US2052321A - Treatment of sinuses - Google Patents
Treatment of sinuses Download PDFInfo
- Publication number
- US2052321A US2052321A US736863A US73686334A US2052321A US 2052321 A US2052321 A US 2052321A US 736863 A US736863 A US 736863A US 73686334 A US73686334 A US 73686334A US 2052321 A US2052321 A US 2052321A
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- Prior art keywords
- sinuses
- bulb
- medicine
- nostril
- air
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Definitions
- This invention relates to the 'treatrnentof sinuses and has for an object the provision of a novel, inexpensive, and elfective method and apparatus for introducing medicine thereinto.
- the introducing of medicine through thenostrils into adjacent sinuses has long presented a problem becauseof the shape andlocation of these passages and of the air at atmospheric pressure therein.
- Attempts to solve the problem have resulted in the production of special apparatus wherein there is 'placed the medicine to be introduced and whichapparatusis designed to evacuate air from the sinuses and thereafter to introduce the medicine into the sinuses through the nostrils.
- Such apparatus is'highly -expensive and is usually to -be foundonly in the offices'of doctors-who arespecial'ists in sinus treatment.
- My invention provides for the-expeditious and effective introduction of medicine into the sinuses in a novel and simple manner, which avoids the necessity of costly apparatus and which may be carried out in the patients home and by the patient himself.
- the invention in 'this -connection follows from my discovery that itis unnecessary to reduce the air pressure in the'sinuses before the medicine is placed in the nostril, and that the desired reduction of pressure may be readily-accomplishedafter the medicine is'in the nostril.
- a further feature of the-invention resides in the provision of a novel method and apparatus for applying suction to sin-uses fer the withdrawal-of pus or other foreignmatter therefrom.
- the invention, together'with further-objects and advantages thereof, will i be best-understood from the ensuing descriptiongand its scope from the claims appended hereto. 7
- Fig. l is a view in elevation, partly'insection and with parts broken away,--showing a form of apparatus for evacuating air from sinuses in the practice of'my invention.
- Fig. 2 is a-detail'view showing different sizes of rubber bulbs'whichmay be interchangeably employed withtheapparatus of Fig. 1.
- Fig. 3 is a-view illustrating the carrying out of theinvention with the apparatus of Fig. 1.
- Fig. 4 is an elevational view of an alternative form of air-evacuating apparatus.
- Fig. 5 is a detailview showing a further modification of said apparatus.
- Fig. 6 is an elevational view showing a further modified form of suction or air-evacuating apparatus especiallyadapted for the withdrawal of undesirable material from sinuses prior to the introducing of the medicine.
- one form of apparatus for reducing the air pressure in the sinuses in the carrying out of my invention may, as shown in Fig. 1, comprise a tube 5, having connected to one end thereof a cap or bulb 6,
- the cap or bulb 6 may conveniently be fitted overone end of a tubular fitting 8 of hard rubber or the like, the other end of which fitting is firmly engagedin one end of the tubext.
- a member compressible and expansible to produce a negative pressure such as a bulb 9 of rubber or like material, which bulb may be connected with the-tube 5 through'fitting Iii similar to the fitting 8 aforesaid.
- the bulb 9 may bethe bulb of a conventional atomizer with the exception that the valve I I is reversed so that air is evacuated through the valve when said bulb 9 is .compressed.
- valve H cooperates with a passage H2 in the fitting I 3 in an end of the bulb 9, which fitting may be of a conventional type, having suitable retaining members such as indicated at M, for maintaining the valve in as q Sild relation to the fitting.
- the valve II permits air to flow freely from the interior of the bulb through the passage 12 to the outside of the bulb; but when the latter is thereafter released, the valve aforesaid blocks the passage l2 and prevents air from entering into the bulb through said passage.
- the patient first lies on his back as indicated in Fig. 3. Then the desired amount of medicine (argyrol, for example) with which the sinuses are to be treated is introduced intoone of the nostrils l5 in any convenient way, as by an ordinary medicine dropper.
- the'medicine in the nostril is indicated at 96, while the numerals l7, [8 refer to diagrammatic representations of sinuses commun-i'cating withsaid nostril.
- the bulb or cap '6 is new inserted into the nostril l5 and the bulb 9 is compressed, with resultant evacuation of the air from said-bulb 9 through the aforesaid passage 12.
- Bulb *9 is nowreleasedywhereupon air from the sinuses passes through the medicine in the nostril and into the bulb, equalizing the pressures in the bulb and sinuses and producing less than atmospheric pressure in the sinuses.
