[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

WO2002034283A3 - Vegh inhibitors and their use - Google Patents

Vegh inhibitors and their use Download PDF

Info

Publication number
WO2002034283A3
WO2002034283A3 PCT/EP2001/012369 EP0112369W WO0234283A3 WO 2002034283 A3 WO2002034283 A3 WO 2002034283A3 EP 0112369 W EP0112369 W EP 0112369W WO 0234283 A3 WO0234283 A3 WO 0234283A3
Authority
WO
WIPO (PCT)
Prior art keywords
inhibitors
vegh
cyclopeptolides
cyclopeptides
factormediated
Prior art date
Application number
PCT/EP2001/012369
Other languages
French (fr)
Other versions
WO2002034283A2 (en
Inventor
Karl Baumann
Carolyn Ann Foster
Philipp Lehr
Josef Gottfried Meingassner
Berndt Oberhauser
Erwin Paul Schreiner
Barbara Wolff-Winiski
Original Assignee
Novartis Ag
Novartis Erfind Verwalt Gmbh
Karl Baumann
Carolyn Ann Foster
Philipp Lehr
Josef Gottfried Meingassner
Berndt Oberhauser
Erwin Paul Schreiner
Barbara Wolff-Winiski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0026345A external-priority patent/GB0026345D0/en
Priority claimed from GB0029113A external-priority patent/GB0029113D0/en
Priority claimed from GB0102379A external-priority patent/GB0102379D0/en
Priority claimed from GB0102380A external-priority patent/GB0102380D0/en
Priority claimed from GB0102839A external-priority patent/GB0102839D0/en
Application filed by Novartis Ag, Novartis Erfind Verwalt Gmbh, Karl Baumann, Carolyn Ann Foster, Philipp Lehr, Josef Gottfried Meingassner, Berndt Oberhauser, Erwin Paul Schreiner, Barbara Wolff-Winiski filed Critical Novartis Ag
Priority to AU2002223649A priority Critical patent/AU2002223649A1/en
Publication of WO2002034283A2 publication Critical patent/WO2002034283A2/en
Publication of WO2002034283A3 publication Critical patent/WO2002034283A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The use of inhibitors of adhesion molecule expression, e.g. cyclopeptolides or cyclopeptides, in the preparation of a medicament for the treatment of vascular endothelial cell growth factormediated diseases and novel cyclopeptolides and cyclopeptides.
PCT/EP2001/012369 2000-10-27 2001-10-25 Vegh inhibitors and their use WO2002034283A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002223649A AU2002223649A1 (en) 2000-10-27 2001-10-25 Vegh inhibitors and their use

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
GB0026345A GB0026345D0 (en) 2000-10-27 2000-10-27 Organic compounds
GB0026345.9 2000-10-27
GB0029113A GB0029113D0 (en) 2000-11-29 2000-11-29 Organic compounds
GB0029113.8 2000-11-29
EP00126150.2 2000-11-30
EP00126150 2000-11-30
GB0102379A GB0102379D0 (en) 2001-01-30 2001-01-30 Organic compounds
GB0102380.3 2001-01-30
GB0102379.5 2001-01-30
GB0102380A GB0102380D0 (en) 2001-01-30 2001-01-30 Organic compounds
GB0102839.8 2001-02-05
GB0102839A GB0102839D0 (en) 2001-02-05 2001-02-05 Organic compounds

Publications (2)

Publication Number Publication Date
WO2002034283A2 WO2002034283A2 (en) 2002-05-02
WO2002034283A3 true WO2002034283A3 (en) 2003-02-13

Family

ID=27545270

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/012369 WO2002034283A2 (en) 2000-10-27 2001-10-25 Vegh inhibitors and their use

Country Status (2)

Country Link
AU (1) AU2002223649A1 (en)
WO (1) WO2002034283A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996003430A1 (en) * 1994-07-27 1996-02-08 Sandoz Ltd. Organic compounds
WO1997019104A1 (en) * 1995-11-21 1997-05-29 Novartis Ag Cyclopeptolides
WO2000038714A1 (en) * 1998-12-30 2000-07-06 Children's Medical Center Corporation The prevention and treatment of retinal ischemia and edema

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996003430A1 (en) * 1994-07-27 1996-02-08 Sandoz Ltd. Organic compounds
WO1997019104A1 (en) * 1995-11-21 1997-05-29 Novartis Ag Cyclopeptolides
WO2000038714A1 (en) * 1998-12-30 2000-07-06 Children's Medical Center Corporation The prevention and treatment of retinal ischemia and edema

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BOGER D L ET AL: "Synthesis and evaluation of Aza HUN-7293", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 10, no. 15, 7 August 2000 (2000-08-07), pages 1741 - 1744, XP004213236, ISSN: 0960-894X *

Also Published As

Publication number Publication date
AU2002223649A1 (en) 2002-05-06
WO2002034283A2 (en) 2002-05-02

Similar Documents

Publication Publication Date Title
WO2004021968A3 (en) Solution for ungual application
AU1200501A (en) Drug delivery catheters that attach to tissue and methods for their use
WO2003087303A3 (en) Tissue composites and uses thereof
EP1214057A4 (en) Vascular coating composition
AU775126C (en) Substituted oxazolidinones and their use in the field of blood coagulation
WO2000044443A3 (en) Intra-pericardial delivery of anti-microtubule agents
AU2002232618A1 (en) Tissue attachable drug delivery catheters/methods of use
CA2436799A1 (en) Combinations of drugs (e.g., chlorpromazine and pentamidine) for the treatment of neoplastic disorders
MXPA03007590A (en) Compositions and methods for enhancing drug delivery across and into ocular tissues.
WO2001068079A3 (en) Viscoelastics for use in middle ear surgery
AU2001247968A1 (en) Use of asiatic acid or asiaticoside for treatment of cancer
HK1047707A1 (en) Use of (+)-tramadol, o-demethyltramadol or (+)-o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol or (+)-o-desmethyl-n-mono-desmethyl-tramadol for treating urinary incontinence
AU2001270484A1 (en) Use of bradycardiac substances in the treatment of myocardial diseases associated with hypertrophy and novel medicament combinations
AU2002230504A1 (en) Ophthalmic irrigating solution adapted for use in lasik surgery
WO2001056627A8 (en) Medical device coated with antimicrobial peptides
AU2002253785A1 (en) Catheter and implants for the delivery of therapeutic agents to tissues
WO2002008222A3 (en) HETEROARYL-β-ALANINE DERIVATIVES AS ALPHA 4 INTEGRIN INHIBITORS
WO2002000208A3 (en) Combination preparations of 3-n-formylhydroxylaminopropyl phosphonic acid derivatives or 3-n-acetylhydroxylaminopropyl phosphonic acid derivatives combined with specific pharmaceutical active agents
WO2002034283A3 (en) Vegh inhibitors and their use
AU6786400A (en) Autologous tissue suture ring used in heart valve implantation
AU7944700A (en) Bio-artificial substrate for the production of animal and, in particular, human tissues and organs
CA2376033A1 (en) Use of l-carnitine and its alkanoyl derivatives for the preparation of a medicament useful for the treatment of patients suffering from diabetic and/or dysmetabolic nephropathy
AU2003242360A1 (en) Culture apparatus, artificial tissue and blood preparation
AU2002356662A1 (en) Tampon, in particular for feminine hygiene or medical purposes
AU2003260566A1 (en) Phenyl-furan or phenyl-thiophene derivatives, their preparation and their use as medicine

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP