TWI855887B - Contact lens product - Google Patents

Abstract

A contact lens product includes a multifocal contact lens and a buffer solution, wherein the contact lens is immersed in the buffer solution. The multifocal contact lens includes a central region and at least one annular region. The annular region surrounds the central region. A diopter of the annular region is different from a diopter of the central region. The annular region closest to a periphery of the multifocal contact lens is a first annular region. When the specific condition is satisfied, the myopia can be prevented, or the progression of the myopia can be controlled.

Description

Contact Lens Products

The present invention relates to a contact lens product, and in particular to a contact lens product that can prevent myopia or control the progression of myopia.

According to data from the World Health Organization (WHO), the prevalence of myopia in various countries around the world ranges from 8% to 62%. However, a survey in Taiwan found that the myopia rate among adolescents and children under the age of 18 is as high as 85%, which is significantly higher than that of other countries. The reason is probably due to the rapid development of 3C electronic devices in recent years, which has caused young children's eyes to receive improper stimulation prematurely and caused excessive eye use. Current research shows that once a child suffers from early-onset myopia, the degree of myopia will increase at a certain rate. The study also pointed out that the younger the age of myopia, the higher the chance of developing high myopia (greater than or equal to 6.0 D) in the future, and patients with high myopia are more likely to develop serious complications such as retinal detachment and glaucoma. Therefore, if we can control and reduce myopia in young children as soon as we detect pseudomyopia, we can effectively avoid pseudomyopia from turning into myopia and prevent the occurrence of high myopia.

The main cause of myopia is the variation of the optical structure of the eyeball, in which the formation of optical imaging is mainly affected by factors such as the cornea, lens and eyeball length. Normal people's eyes can focus the image correctly on the retina to obtain a clear image. Myopic patients may have a blurred image due to the excessive refractive power of the cornea and lens (refractive myopia) or the long axial distance of the eyeball (axial myopia). Myopia symptoms in young children can be divided into myopia and pseudomyopia. Myopia is a condition in which the axial distance of the eyeball is too long and cannot be restored by correction. However, if it is pseudomyopia, it is a temporary myopia symptom caused by excessive force of the ciliary muscle, which is a correctable myopia symptom. There are many clinical methods for correcting pseudomyopia in children, mainly orthokeratology lenses and long-acting mydriatics. However, orthokeratology lenses can easily cause high external pressure and cause discomfort to the wearer. Generally, long-acting mydriatics alone require a higher concentration to correct myopia, but also increase the chance of drug side effects.

One object of the present invention is to provide a contact lens product, which includes a multifocal contact lens and a buffer solution, wherein the multifocal contact lens is soaked in the buffer solution. Thus, the multifocal contact lens can provide physical correction, thereby effectively preventing myopia or controlling the progression of myopia, avoiding discomfort when wearing the lens, and reducing the probability of drug side effects.

According to the present invention, a contact lens product is provided, comprising a multifocal contact lens and a buffer solution. The multifocal contact lens comprises a central area and at least two annular areas. The at least two annular areas are respectively a first annular area and a second annular area. The central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. The refractive power of the second annular area is different from the refractive power of the central area, and the refractive power of the first annular area is different from the refractive power of the central area. The multifocal contact lens is immersed in the buffer solution. The refractive power of the central zone of the multifocal contact lens is PowC, the maximum refractive power of the first annular zone of the multifocal contact lens is PowP1, the diameter of the central zone of the multifocal contact lens is DiC, the outer diameter of the first annular zone of the multifocal contact lens is DiP1, and the outer diameter of the second annular zone of the multifocal contact lens is DiP2, which meets the following conditions: 2 D ＜ |PowC–PowP1|; 0.15 ≤ DiC/DiP1 ≤ 1; and 0.2 ≤ DiC/DiP2 ≤ 1.

Please refer to FIG. 1 , which is a schematic diagram of a contact lens product 100 according to an embodiment of the present invention. The contact lens product 100 includes a multifocal contact lens 110 and a buffer solution 120. The multifocal contact lens 110 is immersed in the buffer solution 120.

Please refer to FIG. 2, which is a schematic plan view of the multifocal contact lens 110 in FIG. 1. The multifocal contact lens 110 includes a central area 111 and a first annular area 112. The first annular area 112 concentrically surrounds the central area 111. The refractive power of the first annular area 112 is different from that of the central area 111. In this way, the multifocal contact lens 110 can be given a multifocal function, so that the peripheral image can be focused in front of the retina, thereby effectively slowing down the axial length growth of the eyeball and preventing the deterioration of myopia. According to an embodiment of the present invention, the refractive power of the central area 111 is fixed.

At least one of the central area 111 and the first annular area 112 of the multifocal contact lens 110 is an aspherical surface, thereby facilitating the first annular area 112 to be designed to have a gradient refractive power.

Please refer to FIG. 1 again. The buffer solution 120 contains a ciliary muscle paralyzer. The weight percentage concentration of the ciliary muscle paralyzer in the buffer solution 120 is ConA, which satisfies the following condition: 0 < ConA ≤ 1%. Thus, the appropriate concentration of the ciliary muscle paralyzer helps relax the ciliary muscle and reduces the probability of drug side effects. Alternatively, it may satisfy the following condition: 0 < ConA ≤ 0.5%. Alternatively, it may satisfy the following condition: 0 < ConA ≤ 0.25%. Alternatively, it may satisfy the following condition: 0 < ConA ≤ 0.1%. Even more, it may satisfy the following condition: 0 < ConA ≤ 0.05%. Or, it may satisfy the following condition: 0 < ConA ≤ 0.01%. The aforementioned buffer solution 120 may be prepared by first preparing a base solution, the base solution may be a solution used for soaking and preserving contact lenses on the market, and then adding a ciliary muscle anesthetic to the base solution to a desired concentration. In addition, no chemical reaction occurs between the base solution and the ciliary muscle anesthetic.

According to the aforementioned contact lens product 100, the composition for preparing the multi-focal contact lens 110 may include a blue light absorbing component. Thus, the multi-focal contact lens 110 can absorb high-energy blue light, thereby reducing the probability of the retina being damaged by blue light. According to an embodiment of the present invention, the blue light absorbing component may be 4-(phenyldiazenyl) phenyl methacrylate.

According to the aforementioned contact lens product 100, the composition for preparing the multifocal contact lens 110 may include a UV (Ultraviolet) absorbing component, and the UV absorbing component may be, but is not limited to, 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl 2-methacrylate, 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate, 4-methacryloxy-2-hydroxybenzophenone, 2-phenylethyl acrylate, 2-phenylethyl acrylate, 2-phenylethyl methacrylate, 2-phenylethyl acrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl methacrylate, 2-phenylethyl The multifocal contact lens 110 can absorb high-energy UV light, thereby reducing the chance of the retina being damaged by UV light. According to one embodiment of the present invention, the UV absorbing component is 2-[2-hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole, and according to another embodiment of the present invention, the UV absorbing component is 2-acrylate 2-(4-benzoyl-3-hydroxyphenoxy)ethyl ester. The aforementioned UV absorbing components can be used simultaneously or individually.

