US3870042A - Apparatus for separating and injecting blood component - Google Patents
Apparatus for separating and injecting blood component Download PDFInfo
- Publication number
- US3870042A US3870042A US295687A US29568772A US3870042A US 3870042 A US3870042 A US 3870042A US 295687 A US295687 A US 295687A US 29568772 A US29568772 A US 29568772A US 3870042 A US3870042 A US 3870042A
- Authority
- US
- United States
- Prior art keywords
- storage pocket
- blood
- component
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/221—Frangible or pierceable closures within tubing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0445—Proteins
- A61M2202/0447—Glycoproteins
- A61M2202/0454—Fibrinase, i.e. Factor XIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
Definitions
- the element thus separated and intended to be injected into a patient is taken from this storage pocket by means of a hollow needle which is used to pierce the pocket.
- a hollow needle which is used to pierce the pocket.
- the device just described has disadvantages, since the agglomerated particles may obstruct the passage in the hollow needle or may enter the patients vein and create circulation problems. Incidents of this kind generally occur where the blood component has been separated by cryoprecipitation, since agglomerated elements still remain after thawing. In order to avoid such incidents, it is usual to dilute the component in a solution, especially an isotonic solution, before injecting it into the patient. This operation is usually carried out in an adjacent pocket into which the constituent taken is introduced by means of the hollow needle.
- the component is transferred in a sterile manner to a storage pocket connected to the system of blood-taking and decanting pockets, the pocket comprising an internal filter and having dimensions corresponding to the amount of component isolated;
- the storage pocket is separated from the system of blood-taking and decanting pockets, and
- the component is kept in the storage pocket until it is injected into the patients vein.
- the component just isolated is transferred to the storage pocket, it is mixed with a rinsing solution, especially an isotonic solution, which dilutes, in part, the agglomerated elements; this rinsing solution is contained in a pocket connected in a sealed and sterile manner to the system of blood-taking and decanting pockets.
- a rinsing solution especially an isotonic solution, which dilutes, in part, the agglomerated elements
- the apparatus made in accordance with the present invention consists of a storage pocket containing a filter and having dimensions corresponding to the quantity of component isolated.
- the arrangement of the filter within the storage pocket is essential, since it produces adevice which is particularly compact and easy to use, in which dead volumes are greatly limited. This is essential if the quantities of component extracted from the blood are very small.
- the storage pocket also comprises injection means adapted to the end of the filter.
- injection means adapted to the end of the filter. The purpose of this arrangement is to avoid contamination of the components in the storage pocket at the time of their injection, but this highly compact arrangement of the injection means also helps to greatly limit dead volumes.
- the isotonic solution is kept, prior to use, in the storage pocket.
- the storage pocket which comprises a filter and injection means, contains a solution of the blood component already diluted and ready to be injected.
- FIG. 1 shows a side elevational view of the device according to the invention
- FIG. 2 shows a side elevational view of the storage pocket, partly broken away and to an enlarged scale
- FIG. 3 shows a side elevational view of another embodiment of the device according to the invention.
- FIG. I Illustrated in FIG. I is a device which comprises a first flexible pocket 1 made of transparent synthetic material. Opening into this pocket is the end of a flexible tube 3 made of weldable synthetic material, the other end thereof being integral with a hollow needle 4 protected by a sleeve 5.
- Pocket 10 Opening into pocket 1 is one end of a tube 8 made of weldable synthetic material, the other end of which is integral with one arm of a three-way union 9, the other two arms of which are connected respectively, through tubes 11 and 12, to flexible pockets 6 and 10.
- Pocket 10 is connected through a tube 13 to a storage pocket 14 made of two sheets of synthetic material welded together by their edges.
- Pocket 14 contains a filter 17 and injection means consisting, more particularly, of a tube 23 comprising an injection needle 15 protected by a cap 16.
- Filter 17 seen in FIG. 2, consists of a piece of fabric in the form of a sleeve, one end thereof being held by the weld at the bottom of the pocket, while the other end accommodates a ferrule 18 to which it is attached by the weld joining together the two sheets of which the pocket is made.
