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WO2007017562A1 - Element for blocking the movement of a mesh structure serving as a prosthesis - Google Patents

Element for blocking the movement of a mesh structure serving as a prosthesis Download PDF

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Publication number
WO2007017562A1
WO2007017562A1 PCT/FR2005/050650 FR2005050650W WO2007017562A1 WO 2007017562 A1 WO2007017562 A1 WO 2007017562A1 FR 2005050650 W FR2005050650 W FR 2005050650W WO 2007017562 A1 WO2007017562 A1 WO 2007017562A1
Authority
WO
WIPO (PCT)
Prior art keywords
tube
wire
mesh structure
impaction
prosthesis
Prior art date
Application number
PCT/FR2005/050650
Other languages
French (fr)
Inventor
Olivier Cuilleron
Bernard Pain
Original Assignee
Microval
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microval filed Critical Microval
Priority to PCT/FR2005/050650 priority Critical patent/WO2007017562A1/en
Publication of WO2007017562A1 publication Critical patent/WO2007017562A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/064—Surgical staples, i.e. penetrating the tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/869—Pins or screws or threaded wires; nuts therefor characterised by an open form, e.g. wire helix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00867—Material properties shape memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A61B2017/06171—Sutures helically or spirally coiled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/064—Surgical staples, i.e. penetrating the tissue
    • A61B2017/0649—Coils or spirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes

Definitions

  • the invention relates to the technical field of plates in the form of a mesh structure of prosthetic material.
  • prosthesis made for example from a knit or fabric prosthetic material, is well known to those skilled in the art.
  • these prostheses can be used for the inguinal region and intended for the repair of inguinal hernias laparoscopically or openly.
  • the invention relates to the fixation of prosthetic plates at the part of the anatomy considered with a view notably to immobilizing them.
  • a suture may be used.
  • This solution however requires the operator a great dexterity.
  • mechanical suture elements in the form of a pin having a head with a spiral-shaped rod.
  • these fasteners are made of a resorbable material.
  • plastic staples having a substantially I-shaped cross section. Given the nature of the material used, problems can sometimes occur at the fixation when the prosthetic element must be fixed in anatomical parts that have a certain hardness.
  • the object of the invention is to remedy these disadvantages in a simple, safe, efficient and rational manner.
  • the problem to be solved by the invention is to allow the fixation of the prosthetic plate while waiting for the rehabilitation of the prosthetic anatomical parts, without requiring great dexterity, by simply exerting a support force at the level of the fixation zones considered. while aiming to reduce manufacturing costs.
  • an immobilizing element of a mesh structure acting as a prosthesis which is made from a preformed wire to: - constitute at least one turn at rest, c that is to say without any solicitation;
  • the wire is made of a shape memory material.
  • At least one end of the wire is sharpened.
  • FIG. 1 is an exemplary embodiment of the immobilization element according to the invention
  • - Figure 2 shows the immobilizing element obtained from a wire having a plurality of turns, and arranged linearly inside a tube for the establishment of said elements;
  • FIG. 3 is a schematic perspective view showing the attachment of a prosthetic plate by means of the elements according to the invention.
  • FIG. 4 is a sectional view on a large scale and schematic showing the attachment of the prosthetic plate on an anatomical part.
  • the invention finds a particularly advantageous application for the immobilization of a prosthetic plate (1) made from a mesh structure.
  • the prosthetic plate (1) can be obtained by any known and appropriate means, be made of different materials and have different embodiments depending on the nature of the anatomical parts to repair and / or strengthen. This type of prosthesis is well known to a person skilled in the art, and does not form part of the specific object of the invention. The problem is to ensure the immobilization of the prosthetic plate (1) in the thickness of the anatomical part considered (2).
  • the immobilizing element is made from a wire (3) shaped to form at least one turn (3a) in the rest state, that is to say say without any solicitation.
  • the wire (3) is made of a selected material to be developed linearly after introduction into a tube (4) to resume its original shape at the exit of the tube, that is to say present one or more turns ( Figure 2) .
  • the wire (3) is advantageously made in a shape memory material.
  • the bore (4a) of the tube (4) is determined so that after introduction of the wire (3), the or turns is (s) in the stretched state so as to be deployed (s) linearly.
  • wires (3) constituting at least one turn (3a) are arranged in alignment (in the deployed state) in the tube (4) which has means capable of ensuring the thrust of a wire outside said tube at the time of its impaction in the mesh structure (1).
  • the immobilizing element is in the form of a wire (3) having a plurality of turns (3a).
  • This wire is introduced into the bore of the tube (4), so that the different turns are stretched linearly.
  • the tube (4) has means (5) adapted to ensure the thrust of the wire (3) outside said tube for impaction in the anatomical part through the meshes of the prosthetic plate (1).
  • the tube (2) may have cutting means (6) capable of cutting the wire (3) to a given length after impaction.
  • the wire (3) is made of a shape memory material, that at least one of its ends can be sharpened to facilitate insertion.
  • the wire (3) in another material capable of performing the same functions as a shape memory material.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