According to the aforementioned contact lens product 100, the material of the multifocal contact lens 110 can be silicone hydrogel, thereby effectively improving the oxygen permeability of the multifocal contact lens 110, and preventing the cornea from causing red eyes, bloodshot eyes, redness and swelling due to lack of oxygen, so as to provide comfort for long-term wearing. The aforementioned silicone hydrogel can be, but is not limited to, contact lens materials classified as Group 5 by the U.S. Food and Drug Administration (USFDA), such as Balafilcon A, Comfilcon A, Efrofilcon A, Enfilcon A, Galyfilcon A, Lotrafilcon A, Lotrafilcon B, Narafilcon A, Narafilcon B, Senofilcon A, Delefilcon A, Somofilcon A, etc.

The composition for preparing the aforementioned silicone hydrogel may include 2-Hydroxyethyl Methacrylate, 3-Methacryloyloxypropyltris(Trimethylsilyloxy) Silane, 2-Hydroxy-2-Methyl-Propiophenone, N-Vinyl-2-Pyrrolidinone, N,N-Dimethyl Acrylamide, Ethylene Glycol Dimethacrylate), (3-(3-Methacryloxy-2-Hydroxypropoxy)Propylbis(Trimethylsiloxy)Methylsilane), Isopropyl Alcohol and Methacrylic Acid.

Preferably, the weight percentages of the components in the composition of the silicone hydrogel are as follows: 0.05% to 25% of hydroxyethyl methacrylate, 0.1% to 40% of methacryloyloxypropyl tris(trimethylsiloxy)silane, 0.01% to 5% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 35% of N-vinyl-2-pyrrolidone, 0.1% to 40% of N,N-dimethylacrylamide, 0.01% to 5% of ethylene glycol dimethacrylate, 0.1% to 30% of (3-methacryloyloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methyl, 0.1% to 30% of isopropyl alcohol, and 0.01% to 5% of methacrylic acid.

More preferably, the weight percentages of the components in the composition of the silicone hydrogel are as follows: 0.1% to 10% of hydroxyethyl methacrylate, 1% to 40% of methacryloyloxypropyl tris(trimethylsiloxy)silane, 0.1% to 2% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 1% to 35% of N-vinyl-2-pyrrolidone, 1% to 20% of N,N-dimethylacrylamide, 0.1% to 2% of ethylene glycol dimethacrylate, 1% to 30% of (3-methacryloyloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methyl, 1% to 20% of isopropyl alcohol, and 0.1% to 2% of methacrylic acid.

The composition for preparing the aforementioned silicone hydrogel may include hydroxyethyl methacrylate, methacryloyloxypropyl tris(trimethylsiloxy)silane, 2-hydroxy-2-methyl-1-phenyl-1-propanone, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, ethylene glycol dimethacrylate, 3-acetoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane ((3-Acryloxy-2-Hydroxypropoxypropyl) Terminated Polydimethylsiloxane) and 1-hexanol.

Preferably, the weight percentages of the components in the composition of the silicone hydrogel are as follows: 0.05% to 25% of hydroxyethyl methacrylate, 0.1% to 40% of methacryloyloxypropyl tris(trimethylsiloxy)silane, 0.01% to 5% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 35% of N-vinyl-2-pyrrolidone, 0.1% to 40% of N,N-dimethylacrylamide, 0.01% to 5% of ethylene glycol dimethacrylate, 0.1% to 40% of 3-acetoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane, and 0.1% to 30% of n-hexanol.

More preferably, the weight percentages of the components in the composition of the silicone hydrogel are as follows: 0.1% to 10% of hydroxyethyl methacrylate, 1% to 40% of methacryloyloxypropyl tris(trimethylsiloxy)silane, 0.1% to 2% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 1% to 35% of N-vinyl-2-pyrrolidone, 1% to 20% of N,N-dimethylacrylamide, 0.1% to 2% of ethylene glycol dimethacrylate, 1% to 40% of 3-acetoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane, and 1% to 30% of n-hexanol.

The composition for preparing the aforementioned silicone hydrogel may include hydroxyethyl methacrylate, methacryloyloxypropyl tris(trimethylsiloxy)silane, 2-hydroxy-2-methyl-1-phenyl-1-propanone, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, dimethylsiloxane modified urethane oligomer (Polysiloxane Macromer), methyl methacrylate (Methyl Methacrylate) and ethanol (Ethanol).

Preferably, the weight percentage of each component in the composition of the silicone hydrogel is as follows: 0.05% to 25% of hydroxyethyl methacrylate, 0.1% to 40% of methacryloxypropyl tris(trimethylsiloxy)silane, 0.01% to 5% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 35% of N-vinyl-2-pyrrolidone, 0.1% to 40% of N,N-dimethylacrylamide, 0.1% to 40% of dimethylsiloxane-modified urethane oligomer, 0.1% to 40% of methyl methacrylate, and 0.1% to 30% of ethanol.

More preferably, the weight percentages of the components in the composition of the silicone hydrogel are as follows: 0.1% to 10% of hydroxyethyl methacrylate, 1% to 40% of methacryloxypropyl tris(trimethylsiloxy)silane, 0.1% to 2% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 1% to 35% of N-vinyl-2-pyrrolidone, 1% to 20% of N,N-dimethylacrylamide, 1% to 40% of dimethylsiloxane-modified urethane oligomer, 1% to 10% of methyl methacrylate, and 1% to 20% of ethanol.

According to an embodiment of the present invention, the composition of the silicone hydrogel may further include a blue light absorbing component or a UV absorbing component. Preferably, the weight percentage of the blue light absorbing component or the UV absorbing component in the composition of the silicone hydrogel is 0.01%~10%. More preferably, the weight percentage of the blue light absorbing component or the UV absorbing component in the composition of the silicone hydrogel is 0.1%~5%.

By adjusting the ratio of each component in the aforementioned silicone hydrogel, the oxygen permeability and hardness of the multifocal contact lens 110 can be effectively increased. In addition, other components can be added to the aforementioned silicone hydrogel composition according to actual needs.

According to the aforementioned contact lens product 100, the material of the multifocal contact lens 110 may be hydrogel, thereby maintaining the multifocal contact lens 110's moist, smooth, soft and comfortable moisture feeling, allowing it to be worn for a long time and avoiding the foreign body sensation when worn. The aforementioned hydrogel may be a contact lens material classified as Group I by the U.S. Food and Drug Administration, i.e., a nonionic polymer with a low water content (less than 50 weight percent), such as materials named Helfilcon A&B, Hioxifilcon B, Mafilcon, Polymacon, Tefilcon, Tetrafilcon A, etc. Alternatively, the hydrogel may be a contact lens material classified as Group II by the U.S. Food and Drug Administration, i.e., a non-ionic polymer with a high water content (greater than 50 weight percent), such as materials named Acofilcon A, Alfafilcon A, Hilafilcon B, Hioxifilcon A, Hioxifilcon B, Hioxifilcon D, Nelfilcon A, Nesofilcon A, Omafilcon A, and Samfilcon A. Alternatively, the hydrogel may be a contact lens material classified as Group III by the U.S. Food and Drug Administration, i.e., an ionic polymer with a low water content (less than 50 weight percent), such as materials named Deltafilcon A. Alternatively, the aforementioned hydrogel may be a Group IV contact lens material approved by the U.S. Food and Drug Administration, i.e., an ionic polymer with a high water content (greater than 50 weight percent), such as materials named Etafilcon A, Focofilcon A, Methafilcon A, Methafilcon B, Ocufilcon A, Ocufilcon B, Ocufilcon C, Ocufilcon D, Ocufilcon E, Phemfilcon A, Vifilcon A, etc.