- ferrule 18 has an internal wall 19 intended to be pierced by a hollow needle 20 integral with a sleeve 21 connected to the injection needle by means of a tube 23.
- FIGS. 1 and 2 A description will now be given of the method of using the device illustrated in FIGS. 1 and 2.
- Hollow needle 4 is inserted into the patients vein. After the blood has been collected in pocket 1, tube 3 is flattened in the vicinity of the pocket and its walls are welded together in order to close it off. The remainder of the tube, which is no longer in use, is then cut off.
- tube 8 After tube 8 has been closed off, the element of the blood to be separated is decanted, through tubes 11 and '12, into pocket which contains an isotonic solution to be mixed with the element. This mixture is then transferred to pocket 14 through tube 13.
- element such as factor VIII
- Another way of using the present device consistsin passing the plasma contained in pocket 1 through tubes 8 and 12 into pocket 10, tube 11 being closed off, for example by means of a clamp.
- the component contained in the plasma (more particularly factor VIII which is used against haemophilia) is separated by cryo-precipitation in pocket 10.
- the unprecipitated fraction of the plasma is transferred to pocket 6 through tubes 11 and 12, after tube 8 has been closed off, for example with a clamp.
- the isotonic solution which in this configuration of the invention, is contained in storage pocket 14, is transferred to pocket 10 where it is used to dilute the component separated by cryo-precipitation. Pocket 10 is carefully rinsed with this solution, and the mixture of isotonic solution and component is transferred to pocket 14 through tube 13.
- Tube 13 is then flattened and welded and pocket 14 is then separated from pocket 10 by cutting the tube.
- the blood elements in pockets 1 and 6 are then retained for specific purposes, while the component in pocket 14 may be kept therein until it is-required for use.
- sleeve 21 is pushed into ferrule 18 in a manner such that needle 20 pierces wall 19, after which needle 15 is inserted into the patients veinand the component in its isotonic solution is injected directly by rolling up pocket 14 in order to force the liquid through tube 23.
- the agglomerated elements cannot pass through filter 17 and they therefore remain in pocket 14.
- Dead volumes are limited to a minimum since pocket 14 is small in size and the useful volume thereof corresponds substantially to the volume of component placed in solution for injection into the patient; moreover, the filtermeans is integrated into the storage pocket.
- a device of this kind also prevents contamination and ensures storage and injection under completely sterile conditions.
- FIG. 3 shows blood-taking pocket 1 with its means for taking blood, namely hollow needle 4 protected by cap 5.
- This pocket is connected, through tube 32, to a second pocket 30 which is connected in turn, through a tube 33, to a third pocket 31 and, through a tube 34, to a storage pocket 14.
- This latter pocket comprises a filter 17 integral with a ferrule 18 as described in connection with FIG. 2, the ferrule being integral with a sterile access port 35, and the end of the ferrule being adaptable to the injection means.
- the blood taken from the subjects vein is subjected to initial fractionation in pocket 1, more particularly by .centrifuging.
- the plasma is transferred, through tube 32, to pocket 30, after which the tube is heat sealed or welded and cut off.
- the plasma in pocket 30 is again fractionated, more particularly by cryo-precipitation, in order to isolate those components which are present in very small quantities in human blood and which possess therapeutical properties.
- the liquid fraction of the plasma is transferred, through tube 33, to pocket 31, during which transfer tube 34 is closed off, for example with a clamp.
- the rinsing solution in storage pocket 14 ispassed, through tube 34, into pocket 30 which contains the component separated by cryoprecipitation.
- the dead volume of the injection tube is as small as possible, and almost the entire amount of the solution contained in the storage pocket is injected.
- the injection means may be disconnected from access port 35 in pocket 14 and connected to a new pocket. It is thus possible to inject into the patients vein as many doses as may be required, with no fear of the fine injection tube becoming blocked.
- said means comprising:
- the inlet of said storage pocket being connected by sectionable tubing to said plurality of sampling and fractionating pockets, the outlet of said storage pocket being sealed and having means for being equipped with injection means;
- I a filter means for'preventing the injection of the agglomerated elements incorporated inside said storage pocket between said inlet and said outlet; said storage pocket being of dimensions substantially corresponding to the quantity of the component separated.