- the pressure on the bulb 9 is released-as aforesaid, the patient-should swallow or maintain the soft palate in such-position as to close communication between the'mouth and nose, and at the same time should hold closedthe nostril into which the cap t has not been inserted, thereby insuring flow of airfromthe sinuses into bulb 9 and consequent reduction of air pressure in said sinuses.
- the cap 6 is withdrawn from the-nostril, whereupon the pressure of the atmosphere forces the medicine from said nostril intothe sinuses.
- the degree of pressure reduction obtained by a given extent of compression of the bulb 9 and the subsequent release thereof is of course dependent upon the size of the bulb and its resilience, and such size and resilience may be varied as desired.
- the tube 5 may be of rubber of suitable stiffness or of any other suitable material, and of any convenicnt shape. It will be apparent that if desired the tube 5 may be shaped to fit the nostril, in which event the cap aforesaid may be dispensed with.
- my invention may be applied to the introduction of medicine into. sinuses through both nostrils simultaneously.
- pressure reducing apparatus such as shown in Fig. 4 may be utilized.
- Such apparatus may comprise twin tubes 5, 5, each with a cap 6 at one end, which tubes at their other ends are applied to the Y shaped fitting I9.
- the latter is shown as comprising diverging branches I9, 19 for engagement by said tubes and a vertical branch IQ for insertion into the bulb 9.
- the caps E5, 6 may be applied concurrently to both nostrils, following the insertion of medicine therein; whereupon by pressing and releasing the bulb 9 the pressure in the sinuses communicating with said nostrils will be reduced and upon withdrawal of the apparatus the medicine will be forced by the atmosphere from said nostrils and into said sinuses.
- the tubular fitting 8 may have mounted thereon a valve 28 normally maintained by a spring 2
- the operator can retract the valve 20, following the creation of reduced pressure in the sinus, thus admitting air at atmospheric pressure into said fitting and thence into the nostril, with consequent driving of the medicine into the sinus.
- the embodiment of Fig. 5 need not include the valve ll of Figs. 1 and 3, since the spring 2
- Fig, 6 I have shown a form of my invention especially adapted for this purpose.
- the tube 5, and bulb 9 may be of the same construction, and equipped with the same valve. II, as hereinbefore described.
- a fitting 8" Inserted into the opposite end of the tube 5, there is shown a fitting 8" having at one end a cap 6 insertible into the nostril.
- the fitting 8" may comprise an enlarged intermediate basin portion 24.
- Means for causing the introduction of medicine into a sinus comprising a manually compressible element connectable to only one nostril, a single tube extending from one end of said element and having a cap for insertion into said nostril, valve means carried by said element at its other end adapted to enable air to flow from said element through said other end when said element is compressed and adapted to prevent a flow of air through said end into the interior of said element when pressure thereon is released, whereby, upon release of pressure on said element following insertion of said cap into said nostril after the introduction of medicine into said nostril, air is drawn from said sinus through said medicine and the pressure in said sinus is reduced.
- Means for causing the introduction of medicine into a sinus comprising a manually compressible element connectable to only one nostril, a single tube extending from one end of said element and having a flexible bulb for insertion into said nostril, valve means carried by said element at its other end adapted to enable air to flow from said element through said other end when said element is compressed and adapted to prevent a flow of air through said end into the interior of said element when pressure thereon is released, whereby, upon release of pressure on said element following insertion of said flexible bulb into said nostril after the introduction of medicine into said nostril, air is drawn from said sinus through said medicine and the pressure in said sinus is reduced.
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
Aug. 25, 1936. H. v. SMART TREATMENT OF SINUSES Filed July 25, 1934 2 She'ets-Shecft 1' INVENTOR H ATTORNEY 'H.V. SMART TREATMENT OF SINUSES Filed July 25, 1934 2 Sheets-Sheet 2 Manta, VLYZEQ M ATTORNEY Patented Aug. 25, 1936 UNITED STATES PATENT OFFICE 2 Claims.
