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WO2003046123A3 - Mutierte gene aus corynebacterium glutamicum - Google Patents

Mutierte gene aus corynebacterium glutamicum Download PDF

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Publication number
WO2003046123A3
WO2003046123A3 PCT/EP2002/012134 EP0212134W WO03046123A3 WO 2003046123 A3 WO2003046123 A3 WO 2003046123A3 EP 0212134 W EP0212134 W EP 0212134W WO 03046123 A3 WO03046123 A3 WO 03046123A3
Authority
WO
WIPO (PCT)
Prior art keywords
corynebacterium glutamicum
mutated gene
organisms
improved micro
genetically improved
Prior art date
Application number
PCT/EP2002/012134
Other languages
English (en)
French (fr)
Other versions
WO2003046123A2 (de
Inventor
Oskar Zelder
Markus Pompejus
Hartwig Schroeder
Burkhard Kroeger
Corinna Klopprogge
Gregor Haberhauer
Original Assignee
Basf Ag
Oskar Zelder
Markus Pompejus
Hartwig Schroeder
Burkhard Kroeger
Corinna Klopprogge
Gregor Haberhauer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Oskar Zelder, Markus Pompejus, Hartwig Schroeder, Burkhard Kroeger, Corinna Klopprogge, Gregor Haberhauer filed Critical Basf Ag
Priority to BR0213779-8A priority Critical patent/BR0213779A/pt
Priority to EP02803765A priority patent/EP1446421A2/de
Priority to AU2002365499A priority patent/AU2002365499A1/en
Priority to KR1020047006758A priority patent/KR100868692B1/ko
Priority to US10/494,672 priority patent/US20050003494A1/en
Publication of WO2003046123A2 publication Critical patent/WO2003046123A2/de
Publication of WO2003046123A3 publication Critical patent/WO2003046123A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Die Erfindung betrifft neue Nukleinsäuremoleküle, deren Verwendung zur Konstruktion von gentechnisch verbesserten Mikroorganismen und Verfahren zur Herstellung von Feinchemikalien, insbesondere Aminosäuren mit Hilfe dieser gentechnisch verbesserten Mikroorganismen.
PCT/EP2002/012134 2001-11-05 2002-10-31 Mutierte gene aus corynebacterium glutamicum WO2003046123A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BR0213779-8A BR0213779A (pt) 2001-11-05 2002-10-31 Molécula de ácido nucleico isolada, vetor, célula hospedeira, e, método para a preparação de um composto de quìmica fina
EP02803765A EP1446421A2 (de) 2001-11-05 2002-10-31 Mutierte gene aus corynebacterium glutamicum
AU2002365499A AU2002365499A1 (en) 2001-11-05 2002-10-31 Mutated gene from corynebacterium glutamicum
KR1020047006758A KR100868692B1 (ko) 2001-11-05 2002-10-31 신규 단백질을 코딩하는 유전자
US10/494,672 US20050003494A1 (en) 2001-11-05 2002-10-31 Mutated gene from corynebacterium glutamicum

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10154177A DE10154177A1 (de) 2001-11-05 2001-11-05 Gene die für neue Proteine codieren
DE10154177.5 2001-11-05

Publications (2)

Publication Number Publication Date
WO2003046123A2 WO2003046123A2 (de) 2003-06-05
WO2003046123A3 true WO2003046123A3 (de) 2004-02-12

Family

ID=7704612

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/012134 WO2003046123A2 (de) 2001-11-05 2002-10-31 Mutierte gene aus corynebacterium glutamicum

Country Status (9)

Country Link
US (1) US20050003494A1 (de)
EP (1) EP1446421A2 (de)
KR (1) KR100868692B1 (de)
CN (1) CN1582300A (de)
AU (1) AU2002365499A1 (de)
BR (1) BR0213779A (de)
DE (1) DE10154177A1 (de)
WO (1) WO2003046123A2 (de)
ZA (1) ZA200404418B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10359661A1 (de) 2003-12-18 2005-07-28 Basf Ag Genvarianten die für Proteine aus dem Stoffwechselweg von Feinchemikalien codieren
BRPI0519410B1 (pt) * 2004-12-28 2020-12-22 Ajinomoto Co., Inc método para produzir ácido l-glutâmico
US7794989B2 (en) 2004-12-28 2010-09-14 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
WO2018009372A1 (en) * 2016-07-05 2018-01-11 Zymergen Inc. Genetic perturbation of the rna degradosome protein complex
CN109929887A (zh) * 2017-12-15 2019-06-25 宁夏伊品生物科技股份有限公司 改进的发酵生产l-赖氨酸的方法
CN109694841A (zh) * 2019-02-02 2019-04-30 江南大学 一种谷氨酸棒状杆菌重组菌、制备方法和应用
CN112877269B (zh) * 2020-01-15 2021-12-24 中国科学院天津工业生物技术研究所 生产赖氨酸的微生物以及赖氨酸的生产方法
CN111979164B (zh) * 2020-08-07 2021-11-12 宁夏伊品生物科技股份有限公司 一种产l-赖氨酸的重组菌株及其构建方法与应用
WO2022027924A1 (zh) * 2020-08-07 2022-02-10 宁夏伊品生物科技股份有限公司 一种产l-氨基酸的重组菌株及其构建方法与应用
KR102281368B1 (ko) * 2021-01-28 2021-07-23 씨제이제일제당 (주) 신규한 단백질 변이체 및 이를 이용한 l-발린 생산 방법
CN115322990B (zh) * 2021-05-10 2024-09-20 中国科学院天津工业生物技术研究所 具有启动子活性的多核苷酸及其在生产目标化合物中的用途
CN113430182B (zh) * 2021-08-09 2023-01-13 云南师范大学 一种来源于亚洲象肠道毛螺菌科的细菌漆酶及其基因
CN115925829B (zh) * 2022-07-22 2024-04-23 东北农业大学 rHtaA-c蛋白在制备用于预防化脓隐秘杆菌的疫苗中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1108790A2 (de) * 1999-12-16 2001-06-20 Kyowa Hakko Kogyo Co., Ltd. Neue Polynukleotide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925427A (en) * 1995-02-06 1999-07-20 Minnesota Mining And Manufacturing Company Support core ribbon for cold-shrink tube

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1108790A2 (de) * 1999-12-16 2001-06-20 Kyowa Hakko Kogyo Co., Ltd. Neue Polynukleotide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EIKMANNS B J ET AL: "MOLECULAR ASPECTS OF LYSINE, THREONINE, AND ISOLEUCINE BIOSYNTHESIS IN CORYNEBACTERIUM GLUTAMICUM", ANTONIE VAN LEEUWENHOEK, DORDRECHT, NL, vol. 64, no. 2, 1993, pages 145 - 163, XP000918559 *

Also Published As

Publication number Publication date
AU2002365499A1 (en) 2003-06-10
WO2003046123A2 (de) 2003-06-05
KR20040053275A (ko) 2004-06-23
DE10154177A1 (de) 2003-05-08
EP1446421A2 (de) 2004-08-18
KR100868692B1 (ko) 2008-11-13
ZA200404418B (en) 2006-07-26
BR0213779A (pt) 2004-10-13
CN1582300A (zh) 2005-02-16
US20050003494A1 (en) 2005-01-06
AU2002365499A8 (en) 2003-06-10

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