[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

WO2004091542A3 - Nitrogen containing integrin targeting compounds - Google Patents

Nitrogen containing integrin targeting compounds Download PDF

Info

Publication number
WO2004091542A3
WO2004091542A3 PCT/US2004/012034 US2004012034W WO2004091542A3 WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3 US 2004012034 W US2004012034 W US 2004012034W WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3
Authority
WO
WIPO (PCT)
Prior art keywords
integrin targeting
nitrogen containing
targeting compounds
containing integrin
compounds
Prior art date
Application number
PCT/US2004/012034
Other languages
French (fr)
Other versions
WO2004091542A2 (en
Inventor
Amir Tamiz
Curt W Bradshaw
Original Assignee
Covx Pharmaceuticals Inc
Amir Tamiz
Curt W Bradshaw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Covx Pharmaceuticals Inc, Amir Tamiz, Curt W Bradshaw filed Critical Covx Pharmaceuticals Inc
Publication of WO2004091542A2 publication Critical patent/WO2004091542A2/en
Publication of WO2004091542A3 publication Critical patent/WO2004091542A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides integrin targeting compounds which comprise small molecular weight integrin targeting agent-linker conjugates which are linked to a polymer such as a protein. Various uses of the invention compounds are provided, including methods to prevent or treat cancer or other disease.
PCT/US2004/012034 2003-04-15 2004-04-15 Nitrogen containing integrin targeting compounds WO2004091542A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46345603P 2003-04-15 2003-04-15
US60/463,456 2003-04-15
US50788703P 2003-09-30 2003-09-30
US60/507,887 2003-09-30

Publications (2)

Publication Number Publication Date
WO2004091542A2 WO2004091542A2 (en) 2004-10-28
WO2004091542A3 true WO2004091542A3 (en) 2005-04-14

Family

ID=33303121

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/012034 WO2004091542A2 (en) 2003-04-15 2004-04-15 Nitrogen containing integrin targeting compounds

Country Status (1)

Country Link
WO (1) WO2004091542A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080152660A1 (en) * 2005-03-03 2008-06-26 Bradshaw Curt W Anti-Angiogenic Compounds
CA2648522A1 (en) * 2005-04-04 2006-10-12 Daiamed, Inc. Substituted azetidinones
ATE501277T1 (en) 2005-07-01 2011-03-15 Dako Denmark As MONOMERIC AND POLYMERIC LINKERS FOR CONJUGING BIOLOGICAL MOLECULES AND OTHER MATERIALS
WO2008098788A2 (en) * 2007-02-16 2008-08-21 Ktb Tumorforschungsgesellschaft Mbh Receptor and antigen targeted prodrug
ES2435779T3 (en) 2007-07-19 2013-12-23 Sanofi Cytotoxic agents comprising new tomaimycin derivatives and their therapeutic use
US8518927B2 (en) 2009-02-10 2013-08-27 The Scripps Research Institute Chemically programmed vaccination
CN106565825A (en) * 2015-10-12 2017-04-19 复旦大学 Stabilized A7R polypeptide and application of polypeptide in construction of tumor targeted diagnosis and treatment drug delivery system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Also Published As

Publication number Publication date
WO2004091542A2 (en) 2004-10-28

Similar Documents

Publication Publication Date Title
WO2003059251A3 (en) Antibody targeting compounds
WO2006124737A3 (en) Molecular constructs suitable for targeted conjugates
WO2007076371A3 (en) Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same
WO2004093795A3 (en) Compositions for delivery of drug combinations
WO2004108070A3 (en) Releasable polymeric conjugates based on aliphatic biodegradable linkers
WO2002000194A3 (en) Polymeric micelle compositions
WO2004111192A3 (en) Targeted delivery to legumain-expressing cells
WO2006073457A8 (en) Bioactive compounds and methods of uses thereof
WO2005056572A3 (en) Clustered multi-antigenic carbohydrate constructs, methods for their preparation and uses thereof
WO2004084453A3 (en) METHODS OF MANUFACTURE OF 2'-DEOXY-β-L-NUCLEOSIDES
WO2003080582A3 (en) Fredericamycin derivatives
WO2006037024A3 (en) Salts of decitabine
WO2007021937A3 (en) Unsaturated heterocyclic derivatives
WO2004082634A3 (en) Facially amphiphilic polymers and oligomers and uses thereof
WO2005058366A3 (en) Compositions comprising two different populations of polymer-active agent conjugates
WO2006108673A3 (en) Low amounts of high molecular weight polymers for enhancing viscosity of aqueous/aqueous biphasic liquids
WO2003028696A3 (en) Compositions for delivery of drug combinations
WO2008077956A3 (en) Oligonucleotide-, protein and/or peptide-polymer conjugates
WO2009042064A3 (en) Oligomer-nucleoside phosphate conjugates
WO2006097617A3 (en) Novel dihydropyrimidine derivatives and their use as anti-cancer agents
WO2003082268A3 (en) Hemiasterlin derivatives and uses thereof in the treatment of cancer
WO2007059341A3 (en) Pyrazolothiazole protein kinase modulators
WO2005030794A3 (en) Hemiasterlin derivatives and uses thereof
WO2006133006A3 (en) 1-methyl-1h-pyrazole-4-carboxamides useful as cancer chemotherapeutic agents
WO2005000858A3 (en) Bisphosphonate complexes

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 69(1)EPC DATED 26.01.2006.

122 Ep: pct application non-entry in european phase