This invention relates to the 'treatrnentof sinuses and has for an object the provision of a novel, inexpensive, and elfective method and apparatus for introducing medicine thereinto. The introducing of medicine through thenostrils into adjacent sinuses has long presented a problem becauseof the shape andlocation of these passages and of the air at atmospheric pressure therein. Attempts to solve the problem have resulted in the production of special apparatus wherein there is 'placed the medicine to be introduced and whichapparatusis designed to evacuate air from the sinuses and thereafter to introduce the medicine into the sinuses through the nostrils. Such apparatus is'highly -expensive and is usually to -be foundonly in the offices'of doctors-who arespecial'ists in sinus treatment. My inventionprovides for the-expeditious and effective introduction of medicine into the sinuses in a novel and simple manner, which avoids the necessity of costly apparatus and which may be carried out in the patients home and by the patient himself. The invention in 'this -connection follows from my discovery that itis unnecessary to reduce the air pressure in the'sinuses before the medicine is placed in the nostril, and that the desired reduction of pressure may be readily-accomplishedafter the medicine is'in the nostril. A further feature of the-invention resides in the provision of a novel method and apparatus for applying suction to sin-uses fer the withdrawal-of pus or other foreignmatter therefrom. The invention, together'with further-objects and advantages thereof, will i be best-understood from the ensuing descriptiongand its scope from the claims appended hereto. 7
In the accompanyingdrawings:
Fig. l is a view in elevation, partly'insection and with parts broken away,--showing a form of apparatus for evacuating air from sinuses in the practice of'my invention.
Fig. 2 is a-detail'view showing different sizes of rubber bulbs'whichmay be interchangeably employed withtheapparatus of Fig. 1.
Fig. 3 is a-view illustrating the carrying out of theinvention with the apparatus of Fig. 1.
Fig. 4 is an elevational view of an alternative form of air-evacuating apparatus.
Fig. 5 is a detailview showing a further modification of said apparatus.
Fig. 6 is an elevational view showing a further modified form of suction or air-evacuating apparatus especiallyadapted for the withdrawal of undesirable material from sinuses prior to the introducing of the medicine.
Referring to the drawings, one form of apparatus for reducing the air pressure in the sinuses in the carrying out of my invention may, as shown in Fig. 1, comprise a tube 5, having connected to one end thereof a cap or bulb 6,
which vmay-for example,bethe bulb of an ordinary medicine dropper having one or more holes 1 therein. The cap or bulb 6 may conveniently be fitted overone end of a tubular fitting 8 of hard rubber or the like, the other end of which fitting is firmly engagedin one end of the tubext. At its opposite end said'tube communicates with a member compressible and expansible to produce a negative pressure, such as a bulb 9 of rubber or like material, which bulb may be connected with the-tube 5 through'fitting Iii similar to the fitting 8 aforesaid. The bulb 9 may bethe bulb of a conventional atomizer with the exception that the valve I I is reversed so that air is evacuated through the valve when said bulb 9 is .compressed. As shown, the valve H cooperates with a passage H2 in the fitting I 3 in an end of the bulb 9, which fitting may be of a conventional type, having suitable retaining members such as indicated at M, for maintaining the valve in as q sembled relation to the fitting. When the bulb 9 is compressed, the valve II permits air to flow freely from the interior of the bulb through the passage 12 to the outside of the bulb; but when the latter is thereafter released, the valve aforesaid blocks the passage l2 and prevents air from entering into the bulb through said passage.
In the practice of my invention the patient first lies on his back as indicated in Fig. 3. Then the desired amount of medicine (argyrol, for example) with which the sinuses are to be treated is introduced intoone of the nostrils l5 in any convenient way, as by an ordinary medicine dropper. In Fig. 3 the'medicine in the nostril is indicated at 96, while the numerals l7, [8 refer to diagrammatic representations of sinuses commun-i'cating withsaid nostril. The bulb or cap '6 is new inserted into the nostril l5 and the bulb 9 is compressed, with resultant evacuation of the air from said-bulb 9 through the aforesaid passage 12. Bulb *9 is nowreleasedywhereupon air from the sinuses passes through the medicine in the nostril and into the bulb, equalizing the pressures in the bulb and sinuses and producing less than atmospheric pressure in the sinuses. When the pressure on the bulb 9 is released-as aforesaid, the patient-should swallow or maintain the soft palate in such-position as to close communication between the'mouth and nose, and at the same time should hold closedthe nostril into which the cap t has not been inserted, thereby insuring flow of airfromthe sinuses into bulb 9 and consequent reduction of air pressure in said sinuses. Following said reduction of pressure, the cap 6 is withdrawn from the-nostril, whereupon the pressure of the atmosphere forces the medicine from said nostril intothe sinuses. The foregoing method of introduction of medicine into sinuses has been tested repeatedly and found thoroughly eificacious and satisfactory. The reduction of pressure in the sinuses following the introduction of the medicine into the nostril takes place readily and expeditiously, and upon removal of the pressurereducing apparatus from the nostril the medicine is forced promptly into the sinuses by the action of the atmosphere. The introduction of the medicine should of course preferably be preceded by treatment of the sinus for the withdrawal of pus or other foreign matter therefrom as is well understood in the art. It will be apparent that the invention avoids the necessity of expensive apparatus and that it may be carried out with facility in the patients home. The invention provides, in short, for the facile introduction of the medicine in an inexpensive, convenient, and efiicient manner.
