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WO2005020880A3 - Methodes de traitement de l'endometriose - Google Patents

Methodes de traitement de l'endometriose Download PDF

Info

Publication number
WO2005020880A3
WO2005020880A3 PCT/IB2004/003103 IB2004003103W WO2005020880A3 WO 2005020880 A3 WO2005020880 A3 WO 2005020880A3 IB 2004003103 W IB2004003103 W IB 2004003103W WO 2005020880 A3 WO2005020880 A3 WO 2005020880A3
Authority
WO
WIPO (PCT)
Prior art keywords
endometriosis
treatment
methods
nodules
administration
Prior art date
Application number
PCT/IB2004/003103
Other languages
English (en)
Other versions
WO2005020880A2 (fr
Inventor
Mirudhubashini Bovindarajan
Original Assignee
Miscon Trading S A
Mirudhubashini Bovindarajan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN2004800252187A priority Critical patent/CN1845723B/zh
Priority to PL04769463T priority patent/PL1660009T3/pl
Application filed by Miscon Trading S A, Mirudhubashini Bovindarajan filed Critical Miscon Trading S A
Priority to ES04769463.3T priority patent/ES2535430T3/es
Priority to EP04769463.3A priority patent/EP1660009B1/fr
Priority to KR1020117031425A priority patent/KR101288265B1/ko
Priority to JP2006525216A priority patent/JP5651279B2/ja
Priority to AU2004267956A priority patent/AU2004267956B2/en
Priority to EA200600524A priority patent/EA015356B1/ru
Priority to CA2537702A priority patent/CA2537702C/fr
Priority to SI200432237T priority patent/SI1660009T1/sl
Priority to BRPI0413200-9A priority patent/BRPI0413200A/pt
Priority to DK04769463.3T priority patent/DK1660009T3/en
Priority to KR1020067004304A priority patent/KR101285137B1/ko
Publication of WO2005020880A2 publication Critical patent/WO2005020880A2/fr
Priority to IL174014A priority patent/IL174014A0/en
Priority to TNP2006000070A priority patent/TNSN06070A1/en
Priority to NO20061502A priority patent/NO20061502L/no
Publication of WO2005020880A3 publication Critical patent/WO2005020880A3/fr
Priority to HK07102652.8A priority patent/HK1095529A1/xx
Priority to HRP20150440TT priority patent/HRP20150440T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Surgical Instruments (AREA)

Abstract

On peut traiter efficacement l'endométriose, y compris l'endométriose externe, les endométriomes, l'adénomyose, les adénomyomes, les nodules adénomyotiques des ligaments utéro-sacrés, et les nodules endométriotiques, tels que l'endométriose sur cicatrice, par administration intralésionnelle, y compris transvaginale, endoscopique ou par une chirurgie ouverte, y compris la laparotomie, d'un progestogène. L'invention concerne également des compositions utilisées à cet effet.
PCT/IB2004/003103 2003-09-03 2004-08-27 Methodes de traitement de l'endometriose WO2005020880A2 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
BRPI0413200-9A BRPI0413200A (pt) 2003-09-03 2004-08-27 método para tratamento de endometriose
SI200432237T SI1660009T1 (sl) 2003-09-03 2004-08-27 Metode za zdravljenje endometrioze
DK04769463.3T DK1660009T3 (en) 2003-09-03 2004-08-27 METHODS OF TREATING ENDOMETRIOSIS
PL04769463T PL1660009T3 (pl) 2003-09-03 2004-08-27 Sposoby leczenia endometriozy
KR1020117031425A KR101288265B1 (ko) 2003-09-03 2004-08-27 자궁 내막증의 치료 방법
JP2006525216A JP5651279B2 (ja) 2003-09-03 2004-08-27 子宮内膜症の処置のための方法
AU2004267956A AU2004267956B2 (en) 2003-09-03 2004-08-27 Methods for the treatment of endometriosis
EA200600524A EA015356B1 (ru) 2003-09-03 2004-08-27 Способы лечения эндометриоза
CA2537702A CA2537702C (fr) 2003-09-03 2004-08-27 Methodes de traitement de l'endometriose
CN2004800252187A CN1845723B (zh) 2003-09-03 2004-08-27 子宫内膜异位症的治疗方法
EP04769463.3A EP1660009B1 (fr) 2003-09-03 2004-08-27 Methodes de traitement de l'endometriose
ES04769463.3T ES2535430T3 (es) 2003-09-03 2004-08-27 Métodos para el tratamiento de la endometriosis
KR1020067004304A KR101285137B1 (ko) 2003-09-03 2004-08-27 자궁 내막증의 치료 방법
IL174014A IL174014A0 (en) 2003-09-03 2006-02-28 Methods for the treatment of endometriosis
TNP2006000070A TNSN06070A1 (en) 2003-09-03 2006-03-01 Methods for the treatment of endometriosis
NO20061502A NO20061502L (no) 2003-09-03 2006-04-03 Fremgangsmate for behandling av endometriose
HK07102652.8A HK1095529A1 (en) 2003-09-03 2007-03-12 Methods for the treatment of endometriosis
HRP20150440TT HRP20150440T1 (hr) 2003-09-03 2015-04-22 Metode za lijeäśenje endometrioze

