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US3905777A - Composite and porous metallic members which can be used for bone prosthesis - Google Patents

Composite and porous metallic members which can be used for bone prosthesis Download PDF

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Publication number
US3905777A
US3905777A US436850A US43685074A US3905777A US 3905777 A US3905777 A US 3905777A US 436850 A US436850 A US 436850A US 43685074 A US43685074 A US 43685074A US 3905777 A US3905777 A US 3905777A
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US
United States
Prior art keywords
covering
core
foil
member according
metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US436850A
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English (en)
Inventor
Roger Lacroix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Comptoir Lyon-Alemand Louyot and Cie
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Comptoir Lyon-Alemand Louyot and Cie
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/306Other specific inorganic materials not covered by A61L27/303 - A61L27/32
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B22CASTING; POWDER METALLURGY
    • B22FWORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F7/00Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression
    • B22F7/002Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression of porous nature
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
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    • Y10T428/12All metal or with adjacent metals
    • Y10T428/12014All metal or with adjacent metals having metal particles
    • Y10T428/12028Composite; i.e., plural, adjacent, spatially distinct metal components [e.g., layers, etc.]
    • Y10T428/12042Porous component
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/12All metal or with adjacent metals
    • Y10T428/12014All metal or with adjacent metals having metal particles
    • Y10T428/12028Composite; i.e., plural, adjacent, spatially distinct metal components [e.g., layers, etc.]
    • Y10T428/12063Nonparticulate metal component
    • Y10T428/12069Plural nonparticulate metal components
    • Y10T428/12076Next to each other
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/12All metal or with adjacent metals
    • Y10T428/12361All metal or with adjacent metals having aperture or cut
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/12All metal or with adjacent metals
    • Y10T428/12431Foil or filament smaller than 6 mils
    • Y10T428/12438Composite
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/12All metal or with adjacent metals
    • Y10T428/12444Embodying fibers interengaged or between layers [e.g., paper, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/12All metal or with adjacent metals
    • Y10T428/12493Composite; i.e., plural, adjacent, spatially distinct metal components [e.g., layers, joint, etc.]
    • Y10T428/12771Transition metal-base component
    • Y10T428/12806Refractory [Group IVB, VB, or VIB] metal-base component
    • Y10T428/12812Diverse refractory group metal-base components: alternative to or next to each other

Definitions

  • a method is also described which involves dipping the member into a suspension of the hydride of the member of the core and subsequently heating the core at high temperature.
  • the porous body or the porous layer is formed by small discrete particles of metal welded together and for a proportion of them to the substrate or core. These welded connections only occupy limited space so that between the particles free spaces are left which provide the desired porosity. These particles may be cylindrical or spherical.
  • the contact between the spherical or cy lindrical particles before the welding operation is reduced to a point or to a line. It is thus necessary that the operation of welding should itself give rise to the growth of a contact surface of larger size when filaments or atomized powders are sued.
  • This welding can only be effected by roasting, that is to say, by thermal treatment at elevated temperature, about 1200C in the case of Vitallium, 1100C in the case of titanium. At these temperatures diffusion phenomena in the solid phase give rise to the joining of the elements in contact by the growth of joining surfaces from the contact points. These phenomenon are slow and growth of the contact areas slows up when the connecting or joining surfaces increase.
  • the invention relates also to another type of 'improved implant characterized inthat the external surface of the-porous coveringof an implant carriesfine particles of the same.metal as the implant, of a diameter less than microns and welded to this surface.
  • an implant l is illustrated formed from a core 2 and a porous covering 3 constituted by metallic foils 4 of a light gauge and which are superposed on one another.
  • the bone 5 grows into the pores of this porous covering 3.
  • the implant is subjected to shear forces F and to tension forces F,.
  • the prosthesis After drying the prosthesis is treated in a vacuum of l5 l0 mm at l.lC.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Composite Materials (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
US436850A 1973-01-31 1974-01-28 Composite and porous metallic members which can be used for bone prosthesis Expired - Lifetime US3905777A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7303415A FR2215927B1 (ja) 1973-01-31 1973-01-31