- said filter means consists of a tubular length of a filter fabric in the form of a sleeve running longitudinally inside said storage pocket,
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- External Artificial Organs (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7136734A FR2182578B1 (de) | 1971-10-13 | 1971-10-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3870042A true US3870042A (en) | 1975-03-11 |
Family
ID=9084287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US295687A Expired - Lifetime US3870042A (en) | 1971-10-13 | 1972-10-06 | Apparatus for separating and injecting blood component |
Country Status (16)
Country | Link |
---|---|
US (1) | US3870042A (de) |
JP (1) | JPS5146992B2 (de) |
AR (1) | AR199465A1 (de) |
AU (1) | AU450883B2 (de) |
BE (1) | BE788854A (de) |
BR (1) | BR7207166D0 (de) |
CA (1) | CA1018417A (de) |
CH (1) | CH571865A5 (de) |
DE (1) | DE2248265A1 (de) |
ES (1) | ES407377A1 (de) |
FR (1) | FR2182578B1 (de) |
GB (1) | GB1379083A (de) |
IL (1) | IL40480A (de) |
IT (1) | IT990508B (de) |
NL (1) | NL7213740A (de) |
SE (1) | SE398295B (de) |
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3986506A (en) * | 1974-09-03 | 1976-10-19 | Baxter Travenol Laboratories, Inc. | Apparatus for separation of cryoprecipitate from blood plasma and method |
DE2845365A1 (de) * | 1977-10-18 | 1979-04-19 | Baxter Travenol Lab | Druckwaechter- und stroemungskreisanordnung |
WO1984000905A1 (en) * | 1982-08-24 | 1984-03-15 | Baxter Travenol Lab | Blood component collection systems and methods |
US4474568A (en) * | 1982-01-21 | 1984-10-02 | Haemonetics Corporation | Multipurpose component container and anticoagulant bag |
EP0175274A2 (de) * | 1984-09-13 | 1986-03-26 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Methode zur Trennung von Blutbestandteilen |
US4680025A (en) * | 1982-08-24 | 1987-07-14 | Baxter Travenol Laboratories, Inc. | Blood component collection systems and methods |
US4915847A (en) * | 1987-08-04 | 1990-04-10 | Baxter International Inc. | Cryoglobulin separation |
US4917804A (en) * | 1986-10-31 | 1990-04-17 | Baxter International Inc. | Method and vessel for separation of cryoglobin |
US4985153A (en) * | 1988-06-23 | 1991-01-15 | Asahi Medical Co., Ltd. | Method for separating blood into blood components, and blood components separator unit |
US4994039A (en) * | 1985-11-15 | 1991-02-19 | Mattson Philip D | Apparatus and method for patients from a single donor or a restricted group of donors |
US5030215A (en) * | 1990-01-03 | 1991-07-09 | Cryolife, Inc. | Preparation of fibrinogen/factor XIII precipitate |
US5071570A (en) * | 1986-01-24 | 1991-12-10 | Terumo Corporation | Method for separation of blood components and apparatus thereof |
WO1992012684A1 (en) * | 1991-01-22 | 1992-08-06 | Baxter International Inc. | Blood container having lay-flat sample reservoir |
US5300060A (en) * | 1989-06-12 | 1994-04-05 | Miles Inc. | Blood bag system for separation and isolation of neocytes and gerocytes |
US5318782A (en) * | 1986-10-03 | 1994-06-07 | Weis Fogh Ulla S | Method for preparing tissue repair promoting substances |
US5399268A (en) * | 1989-09-12 | 1995-03-21 | Pall Corporation | Method for processing blood for human transfusion |
US5445736A (en) * | 1989-09-12 | 1995-08-29 | Pall Corporation | Device and filter element for processing blood for human transfusion |
US5462716A (en) * | 1991-11-11 | 1995-10-31 | Holm; Niels E. | Container for receiving and separating a fluid, preferably blood plasma, into its ingredients |