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50021703P 2003-09-03 2003-09-03
US60/500,217 2003-09-03
US52635503P 2003-12-01 2003-12-01
US60/526,355 2003-12-01

Publications (2)

Publication Number Publication Date
WO2005020880A2 WO2005020880A2 (fr) 2005-03-10
WO2005020880A3 true WO2005020880A3 (fr) 2006-05-26

Family

ID=34278698

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/003103 WO2005020880A2 (fr) 2003-09-03 2004-08-27 Methodes de traitement de l'endometriose

Country Status (22)

Country Link
US (2) US9532995B2 (fr)
EP (2) EP1660009B1 (fr)
JP (2) JP5651279B2 (fr)
KR (2) KR101288265B1 (fr)
CN (1) CN101849906A (fr)
AU (1) AU2004267956B2 (fr)
BR (1) BRPI0413200A (fr)
CA (1) CA2537702C (fr)
DK (1) DK1660009T3 (fr)
EA (1) EA015356B1 (fr)
ES (1) ES2535430T3 (fr)
HK (1) HK1095529A1 (fr)
HR (1) HRP20150440T1 (fr)
HU (1) HUE025239T2 (fr)
IL (1) IL174014A0 (fr)
MA (1) MA28083A1 (fr)
NO (1) NO20061502L (fr)
PL (1) PL1660009T3 (fr)
PT (1) PT1660009E (fr)
SI (1) SI1660009T1 (fr)
TN (1) TNSN06070A1 (fr)
WO (1) WO2005020880A2 (fr)

