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US3921857A - Non-spitting liquid dispensing device - Google Patents

Non-spitting liquid dispensing device Download PDF

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Publication number
US3921857A
US3921857A US419966A US41996673A US3921857A US 3921857 A US3921857 A US 3921857A US 419966 A US419966 A US 419966A US 41996673 A US41996673 A US 41996673A US 3921857 A US3921857 A US 3921857A
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United States
Prior art keywords
liquid
source
piston
dispensing
dispenser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US419966A
Inventor
Pasquale R Riccio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Corp
Original Assignee
Ciba Geigy Corp
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Filing date
Publication date
Application filed by Ciba Geigy Corp filed Critical Ciba Geigy Corp
Priority to US419966A priority Critical patent/US3921857A/en
Priority to CH1430574A priority patent/CH588896A5/xx
Priority to SE7413599A priority patent/SE7413599L/xx
Priority to NL7414127A priority patent/NL7414127A/en
Priority to AR25632174A priority patent/AR210252A1/en
Priority to DE19742451367 priority patent/DE2451367C3/en
Priority to FR7436146A priority patent/FR2257352B1/fr
Priority to DE19742462461 priority patent/DE2462461A1/en
Priority to IT5380974A priority patent/IT1032113B/en
Priority to CA212,645A priority patent/CA1008033A/en
Priority to AU74866/74A priority patent/AU495580B2/en
Priority to DK566374A priority patent/DK142132B/en
Priority to BE150044A priority patent/BE821667A/en
Priority to GB2872577A priority patent/GB1493615A/en
Priority to GB4718174A priority patent/GB1493614A/en
Priority to JP12498774A priority patent/JPS5078912A/ja
Application granted granted Critical
Publication of US3921857A publication Critical patent/US3921857A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/60Contents and propellant separated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/28Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with stationary measuring chambers having constant volume during measurement
    • G01F11/30Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with stationary measuring chambers having constant volume during measurement with supply and discharge valves of the lift or plug-lift type
    • G01F11/32Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with stationary measuring chambers having constant volume during measurement with supply and discharge valves of the lift or plug-lift type for liquid or semiliquid

Definitions

  • the device has a dispenser body, with an aspirating nozzle opening out of the body and having a 52] US. Cl. 222/145; 222/193; 239/357 Femral hmugh Passage and laieral Passages Opening 51] 1m. 01. B67D 5/54 the through F- The QSpenser body has [58] Field of Search 222/129, 145, 193, 398, a Supply chamber Passage? 222/401 402, 387; 239/308 317 350, 357 are connected.
  • a dispensing device having a source of gas under pressure and a source of liquid to be dispensed which can be under pressure or not, and a dispensing nozzle, of the Venturi type, which has a central through passage from a an annular mixing chamber around the nozzle.
  • the device has a product flow path from the source of liquid under pressure which opens into the mixing chamber, and has a compressed gas flow path from the source of compressed gas which has branches opening into the central through passage of the nozzle and into the mixing chamber.
  • FIG. 1 is a sectional elevation view of a dispenser according to the present invention with the parts in the rest or non-dispensing positions;
  • FIG. 2 is a sectional elevation view similar to FIG. 1 with the parts in the dispensing positions;
  • FIG. 3 is an elevation view, on a reduced scale, of the device of FIGS. 1 and 2;
  • FIG. 4 is a sectional elevation view of the alternative form of the source of liquid to be dispensed.
  • a dispenser body 10 in a dispenser body 10 is an upwardly open recess 1 1 having a cross-sectional shape complementary to the cross-sectional shape of a lower body member 31 of a measured dose dispenser which is a source of liquid to be dispensed and which will be described below.
  • the lower body member 31 fits into recess 11 in slidable relationshiptherewith.
  • a further recess 12 is provided in the bottom of the recess 11 which has a cross-sectional shape complementary to the cross-sectional shape of the hollow stem portion 37 of the measured dose dispenser and which receives the hollow stem portion 37 in a substantially fluid tight fit with the end of the stem portion 37 in the bottom of the recess 12 and with the parts in the rest or non-dispensing positions as seen in FIG. 1, with the lower end of the lower body member 31 spaced above the bottom of the recess 11.
  • Nozzle means 13 in the form of a nozzle insert 14 opens out of the side of the dispensing body 10.
  • the nozzle insert 14 is positioned in a laterally opening recess 16 in the dispenser body which is shaped to leave a an annular mixing chamber 17 around the nozzle insert.
  • the nozzle insert has a Venturi passage 14a therethrough which has lateral passages 14b extending from the mixing chamber into the Venturi passage 14a.
  • the recess 16 has a smaller diameter portion at the inner end and a larger diameter portion at the outer end and the nozzle insert 14 has a smaller diameter portion which fits into the smaller diameter portion of the recess but is longerthan this portion is deep.
  • the larger diameter portion of the nozzle insert is thus spaced outwardly of the bottom of the larger portion of recess 16 to leave the mixing chamber 17.
  • the dispenser body has a liquid product flow path therethrough in the form of a passage from the recess 12 to the mixing chamber 17 around the nozzle insert 14.
  • a source of gas under pressure in the form of an air compressing piston cylinder means is provided on the opposite end of the body 10 from the measured dose dispenser, and in the embodiment disclosed comprises a cylinder 18 which extends downwardly from the body 10 and within which a piston 19 is slidably positioned. Gasket 19a seals the piston in its movement into the cylinder 18.
  • a return spring 20 within the cylinder 18 urges the piston 19 out of the cylinder 18. Opening out of the inner end of the cylinder 18 and into the body 10 is a recess 21, and from the recess 21 a compressed air path is provided which has a vertically extending portion 22 and one horizontal branch 23 extending to the central passage of the nozzle insert and a second horizontal branch 24 extending to the mixing chamber 17.
  • the recess 21 and the air path portions comprise a compressed air flow path through the body 10.
  • a compressed air controlling poppet valve member 25 which seats on a seat 26 retained in the recess 21 by a retainer 27 which is positioned in the inner end of the cylinder 18.
  • a valve return spring 28 in the recess 21 holds the poppet valve on the seat 26.