US5480378A (en) * | 1990-05-14 | 1996-01-02 | Weis-Fogh; Ulla | Apparatus for preparing a concentrate of coagulation factors from a blood sample |
US20030146170A1 (en) * | 2002-02-01 | 2003-08-07 | Frank Corbin | Whole blood collection and processing method |
US20030146162A1 (en) * | 1999-06-03 | 2003-08-07 | Metzel Peyton S. | Fluid processing sets and organizers for the same |
US20040238444A1 (en) * | 2003-05-27 | 2004-12-02 | Michael Ragusa | Continuous blood filtration and method of use |
US7025877B1 (en) | 1999-06-03 | 2006-04-11 | Baxter International Inc. | Processing set for processing and treating a biological fluid |
US20090148934A1 (en) * | 2006-06-20 | 2009-06-11 | General Biotechnology, Llc | Systems and Methods for Cryopreservation of Cells |
US20100196873A1 (en) * | 2006-06-20 | 2010-08-05 | Vialco, Llc | Systems and Methods for Cryopreservation of Cells |
WO2010136535A1 (de) * | 2009-05-27 | 2010-12-02 | Justus-Liebig-Universität Giessen | Vorrichtung und verfahren zur herstellung von blutprodukten |
US20170348468A1 (en) * | 2016-05-05 | 2017-12-07 | Spinesmith Partners, L.P. | Tissue collection and divertible suction valve |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2922957A1 (de) * | 1979-06-06 | 1980-12-18 | Mottaghy Khosrow | Verfahren und vorrichtung zum umwaelzen bzw. pumpen organisch-biologischer fluessigkeiten, insbesondere von blut |
GB2120568B (en) * | 1982-05-25 | 1985-12-24 | Lucas Ind Plc | Fuel filter |
CA1182758A (en) * | 1983-12-09 | 1985-02-19 | Anthony N. Sharpe | Apparatus for filtration |
WO1986001116A1 (en) * | 1984-08-09 | 1986-02-27 | Ruehland Dieter | Autotransfusion apparatus |
JPS63296763A (ja) * | 1987-05-29 | 1988-12-02 | Terumo Corp | 血液成分分画用器具 |
FR2690345B1 (fr) * | 1992-04-27 | 1996-06-21 | Cobe Lab | Procede et dispositif pour le transfert de liquide medical ou corporel. |
JP4935921B2 (ja) * | 2010-06-09 | 2012-05-23 | 株式会社ジェイ・エム・エス | 血液成分分配容器 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2702034A (en) * | 1950-07-20 | 1955-02-15 | Fenwal Inc | Apparatus for collecting, storing, and dispensing whole blood |
US2842122A (en) * | 1955-08-02 | 1958-07-08 | Cutter Lab | Filter |
US2848995A (en) * | 1949-07-06 | 1958-08-26 | Abbott Lab | Transfusion apparatus |
US3064647A (en) * | 1957-06-13 | 1962-11-20 | Baxter Laboratories Inc | Blood component separation method and apparatus |
US3110308A (en) * | 1960-10-20 | 1963-11-12 | Baxter Laboratories Inc | Parenteral fluid administration equiment |
US3187750A (en) * | 1963-01-15 | 1965-06-08 | Baxter Laboratories Inc | Multiple bag blood storage unit |
US3648693A (en) * | 1969-05-28 | 1972-03-14 | Jintan Terumo Co | Bag apparatus for transfusion of blood or fluid involving heat shrinkable tube means |
-
0
- BE BE788854D patent/BE788854A/xx not_active IP Right Cessation
-
1971
- 1971-10-13 FR FR7136734A patent/FR2182578B1/fr not_active Expired
-
1972
- 1972-10-02 DE DE19722248265 patent/DE2248265A1/de active Pending
- 1972-10-02 IL IL40480A patent/IL40480A/xx unknown
- 1972-10-04 GB GB4568772A patent/GB1379083A/en not_active Expired
- 1972-10-04 AU AU47363/72A patent/AU450883B2/en not_active Expired
- 1972-10-05 IT IT30095/72A patent/IT990508B/it active
- 1972-10-06 US US295687A patent/US3870042A/en not_active Expired - Lifetime
- 1972-10-06 ES ES407377A patent/ES407377A1/es not_active Expired
- 1972-10-06 JP JP47099986A patent/JPS5146992B2/ja not_active Expired