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US3905777A true US3905777A (en) 1975-09-16

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US436850A Expired - Lifetime US3905777A (en) 1973-01-31 1974-01-28 Composite and porous metallic members which can be used for bone prosthesis

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US (1) US3905777A (ja)
CH (1) CH575753A5 (ja)
DE (1) DE2404214C3 (ja)
FR (1) FR2215927B1 (ja)
GB (1) GB1465501A (ja)

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WO1984000185A1 (en) * 1982-06-28 1984-01-19 Dow Chemical Co Expanded mesh of grade 2 titanium
US4553272A (en) * 1981-02-26 1985-11-19 University Of Pittsburgh Regeneration of living tissues by growth of isolated cells in porous implant and product thereof
US4612160A (en) * 1984-04-02 1986-09-16 Dynamet, Inc. Porous metal coating process and mold therefor
US4644942A (en) * 1981-07-27 1987-02-24 Battelle Development Corporation Production of porous coating on a prosthesis
US4650489A (en) * 1986-01-30 1987-03-17 Massachusetts Institute Of Technology Prosthetic device for implantation in bone
US4660755A (en) * 1985-09-09 1987-04-28 Zimmer, Inc. Method for constructing a surgical implant
US4829152A (en) * 1987-11-16 1989-05-09 Rostoker, Inc. Method of resistance welding a porous body to a substrate
US4957819A (en) * 1988-06-10 1990-09-18 Haruyuki Kawahara Frameless and coreless porous endosseous implant
US5080671A (en) * 1987-11-25 1992-01-14 Uri Oron Method of treating a metal prosthetic device prior to surgical implantation to enhance bone growth relative thereto following implantation
US5108435A (en) * 1989-09-28 1992-04-28 Pfizer Hospital Products Group, Inc. Cast bone ingrowth surface
US5108432A (en) * 1990-06-24 1992-04-28 Pfizer Hospital Products Group, Inc. Porous fixation surface
US5196016A (en) * 1991-03-11 1993-03-23 Institut Straumann Ag Auxiliary means and method for fastening a capping on bone tissue or the like
US5219363A (en) * 1988-03-22 1993-06-15 Zimmer, Inc. Bone implant
US5330700A (en) * 1990-04-10 1994-07-19 Siemens Pacesetter, Inc. Porous electrode for a pacemaker and method of making same
US5360448A (en) * 1991-10-07 1994-11-01 Thramann Jeffrey J Porous-coated bone screw for securing prosthesis
US5387243A (en) * 1992-11-23 1995-02-07 Zimmer, Inc. Method for converting a cementable implant to a press fit implant
US5443512A (en) * 1990-10-30 1995-08-22 Zimmer, Inc. Orthopaedic implant device
US5672284A (en) * 1994-04-18 1997-09-30 Zimmer, Inc. Method of making orthopaedic implant by welding
US5713901A (en) * 1993-07-30 1998-02-03 Tock; Gideon Raphael Reticulated orthopaedic element to exploit the medullary canal of the long bones
US5733284A (en) * 1993-08-27 1998-03-31 Paulette Fairant Device for anchoring spinal instrumentation on a vertebra
