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US3720037A - Method and apparatus for packaging medicated gauze pads - Google Patents

Method and apparatus for packaging medicated gauze pads Download PDF

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Publication number
US3720037A
US3720037A US00200139A US3720037DA US3720037A US 3720037 A US3720037 A US 3720037A US 00200139 A US00200139 A US 00200139A US 3720037D A US3720037D A US 3720037DA US 3720037 A US3720037 A US 3720037A
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medication
gauze
web
package
furacin
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US00200139A
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E Jones
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Pioneer Laboratories Inc
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Pioneer Laboratories Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Definitions

  • the medication is distributed abandoned throughout the gauze so as to impregnate the gauze and the gauze web is then moved through a cooling [52] U S C] 53/21 FC 53/25 53/127 chamber to solidify the medication.
  • the medication B65b 55/14 impregnated web is then cut into sections of a [58] i 211:0 predetermined length and each of the sections are l ea c i folded. The folded section is then inserted into a flat package and sealed.
  • PATENTEDHARI3I973 13"720'037 STORAGE SEAL ING STATION c oouue CHAMBER Poucm'uc snmon FOLDING STATION m INVENTOR EDWARD w. JONES ia mg/vm ATTORNEKS are generally sealed in a flat envelope-like package under sterile conditions.
  • the packages generally comprise foil-lined laminated paper and may be rectangular in shape with three of the sides being sealed and the fourth side being open. After the pad has been inserted through the open side, the open side is then sealed.
  • the pad is inserted in the packet and the medication discharged into the packet after the gauze pad has been inserted therein.
  • the packet is then subjected to heat so that the medication may become distributed throughout the gauze. During the heating, there has been delamination of the paper of the packet. Also, the medicant has not been distributed evenly.
  • One of the objects of the present invention is to provide an improved method and apparatus for packaging medicated gauze pads.
  • a method of making a medicated pad package may comprise the steps of impregnating gauze with a medication in the viscous state.
  • the impregnated gauze and medication is then passed between rolls which have been set a predetermined distance apart so as to deposit a uniform, known quantity on the gauze.
  • the medication impregnated gauze is then placed in an envelope-like package which is subsequently sealed.
  • the gauze may .be in the form of a continuously moving web with a supply roll of the gauze and the impregnating of the gauze with a medication occurring within a heated chamber.
  • the impregnated gauze is then immediately transferred to a cooling chamber to solidify the medication.
  • An apparatus for making a medicated pad package may comprise a heated chamber having means therein for impregnating the medication in a viscous state onto a gauze pad.
  • the gauze may, for example, be passed through a bath of medicant, such as furacin.
  • Means which may be a cooling chamber is provided for solidifying the medication on the gauze. Sealing means are then employed to seal the gauze with the solidified medication into a relatively flat package.
  • FIG. 1 is a schematic view showing the several components of the apparatus according to the present invention with the heating chamber and cooling chamber being shown in vertical sections;
  • FIG. 2 is an overall perspective view showing the insertion of the medicated pad into an unsealed package
  • FIG. 3 is an overall perspective view showing the seal package according to the present invention.
  • a sterile roll of gauze 10 is mounted upon a shaft 11 within a heating chamber 12 maintained at a temperature of l26l 30F. or at the temperature necessary for the medicant involved.
  • the gauze is delivered from the supply roll in the form of a continuous web 13 which may move at a speed of about 4 yards per minute.
  • the gauze web 13 is moved over rollers through an impregnating pan 14 into which a supply of the medication is discharged through a supply line 15 leading from a supply container 16.
  • the medication may be either in liquid or viscous form.
  • the medication in a viscous form may be extruded upon the moving web.
  • the web emerges from the impregnating pan, it passes between a pair of parallel closely spaced stainless steel impregnation bars 17 which cause the medication to be evenly distributed throughout the gauze.
  • the bars 17 are spaced so that a uniform dosage of medication per unit area of gauze is obtained.