- 1972-10-11 NL NL7213740A patent/NL7213740A/xx not_active Application Discontinuation
- 1972-10-11 CA CA154,113A patent/CA1018417A/en not_active Expired
- 1972-10-11 CH CH1488172A patent/CH571865A5/xx not_active IP Right Cessation
- 1972-10-12 SE SE7213174A patent/SE398295B/xx unknown
- 1972-10-13 AR AR244617A patent/AR199465A1/es active
- 1972-10-13 BR BR007166/72A patent/BR7207166D0/pt unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2848995A (en) * | 1949-07-06 | 1958-08-26 | Abbott Lab | Transfusion apparatus |
US2702034A (en) * | 1950-07-20 | 1955-02-15 | Fenwal Inc | Apparatus for collecting, storing, and dispensing whole blood |
US2842122A (en) * | 1955-08-02 | 1958-07-08 | Cutter Lab | Filter |
US3064647A (en) * | 1957-06-13 | 1962-11-20 | Baxter Laboratories Inc | Blood component separation method and apparatus |
US3110308A (en) * | 1960-10-20 | 1963-11-12 | Baxter Laboratories Inc | Parenteral fluid administration equiment |
US3187750A (en) * | 1963-01-15 | 1965-06-08 | Baxter Laboratories Inc | Multiple bag blood storage unit |
US3648693A (en) * | 1969-05-28 | 1972-03-14 | Jintan Terumo Co | Bag apparatus for transfusion of blood or fluid involving heat shrinkable tube means |
Cited By (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3986506A (en) * | 1974-09-03 | 1976-10-19 | Baxter Travenol Laboratories, Inc. | Apparatus for separation of cryoprecipitate from blood plasma and method |
DE2845365A1 (de) * | 1977-10-18 | 1979-04-19 | Baxter Travenol Lab | Druckwaechter- und stroemungskreisanordnung |
US4474568A (en) * | 1982-01-21 | 1984-10-02 | Haemonetics Corporation | Multipurpose component container and anticoagulant bag |
WO1984000905A1 (en) * | 1982-08-24 | 1984-03-15 | Baxter Travenol Lab | Blood component collection systems and methods |
US4680025A (en) * | 1982-08-24 | 1987-07-14 | Baxter Travenol Laboratories, Inc. | Blood component collection systems and methods |
EP0175274A2 (de) * | 1984-09-13 | 1986-03-26 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Methode zur Trennung von Blutbestandteilen |
EP0175274A3 (en) * | 1984-09-13 | 1986-06-11 | Terumo Corp | Apparatus for separation of blood components |
US4994039A (en) * | 1985-11-15 | 1991-02-19 | Mattson Philip D | Apparatus and method for patients from a single donor or a restricted group of donors |
US5071570A (en) * | 1986-01-24 | 1991-12-10 | Terumo Corporation | Method for separation of blood components and apparatus thereof |
US5141645A (en) * | 1986-01-24 | 1992-08-25 | Terumo Corporation | Apparatus for separation of blood components |
US6284285B1 (en) | 1986-10-03 | 2001-09-04 | E. R. Squibb & Sons, Inc. | Tissue repair promoting composition |
US5318782A (en) * | 1986-10-03 | 1994-06-07 | Weis Fogh Ulla S | Method for preparing tissue repair promoting substances |
US5578326A (en) * | 1986-10-03 | 1996-11-26 | E. R. Squibb & Sons, Inc. | Method and an apparatus for preparing tissue repair promoting substances |
US4917804A (en) * | 1986-10-31 | 1990-04-17 | Baxter International Inc. | Method and vessel for separation of cryoglobin |
US4915847A (en) * | 1987-08-04 | 1990-04-10 | Baxter International Inc. | Cryoglobulin separation |
US4985153A (en) * | 1988-06-23 | 1991-01-15 | Asahi Medical Co., Ltd. | Method for separating blood into blood components, and blood components separator unit |
US5300060A (en) * | 1989-06-12 | 1994-04-05 | Miles Inc. | Blood bag system for separation and isolation of neocytes and gerocytes |