The degree of pressure reduction obtained by a given extent of compression of the bulb 9 and the subsequent release thereof is of course dependent upon the size of the bulb and its resilience, and such size and resilience may be varied as desired.
Different sizes of caps, such as 6, E5, 6" (Fig. 2) for difierent sizes of nostrils may be interchangeably applied to the tube 5, as will be apparent. The tube 5 may be of rubber of suitable stiffness or of any other suitable material, and of any convenicnt shape. It will be apparent that if desired the tube 5 may be shaped to fit the nostril, in which event the cap aforesaid may be dispensed with.
If desired, my invention may be applied to the introduction of medicine into. sinuses through both nostrils simultaneously. For this purpose, pressure reducing apparatus such as shown in Fig. 4 may be utilized. Such apparatus may comprise twin tubes 5, 5, each with a cap 6 at one end, which tubes at their other ends are applied to the Y shaped fitting I9. The latter is shown as comprising diverging branches I9, 19 for engagement by said tubes and a vertical branch IQ for insertion into the bulb 9. With this apparatus the caps E5, 6 may be applied concurrently to both nostrils, following the insertion of medicine therein; whereupon by pressing and releasing the bulb 9 the pressure in the sinuses communicating with said nostrils will be reduced and upon withdrawal of the apparatus the medicine will be forced by the atmosphere from said nostrils and into said sinuses.
The withdrawal of the apparatus from the nostril to subject the medicine to atmospheric pressure may be avoided by providing manually operable means in connection therewith for placing the interior thereof in communication with the atmosphere while the apparatus remains inserted in the nostril. Thus, as indicated in Fig. 5, the tubular fitting 8 may have mounted thereon a valve 28 normally maintained by a spring 2| in the position shown, wherein air cannot pass through the opening 22 into said fitting. By pressing upon the lever 23, however, the operator can retract the valve 20, following the creation of reduced pressure in the sinus, thus admitting air at atmospheric pressure into said fitting and thence into the nostril, with consequent driving of the medicine into the sinus. It will be readily understood that the embodiment of Fig. 5 need not include the valve ll of Figs. 1 and 3, since the spring 2| may be of such tension as to yield readily to permit the escape of air during compression of the bulb 9. The valve ll may, however, be retained if desired.
While the sinuses may have pus and other matter withdrawn therefrom by means wellknown in the art, prior to the introduction of the medicine as above described, such matter may be readily withdrawn by apparatus of the type hereinbefore described for creating reduced pressure in the sinuses. In Fig, 6, I have shown a form of my invention especially adapted for this purpose. In this embodiment, the tube 5, and bulb 9 may be of the same construction, and equipped with the same valve. II, as hereinbefore described. Inserted into the opposite end of the tube 5, there is shown a fitting 8" having at one end a cap 6 insertible into the nostril. The fitting 8", as shown, may comprise an enlarged intermediate basin portion 24. Upon the insertion of the cap 6 into the nostril and compression of the bulb 9, air is evacuated from the outer end of said bulb; and upon then releasing said bulb the latter expands and reduces the pressure in the sinuses, drawing air therefrom together with pus and foreign matter therein. In other words, suction is applied to said sinuses with resultant withdrawal of detrimental matter therefrom. The pus and other undesirable matter is caught in the basin portion 24 of the fitting 8" while the air continues its travel into and through the bulb 9.
The terms and expressions which I have. em-
ployed are used as terms of description and not of limitation, and I have no intention, in the use of such terms and expressions, of excluding equivalents of the features shown and described or portions thereof, but recognize that various modifications are possible within the scope of the in uention claimed.
I claim:
1. Means for causing the introduction of medicine into a sinus, said means comprising a manually compressible element connectable to only one nostril, a single tube extending from one end of said element and having a cap for insertion into said nostril, valve means carried by said element at its other end adapted to enable air to flow from said element through said other end when said element is compressed and adapted to prevent a flow of air through said end into the interior of said element when pressure thereon is released, whereby, upon release of pressure on said element following insertion of said cap into said nostril after the introduction of medicine into said nostril, air is drawn from said sinus through said medicine and the pressure in said sinus is reduced.
