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WO2000045804A3 - Prevention de la formation d'abces - Google Patents

Prevention de la formation d'abces Download PDF

Info

Publication number
WO2000045804A3
WO2000045804A3 PCT/US2000/002988 US0002988W WO0045804A3 WO 2000045804 A3 WO2000045804 A3 WO 2000045804A3 US 0002988 W US0002988 W US 0002988W WO 0045804 A3 WO0045804 A3 WO 0045804A3
Authority
WO
WIPO (PCT)
Prior art keywords
prevention
abscess formation
polyanionic polysaccharide
polysaccharide solution
solution
Prior art date
Application number
PCT/US2000/002988
Other languages
English (en)
Other versions
WO2000045804A2 (fr
Inventor
James W Burns
Eugene Skrabut
Goor Harry Van
Michel M P J Reijnen
Original Assignee
Genzyme Corp
Univ Hospital Nijmegen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Univ Hospital Nijmegen filed Critical Genzyme Corp
Priority to AU33566/00A priority Critical patent/AU3356600A/en
Priority to CA002361572A priority patent/CA2361572A1/fr
Priority to EP00911708A priority patent/EP1148886A2/fr
Priority to JP2000596924A priority patent/JP2002536323A/ja
Publication of WO2000045804A2 publication Critical patent/WO2000045804A2/fr
Publication of WO2000045804A3 publication Critical patent/WO2000045804A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

L'invention concerne un procédé relatif à la prévention ou à la réduction de la gravité de la formation d'un abcès chez l'homme, qui consiste à utiliser une solution diluée de polysaccharide polyanionique, et de préférence une solution d'acide hyaluronique ou de carboxyméthylcellulose, en application au tissu sur le site d'une procédure chirurgicale.
PCT/US2000/002988 1999-02-04 2000-02-04 Prevention de la formation d'abces WO2000045804A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU33566/00A AU3356600A (en) 1999-02-04 2000-02-04 Prevention of abscess formation
CA002361572A CA2361572A1 (fr) 1999-02-04 2000-02-04 Prevention de la formation d'abces
EP00911708A EP1148886A2 (fr) 1999-02-04 2000-02-04 Prevention de la formation d'abces
JP2000596924A JP2002536323A (ja) 1999-02-04 2000-02-04 膿瘍形成の予防

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11870799P 1999-02-04 1999-02-04
US60/118,707 1999-02-04

Publications (2)

Publication Number Publication Date
WO2000045804A2 WO2000045804A2 (fr) 2000-08-10
WO2000045804A3 true WO2000045804A3 (fr) 2001-03-08

Family

ID=22380260

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/002988 WO2000045804A2 (fr) 1999-02-04 2000-02-04 Prevention de la formation d'abces

Country Status (5)

Country Link
EP (1) EP1148886A2 (fr)
JP (1) JP2002536323A (fr)
AU (1) AU3356600A (fr)
CA (1) CA2361572A1 (fr)
WO (1) WO2000045804A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002154906A (ja) 2000-11-13 2002-05-28 Michio Hayashi 抗菌剤組成物
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7238677B2 (en) 2003-03-28 2007-07-03 Kimberly-Clark Worldwide, Inc. Prevention of urogenital infections
JP5039552B2 (ja) * 2005-08-04 2012-10-03 帝人株式会社 セルロース誘導体
RU2486892C1 (ru) * 2011-11-25 2013-07-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального обучения "Хакасский государственный университет им. Н.Ф. Катанова" (ФГБОУ ВПО "ХГУ им. Н.Ф.Катанова") Способ лимфотропной терапии при ортодентальных абсцессах у кроликов

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004058A2 (fr) * 1989-09-21 1991-04-04 Norpharmco Inc. Traitement de maladies et d'etats pathologiques
JPH09208476A (ja) * 1996-01-26 1997-08-12 Takada Seiyaku Kk 腹腔内投与用医薬組成物
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004058A2 (fr) * 1989-09-21 1991-04-04 Norpharmco Inc. Traitement de maladies et d'etats pathologiques
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
JPH09208476A (ja) * 1996-01-26 1997-08-12 Takada Seiyaku Kk 腹腔内投与用医薬組成物

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
BURNS, J.W. ET AL: "Prevention of tissue injury and postsurgical adhesions by precoating tissues with hyaluronic acid solutions", JOURNAL OF SURGICAL RESEARCH, vol. 59, no. 6, - 1995, pages 644 - 652, XP000952895 *
DATABASE EMBASE ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; XP002151239 *
FOSCHI, D. ET AL: "Hyaluronic acid prevents oxygen free-radical damage to granulation tissue: a study in rats", INTERNATIONAL JOURNAL OF TISSUE REACTIONS, vol. 12, no. 6, 1990, pages 333 - 339, XP000953074 *
MUELLER, P.O.E. ET AL: "Intraperitoneal use of sodium carboxymethylcellulose in horses undergoing exploratory celiotomy", VETERINARY SURGERY, vol. 24, no. 2, 1995, pages 112 - 117, XP000953146 *
NARAMA, I. ET AL: "26-week chronic toxicity study and 5-week recovery test of high molecular weight sodium hyaluronate (NRD101) in rats by intraperitoneal administration", JAPANESE PHARMACOLOGY AND THERAPEUTICS, vol. 22, no. SUPPL. 3, 1994, pages 93 - 134 *
ONDERDONK, A.B. ET AL: "Immunomodulatory effects of derivatized hyaluronic acid-carboxymethylcellulose gels (DHA) in an animal model for intraabdominal sepsis", ABSTRACTS OF THE 99TH GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 99, 1 June 1999 (1999-06-01), pages 11, XP000953083 *
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 12 (C - ) 25 December 1997 (1997-12-25) *
PECK, L.S. ET AL: "Evaluation of CMC and HA solutions for adhesiolysis", JOURNAL OF INVESTIGATIVE SURGERY, vol. 8, 1995, pages 337 - 348, XP000953093 *
REIJNEN, M.M. ET AL: "Prevention of intraabdominal abscesses and adhesions using a hyaluronic acid solution in a rat peritonitis model", ARCHIVES OF SURGERY, vol. 134, no. 9, September 1999 (1999-09-01), pages 997 - 1001, XP000952881 *
TZIANABOS, A.O. ET AL: "Structure and function of Bacteroides fragilis capsular polysaccharides: Relationship to induction and prevention of abscesses", CLINICL INFECTIOUS DISEASES, vol. 20, no. suppl. 2, 1995, pages S132 - S140, XP000952888 *
YAACOBI, Y. ET AL: "Prevention of postoperative abdominal adhesions by tissue precoating with polymer solutions", JOURNAL OF SURGICAL RESEARCH, vol. 55, no. 4, October 1993 (1993-10-01), pages 422 - 426, XP000952885 *

Also Published As

Publication number Publication date
EP1148886A2 (fr) 2001-10-31
JP2002536323A (ja) 2002-10-29
WO2000045804A2 (fr) 2000-08-10
CA2361572A1 (fr) 2000-08-10
AU3356600A (en) 2000-08-25

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