  • An actuating pin 29 extends upwardly from the piston 19. At the inner end of the stroke of the piston 19, it is engaged with the poppet valve member 25 to lift the poppet valve member 25 from the seat 26 sufficiently far to pass compressed air into the recess 21.
  • the measured dose dispenser in this embodiment is in a form in which it is a source of pressurized liquid. It comprises a piston-cylinder means generally indicated at 30 in which the lower body member 31 is in the form of a piston over which a cylinder 32 is slidable. A gasket 32a in the end of the lower body member 31 seals against the inside surface of the cylinder 32 as the cylinder slides along the piston.
  • the lower body member, 31 is made up of an outer shell 33 within which is positioned an inner body 34.
  • the end of the shell 33 has an aperture 33a therein and on the inside of the shell between the bottom thereof and the end of the inner body 34 is a first annular sealing gasket 35.
  • the inner body 34 has a larger diameter recess 34a in the end toward the bottom of the shell, and has a smaller diameter bore 34b extending from the inner end of the recess 34a to the end of the lower body member which is within the cylinder 32.
  • a metering valve stem Movably mounted within the recess 34a and bore 34b is a metering valve stem generally indicated at 36 which has a solid stem portion within the recess 34a and has the hollow stern portion 37 extending from the solid stem portion out through the first annular sealing gasket 35 and the apertures 33a in the bottom of the shell 33, the outside surface of the hollow stem portion 37 being in sealing relationship with the first annular sealing gasket 35.
  • a flange 38 which in the rest position of the stem, as shown in FIG. 1, rests on the first annular gasket 35.
  • the cross-sectional shape of the solid stem portion is such that it will move freely into the bore 34b.
  • a second annular sealing gasket 40 Around the end of the bore 34b where it opens into the larger diameter recess 34a is a second annular sealing gasket 40 through which the solid portions of the stem can move in sealing relationship therewith when the stem 36 is raised.
  • a spring 39 is positioned between the second annular sealing gasket 40 and the flange 38, and urges the flange toward the first annular sealing gasket 35.
  • an aperture 37b which in the rest position of the device as shown in FIG. 1 is below or outside the bottom of the lower body member 31. In the dispensing position this aperture is within the larger diameter recess 34a.
  • valve stem 36 and the inner body 34 with its larger diameter recess 34a, the annular sealing gaskets 35 and 40, and the spring 39 form a simple metering stem which is known from the aerosol dispensing art and is shown in US. Pat. no. 2,721,010.
  • the measured dose dispenser is caused to operate to dispense a squirt of liquid through the hollow stem portion 37 into the product flow path 15 and into the mixing chamber 17.
  • air is compressed in the cylinder 18, ahead of the piston 19.
  • the poppet valve 25 remains closed.
  • the actuating pin 29 hits the poppet valve 25
  • the poppet valve is lifted from the seat 26, as shown in FIG.
  • the air compressed in the cylinder 18 is suddenly released to flow through the compressed air path both to the mixing chamber 17 around the nozzle insert 14 and through the central Venturi passage of the nozzle insert.
  • the compressed air flowing into the mixing chamber 17 mixes with and exerts a shearing effect on the liquid under pressure from the metered dose dispenser so as to break up the liquid, and this mixture is drawn through the lateral passages 18 into the stream of gas under pressure which is flowing through the center of the nozzle insert.
  • the liquid is subjected to further break up in the Venturi passage and is immediately dispensed from the nozzle insert as a fine spray of dropletsof the liquid in compressed air without there first being ejected relatively large droplets of liquid.
  • valve means of the measured dose dispenser acts to control the flow of the liquid product from the liquid supply in a simple and effective manner and independently of the air valve controlling the flow of the compressed air from the air compressing piston cylinder means.
  • metered dose dispensing device has been shown as one specific source of pressurized liquid, other sources can also be provided, such as are disclosed in the above mentioned copending application Ser. No. 496,282.
  • piston-cylinder air pressurizing means have been described as a specific source of gas under pressure, other sources could be provided, for example a valved conventional aerosol can containing a conventional propellant under pressure.
  • the source of liquid can be a source which does not supply liquid under pressure, i.e., can be a source which simply presents to the system the source of liquid so that the liquid is aspirated by the reduced pressure in the system caused by the compressed air flowing through the Venturi passage in the nozzle 14.
  • FIG. 4 shows the structure thereof and only a part of the structure of the remainder of the device.
  • the source of liquid 41 has an outer casing '43 which fits into the recess 1 1 in the dispenser body in the same manner as does the source 30.
  • a cover 430 Over the upper end of the casing 43. Wlthin the casing 43 is an inner body 44.
  • the end of the casing 43 has an aperture 43a therein and on the inside of the casing between the bottom thereof and the end of the inner body 44 is a first annular sealing gasket 45.
  • the inner body 44 has a larger diameter recess 44a in the end toward the bottom of the casing 43 and has a smaller diameter bore 44b extending from the inner end of the recess 44a to the end of the inner body 44 which is within the upper part of the casing 43.
  • a nipple 44c projects upwardly from the end of the smaller diameter bore 44b.
  • a metering valve stem Movably mounted within the recess 44a and bore 44b is a metering valve stem generally indicated at 46 which has a solid stem portion within the recess 44a and has a hollow stem portion 47 extending from the solid stem portion out through the first annular sealing gasket 45 and the aperture 43a in the bottom of the casing 43, the outside surface of the hollow stemportion 47 being in sealing relationship with the first annular sealing gasket 45.
  • a flange 48 which in the rest position of the stem, as shown in FIG. 4, rests on the first annular gasket 45.
  • the cross-sectional shape of the solid stem portion is such that it will move freely into the bore 44b.
  • a second annular sealing gasket 50 Around the end of the bore 44b where it opens intothe larger diameter recess 44a is a second annular sealing gasket 50 through which'the solid portion of the stern can move in sealing relationship therewith when the .stem 46 is raised.
  • a spring 49 is positioned between the second annular sealing gasket 50 and the flange 48, and urges the flange toward the first annular sealing gasket 45.