The invention relates to a movement-blocking assembly comprising a pre-formed wire (3) and a tube (4). According to the invention, the aforementioned wire can: form at least one turn (3a) at rest, i.e. without being biased; be extended linearly following insertion in the tube (4); and take on the original shape thereof upon leaving the tube (4), thereby forming at least one turn in part of the thickness of the anatomical part and through several meshes of the structure in order to form a link.

Description

ELEMENT D'IMMOBILISATION D'UNE STRUCTURE MAILLEE FAISANT OFFICE DE PROTHESE. IMMUNIZATION ELEMENT OF A MESH STRUCTURE PROVIDING PROSTHESIS.
L'invention se rattache au domaine technique des plaques sous forme d'une structure maillée en matériau prothétique.The invention relates to the technical field of plates in the form of a mesh structure of prosthetic material.
Ce type de prothèse réalisé par exemple à partir d'un tricot ou d'un tissu en matériau prothétique, est parfaitement connu de l'homme du métier. A titre indicatif, nullement limitatif, ces prothèses peuvent être utilisées pour la région inguinale et destinées à la réparation de hernies inguinales par voie laparoscopique ou ouverte. Plus particulièrement, l'invention concerne la fixation de plaques prothétiques au niveau de la partie de l'anatomie considérée en vue, notamment, de les immobiliser.This type of prosthesis made for example from a knit or fabric prosthetic material, is well known to those skilled in the art. As an indication, in no way limiting, these prostheses can be used for the inguinal region and intended for the repair of inguinal hernias laparoscopically or openly. More particularly, the invention relates to the fixation of prosthetic plates at the part of the anatomy considered with a view notably to immobilizing them.
Différentes solutions techniques ont été proposées pour obtenir ce résultat. Par exemple, on peut utiliser un fil de suture. Cette solution demande toutefois de la part de l'opérateur une grande dextérité. On connaît également des éléments de suture mécanique sous forme d'un pion présentant une tête avec une tige en forme de spirale. Généralement, ces éléments de fixation sont réalisés dans un matériau résorbable.Various technical solutions have been proposed to obtain this result. For example, a suture may be used. This solution however requires the operator a great dexterity. Also known are mechanical suture elements in the form of a pin having a head with a spiral-shaped rod. Generally, these fasteners are made of a resorbable material.
On connaît également les agrafes en matière plastique présentant une section transversale sensiblement en forme de I. Compte tenu de la nature du matériau utilisé, des problèmes peuvent parfois apparaître au niveau de la fixation lorsque l'élément prothétique doit être fixé dans des parties anatomiques qui ont une certaine dureté.Also known plastic staples having a substantially I-shaped cross section. Given the nature of the material used, problems can sometimes occur at the fixation when the prosthetic element must be fixed in anatomical parts that have a certain hardness.
L'invention s'est fixée pour but de remédier à ces inconvénients, d'une manière simple, sûre, efficace et rationnelle. Le problème que se propose de résoudre l'invention est de permettre la fixation de la plaque prothétique en attente de la réhabilitation des parties anatomiques prothésées, sans demander une grande dextérité, en exerçant simplement un effort d'appui au niveau des zones de fixation considérées, tout en ayant pour objectif de diminuer les coûts de fabrication.The object of the invention is to remedy these disadvantages in a simple, safe, efficient and rational manner. The problem to be solved by the invention is to allow the fixation of the prosthetic plate while waiting for the rehabilitation of the prosthetic anatomical parts, without requiring great dexterity, by simply exerting a support force at the level of the fixation zones considered. while aiming to reduce manufacturing costs.
Pour résoudre un tel problème, il a été conçu un élément d'immobilisation d'une structure maillée faisant office de prothèse, qui est réalisé à partir d'un fil préformé pour : - constituer au moins une spire à l'état repos, c'est-à-dire sans aucune sollicitation ;To solve such a problem, it has been designed an immobilizing element of a mesh structure acting as a prosthesis, which is made from a preformed wire to: - constitute at least one turn at rest, c that is to say without any solicitation;
- être développé linéairement après introduction dans un tube ;- be developed linearly after introduction into a tube;
- reprendre sa forme initiale à la sortie du tube.- return to its original shape at the exit of the tube.
