WO1996040087A3 - Pressure sensitive acrylate adhesive composition cross-linked with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group - Google Patents
Pressure sensitive acrylate adhesive composition cross-linked with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group Download PDFInfo
- Publication number
- WO1996040087A3 WO1996040087A3 PCT/US1996/008492 US9608492W WO9640087A3 WO 1996040087 A3 WO1996040087 A3 WO 1996040087A3 US 9608492 W US9608492 W US 9608492W WO 9640087 A3 WO9640087 A3 WO 9640087A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pressure sensitive
- linked
- hydroxyl group
- drug
- sensitive acrylate
- Prior art date
Links
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 title abstract 3
- 239000000853 adhesive Substances 0.000 title abstract 3
- 230000001070 adhesive effect Effects 0.000 title abstract 3
- XBIUWALDKXACEA-UHFFFAOYSA-N 3-[bis(2,4-dioxopentan-3-yl)alumanyl]pentane-2,4-dione Chemical compound CC(=O)C(C(C)=O)[Al](C(C(C)=O)C(C)=O)C(C(C)=O)C(C)=O XBIUWALDKXACEA-UHFFFAOYSA-N 0.000 title abstract 2
- 125000003118 aryl group Chemical group 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 title abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229930182833 estradiol Natural products 0.000 abstract 1
- 238000013271 transdermal drug delivery Methods 0.000 abstract 1
- 238000004383 yellowing Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU60326/96A AU6032696A (en) | 1995-06-07 | 1996-06-03 | Pressure sensitive acrylate adhesive composition cross-linke d with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48429495A | 1995-06-07 | 1995-06-07 | |
US08/484,294 | 1995-06-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996040087A2 WO1996040087A2 (en) | 1996-12-19 |
WO1996040087A3 true WO1996040087A3 (en) | 1997-01-30 |
Family
ID=23923554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1996/008492 WO1996040087A2 (en) | 1995-06-07 | 1996-06-03 | Pressure sensitive acrylate adhesive composition cross-linked with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU6032696A (en) |
WO (1) | WO1996040087A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7309497B2 (en) | 2000-08-24 | 2007-12-18 | Schwarz Pharma Ag | Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients |
US7632859B2 (en) | 2002-12-02 | 2009-12-15 | Schwarz Pharma Ag | Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease |
US9186335B2 (en) | 2002-07-30 | 2015-11-17 | Ucb Pharma Gmbh | Hot melt TTS for administering rotigotine |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU228434B1 (en) * | 1995-06-07 | 2013-03-28 | Ortho Mcneil Pharm Inc | Transdermal medicament for administering 17-deacetyl norgestimate alone or in combination with an estrogen |
DE19706824C1 (en) * | 1997-02-21 | 1998-03-26 | Lohmann Therapie Syst Lts | Plaster for transdermal drug delivery |
DE19814084B4 (en) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2 agonist-containing transdermal therapeutic system for the treatment of Parkinson's syndrome and process for its preparation |
DE10000333A1 (en) * | 2000-01-07 | 2001-07-19 | Lohmann Therapie Syst Lts | Pharmaceutical composition for the transdermal administration of hormones with a permeation-improving additive |
EP1311559B1 (en) * | 2000-06-01 | 2006-08-02 | Kraton Polymers Research B.V. | Compositions comprising a functionalized block copolymer crosslinked with aluminum acetylacetonate |
DE10157745A1 (en) * | 2001-11-24 | 2003-06-26 | Hf Arzneimittelforsch Gmbh | Transdermal therapeutic system for the administration of 17alpha-estradiol |
US6653408B1 (en) | 2002-11-21 | 2003-11-25 | Kraton Polymers U.S. Llc | Compositions comprising a functionalized block copolymer crosslinked with aluminum acetylacetonate |
US7816546B2 (en) | 2003-06-30 | 2010-10-19 | Richter Gedeon Vegyeszeti Gyar Rt. | Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime |
DE10333393A1 (en) * | 2003-07-23 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with the active ingredient pramipexole |
KR102416487B1 (en) | 2014-07-04 | 2022-07-04 | 루예 파마 아게 | Device for the manufacture of pharmaceutical patches |
CA3010183A1 (en) | 2015-12-30 | 2017-07-06 | Corium International, Inc. | Systems and methods for long term transdermal administration |
AU2017281789B2 (en) | 2016-06-23 | 2023-04-13 | Corium, LLC. | Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent |
KR20230097203A (en) | 2016-07-27 | 2023-06-30 | 코리움, 엘엘씨 | Donepezil transdermal delivery system |
EP3490559A1 (en) | 2016-07-27 | 2019-06-05 | Corium International, Inc. | Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery |
RU2764764C2 (en) | 2016-07-27 | 2022-01-21 | Кориум Интернэшнл, Инк. | Transdermal memantine delivery systems |
CA3086163A1 (en) | 2017-12-20 | 2019-06-27 | Corium, Inc. | Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point |
CN113227291B (en) | 2018-11-08 | 2023-03-21 | 艾利丹尼森公司 | Yellowing-resistant PSA |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0435200A2 (en) * | 1989-12-28 | 1991-07-03 | Nitto Denko Corporation | Estrogen-containing gel preparation |
US5204109A (en) * | 1989-12-28 | 1993-04-20 | Nitto Denko Corporation | Percutaneous gel preparation |
US5240711A (en) * | 1989-11-29 | 1993-08-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system comprising as active component buprenorphine |
US5298258A (en) * | 1989-12-28 | 1994-03-29 | Nitto Denko Corporation | Acrylic oily gel bioadhesive material and acrylic oily gel preparation |
US5306503A (en) * | 1990-06-25 | 1994-04-26 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Patch with a high content of softening ingredients |
-
1996
- 1996-06-03 WO PCT/US1996/008492 patent/WO1996040087A2/en active Application Filing
- 1996-06-03 AU AU60326/96A patent/AU6032696A/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5240711A (en) * | 1989-11-29 | 1993-08-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system comprising as active component buprenorphine |
EP0435200A2 (en) * | 1989-12-28 | 1991-07-03 | Nitto Denko Corporation | Estrogen-containing gel preparation |
US5204109A (en) * | 1989-12-28 | 1993-04-20 | Nitto Denko Corporation | Percutaneous gel preparation |
US5298258A (en) * | 1989-12-28 | 1994-03-29 | Nitto Denko Corporation | Acrylic oily gel bioadhesive material and acrylic oily gel preparation |
US5306503A (en) * | 1990-06-25 | 1994-04-26 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Patch with a high content of softening ingredients |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7309497B2 (en) | 2000-08-24 | 2007-12-18 | Schwarz Pharma Ag | Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients |
US9186335B2 (en) | 2002-07-30 | 2015-11-17 | Ucb Pharma Gmbh | Hot melt TTS for administering rotigotine |
US7632859B2 (en) | 2002-12-02 | 2009-12-15 | Schwarz Pharma Ag | Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease |
Also Published As
Publication number | Publication date |
---|---|
AU6032696A (en) | 1996-12-30 |
WO1996040087A2 (en) | 1996-12-19 |
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