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WO2003042371A3 - 55053, a novel human eukaryotic kinase and uses therefor - Google Patents

55053, a novel human eukaryotic kinase and uses therefor Download PDF

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Publication number
WO2003042371A3
WO2003042371A3 PCT/US2002/036967 US0236967W WO03042371A3 WO 2003042371 A3 WO2003042371 A3 WO 2003042371A3 US 0236967 W US0236967 W US 0236967W WO 03042371 A3 WO03042371 A3 WO 03042371A3
Authority
WO
WIPO (PCT)
Prior art keywords
epk
nucleic acid
acid molecules
expression vectors
novel human
Prior art date
Application number
PCT/US2002/036967
Other languages
French (fr)
Other versions
WO2003042371A2 (en
Inventor
Rory A J Curtis
Original Assignee
Millennium Pharm Inc
Rory A J Curtis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/003,690 external-priority patent/US6787345B1/en
Application filed by Millennium Pharm Inc, Rory A J Curtis filed Critical Millennium Pharm Inc
Priority to EP02789727A priority Critical patent/EP1444342A4/en
Priority to AU2002352774A priority patent/AU2002352774A1/en
Publication of WO2003042371A2 publication Critical patent/WO2003042371A2/en
Publication of WO2003042371A3 publication Critical patent/WO2003042371A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated EPK-55053 nucleic acid molecules, which encode novel protein kinase polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing EPK-55053 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an EPK-55053 gene has been introduced or disrupted. The invention still further provides isolated EPK-55053 proteins, fusion proteins, antigenic peptides and anti-EPK-55053 antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
PCT/US2002/036967 2001-11-15 2002-11-15 55053, a novel human eukaryotic kinase and uses therefor WO2003042371A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02789727A EP1444342A4 (en) 2001-11-15 2002-11-15 55053, a novel human eukaryotic kinase and uses therefor
AU2002352774A AU2002352774A1 (en) 2001-11-15 2002-11-15 55053, a novel human eukaryotic kinase and uses therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/003,690 2001-11-15
US10/003,690 US6787345B1 (en) 2000-11-15 2001-11-15 55053, a novel human eukaryotic kinase and uses therefor

Publications (2)

Publication Number Publication Date
WO2003042371A2 WO2003042371A2 (en) 2003-05-22
WO2003042371A3 true WO2003042371A3 (en) 2004-01-22

Family

ID=21707097

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/036967 WO2003042371A2 (en) 2001-11-15 2002-11-15 55053, a novel human eukaryotic kinase and uses therefor

Country Status (3)

Country Link
EP (1) EP1444342A4 (en)
AU (1) AU2002352774A1 (en)
WO (1) WO2003042371A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105566485A (en) * 2015-12-29 2016-05-11 米佳 Anti-tumor polypeptide capable of targeted inhibition of EPK signal channel and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777545B2 (en) * 2001-04-06 2004-08-17 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
EP1240194A2 (en) * 1999-11-24 2002-09-18 Sugen, Inc. Novel human protein kinases and protein kinase-like enzymes
EP1290187A2 (en) * 2000-06-15 2003-03-12 Incyte Genomics, Inc. Humain kinases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE PROTEIN [online] 3 May 1994 (1994-05-03), CHERET ET AL.: "Probable purine nucleotide binding protein YKL101w-yeast (saccharomyces cerevisiae)", XP002965318, Database accession no. (S37928) *
See also references of EP1444342A4 *

Also Published As

Publication number Publication date
AU2002352774A1 (en) 2003-05-26
EP1444342A2 (en) 2004-08-11
WO2003042371A2 (en) 2003-05-22
EP1444342A4 (en) 2005-01-12

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