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WO1991008771A3 - Procede de culture intensive, in vitro, de souches de babesia divergens, procede de preparation d'exoantigenes et vaccin contenant ces antigenes - Google Patents

Procede de culture intensive, in vitro, de souches de babesia divergens, procede de preparation d'exoantigenes et vaccin contenant ces antigenes Download PDF

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Publication number
WO1991008771A3
WO1991008771A3 PCT/FR1990/000934 FR9000934W WO9108771A3 WO 1991008771 A3 WO1991008771 A3 WO 1991008771A3 FR 9000934 W FR9000934 W FR 9000934W WO 9108771 A3 WO9108771 A3 WO 9108771A3
Authority
WO
WIPO (PCT)
Prior art keywords
exoantigens
antigens
preparing
strains
intensive
Prior art date
Application number
PCT/FR1990/000934
Other languages
English (en)
Other versions
WO1991008771A2 (fr
Inventor
Joseph Schrevel
Andre Gorenflot
Eric Precigout
Alain Marchand
Philippe Brasseur
Hostis Monique L
Daniel Rigomier
Alexis Francois Marie Valentin
Emmanuel Vidor
Guy Bissuel
Original Assignee
Rhone Merieux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Merieux filed Critical Rhone Merieux
Publication of WO1991008771A2 publication Critical patent/WO1991008771A2/fr
Publication of WO1991008771A3 publication Critical patent/WO1991008771A3/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/947Microorganisms using protozoa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne un procédé de culture de Babesia divergens, caractérisé en ce que la souche de Babesia est maintenue en culture sur un milieu de culture exempt de protéine sérique mais contenant des lipoprotéines ainsi que des hématies, ainsi qu'un procédé de préparation d'exoantigènes et un vaccin contenant ces antigènes.
PCT/FR1990/000934 1989-12-20 1990-12-20 Procede de culture intensive, in vitro, de souches de babesia divergens, procede de preparation d'exoantigenes et vaccin contenant ces antigenes WO1991008771A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR89/16890 1989-12-20
FR898916890A FR2655853B1 (fr) 1989-12-20 1989-12-20 Procede de culture intensive, in vitro, de souches de babesia divergens, procede de preparation d'exoantigenes et vaccin contenant ces antigenes.

Publications (2)

Publication Number Publication Date
WO1991008771A2 WO1991008771A2 (fr) 1991-06-27
WO1991008771A3 true WO1991008771A3 (fr) 1991-08-08

Family

ID=9388758

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1990/000934 WO1991008771A2 (fr) 1989-12-20 1990-12-20 Procede de culture intensive, in vitro, de souches de babesia divergens, procede de preparation d'exoantigenes et vaccin contenant ces antigenes

Country Status (8)

Country Link
US (1) US5290688A (fr)
EP (1) EP0460177A1 (fr)
AU (1) AU641723B2 (fr)
FR (1) FR2655853B1 (fr)
IE (1) IE904638A1 (fr)
PT (1) PT96273A (fr)
WO (1) WO1991008771A2 (fr)
ZA (1) ZA9010116B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724392B1 (fr) * 1994-09-08 1996-12-13 Virbac Lab Procedes de culture, d'attenuation de la virulence et de clonage in vitro de parasites du genre babesia et leurs applications

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0018579A2 (fr) * 1979-04-30 1980-11-12 University of Illinois Foundation Antigène de la babésiose, vaccin et réactif de diagnostic le contenant
FR2608926A1 (fr) * 1986-12-24 1988-07-01 Secr Agricult Nord Irland Antigene de babesia divergens, procede pour le produire et vaccin le contenant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4055466A (en) * 1973-07-09 1977-10-25 Johnson & Johnson Culture medium for tissue culture techniques
GB2062463B (en) * 1979-11-06 1983-11-23 Commw Scient Ind Res Org Babesiosis vaccine
US4767622A (en) * 1983-08-19 1988-08-30 University Of Illinois Method and materials for development of immunological responses protective against malarial infection
FR2589063B1 (fr) * 1985-10-24 1988-08-26 Rhone Merieux Procede de culture de babesia canis, application a la preparation d'antigenes et de vaccins, et antigenes et vaccins contre la piroplasmose
ZA902546B (en) * 1989-04-04 1991-04-24 Univ Florida Novel proteins and cloned genes for diagnosis and prophylaxis of babesiosis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0018579A2 (fr) * 1979-04-30 1980-11-12 University of Illinois Foundation Antigène de la babésiose, vaccin et réactif de diagnostic le contenant
FR2608926A1 (fr) * 1986-12-24 1988-07-01 Secr Agricult Nord Irland Antigene de babesia divergens, procede pour le produire et vaccin le contenant

Also Published As

Publication number Publication date
WO1991008771A2 (fr) 1991-06-27
ZA9010116B (en) 1991-09-25
FR2655853B1 (fr) 1994-06-10
EP0460177A1 (fr) 1991-12-11
FR2655853A1 (fr) 1991-06-21
AU7054791A (en) 1991-07-18
IE904638A1 (en) 1991-07-17
AU641723B2 (en) 1993-09-30
US5290688A (en) 1994-03-01
PT96273A (pt) 1991-09-30

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