US5755811A (en) * 1995-08-25 1998-05-26 Zimmer, Inc. Prosthetic implant with fins
US5843289A (en) * 1996-01-22 1998-12-01 Etex Corporation Surface modification of medical implants
US5973222A (en) * 1994-04-18 1999-10-26 Bristol-Myers Squibb Co. Orthopedic implant having a porous metal pad
US6033582A (en) * 1996-01-22 2000-03-07 Etex Corporation Surface modification of medical implants
US6077076A (en) * 1997-12-18 2000-06-20 Comfort Biomedical, Inc. Bone augmentation for prosthetic implants and the like
US6214049B1 (en) 1999-01-14 2001-04-10 Comfort Biomedical, Inc. Method and apparatus for augmentating osteointegration of prosthetic implant devices
EP1527757A1 (en) * 2003-11-03 2005-05-04 Finsbury (Development) Limited Prosthetic implant
WO2005094731A1 (en) 2004-03-31 2005-10-13 Scyon Orthopaedics Ag Double shell implant for cementless anchorage of joint prostheses
JP2005296450A (ja) * 2004-04-14 2005-10-27 Masahiko Chiba 生体用多孔質体の製造方法
US7208222B2 (en) 2003-07-24 2007-04-24 Viasys Healthcare Inc. Assembled non-random foams
US20090068339A1 (en) * 2007-09-06 2009-03-12 Boston Scientific Scimed, Inc. Endoprostheses having porous claddings prepared using metal hydrides
US7597715B2 (en) 2005-04-21 2009-10-06 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US7635447B2 (en) 2006-02-17 2009-12-22 Biomet Manufacturing Corp. Method and apparatus for forming porous metal implants
US20100211109A1 (en) * 2008-08-14 2010-08-19 Doerr Timothy E Tack for spine fixation
US20110106170A1 (en) * 2008-08-14 2011-05-05 Doerr Timothy E Tack for spine fixation
US8021432B2 (en) 2005-12-05 2011-09-20 Biomet Manufacturing Corp. Apparatus for use of porous implants
US8066778B2 (en) 2005-04-21 2011-11-29 Biomet Manufacturing Corp. Porous metal cup with cobalt bearing surface
US8123814B2 (en) 2001-02-23 2012-02-28 Biomet Manufacturing Corp. Method and appartus for acetabular reconstruction
US20120064290A1 (en) * 2008-12-01 2012-03-15 The Furlong Research Charitable Foundation Article and method of surface treatment of an article
US8266780B2 (en) 2005-04-21 2012-09-18 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8292967B2 (en) 2005-04-21 2012-10-23 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US20130180970A1 (en) * 2010-11-18 2013-07-18 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US20140151342A1 (en) * 2010-11-18 2014-06-05 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US20150289911A1 (en) * 2012-11-11 2015-10-15 Carbofix Orthopedics Ltd. Composite implant coating
US20160331539A1 (en) * 2015-05-12 2016-11-17 Elwha Llc Modifiable implants
US20180228616A1 (en) * 2017-02-10 2018-08-16 Zimmer, Inc. Additive manufactured femoral components
CN111481738A (zh) * 2020-03-25 2020-08-04 天衍医疗器材有限公司 一种生物活性多孔钽植入物制备方法

