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WO2008145708A3 - Aromatic alcohols for the treatment of a biological sample - Google Patents

Aromatic alcohols for the treatment of a biological sample Download PDF

Info

Publication number
WO2008145708A3
WO2008145708A3 PCT/EP2008/056644 EP2008056644W WO2008145708A3 WO 2008145708 A3 WO2008145708 A3 WO 2008145708A3 EP 2008056644 W EP2008056644 W EP 2008056644W WO 2008145708 A3 WO2008145708 A3 WO 2008145708A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological sample
treatment
aromatic alcohols
aromatic alcohol
conservation
Prior art date
Application number
PCT/EP2008/056644
Other languages
German (de)
French (fr)
Other versions
WO2008145708A2 (en
Inventor
Vera Hollaender
Original Assignee
Qiagen Gmbh
Vera Hollaender
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen Gmbh, Vera Hollaender filed Critical Qiagen Gmbh
Publication of WO2008145708A2 publication Critical patent/WO2008145708A2/en
Publication of WO2008145708A3 publication Critical patent/WO2008145708A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a method for the treatment, particularly for the stabilization and/or conservation, of a biological sample, comprising the process steps: i) providing a biological sample, and ii) bringing the biological sample into contact with a composition of (a) 1 to 90 wt.-% of at least one aromatic alcohol, (b) 10 to 99 wt.-% of at least one solvent different from an aromatic alcohol, and (c) 0 to 89 wt.-% of at least one additive different from components (a) and (b), wherein the total amount of components (a) to (c) equals 100 wt.-%. The invention further relates to a method for the treatment, particularly for the stabilization and/or conservation, of a biological sample, to the treated biological sample obtained by said method, to the use of an aromatic alcohol, to the use of a composition, and to a kit.
PCT/EP2008/056644 2007-05-31 2008-05-29 Aromatic alcohols for the treatment of a biological sample WO2008145708A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200710025276 DE102007025276A1 (en) 2007-05-31 2007-05-31 Aromatic alcohols for the treatment of a biological sample
DE102007025276.7 2007-05-31

Publications (2)

Publication Number Publication Date
WO2008145708A2 WO2008145708A2 (en) 2008-12-04
WO2008145708A3 true WO2008145708A3 (en) 2009-01-29

Family

ID=39650487

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/056644 WO2008145708A2 (en) 2007-05-31 2008-05-29 Aromatic alcohols for the treatment of a biological sample

Country Status (2)

Country Link
DE (1) DE102007025276A1 (en)
WO (1) WO2008145708A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022134188B3 (en) 2022-12-20 2024-03-28 Universität Augsburg - Körperschaft des öffentlichen Rechts Method for in-situ recording of changes in a lipid system during storage at a storage temperature below -60 °C

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0215533A2 (en) * 1985-01-18 1987-03-25 Applied Biosystems, Inc. A method of extracting nucleic acids from cells
WO2001018186A1 (en) * 1999-09-10 2001-03-15 New England Biolabs, Inc. A NOVEL TYPE II RESTRICTION ENDONUCLEASE, Hpy188I, OBTAINABLE FROM HELICOBACTER PYLORI J188 AND A PROCESS FOR PRODUCING THE SAME
WO2003095974A2 (en) * 2002-05-07 2003-11-20 Becton, Dickinson And Company Collection assembly
WO2004106547A2 (en) * 2003-06-02 2004-12-09 Check-Points Bv Fast method for detecting micro-organisms in food samples
US20050262582A1 (en) * 2004-03-23 2005-11-24 Nordine Cheikh Promoter molecules for use in plants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU571979B2 (en) 1984-07-06 1988-04-28 Ciba-Geigy Ag Ionically modified polysaccharides
US5300545A (en) 1987-08-12 1994-04-05 Elf Atochem North America, Inc. Process for stabilizing polymer compositions against heat or light effects
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
DE10031236A1 (en) 2000-06-27 2002-01-10 Qiagen Gmbh Use of carboxylic acids and other additives in combination with cationic compounds to stabilize nucleic acids in biological materials
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
EP1450952B1 (en) 2001-10-12 2016-09-21 Becton, Dickinson and Company Apparatus for storing biological samples
US6899850B2 (en) 2001-10-12 2005-05-31 Becton, Dickinson And Company Method and basket apparatus for transporting biological samples
US7517697B2 (en) 2003-02-05 2009-04-14 Applied Biosystems, Llc Compositions and methods for preserving RNA in biological samples
EP2186567A1 (en) 2003-08-05 2010-05-19 Becton, Dickinson and Company Device and methods for collection of biological fluidsample and treatment of selected components
US20050160701A1 (en) 2003-12-24 2005-07-28 Stevens Timothy A. Tissue preservation assembly and method of making and using the same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0215533A2 (en) * 1985-01-18 1987-03-25 Applied Biosystems, Inc. A method of extracting nucleic acids from cells
WO2001018186A1 (en) * 1999-09-10 2001-03-15 New England Biolabs, Inc. A NOVEL TYPE II RESTRICTION ENDONUCLEASE, Hpy188I, OBTAINABLE FROM HELICOBACTER PYLORI J188 AND A PROCESS FOR PRODUCING THE SAME
WO2003095974A2 (en) * 2002-05-07 2003-11-20 Becton, Dickinson And Company Collection assembly
WO2004106547A2 (en) * 2003-06-02 2004-12-09 Check-Points Bv Fast method for detecting micro-organisms in food samples
US20050262582A1 (en) * 2004-03-23 2005-11-24 Nordine Cheikh Promoter molecules for use in plants

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
POLLOCK R E ET AL: "Enhanced MDM2 Oncoprotein Expression in Soft Tissue Sarcoma: Several Possible Regulatory Mechanisms.", SARCOMA 1997, vol. 1, no. 1, 1997, pages 23 - 29, XP002490895, ISSN: 1357-714X *

Also Published As

Publication number Publication date
DE102007025276A1 (en) 2008-12-04
WO2008145708A2 (en) 2008-12-04

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