  • the gauze impregnated with medication is then quickly passed through a baffle area 18 so as to prevent condensation and then immediately moved into a cooling chamber 19 which is at a temperature of about F.
  • the cooling chamber may be of the type filled with dry ice at 20.
  • the cooling chamber solidifies the medication which has had a predetermined quantity impregnated throughout the gauze.
  • the web 13 Upon emerging from the cooling chamber, the web 13 will pass through a standard pressure nip 21 and then through automatically operated knives 22 which will cut the continuous web into sections of a predetermined length.
  • the sections indicated at 23 are carried along a continuous belt conveyor 24 to a folding station 25 where they may be folded by hand.
  • the folded pads 26 are then conveyed to a pouching station 27 where they are inserted into flat envelope-like packages 28 having an open edge 29 with the other edges being sealed as shown in FIG. 2.
  • the package 28 with the folded gauze pad therein is then conveyed to a sealing station 30 where the edge 29 is sealed at 31.
  • the sealed packages 32 are then delivered to a storage station.
  • the folding station may be suitable automatic machinery or the folding may be accomplished by hand.
  • Furacin the trademark of Norwich Pharmacal Company for its S-Nitro- Z-furaIdehyde-Semicarbazone.
  • Furacin was impregnated into the gauze in a particular spot and then melted to become uniformly distributed throughout the cloth. The melting occurred when the Furacin impregnated pads were subjected to heat treatment in a wicking oven at approximately l50F for about 1 hour. While the material would still be hot from the wicking oven, it would appear that the Furacin was evenly impregnated in the gauze pad. However, upon cooling, there occurred a definite separation of the blycols which form the Furacin base. Also, the paper became delaminated under heat.
  • Furacin is extruded onto a continuously moving gauze web having a width of three inches.
  • the gauze web with Furacin thereon is then passed between the impregnator bars to evenly distribute Furacin throughout the gauze and to provide an accurate dosage of Furacin per unit area of the gauze web.
  • the Furacin impregnated gauze web emerges from the cooling chamber, it is cut into 9-inch sections and each section is then folded twice by hand to result in a square gauze pad 3 inches along each side. The resulting pad is then packaged and sealed as described above.
  • the dry gauze weighs 0.75 grams, and 5 grams of Furacin, or six times the weight of the dry cloth, is impregnated throughout the gauze.
  • Furacin dressing may be extruded in a viscous state through a predetermined opening.
  • the gauze serves as a carrying web and in order to keep the Furacin stable, it is immediately introduced into a cooling chamber wherein the Furacin becomes preset in this extruded state within the cloth carrier. This results in very precise dimensions and thickness and provides very precise amounts of medication per square inch of gauze.
  • the Furacin is evenly distributed throughout the gauze pad on both surfaces at which point the Furacin is solidified so as to render it manageable and with a non-sticky smooth surface so that the impregnated gauze can be readily cut and folded and inserted into a package.
  • the present invention may also be employed with a number of different drugs or medicants in liquid or ointment form which solidify upon cooling.
  • the invention could also be used with similar results on either hot or cold medication assuming that at the starting points there is either a hot liquid that subsequently solidifies or a cold medication which is already solidified, such as an ointment.
  • a method of making a medicated pad package the steps of applying medication in a viscous state to gauze in a single web, quickly cooling the medication and gauze by subjecting the medication and gauze to sub-zero temperature to solidify the medication in a homogenous condition on the gauge so as to place a predetermined amount per unit area of medication on said gauze, thereafter placing the gauze with medication applied thereto into an envelope-like package, and sealing the package.

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  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)

Abstract

A supply roll of gauze or similar material in the form of a continuous web is enclosed within a heated chamber and passed through medication in viscous form so as to place it on the moving web within the heating chamber. The medication is distributed throughout the gauze so as to impregnate the gauze and the gauze web is then moved through a cooling chamber to solidify the medication. The medication impregnated web is then cut into sections of a predetermined length and each of the sections are folded. The folded section is then inserted into a flat package and sealed.

