WO2009013545A3 - Composés chimiques - Google Patents
Composés chimiques Download PDFInfo
- Publication number
- WO2009013545A3 WO2009013545A3 PCT/GB2008/050617 GB2008050617W WO2009013545A3 WO 2009013545 A3 WO2009013545 A3 WO 2009013545A3 GB 2008050617 W GB2008050617 W GB 2008050617W WO 2009013545 A3 WO2009013545 A3 WO 2009013545A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- chemical compounds
- methods
- compounds
- treatmentfor
- cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cette invention se rapporte à des composés de formule (I) et à leurs sels, à des compositions pharmaceutiques, à leurs procédés d'utilisation et à leurs procédés de préparation. Ces composés sont utilisés dans le traitement du syndrome myéloprolifératif et du cancer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95222207P | 2007-07-26 | 2007-07-26 | |
US60/952,222 | 2007-07-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009013545A2 WO2009013545A2 (fr) | 2009-01-29 |
WO2009013545A3 true WO2009013545A3 (fr) | 2009-07-02 |
Family
ID=40281894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2008/050617 WO2009013545A2 (fr) | 2007-07-26 | 2008-07-23 | Composés chimiques |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009013545A2 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2754890C (fr) | 2009-03-13 | 2018-01-16 | Piet Herdewijn | Heterocycles bicycliques |
AU2011206617B2 (en) | 2010-01-14 | 2015-07-16 | Sanofi | 2,5-substituted oxazolopyrimidine derivatives |
KR101483215B1 (ko) * | 2010-01-29 | 2015-01-16 | 한미약품 주식회사 | 단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체 |
US20130317045A1 (en) * | 2010-09-01 | 2013-11-28 | Ambit Biosciences Corporation | Thienopyridine and thienopyrimidine compounds and methods of use thereof |
WO2013113715A1 (fr) | 2012-02-03 | 2013-08-08 | Basf Se | Composés de pyrimidine fongicides |
CA2865043A1 (fr) | 2012-03-13 | 2013-09-19 | Basf Se | Composes de pyrimidine fongicides |
CN103242341B (zh) * | 2013-04-19 | 2015-12-09 | 中国科学院广州生物医药与健康研究院 | 噻吩并2,4取代嘧啶类化合物及其药物组合物与应用 |
EP3046915A1 (fr) | 2013-09-16 | 2016-07-27 | Basf Se | Composés pyrimidines fongicides |
WO2015036059A1 (fr) | 2013-09-16 | 2015-03-19 | Basf Se | Composés fongicides de pyrimidine |
WO2016030534A1 (fr) | 2014-08-29 | 2016-03-03 | Tes Pharma S.R.L. | Inhibiteurs de la semialdéhyde décarboxylase de l'acide alpha-amino-bêta-carboxymuconique |
JP7078960B2 (ja) | 2017-01-26 | 2022-06-01 | エス. トサントリゾス,ヨウラ | 置換二環式ピリミジン系化合物および組成物ならびにその使用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002050065A2 (fr) * | 2000-12-21 | 2002-06-27 | Vertex Pharmaceuticals Incorporated | Composes de pyrazole presentant une grande utilite comme inhibiteurs de proteine kinase |
WO2005049033A1 (fr) * | 2003-11-17 | 2005-06-02 | Astrazeneca Ab | Derives de pyrazole en tant qu'inhibiteurs de recepteur tyrosine kinases |
WO2006123113A2 (fr) * | 2005-05-16 | 2006-11-23 | Astrazeneca Ab | Composes chimiques |
WO2007049041A1 (fr) * | 2005-10-28 | 2007-05-03 | Astrazeneca Ab | Derives 4-(3-aminopyrazole)pyrimidine et leur utilisation en tant qu’inhibiteurs de tyrosine kinases dans le cadre d’un traitement anticancereux |
-
2008
- 2008-07-23 WO PCT/GB2008/050617 patent/WO2009013545A2/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002050065A2 (fr) * | 2000-12-21 | 2002-06-27 | Vertex Pharmaceuticals Incorporated | Composes de pyrazole presentant une grande utilite comme inhibiteurs de proteine kinase |
WO2005049033A1 (fr) * | 2003-11-17 | 2005-06-02 | Astrazeneca Ab | Derives de pyrazole en tant qu'inhibiteurs de recepteur tyrosine kinases |
WO2006123113A2 (fr) * | 2005-05-16 | 2006-11-23 | Astrazeneca Ab | Composes chimiques |
WO2007049041A1 (fr) * | 2005-10-28 | 2007-05-03 | Astrazeneca Ab | Derives 4-(3-aminopyrazole)pyrimidine et leur utilisation en tant qu’inhibiteurs de tyrosine kinases dans le cadre d’un traitement anticancereux |
Also Published As
Publication number | Publication date |
---|---|
WO2009013545A2 (fr) | 2009-01-29 |
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