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Cited By (70)

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Publication number Priority date Publication date Assignee Title
US4553272A (en) * 1981-02-26 1985-11-19 University Of Pittsburgh Regeneration of living tissues by growth of isolated cells in porous implant and product thereof
US4644942A (en) * 1981-07-27 1987-02-24 Battelle Development Corporation Production of porous coating on a prosthesis
WO1984000185A1 (en) * 1982-06-28 1984-01-19 Dow Chemical Co Expanded mesh of grade 2 titanium
US4612160A (en) * 1984-04-02 1986-09-16 Dynamet, Inc. Porous metal coating process and mold therefor
US4660755A (en) * 1985-09-09 1987-04-28 Zimmer, Inc. Method for constructing a surgical implant
US4650489A (en) * 1986-01-30 1987-03-17 Massachusetts Institute Of Technology Prosthetic device for implantation in bone
US4829152A (en) * 1987-11-16 1989-05-09 Rostoker, Inc. Method of resistance welding a porous body to a substrate
US5080671A (en) * 1987-11-25 1992-01-14 Uri Oron Method of treating a metal prosthetic device prior to surgical implantation to enhance bone growth relative thereto following implantation
US5219363A (en) * 1988-03-22 1993-06-15 Zimmer, Inc. Bone implant
US4957819A (en) * 1988-06-10 1990-09-18 Haruyuki Kawahara Frameless and coreless porous endosseous implant
US5108435A (en) * 1989-09-28 1992-04-28 Pfizer Hospital Products Group, Inc. Cast bone ingrowth surface
US5330700A (en) * 1990-04-10 1994-07-19 Siemens Pacesetter, Inc. Porous electrode for a pacemaker and method of making same
US5108432A (en) * 1990-06-24 1992-04-28 Pfizer Hospital Products Group, Inc. Porous fixation surface
US5443512A (en) * 1990-10-30 1995-08-22 Zimmer, Inc. Orthopaedic implant device
US5196016A (en) * 1991-03-11 1993-03-23 Institut Straumann Ag Auxiliary means and method for fastening a capping on bone tissue or the like
US5360448A (en) * 1991-10-07 1994-11-01 Thramann Jeffrey J Porous-coated bone screw for securing prosthesis
US5387243A (en) * 1992-11-23 1995-02-07 Zimmer, Inc. Method for converting a cementable implant to a press fit implant
US5713901A (en) * 1993-07-30 1998-02-03 Tock; Gideon Raphael Reticulated orthopaedic element to exploit the medullary canal of the long bones
US5733284A (en) * 1993-08-27 1998-03-31 Paulette Fairant Device for anchoring spinal instrumentation on a vertebra
US5973222A (en) * 1994-04-18 1999-10-26 Bristol-Myers Squibb Co. Orthopedic implant having a porous metal pad
US5672284A (en) * 1994-04-18 1997-09-30 Zimmer, Inc. Method of making orthopaedic implant by welding
US5755811A (en) * 1995-08-25 1998-05-26 Zimmer, Inc. Prosthetic implant with fins
US6582470B1 (en) 1996-01-22 2003-06-24 Etex Corporation Surface modification of medical implants
US5843289A (en) * 1996-01-22 1998-12-01 Etex Corporation Surface modification of medical implants
US6033582A (en) * 1996-01-22 2000-03-07 Etex Corporation Surface modification of medical implants
US6464889B1 (en) 1996-01-22 2002-10-15 Etex Corporation Surface modification of medical implants
US6077076A (en) * 1997-12-18 2000-06-20 Comfort Biomedical, Inc. Bone augmentation for prosthetic implants and the like
US6143036A (en) * 1997-12-18 2000-11-07 Comfort Biomedical, Inc. Bone augmentation for prosthetic implants and the like
US6461385B1 (en) 1997-12-18 2002-10-08 Comfort Biomedical Inc. Method and apparatus for augmenting osteointegration of prosthetic implant devices
US6214049B1 (en) 1999-01-14 2001-04-10 Comfort Biomedical, Inc. Method and apparatus for augmentating osteointegration of prosthetic implant devices
US9375316B2 (en) 2001-02-23 2016-06-28 Biomet Manufacturing, Llc. Method and apparatus for acetabular reconstruction
US8551181B2 (en) 2001-02-23 2013-10-08 Biomet Manufacturing, Llc Method and apparatus for acetabular reconstruction
US8123814B2 (en) 2001-02-23 2012-02-28 Biomet Manufacturing Corp. Method and appartus for acetabular reconstruction
US7208222B2 (en) 2003-07-24 2007-04-24 Viasys Healthcare Inc. Assembled non-random foams
