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WO2002072567A3 - Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them - Google Patents

Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them Download PDF

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Publication number
WO2002072567A3
WO2002072567A3 PCT/US2002/007315 US0207315W WO02072567A3 WO 2002072567 A3 WO2002072567 A3 WO 2002072567A3 US 0207315 W US0207315 W US 0207315W WO 02072567 A3 WO02072567 A3 WO 02072567A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
heterocyclic compounds
compound
Prior art date
Application number
PCT/US2002/007315
Other languages
French (fr)
Other versions
WO2002072567A2 (en
Inventor
Duvvuri Subrahmanyam
Sunil Vasantrao Mali
Gopalan Balasubramanian
Aftab Dawoodbhai Lakdawala
Original Assignee
Glenmark Pharmaceuticals Ltd
Mass Clifford J
Duvvuri Subrahmanyam
Sunil Vasantrao Mali
Gopalan Balasubramanian
Aftab Dawoodbhai Lakdawala
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Ltd, Mass Clifford J, Duvvuri Subrahmanyam, Sunil Vasantrao Mali, Gopalan Balasubramanian, Aftab Dawoodbhai Lakdawala filed Critical Glenmark Pharmaceuticals Ltd
Priority to AU2002306687A priority Critical patent/AU2002306687A1/en
Publication of WO2002072567A2 publication Critical patent/WO2002072567A2/en
Publication of WO2002072567A3 publication Critical patent/WO2002072567A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A compound of the general formula (I) and method for preparing and using the compound of formula (I).
PCT/US2002/007315 2001-03-13 2002-03-12 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them WO2002072567A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002306687A AU2002306687A1 (en) 2001-03-13 2002-03-12 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN240/MUM/2001 2001-03-13
IN240MU2001 2001-03-13

Publications (2)

Publication Number Publication Date
WO2002072567A2 WO2002072567A2 (en) 2002-09-19
WO2002072567A3 true WO2002072567A3 (en) 2002-11-28

Family

ID=11097228

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/007315 WO2002072567A2 (en) 2001-03-13 2002-03-12 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them

Country Status (2)

Country Link
AU (1) AU2002306687A1 (en)
WO (1) WO2002072567A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0314721A (en) * 2002-10-23 2005-08-02 Glenmark Pharmaceuticals Ltd Tricyclic compounds useful for treating inflammatory and allergic disorders, processes for their preparation and pharmaceutical compositions containing them
WO2004069831A1 (en) * 2003-02-10 2004-08-19 Glenmark Pharmaceuticals Ltd. Tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation
EP1620429B1 (en) 2003-04-11 2009-04-01 Glenmark Pharmaceuticals S.A. Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
WO2004111044A1 (en) * 2003-06-17 2004-12-23 Glenmark Pharmaceuticals Ltd. Tricyclic compounds useful for the treatment of inflammatory and allergic disorders:process for their preparation
CA2583497A1 (en) 2004-10-13 2006-04-20 Glenmark Pharmaceuticals S.A. Process for the preparation of n-(3,5-dichloropyrid-4-yl)-4difluoromethoxy-8-methanesulfonamido-dibenzo[b,d]furan-1-carboxamide
WO2006064355A2 (en) 2004-12-17 2006-06-22 Glenmark Pharmaceuticals S.A. Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders
CN101124229B (en) 2004-12-17 2012-07-18 格兰马克药品股份有限公司 Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders
TW201711999A (en) 2015-09-03 2017-04-01 佛瑪治療公司 [6,6] fused bicyclic HDAC8 inhibitors
GB201801130D0 (en) 2018-01-24 2018-03-07 Univ Oxford Innovation Ltd Compounds

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1193637A (en) * 1957-01-08 1959-11-04 Rhone Poulenc Sa New acyl and amine derivatives of benzodioxane
US3157674A (en) * 1963-04-30 1964-11-17 Ciba Geigy Corp 2-(cycloaliphatic-alkyl-aminomethyl)-benzodioxanes
DE1518042A1 (en) * 1965-11-11 1969-06-12 Merck Ag E Process for the preparation of 1,4-benzodioxane derivatives
DE2840454A1 (en) * 1978-09-16 1980-04-03 Madaus & Co Dr 3,4-Di:hydroxy-cinnamaldehyde dimer - is anti-hepato:toxic agent obtd. by treating the acetone isolation prod. of Phytolacca fruits with alkali
GB2046259A (en) * 1979-03-20 1980-11-12 Kyowa Hakko Kogyo Kk Amino-alcohol derivatives and pharmaceutical compositions containing them
WO1992018494A1 (en) * 1991-04-19 1992-10-29 Ciba-Geigy Ag Methyl esters of aldimino- or ketimino-oxy-orthotolylacrylic acid, manufacturing process and fungicides containing them

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1193637A (en) * 1957-01-08 1959-11-04 Rhone Poulenc Sa New acyl and amine derivatives of benzodioxane
US3157674A (en) * 1963-04-30 1964-11-17 Ciba Geigy Corp 2-(cycloaliphatic-alkyl-aminomethyl)-benzodioxanes
DE1518042A1 (en) * 1965-11-11 1969-06-12 Merck Ag E Process for the preparation of 1,4-benzodioxane derivatives
DE2840454A1 (en) * 1978-09-16 1980-04-03 Madaus & Co Dr 3,4-Di:hydroxy-cinnamaldehyde dimer - is anti-hepato:toxic agent obtd. by treating the acetone isolation prod. of Phytolacca fruits with alkali
GB2046259A (en) * 1979-03-20 1980-11-12 Kyowa Hakko Kogyo Kk Amino-alcohol derivatives and pharmaceutical compositions containing them
WO1992018494A1 (en) * 1991-04-19 1992-10-29 Ciba-Geigy Ag Methyl esters of aldimino- or ketimino-oxy-orthotolylacrylic acid, manufacturing process and fungicides containing them

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALEJANDRA G. SUAREZ: "ALCL3-DMA REAGENT", TETRAHEDRON LETTERS., vol. 40, 1999, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM., NL, pages 3523 - 6, XP004162326, ISSN: 0040-4039 *
V. THIÉRY ET AL.: "CONVENIENT SYNTHESIS OF 2-SUBST. 6- OR 7-ACYLATED 1,4-BENZODIOXIN", TETRAHEDRON., vol. 51, no. 9, 1995, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM., NL, pages 2619 - 28, XP002214666, ISSN: 0040-4020 *

Also Published As

Publication number Publication date
WO2002072567A2 (en) 2002-09-19
AU2002306687A1 (en) 2002-09-24

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