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WO2000008169A8 - Sequence adn codant pour une 1-deoxy-d-xylulose-5-phosphate synthase et sa surproduction dans les plantes - Google Patents

Sequence adn codant pour une 1-deoxy-d-xylulose-5-phosphate synthase et sa surproduction dans les plantes

Info

Publication number
WO2000008169A8
WO2000008169A8 PCT/EP1999/005467 EP9905467W WO0008169A8 WO 2000008169 A8 WO2000008169 A8 WO 2000008169A8 EP 9905467 W EP9905467 W EP 9905467W WO 0008169 A8 WO0008169 A8 WO 0008169A8
Authority
WO
WIPO (PCT)
Prior art keywords
xylulose
overproduction
deoxy
plants
phosphate synthase
Prior art date
Application number
PCT/EP1999/005467
Other languages
German (de)
English (en)
Other versions
WO2000008169A1 (fr
Inventor
Andreas Reindl
Mejia Patricia Leon
Palmas Juan Manuel Esteves
Gracia Maria Araceli Cantero
Marcus Ebneth
Karin Herbers
Original Assignee
Sungene Gmbh & Co Kgaa
Andreas Reindl
Mejia Patricia Leon
Palmas Juan Manuel Esteves
Gracia Maria Araceli Cantero
Marcus Ebneth
Karin Herbers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1998135219 external-priority patent/DE19835219A1/de
Priority claimed from DE1998145224 external-priority patent/DE19845224A1/de
Priority claimed from DE1998145216 external-priority patent/DE19845216A1/de
Priority claimed from DE1998145231 external-priority patent/DE19845231A1/de
Application filed by Sungene Gmbh & Co Kgaa, Andreas Reindl, Mejia Patricia Leon, Palmas Juan Manuel Esteves, Gracia Maria Araceli Cantero, Marcus Ebneth, Karin Herbers filed Critical Sungene Gmbh & Co Kgaa
Priority to CA002339519A priority Critical patent/CA2339519A1/fr
Priority to EP99940083A priority patent/EP1102852A1/fr
Priority to AU54157/99A priority patent/AU757440B2/en
Priority to JP2000563793A priority patent/JP2002525034A/ja
Publication of WO2000008169A1 publication Critical patent/WO2000008169A1/fr
Publication of WO2000008169A8 publication Critical patent/WO2000008169A8/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0069Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1022Transferases (2.) transferring aldehyde or ketonic groups (2.2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Procédé d'obtention de plantes à capacité de biosynthèse de vitamine E accrue, par surexpression d'un gène végétal de 1-déoxy-D-xylulose-5-phosphate synthase d'Arabidopsis ou de E. coli.
PCT/EP1999/005467 1998-08-05 1999-07-30 Sequence adn codant pour une 1-deoxy-d-xylulose-5-phosphate synthase et sa surproduction dans les plantes WO2000008169A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002339519A CA2339519A1 (fr) 1998-08-05 1999-07-30 Sequence adn codant pour une 1-deoxy-d-xylulose-5-phosphate synthase et sa surproduction dans les plantes
EP99940083A EP1102852A1 (fr) 1998-08-05 1999-07-30 Sequence adn codant pour une 1-deoxy-d-xylulose-5-phosphate synthase et sa surproduction dans les plantes
AU54157/99A AU757440B2 (en) 1998-08-05 1999-07-30 DNA sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants
JP2000563793A JP2002525034A (ja) 1998-08-05 1999-07-30 1−デオキシ−d−キシルロース−5−リン酸シンターゼをコードするdna配列および植物におけるその過剰産生

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE19835219.0 1998-08-05
DE1998135219 DE19835219A1 (de) 1998-08-05 1998-08-05 DNA-Sequenz codierend für eine 1-Deoxy-D-Xylulose-5-Phosphat Synthase und deren Überproduktion in Pflanzen
DE19845224.1 1998-10-01
DE1998145224 DE19845224A1 (de) 1998-10-01 1998-10-01 DNA-Sequenzen codierend für eine 1-Deoxy-D-Xylulose-5-Phosphat Synthase und eine Geranylgeranyl-Pyrosphat Oxidoreduktase und deren Überproduktion in Pflanzen
DE1998145216 DE19845216A1 (de) 1998-10-01 1998-10-01 DNA-Sequenzen codierend für eine 1-Deoxy-D-Xylulose-5-Phosphat Synthase und eine Hydroxyphenylpyruvat Dioxygenase und deren Überproduktion in Pflanzen
DE19845216.0 1998-10-01
DE1998145231 DE19845231A1 (de) 1998-10-01 1998-10-01 DNA-Sequenzen codierend für eine 1-Deoxy-D-Xylulose-5-Pphosphat Synthase, eine Hydroxyphenylpyruvat Dioxygenase und eine Geranylgeranylpyrophosphat Oxidoreduktase und deren Überproduktion in Pflanzen
DE19845231.4 1998-10-01

Publications (2)

Publication Number Publication Date
WO2000008169A1 WO2000008169A1 (fr) 2000-02-17
WO2000008169A8 true WO2000008169A8 (fr) 2000-05-04

Family

ID=27438844

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/005467 WO2000008169A1 (fr) 1998-08-05 1999-07-30 Sequence adn codant pour une 1-deoxy-d-xylulose-5-phosphate synthase et sa surproduction dans les plantes