Dans une forme de réalisation préférée, le fil est réalisé dans un matériau à mémoire de forme.In a preferred embodiment, the wire is made of a shape memory material.
Pour résoudre le problème posé de faciliter l'impaction de l'élément d'immobilisation de la partie anatomique considérée, l'une des extrémités au moins du fil est affûtée.To solve the problem of facilitating the impaction of the immobilizing element of the anatomical part considered, at least one end of the wire is sharpened.
A partir de cette conception de base, pour résoudre le problème posé de la mise en place de l'élément d'immobilisation selon les caractéristiques de l'invention, au-travers de la plaque prothétique maillée, plusieurs fils sont disposés en alignement dans le tube qui présente des moyens aptes à assurer l'extraction d'un fil en dehors dudit tube au moment de son impaction dans la structure maillée. Dans une autre forme de réalisation, un fil présentant une pluralité de spires est introduit dans le tube qui présente des moyens aptes à assurer son débordement en dehors dudit tube en vue de l'impaction et des moyens de coupe dudit fil à une longueur déterminée après impaction.From this basic design, to solve the problem of placing the immobilizing element according to the features of the invention, through the meshed prosthetic plate, several son are arranged in alignment in the tube which has means capable of ensuring the extraction of a wire outside said tube at the time of its impaction in the mesh structure. In another embodiment, a wire having a plurality of turns is introduced into the tube which has means capable of ensuring its overflow outside said tube for the purpose of impaction and means for cutting said wire to a length determined after impaction.
L'invention est exposée ci-après plus en détail à l'aide des figures des dessins annexés dans lesquels :The invention is described below in more detail with reference to the figures of the accompanying drawings, in which:
- la figure 1 est un exemple de réalisation de l'élément d'immobilisation selon l'invention ; - la figure 2 montre l'élément d'immobilisation obtenu à partir d'un fil présentant une pluralité de spires, et disposés linéairement à l'intérieur d'un tube pour la mise en place desdits éléments ;FIG. 1 is an exemplary embodiment of the immobilization element according to the invention; - Figure 2 shows the immobilizing element obtained from a wire having a plurality of turns, and arranged linearly inside a tube for the establishment of said elements;
- la figure 3 est une vue en perspective à caractère schématique montrant la fixation d'une plaque prothétique au moyen des éléments selon l'invention ;FIG. 3 is a schematic perspective view showing the attachment of a prosthetic plate by means of the elements according to the invention;
- la figure 4 est une vue en coupe à grande échelle et à caractère schématique montrant la fixation de la plaque prothétique sur une partie anatomique.- Figure 4 is a sectional view on a large scale and schematic showing the attachment of the prosthetic plate on an anatomical part.
Comme indiqué, l'invention trouve une application particulièrement avantageuse pour l'immobilisation d'une plaque prothétique (1) réalisée à partir d'une structure maillée. La plaque prothétique (1) peut être obtenue par tout moyen connu et approprié, être réalisée en différents matériaux et présenter différentes formes de réalisations en fonction de la nature des parties anatomiques à réparer et/ou renforcer. Ce type de prothèse est parfaitement connu pour un homme du métier, et ne fait partie de l'objet spécifique de l'invention. Le problème posé est d'assurer l'immobilisation de la plaque prothétique (1) dans l'épaisseur de la partie anatomique considérée (2).As indicated, the invention finds a particularly advantageous application for the immobilization of a prosthetic plate (1) made from a mesh structure. The prosthetic plate (1) can be obtained by any known and appropriate means, be made of different materials and have different embodiments depending on the nature of the anatomical parts to repair and / or strengthen. This type of prosthesis is well known to a person skilled in the art, and does not form part of the specific object of the invention. The problem is to ensure the immobilization of the prosthetic plate (1) in the thickness of the anatomical part considered (2).
