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WO2000034473A3 - Seven transmembrane domain receptor zsig56 - Google Patents

Seven transmembrane domain receptor zsig56 Download PDF

Info

Publication number
WO2000034473A3
WO2000034473A3 PCT/US1999/028492 US9928492W WO0034473A3 WO 2000034473 A3 WO2000034473 A3 WO 2000034473A3 US 9928492 W US9928492 W US 9928492W WO 0034473 A3 WO0034473 A3 WO 0034473A3
Authority
WO
WIPO (PCT)
Prior art keywords
zsig56
transmembrane domain
domain receptor
polypeptides
present
Prior art date
Application number
PCT/US1999/028492
Other languages
French (fr)
Other versions
WO2000034473A2 (en
Inventor
Paul O Sheppard
Jeff L Ellsworth
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU21620/00A priority Critical patent/AU2162000A/en
Publication of WO2000034473A2 publication Critical patent/WO2000034473A2/en
Publication of WO2000034473A3 publication Critical patent/WO2000034473A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to polynucleotide and polypeptide molecules for a seven transmembrane domain receptor designated zsig56. The polypeptides, and polynucleotides encoding them are useful treating pathological conditions in such diverse tissue, as kidney, thyroid, gastrointestinal, CSN and reproductive. Such conditions include hypertension, hyper- and hypothyroidism, neurotransmission, gastrointestinal motility, inflammation and reproduction. The present invention also includes antibodies to the zsig56 polypeptides.
PCT/US1999/028492 1998-12-10 1999-12-02 Seven transmembrane domain receptor zsig56 WO2000034473A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU21620/00A AU2162000A (en) 1998-12-10 1999-12-02 Seven transmembrane domain receptor zsig56

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20869198A 1998-12-10 1998-12-10
US09/208,691 1998-12-10

Publications (2)

Publication Number Publication Date
WO2000034473A2 WO2000034473A2 (en) 2000-06-15
WO2000034473A3 true WO2000034473A3 (en) 2000-08-17

Family

ID=22775610

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/028492 WO2000034473A2 (en) 1998-12-10 1999-12-02 Seven transmembrane domain receptor zsig56

Country Status (2)

Country Link
AU (1) AU2162000A (en)
WO (1) WO2000034473A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2367822A (en) * 2000-06-19 2002-04-17 Smithkline Beecham Corp CD97 polypeptides
US20040048284A1 (en) * 2000-12-07 2004-03-11 Shuji Sato Novel g protein-coupled receptor protein and dna thereof
US20030096345A1 (en) * 2001-01-22 2003-05-22 Millennium Pharmaceuticals, Inc. 15569, a novel human G protein coupled receptor and uses therefor
WO2002061083A1 (en) * 2001-01-30 2002-08-08 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof
EP1554310A1 (en) * 2002-10-22 2005-07-20 Schering Aktiengesellschaft Epididymis-specific gene as potential contraceptive target
JP4898120B2 (en) 2002-12-20 2012-03-14 アボット バイオセラピューティクス コーポレイション Antibodies against GPR64 and methods of use thereof
WO2005040826A2 (en) * 2003-10-24 2005-05-06 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 64 (gpr64)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015551A1 (en) * 1997-09-24 1999-04-01 Garvan Institute Of Medical Research Novel receptor
WO1999018126A1 (en) * 1997-10-07 1999-04-15 Ono Pharmaceutical Co., Ltd. POLYPEPTIDE, cDNA ENCODING THE POLYPEPTIDE, AND USE OF THE BOTH
WO1999046281A2 (en) * 1998-03-10 1999-09-16 Genentech, Inc. Novel polypeptides and nucleic acids encoding the same
WO2000020590A2 (en) * 1998-10-06 2000-04-13 Incyte Pharmaceuticals, Inc. G-protein coupled receptor proteins

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015551A1 (en) * 1997-09-24 1999-04-01 Garvan Institute Of Medical Research Novel receptor
WO1999018126A1 (en) * 1997-10-07 1999-04-15 Ono Pharmaceutical Co., Ltd. POLYPEPTIDE, cDNA ENCODING THE POLYPEPTIDE, AND USE OF THE BOTH
WO1999046281A2 (en) * 1998-03-10 1999-09-16 Genentech, Inc. Novel polypeptides and nucleic acids encoding the same
WO2000020590A2 (en) * 1998-10-06 2000-04-13 Incyte Pharmaceuticals, Inc. G-protein coupled receptor proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LIU M. ET AL.: "GPR56, a novel secretin-like human G-protein-coupled receptor gene.", GENOMICS, vol. 55, no. 3, 1 February 1999 (1999-02-01), pages 296 - 305, XP002137722, ISSN: 0888-7543 *
ZENDMAN A. J. ET AL.: "TM7XN1, a novel EGF-TM7-like cDNA, detected with mRA differential display using human melanoma cell lines with different metastatic potential", FEBS LETTERS, vol. 446, no. 2/03, 12 March 1999 (1999-03-12), pages 292 - 298-298, XP002110422, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
AU2162000A (en) 2000-06-26
WO2000034473A2 (en) 2000-06-15

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