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WO2007106686A3 - Medical apparatus and method for homogenous aerosol creation - Google Patents

Medical apparatus and method for homogenous aerosol creation Download PDF

Info

Publication number
WO2007106686A3
WO2007106686A3 PCT/US2007/063451 US2007063451W WO2007106686A3 WO 2007106686 A3 WO2007106686 A3 WO 2007106686A3 US 2007063451 W US2007063451 W US 2007063451W WO 2007106686 A3 WO2007106686 A3 WO 2007106686A3
Authority
WO
WIPO (PCT)
Prior art keywords
aerosol
inlet
air
main axis
airway
Prior art date
Application number
PCT/US2007/063451
Other languages
French (fr)
Other versions
WO2007106686A2 (en
Inventor
Wiwik Watanabe
Henning Graaskov
Robert L Clark
Victor P Burolla
Johan Waldeck
Boris N Valentin
Original Assignee
Novo Nordisk As
Wiwik Watanabe
Henning Graaskov
Robert L Clark
Victor P Burolla
Johan Waldeck
Boris N Valentin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As, Wiwik Watanabe, Henning Graaskov, Robert L Clark, Victor P Burolla, Johan Waldeck, Boris N Valentin filed Critical Novo Nordisk As
Publication of WO2007106686A2 publication Critical patent/WO2007106686A2/en
Publication of WO2007106686A3 publication Critical patent/WO2007106686A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1075—Preparation of respiratory gases or vapours by influencing the temperature
    • A61M16/108—Preparation of respiratory gases or vapours by influencing the temperature before being humidified or mixed with a beneficial agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/11—Laminar flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention provides an airway for an inhaler, comprising (a) a tubular airway portion defining a main axis and having an interior, an inlet end and an outlet end, (b) an aerosol inlet arranged at the inlet end, the airway allowing a substantially unimpeded flow along the main axis for an aerosol introduced through the aerosol inlet, and (c) air inlet means arranged in the vicinity of the distal end, wherein (d) the air inlet means is arranged to cause swirling of air introduced there through, the swirl having an axis generally along the main axis. By this arrangement a mixed swirl of air and aerosol is formed whereby the residence time of the aerosol can be prolonged which typically has a beneficial effect on creating small, fine aerosol particles, which usually results in better deposition into deep lung tissue.
PCT/US2007/063451 2006-03-10 2007-03-07 Medical apparatus and method for homogenous aerosol creation WO2007106686A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78232306P 2006-03-10 2006-03-10
US60/782,323 2006-03-10
EP06112150.5 2006-04-03
EP06112150 2006-04-03

Publications (2)

Publication Number Publication Date
WO2007106686A2 WO2007106686A2 (en) 2007-09-20
WO2007106686A3 true WO2007106686A3 (en) 2008-11-27

Family

ID=38510162

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/063451 WO2007106686A2 (en) 2006-03-10 2007-03-07 Medical apparatus and method for homogenous aerosol creation

Country Status (1)

Country Link
WO (1) WO2007106686A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2230934E (en) 2007-12-14 2012-11-20 Aerodesigns Inc Delivering aerosolizable food products
GB2536421A (en) * 2015-03-11 2016-09-21 Linde Ag A device for atomising a liquid
CN106334468A (en) * 2015-07-16 2017-01-18 北京慧荣和科技有限公司 Vortex scattering diluter and exposure apparatus
KR102446255B1 (en) * 2018-01-23 2022-09-22 에스에이치엘 메디컬 아게 aerosol generator
CN114403510A (en) * 2021-12-21 2022-04-29 深圳市吉迩科技有限公司 Gas circuit subassembly and aerosol generating device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6167880B1 (en) * 1993-01-29 2001-01-02 Aradigm Corporation Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume
US20040250812A1 (en) * 1990-03-02 2004-12-16 Davies Michael Birsha Inhalation device
WO2005115520A1 (en) * 2004-05-20 2005-12-08 Discovery Laboratories, Inc. Methods , systems and devices for noninvasive pulmonary delivery
US20060289002A1 (en) * 2005-06-24 2006-12-28 Pari Gmbh Spezialisten Fur Effektive Inhalation Inhalation therapy device
WO2007107160A1 (en) * 2006-03-21 2007-09-27 Bang & Olufsen Medicom A/S Inhaler flow channel

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040250812A1 (en) * 1990-03-02 2004-12-16 Davies Michael Birsha Inhalation device
US6167880B1 (en) * 1993-01-29 2001-01-02 Aradigm Corporation Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume
WO2005115520A1 (en) * 2004-05-20 2005-12-08 Discovery Laboratories, Inc. Methods , systems and devices for noninvasive pulmonary delivery
US20060289002A1 (en) * 2005-06-24 2006-12-28 Pari Gmbh Spezialisten Fur Effektive Inhalation Inhalation therapy device
WO2007107160A1 (en) * 2006-03-21 2007-09-27 Bang & Olufsen Medicom A/S Inhaler flow channel

Also Published As

Publication number Publication date
WO2007106686A2 (en) 2007-09-20

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