Description

O United States Patent 1 [111 3,720,037 Jones l lMal'ch 13, 1973 54| METHOD AND APPARATUS FOR 3,395,063 7/1968 Ralha ..53 25 x PACKAGING MEDICATED GAUZE 3,287,222 ll/l966 Larde et al. ..l28/l56 X PADS [75] Inventor: Edward W. Jones, Brigantine, NJ. Primary Exam'." Travis McGehee Attorney-Smythe & Moore [73] Assignee: Pioneer Laboratories, Inc., Pleasantvlne 57 ABSTRACT [22] Flled: 1971 A supply roll of gauze or similar material in the form [21 APPLNQ; 200 139 of a continuous web is enclosed within a heated chamber and passed through medication in viscous Related U-S- Applicati n D80! form so as to place it on the moving web within the [63] Continuation of Ser No 886 995 Dec 22 1969 heating chamber. The medication is distributed abandoned throughout the gauze so as to impregnate the gauze and the gauze web is then moved through a cooling [52] U S C] 53/21 FC 53/25 53/127 chamber to solidify the medication. The medication B65b 55/14 impregnated web is then cut into sections of a [58] i 211:0 predetermined length and each of the sections are l ea c i folded. The folded section is then inserted into a flat package and sealed.
[56] References Cited 8 Claims, 3 Drawing Figures UNITED STATES PATENTS 3,348,905 10/1967 Reveley ..53/2l R X COOLING CHAMBER 25 [30 r'otolus Z6 Q J' sen. me 3 To -c z ;v srmon sum" snnou STORAGE FIG.
PATENTEDHARI3I973 13"720'037 STORAGE SEAL ING STATION c oouue CHAMBER Poucm'uc snmon FOLDING STATION m INVENTOR EDWARD w. JONES ia mg/vm ATTORNEKS are generally sealed in a flat envelope-like package under sterile conditions. The packages generally comprise foil-lined laminated paper and may be rectangular in shape with three of the sides being sealed and the fourth side being open. After the pad has been inserted through the open side, the open side is then sealed.
In prior practice, the pad is inserted in the packet and the medication discharged into the packet after the gauze pad has been inserted therein. The packet is then subjected to heat so that the medication may become distributed throughout the gauze. During the heating, there has been delamination of the paper of the packet. Also, the medicant has not been distributed evenly.
One of the objects of the present invention is to provide an improved method and apparatus for packaging medicated gauze pads.
According to one aspect of the invention, a method of making a medicated pad package may comprise the steps of impregnating gauze with a medication in the viscous state. The impregnated gauze and medication is then passed between rolls which have been set a predetermined distance apart so as to deposit a uniform, known quantity on the gauze. The medication impregnated gauze is then placed in an envelope-like package which is subsequently sealed. The gauze may .be in the form of a continuously moving web with a supply roll of the gauze and the impregnating of the gauze with a medication occurring within a heated chamber. The impregnated gauze is then immediately transferred to a cooling chamber to solidify the medication.
An apparatus for making a medicated pad package may comprise a heated chamber having means therein for impregnating the medication in a viscous state onto a gauze pad. The gauze may, for example, be passed through a bath of medicant, such as furacin. Means which may be a cooling chamber is provided for solidifying the medication on the gauze. Sealing means are then employed to seal the gauze with the solidified medication into a relatively flat package.
Other objects, advantages and features of the present invention will be apparent from the accompanying description and drawings, which are merely exemplary.
In the drawings:
FIG. 1 is a schematic view showing the several components of the apparatus according to the present invention with the heating chamber and cooling chamber being shown in vertical sections;