  • an aperture 4712 which in the rest position of the device as shown in FIG. 4 is below or outside the bottom of the casing 43. In the dispensing position this aperture is within the larger diameter recess 44a.
  • valve stem 46 and the inner body 44 with its larger diameter recess 44a, the annular sealing gaskets 45 and 50, and the spring 49 form a simple metering stem which is known from the aerosol dispensing art and is shown in US. Pat. No. 2,72l,010
  • a flexible bag 51 filled with liguid L is positioned within the upper end of casing 43 with the mouth in liquid tight engagement with the nipple 440.
  • An aperture or vent 43d is provided in casing 43 opening into the space containing the bag.
  • the measured dose dispenser exposes a measured amount of liquid through the hollow stem portion 47, the product flow path 15 and the mixing chamber 17.
  • air is compressed in the cylinder 18, ahead of the piston 19.
  • the poppet valve 25 remains closed.
  • the actuating pin 29 hits the poppet valve 25
  • the poppet valve is lifted from the seat 26, as shown in FIG. 2, and the air compressed in the cylinder 18 is suddenly released to flow through the compressed air path both to the mixing chamber 17 around the nozzle insert 14 and through the central Venturi passage of the nozzle insert.
  • Compressed air flowing through the Venturi passage 14a aspirates the measured amount of liquid from the source 41 and draws it into the mixing chamber 17.
  • the compressed air flowing into the supply chamber 17 mixes with and exerts a shearing effect on the liquid from the metered dose dispenser so as to break up the liquid, and this mixture is drawn through the lateral openings 18 into the stream of gas under pressure which is flowing through the center of the nozzle insert.
  • the liquid is subjected to further break up in the Venturi passage and is immediately dispensed from the nozzle insert as a fine spray of droplets of the liquid in compressed air without there first being ejected relatively large droplets of liquid.
  • the source of liquid as described above can also be resupplied simply be replacing the throwaway measured dose dispensing device.
  • the valve means of the measured dose dispenser acts to control the flow of the liquid product from the liquid supply in a simple and effective manner and independently of the air valve controlling the flow of the compressed air from the air compressing piston cylinder means, and also blocks flow of compressed air back into the bag 51.
  • a device for dispensing a spray of the fine droplets of liquid in gas comprising a dispenser body, said dispenser body having a nozzle means opening out of said body and having a central Venturi passage therethrough and lateral passages opening into said Venturi passage, said dispenser body having an annular mixing chamber around said central passage to which said lateral passages are connected, a source of liquid to be dispensed having means for mechanically pressurizing said liquid and operatively associated with said dispenser body valve means controlling dispensing of liquid from said source; said dispenser body having a product flow conduit therethroug from said valve means for said source of liquid to said annular mixing chamber and a source of gas under pressure and opening axially into the central Venturi passage of said nozzle means, and a branch compressed gas flow conduit branching from said main compressed gas flow conduit and opening into said annular mixing chamber at a point spaced from the point at which said product flow conduit opens into said annular mixing chamber.
  • a device as claimed in claim 1 in which said source of liquid comprises a measured dose dispenser having a piston-cylinder means containing the liquid to be dispensed, and said valve means is a measured dose dispensing valve means for dispensing a measured dose of the liquid when the piston-cylinder means is actuated.
  • a device as claimed in claim 1 in which said source of compressed gas comprises an air compressing piston-cylinder means having a fixed member and a movable member movable through a compressing stroke, relative to the fixed member and a compressed air controlling valve member in said compressed air flow path normally closing said path, actuating pin means operatively associated with said air compressing piston-cylinder means and said compressed air controlling valve member for actuating said compressed air valve member to open it near the end of the compression stroke.
  • said source of liquid comprises a dispenser having a liquid pressurizing piston-cylinder means containing the liquid to be dispensed
  • said valve means is a measured dose dispensing valve means for dispensing an amount of the liquid when the liquid pressurizing piston-cylinder means is actuated, said air compressing piston-cylinder means being on one end of said dispenser body and the liquid pressurizing piston-cylinder means being on the other end of said dispenser body, whereby pressure on the opposite ends of said device actuates both pistoncylinder means.
  • a device as claimed in claim 1 in which said source of liquid is a source of unpressurized liquid and comprises a measured dose dispenser having a container for the liquid which is at atmospheric pressure, and said valve means is a measured dose dispensing valve means for permitting aspiration of a measured dose of the liquid when said valve means is actuated.

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  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

A device for dispensing a spray of fine droplets of liquid in gas. The device has a dispenser body, with an aspirating nozzle opening out of the body and having a central through passage and lateral passages opening into the through passage. The dispenser body also has a supply chamber therein to which the lateral passages are connected. A source of liquid to be dispensed is operatively associated with the dispenser body and the dispenser body has a valved product flow path therethrough from the source of liquid to the supply chamber. A source of gas under pressure is also operatively associated with the body and the body has a branched compressed gas flow path therethrough from the source of gas under pressure to the central through passage of the nozzle and to the supply chamber.

Description

United States Patent Riccio 1 Nov. 25, 1975 [54] NON-SPITTING LIQUID DISPENSING 3,788,556 l/l974 Riccio 239/357 X DEVICE [75] Inventor: Pasquale R. Riccio, Salem, N.l-l. gfg g fg liggg ii 13 2 [73] Assignee: Ciba-Geigy Corporation, Ardsley, Attorney, Agent, or FirmWenderoth. Lind & Ponack NY. 22 Filed: Nov. 29, 1973- [57] .ABSTRACT A dev1ce for dlspensmg a spray of fine droplets of l1q- PP 419,966 uid in gas. The device has a dispenser body, with an aspirating nozzle opening out of the body and having a 52] US. Cl. 222/145; 222/193; 239/357 Femral hmugh Passage and laieral Passages Opening 51] 1m. 01. B67D 5/54 the through F- The QSpenser body has [58] Field of Search 222/129, 145, 193, 398, a Supply chamber Passage? 222/401 402, 387; 239/308 317 350, 357 are connected. A source of l1qu1d to be dlspensed 1s 418, 365 366 367 operatively associated with the dispenser body and the dispenser body has a valved product flow path there- [56] References Cited LhrouAgh from thfe sourc:i of liquid to thel supply charrlier. source 0 gas un er pressure 1s a so operat1ve y UNITED STATES PATENTS associated with the body and the body has a branched 3,109,546 11/1963 Baruh 222/453 x compressed gas fl path therethrough f the 3,415,425 12/1968 Kn ghtet al. 222/387 x Source of gas under pressure to the central through passage of the nozzle and to the supply chamber.