Selon une caractéristique à la base de l'invention, l'élément d'immobilisation est réalisé à partir d'un fil (3) conformé pour constituer au moins une spire (3a) à l'état repos, c'est-à-dire sans aucune sollicitation. Le fil (3) est réalisé dans un matériau sélectionné pour être développé linéairement après introduction dans un tube (4) pour reprendre sa forme initiale à la sortie du tube, c'est-à-dire présenter une ou des spires (figure 2). Pour obtenir ce résultat, le fil (3) est avantageusement réalisé dans un matériau à mémoire de forme.According to a characteristic underlying the invention, the immobilizing element is made from a wire (3) shaped to form at least one turn (3a) in the rest state, that is to say say without any solicitation. The wire (3) is made of a selected material to be developed linearly after introduction into a tube (4) to resume its original shape at the exit of the tube, that is to say present one or more turns (Figure 2) . To obtain this result, the wire (3) is advantageously made in a shape memory material.
L'alésage (4a) du tube (4) est déterminé pour qu'après introduction du fil (3), la ou les spires se trouve(nt) à l'état étiré de manière à être déployée(s) linéairement.The bore (4a) of the tube (4) is determined so that after introduction of the wire (3), the or turns is (s) in the stretched state so as to be deployed (s) linearly.
A partir de cette conception de base, plusieurs formes de réalisation peuvent être envisagées.From this basic design, several embodiments can be envisaged.
Par exemple, plusieurs fils (3), constituant au moins une spire (3a), sont disposés en alignement (à l'état déployé) dans le tube (4) qui présente des moyens aptes à assurer la poussée d'un fil en dehors dudit tube au moment de son impaction dans la structure maillée (1).For example, several wires (3) constituting at least one turn (3a), are arranged in alignment (in the deployed state) in the tube (4) which has means capable of ensuring the thrust of a wire outside said tube at the time of its impaction in the mesh structure (1).
Selon une autre forme de réalisation, comme illustré schématiquement à la figure 2, l'élément d'immobilisation se présente sous forme d'un fil (3) présentant une pluralité de spires (3a). Ce fil est introduit dans l'alésage du tube (4), de sorte que les différentes spires sont étirées linéairement. A l'une des extrémités, le tube (4) présente des moyens (5) aptes à assurer la poussée du fil (3) en dehors dudit tube en vue de son impaction dans la partie anatomique au-travers des mailles de la plaque prothétique (1). A l'autre extrémité, le tube (2) peut présenter des moyens de coupe (6) aptes à assurer la coupe du fil (3) à une longueur déterminée après impaction.According to another embodiment, as diagrammatically illustrated in FIG. 2, the immobilizing element is in the form of a wire (3) having a plurality of turns (3a). This wire is introduced into the bore of the tube (4), so that the different turns are stretched linearly. In one ends, the tube (4) has means (5) adapted to ensure the thrust of the wire (3) outside said tube for impaction in the anatomical part through the meshes of the prosthetic plate (1). At the other end, the tube (2) may have cutting means (6) capable of cutting the wire (3) to a given length after impaction.
Il suffit donc d'exercer, au moyen du tube (4) par exemple, un effort de poussée sur le fil (3) pour permettre son impaction au-travers des mailles de la plaque prothétique (1) dans l'épaisseur de la partie anatomique correspondante (2). D'une manière concomitante, à la libération du fil, il y a formation d'au moins une spire résultant du matériau constitutif dudit fil. La formation de cette spire qui s'effectue dans une partie de l'épaisseur de la partie anatomique (2) et au-travers de plusieurs mailles de la plaque prothétique (1), assure une liaison de ladite plaque par rapport à la partie anatomique considérée (figures 3 et 4).It is therefore sufficient to exert, by means of the tube (4) for example, a pushing force on the wire (3) to allow its impaction through the meshes of the prosthetic plate (1) in the thickness of the part corresponding anatomical (2). Concomitantly, at the release of the wire, there is formation of at least one turn resulting from the material constituting said wire. The formation of this turn which takes place in part of the thickness of the anatomical part (2) and through several meshes of the prosthetic plate (1), ensures a connection of said plate with respect to the anatomical part considered (Figures 3 and 4).
On peut noter, lorsque le fil (3) est réalisé dans un matériau à mémoire de forme, que l'une de ses extrémités au moins, peut être affûtée pour faciliter l'introduction.It may be noted, when the wire (3) is made of a shape memory material, that at least one of its ends can be sharpened to facilitate insertion.
Sans pour cela sortir du cadre de l'invention, on n'exclut pas de réaliser le fil (3) dans un autre matériau apte à remplir les mêmes fonctions qu'un matériau à mémoire de forme.Without departing from the scope of the invention, it is not excluded to make the wire (3) in another material capable of performing the same functions as a shape memory material.
Les avantages ressortent bien de la description. The advantages are apparent from the description.