FIG. 2 is an overall perspective view showing the insertion of the medicated pad into an unsealed package; and
FIG. 3 is an overall perspective view showing the seal package according to the present invention.
Proceeding next to the drawings wherein like reference symbols indicate the same parts throughout the various views, a specific embodiment of the present invention will be described in detail.
A sterile roll of gauze 10 is mounted upon a shaft 11 within a heating chamber 12 maintained at a temperature of l26l 30F. or at the temperature necessary for the medicant involved. The gauze is delivered from the supply roll in the form of a continuous web 13 which may move at a speed of about 4 yards per minute.
The gauze web 13 is moved over rollers through an impregnating pan 14 into which a supply of the medication is discharged through a supply line 15 leading from a supply container 16. The medication may be either in liquid or viscous form.
Instead of the impregnating pan 14, the medication in a viscous form may be extruded upon the moving web.
As the web emerges from the impregnating pan, it passes between a pair of parallel closely spaced stainless steel impregnation bars 17 which cause the medication to be evenly distributed throughout the gauze. The bars 17 are spaced so that a uniform dosage of medication per unit area of gauze is obtained.
The gauze impregnated with medication is then quickly passed through a baffle area 18 so as to prevent condensation and then immediately moved into a cooling chamber 19 which is at a temperature of about F. The cooling chamber may be of the type filled with dry ice at 20. The cooling chamber solidifies the medication which has had a predetermined quantity impregnated throughout the gauze.
This results in an even distribution of the medication on the gauze with a predetermined dosage of medication per square inch. Also, upon using the bandage there is no tendency for the bandage to stick to itself to the point where it removes medication from one layer to the other since the medication is preserved in its original state. This is particularly desirable where sections of the gauze are cut and folded into pads. Further, no chemical changes or adulterations are made in the medication.
Upon emerging from the cooling chamber, the web 13 will pass through a standard pressure nip 21 and then through automatically operated knives 22 which will cut the continuous web into sections of a predetermined length. The sections indicated at 23 are carried along a continuous belt conveyor 24 to a folding station 25 where they may be folded by hand. The folded pads 26 are then conveyed to a pouching station 27 where they are inserted into flat envelope-like packages 28 having an open edge 29 with the other edges being sealed as shown in FIG. 2. The package 28 with the folded gauze pad therein is then conveyed to a sealing station 30 where the edge 29 is sealed at 31. The sealed packages 32 are then delivered to a storage station.
The folding station may be suitable automatic machinery or the folding may be accomplished by hand.
While the present invention may be employed with a great number of medications which are in liquid or viscous form and solidify upon cooling, the invention is particularly suitable to the use of Furacin, the trademark of Norwich Pharmacal Company for its S-Nitro- Z-furaIdehyde-Semicarbazone. In previous methods Furacin was impregnated into the gauze in a particular spot and then melted to become uniformly distributed throughout the cloth. The melting occurred when the Furacin impregnated pads were subjected to heat treatment in a wicking oven at approximately l50F for about 1 hour. While the material would still be hot from the wicking oven, it would appear that the Furacin was evenly impregnated in the gauze pad. However, upon cooling, there occurred a definite separation of the blycols which form the Furacin base. Also, the paper became delaminated under heat.