3,741,443 6/1973 Marand 222/145 5 Claims, 4 Drawing Figures U.S. Patsnt Nov. 25, 1975 3,921,857
NON-SPITTING LIQUID DISPENSING DEVICE BACKGROUND AND PRIOR ART For many years, most of the aerosol dispensers have been the type in which a propellant is compressed in a valved container along with the product to be dispensed, so that when the valve is opened, the pressure of the propellant forces the product, mixed with the propellant, through the valve and out through a nozzle means, and because of the high pressure of the propellant, the mixed product and propellant emerge from the nozzle in spray form. Because of the high pressure, the start of flow of the mixed propellant and product is almost instantaneous and little or no trouble is experienced because of larger drops of liquid first being ejected followed by a fine spray; Such a difficulty will hereinafter be referred to as spitting.
In the last few years, there has been developed a type of aerosol dispenser in which the propellant is stored in the dispensing apparatus separately from the product to be dispensed, the propellant and product being mixed only upon being actually dispensed. This'has enabled the dispensing by means of aerosol dispensers, of products which are normally incompatible with the propellants being used when the two are stored together for any length of time. However, this type of dispenser still utilizes a propellant as the means for dispensing and atomizing the product. Occasionaly this type of device is subject to spitting.
There has recently been much discussion about the possible damaging effects of the propellants commonly used in such aerosol dispensers, such as from freon gas. Where the products are not used on the human body, such as with paint or insecticide, precautions can be taken by the user so that he does not inhale the dispensed mixture of product and propellant. However, where the product is to be used on the human body or to be ingested into the human body, such as in the case of deodorant which is used directly on the body, or a breath freshner which is sprayed directly into the mouth, there is no way to avoid exposing the user to the damaging effects of the propellant.
This drawback in the aerosol dispensers has led to the recent development of dispensers which use a charge of compressed air to aspirate a product from a separate product container each time the dispenser is actuated. Examples of such dispensers are found in the US. Pat. Nos. 3,672,545 and 3,73 3,010. In these dispensers, since there is no propellant used, but only compressed air, there is no danger to the user from the propellant. These devices therefore have a great potential for use in dispensing such products as medicaments, cosmetic and personal hygiene products and the like where it is desirable that the user not be exposed to the dangers of conventional propellants. However, they are subject to the problem of spitting.
In addition, in US. application Ser. No. 496,282, filed Aug. 4, 1974, which is a continuation of Ser. No. 41 1,267, filed Oct. 31, 1973, now abandon, there is disclosed a dispenser device in which at the same time as the compressed air is produced by a piston-cylinder means, pressure is also exerted on the liquid product to be dispensed, so that at the time the compressed air is released the liquid product is supplied under pressure.
A similar device is disclosed in US. application Ser. No. 411,265, filed Oct. 31, 1973, now US. Pat. No. 3,878,973. These devices have made it possible to pro- 2 vide a spray with a droplet size which makes it possible to use these devices for medicaments which are to be inhaled by the user. However, the devices, disclosed in both applications are also subject to the problem of spitting.
OBJECTS AND BRIEF DESCRIPTION OF THE INVENTION It is an object of the present invention to provide a device for dispensing a spray of liquid in compressed gas in which the problem of spitting is avoided, and the device upon actuation immediately starts to dispense a spray of fine droplets without first ejecting larger droplets of the liquid to be dispensed.
It is a further object of the present invention to provide an arrangement in such a device which can be used with a variety of dispenser devices.
These objects are achieved by providing a dispensing device having a source of gas under pressure and a source of liquid to be dispensed which can be under pressure or not, and a dispensing nozzle, of the Venturi type, which has a central through passage from a an annular mixing chamber around the nozzle. The device has a product flow path from the source of liquid under pressure which opens into the mixing chamber, and has a compressed gas flow path from the source of compressed gas which has branches opening into the central through passage of the nozzle and into the mixing chamber. By this arrangement, the liquid to be dispensed is mixed with compressed gas to a certain extent prior to its being fed into the nozzle through the lateral passages, and the ejection of large droplets at the start of the flow of compressed gas and liquid under pressure is avoided.
BRIEF DESCRIPTIONS OF THE DRAWINGS The invention will now be described in greater detail in the following specification taken in connection with the accompanying drawings, in which:
FIG. 1 is a sectional elevation view of a dispenser according to the present invention with the parts in the rest or non-dispensing positions;
FIG. 2 is a sectional elevation view similar to FIG. 1 with the parts in the dispensing positions;
FIG. 3 is an elevation view, on a reduced scale, of the device of FIGS. 1 and 2; and
FIG. 4 is a sectional elevation view of the alternative form of the source of liquid to be dispensed.
DETAILED DESCRIPTION OF THE INVENTION Referring to the figures, in a dispenser body 10 is an upwardly open recess 1 1 having a cross-sectional shape complementary to the cross-sectional shape of a lower body member 31 of a measured dose dispenser which is a source of liquid to be dispensed and which will be described below. The lower body member 31 fits into recess 11 in slidable relationshiptherewith. A further recess 12 is provided in the bottom of the recess 11 which has a cross-sectional shape complementary to the cross-sectional shape of the hollow stem portion 37 of the measured dose dispenser and which receives the hollow stem portion 37 in a substantially fluid tight fit with the end of the stem portion 37 in the bottom of the recess 12 and with the parts in the rest or non-dispensing positions as seen in FIG. 1, with the lower end of the lower body member 31 spaced above the bottom of the recess 11.
