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UA113749C2 - Композиція для назального застосування з покращеною стабільністю - Google Patents

Композиція для назального застосування з покращеною стабільністю

Info

Publication number
UA113749C2
UA113749C2 UAA201408502A UAA201408502A UA113749C2 UA 113749 C2 UA113749 C2 UA 113749C2 UA A201408502 A UAA201408502 A UA A201408502A UA A201408502 A UAA201408502 A UA A201408502A UA 113749 C2 UA113749 C2 UA 113749C2
Authority
UA
Ukraine
Prior art keywords
composition
improved stability
surgical application
disinfectant
preservative
Prior art date
Application number
UAA201408502A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47665594&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA113749(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of UA113749C2 publication Critical patent/UA113749C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Винахід стосується фармацевтичної композиції з покращеною стабільністю для місцевого застосування для лікування ринітів, причому композиція представлена у вигляді водної композиції і причому композиція містить:а) щонайменше один альфа-симпатоміметик на основі імідазоліну або його фізіологічно прийнятну сіль, причому альфа-симпатоміметик на основі імідазоліну вибирають з ксилометазоліну;б) пантотенол (декспантенол); ів) щонайменше один консервант і/або дезінфекційний засіб, причому консервант і/або дезінфекційний засіб вибирають з хлориду бензалконію;причому значення рН композиції встановлюють і/або підтримують постійним в межах від 5,2 до 5,9.
UAA201408502A 2011-12-30 2012-09-25 Композиція для назального застосування з покращеною стабільністю UA113749C2 (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102011122588 2011-12-30
PCT/EP2012/003995 WO2013097911A1 (de) 2011-12-30 2012-09-25 Zusammensetzung für die nasale applikation mit verbesserter stabilität

Publications (1)

Publication Number Publication Date
UA113749C2 true UA113749C2 (xx) 2017-03-10

Family

ID=47665594

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201408502A UA113749C2 (xx) 2011-12-30 2012-09-25 Композиція для назального застосування з покращеною стабільністю

Country Status (9)

Country Link
EP (3) EP4410369A3 (uk)
DE (2) DE102012005452A1 (uk)
DK (1) DK2766008T3 (uk)
EA (1) EA024618B1 (uk)
ES (1) ES2612652T3 (uk)
GE (1) GEP201706609B (uk)
PL (1) PL2766008T3 (uk)
UA (1) UA113749C2 (uk)
WO (1) WO2013097911A1 (uk)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202012005650U1 (de) 2012-05-14 2013-05-15 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Kombinationstherapeutikum für die Behandlung von Rhinitis
DE202014105553U1 (de) * 2014-08-18 2015-08-20 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Cineolhaltige Zusammensetzung für die nasale Applikation
DE202017104738U1 (de) * 2017-07-31 2018-08-01 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Neue Zusammensetzung für die nasale Applikation
ES2972897T3 (es) * 2017-08-10 2024-06-17 Elixir Ilac Arastirma Ve Gelistirme A S Composiciones descongestionantes nasales que comprenden mentol, dexpantenol e hialuronato de sodio
EP3827818A1 (en) * 2019-11-26 2021-06-02 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Ophthalmic composition
EP4404916A1 (en) * 2021-09-22 2024-07-31 JADRAN - GALENSKI LABORATORIJ d.d. An improved pharmaceutical composition for nasal use, preparation, and use thereof
DE102023102070A1 (de) * 2023-01-27 2024-08-01 Lighthouse Pharma GmbH Arzneiformen zur herstellung einer regenerations-nasenspülung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5346886A (en) 1993-11-15 1994-09-13 John Lezdey Topical α-1-antitrypsin, non-aqueous lipid miscible, benzalkonium chloride compositions for treating skin
DE19541919C2 (de) 1995-11-10 1997-11-20 Klosterfrau Mcm Vetrieb Gmbh Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden
DE19549421C2 (de) * 1995-11-10 1999-11-18 Klosterfrau Mcm Vetrieb Gmbh Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden
DE10000612A1 (de) * 2000-01-10 2001-07-19 Min Becker Flüssigkeitspräparate für Augen- und Nasen-Tropfen bzw. Nasenspray ohne Konservierungsmittel
DE10337186A1 (de) 2003-08-13 2005-03-17 Merck Patent Gmbh Wässrige Wirkstoff-Lösung
DE10356248A1 (de) 2003-11-13 2005-06-23 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Pharmazeutische Zusammensetzung zur Behandlung von Rhinitiden
WO2006101882A2 (en) 2005-03-16 2006-09-28 Honeywell International Inc. Medicament delivery formulations, devices and methods
DE102008036725B4 (de) * 2008-08-07 2021-01-28 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Pharmazeutische Zusammensetzung für die nasale Applikation
CN101756964A (zh) 2008-11-20 2010-06-30 北京利乐生制药科技有限公司 一种含有盐酸赛洛唑啉的复方药用鼻腔喷雾剂
CN102361552A (zh) 2009-03-23 2012-02-22 莱拉制药用品私营有限责任公司 用于治疗过敏性眼/鼻疾病的姜黄色素及其代谢物

Also Published As

Publication number Publication date
EA024618B1 (ru) 2016-10-31
DE102012005452A1 (de) 2013-07-04
PL2766008T3 (pl) 2017-05-31
EP2766008A1 (de) 2014-08-20
EP2818163C0 (de) 2024-06-26
DK2766008T3 (en) 2017-02-13
EP2818163B1 (de) 2024-06-26
GEP201706609B (en) 2017-01-25
EP4410369A2 (de) 2024-08-07
EP2766008B1 (de) 2016-11-02
EP2818163A1 (de) 2014-12-31
EP4410369A3 (de) 2024-11-06
EA201491300A1 (ru) 2014-10-30
WO2013097911A1 (de) 2013-07-04
ES2612652T3 (es) 2017-05-18
DE202012002792U1 (de) 2013-01-03

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