[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

WO2000034477A3 - Neuron-associated proteins - Google Patents

Neuron-associated proteins Download PDF

Info

Publication number
WO2000034477A3
WO2000034477A3 PCT/US1999/030408 US9930408W WO0034477A3 WO 2000034477 A3 WO2000034477 A3 WO 2000034477A3 US 9930408 W US9930408 W US 9930408W WO 0034477 A3 WO0034477 A3 WO 0034477A3
Authority
WO
WIPO (PCT)
Prior art keywords
neuap
associated proteins
neuron
provides
expression
Prior art date
Application number
PCT/US1999/030408
Other languages
French (fr)
Other versions
WO2000034477A2 (en
Inventor
Y Tom Tang
Henry Yue
Mariah R Baughn
Jennifer L Hillman
Preeti Lal
Janice Au-Young
Junming Yang
Dyung Aina M Lu
Yalda Azimzai
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Henry Yue
Mariah R Baughn
Jennifer L Hillman
Preeti Lal
Au Young Janice
Junming Yang
Dyung Aina M Lu
Yalda Azimzai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Henry Yue, Mariah R Baughn, Jennifer L Hillman, Preeti Lal, Au Young Janice, Junming Yang, Dyung Aina M Lu, Yalda Azimzai filed Critical Incyte Pharma Inc
Priority to EP99967468A priority Critical patent/EP1135494A2/en
Priority to JP2000586911A priority patent/JP2003518913A/en
Priority to AU23738/00A priority patent/AU2373800A/en
Priority to CA002353797A priority patent/CA2353797A1/en
Publication of WO2000034477A2 publication Critical patent/WO2000034477A2/en
Publication of WO2000034477A3 publication Critical patent/WO2000034477A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides human neuron-associated proteins (NEUAP) and polynucleotides which identify and encode NEUAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of NEUAP.
PCT/US1999/030408 1998-12-11 1999-12-10 Neuron-associated proteins WO2000034477A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99967468A EP1135494A2 (en) 1998-12-11 1999-12-10 Neuron-associated proteins
JP2000586911A JP2003518913A (en) 1998-12-11 1999-12-10 Neuron-related proteins
AU23738/00A AU2373800A (en) 1998-12-11 1999-12-10 Neuron-associated proteins
CA002353797A CA2353797A1 (en) 1998-12-11 1999-12-10 Neuron-associated proteins

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US21008398A 1998-12-11 1998-12-11
US09/210,083 1998-12-11
US11936599P 1999-02-09 1999-02-09
US60/119,365 1999-02-09
US12468799P 1999-03-16 1999-03-16
US60/124,687 1999-03-16

Publications (2)

Publication Number Publication Date
WO2000034477A2 WO2000034477A2 (en) 2000-06-15
WO2000034477A3 true WO2000034477A3 (en) 2000-11-09

Family

ID=27382298

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/030408 WO2000034477A2 (en) 1998-12-11 1999-12-10 Neuron-associated proteins

Country Status (5)