Nozzle means 13 in the form of a nozzle insert 14 opens out of the side of the dispensing body 10. The nozzle insert 14 is positioned in a laterally opening recess 16 in the dispenser body which is shaped to leave a an annular mixing chamber 17 around the nozzle insert. The nozzle insert has a Venturi passage 14a therethrough which has lateral passages 14b extending from the mixing chamber into the Venturi passage 14a. In the specific form of the structure as shown, the recess 16 has a smaller diameter portion at the inner end and a larger diameter portion at the outer end and the nozzle insert 14 has a smaller diameter portion which fits into the smaller diameter portion of the recess but is longerthan this portion is deep. The larger diameter portion of the nozzle insert is thus spaced outwardly of the bottom of the larger portion of recess 16 to leave the mixing chamber 17. The dispenser body has a liquid product flow path therethrough in the form of a passage from the recess 12 to the mixing chamber 17 around the nozzle insert 14.
A source of gas under pressure in the form of an air compressing piston cylinder means is provided on the opposite end of the body 10 from the measured dose dispenser, and in the embodiment disclosed comprises a cylinder 18 which extends downwardly from the body 10 and within which a piston 19 is slidably positioned. Gasket 19a seals the piston in its movement into the cylinder 18. A return spring 20 within the cylinder 18 urges the piston 19 out of the cylinder 18. Opening out of the inner end of the cylinder 18 and into the body 10 is a recess 21, and from the recess 21 a compressed air path is provided which has a vertically extending portion 22 and one horizontal branch 23 extending to the central passage of the nozzle insert and a second horizontal branch 24 extending to the mixing chamber 17. The recess 21 and the air path portions comprise a compressed air flow path through the body 10. Within the recess 21 is a compressed air controlling poppet valve member 25 which seats on a seat 26 retained in the recess 21 by a retainer 27 which is positioned in the inner end of the cylinder 18. A valve return spring 28 in the recess 21 holds the poppet valve on the seat 26. An actuating pin 29 extends upwardly from the piston 19. At the inner end of the stroke of the piston 19, it is engaged with the poppet valve member 25 to lift the poppet valve member 25 from the seat 26 sufficiently far to pass compressed air into the recess 21.
The measured dose dispenser in this embodiment is in a form in which it is a source of pressurized liquid. It comprises a piston-cylinder means generally indicated at 30 in which the lower body member 31 is in the form of a piston over which a cylinder 32 is slidable. A gasket 32a in the end of the lower body member 31 seals against the inside surface of the cylinder 32 as the cylinder slides along the piston. The lower body member, 31 is made up of an outer shell 33 within which is positioned an inner body 34. The end of the shell 33 has an aperture 33a therein and on the inside of the shell between the bottom thereof and the end of the inner body 34 is a first annular sealing gasket 35. The inner body 34 has a larger diameter recess 34a in the end toward the bottom of the shell, and has a smaller diameter bore 34b extending from the inner end of the recess 34a to the end of the lower body member which is within the cylinder 32.
Movably mounted within the recess 34a and bore 34b is a metering valve stem generally indicated at 36 which has a solid stem portion within the recess 34a and has the hollow stern portion 37 extending from the solid stem portion out through the first annular sealing gasket 35 and the apertures 33a in the bottom of the shell 33, the outside surface of the hollow stem portion 37 being in sealing relationship with the first annular sealing gasket 35. At the joint between the hollow stem portion 37 and the solid stem portion is a flange 38 which in the rest position of the stem, as shown in FIG. 1, rests on the first annular gasket 35. The cross-sectional shape of the solid stem portion is such that it will move freely into the bore 34b. Around the end of the bore 34b where it opens into the larger diameter recess 34a is a second annular sealing gasket 40 through which the solid portions of the stem can move in sealing relationship therewith when the stem 36 is raised. A spring 39 is positioned between the second annular sealing gasket 40 and the flange 38, and urges the flange toward the first annular sealing gasket 35.
In the hollow stem portion 37 is an aperture 37b which in the rest position of the device as shown in FIG. 1 is below or outside the bottom of the lower body member 31. In the dispensing position this aperture is within the larger diameter recess 34a.
It will be seen that the valve stem 36 and the inner body 34 with its larger diameter recess 34a, the annular sealing gaskets 35 and 40, and the spring 39 form a simple metering stem which is known from the aerosol dispensing art and is shown in US. Pat. no. 2,721,010.
In operation, with the parts in the positions as shown in FIG. 1 and with the cylinder filled with the liquid L, pressure is exerted against the top of the cylinder 32 to urge the cylinder along the lower body member 31 to thereby exert pressure on the liquid L within the cylinder and within the smaller diameter bore 34b and larger diameter recess 340. Since the stem 36 is fixed in position in recess 12, the pressure will move the lower body member 31 down around the stem 36 against the action of the spring 39, first causing the second annular sealing gasket 40 to move around the upper end of the solid portion of the stem 36 and seal off the recess 34a from the smaller diameter bore 34b and the interior of the cylinder 32 thus trapping a metered quantity of liquid in recess 34a. Thereafter, further movement of the lower body member 31 and cylinder 32 downwardly along the stem 36 causes the first annular sealing gasket 35 to move past the aperture 37b so that the recess 34a is in communication with the interior of the hollow stem portion 37.
It has been found that with this construction, when the aperture 37b is placed in communication with the recess 34a, the liquid which has been trapped in the recess 34a is ejected from the hollow stem portion 37 in a squirt which has considerable force.
In the operation of the overall device when pressure is exerted by the fingers of the user on the cylinder 32 of the measured dose dispenser and the piston 19 of the air compressing piston cylinder means, the measured dose dispenser is caused to operate to dispense a squirt of liquid through the hollow stem portion 37 into the product flow path 15 and into the mixing chamber 17. At the same time, air is compressed in the cylinder 18, ahead of the piston 19. However, until the piston 19 reaches the end of its stroke, the poppet valve 25 remains closed. When the actuating pin 29 hits the poppet valve 25, the poppet valve is lifted from the seat 26, as shown in FIG. 2, and the air compressed in the cylinder 18 is suddenly released to flow through the compressed air path both to the mixing chamber 17 around the nozzle insert 14 and through the central Venturi passage of the nozzle insert. The compressed air flowing into the mixing chamber 17 mixes with and exerts a shearing effect on the liquid under pressure from the metered dose dispenser so as to break up the liquid, and this mixture is drawn through the lateral passages 18 into the stream of gas under pressure which is flowing through the center of the nozzle insert. The liquid is subjected to further break up in the Venturi passage and is immediately dispensed from the nozzle insert as a fine spray of dropletsof the liquid in compressed air without there first being ejected relatively large droplets of liquid.
