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UA88018C2 - Ингибиторы калиевого канала - Google Patents

Ингибиторы калиевого канала

Info

Publication number
UA88018C2
UA88018C2 UAA200702125A UAA200702125A UA88018C2 UA 88018 C2 UA88018 C2 UA 88018C2 UA A200702125 A UAA200702125 A UA A200702125A UA A200702125 A UAA200702125 A UA A200702125A UA 88018 C2 UA88018 C2 UA 88018C2
Authority
UA
Ukraine
Prior art keywords
potassium channel
channel inhibitors
inhibitors
compounds
useful
Prior art date
Application number
UAA200702125A
Other languages
English (en)
Ukrainian (uk)
Inventor
Марк Т. БИЛОДО
Чжицай У
Джон Хартнетт
Original Assignee
Мерк Энд Ко., Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мерк Энд Ко., Инк. filed Critical Мерк Энд Ко., Инк.
Publication of UA88018C2 publication Critical patent/UA88018C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Данное изобретение касается соединений, которые имеют структуру формулы (І) и применяются как ингибиторы калиевого канала для лечения сердечных аритмий.
UAA200702125A 2004-07-29 2005-07-25 Ингибиторы калиевого канала UA88018C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59218104P 2004-07-29 2004-07-29

Publications (1)

Publication Number Publication Date
UA88018C2 true UA88018C2 (ru) 2009-09-10

Family

ID=35613661

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200702125A UA88018C2 (ru) 2004-07-29 2005-07-25 Ингибиторы калиевого канала

Country Status (15)

Country Link
KR (1) KR20070043985A (ru)
AR (1) AR049847A1 (ru)
BR (1) BRPI0513793A (ru)
CR (1) CR8876A (ru)
EC (1) ECSP077208A (ru)
IL (1) IL180846A0 (ru)
MA (1) MA28980B1 (ru)
MX (1) MX2007001188A (ru)
NO (1) NO20071107L (ru)
PE (1) PE20060382A1 (ru)
RU (1) RU2344134C2 (ru)
TW (1) TW200607493A (ru)
UA (1) UA88018C2 (ru)
WO (1) WO2006028590A1 (ru)
ZA (1) ZA200700477B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2408440B1 (en) * 2009-03-18 2016-05-11 Medicure International Inc. Transdermal pharmaceutical preparation and administration of tirofiban
CA2876359C (en) 2012-06-11 2020-01-21 Bristol-Myers Squibb Company Phosphoramidic acid prodrugs of 5-[5-phenyl-4-(pyridin-2-ylmethylamino) quinazolin-2-yl] pyridine-3-sulfonamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE400551T1 (de) * 2002-01-04 2008-07-15 Neurosearch As Kaliumkanal-modulatoren

Also Published As

Publication number Publication date
RU2007107408A (ru) 2008-09-10
CR8876A (es) 2007-08-28
TW200607493A (en) 2006-03-01
MA28980B1 (fr) 2007-11-01
RU2344134C2 (ru) 2009-01-20
KR20070043985A (ko) 2007-04-26
MX2007001188A (es) 2007-03-21
PE20060382A1 (es) 2006-05-15
IL180846A0 (en) 2007-06-03
WO2006028590A1 (en) 2006-03-16
BRPI0513793A (pt) 2008-05-13
ZA200700477B (en) 2009-08-26
NO20071107L (no) 2007-04-19
ECSP077208A (es) 2007-02-28
AR049847A1 (es) 2006-09-06

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