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WO1998052620A3 - Collagen-like polymers with cell binding activity - Google Patents

Collagen-like polymers with cell binding activity Download PDF

Info

Publication number
WO1998052620A3
WO1998052620A3 PCT/EP1998/002857 EP9802857W WO9852620A3 WO 1998052620 A3 WO1998052620 A3 WO 1998052620A3 EP 9802857 W EP9802857 W EP 9802857W WO 9852620 A3 WO9852620 A3 WO 9852620A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
biopolymer
bulk material
collagen
polymers
Prior art date
Application number
PCT/EP1998/002857
Other languages
French (fr)
Other versions
WO1998052620A2 (en
Inventor
John Gerard Steele
Graham Johnson
Murray Goodman
Hans Joerg Griesser
Keith Michael Mclean
Gerrit Jan Beumer
Original Assignee
Novartis Ag
Commw Scient Ind Res Org
John Gerard Steele
Graham Johnson
Murray Goodman
Hans Joerg Griesser
Keith Michael Mclean
Gerrit Jan Beumer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO6842A external-priority patent/AUPO684297A0/en
Priority claimed from AUPO6862A external-priority patent/AUPO686297A0/en
Application filed by Novartis Ag, Commw Scient Ind Res Org, John Gerard Steele, Graham Johnson, Murray Goodman, Hans Joerg Griesser, Keith Michael Mclean, Gerrit Jan Beumer filed Critical Novartis Ag
Priority to JP54991998A priority Critical patent/JP2001527451A/en
Priority to AU80174/98A priority patent/AU8017498A/en
Priority to EP98928267A priority patent/EP0983096A2/en
Priority to CA002286687A priority patent/CA2286687A1/en
Publication of WO1998052620A2 publication Critical patent/WO1998052620A2/en
Publication of WO1998052620A3 publication Critical patent/WO1998052620A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention is essentially directed to a biocompatible material comprising a bulk material which has covalently bound to a surface or surfaces thereof one or more biopolymer compounds, said biopolymer compounds comprising at least one peptoid residue. The biopolymer compounds are most preferably polymer compounds comprising the sequence of the formula (I): -(Gly-Pro-Nleu)(Y)-, wherein (y) denotes ≥9. Also disclosed is a method of binding biopolymer compounds to a bulk material, which biopolymer compounds comprise at least one peptoid residue, as well as primary amine groups, the method comprising the steps of: (a) providing aldehyde or carboxyl groups on a surface or surfaces of said bulk material; (b) reacting said primary amine groups with aldehyde or carboxyl groups to form covalent bonds.
PCT/EP1998/002857 1997-05-16 1998-05-14 Collagen-like polymers with cell binding activity WO1998052620A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP54991998A JP2001527451A (en) 1997-05-16 1998-05-14 Collagen-like polymer with cell binding activity
AU80174/98A AU8017498A (en) 1997-05-16 1998-05-14 Collagen-like polymers with cell binding activity
EP98928267A EP0983096A2 (en) 1997-05-16 1998-05-14 Collagen-like polymers with cell binding activity
CA002286687A CA2286687A1 (en) 1997-05-16 1998-05-14 Collagen-like polymers with cell binding activity

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU6842/97 1997-05-16
AUPO6842A AUPO684297A0 (en) 1997-05-16 1997-05-16 Biocompatible materials
AU6862/97 1997-05-16
AUPO6862A AUPO686297A0 (en) 1997-05-16 1997-05-16 Collagen-like polymers with cell binding activity

Publications (2)

Publication Number Publication Date
WO1998052620A2 WO1998052620A2 (en) 1998-11-26
WO1998052620A3 true WO1998052620A3 (en) 1999-02-25

Family

ID=25645423

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/002857 WO1998052620A2 (en) 1997-05-16 1998-05-14 Collagen-like polymers with cell binding activity

Country Status (5)

Country Link
EP (1) EP0983096A2 (en)
JP (1) JP2001527451A (en)
AU (1) AU8017498A (en)
CA (1) CA2286687A1 (en)
WO (1) WO1998052620A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR021240A1 (en) * 1998-11-13 2002-07-03 Commw Scient Ind Res Org COUPLED PEPTIDES
EP1297010A2 (en) * 2000-06-23 2003-04-02 Bioelastics Research, Ltd. Bioelastomer nanomachines and biosensors
WO2002094856A2 (en) 2001-05-24 2002-11-28 Neuronz Limited Gpe analogs and peptidomimetics
US7714020B2 (en) 2001-05-24 2010-05-11 Neuren Pharmaceuticals Limited Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate
US7605177B2 (en) 2001-05-24 2009-10-20 Neuren Pharmaceuticals Limited Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration
US20030045942A1 (en) * 2001-09-05 2003-03-06 Lai Wen-Fu T. Regenerative bone implants
EP1364663A1 (en) * 2002-05-21 2003-11-26 Commonwealth Scientific And Industrial Research Organisation Ocular devices with functionalized surface with adhesive properties
JP4705319B2 (en) * 2002-07-19 2011-06-22 三洋化成工業株式会社 Wound dressing
EP2183280B1 (en) 2007-08-01 2011-10-26 Ethicon, Inc. Collagen-related peptides and uses thereof
JP5388090B2 (en) * 2008-05-29 2014-01-15 国立大学法人東北大学 Preparation method of corneal transplant material by scleral transparency
US20100021527A1 (en) 2008-07-25 2010-01-28 Chunlin Yang Collagen-related peptides and uses thereof and hemostatic foam substrates

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0109061A1 (en) * 1982-11-10 1984-05-23 Achim Dr. Engelhardt Implants and process for their production
EP0290642A1 (en) * 1987-05-12 1988-11-17 Mittermayer, Christian, Dr. med. Method for seeding polymeric surfaces with human endothelial cells
EP0531547A1 (en) * 1991-03-29 1993-03-17 Vascular Graft Research Center Co., Ltd. Composite artificial blood vessel
WO1993011781A1 (en) * 1991-12-09 1993-06-24 The Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
WO1997019106A2 (en) * 1995-11-17 1997-05-29 The Regents Of The University Of California Collagen-like peptoid residue-containing structures

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0109061A1 (en) * 1982-11-10 1984-05-23 Achim Dr. Engelhardt Implants and process for their production
EP0290642A1 (en) * 1987-05-12 1988-11-17 Mittermayer, Christian, Dr. med. Method for seeding polymeric surfaces with human endothelial cells
EP0531547A1 (en) * 1991-03-29 1993-03-17 Vascular Graft Research Center Co., Ltd. Composite artificial blood vessel
WO1993011781A1 (en) * 1991-12-09 1993-06-24 The Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
WO1997019106A2 (en) * 1995-11-17 1997-05-29 The Regents Of The University Of California Collagen-like peptoid residue-containing structures

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
M. GOODMAN ET AL: "Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu). 6. Conformational Analysis of Gly-Pro-Nleu Sequences by 1H NMR, CD, and Molecular Modeling", J.AM.CHEM.SOC, vol. 118, no. 44, 1996, USA, pages 10725 - 10732, XP002085339 *
SIMON R J ET AL: "PEPTOIDS: A MODULAR APPROACH TO DRUG DISCOVERY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 89, October 1992 (1992-10-01), pages 9367 - 9371, XP002036760 *

Also Published As

Publication number Publication date
EP0983096A2 (en) 2000-03-08
CA2286687A1 (en) 1998-11-26
JP2001527451A (en) 2001-12-25
WO1998052620A2 (en) 1998-11-26
AU8017498A (en) 1998-12-11

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