A particular advantage of such a source of pressurized liquid as described above is that it can be simply replaced by a filled measured dose dispensing device. In addition to dispensing only a measured dose, the valve means of the measured dose dispenser acts to control the flow of the liquid product from the liquid supply in a simple and effective manner and independently of the air valve controlling the flow of the compressed air from the air compressing piston cylinder means.
While the metered dose dispensing device has been shown as one specific source of pressurized liquid, other sources can also be provided, such as are disclosed in the above mentioned copending application Ser. No. 496,282. Moreover, while the piston-cylinder air pressurizing means have been described as a specific source of gas under pressure, other sources could be provided, for example a valved conventional aerosol can containing a conventional propellant under pressure.
The source of liquid can be a source which does not supply liquid under pressure, i.e., can be a source which simply presents to the system the source of liquid so that the liquid is aspirated by the reduced pressure in the system caused by the compressed air flowing through the Venturi passage in the nozzle 14. One embodiment of such a source of liquid is shown in FIG. 4, which shows the structure thereof and only a part of the structure of the remainder of the device. As seen in FIG. 4 the source of liquid 41 has an outer casing '43 which fits into the recess 1 1 in the dispenser body in the same manner as does the source 30. Over the upper end of the casing 43 is a cover 430. Wlthin the casing 43 is an inner body 44. The end of the casing 43 has an aperture 43a therein and on the inside of the casing between the bottom thereof and the end of the inner body 44 is a first annular sealing gasket 45. The inner body 44 has a larger diameter recess 44a in the end toward the bottom of the casing 43 and has a smaller diameter bore 44b extending from the inner end of the recess 44a to the end of the inner body 44 which is within the upper part of the casing 43. A nipple 44c projects upwardly from the end of the smaller diameter bore 44b.
Movably mounted within the recess 44a and bore 44b is a metering valve stem generally indicated at 46 which has a solid stem portion within the recess 44a and has a hollow stem portion 47 extending from the solid stem portion out through the first annular sealing gasket 45 and the aperture 43a in the bottom of the casing 43, the outside surface of the hollow stemportion 47 being in sealing relationship with the first annular sealing gasket 45. At the joint between the hollow stem portion 47 and the solid stem portion is a flange 48, which in the rest position of the stem, as shown in FIG. 4, rests on the first annular gasket 45. The cross-sectional shape of the solid stem portion is such that it will move freely into the bore 44b. Around the end of the bore 44b where it opens intothe larger diameter recess 44a is a second annular sealing gasket 50 through which'the solid portion of the stern can move in sealing relationship therewith when the .stem 46 is raised. A spring 49 is positioned between the second annular sealing gasket 50 and the flange 48, and urges the flange toward the first annular sealing gasket 45.-
In the hollow stem portion 47 is an aperture 4712 which in the rest position of the device as shown in FIG. 4 is below or outside the bottom of the casing 43. In the dispensing position this aperture is within the larger diameter recess 44a.
It will be seen that the valve stem 46 and the inner body 44 with its larger diameter recess 44a, the annular sealing gaskets 45 and 50, and the spring 49 form a simple metering stem which is known from the aerosol dispensing art and is shown in US. Pat. No. 2,72l,010
A flexible bag 51 filled with liguid L, is positioned within the upper end of casing 43 with the mouth in liquid tight engagement with the nipple 440. An aperture or vent 43d is provided in casing 43 opening into the space containing the bag.
In operation, with the parts in the positions as shown in FIG. 4 and with the bag 51 filled with liquid L, pressure is exerted against the cover 430. Since the stem 46 is fixed in position in recess 12, the pressure will move the casing 43 down around the stem 46 against the action of the spring 49, first causing the second annular sealing gasket 50 to move around the upper end of the solid portion of the stem 46 and seal off the recess 44a from the smaller diameter bore 44b and the interior of the bag 51 thus trapping a metered quantity of liquid in recess 44a. Thereafter, further movement of the casing 43 downwardly along the stem 46 causes the first annular sealing gasket 45 to move past the aperture 47b so that the recess 44a is in communication with the inte rior of the hollow stem portion 47. When the aperture 47b is placed in communication with the recess 440, the liquid which has been trapped in the recess 44a is free to flow through the hollow stem portion 47.
In the operation of the overall device when pressure is exerted by the fingers of the user on the cover 43c of the measured dose dispenser and the piston 19 of the air compressing piston cylinder means, the measured dose dispenser exposes a measured amount of liquid through the hollow stem portion 47, the product flow path 15 and the mixing chamber 17. At the same time, air is compressed in the cylinder 18, ahead of the piston 19. However, until the piston 19 reaches the end of its stroke, the poppet valve 25 remains closed. When the actuating pin 29 hits the poppet valve 25, the poppet valve is lifted from the seat 26, as shown in FIG. 2, and the air compressed in the cylinder 18 is suddenly released to flow through the compressed air path both to the mixing chamber 17 around the nozzle insert 14 and through the central Venturi passage of the nozzle insert. Compressed air flowing through the Venturi passage 14a aspirates the measured amount of liquid from the source 41 and draws it into the mixing chamber 17. The compressed air flowing into the supply chamber 17 mixes with and exerts a shearing effect on the liquid from the metered dose dispenser so as to break up the liquid, and this mixture is drawn through the lateral openings 18 into the stream of gas under pressure which is flowing through the center of the nozzle insert. The liquid is subjected to further break up in the Venturi passage and is immediately dispensed from the nozzle insert as a fine spray of droplets of the liquid in compressed air without there first being ejected relatively large droplets of liquid.