The composition for preparing the hydrogel may include hydroxyethyl methacrylate, ethylene glycol dimethacrylate, 2-hydroxy-2-methyl-1-phenyl-1-propanone, glycerol, 1,1,1-trimethylol propane trimethacrylate and methacrylic acid.

Preferably, the weight percentages of the components in the composition of the hydrogel are as follows: 10% to 96% of hydroxyethyl methacrylate, 0.01% to 5% of ethylene glycol dimethacrylate, 0.01% to 5% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 30% of glycerol, 0.01% to 5% of trihydroxymethylpropane trimethacrylate, and 0.01% to 5% of methacrylic acid.

More preferably, the weight percentages of the components in the aforementioned hydrogel composition are as follows: 40% to 96% of hydroxyethyl methacrylate, 0.1% to 2% of ethylene glycol dimethacrylate, 0.1% to 2% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 20% of glycerol, 0.1% to 20% of trihydroxymethylpropane trimethacrylate, and 0.1% to 2% of methacrylic acid.

The composition for preparing the hydrogel may include hydroxyethyl methacrylate, ethylene glycol dimethacrylate, 2-hydroxy-2-methyl-1-phenyl-1-propanone, glycerol, trihydroxymethylpropane trimethacrylate and 2-methyl-2-acrylate-2,3-dihydroxypropyl ester (Glycerol Monomethacrylate).

Preferably, the weight percentages of the components in the composition of the hydrogel are as follows: 10% to 94.87% of hydroxyethyl methacrylate, 0.01% to 5% of ethylene glycol dimethacrylate, 0.01% to 5% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 30% of glycerol, 0.01% to 5% of trihydroxymethylpropane trimethacrylate, and 5% to 60% of 2-methyl-2-acrylate-2,3-dihydroxypropyl ester.

More preferably, the weight percentages of the components in the composition of the hydrogel are as follows: 40% to 79.6% of hydroxyethyl methacrylate, 0.1% to 2% of ethylene glycol dimethacrylate, 0.1% to 2% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 20% of glycerol, 0.1% to 20% of trihydroxymethylpropane trimethacrylate, and 20% to 50% of 2-methyl-2-acrylate-2,3-dihydroxypropyl ester.

The composition for preparing the hydrogel may include hydroxyethyl methacrylate, ethylene glycol dimethacrylate, 2-hydroxy-2-methyl-1-phenyl-1-propanone, glycerol and N-vinyl-2-pyrrolidone.

Preferably, the weight percentages of the components in the aforementioned hydrogel composition are as follows: 10% to 96% of hydroxyethyl methacrylate, 0.01% to 5% of ethylene glycol dimethacrylate, 0.01% to 5% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 0.1% to 30% of glycerol, and 0.1% to 25% of N-vinyl-2-pyrrolidone.

More preferably, the weight percentages of the components in the aforementioned hydrogel composition are as follows: 40% to 96% of hydroxyethyl methacrylate, 0.1% to 2% of ethylene glycol dimethacrylate, 0.1% to 2% of 2-hydroxy-2-methyl-1-phenyl-1-propanone, 1% to 20% of glycerol, and 0.1% to 10% of N-vinyl-2-pyrrolidone.

According to an embodiment of the present invention, the composition of the hydrogel may further include a blue light absorbing component or a UV absorbing component. Preferably, the weight percentage of the blue light absorbing component or the UV absorbing component in the composition of the hydrogel is 0.01% to 10%. More preferably, the weight percentage of the blue light absorbing component or the UV absorbing component in the composition of the hydrogel is 0.1% to 5%.

By adjusting the ratio of each component in the aforementioned hydrogel, the water content and softness of the multifocal contact lens 110 can be effectively increased. In addition, the aforementioned hydrogel composition can be added with other components according to actual needs. The monomers used in the hydrogel composition and the silicone hydrogel composition, such as hydroxyethyl methacrylate, methacrylic acid, 2-methyl-2-acrylate-2,3-dihydroxypropyl ester, N-vinyl-2-pyrrolidone, methacryloxypropyl tris(trimethylsiloxyalkyl)silane, N,N-dimethylacrylamide, (3-methacryloxy-2-hydroxypropoxy)propyl bis(trimethylsiloxy)methyl, 3-acetoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane, methyl methacrylate, etc., can also be replaced with each other according to actual needs.

Please refer to FIG. 2 again. The diameter of the center area 111 of the multifocal contact lens 110 is DiC, which can meet the following conditions: 4 mm ≤ DiC ≤ 10 mm. In this way, the center area 111 can be flexibly adjusted according to the pupil size under different physiological conditions to improve the accuracy of myopia correction, so that the image can be presented completely and clearly on the retina. Preferably, it can meet the following conditions: 5 mm ≤ DiC ≤ 9 mm.

The outer diameter of the first annular zone 112 of the multifocal contact lens 110 is DiP1, which can meet the following conditions: 6 mm ≤ DiP1 ≤ 17 mm. Thus, it can be flexibly adjusted according to the size of the palpebral fissure to provide the multifocal contact lens 110 with an appropriate fit and increase the stability of the multifocal contact lens 110 after wearing. Preferably, it can meet the following conditions: 7 mm ≤ DiP1 ≤ 15 mm.

The diameter of the central area 111 of the multifocal contact lens 110 is DiC, and the outer diameter of the first annular area 112 of the multifocal contact lens 110 is DiP1, which can meet the following condition: 0.15 ≤ DiC/DiP1 < 1. Thus, the appropriate size of DiC/DiP1 is conducive to designing an appropriate multifocal contact lens 110 according to the physiological condition of the individual eyeball, and further conducive to correcting myopia.

The refractive power of the central area 111 of the multifocal contact lens 110 is PowC, which can meet the following conditions: -6.00 ≤ PowC ≤ -0.25. In this way, the appropriate degree of myopia correction can be provided according to the needs of the user, thereby providing a clear image.

The maximum diopter of the first annular zone 112 of the multifocal contact lens 110 is PowP1, which can meet the following condition: -5.50 ≤ PowP1 ≤ -0.50. Thus, the maximum diopter of the first annular zone 112 can be appropriately designed, which is beneficial for correcting myopia.