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WO2009140126A1 (fr) * 2008-05-14 2009-11-19 Juneau Biosciences, Llc Procédé d’administration d’un agent thérapeutique
EP2632346A4 (fr) * 2010-01-05 2015-05-27 Beacon Endoscopic Corp Méthodes et appareil pour anastomose par compression induite magnétiquement entre des organes adjacents
EP2471537A1 (fr) * 2010-12-30 2012-07-04 PregLem S.A. Traitement de la douleur associé à la dislocation de l'endomètre de base
AR082266A1 (es) * 2011-05-13 2012-11-28 Univ Nac Del Litoral Microparticula inyectable de liberacion controlada
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
JP6285866B2 (ja) 2011-11-23 2018-02-28 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然複合ホルモン補充製剤および療法
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015073066A1 (fr) * 2013-11-12 2015-05-21 University Of Utah Research Foundation Hydrogel thermosensible à base de glycol-chitine pour administration de progestérone par voie vaginale
CA2947767A1 (fr) 2014-05-22 2015-11-26 Therapeuticsmd, Inc. Formulations d'hormones substitutives combinees naturelles et traitement hormonal substitutif
AU2015296609A1 (en) 2014-07-29 2016-12-22 Therapeuticsmd, Inc. Transdermal cream
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
JP2019513709A (ja) 2016-04-01 2019-05-30 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． ステロイドホルモン薬学的組成物
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
WO2018063985A1 (fr) * 2016-09-28 2018-04-05 Atossa Genetics Inc. Méthodes de thérapie cellulaire adoptive
RU2661701C1 (ru) * 2017-02-09 2018-07-19 федеральное государственное автономное образовательное учреждение высшего образования "Российский университет дружбы народов" (РУДН) Способ лапароскопического лечения узловых форм аденомиоза
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
US20230057790A1 (en) * 2020-02-26 2023-02-23 Fordoz Pharma Corp. Injectable controlled-release formulations of progestogen drugs
RU2746476C1 (ru) * 2020-04-28 2021-04-14 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) Способ хирургического лечения глубокого инфильтративного эндометриоза ректовагинальной перегородки
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US5362720A (en) * 1991-06-28 1994-11-08 Endorecherche, Inc. Methods of treating or preventing breast or endometrial cancer with low dose non-masculinizing androgenic compounds
US5543150A (en) * 1993-09-15 1996-08-06 Columbia Laboratories, Inc. Method of progesterone delivery and affect thereof
US6225298B1 (en) * 1994-11-22 2001-05-01 Balance Pharmaceuticals, Inc. Compositions and methods for contraception and for treatment of benign gynecological disorders
US6416778B1 (en) * 1997-01-24 2002-07-09 Femmepharma Pharmaceutical preparations and methods for their regional administration

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US4038389A (en) * 1975-05-07 1977-07-26 The Upjohn Company Medroxyprogesterone acetate compositions
US5362720A (en) * 1991-06-28 1994-11-08 Endorecherche, Inc. Methods of treating or preventing breast or endometrial cancer with low dose non-masculinizing androgenic compounds
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Also Published As

Publication number Publication date
KR101288265B1 (ko) 2013-07-26
EP2617411A1 (fr) 2013-07-24
CN101849906A (zh) 2010-10-06
JP2013035866A (ja) 2013-02-21
KR20120005062A (ko) 2012-01-13
CA2537702A1 (fr) 2005-03-10
SI1660009T1 (sl) 2015-07-31
JP5651279B2 (ja) 2015-01-07
EP1660009A2 (fr) 2006-05-31
AU2004267956B2 (en) 2010-09-16
PT1660009E (pt) 2015-05-18
HUE025239T2 (en) 2016-03-29
ES2535430T3 (es) 2015-05-11
EA200600524A1 (ru) 2006-08-25
AU2004267956A1 (en) 2005-03-10
KR101285137B1 (ko) 2013-07-11
MA28083A1 (fr) 2006-08-01
HRP20150440T1 (hr) 2015-07-03
EA015356B1 (ru) 2011-06-30
HK1095529A1 (en) 2007-05-11
DK1660009T3 (en) 2015-04-27
US20050085453A1 (en) 2005-04-21
IL174014A0 (en) 2006-08-01
US9468647B2 (en) 2016-10-18
JP2007509032A (ja) 2007-04-12
NO20061502L (no) 2006-06-02
PL1660009T3 (pl) 2015-08-31
EP1660009B1 (fr) 2015-01-28
BRPI0413200A (pt) 2006-10-03
US9532995B2 (en) 2017-01-03
US20150044291A1 (en) 2015-02-12
KR20070017946A (ko) 2007-02-13
EP1660009A4 (fr) 2010-02-17
WO2005020880A2 (fr) 2005-03-10
CA2537702C (fr) 2012-01-03
TNSN06070A1 (en) 2007-10-03

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