UA19318A - СПОСІБ ОДЕРЖАHHЯ ЛЮДСЬКОЇ МnО2-ДИСМУТАЗИ - Google Patents
СПОСІБ ОДЕРЖАHHЯ ЛЮДСЬКОЇ МnО2-ДИСМУТАЗИInfo
- Publication number
- UA19318A UA19318A UA4355336A UA4355336A UA19318A UA 19318 A UA19318 A UA 19318A UA 4355336 A UA4355336 A UA 4355336A UA 4355336 A UA4355336 A UA 4355336A UA 19318 A UA19318 A UA 19318A
- Authority
- UA
- Ukraine
- Prior art keywords
- dismutase
- obtaining
- human
- mno2
- kdna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/07—Fusion polypeptide containing a localisation/targetting motif containing a mitochondrial localisation signal
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Винахід відноситься до біотехнології і генетичної інженерії, зокрема, до способів одержання людської MnO2-дисмутази для терапевтичних цілей, наприклад, як антизапальний засіб. Спосіб полягає у виділенні з плацентарної або печінкової тканини людини мРНК, отриманні полі (А)+РНК, синтезі двухланцюгової кДНК, конструюванні банку кДНК, виділенні послідовності ДНК і кодуванні Мn2О-дисмутази.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873708306 DE3708306A1 (de) | 1987-03-14 | 1987-03-14 | Humane mangan-superoxiddismutase (hmn-sod) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA19318A true UA19318A (uk) | 1997-12-25 |
Family
ID=6323067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA4355336A UA19318A (uk) | 1987-03-14 | 1988-03-14 | СПОСІБ ОДЕРЖАHHЯ ЛЮДСЬКОЇ МnО2-ДИСМУТАЗИ |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE3708306A1 (uk) |
| SU (1) | SU1741610A3 (uk) |
| UA (1) | UA19318A (uk) |
| ZA (1) | ZA881743B (uk) |
-
1987
- 1987-03-14 DE DE19873708306 patent/DE3708306A1/de not_active Withdrawn
-
1988
- 1988-03-11 ZA ZA881743A patent/ZA881743B/xx unknown
- 1988-03-14 UA UA4355336A patent/UA19318A/uk unknown
- 1988-03-14 SU SU884355336A patent/SU1741610A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| SU1741610A3 (ru) | 1992-06-15 |
| ZA881743B (en) | 1989-11-29 |
| DE3708306A1 (de) | 1988-09-22 |
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