The source of liquid as described above can also be resupplied simply be replacing the throwaway measured dose dispensing device. In addition to dispensing only a measured dose, the valve means of the measured dose dispenser acts to control the flow of the liquid product from the liquid supply in a simple and effective manner and independently of the air valve controlling the flow of the compressed air from the air compressing piston cylinder means, and also blocks flow of compressed air back into the bag 51.
When pressure or the source of liquid is released the parts return to the positions of FIG. 4, and air pressure on the bag 51 from vent 43d forces liquid into the recesses 44a and 44b.
lt will thus be seen that by a very simple change in the structure such that the gas under pressure and the liquid to be dispensed are supplied together to the supply chamber around the nozzle, and the gas under pressure is supplied to the central passage of the nozzle, the liquid is initially dispensed in the form of fine droplets, and the problem of spitting is overcome.
It is thought that the invention and its advantages will be understood from the foregoing description and it is apparent that various changes may be made in the form, construction and arrangement of the parts without departing from the spirit and scope of the invention or sacrificing its material advantages, the form hereinbefore described and illustrated in the drawings being merely a preferred embodiment thereof.
What is claimed is:
l. A device for dispensing a spray of the fine droplets of liquid in gas, comprising a dispenser body, said dispenser body having a nozzle means opening out of said body and having a central Venturi passage therethrough and lateral passages opening into said Venturi passage, said dispenser body having an annular mixing chamber around said central passage to which said lateral passages are connected, a source of liquid to be dispensed having means for mechanically pressurizing said liquid and operatively associated with said dispenser body valve means controlling dispensing of liquid from said source; said dispenser body having a product flow conduit therethroug from said valve means for said source of liquid to said annular mixing chamber and a source of gas under pressure and opening axially into the central Venturi passage of said nozzle means, and a branch compressed gas flow conduit branching from said main compressed gas flow conduit and opening into said annular mixing chamber at a point spaced from the point at which said product flow conduit opens into said annular mixing chamber.
2. A device as claimed in claim 1 in which said source of liquid comprises a measured dose dispenser having a piston-cylinder means containing the liquid to be dispensed, and said valve means is a measured dose dispensing valve means for dispensing a measured dose of the liquid when the piston-cylinder means is actuated.
3. A device as claimed in claim 1 in which said source of compressed gas comprises an air compressing piston-cylinder means having a fixed member and a movable member movable through a compressing stroke, relative to the fixed member and a compressed air controlling valve member in said compressed air flow path normally closing said path, actuating pin means operatively associated with said air compressing piston-cylinder means and said compressed air controlling valve member for actuating said compressed air valve member to open it near the end of the compression stroke.
4. A device as claimed in claim 3 in which said source of liquid comprises a dispenser having a liquid pressurizing piston-cylinder means containing the liquid to be dispensed, and said valve means is a measured dose dispensing valve means for dispensing an amount of the liquid when the liquid pressurizing piston-cylinder means is actuated, said air compressing piston-cylinder means being on one end of said dispenser body and the liquid pressurizing piston-cylinder means being on the other end of said dispenser body, whereby pressure on the opposite ends of said device actuates both pistoncylinder means.
5. A device as claimed in claim 1 in which said source of liquid is a source of unpressurized liquid and comprises a measured dose dispenser having a container for the liquid which is at atmospheric pressure, and said valve means is a measured dose dispensing valve means for permitting aspiration of a measured dose of the liquid when said valve means is actuated.

Claims (5)

1. A device for dispensing a spray of the fine droplets of liquid in gas, comprising a dispenser body, said dispenser body having a nozzle means opening out of said body and having a central Venturi passage therethrough and lateral passages opening into said Venturi passage, said dispenser body having an annular mixing chamber around said central passage to which said lateral passages are connected, a source of liquid to be dispensed having means for mechanically pressurizing said liquid and operatively associated with said dispenser body valve means controlling dispensing of liquid from said source; said dispenser body having a product flow conduit therethroug from said valve means for said source of liquid to said annular mixing chamber and a source of gas under pressure and opening axially into the central Venturi passage of said nozzle means, and a branch compressed gas flow conduit branching from said main compressed gas flow conduit and opening into said annular mixing chamber at a point spaced from the point at which said product flow conduit opens into said annular mixing chamber.
2. A device as claimed in claim 1 in which said source of liquid comprises a measured dose dispenser having a piston-cylinder means containing the liquid to be dispensed, and said valve means is a measured dose dispensing valve means for dispensing a measured dose of the liquid when the piston-cylinder means is actuated.
3. A device as claimed in claim 1 in which said source of compressed gas comprises an air compressing piston-cylinder means having a fixed member and a movable member movable through a compressing stroke, relative to the fixed member and a compressed air controlling valve member in said compressed air flow path normally closing said path, actuating pin means operatively associated with said air compressing piston-cylinder means and said compressed air controlling valve member for actuating said compressed air valve member to open it near the end of the compression stroke.
4. A device as claimed in claim 3 in which said source of liquid comprises a dispenser having a liquid pressurizing piston-cylinder means containing the liquid to be dispensed, and said valve means is a measured dose dispensing valve means for dispensing an amount of the liquid when the liquid pressurizing piston-cylinder means is actuated, said air compressing piston-cylinder means being on one end of said dispenser body and the liquid pressurizing piston-cylinder means being on the other end of said dispenser body, whereby pressure on the opposite ends of said device actuates both piston-cylinder means.
5. A device as claimed in claim 1 in which said source of liquid is a source of unpressurized liquid and comprises a measured dose dispenser having a container for the liquid which is at atmospheric pressure, and said valve means is a measured dose dispensing valve means for permitting aspiration of a measured dose of the liquid when said valve means is actuated.
US419966A 1973-10-31 1973-11-29 Non-spitting liquid dispensing device Expired - Lifetime US3921857A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
US419966A US3921857A (en) 1973-11-29 1973-11-29 Non-spitting liquid dispensing device
CH1430574A CH588896A5 (en) 1973-10-31 1974-10-25
NL7414127A NL7414127A (en) 1973-10-31 1974-10-29 AEROROL SPRAYER.