Claims

R E V E N D I C A T I O N S R E V E N D I C A T IO N S
-1- Ensemble d'immobilisation d'une structure maillée faisant office de prothèse, sur une partie anatomique, caractérisé en ce qu'il comprend un fil préformé (3) et un tube (4), ledit fil étant apte à :-1- immobilizing assembly of a mesh structure acting as a prosthesis, on an anatomical part, characterized in that it comprises a preformed wire (3) and a tube (4), said wire being able to:
- constituer au moins une spire (3a) à l'état repos, c'est-à-dire sans aucune sollicitation ;- To constitute at least one turn (3a) in the rest state, that is to say without any solicitation;
- être développé linéairement après introduction dans le tube (4) ; - reprendre sa forme initiale à la sortie du tube (4), en constituant au moins une spire réalisée dans une partie de l'épaisseur de la partie anatomique et au-travers de plusieurs mailles de la structure pour assurer une liaison.- be developed linearly after introduction into the tube (4); - Return to its original shape at the exit of the tube (4), by constituting at least one turn made in part of the thickness of the anatomical part and through several meshes of the structure to provide a connection.
-2- Ensemble selon la revendication 1, caractérisé en ce que le fil (3) est réalisé dans un matériau à mémoire de forme.-2- assembly according to claim 1, characterized in that the wire (3) is made of a shape memory material.
-3- Ensemble selon la revendication 1, caractérisé en ce que l'une des extrémités au moins du fil est affûtée.Assembly according to claim 1, characterized in that at least one end of the wire is sharpened.
-4- Ensemble selon la revendication 1, caractérisé en ce que le tube (4) présente des moyens aptes à assurer l'extraction d'un fil en dehors dudit tube au moment de son impaction dans la structure maillée, plusieurs fils étant disposés en alignement dans ledit tube.-4- assembly according to claim 1, characterized in that the tube (4) has means for ensuring the extraction of a wire outside said tube at the time of its impaction in the mesh structure, several son being arranged in alignment in said tube.
-5- Ensemble selon la revendication 1, caractérisé en ce que le tube (4) présente des moyens (5) aptes à assurer le débordement d'un fil présentant une pluralité de spires en dehors dudit tube en vue de l'impaction et des moyens de coupe (6) dudit fil, à une longueur déterminée, après impaction. -5- The assembly of claim 1, characterized in that the tube (4) has means (5) adapted to ensure the overflow of a wire having a plurality of turns outside said tube for the impaction and the cutting means (6) of said wire, at a determined length, after impaction.
PCT/FR2005/050650 2005-08-04 2005-08-04 Element for blocking the movement of a mesh structure serving as a prosthesis WO2007017562A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/FR2005/050650 WO2007017562A1 (en) 2005-08-04 2005-08-04 Element for blocking the movement of a mesh structure serving as a prosthesis

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Cited By (4)

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Publication number Priority date Publication date Assignee Title
FR2924917A1 (en) * 2007-12-13 2009-06-19 Microval Sa APPARATUS FOR INSTALLING SUTURE SPIERS RESULTING FROM A SHAPE MEMORY METAL WIRE.
WO2014042600A3 (en) * 2012-09-17 2014-05-08 Babala Jozef Shaped surgical thread for intracorporal knotting and method of production
WO2014178869A1 (en) * 2013-05-02 2014-11-06 Empire Technology Development Llc Diverticulum treating device
US10400233B2 (en) 2014-03-31 2019-09-03 Roche Diabetes Care, Inc. High load enzyme immobilization by crosslinking

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