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WO2002074330A3 - Mycobacterrial estracts for treating autoimmune diseases - Google Patents

Mycobacterrial estracts for treating autoimmune diseases Download PDF

Info

Publication number
WO2002074330A3
WO2002074330A3 PCT/GB2002/001323 GB0201323W WO02074330A3 WO 2002074330 A3 WO2002074330 A3 WO 2002074330A3 GB 0201323 W GB0201323 W GB 0201323W WO 02074330 A3 WO02074330 A3 WO 02074330A3
Authority
WO
WIPO (PCT)
Prior art keywords
mycobacterrial
estracts
autoimmune diseases
treating autoimmune
treating
Prior art date
Application number
PCT/GB2002/001323
Other languages
French (fr)
Other versions
WO2002074330A2 (en
Inventor
Graham Arthur William Pro Rook
Laura Cristina Rosa Dr Brunet
Original Assignee
Stanford Rook Ltd
Graham Arthur William Pro Rook
Laura Cristina Rosa Dr Brunet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stanford Rook Ltd, Graham Arthur William Pro Rook, Laura Cristina Rosa Dr Brunet filed Critical Stanford Rook Ltd
Priority to AU2002247836A priority Critical patent/AU2002247836A1/en
Publication of WO2002074330A2 publication Critical patent/WO2002074330A2/en
Publication of WO2002074330A3 publication Critical patent/WO2002074330A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention relates to mycobacterial extracts comprising lipids, glycolipids and/or carbohydrates and their use in the treatment of autoimmune disease.
PCT/GB2002/001323 2001-03-20 2002-03-20 Mycobacterrial estracts for treating autoimmune diseases WO2002074330A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002247836A AU2002247836A1 (en) 2001-03-20 2002-03-20 Mycobacterrial estracts for treating autoimmune diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0106985.5 2001-03-20
GBGB0106985.5A GB0106985D0 (en) 2001-03-20 2001-03-20 Immunotherapeutic agent

Publications (2)

Publication Number Publication Date
WO2002074330A2 WO2002074330A2 (en) 2002-09-26
WO2002074330A3 true WO2002074330A3 (en) 2003-10-30

Family

ID=9911181

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/001323 WO2002074330A2 (en) 2001-03-20 2002-03-20 Mycobacterrial estracts for treating autoimmune diseases

Country Status (3)

Country Link
AU (1) AU2002247836A1 (en)
GB (1) GB0106985D0 (en)
WO (1) WO2002074330A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100992646B1 (en) * 2003-07-09 2010-11-05 제이에스알 가부시끼가이샤 Wavelength plate
AU2007323134B2 (en) * 2006-11-23 2013-05-02 Cadila Pharmaceuticals Limited Poly-TLR antagonist
JP2010522155A (en) * 2007-03-20 2010-07-01 カディラ ファーマシューティカルズ リミテッド P38 inhibitor

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716038A (en) * 1984-04-27 1987-12-29 Stanford John L Methods for the alleviation or treatment of arthritic disease
EP0763361A2 (en) * 1992-02-21 1997-03-19 University College London Mycobacterium vaccae for treatment of long term autoimmune conditions
WO1998039025A2 (en) * 1997-03-03 1998-09-11 Adcock Ingram Limited A composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease
WO1998043655A1 (en) * 1997-04-02 1998-10-08 Bioniche Inc. Use of bacterial cell wall extracts for treating topical disorders and wounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716038A (en) * 1984-04-27 1987-12-29 Stanford John L Methods for the alleviation or treatment of arthritic disease
EP0763361A2 (en) * 1992-02-21 1997-03-19 University College London Mycobacterium vaccae for treatment of long term autoimmune conditions
WO1998039025A2 (en) * 1997-03-03 1998-09-11 Adcock Ingram Limited A composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease
WO1998043655A1 (en) * 1997-04-02 1998-10-08 Bioniche Inc. Use of bacterial cell wall extracts for treating topical disorders and wounds

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BARROW WILLIAM W: "Processing of mycobacterial lipids and effects on host responsiveness.", FRONTIERS IN BIOSCIENCE (ONLINE), vol. 2, no. CITED SEPT. 12, 1997, 1997, pages D387 - 400, XP002235435 *
MOURA A C N ET AL: "LIPIDS FROM MYCOBACTERIUM LEPRAE CELL WALL SUPPRESS T-CELL ACTIVATION IN VIVO AND IN VITRO", IMMUNOLOGY, BLACKWELL SCIENTIFIC PUBLICATIONS, GB, vol. 92, no. 4, December 1997 (1997-12-01), pages 429 - 436, XP008014879, ISSN: 0019-2805 *
RABINOVITCH A: "IMMUNOREGULATORY AND CYTOKINE IMBALANCES IN THE PATHOGENESIS OF IDDM THERAPEUTIC INTERVENTION BY IMMUNOSTIMULATION ?", DIABETES, NEW YORK, NY, US, vol. 43, no. 5, May 1994 (1994-05-01), pages 613 - 621, XP001036572, ISSN: 0012-1797 *
RIEDEL D D ET AL: "Differential tolerance induction by lipoarabinomannan and lipopolysaccharide in human macrophages.", MICROBES AND INFECTION / INSTITUT PASTEUR. FRANCE APR 2000, vol. 2, no. 5, April 2000 (2000-04-01), pages 463 - 471, XP002235436, ISSN: 1286-4579 *

Also Published As

Publication number Publication date
GB0106985D0 (en) 2001-05-09
AU2002247836A1 (en) 2002-10-03
WO2002074330A2 (en) 2002-09-26

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