The refractive power of the central area 111 of the multifocal contact lens 110 is PowC, and the maximum refractive power of the first annular area 112 of the multifocal contact lens 110 is PowP1, which can meet the following conditions: |PowC – PowP1| ≤ 3. This is beneficial for correcting myopia, slowing down the increase in the refractive power of the first annular area 112, and avoiding discomfort caused by excessive increase in the maximum refractive power. Alternatively, it can meet the following conditions: |PowC – PowP1| ≤ 2. Alternatively, it can meet the following conditions: |PowC – PowP1| ≤ 1.5. Alternatively, it can meet the following conditions: |PowC – PowP1| ≤ 1. Alternatively, it may satisfy the following condition: |PowC – PowP1| ≤ 0.5. Even more alternatively, it may satisfy the following condition: |PowC – PowP1| ≤ 0.25.

Please refer to FIG. 3, which is a schematic plan view of a multifocal contact lens 210 according to another embodiment of the present invention. The multifocal contact lens 210 comprises a central area 211, a first annular area 212 and a second annular area 213. The central area 211, the second annular area 213 and the first annular area 212 are sequentially connected from the center to the periphery and have the same center. The diameter of the central area 211 is DiC, the outer diameter of the first annular area 212 is DiP1, and the outer diameter of the second annular area 213 is DiP2. The refractive power of the second annular area 213 is different from the refractive power of the central area 211, and the refractive power of the first annular area 212 is different from the refractive power of the central area 211. In this way, the multi-focal contact lens 210 can be endowed with a multi-focal function, so that the peripheral image can be focused in front of the retina, thereby effectively slowing down the growth of the eyeball's axial length and preventing the deterioration of myopia. According to an embodiment of the present invention, the diopter of the central area 211 is fixed.

At least one of the central area 211, the first annular area 212 and the second annular area 213 may be an aspherical surface, thereby facilitating the first annular area 212 and/or the second annular area 213 to be designed to have a gradient refractive power.

The outer diameter of the second annular zone 213 of the multifocal contact lens 210 is DiP2, which can meet the following conditions: 5 mm ≤ DiP2 ≤ 13 mm. In this way, the increase in diopter can be effectively alleviated. Preferably, it can meet the following conditions: 6 mm ≤ DiP2 ≤ 12 mm.

The diameter of the central area 211 of the multifocal contact lens 210 is DiC, and the outer diameter of the second annular area 213 of the multifocal contact lens 210 is DiP2, which can meet the following condition: 0.2 ≤ DiC/DiP2 < 1. In this way, the increase in the diopter of the second annular area 213 can be effectively slowed down, reducing the discomfort caused by the excessive increase in diopter.

Other properties of the multifocal contact lens 210 may be the same as those of the multifocal contact lens 110 and will not be described in detail here.

Please refer to FIG. 4, which is a schematic plan view of a multi-focal contact lens 310 according to another embodiment of the present invention. The multi-focal contact lens 310 includes a central area 311, a first annular area 312, a second annular area 313, and a third annular area 314. The central area 311, the third annular area 314, the second annular area 313, and the first annular area 312 are sequentially connected from the center to the periphery and have the same center. The diameter of the first annular zone 312 is DiC, the outer diameter of the first annular zone 312 is DiP1, the outer diameter of the second annular zone 313 is DiP2, and the outer diameter of the third annular zone 314 is DiP3, wherein the diopter of the third annular zone 314 is different from the diopter of the central zone 311, the diopter of the second annular zone 313 is different from the diopter of the central zone 311, and the diopter of the first annular zone 312 is different from the diopter of the central zone 311. In this way, the multi-focal contact lens 310 can be given a multi-focal function, so that the peripheral image can be focused in front of the retina, thereby effectively slowing down the axial length growth of the eyeball and avoiding the deterioration of myopia. According to an embodiment of the present invention, the diopter of the central zone 311 is fixed.

As can be seen from FIGS. 2 to 4, the multifocal contact lens according to the present invention can be concentrically provided with at least one annular zone (first annular zone (112, 212, 312), second annular zone (213, 313), third annular zone (314)) outside the central zone (111, 211, 311), and the number of annular zones and the configuration of their refractive powers can be flexibly adjusted to meet the physiological conditions of the individual eyeball, thereby improving the effect of correcting myopia and effectively preventing myopia or controlling the progression of myopia.

According to the present invention, a contact lens product is also provided, including a multifocal contact lens, wherein the composition for preparing the multifocal contact lens includes a blue light absorbing component. Thus, the multifocal contact lens can absorb high-energy blue light, thereby reducing the probability of the retina being damaged by blue light. For the blue light absorbing component, the material of the multifocal contact lens, and other details of the multifocal contact lens, please refer to the contents of Figures 1 to 4 above, and will not be repeated here.

<First embodiment>

The multifocal contact lens of the first embodiment comprises a central area and a first annular area, wherein the first annular area concentrically surrounds the central area, and at least one of the central area and the first annular area is aspherical. For the structure of the multifocal contact lens of the first embodiment, please refer to FIG. 2 .

In the multifocal contact lens of the first embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the diopter of the central area is PowC, and the maximum diopter of the first annular area is PowP1. For the values of DiC, DiP1, DiC/DiP1, PowC, PowP1, and |PowC – PowP1| of the first embodiment, please refer to Table 1. Table 1. First embodiment DiC (mm) 5.00 PowC (D) -0.25 DiP1 (mm) 13.00 PowP1 (D) 0.25 DiC/DiP1 0.38 |PowC – PowP1| (D) 0.50

Please refer to Table 2 and Figure 5 at the same time. Table 2 lists the radius of the multifocal contact lens of the first embodiment and its corresponding diopter. Figure 5 is a relationship diagram between the radius and diopter of the multifocal contact lens of the first embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 2 and Figure 5 that the diopter of the central area is fixed, and the diopter of the first annular area is different from the diopter of the central area. Specifically, the diopter of the first annular area is greater than that of the central area, and the diopter of the first annular area increases as it is farther away from the central area. Table 2: First embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -6.50 0.25 0.50 -0.25 -6.00 0.19 1.00 -0.25 -5.50 0.13 1.50 -0.25 -5.00 0.06 2.00 -0.25 -4.50 0.00 2.50 -0.25 -4.00 -0.06 3.00 -0.19 -3.50 -0.13 3.50 -0.13 -3.00 -0.19 4.00 -0.06 -2.50 -0.25 4.50 0.00 -2.00 -0.25 5.00 0.06 -1.50 -0.25 5.50 0.13 -1.00 -0.25 6.00 0.19 -0.50 -0.25 6.50 0.25 0.00 -0.25

The material of the multifocal contact lens of the first embodiment is hydrogel. Please refer to Table 3 for the composition of the hydrogel of the first embodiment. Table 3 Element Content (wt%) Hydroxyethyl Methacrylate 82 2-[2-Hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole 1.2 Ethylene glycol dimethacrylate 0.4 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.5 glycerin 13.5 Trihydroxymethylpropane trimethacrylate 0.2 Methacrylic acid 2.2

As shown in Table 3, by adding 2-[2-hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole, the multi-focal contact lens of the first embodiment can absorb UV light.