AR25632174A AR210252A1 (en) 1973-10-31 1974-10-29 AEROSOL DISPENSER USED AS A MANUAL SPRAYING DEVICE
DE19742451367 DE2451367C3 (en) 1973-10-31 1974-10-29 Aerosol atomizer designed as a hand spray can
FR7436146A FR2257352B1 (en) 1973-10-31 1974-10-29
DE19742462461 DE2462461A1 (en) 1973-10-31 1974-10-29 AEROSOL SPRAYER TRAINED AS A HAND SPRAY CAN
SE7413599A SE7413599L (en) 1973-10-31 1974-10-29
IT5380974A IT1032113B (en) 1973-10-31 1974-10-30 Aerosol spray can - has propellant pressure applied to fluid reservoir upstream of adjustable control valve
CA212,645A CA1008033A (en) 1973-10-31 1974-10-30 Aerosol dispenser and novel nozzle arrangements therefor
AU74866/74A AU495580B2 (en) 1974-10-30 Pressurised aerosol dispenser
DK566374A DK142132B (en) 1973-10-31 1974-10-30 Aerosol nebulizer with manually operated atomisers.
BE150044A BE821667A (en) 1973-10-31 1974-10-30 AEROSOL DISPENSER WITH A NEW NOZZLE ARRANGEMENT
GB2872577A GB1493615A (en) 1973-10-31 1974-10-31 Aerosol dispensers
GB4718174A GB1493614A (en) 1973-10-31 1974-10-31 Aerosol dispensers
JP12498774A JPS5078912A (en) 1973-10-31 1974-10-31

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US419966A US3921857A (en) 1973-11-29 1973-11-29 Non-spitting liquid dispensing device

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US3921857A true US3921857A (en) 1975-11-25

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CN108636646A (en) * 2018-05-15 2018-10-12 北京空间飞行器总体设计部 It is a kind of can multi-injection integral type fluidic device and jetting method
CN108672119A (en) * 2018-07-04 2018-10-19 浙江精勇精锻机械有限公司 Releasing agent automatic spray apparatus
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US5497944A (en) * 1990-03-21 1996-03-12 Dmw (Technology) Limited Atomising devices and methods
US5662271A (en) * 1990-03-21 1997-09-02 Boehringer Ingelheim International Gmbh Atomizing devices and methods
US5405084A (en) * 1990-12-04 1995-04-11 Dmw (Technology) Limited Nozzle assembly for preventing back-flow
US5402943A (en) * 1990-12-04 1995-04-04 Dmw (Technology) Limited Method of atomizing including inducing a secondary flow
US20050029296A1 (en) * 2002-09-13 2005-02-10 Bissell Homecare, Inc. Aerosol package
US7021499B2 (en) * 2002-09-13 2006-04-04 Bissell Homecare, Inc. Aerosol package
US20100264168A1 (en) * 2009-03-10 2010-10-21 Eric Stephen Larabee Liquid dispensing device
US8727181B2 (en) * 2009-03-10 2014-05-20 Eric Stephen Larabee Liquid dispensing device
US9168548B2 (en) 2009-03-10 2015-10-27 Eric Stephen Larabee Liquid dispensing device
US9889455B2 (en) * 2011-08-30 2018-02-13 Mccormick & Company, Incorporated Particulate sprayer
US20130056547A1 (en) * 2011-08-30 2013-03-07 Mccormick & Company, Incorporated Particulate sprayer
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US10010225B2 (en) * 2013-12-05 2018-07-03 Kokomo Limited Foam formulation and aerosol assembly
US20160302624A1 (en) * 2013-12-05 2016-10-20 Kokomo Limited Foam Formulation and Aerosal Assembly
US11266799B2 (en) * 2015-09-10 2022-03-08 Impel Neuropharma, Inc. In-line nasal delivery device
WO2017044897A1 (en) 2015-09-10 2017-03-16 Impel Neuropharma Inc. In-line nasal delivery device
CN108601916A (en) * 2015-09-10 2018-09-28 英倍尔药业股份有限公司 In-line nasal delivery device
IL257845B (en) * 2015-09-10 2022-07-01 Impel Neuropharma Inc In-line nasal delivery device
CN108601916B (en) * 2015-09-10 2021-07-09 英倍尔药业股份有限公司 In-line nasal delivery device
EP3341059A4 (en) * 2015-09-10 2019-05-08 Impel Neuropharma Inc. In-line nasal delivery device
JP7001777B2 (en) 2015-09-10 2022-02-10 インペル ニューロファーマ インコーポレイテッド Serial nasal delivery device
JP2020185475A (en) * 2015-09-10 2020-11-19 インペル ニューロファーマ インコーポレイテッド In-line nasal delivery device
AU2016321345B2 (en) * 2015-09-10 2020-12-10 Impel Pharmaceuticals Inc. In-line nasal delivery device
FR3046553A1 (en) * 2016-01-07 2017-07-14 Aptar France Sas NASAL DISTRIBUTION SET OF FLUID PRODUCT.
US20190001088A1 (en) * 2016-01-07 2019-01-03 Aptar France Sas Nasal delivery assembly for a fluid product and method for actuating the assembly
WO2017118825A1 (en) 2016-01-07 2017-07-13 Aptar France Sas Nasal delivery assembly for a fluid product and method for actuating the assembly
CN111386137A (en) * 2017-09-26 2020-07-07 株式会社新日本科学 Intranasal delivery device
US11744967B2 (en) * 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
US12102754B2 (en) 2017-09-26 2024-10-01 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
US11185497B2 (en) 2018-01-05 2021-11-30 Impel Neuropharma, Inc. Intranasal delivery of dihydroergotamine by precision olfactory device
CN108636646B (en) * 2018-05-15 2019-12-20 北京空间飞行器总体设计部 Integrated jet device capable of jetting for multiple times and jet method
CN108636646A (en) * 2018-05-15 2018-10-12 北京空间飞行器总体设计部 It is a kind of can multi-injection integral type fluidic device and jetting method
CN108672119A (en) * 2018-07-04 2018-10-19 浙江精勇精锻机械有限公司 Releasing agent automatic spray apparatus
CN108672119B (en) * 2018-07-04 2024-02-13 浙江精勇精锻机械有限公司 Automatic spraying device for release agent

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