2. Means for causing the introduction of medicine into a sinus, said means comprising a manually compressible element connectable to only one nostril, a single tube extending from one end of said element and having a flexible bulb for insertion into said nostril, valve means carried by said element at its other end adapted to enable air to flow from said element through said other end when said element is compressed and adapted to prevent a flow of air through said end into the interior of said element when pressure thereon is released, whereby, upon release of pressure on said element following insertion of said flexible bulb into said nostril after the introduction of medicine into said nostril, air is drawn from said sinus through said medicine and the pressure in said sinus is reduced.
HARRY VINCENT SMART.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US736863A US2052321A (en) | 1934-07-25 | 1934-07-25 | Treatment of sinuses |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US736863A US2052321A (en) | 1934-07-25 | 1934-07-25 | Treatment of sinuses |
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US2052321A true US2052321A (en) | 1936-08-25 |
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US736863A Expired - Lifetime US2052321A (en) | 1934-07-25 | 1934-07-25 | Treatment of sinuses |
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Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3848607A (en) * | 1971-10-29 | 1974-11-19 | M Clair | Therapeutic apparatus |
US4921488A (en) * | 1988-01-15 | 1990-05-01 | Maitz Carlos A | Aspirator device for body fluids |
US5114415A (en) * | 1989-06-14 | 1992-05-19 | Susan Shedlock | Apparatus for suctioning secretions from upper airways |
WO1992021404A1 (en) * | 1991-05-31 | 1992-12-10 | Bechgaard International Research And Development A/S | Nasal dispenser actuated by nose contact |
US5290257A (en) * | 1992-01-02 | 1994-03-01 | Zhong Being Tang | Method and apparatus for de-airing the heart |
US5599304A (en) * | 1994-05-10 | 1997-02-04 | Mount Sinai School Of Medicine Of The City University Of New York | Sinonasal suction apparatus |
US6494204B1 (en) * | 2000-06-23 | 2002-12-17 | Pedro D. Ponce | Nasal medication administering device |
US6820571B2 (en) | 2001-01-26 | 2004-11-23 | George J. Cory | Manually operated animal training device |
US20070289907A1 (en) * | 2006-06-09 | 2007-12-20 | Vanhulzen Chad | System and methods for maintaining an aquarium ecosystem |
EP2036527A1 (en) * | 2007-09-13 | 2009-03-18 | Siemens & Co. Heilwasser und Quellenprodukte des Staatsbades Bad Ems GmbH & Co. KG | Nasal spray with non-return valve |
US20090202665A1 (en) * | 2008-02-13 | 2009-08-13 | Bekan Rhinologics Inc. | Nasal irrigation device |
US20100274164A1 (en) * | 2007-05-16 | 2010-10-28 | Rhinomed Ab | Vibration device |
US20110166523A1 (en) * | 2008-02-13 | 2011-07-07 | Javer Amin R | Nasal irrigation device |
US20130158449A1 (en) * | 2011-12-16 | 2013-06-20 | Chordate Medical Ag | Double stimulation |
US20130158448A1 (en) * | 2011-12-16 | 2013-06-20 | Chordate Medical Ag | Stimulation of hypothalamus |
US20130158450A1 (en) * | 2011-12-16 | 2013-06-20 | Chordate Medical Ag | Treatment of headache disorders |
US9198618B2 (en) | 2011-12-16 | 2015-12-01 | Chordate Medical Ab | Pressure sensing system and method |
US9474684B2 (en) | 2012-03-20 | 2016-10-25 | Chordate Medical Ab | Electroactive vibration method |
US9486381B2 (en) | 2011-12-16 | 2016-11-08 | Chordate Medical Ab | ALS treatment |
US9872814B2 (en) | 2012-03-20 | 2018-01-23 | Chordate Medical Ag | Vibration pattern for vibration stimulation |
US11285072B2 (en) * | 2017-03-28 | 2022-03-29 | Abilion Medical Systems Ab | Devices, systems and methods for mechanical tissue stimulation |
-
1934
- 1934-07-25 US US736863A patent/US2052321A/en not_active Expired - Lifetime