EP1527757A1 (en) * 2003-11-03 2005-05-04 Finsbury (Development) Limited Prosthetic implant
US20050119759A1 (en) * 2003-11-03 2005-06-02 Finsbury (Development) Limited Prosthetic implant
US7497876B2 (en) 2003-11-03 2009-03-03 Finsbury (Development) Limited Prosthetic implant
US20070208428A1 (en) * 2004-03-31 2007-09-06 Scyon Orthopaedics Ag Double Shell Implant for Cementless Anchorage of Joint Prostheses
US7776097B2 (en) 2004-03-31 2010-08-17 Scyon Orthopaedics Ag Double shell implant for cementless anchorage of joint prostheses
WO2005094731A1 (en) 2004-03-31 2005-10-13 Scyon Orthopaedics Ag Double shell implant for cementless anchorage of joint prostheses
JP4524776B2 (ja) * 2004-04-14 2010-08-18 晶彦 千葉 生体用多孔質体の製造方法
JP2005296450A (ja) * 2004-04-14 2005-10-27 Masahiko Chiba 生体用多孔質体の製造方法
US8292967B2 (en) 2005-04-21 2012-10-23 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8266780B2 (en) 2005-04-21 2012-09-18 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US7597715B2 (en) 2005-04-21 2009-10-06 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8197550B2 (en) 2005-04-21 2012-06-12 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8066778B2 (en) 2005-04-21 2011-11-29 Biomet Manufacturing Corp. Porous metal cup with cobalt bearing surface
US8021432B2 (en) 2005-12-05 2011-09-20 Biomet Manufacturing Corp. Apparatus for use of porous implants
US7635447B2 (en) 2006-02-17 2009-12-22 Biomet Manufacturing Corp. Method and apparatus for forming porous metal implants
US7883736B2 (en) 2007-09-06 2011-02-08 Boston Scientific Scimed, Inc. Endoprostheses having porous claddings prepared using metal hydrides
US20090068339A1 (en) * 2007-09-06 2009-03-12 Boston Scientific Scimed, Inc. Endoprostheses having porous claddings prepared using metal hydrides
WO2009032475A2 (en) 2007-09-06 2009-03-12 Boston Scientific Limited Endoprostheses having porous claddings prepared using metal hydrides
WO2009032475A3 (en) * 2007-09-06 2009-08-13 Boston Scient Ltd Endoprostheses having porous claddings prepared using metal hydrides
US20110106170A1 (en) * 2008-08-14 2011-05-05 Doerr Timothy E Tack for spine fixation
US20100211109A1 (en) * 2008-08-14 2010-08-19 Doerr Timothy E Tack for spine fixation
US20120064290A1 (en) * 2008-12-01 2012-03-15 The Furlong Research Charitable Foundation Article and method of surface treatment of an article
US9044528B2 (en) * 2008-12-01 2015-06-02 Ucl Business Plc Article and method of surface treatment of an article
US20130180970A1 (en) * 2010-11-18 2013-07-18 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US9174297B2 (en) 2010-11-18 2015-11-03 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US20140151342A1 (en) * 2010-11-18 2014-06-05 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US10427235B2 (en) * 2010-11-18 2019-10-01 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US10537961B2 (en) * 2010-11-18 2020-01-21 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US11440118B2 (en) 2010-11-18 2022-09-13 Zimmer, Inc. Resistance welding a porous metal layer to a metal substrate
US20150289911A1 (en) * 2012-11-11 2015-10-15 Carbofix Orthopedics Ltd. Composite implant coating
US10045798B2 (en) * 2012-11-11 2018-08-14 Carbofix Orthopedics Ltd. Composite implant coating
US10687864B2 (en) * 2012-11-11 2020-06-23 Carbofix In Orthopedics Llc Composite implant coating
US20160331539A1 (en) * 2015-05-12 2016-11-17 Elwha Llc Modifiable implants
US20180228616A1 (en) * 2017-02-10 2018-08-16 Zimmer, Inc. Additive manufactured femoral components
US11259932B2 (en) * 2017-02-10 2022-03-01 Zimmer, Inc. Additive manufactured femoral components
CN111481738A (zh) * 2020-03-25 2020-08-04 天衍医疗器材有限公司 一种生物活性多孔钽植入物制备方法

Also Published As

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DE2404214A1 (de) 1974-08-01
GB1465501A (en) 1977-02-23
DE2404214B2 (de) 1977-11-24
FR2215927A1 (ja) 1974-08-30
FR2215927B1 (ja) 1976-05-14
DE2404214C3 (de) 1978-08-24
CH575753A5 (ja) 1976-05-31

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