<Second embodiment>

The multifocal contact lens of the second embodiment comprises a central area, a first annular area and a second annular area. The central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. At least one of the central area, the second annular area and the first annular area is an aspherical surface. The structure of the multifocal contact lens of the second embodiment can be referred to FIG. 3 .

In the multifocal contact lens of the second embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the outer diameter of the second annular area is DiP2, the diopter of the central area is PowC, the maximum diopter of the first annular area is PowP1, and the maximum diopter of the second annular area is PowP2. For the values of DiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, and |PowC – PowP1| of the second embodiment, please refer to Table 4. Table 4. Second embodiment DiC (mm) 5.00 PowC (D) -0.50 DiP1 (mm) 16.00 PowP1 (D) 0.50 DiP2 (mm) 13.00 PowP2 (D) 0.50 DiC/DiP1 0.31 |PowC – PowP1| (D) 1.00 DiC/DiP2 0.38

Please refer to Table 5 and Figure 6 at the same time. Table 5 lists the radius of the multifocal contact lens of the second embodiment and its corresponding diopter. Figure 6 is a relationship diagram between the radius and diopter of the multifocal contact lens of the second embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 5 and Figure 6 that the diopter of the central area is fixed, the diopter of the second annular area is different from the diopter of the central area, and the diopter of the first annular area is different from the diopter of the central area. Specifically, the diopter of the second annular area is greater than the diopter of the central area, and the diopter of the second annular area increases as it is farther away from the central area, and the diopter of the first annular area is greater than the diopter of the central area, and the diopter of the first annular area is fixed. Table 5. Second embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -8.00 0.50 0.50 -0.50 -7.50 0.50 1.00 -0.50 -7.00 0.50 1.50 -0.50 -6.50 0.50 2.00 -0.50 -6.00 0.38 2.50 -0.50 -5.50 0.25 3.00 -0.38 -5.00 0.13 3.50 -0.25 -4.50 0.00 4.00 -0.13 -4.00 -0.13 4.50 0.00 -3.50 -0.25 5.00 0.13 -3.00 -0.38 5.50 0.25 -2.50 -0.50 6.00 0.38 -2.00 -0.50 6.50 0.50 -1.50 -0.50 7.00 0.50 -1.00 -0.50 7.50 0.50 -0.50 -0.50 8.00 0.50 0.00 -0.50

The material of the multifocal contact lens of the second embodiment is hydrogel. Please refer to Table 6A for the composition of the hydrogel of the second embodiment. Table VIA Element Content (wt%) Hydroxyethyl Methacrylate 44.8 2-[2-Hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole 1.2 Ethylene glycol dimethacrylate 0.6 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 glycerin 10.5 Trihydroxymethylpropane trimethacrylate 0.3 2-Methyl-2-acrylate-2,3-dihydroxypropyl ester 42

As shown in Table 6A, by adding 2-[2-hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole, the multi-focal contact lens of the second embodiment can absorb UV light.

Please refer to FIG. 7, which is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the second embodiment and the multifocal contact lenses of the first comparative example. The difference between the first comparative example and the second embodiment is that the first comparative example does not add a UV absorbing component. Specifically, the first comparative example replaces 2-[2-hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole with hydroxyethyl methacrylate. From FIG. 7, it can be inferred that the multifocal contact lenses of the first comparative example and the second embodiment have a wavelength of 100 nm and a transmittance of 100 nm. The blocking rate of the multifocal contact lenses of the first comparative example and the second embodiment for UV-A (UV light with a wavelength range of 316nm~380nm) is calculated as follows: (1-average transmittance of wavelength 316~380nm)*100%, and the blocking rate of the multifocal contact lenses of the first comparative example and the second embodiment for UV-B (UV light with a wavelength range of 280nm~315nm) is calculated as follows: (1-average transmittance of wavelength 280nm~315nm)×100%, and the results are listed in Table 6B. Table VIB First comparison example Second Embodiment UV-A blocking rate (%) (316 nm ~380 nm) 5.92 73.19 UV-B blocking rate (%) (280 nm ~315 nm) 7.91 96.36

As shown in Table 6B, compared with the first comparative example, the blocking rate of UV-A and UV-B of the second embodiment are much greater than those of the first comparative example. In other words, the multifocal contact lenses of the second embodiment can effectively absorb UV light, thereby reducing the probability of the retina being damaged by UV light.

<Third Embodiment>

The multifocal contact lens of the third embodiment comprises a central area, a first annular area and a second annular area. The central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. At least one of the central area, the second annular area and the first annular area is an aspherical surface. The structure of the multifocal contact lens of the third embodiment can be referred to FIG. 3 .

In the multifocal contact lens of the third embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the outer diameter of the second annular area is DiP2, the diopter of the central area is PowC, the maximum diopter of the first annular area is PowP1, and the maximum diopter of the second annular area is PowP2. For the values of DiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, and |PowC – PowP1| of the third embodiment, please refer to Table 7. Table 7. Third embodiment DiC (mm) 4.00 PowC (D) -1.00 DiP1 (mm) 15.00 PowP1 (D) 0.25 DiP2 (mm) 6.00 PowP2 (D) -0.50 DiC/DiP1 0.27 |PowC – PowP1| (D) 1.25 DiC/DiP2 0.67

Please refer to Table 8 and Figure 8. Table 8 lists the radius of the multifocal contact lens of the third embodiment and its corresponding diopter. Figure 8 is a relationship diagram between the radius and diopter of the multifocal contact lens of the third embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 8 and Figure 8 that the diopter of the central area is fixed, and the diopter of the second annular area is The diopter of the first annular zone is different from the diopter of the central zone, and the diopter of the first annular zone is different from the diopter of the central zone. Specifically, the diopter of the second annular zone is greater than that of the central zone, and the diopter of the second annular zone increases as it moves away from the central zone, and the diopter of the first annular zone is greater than that of the central zone, and the diopter of the first annular zone increases as it moves away from the central zone. Table 8. Third embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -7.50 0.25 0.50 -1.00 -7.00 0.17 1.00 -1.00 -6.50 0.08 1.50 -1.00 -6.00 0.00 2.00 -1.00 -5.50 -0.08 2.50 -0.75 -5.00 -0.17 3.00 -0.50 -4.50 -0.25 3.50 -0.42 -4.00 -0.33 4.00 -0.33 -3.50 -0.42 4.50 -0.25 -3.00 -0.50 5.00 -0.17 -2.50 -0.75 5.50 -0.08 -2.00 -1.00 6.00 0.00 -1.50 -1.00 6.50 0.08 -1.00 -1.00 7.00 0.17 -0.50 -1.00 7.50 0.25 0.00 -1.00

The material of the multifocal contact lens of the third embodiment is hydrogel. Please refer to Table 9 for the composition of the hydrogel of the third embodiment. Table 9 Element Content (wt%) Hydroxyethyl Methacrylate 91 2-[2-Hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole 1 Ethylene glycol dimethacrylate 0.6 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 glycerin 6.3 N-vinyl-2-pyrrolidone 0.5

As shown in Table 9, by adding 2-[2-hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole, the multi-focal contact lens of the third embodiment can absorb UV light.