With the present invention, Furacin is extruded onto a continuously moving gauze web having a width of three inches. The gauze web with Furacin thereon is then passed between the impregnator bars to evenly distribute Furacin throughout the gauze and to provide an accurate dosage of Furacin per unit area of the gauze web.
After the Furacin impregnated gauze web emerges from the cooling chamber, it is cut into 9-inch sections and each section is then folded twice by hand to result in a square gauze pad 3 inches along each side. The resulting pad is then packaged and sealed as described above.
In the case of Furacin, the dry gauze weighs 0.75 grams, and 5 grams of Furacin, or six times the weight of the dry cloth, is impregnated throughout the gauze. With the present invention, Furacin dressing may be extruded in a viscous state through a predetermined opening. The gauze serves as a carrying web and in order to keep the Furacin stable, it is immediately introduced into a cooling chamber wherein the Furacin becomes preset in this extruded state within the cloth carrier. This results in very precise dimensions and thickness and provides very precise amounts of medication per square inch of gauze. The Furacin is evenly distributed throughout the gauze pad on both surfaces at which point the Furacin is solidified so as to render it manageable and with a non-sticky smooth surface so that the impregnated gauze can be readily cut and folded and inserted into a package.
The present invention may also be employed with a number of different drugs or medicants in liquid or ointment form which solidify upon cooling. The invention could also be used with similar results on either hot or cold medication assuming that at the starting points there is either a hot liquid that subsequently solidifies or a cold medication which is already solidified, such as an ointment.
It will be understood that various details of construction and arrangement of parts may be made without departing from the spirit of the invention.
What is claimed is:
1. In a method of making a medicated pad package, the steps of applying medication in a viscous state to gauze in a single web, quickly cooling the medication and gauze by subjecting the medication and gauze to sub-zero temperature to solidify the medication in a homogenous condition on the gauge so as to place a predetermined amount per unit area of medication on said gauze, thereafter placing the gauze with medication applied thereto into an envelope-like package, and sealing the package.
2. In a method as claimed in claim 1 with said web of gauze being delivered from a supply roll, the supply roll and application of medication to the gauze being under heated conditions.
3. In a method as claimed in claim 1 with the step of applying being extrusion of the medication in viscous form onto the moving web of gauze.
4. In an apparatus for making a medicated pad package, the combination of means for placing a medication in a viscous state onto a single web of gauze, means for quickly solidifying a predetermined amount of the medication per unit area on the gauze at sub-zero temperature, and means for thereafter placing and sealing the gauze with the solidified medication into a relatively flat envelope-like package.
5. In an apparatus as claimed in claim 4 and including a pair of closely spaced parallel bars set a predetermined distance apart between which the gauze with the applied medication is passed so as to place a predetermined quantity of medication on each square inch thereof.
6. In a method as claimed in claim 1 wherein the medication is 5-Nitro-2-furaldehyde- Semicarbazone.
7. In an apparatus as claimed in claim 4 wherein the medication is S-Nitro-2-furaldehydeSemicarbazone.
8. In a method as claimed in claim 1 including the step of folding the impregnated web before placing into the envelope-like package.

