WO2005085867A3 - Screening method for emulators of neural activity and digestive system using gpr35 - Google Patents
Screening method for emulators of neural activity and digestive system using gpr35 Download PDFInfo
- Publication number
- WO2005085867A3 WO2005085867A3 PCT/IB2005/000382 IB2005000382W WO2005085867A3 WO 2005085867 A3 WO2005085867 A3 WO 2005085867A3 IB 2005000382 W IB2005000382 W IB 2005000382W WO 2005085867 A3 WO2005085867 A3 WO 2005085867A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gpr35
- screening method
- receptor
- emulators
- digestive system
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05702505A EP1720530A2 (en) | 2004-02-27 | 2005-02-14 | Screening method for emulators of neural activity and digestive system using gpr35 |
CA002558721A CA2558721A1 (en) | 2004-02-27 | 2005-02-14 | Screening method for emulators of neural activity and digestive system using gpr35 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54871904P | 2004-02-27 | 2004-02-27 | |
US60/548,719 | 2004-02-27 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2005085867A2 WO2005085867A2 (en) | 2005-09-15 |
WO2005085867A3 true WO2005085867A3 (en) | 2006-04-20 |
WO2005085867A8 WO2005085867A8 (en) | 2006-06-22 |
Family
ID=34919394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2005/000382 WO2005085867A2 (en) | 2004-02-27 | 2005-02-14 | Screening method for emulators of neural activity and digestive system using gpr35 |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1720530A2 (en) |
CA (1) | CA2558721A1 (en) |
WO (1) | WO2005085867A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7491699B2 (en) | 2002-12-09 | 2009-02-17 | Ramot At Tel Aviv University Ltd. | Peptide nanostructures and methods of generating and using the same |
WO2006013552A2 (en) | 2004-08-02 | 2006-02-09 | Ramot At Tel Aviv University Ltd. | Articles of peptide nanostructures and method of forming the same |
WO2006018850A2 (en) * | 2004-08-19 | 2006-02-23 | Tel Aviv University Future Technology Development L.P. | Compositions for treating amyloid associated diseases |
US10004828B2 (en) | 2005-10-11 | 2018-06-26 | Romat at Tel-Aviv University Ltd. | Self-assembled Fmoc-ff hydrogels |
US9040583B2 (en) | 2009-07-22 | 2015-05-26 | Temple University-Of The Commonwealth System Of Higher Education | Treatment of disorders associated with G protein-coupled receptor 35 (GPR35) |
US20120022116A1 (en) * | 2010-07-20 | 2012-01-26 | Huayun Deng | Compositions and methods for the treatment of pathological condition(s) related to gpr35 and/or gpr35-herg complex |
WO2020128948A1 (en) * | 2018-12-21 | 2020-06-25 | Glycom A/S | Composition and method for promoting intestinal barrier healing |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999064452A1 (en) * | 1998-06-11 | 1999-12-16 | Smithkline Beecham Corporation | Gpr35a receptor |
WO2000008155A2 (en) * | 1998-08-07 | 2000-02-17 | Incyte Pharmaceuticals, Inc. | Human receptor-associated proteins |
US6403305B1 (en) * | 1997-02-06 | 2002-06-11 | Cornell Research Foundation, Inc. | Methods of identifying peptide agonists or negative antagonists of a G protein coupled receptor |
WO2002059344A2 (en) * | 2000-12-18 | 2002-08-01 | Merck & Co., Inc. | Gpr54 g protein-coupled receptor |
WO2002061087A2 (en) * | 2000-12-19 | 2002-08-08 | Lifespan Biosciences, Inc. | Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides |
WO2004040000A2 (en) * | 2002-09-09 | 2004-05-13 | Nura, Inc | G protein coupled receptors and uses thereof |
-
2005
- 2005-02-14 CA CA002558721A patent/CA2558721A1/en not_active Abandoned
- 2005-02-14 EP EP05702505A patent/EP1720530A2/en not_active Withdrawn
- 2005-02-14 WO PCT/IB2005/000382 patent/WO2005085867A2/en not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6403305B1 (en) * | 1997-02-06 | 2002-06-11 | Cornell Research Foundation, Inc. | Methods of identifying peptide agonists or negative antagonists of a G protein coupled receptor |
WO1999064452A1 (en) * | 1998-06-11 | 1999-12-16 | Smithkline Beecham Corporation | Gpr35a receptor |
WO2000008155A2 (en) * | 1998-08-07 | 2000-02-17 | Incyte Pharmaceuticals, Inc. | Human receptor-associated proteins |
WO2002059344A2 (en) * | 2000-12-18 | 2002-08-01 | Merck & Co., Inc. | Gpr54 g protein-coupled receptor |
WO2002061087A2 (en) * | 2000-12-19 | 2002-08-08 | Lifespan Biosciences, Inc. | Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides |
WO2004040000A2 (en) * | 2002-09-09 | 2004-05-13 | Nura, Inc | G protein coupled receptors and uses thereof |
Non-Patent Citations (7)
Title |
---|
DATABASE EMBL [online] 21 November 2002 (2002-11-21), "Rattus norvegicus clone CH230-unknown, *** SEQUENCING IN PROGRESS ***, 9 unordered pieces.", XP002330589, retrieved from EBI accession no. EM_HTG:AC137209 Database accession no. AC137209 * |