<Fourth embodiment>

The multifocal contact lens of the fourth embodiment comprises a central area and a first annular area, wherein the first annular area concentrically surrounds the central area, and at least one of the central area and the first annular area is aspherical. For the structure of the multifocal contact lens of the fourth embodiment, please refer to FIG. 2 .

In the multifocal contact lens of the fourth embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the refractive power of the central area is PowC, and the maximum refractive power of the first annular area is PowP1. For the values of DiC, DiP1, DiC/DiP1, PowC, PowP1, and |PowC – PowP1| of the fourth embodiment, please refer to Table 10. Table 10: Fourth Embodiment DiC (mm) 7.00 PowC (D) -1.50 DiP1 (mm) 14.00 PowP1 (D) -1.00 DiC/DiP1 0.50 |PowC – PowP1| (D) 0.50

Please refer to Table 11 and Figure 9 at the same time. Table 11 lists the radius of the multifocal contact lens of the fourth embodiment and its corresponding diopter (negative value only indicates the radius distance in the opposite direction). Figure 9 is a relationship diagram between the radius and diopter of the multifocal contact lens of the fourth embodiment. It can be seen from Table 11 and Figure 9 that the diopter of the central area is fixed, and the diopter of the first annular area is different from the diopter of the central area. Specifically, the diopter of the first annular area is greater than that of the central area, and the diopter of the first annular area increases as it is farther away from the central area. Table 11: Fourth embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -7.00 -1.00 0.50 -1.50 -6.50 -1.07 1.00 -1.50 -6.00 -1.14 1.50 -1.50 -5.50 -1.21 2.00 -1.50 -5.00 -1.29 2.50 -1.50 -4.50 -1.36 3.00 -1.50 -4.00 -1.43 3.50 -1.50 -3.50 -1.50 4.00 -1.43 -3.00 -1.50 4.50 -1.36 -2.50 -1.50 5.00 -1.29 -2.00 -1.50 5.50 -1.21 -1.50 -1.50 6.00 -1.14 -1.00 -1.50 6.50 -1.07 -0.50 -1.50 7.00 -1.00 0.00 -1.50

The material of the multifocal contact lens of the fourth embodiment is hydrogel. Please refer to Table 12A for the composition of the hydrogel of the fourth embodiment. Table 12A Element Content (wt%) Hydroxyethyl Methacrylate 82 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate 1 Ethylene glycol dimethacrylate 0.4 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 glycerin 13.6 Trihydroxymethylpropane trimethacrylate 0.2 Methacrylic acid 2.2

As shown in Table 12A, by adding 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate, the multifocal contact lens of the fourth embodiment can absorb UV light.

Please refer to FIG. 10, which is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the fourth embodiment and the second comparative example. The difference between the second comparative example and the fourth embodiment is that the second comparative example does not add a UV absorbing component. Specifically, the second comparative example replaces 2-(4-benzoyl-3-hydroxyphenoxy)ethyl 2-acrylate with hydroxyethyl methacrylate. From FIG. 10, it can be inferred that the multifocal contact lenses of the second comparative example and the fourth embodiment have a UV absorption component of 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate. -A (UV light with a wavelength range of 316nm~380nm), the calculation method is as follows: (1-average transmittance of wavelength 316~380nm)*100%, and the blocking rate of the multifocal contact lenses of the second comparative example and the fourth embodiment for UV-B (UV light with a wavelength range of 280nm~315nm), the calculation method is as follows: (1-average transmittance of wavelength 280nm~315nm)×100%, and the results are listed in Table 12B. Table 12B Second comparison example Fourth embodiment UV-A blocking rate (%) (316 nm ~380 nm) 6.44 79.32 UV-B blocking rate (%) (280 nm ~315 nm) 8.76 98.39

As shown in Table 12B, compared with the second comparative example, the UV-A blocking rate and UV-B blocking rate of the fourth embodiment are much greater than those of the second comparative example. In other words, the multifocal contact lenses of the fourth embodiment can effectively absorb UV light, thereby reducing the probability of the retina being damaged by UV light.

<Fifth Embodiment>

The multifocal contact lens of the fifth embodiment comprises a central area, a first annular area and a second annular area. The central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. At least one of the central area, the second annular area and the first annular area is an aspherical surface. The structure of the multifocal contact lens of the fifth embodiment can be referred to FIG. 3 .

In the multifocal contact lens of the fifth embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the outer diameter of the second annular area is DiP2, the diopter of the central area is PowC, the maximum diopter of the first annular area is PowP1, and the maximum diopter of the second annular area is PowP2. For the values of DiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, and |PowC – PowP1| of the fifth embodiment, please refer to Table 13. Table 13. Fifth embodiment DiC (mm) 8.00 PowC (D) -2.00 DiP1 (mm) 15.00 PowP1 (D) 0 DiP2 (mm) 11.00 PowP2 (D) 0 DiC/DiP1 0.53 |PowC – PowP1| (D) 2.00 DiC/DiP2 0.73

Please refer to Table 14 and Figure 11 at the same time. Table 14 lists the radius of the multifocal contact lens of the fifth embodiment and its corresponding diopter. Figure 11 is a relationship diagram between the radius and diopter of the multifocal contact lens of the fifth embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 14 and Figure 11 that the diopter of the central area is fixed, the diopter of the second annular area is different from the diopter of the central area, and the diopter of the first annular area is different from the diopter of the central area. Specifically, the diopter of the second annular area is greater than the diopter of the central area, and the diopter of the second annular area increases as it is farther away from the central area, and the diopter of the first annular area is greater than the diopter of the central area, and the diopter of the first annular area is fixed. Table 14. Fifth embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -7.50 0.00 0.50 -2.00 -7.00 0.00 1.00 -2.00 -6.50 0.00 1.50 -2.00 -6.00 0.00 2.00 -2.00 -5.50 0.00 2.50 -2.00 -5.00 -0.67 3.00 -2.00 -4.50 -1.33 3.50 -2.00 -4.00 -2.00 4.00 -2.00 -3.50 -2.00 4.50 -1.33 -3.00 -2.00 5.00 -0.67 -2.50 -2.00 5.50 0.00 -2.00 -2.00 6.00 0.00 -1.50 -2.00 6.50 0.00 -1.00 -2.00 7.00 0.00 -0.50 -2.00 7.50 0.00 0.00 -2.00

The material of the multifocal contact lens of the fifth embodiment is hydrogel. Please refer to Table 15 for the composition of the hydrogel prepared in the fifth embodiment. Table 15 Element Content (wt%) Hydroxyethyl Methacrylate 45 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate 0.9 Ethylene glycol dimethacrylate 0.6 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 glycerin 10.6 Trihydroxymethylpropane trimethacrylate 0.3 2-Methyl-2-acrylate-2,3-dihydroxypropyl ester 42

It can be seen from Table 15 that by adding 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate, the multifocal contact lens of the fifth embodiment can absorb UV light.