Cited By (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3848607A (en) * | 1971-10-29 | 1974-11-19 | M Clair | Therapeutic apparatus |
US4921488A (en) * | 1988-01-15 | 1990-05-01 | Maitz Carlos A | Aspirator device for body fluids |
US5114415A (en) * | 1989-06-14 | 1992-05-19 | Susan Shedlock | Apparatus for suctioning secretions from upper airways |
WO1992021404A1 (en) * | 1991-05-31 | 1992-12-10 | Bechgaard International Research And Development A/S | Nasal dispenser actuated by nose contact |
US5290257A (en) * | 1992-01-02 | 1994-03-01 | Zhong Being Tang | Method and apparatus for de-airing the heart |
US5370631A (en) * | 1992-01-02 | 1994-12-06 | Zhong; Being-Tang | Method and apparatus for de-airing the heart |
US5599304A (en) * | 1994-05-10 | 1997-02-04 | Mount Sinai School Of Medicine Of The City University Of New York | Sinonasal suction apparatus |
US6494204B1 (en) * | 2000-06-23 | 2002-12-17 | Pedro D. Ponce | Nasal medication administering device |
US6820571B2 (en) | 2001-01-26 | 2004-11-23 | George J. Cory | Manually operated animal training device |
US20070289907A1 (en) * | 2006-06-09 | 2007-12-20 | Vanhulzen Chad | System and methods for maintaining an aquarium ecosystem |
US9849062B2 (en) * | 2007-05-16 | 2017-12-26 | Chordate Medical Ab | Vibration device |
US20100274164A1 (en) * | 2007-05-16 | 2010-10-28 | Rhinomed Ab | Vibration device |
US10772792B2 (en) | 2007-05-16 | 2020-09-15 | Chordate Medical Ab | Vibration device |
EP2036527A1 (en) * | 2007-09-13 | 2009-03-18 | Siemens & Co. Heilwasser und Quellenprodukte des Staatsbades Bad Ems GmbH & Co. KG | Nasal spray with non-return valve |
US20090202665A1 (en) * | 2008-02-13 | 2009-08-13 | Bekan Rhinologics Inc. | Nasal irrigation device |
US7862548B2 (en) * | 2008-02-13 | 2011-01-04 | Bekan Rhinologics Inc. | Nasal irrigation device |
US20110166523A1 (en) * | 2008-02-13 | 2011-07-07 | Javer Amin R | Nasal irrigation device |
US9486381B2 (en) | 2011-12-16 | 2016-11-08 | Chordate Medical Ab | ALS treatment |
US9895279B2 (en) * | 2011-12-16 | 2018-02-20 | Chordate Medical Ab | Stimulation of hypothalamus |
US9451889B2 (en) | 2011-12-16 | 2016-09-27 | Chordate Medical Ab | Pressure sensing system and method |
US12042465B2 (en) | 2011-12-16 | 2024-07-23 | Chordate Medical Ab | Treatment of headache disorders |
US20130158450A1 (en) * | 2011-12-16 | 2013-06-20 | Chordate Medical Ag | Treatment of headache disorders |
US9579247B2 (en) * | 2011-12-16 | 2017-02-28 | Chordate Medical Ab | Treatment of headache disorders |
US9782320B2 (en) * | 2011-12-16 | 2017-10-10 | Chordate Medical Ab | Double stimulation |
US20130158448A1 (en) * | 2011-12-16 | 2013-06-20 | Chordate Medical Ag | Stimulation of hypothalamus |
US11452666B2 (en) | 2011-12-16 | 2022-09-27 | Chordate Medical Ab | Treatment of headache disorders |
US9198618B2 (en) | 2011-12-16 | 2015-12-01 | Chordate Medical Ab | Pressure sensing system and method |
US10758446B2 (en) | 2011-12-16 | 2020-09-01 | Chordate Medical Ab | Treatment of headache disorders |
US20130158449A1 (en) * | 2011-12-16 | 2013-06-20 | Chordate Medical Ag | Double stimulation |
US9872814B2 (en) | 2012-03-20 | 2018-01-23 | Chordate Medical Ag | Vibration pattern for vibration stimulation |
US9474684B2 (en) | 2012-03-20 | 2016-10-25 | Chordate Medical Ab | Electroactive vibration method |
US11285072B2 (en) * | 2017-03-28 | 2022-03-29 | Abilion Medical Systems Ab | Devices, systems and methods for mechanical tissue stimulation |
US20220241140A1 (en) * | 2017-03-28 | 2022-08-04 | Abilion Medical Systems Ab | Devices, systems and methods for mechanical tissue stimulation |
US11806307B2 (en) * | 2017-03-28 | 2023-11-07 | Abilion Medical Systems Ab | Devices, systems and methods for mechanical tissue stimulation |
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