DATABASE Geneseq [online] 11 April 2000 (2000-04-11), "Human G-protein coupled receptor GPR35A.", XP002330409, retrieved from EBI accession no. GSP:AAY58645 Database accession no. AAY58645 * |
DATABASE Geneseq [online] 29 July 2004 (2004-07-29), "Mouse GPCR GPR35, SEQ ID NO:497.", XP002330410, retrieved from EBI accession no. GSP:ADO29395 Database accession no. ADO29395 * |
DATABASE Geneseq [online] 31 May 2000 (2000-05-31), "Human receptor-associated protein from Incyte clone 3083742.", XP002330411, retrieved from EBI accession no. GSP:AAY69989 Database accession no. AAY69989 * |
DATABASE Geneseq [online] 4 March 2003 (2003-03-04), "Human G protein-coupled receptor GPR35 protein SEQ ID NO:492.", XP002330412, retrieved from EBI accession no. GSP:ABP82002 Database accession no. ABP82002 * |
DATABASE UniProt [online] 1 March 2003 (2003-03-01), "Mus musculus adult male bone cDNA, RIKEN full-length enriched library, clone:9830121M19 product:G protein-coupled receptor 35, full insert sequence.", XP002330588, retrieved from EBI accession no. UNIPROT:Q8CB97 Database accession no. Q8CB97 * |
DATABASE UniProt [online] 16 October 2001 (2001-10-16), "Probable G-protein coupled receptor 35.", XP002330587, retrieved from EBI accession no. UNIPROT:GPR35_MOUSE Database accession no. GPR35_MOUSE * |
Also Published As
Publication number | Publication date |
---|---|
WO2005085867A2 (en) | 2005-09-15 |
CA2558721A1 (en) | 2005-09-15 |
EP1720530A2 (en) | 2006-11-15 |
WO2005085867A8 (en) | 2006-06-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2006094704A3 (en) | Natural ligand of g protein coupled receptor rcc356 and uses thereof | |
WO2007092938A3 (en) | Cellular assays for signaling receptors | |
SG11201804563SA (en) | Digital microfluidic system for single-cell isolation and characterization of analytes | |
IL179427A0 (en) | Antibodies as t cell receptor mimics, methods of production and uses thereof | |
WO2009100040A3 (en) | Cell lines expressing gaba receptor and methods using them | |
Hauser et al. | Novel approaches leading towards peptide GPCR de‐orphanisation | |
WO2006002161A3 (en) | Modulators of odorant receptors | |
WO2005085867A8 (en) | Screening method for emulators of neural activity and digestive system using gpr35 | |
WO2009055509A3 (en) | Cholesterol consensus motif of membrane proteins | |
WO2008032217A3 (en) | Method for investigating the response to a treatment with a monoclonal antibody | |
WO2006031883A3 (en) | Analysis of mhc-peptide binding interactions | |
WO2003095606A3 (en) | A t cell subpopulation regulating gut immunity | |
Fan et al. | Collection of peptides released from single neurons with particle-embedded monolithic capillaries followed by detection with matrix-assisted laser desorption/ionization mass spectrometry | |
WO2004037160A3 (en) | In vitro test for studying compound predicting pharmacologic and/or pharmacokinetic and/or pharmacodynamic parameters of a compound | |
WO2007039507A3 (en) | Methods of identifying antibodies to ligands of orphan receptors | |
EP1340979A3 (en) | Neuropeptide receptor and uses thereof | |
WO2004009770A3 (en) | Methods and compositions for modulating agonist-induced downregulation of g protein-coupled receptors | |
WO2001067106A8 (en) | Identification of g protein-coupled receptor ligands and modulators | |
GB0305656D0 (en) | Screening assay | |
AU2003291608A1 (en) | A method of drug screening to select agonists or antagonists of g protein coupled receptors (gpcr). | |
WO2008002656A3 (en) | Methods and materials for in vitro analysis and/or use of membrane-associated proteins, portions thereof or variants thereof | |
WO2007089899A3 (en) | Water-soluble (g protein)-coupled receptor protein | |
WO2005119230A3 (en) | Pharmacophores for nociceptin, methods of obtaining and using in screening for nociceptin mimics | |
CA2390914A1 (en) | A method for expressing a functional membrane-bound receptor protein using budded baculovirus | |
DK1317564T3 (en) | Screening Methods to Identify G Proteins and Other Compounds That Modulate Phosphodiesterase (PDE) Activity |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
DPEN | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
CFP | Corrected version of a pamphlet front page |
Free format text: UNDER (54) PUBLISHED TITLE REPLACED BY CORRECT TITLE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2558721 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2005702505 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/2006/009534 Country of ref document: MX |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2007500310 Country of ref document: JP |
|
WWP | Wipo information: published in national office |
Ref document number: 2005702505 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref document number: PI0508011 Country of ref document: BR |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 2005702505 Country of ref document: EP |