US5580465A (en) * | 1989-09-12 | 1996-12-03 | Pall Corporation | Method for preparing platelets |
US5543060A (en) * | 1989-09-12 | 1996-08-06 | Pall Corporation | Method for processing blood for human transfusion |
US5399268A (en) * | 1989-09-12 | 1995-03-21 | Pall Corporation | Method for processing blood for human transfusion |
US5445736A (en) * | 1989-09-12 | 1995-08-29 | Pall Corporation | Device and filter element for processing blood for human transfusion |
US5030215A (en) * | 1990-01-03 | 1991-07-09 | Cryolife, Inc. | Preparation of fibrinogen/factor XIII precipitate |
US5480378A (en) * | 1990-05-14 | 1996-01-02 | Weis-Fogh; Ulla | Apparatus for preparing a concentrate of coagulation factors from a blood sample |
US5167656A (en) * | 1991-01-22 | 1992-12-01 | Baxter International Inc. | Blood container having lay-flat sample reservoir |
WO1992012684A1 (en) * | 1991-01-22 | 1992-08-06 | Baxter International Inc. | Blood container having lay-flat sample reservoir |
US5674458A (en) * | 1991-11-11 | 1997-10-07 | E. R. Squibb & Sons, Inc. | Container for receiving and separating a fluid into its ingredients |
US5746979A (en) * | 1991-11-11 | 1998-05-05 | F. R, Squibb & Sons, Inc. | Method for receiving and separating a fluid into its ingredients |
US5462716A (en) * | 1991-11-11 | 1995-10-31 | Holm; Niels E. | Container for receiving and separating a fluid, preferably blood plasma, into its ingredients |
US5658533A (en) * | 1991-11-11 | 1997-08-19 | E.R. Squibb & Sons, Inc. | Container for receiving and separating a fluid into its ingredients |
US20060197031A1 (en) * | 1999-06-03 | 2006-09-07 | De Gheldere Serge | Processing set and methods for processing and treating a biological fluid |
US7445756B2 (en) | 1999-06-03 | 2008-11-04 | Fenwal, Inc. | Fluid processing sets and organizers for the same |
US20030146162A1 (en) * | 1999-06-03 | 2003-08-07 | Metzel Peyton S. | Fluid processing sets and organizers for the same |
US7425304B2 (en) | 1999-06-03 | 2008-09-16 | Fenwal, Inc. | Processing set and methods for processing and treating a biological fluid |
US7105093B2 (en) | 1999-06-03 | 2006-09-12 | Baxter International Inc. | Processing set and methods for processing and treating a biological fluid |
US7025877B1 (en) | 1999-06-03 | 2006-04-11 | Baxter International Inc. | Processing set for processing and treating a biological fluid |
US20050274673A1 (en) * | 2002-02-01 | 2005-12-15 | Gambro, Inc | Whole blood collection and processing method |
US20030146170A1 (en) * | 2002-02-01 | 2003-08-07 | Frank Corbin | Whole blood collection and processing method |
US6994790B2 (en) | 2002-02-01 | 2006-02-07 | Gambro, Inc. | Whole blood collection and processing method |
US7601268B2 (en) | 2003-05-27 | 2009-10-13 | Haemonetics Corporation | Continuous blood filtration and method of use |
US20040238444A1 (en) * | 2003-05-27 | 2004-12-02 | Michael Ragusa | Continuous blood filtration and method of use |
US8222027B2 (en) * | 2006-06-20 | 2012-07-17 | Cook General Biotechnolgy, LLC | Systems and methods for cryopreservation of cells |
US20100196873A1 (en) * | 2006-06-20 | 2010-08-05 | Vialco, Llc | Systems and Methods for Cryopreservation of Cells |
US20090148934A1 (en) * | 2006-06-20 | 2009-06-11 | General Biotechnology, Llc | Systems and Methods for Cryopreservation of Cells |
US8709797B2 (en) | 2006-06-20 | 2014-04-29 | Cook General Biotechnology Llc | Systems and methods for cryopreservation of cells |