Country Link
EP (1) EP1135494A2 (en)
JP (1) JP2003518913A (en)
AU (1) AU2373800A (en)
CA (1) CA2353797A1 (en)
WO (1) WO2000034477A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2050762A3 (en) * 1998-03-10 2009-07-08 Genentech, Inc. Human cornichon-like protein and nucleic acids encoding it
US7723488B2 (en) 1998-03-27 2010-05-25 Genentech, Inc. Monoclonal antibodies to secreted and transmembrane polypeptides
PT1632499E (en) * 1999-03-08 2007-09-11 Genentech Inc Gene sequences amplified in tumours and their diagnostic uses
US7129324B2 (en) * 1999-06-22 2006-10-31 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20090176722A9 (en) 2000-01-28 2009-07-09 Shiv Srivastava Androgen-regulated PMEPA1 gene and polypeptides
WO2002016416A2 (en) * 2000-08-22 2002-02-28 The Brigham And Women's Hospital, Inc. Diagnosis and treatment of cardiovascular conditions
US20030207801A1 (en) * 2000-10-23 2003-11-06 Valerie Gerlach Novel polypeptides and nucleic acids encoding same
ES2278916T3 (en) * 2001-05-25 2007-08-16 Nymox Corporation PEPTIDES OBTAINED FROM NEURAL CHAIN PROTEINS AND THEIR MEDICAL USE.
EP1847550A3 (en) * 2001-07-19 2008-01-09 Nymox Corporation Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
US7192929B2 (en) * 2001-07-19 2007-03-20 Nymox Corporation Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
US7317077B2 (en) 2001-11-16 2008-01-08 Nymox Pharmaceutical Corporation Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
WO2005014818A1 (en) 2003-08-08 2005-02-17 Perseus Proteomics Inc. Gene overexpressed in cancer
RU2365382C2 (en) 2004-04-14 2009-08-27 Дженентек, Инк. Compositions and methods for regulation of vessels development
WO2007130627A2 (en) 2006-05-04 2007-11-15 The Brigham And Women's Hospital, Inc. Il-33 in the treatment and diagnosis of diseases and disorders
AR076662A1 (en) 2009-05-08 2011-06-29 Genentech Inc ANTI-EGFL7 HUMANIZED ANTIBODIES AND METHODS OF THE SAME USE
US11628202B2 (en) 2015-07-24 2023-04-18 Nymox Corporation Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia
US10183058B2 (en) 2016-06-17 2019-01-22 Nymox Corporation Method of preventing or reducing the progression of prostate cancer
US10172910B2 (en) 2016-07-28 2019-01-08 Nymox Corporation Method of preventing or reducing the incidence of acute urinary retention
US10532081B2 (en) 2016-09-07 2020-01-14 Nymox Corporation Method of ameliorating or preventing the worsening or the progression of symptoms of BPH
US10335453B2 (en) 2017-03-01 2019-07-02 Nymox Corporation Compositions and methods for improving sexual function
WO2022011284A1 (en) * 2020-07-10 2022-01-13 Ohio State Innovation Foundation Epidermal growth factor-like 7 peptide and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006554A2 (en) * 1997-08-01 1999-02-11 Genset 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN MUSCLE AND OTHER MESODERMAL TISSUES

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006554A2 (en) * 1997-08-01 1999-02-11 Genset 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN MUSCLE AND OTHER MESODERMAL TISSUES

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, BUCKEL ALEX ET AL: "Cloning of cDNA encoding human rapsyn and mapping of the RAPSN gene locus to chromosome 11p11.2-p11.1.", XP002136769, Database accession no. PREV199699135023 *
GENOMICS 1996, vol. 35, no. 3, 1996, pages 613 - 616, ISSN: 0888-7543 *
NATIONAL CANCER INSTITUTE, CANCER GENOME ANATOMY PROJECT (CGAP): "Homo sapiens cDNA clone", EMEST DATABASE ENTRY AI022447, ACCESSION NUMBER AI022447, 19 June 1998 (1998-06-19), XP002136735 *

Also Published As

Publication number Publication date
EP1135494A2 (en) 2001-09-26
WO2000034477A2 (en) 2000-06-15
AU2373800A (en) 2000-06-26
JP2003518913A (en) 2003-06-17
CA2353797A1 (en) 2000-06-15

Similar Documents

Publication Publication Date Title
WO1999061471A3 (en) Human transmembrane proteins
WO2001012662A3 (en) Membrane associated proteins
WO2000015793A3 (en) Human gpcr proteins
WO2000034477A3 (en) Neuron-associated proteins
WO2000018922A3 (en) Human carbohydrate-associated proteins
WO1999058692A3 (en) Human apoptosis associated proteins
WO2000009709A3 (en) Proteases and associated proteins
WO2000012711A3 (en) Human membrane channel proteins
WO2000029583A3 (en) Immunoglobulin superfamily proteins
WO2000012703A3 (en) Protein transport-associated molecules
WO2000017355A3 (en) Human cytoskeleton associated proteins
WO2001020004A3 (en) Protein phosphatase and kinase proteins
WO2000014251A3 (en) Human transferase proteins
WO2000052151A3 (en) Human secretory proteins
WO1999058558A3 (en) Cell signaling proteins
WO2000000594A3 (en) Human transferases
WO1999061614A3 (en) Human socs proteins
WO2000031263A3 (en) Gtpase associated proteins
WO2000028045A3 (en) Human hydrolase proteins
WO2000023589A3 (en) Proliferation and apoptosis related proteins
WO2000065054A3 (en) Human membrane-associated proteins
WO2000008155A3 (en) Human receptor-associated proteins
WO1999049037A3 (en) Protein phosphatase-related molecules
WO2000001821A3 (en) Neurotransmission associated proteins
WO2000060082A3 (en) Vesicle associated proteins

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US US US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US US US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

ENP Entry into the national phase

Ref document number: 2353797

Country of ref document: CA

Ref country code: CA

Ref document number: 2353797

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 09857826

Country of ref document: US

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 586911

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1999967468

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1999967468

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 1999967468

Country of ref document: EP