<Sixth embodiment>

The multifocal contact lens of the sixth embodiment comprises a central area and a first annular area, wherein the first annular area concentrically surrounds the central area, and at least one of the central area and the first annular area is an aspherical surface. For the structure of the multifocal contact lens of the sixth embodiment, please refer to FIG. 2 .

In the multifocal contact lens of the sixth embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the refractive power of the central area is PowC, and the maximum refractive power of the first annular area is PowP1. For the values of DiC, DiP1, DiC/DiP1, PowC, PowP1, and |PowC – PowP1| of the sixth embodiment, please refer to Table 16. Table 16. Sixth Embodiment DiC (mm) 9.00 PowC (D) -2.50 DiP1 (mm) 14.00 PowP1 (D) -2.25 DiC/DiP1 0.64 |PowC – PowP1| (D) 0.25

Please refer to Table 17 and Figure 12 at the same time. Table 17 lists the radius of the multifocal contact lens of the sixth embodiment and its corresponding diopter. Figure 12 is a relationship diagram between the radius and diopter of the multifocal contact lens of the sixth embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 17 and Figure 12 that the diopter of the central area is fixed, and the diopter of the first annular area is different from the diopter of the central area. Specifically, the diopter of the first annular area is greater than that of the central area, and the diopter of the first annular area increases as it is farther away from the central area. Table 17. Sixth Embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -7.00 -2.25 0.50 -2.50 -6.50 -2.30 1.00 -2.50 -6.00 -2.35 1.50 -2.50 -5.50 -2.40 2.00 -2.50 -5.00 -2.45 2.50 -2.50 -4.50 -2.50 3.00 -2.50 -4.00 -2.50 3.50 -2.50 -3.50 -2.50 4.00 -2.50 -3.00 -2.50 4.50 -2.50 -2.50 -2.50 5.00 -2.45 -2.00 -2.50 5.50 -2.40 -1.50 -2.50 6.00 -2.35 -1.00 -2.50 6.50 -2.30 -0.50 -2.50 7.00 -2.25 0.00 -2.50

The material of the multifocal contact lens of the sixth embodiment is hydrogel. Please refer to Table 18 for the composition of the hydrogel prepared in the sixth embodiment. Table 18 Element Content (wt%) Hydroxyethyl Methacrylate 90.4 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate 1.2 Ethylene glycol dimethacrylate 0.6 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.7 glycerin 6.3 N-vinyl-2-pyrrolidone 0.8

It can be seen from Table 18 that by adding 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate, the multifocal contact lens of the sixth embodiment can absorb UV light.

<Seventh Embodiment>

The multifocal contact lens of the seventh embodiment comprises a central area, a first annular area and a second annular area. The central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. At least one of the central area, the second annular area and the first annular area is an aspherical surface. The structure of the multifocal contact lens of the seventh embodiment can be referred to FIG. 3 .

In the multifocal contact lens of the seventh embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the outer diameter of the second annular area is DiP2, the refractive power of the central area is PowC, the maximum refractive power of the first annular area is PowP1, and the maximum refractive power of the second annular area is PowP2. For the values of DiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, and |PowC – PowP1| of the seventh embodiment, please refer to Table 19. Table 19. Seventh Embodiment DiC (mm) 4.00 PowC (D) -3.00 DiP1 (mm) 15.00 PowP1 (D) -1.00 DiP2 (mm) 8.00 PowP2 (D) -2.00 DiC/DiP1 0.27 |PowC – PowP1| (D) 2.00 DiC/DiP2 0.50

Please refer to Table 20 and FIG. 13. Table 20 lists the radius of the multifocal contact lens of the seventh embodiment and its corresponding diopter. FIG. 13 is a relationship diagram between the radius and diopter of the multifocal contact lens of the seventh embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 20 and FIG. 13 that the diopter of the central area is fixed, and the diopter of the second ring is fixed. The refractive power of the second annular zone is different from that of the central zone, and the refractive power of the first annular zone is different from that of the central zone. Specifically, the refractive power of the second annular zone is greater than that of the central zone, and the refractive power of the second annular zone increases as it moves away from the central zone, and the refractive power of the first annular zone is greater than that of the central zone, and the refractive power of the first annular zone increases as it moves away from the central zone. Table 20, Seventh Embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -7.50 -1.00 0.50 -3.00 -7.00 -1.14 1.00 -3.00 -6.50 -1.29 1.50 -3.00 -6.00 -1.43 2.00 -3.00 -5.50 -1.57 2.50 -2.75 -5.00 -1.71 3.00 -2.50 -4.50 -1.86 3.50 -2.25 -4.00 -2.00 4.00 -2.00 -3.50 -2.25 4.50 -1.86 -3.00 -2.50 5.00 -1.71 -2.50 -2.75 5.50 -1.57 -2.00 -3.00 6.00 -1.43 -1.50 -3.00 6.50 -1.29 -1.00 -3.00 7.00 -1.14 -0.50 -3.00 7.50 -1.00 0.00 -3.00

The material of the multifocal contact lens of the seventh embodiment is hydrogel. Please refer to Table 21A for the composition of the hydrogel of the seventh embodiment. Table 21A Element Content (wt%) Hydroxyethyl Methacrylate 82 Tetraphenyl dimethacrylate 1 Ethylene glycol dimethacrylate 0.4 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 glycerin 13.5 Trihydroxymethylpropane trimethacrylate 0.2 Methacrylic acid 2.3

It can be seen from Table 21A that by adding tetraphenyl dimethacrylate, the multi-focal contact lens of the seventh embodiment can absorb blue light.

Please refer to FIG. 14, which is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the seventh embodiment and the multifocal contact lenses of the third comparative example. The difference between the third comparative example and the seventh embodiment is that the third comparative example does not add a blue light absorbing component. Specifically, the third comparative example replaces tetraphenyl dimethacrylate with hydroxyethyl methacrylate. The blocking rate of the multifocal contact lenses of the third comparative example and the seventh embodiment for blue light (wavelength range 380nm~495nm) can be inferred from FIG. 14. The calculation method is as follows: (1-average transmittance of wavelength 380~495nm)*100%, and the results are listed in Table 21B. Table 21B The third comparison example Seventh embodiment Blue light blocking rate (%) (380 nm ~ 495 nm) 8.21 35.53

It can be seen from Table 21B that, compared with the third comparative example, the seventh embodiment has a much greater blue light blocking rate than the third comparative example. In other words, the multifocal contact lenses of the seventh embodiment can effectively absorb blue light, thereby reducing the probability of the retina being damaged by blue light.

<Eighth Embodiment>

The multifocal contact lens of the eighth embodiment comprises a central area and a first annular area, wherein the first annular area concentrically surrounds the central area, and at least one of the central area and the first annular area is an aspherical surface. For the structure of the multifocal contact lens of the eighth embodiment, please refer to FIG. 2 .

