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WO2006105843A3 - Method for producing rhamnose and aglycones by splitting rutinosides using yeast - Google Patents

Method for producing rhamnose and aglycones by splitting rutinosides using yeast Download PDF

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Publication number
WO2006105843A3
WO2006105843A3 PCT/EP2006/002118 EP2006002118W WO2006105843A3 WO 2006105843 A3 WO2006105843 A3 WO 2006105843A3 EP 2006002118 W EP2006002118 W EP 2006002118W WO 2006105843 A3 WO2006105843 A3 WO 2006105843A3
Authority
WO
WIPO (PCT)
Prior art keywords
yeast
rutinosides
splitting
aglycones
rhamnose
Prior art date
Application number
PCT/EP2006/002118
Other languages
German (de)
French (fr)
Other versions
WO2006105843A2 (en
Inventor
Corinna Wirth
Sylvia Huber
Herwig Buchholz
Original Assignee
Merck Patent Gmbh
Corinna Wirth
Sylvia Huber
Herwig Buchholz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh, Corinna Wirth, Sylvia Huber, Herwig Buchholz filed Critical Merck Patent Gmbh
Publication of WO2006105843A2 publication Critical patent/WO2006105843A2/en
Publication of WO2006105843A3 publication Critical patent/WO2006105843A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/02Monosaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a method for splitting rutinosides in order to obtain rhamnose and/or the corresponding aglycones. Said method is characterised in that the reaction is carried out in the presence of yeast. The invention also relates to the corresponding use of yeast.
PCT/EP2006/002118 2005-04-05 2006-03-08 Method for producing rhamnose and aglycones by splitting rutinosides using yeast WO2006105843A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005015447.6 2005-04-05
DE200510015447 DE102005015447A1 (en) 2005-04-05 2005-04-05 Process for the cleavage of rutinosides

Publications (2)

Publication Number Publication Date
WO2006105843A2 WO2006105843A2 (en) 2006-10-12
WO2006105843A3 true WO2006105843A3 (en) 2007-03-29

Family

ID=36962007

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/002118 WO2006105843A2 (en) 2005-04-05 2006-03-08 Method for producing rhamnose and aglycones by splitting rutinosides using yeast

Country Status (2)

Country Link
DE (1) DE102005015447A1 (en)
WO (1) WO2006105843A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104130299B (en) * 2014-07-01 2016-06-22 昆明理工大学 The extraction separation method of rhamnetin-3-O-β-D-6-O-.alpha.-L-rhamnosyl-D-glucose. in Flos Caraganae Sinicae alabastrum
CN110183405B (en) * 2019-05-30 2021-07-02 苏州禾研生物技术有限公司 Method for preparing quercetin and compound rhamnose syrup by acid hydrolysis of rutin

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000026399A2 (en) * 1998-10-30 2000-05-11 Merck Patent Gmbh Method for the production of quercetin and isoquercetin derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000026399A2 (en) * 1998-10-30 2000-05-11 Merck Patent Gmbh Method for the production of quercetin and isoquercetin derivatives

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MIKLOSY, E. & PÖLÖS, V.: "Yeasts with beta-D-glucosidase activity: properties and possible application in winemaking processes", ACTA ALIMENTARIA, vol. 24, no. 2, 1995, pages 167 - 180, XP008071371 *
WESTLAKE, D.W.S. & SPENCER, J.F.T.: "The utilization of flavonoid compounds by yeasts and yeast-like fungi", CANADIAN JOURNAL OF MICROBIOLOGY, vol. 12, no. 1, 1966, pages 165 - 174, XP008071313 *
YANAI, T. & SATO, M.: "Purification and Characterization of an alpha-L-Rhamnosidase from Pichia angusta X349", BIOSCIENCE BIOTECHNOLOGY BIOCHEMISTRY, vol. 64, no. 10, 2000, pages 2179 - 2185, XP008071309 *

Also Published As

Publication number Publication date
WO2006105843A2 (en) 2006-10-12
DE102005015447A1 (en) 2006-10-12

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