio | wireless, and the drive part 97 corresponded to a finger part.

In the chemical pump 90 configured as described above, the information on extravasation from the detection unit 20 is received by the receiving unit 95, and the information is transmitted to the console 40 (see FIG. 1) via the transmitting unit 93. . When the information on extravasation is received, the calculation unit 91 may be configured to send a drive stop signal to the drive unit 97.

In addition, the infusion pump 90 may have a function of transmitting the position information of the patient in the hospital facility at the time when the extravasation occurs together with the extravasation information as in the first embodiment. .

Note that the example of FIG. 5 shows a configuration in which the infusion pump 90 and the leak detection unit 20 are connected to each other by a cord 28. In this case, the built-in battery of the infusion pump 90 can also be used as a power source for the detection unit 20. Further, when extravasation occurs, that fact may be displayed on the display 93 of the infusion pump 90.

FIG. 7 is a diagram showing a charging device 120 for the built-in battery 23 of the leakage detection unit 20 shown in FIG.
The charging device 120 is a non-contact type charger that charges a battery in the detection unit 20 using electromagnetic induction. In this example, the charging device 120 includes a substantially plate-shaped holding unit 122 in which a plurality of detection units 20 can be arranged. A power transmission coil (not shown) is built in the holding unit 122, and a power reception coil 27 (see FIG. 3) is built in one detection unit 20.

According to such a non-contact type charging device, it is not necessary to provide a metal contact for charging in the leakage detection unit 20, and therefore, it is particularly suitable for the unit 20 of the present embodiment that detects leakage of a chemical solution.

In addition, the plate-shaped holding part 122 of the charging device 120 may be provided with a recess into which each unit 20 is fitted, or may be provided with an indicator such as an LED that indicates completion of charging.

As mentioned above, although one form of this invention was demonstrated, as a "chemical | medical solution", it is not limited to an anticancer agent, For example, a common nutrient drop may be sufficient.
As a principle for detecting extravasation, other than using infrared rays, it may be possible to detect the occurrence of extravasation by detecting swelling of the skin due to the leakage of the chemical solution.

The leak detection unit 20 may transmit a warning signal only when extravasation occurs, or indicates “no leak” even if no extravasation occurs as in the above embodiment. It may be configured to transmit a standby signal.

As a method for detecting patient position information, for example, in a configuration in which a plurality of repeaters 30 are arranged in a hospital facility, the leakage detection unit 20 and the plurality of repeaters 30 can be connected using wireless communication. The positional relationship with several units (for example, three units or four units) may be calculated, and the patient position information may be acquired by performing surveying based on the calculated positional relationship.

FIG. 8 is a diagram schematically showing a circuit configuration of a leakage detection unit according to still another embodiment of the present invention.
As shown in FIG. 8, the leak detection unit 20 ′ includes a control unit 26 that performs various calculations, and a leak detection device 26a connected thereto (similar to the first embodiment, a light emitting diode or the like). And a temperature sensor 26b connected to the control unit 26. An optical sensor may be used instead of this temperature sensor.

The temperature sensor 26b is disposed on the lower surface side of the unit 20 ′ (see FIG. 3), and measures the temperature of the patient's body surface when the unit 20 ′ is normally attached to the patient's body. When the unit 20 'is removed from the patient's body for some reason (separated), the temperature sensor 26b measures the temperature of the outside air (one example) instead of the body surface.
By using this detection result by the temperature sensor 26b, it is possible to detect whether or not the unit 20 'is normally attached to the patient's body.

The following determination can be performed by using the leakage detection unit 20 ′ having the above configuration.
First, when the detection results of the leakage detection device 26a and the temperature sensor 26b are both normal (no leakage / human body temperature), it is determined that the unit 20 'is normally attached and operating normally. If the detection result of the device 26a is abnormal (leakage is present) and the detection result of the sensor 26b is normal (human body temperature), it is determined that the unit 20 'is normally attached but leakage has occurred. Further, when both the detection results of the device 26a and the sensor 26b are abnormal (leakage / outside air temperature), it is determined that the unit 20 ′ is detached from the patient's body.

According to the above configuration, not only extravasation but also whether or not the leak detection unit 20 ′ is normally attached to the patient's body can be determined, so that safer drug administration can be performed. it can.

DESCRIPTION OF SYMBOLS 1 Leak detection system 20, 20 'Leak detection unit 22a Antenna 23 Battery 26 Control part 26a Leak detection device 26b Temperature sensor 29 Double-sided sheet 30 Repeater 40 Center console 81 Stand 83 Chemical solution bag 85 Tube 90

Infusion pump

101, 201 Hospital room 104 204

Toilet

108, 208 Nurse station 120 Charging device

Claims

A leak detection device for detecting extravasation when administering a liquid medicine to a patient;
A monitoring terminal located in the hospital facility;
Transmitting means for wirelessly transmitting information on extravasation detected by the leak detection device to the monitoring terminal;
A leakage detection system comprising:
The leak detection system according to claim 1, wherein the information on the position of the patient in the hospital facility at the time when the extravasation occurs is transmitted to the monitoring terminal together with the extravasation information.
further,
The leak detection system according to claim 1, wherein the leak detection system has a function of storing a time from the start of the administration of the drug solution to the occurrence of the extravasation.
The leak detection device is
It is a unit attached to the patient's body surface that contains a light emitting element that irradiates light toward the patient's blood vessel and a light receiving element that receives the reflected light.
The leakage detection system according to any one of claims 1 to 3, further comprising the transmission means.
The leakage detection system according to any one of claims 1 to 4, wherein the transmission means is provided in an infusion pump for administering a drug solution to a patient.
A plurality of relays that receive the information transmitted from the transmitting means and send the information to the monitoring terminal are arranged in a hospital facility,
The leakage detection system according to any one of claims 1 to 5, wherein the position information of the repeater is sent to the monitoring terminal as the position information of the patient.
The leak detection system according to claim 6, wherein the repeater is arranged on a plurality of floors in a hospital facility.
The leak detection system according to any one of claims 1 to 7, wherein the monitoring terminal includes a display unit, and a warning message is displayed on the display unit when the extravasation information is received.
The chemical solution leakage system according to any one of claims 1 to 8, wherein the chemical solution is an anticancer agent.
The leak detection device is
It is a unit attached to the patient's body surface that contains a light emitting element that irradiates light toward the patient's blood vessel and a light receiving element that receives the reflected light.
further,
The leak detection system according to claim 1, comprising a temperature sensor or a light sensor for detecting whether the unit is normally attached to the patient's body surface.
An infusion pump for administering a drug solution to a patient,
A receiving unit for receiving information on the extravasation transmitted from the leak detection device for detecting extravasation when administering a drug solution to a patient;
An infusion pump comprising: a transmitter that wirelessly transmits the extravasation information to a monitoring terminal arranged in a hospital facility.
The transmitter is
The infusion pump according to claim 11, wherein information on the position of a patient in a hospital facility at the time when the extravasation occurs is transmitted to the monitoring terminal together with the extravasation information.
The infusion pump according to claim 11 or 12, wherein the infusion operation is automatically stopped when the extravasation is detected.