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WO2009087578A3 - Sensation modifying topical composition foam - Google Patents

Sensation modifying topical composition foam Download PDF

Info

Publication number
WO2009087578A3
WO2009087578A3 PCT/IB2009/005005 IB2009005005W WO2009087578A3 WO 2009087578 A3 WO2009087578 A3 WO 2009087578A3 IB 2009005005 W IB2009005005 W IB 2009005005W WO 2009087578 A3 WO2009087578 A3 WO 2009087578A3
Authority
WO
WIPO (PCT)
Prior art keywords
sensation
agent
composition
topical composition
sensation modifying
Prior art date
Application number
PCT/IB2009/005005
Other languages
French (fr)
Other versions
WO2009087578A2 (en
Inventor
Dov Tamarkin
Meir Eini
Doron Friedman
Ella Zlatkis
David Schuz
Tal Berman
Original Assignee
Foamix Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/971,197 external-priority patent/US20080253973A1/en
Application filed by Foamix Ltd. filed Critical Foamix Ltd.
Priority to CA2711703A priority Critical patent/CA2711703A1/en
Publication of WO2009087578A2 publication Critical patent/WO2009087578A2/en
Publication of WO2009087578A3 publication Critical patent/WO2009087578A3/en
Priority to ZA2010/05630A priority patent/ZA201005630B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/16—Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/242—Exothermic; Self-heating; Heating sensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/244—Endothermic; Cooling; Cooling sensation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

This invention relates to foamable compositions that are capable of producing a sensation or sensation modifying effect upon application on a body surface. More particularly the invention relates to a composition that provides to a subject at least one sensation for a sustained period of time following application to the skin. The composition includes (a) at least one sensation or sensation modifying agent, comprising one or more of a cooling agent, a warming agent, a relaxing or soothing agent, and a stimulating or refreshing agent; (b) a foamable carrier; and (c) a propellant having a concentration about 3% to about 45% by weight of the total composition. The composition is stored in an aerosol container and upon release expands to form a non-crackling short term stable foam.
PCT/IB2009/005005 2008-01-08 2009-01-08 Sensation modifying topical composition foam WO2009087578A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2711703A CA2711703A1 (en) 2008-01-08 2009-01-08 Sensation modifying topical composition foam
ZA2010/05630A ZA201005630B (en) 2008-01-08 2010-08-04 Sensation modifying topical composition foam

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/971,197 2008-01-08
US11/971,197 US20080253973A1 (en) 2002-10-25 2008-01-08 Sensation modifying topical composition foam

Publications (2)

Publication Number Publication Date
WO2009087578A2 WO2009087578A2 (en) 2009-07-16
WO2009087578A3 true WO2009087578A3 (en) 2010-06-10

Family

ID=40853523

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/005005 WO2009087578A2 (en) 2008-01-08 2009-01-08 Sensation modifying topical composition foam

Country Status (3)

Country Link
CA (1) CA2711703A1 (en)
WO (1) WO2009087578A2 (en)
ZA (1) ZA201005630B (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8518378B2 (en) 2003-08-04 2013-08-27 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8865139B1 (en) 2009-10-02 2014-10-21 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US9072667B2 (en) 2009-07-29 2015-07-07 Foamix Pharmaceuticals Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9101662B2 (en) 2003-08-04 2015-08-11 Foamix Pharmaceuticals Ltd. Compositions with modulating agents
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
WO2019175290A1 (en) 2018-03-13 2019-09-19 Beckley Canopy Therapeutics Limited Cannabis or cannabis derived compositions for promoting cessation of chemical dependence
CN109715251B (en) * 2016-09-19 2024-06-21 宝洁公司 Foam composition, aerosol product and method of use thereof for improving sensory benefits to skin