Country Status (5)

Country Link
EP (1) EP1102852A1 (fr)
JP (1) JP2002525034A (fr)
AU (1) AU757440B2 (fr)
CA (1) CA2339519A1 (fr)
WO (1) WO2000008169A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2175025A1 (fr) 1998-04-14 2010-04-14 Kyowa Hakko Bio Co., Ltd. Procédé de production de composés isoprénoides au moyen de micro-organismes
GB9901902D0 (en) * 1999-01-28 1999-03-17 New Royal Holloway & Bedford Manipulating isoprenoid expression
DE19903493A1 (de) * 1999-01-29 2000-08-03 Basf Ag Überexpression einer DNA-Sequenz codierend für eine Transketolase in Pflanzen
ATE358723T1 (de) 1999-04-15 2007-04-15 Calgene Llc Nukleinsäuresequenzen für proteine die an der isoprenoid-synthese beteiligt sind
DE19937957A1 (de) * 1999-08-11 2001-02-15 Sungene Gmbh & Co Kgaa Homogentisat-Dioxygenase
US20020072503A1 (en) * 2000-03-28 2002-06-13 Jiangchun Xu Compositions and methods for the therapy and diagnosis of ovarian cancer
US6632630B2 (en) 2000-03-29 2003-10-14 Aclara Biosciences, Inc. Monooxygenase assays
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
AR030430A1 (es) 2000-06-29 2003-08-20 Sungene Gmbh & Co Kgaa Procedimiento para la obtencion de quimicos finos por cultivo de organismos que presentan una via de shiquimato modificada, composicion de acido nucleinico, uso de dicho acido nucleinico para la obtencion de plantas transgenicas, organismo geneticamente modificado, procedimiento para la produccion d
US6326164B1 (en) * 2000-07-27 2001-12-04 Paradigm Genetics, Inc. Methods for determining deoxyxylulose 5-phosphate synthase activity
WO2002012478A2 (fr) 2000-08-07 2002-02-14 Monsanto Technology, Llc Genes de la voie methyl-d-erythritol phosphate
DE10111676A1 (de) 2001-03-09 2002-09-12 Sungene Gmbh & Co Kgaa Erhöhung des Vitamin-E-Gehalts in Organismen durch Erhöhung der Tyrosinaminotransferase-Aktivität
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
JP2004533244A (ja) 2001-05-09 2004-11-04 モンサント テクノロジー リミテッド ライアビリティー カンパニー TyrA遺伝子及びその使用法
WO2003016482A2 (fr) 2001-08-17 2003-02-27 Monsanto Technology Llc Genes de methyltransferase et leurs utilisations
BR0213499A (pt) 2001-10-25 2004-11-03 Monsanto Technology Llc Metiltransferases aromáticas e seu uso
CA2478957C (fr) 2002-03-19 2013-07-02 Monsanto Technology, Llc Acides nucleiques et polypeptides se rapportant a l'enzyme homogentisate prenyl transferase ("hpt"), et utilisations correspondantes
WO2004013312A2 (fr) 2002-08-05 2004-02-12 Monsanto Technology, Llc Genes associes a la biosynthese du tocopherol et utilisation de ceux-ci
FR2844142B1 (fr) 2002-09-11 2007-08-17 Bayer Cropscience Sa Plantes transformees a biosynthese de prenylquinones amelioree
DE10260871A1 (de) * 2002-12-23 2004-07-08 Sungene Gmbh & Co. Kgaa Verfahren zur Herstellung von transgenen Pflanzen mit erhöhtem Vitamin E-Gehalt durch Veränderung des Serin-Acetyltransferase-Gehalts
JP2007244240A (ja) * 2006-03-14 2007-09-27 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai 緑色カルス細胞の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19501906A1 (de) * 1995-01-23 1996-07-25 Basf Ag Transketolase
US6087563A (en) * 1996-01-29 2000-07-11 Arizona Board Of Regents On Behalf Of The University Of Arizona Cloned arabidopsis p-hydroxyphenyl pyruvic acid dioxygenase DNA
CA2261577A1 (fr) * 1996-08-09 1998-02-19 Calgene, Inc. Procedes de fabrication de composes carotenoides et d'huiles speciales a partir de graines de plantes
US6190895B1 (en) * 1997-09-02 2001-02-20 Washington State University Research Foundation Nucleic and amino acid sequences relating to a novel transketolase, and methods for the expression thereof
DE19752700A1 (de) * 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Desoxy-D-xylulose-5-phosphat Synthase, Verfahren zur Identifizierung von Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase und Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase
SK15232000A3 (sk) * 1998-04-14 2001-05-10 Hassan Jomaa Spôsob identifikácie chemických účinných látok a prostriedkov inhibície biosyntetickej cesty 1-deoxy-d-xylulóza-5-fosfátu

Also Published As

Publication number Publication date
CA2339519A1 (fr) 2000-02-17
JP2002525034A (ja) 2002-08-13
AU5415799A (en) 2000-02-28
EP1102852A1 (fr) 2001-05-30
AU757440B2 (en) 2003-02-20
WO2000008169A1 (fr) 2000-02-17

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