Claims (7)

1. In a method of making a medicated pad package, the steps of applying medication in a viscous state to gauze in a single web, quickly cooling the medication and gauze by subjecting the medication and gauze to sub-zero temperature to solidify the medication in a homogenous condition on the gauge so as to place a predetermined amount per unit area of medication on said gauze, thereafter placing the gauze with medication applied thereto into an envelope-like package, and sealing the package.
2. In a method as claimed in claim 1 with said web of gauze being delivered from a supply roll, the supply roll and application of medication to the gauze being under heated conditions.
3. In a method as claimed in claim 1 with the step of applying being extrusion of the medication in viscous form onto the moving web of gauze.
4. In an apparatus for making a medicated pad package, the combination of means for placing a medication in a viscous state onto a single web of gauze, means for quickly solidifying a predetermined amount of the medication per unit area on the gauze at sub-zero temperature, and means for thereafter placing and sealing the gauze with the solidified medication into a relatively flat envelope-like package.
5. In an apparatus as claimed in claim 4 and including a pair of closely spaced parallel bars set a predetermined distance apart between which the gauze with the applied medication is passed so as to place a predetermined quantity of medication on each square inch thereof.
6. In a method as claimed in claim 1 wherein the medication is 5-Nitro-2-furaldehyde- Semicarbazone.
7. In an apparatus as claimed in claim 4 wherein the medication is 5-Nitro-2-furaldehyde-Semicarbazone.
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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3913299A (en) * 1973-05-21 1975-10-21 Alfa Laval Ab Apparatus for enveloping and treating substances
US3961458A (en) * 1974-07-05 1976-06-08 Svenska Textilforskningsinstitutet Pretreatment, packing, storing and finishing treatment of textile material products
WO1985003275A1 (en) * 1984-01-23 1985-08-01 Laipply Thomas C Alcohol wipe and methods
US4689935A (en) * 1971-02-25 1987-09-01 Harding Audrey E Antiseptic glove
US4696393A (en) * 1981-10-19 1987-09-29 Laipply Thomas C Applicator wipe for inviscid fluids
US5044141A (en) * 1990-07-11 1991-09-03 Franchi Richard M Method for sterile packaging and wetting of articles
US5046608A (en) * 1981-10-19 1991-09-10 Laipply Thomas C Combined fluid storage container and applicator device and method
US5651652A (en) * 1996-09-19 1997-07-29 Williams; David J. Breakaway tamperproof fastener
US5669207A (en) * 1995-06-23 1997-09-23 H.B. Fuller Licensing & Financing, Inc. Method for tackless packaging of hot melt adhesive
US5682758A (en) * 1994-05-10 1997-11-04 Petro Source Refining Partners Method and apparatus for cooling asphalt
US8956466B2 (en) 2011-08-01 2015-02-17 Texwipe (a division of Illinois Tool Works Inc.) Process for preparing sorptive substrates, and integrated processing system for substrates
US11185495B2 (en) 2017-11-01 2021-11-30 Clexio Biosciences Ltd. Finished fibrous structures and methods of their use and preparation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3287222A (en) * 1962-03-16 1966-11-22 Roussel Uclaf Method for preparation of synthetic fiber medical dressing impregnated with therapeutic
US3348905A (en) * 1967-10-24 Method for sterilization of an ointment impregnated gauze
US3395063A (en) * 1962-04-10 1968-07-30 Pires And Mourato Vermelho Process for the preparation of sterile dressings

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3348905A (en) * 1967-10-24 Method for sterilization of an ointment impregnated gauze
US3287222A (en) * 1962-03-16 1966-11-22 Roussel Uclaf Method for preparation of synthetic fiber medical dressing impregnated with therapeutic
US3395063A (en) * 1962-04-10 1968-07-30 Pires And Mourato Vermelho Process for the preparation of sterile dressings

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689935A (en) * 1971-02-25 1987-09-01 Harding Audrey E Antiseptic glove
US3913299A (en) * 1973-05-21 1975-10-21 Alfa Laval Ab Apparatus for enveloping and treating substances
US3961458A (en) * 1974-07-05 1976-06-08 Svenska Textilforskningsinstitutet Pretreatment, packing, storing and finishing treatment of textile material products
US4696393A (en) * 1981-10-19 1987-09-29 Laipply Thomas C Applicator wipe for inviscid fluids
US5046608A (en) * 1981-10-19 1991-09-10 Laipply Thomas C Combined fluid storage container and applicator device and method
WO1985003275A1 (en) * 1984-01-23 1985-08-01 Laipply Thomas C Alcohol wipe and methods
US5044141A (en) * 1990-07-11 1991-09-03 Franchi Richard M Method for sterile packaging and wetting of articles
US5682758A (en) * 1994-05-10 1997-11-04 Petro Source Refining Partners Method and apparatus for cooling asphalt
US5669207A (en) * 1995-06-23 1997-09-23 H.B. Fuller Licensing & Financing, Inc. Method for tackless packaging of hot melt adhesive
US5651652A (en) * 1996-09-19 1997-07-29 Williams; David J. Breakaway tamperproof fastener
US8956466B2 (en) 2011-08-01 2015-02-17 Texwipe (a division of Illinois Tool Works Inc.) Process for preparing sorptive substrates, and integrated processing system for substrates
US11185495B2 (en) 2017-11-01 2021-11-30 Clexio Biosciences Ltd. Finished fibrous structures and methods of their use and preparation

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