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
WO2004037225A2 (en) 2002-10-25 2004-05-06 Foamix Ltd. Cosmetic and pharmaceutical foam
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
ATE429255T1 (en) 2005-03-24 2009-05-15 Nolabs Ab COSMETIC TREATMENT WITH NITROGEN OXIDE, DEVICE FOR PERFORMING SUCH TREATMENT AND PRODUCTION METHOD THEREOF
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2009090558A2 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US9919072B2 (en) 2009-08-21 2018-03-20 Novan, Inc. Wound dressings, methods of using the same and methods of forming the same
EP2467127B1 (en) 2009-08-21 2023-08-02 Novan, Inc. Topical gels
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
ES2529506T3 (en) * 2010-06-11 2015-02-20 Leo Pharma A/S A pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid
WO2013006608A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Topical compositions
WO2013006613A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Methods of manufacturing topical compositions and apparatus for same
WO2013138075A1 (en) 2012-03-14 2013-09-19 Novan, Inc. Nitric oxide releasing pharmaceutical compositions
EP2950823B1 (en) 2013-02-01 2020-07-01 Ddrops Company Liquid menthol compositions
ES2701758T3 (en) 2013-02-27 2019-02-25 Symrise Ag Ginger extract for the protection of stem cells
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
JP6513667B2 (en) 2013-08-08 2019-05-15 ノヴァン，インコーポレイテッド Topical composition and method of using the same
ES2807200T3 (en) 2014-07-11 2021-02-22 Novan Inc Topical antiviral compositions and procedures for their use
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
US10925689B2 (en) 2014-07-14 2021-02-23 Novan, Inc. Nitric oxide releasing nail coating compositions, nitric oxide releasing nail coatings, and methods of using the same
CN105813617B (en) 2014-08-08 2021-05-28 诺万公司 Topical compositions and methods of using the same
EP3097905B1 (en) 2015-05-28 2020-11-04 Symrise AG Cosmetic compositions
WO2017019614A1 (en) 2015-07-28 2017-02-02 Novan, Inc. Combinations and methods for the treatment and/or prevention of fungal infections
ITUB20160058A1 (en) * 2016-01-19 2017-07-19 Farm S R L C U S Composition of a preparation for the treatment of insect bites with vasoconstrictive, soothing, anti-inflammatory and anti-reddening activity
EP3423100A4 (en) 2016-03-02 2019-10-16 Novan, Inc. Compositions for treating inflammation and methods of treating the same
WO2017180822A1 (en) 2016-04-13 2017-10-19 Novan, Inc. Compositions, systems, kits, and methods for treating an infection
EP3463588A1 (en) 2016-05-30 2019-04-10 Symrise AG Medicament comprising ginger root co2 extract
BR112018074709B1 (en) 2016-05-30 2022-01-18 Symrise Ag DRUG INCLUDING SCLAREOLIDE, NON-THERAPEUTIC METHOD FOR THE TREATMENT OF VISIBLE LIGHT-INDUCED HYPERPIGMENTATION IN THE RANGE OF 400 NM TO 700 NM, AND NON-THERAPEUTIC COSMETIC USE OF SCLAREOLIDE
BR112018076198A2 (en) 2016-06-30 2019-03-26 Symrise Ag medicament and cosmetic composition comprising resorcinol derivatives
MX2020012139A (en) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Compositions and methods for treating rosacea and acne.
BR112019010812A2 (en) * 2016-12-02 2019-10-01 Symrise Ag cosmetic blends
EP3758679A4 (en) 2018-03-01 2021-12-15 Novan, Inc. Nitric oxide releasing suppositories and methods of use thereof
EP4031099B1 (en) * 2019-09-20 2023-03-01 Unilever IP Holdings B.V. Antiperspirant compositions
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Citations (5)

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EP0414920A1 (en) * 1989-03-17 1991-03-06 Taisho Pharmaceutical Co. Ltd Aerosol preparation for external use
EP0484530A1 (en) * 1989-07-28 1992-05-13 Hisamitsu Pharmaceutical Co., Inc. Foamed aerosol preparation
WO1992011839A1 (en) * 1991-01-08 1992-07-23 Leonard Mackles Anhydrous aerosol
EP0993827A1 (en) * 1997-06-13 2000-04-19 Taisho Pharmaceutical Co., Ltd Aerosols
JP2001072963A (en) * 1999-09-03 2001-03-21 Daizo:Kk Water-in-oil type bubblelike aerosol composition and preparation thereof

Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
EP0414920A1 (en) * 1989-03-17 1991-03-06 Taisho Pharmaceutical Co. Ltd Aerosol preparation for external use
EP0484530A1 (en) * 1989-07-28 1992-05-13 Hisamitsu Pharmaceutical Co., Inc. Foamed aerosol preparation
WO1992011839A1 (en) * 1991-01-08 1992-07-23 Leonard Mackles Anhydrous aerosol
EP0993827A1 (en) * 1997-06-13 2000-04-19 Taisho Pharmaceutical Co., Ltd Aerosols
JP2001072963A (en) * 1999-09-03 2001-03-21 Daizo:Kk Water-in-oil type bubblelike aerosol composition and preparation thereof

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8518378B2 (en) 2003-08-04 2013-08-27 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9101662B2 (en) 2003-08-04 2015-08-11 Foamix Pharmaceuticals Ltd. Compositions with modulating agents
US9072667B2 (en) 2009-07-29 2015-07-07 Foamix Pharmaceuticals Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US8865139B1 (en) 2009-10-02 2014-10-21 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
US8992896B2 (en) 2009-10-02 2015-03-31 Foamix Pharmaceuticals Ltd. Topical tetracycline compositions
CN109715251B (en) * 2016-09-19 2024-06-21 宝洁公司 Foam composition, aerosol product and method of use thereof for improving sensory benefits to skin
WO2019175290A1 (en) 2018-03-13 2019-09-19 Beckley Canopy Therapeutics Limited Cannabis or cannabis derived compositions for promoting cessation of chemical dependence

Also Published As

Publication number Publication date
ZA201005630B (en) 2011-08-31
WO2009087578A2 (en) 2009-07-16
CA2711703A1 (en) 2009-07-16

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