US8936905B2 (en) | 2006-06-20 | 2015-01-20 | Cook General Biotechnology Llc | Systems and methods for cryopreservation of cells |
US9565854B2 (en) | 2006-06-20 | 2017-02-14 | Cook General Biotechnology Llc | Systems and methods for cryopreservation of cells |
US9877475B2 (en) | 2006-06-20 | 2018-01-30 | Cook General Biotechnology Llc | Systems and methods for cryopreservation of cells |
US10271543B2 (en) | 2006-06-20 | 2019-04-30 | Cook General Biotechnology Llc | Systems and methods for cryopreservation of cells |
WO2010136535A1 (de) * | 2009-05-27 | 2010-12-02 | Justus-Liebig-Universität Giessen | Vorrichtung und verfahren zur herstellung von blutprodukten |
US20120171658A1 (en) * | 2009-05-27 | 2012-07-05 | Justus-Liebig-Universität Giessen | Device and procedure for the manufacture of blood products |
US20170348468A1 (en) * | 2016-05-05 | 2017-12-07 | Spinesmith Partners, L.P. | Tissue collection and divertible suction valve |
US10232096B2 (en) * | 2016-05-05 | 2019-03-19 | Spinesmith Partners, L.P. | Tissue collection and divertible suction valve |
Also Published As
Publication number | Publication date |
---|---|
ES407377A1 (es) | 1975-10-16 |
CH571865A5 (de) | 1976-01-30 |
AR199465A1 (es) | 1974-09-09 |
CA1018417A (en) | 1977-10-04 |
DE2248265A1 (de) | 1973-04-19 |
JPS5146992B2 (de) | 1976-12-11 |
BE788854A (fr) | 1973-01-02 |
FR2182578A1 (de) | 1973-12-14 |
NL7213740A (de) | 1973-04-17 |
IL40480A0 (en) | 1972-12-29 |
IT990508B (it) | 1975-07-10 |
FR2182578B1 (de) | 1974-09-06 |
GB1379083A (en) | 1975-01-02 |
AU4736372A (en) | 1974-04-11 |
BR7207166D0 (pt) | 1973-07-26 |
AU450883B2 (en) | 1974-07-25 |
SE398295B (sv) | 1977-12-19 |
JPS4846187A (de) | 1973-07-02 |
IL40480A (en) | 1975-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3870042A (en) | Apparatus for separating and injecting blood component | |
US11963769B2 (en) | Blood sample optimization system and blood contaminant sequestration device and method | |
US2950716A (en) | Fluid handling method and apparatus | |
US3110308A (en) | Parenteral fluid administration equiment | |
US6387086B2 (en) | Blood processing set including an integrated blood sampling system | |
US7131958B2 (en) | Placental blood collection line including a rinsing bag | |
US7044941B2 (en) | Method and apparatus for collecting blood samples prior to a blood collection procedure | |
US2702034A (en) | Apparatus for collecting, storing, and dispensing whole blood | |
US3648693A (en) | Bag apparatus for transfusion of blood or fluid involving heat shrinkable tube means | |
CA2582301C (en) | Method and apparatus for blood sampling | |
USRE27132E (en) | Apparatus for treating blood | |
ES2726981T3 (es) | Sistema cerrado de extracción por vía IV integrado | |
DE4409842C2 (de) | Verfahren zum Erhalten einer Blutprobe aus der Nabelschnur eines neugeborenen Kindes | |
US3006341A (en) | Medical fluids handling and administering apparatus | |
US10512728B2 (en) | Filtering needle cap with a seal around a needle | |
US6730071B1 (en) | Collection, storage, transportation and sampling system and method of use thereof | |
US3078847A (en) | Blood handling method and apparatus | |
GB1591989A (en) | Container containing blood | |
US3485751A (en) | Dialyzer apparatus and method | |
EP0225861A1 (de) | Umfüllvorrichtung | |
TW477696B (en) | A bag system for collecting and storing blood and a method therefor | |
US20240374186A1 (en) | Blood sample optimization device | |
AU2005202959B2 (en) | Blood processing set including an integrated blood sampling system |