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WO2006069592A3 - Method for diagnosing an/or predicting preeclampsia and/or related disorders - Google Patents

Method for diagnosing an/or predicting preeclampsia and/or related disorders Download PDF

Info

Publication number
WO2006069592A3
WO2006069592A3 PCT/EP2004/014879 EP2004014879W WO2006069592A3 WO 2006069592 A3 WO2006069592 A3 WO 2006069592A3 EP 2004014879 W EP2004014879 W EP 2004014879W WO 2006069592 A3 WO2006069592 A3 WO 2006069592A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnosing
related disorders
predicting
nucleic acid
preeclampsia
Prior art date
Application number
PCT/EP2004/014879
Other languages
French (fr)
Other versions
WO2006069592A2 (en
Inventor
Cornelis Bartholomeus Oudejans
Dijk Marie Van
Joyce Mulders
Original Assignee
Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg
Cornelis Bartholomeus Oudejans
Dijk Marie Van
Joyce Mulders
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg, Cornelis Bartholomeus Oudejans, Dijk Marie Van, Joyce Mulders filed Critical Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg
Priority to PCT/EP2004/014879 priority Critical patent/WO2006069592A2/en
Publication of WO2006069592A2 publication Critical patent/WO2006069592A2/en
Publication of WO2006069592A3 publication Critical patent/WO2006069592A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to methods for predicting and/or diagnosing a pregnancy at risk for preeclampsia and/or related disorders, comprising: (a) obtaining at least one marker nucleic acid from a biological sample; (b) providing the diagnosis based on at least one of the quantity, activity and/or sequence of said marker nucleic acid in said sample. The invention further relates to the marker nucleic acid per se for use in predicting, diagnosing, preventing and/or treating preeclampsia and/or related disorders, as well as to kits and primers for use in the methods of the invention.
PCT/EP2004/014879 2004-12-31 2004-12-31 Method for diagnosing an/or predicting preeclampsia and/or related disorders WO2006069592A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/EP2004/014879 WO2006069592A2 (en) 2004-12-31 2004-12-31 Method for diagnosing an/or predicting preeclampsia and/or related disorders

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2004/014879 WO2006069592A2 (en) 2004-12-31 2004-12-31 Method for diagnosing an/or predicting preeclampsia and/or related disorders

Publications (2)

Publication Number Publication Date
WO2006069592A2 WO2006069592A2 (en) 2006-07-06
WO2006069592A3 true WO2006069592A3 (en) 2008-01-03

Family

ID=34960411

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/014879 WO2006069592A2 (en) 2004-12-31 2004-12-31 Method for diagnosing an/or predicting preeclampsia and/or related disorders

Country Status (1)

Country Link
WO (1) WO2006069592A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100041026A1 (en) * 2005-06-28 2010-02-18 Majercak John M Method for Identiflying Modulators of Rufy2 Useful for Treating Alzheimer's Disease
US20110237649A1 (en) * 2008-12-04 2011-09-29 Opko Curna, Llc Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirtuin 1
EP2403946A4 (en) * 2009-03-04 2012-11-14 Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirt 1
EP2985348B1 (en) * 2009-07-24 2020-12-30 CuRNA, Inc. Treatment of sirtuin 6 (sirt6) related diseases by inhibition of natural antisense transcript to sirt6

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763168A (en) * 1992-09-30 1998-06-09 University Of Utah Research Foundation Method to determine predisposition to hypertension
WO1999043851A1 (en) * 1998-02-25 1999-09-02 National University Of Ireland, Cork Hla linked pre-eclampsia and miscarriage susceptibility gene
US6177252B1 (en) * 1999-08-27 2001-01-23 University Of Utah Research Foundation Method to determine predisposition to hypertension
WO2001057190A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2002004678A2 (en) * 2000-07-07 2002-01-17 Genetics Institute, Llc. Methods and compositions for diagnosing and treating preeclampsia and gestational trophoblast disorders
US20030219776A1 (en) * 2001-12-18 2003-11-27 Jean-Marc Lalouel Molecular variants, haplotypes and linkage disequilibrium within the human angiotensinogen gene

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763168A (en) * 1992-09-30 1998-06-09 University Of Utah Research Foundation Method to determine predisposition to hypertension
WO1999043851A1 (en) * 1998-02-25 1999-09-02 National University Of Ireland, Cork Hla linked pre-eclampsia and miscarriage susceptibility gene
US6177252B1 (en) * 1999-08-27 2001-01-23 University Of Utah Research Foundation Method to determine predisposition to hypertension
WO2001057190A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2002004678A2 (en) * 2000-07-07 2002-01-17 Genetics Institute, Llc. Methods and compositions for diagnosing and treating preeclampsia and gestational trophoblast disorders
US20030219776A1 (en) * 2001-12-18 2003-11-27 Jean-Marc Lalouel Molecular variants, haplotypes and linkage disequilibrium within the human angiotensinogen gene

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1 August 2004 (2004-08-01), OUDEJANS CEES B M ET AL: "The parent-of-origin effect of 10q22 in pre-eclamptic females coincides with two regions clustered for genes with down-regulated expression in androgenetic placentas", XP002339275, Database accession no. PREV200400354632 *
IRIYAMA CHISAKO ET AL: "Cloning and sequencing of a novel human gene which encodes a putative hydroxylase", JOURNAL OF HUMAN GENETICS, vol. 46, no. 5, 2001, pages 289 - 292, XP002339241, ISSN: 1434-5161 *
MOLECULAR HUMAN REPRODUCTION, vol. 10, no. 8, 1 August 2004 (2004-08-01), pages 589 - 598, ISSN: 1360-9947 *

Also Published As

Publication number Publication date
WO2006069592A2 (en) 2006-07-06

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