In the multifocal contact lens of the eighth embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the refractive power of the central area is PowC, and the maximum refractive power of the first annular area is PowP1. For the values of DiC, DiP1, DiC/DiP1, PowC, PowP1, and |PowC – PowP1| of the eighth embodiment, please refer to Table 22. Table 22. Eighth Embodiment DiC (mm) 5.00 PowC (D) -3.50 DiP1 (mm) 10.00 PowP1 (D) -1.75 DiC/DiP1 0.50 |PowC – PowP1| (D) 1.75

Please refer to Table 23 and Figure 15 at the same time. Table 23 lists the radius of the multifocal contact lens of the eighth embodiment and its corresponding diopter. Figure 15 is a relationship diagram between the radius and diopter of the multifocal contact lens of the eighth embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 23 and Figure 15 that the diopter of the central area is fixed, and the diopter of the first annular area is different from the diopter of the central area. Specifically, the diopter of the first annular area is greater than that of the central area, and the diopter of the first annular area increases as it is farther away from the central area. Table 23. Eighth Embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -5.00 -1.75 0.50 -3.50 -4.50 -2.10 1.00 -3.50 -4.00 -2.45 1.50 -3.50 -3.50 -2.80 2.00 -3.50 -3.00 -3.15 2.50 -3.50 -2.50 -3.50 3.00 -3.15 -2.00 -3.50 3.50 -2.80 -1.50 -3.50 4.00 -2.45 -1.00 -3.50 4.50 -2.10 -0.50 -3.50 5.00 -1.75 0.00 -3.50

The material of the multifocal contact lens of the eighth embodiment is hydrogel. Please refer to Table 24 for the composition of the hydrogel of the eighth embodiment. Table 24 Element Content (wt%) Hydroxyethyl Methacrylate 45 Tetraphenyl dimethacrylate 1 Ethylene glycol dimethacrylate 0.5 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 glycerin 10.6 Trihydroxymethylpropane trimethacrylate 0.3 2-Methyl-2-acrylate-2,3-dihydroxypropyl ester 42

It can be seen from Table 24 that by adding tetraphenyl dimethacrylate, the multi-focal contact lens of the eighth embodiment can absorb blue light.

<Ninth Embodiment>

The multifocal contact lens of the ninth embodiment comprises a central area, a first annular area and a second annular area. The central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. At least one of the central area, the second annular area and the first annular area is an aspherical surface. The structure of the multifocal contact lens of the ninth embodiment can be referred to FIG. 3 .

In the multifocal contact lens of the ninth embodiment, the diameter of the central zone is DiC, the outer diameter of the first annular zone is DiP1, the outer diameter of the second annular zone is DiP2, the diopter of the central zone is PowC, the maximum diopter of the first annular zone is PowP1, and the maximum diopter of the second annular zone is PowP2. For the values of DiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, and |PowC – PowP1| of the ninth embodiment, please refer to Table 25. Table 25. Ninth Embodiment DiC (mm) 6.00 PowC (D) -4.00 DiP1 (mm) 14.00 PowP1 (D) -3.25 DiP2 (mm) 10.00 PowP2 (D) -3.75 DiC/DiP1 0.43 |PowC – PowP1| (D) 0.75 DiC/DiP2 0.60

Please refer to Table 26 and Figure 16. Table 26 lists the radius of the multifocal contact lens of the ninth embodiment and its corresponding diopter. Figure 16 is a relationship diagram between the radius and diopter of the multifocal contact lens of the ninth embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 26 and Figure 16 that the diopter of the central area is fixed, and the diopter of the second area is fixed. The refractive power of the annular zone is different from that of the central zone, and the refractive power of the first annular zone is different from that of the central zone. Specifically, the refractive power of the second annular zone is greater than that of the central zone, and the refractive power of the second annular zone increases as it moves away from the central zone, and the refractive power of the first annular zone is greater than that of the central zone, and the refractive power of the first annular zone increases as it moves away from the central zone. Table 26. Ninth Embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -7.00 -3.25 0.50 -4.00 -6.50 -3.38 1.00 -4.00 -6.00 -3.50 1.50 -4.00 -5.50 -3.63 2.00 -4.00 -5.00 -3.75 2.50 -4.00 -4.50 -3.81 3.00 -4.00 -4.00 -3.88 3.50 -3.94 -3.50 -3.94 4.00 -3.88 -3.00 -4.00 4.50 -3.81 -2.50 -4.00 5.00 -3.75 -2.00 -4.00 5.50 -3.63 -1.50 -4.00 6.00 -3.50 -1.00 -4.00 6.50 -3.38 -0.50 -4.00 7.00 -3.25 0.00 -4.00

The material of the multifocal contact lens of the ninth embodiment is hydrogel. Please refer to Table 27 for the composition of the hydrogel prepared in the ninth embodiment. Table 27 Element Content (wt%) Hydroxyethyl Methacrylate 90.3 Tetraphenyl dimethacrylate 1.2 Ethylene glycol dimethacrylate 0.6 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 glycerin 6.5 N-vinyl-2-pyrrolidone 0.8

It can be seen from Table 27 that by adding tetraphenyl dimethacrylate, the multi-focal contact lens of the ninth embodiment can absorb blue light.

<Tenth Embodiment>

The multifocal contact lens of the tenth embodiment comprises a central area and a first annular area, wherein the first annular area concentrically surrounds the central area, and at least one of the central area and the first annular area is an aspherical surface. For the structure of the multifocal contact lens of the tenth embodiment, please refer to FIG. 2 .

In the multifocal contact lens of the tenth embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the refractive power of the central area is PowC, and the maximum refractive power of the first annular area is PowP1. For the values of DiC, DiP1, DiC/DiP1, PowC, PowP1, and |PowC – PowP1| of the tenth embodiment, please refer to Table 28. Table 28, Tenth Embodiment DiC (mm) 7.00 PowC (D) -4.50 DiP1 (mm) 12.00 PowP1 (D) -3.00 DiC/DiP1 0.58 |PowC – PowP1| (D) 1.50

Please refer to Table 29 and Figure 17 at the same time. Table 29 lists the radius of the multifocal contact lens of the tenth embodiment and its corresponding diopter. Figure 17 is a relationship diagram between the radius and diopter of the multifocal contact lens of the tenth embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 29 and Figure 17 that the diopter of the central area is fixed, and the diopter of the first annular area is different from the diopter of the central area. Specifically, the diopter of the first annular area is greater than that of the central area, and the diopter of the first annular area increases as it is farther away from the central area. Table 29, Tenth Embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -6.00 -3.00 0.50 -4.50 -5.50 -3.30 1.00 -4.50 -5.00 -3.60 1.50 -4.50 -4.50 -3.90 2.00 -4.50 -4.00 -4.20 2.50 -4.50 -3.50 -4.50 3.00 -4.50 -3.00 -4.50 3.50 -4.50 -2.50 -4.50 4.00 -4.20 -2.00 -4.50 4.50 -3.90 -1.50 -4.50 5.00 -3.60 -1.00 -4.50 5.50 -3.30 -0.50 -4.50 6.00 -3.00 0.00 -4.50

The material of the multifocal contact lens of the tenth embodiment is silicone hydrogel. Please refer to Table 30 for the composition of the silicone hydrogel prepared in the tenth embodiment. Table 30 Element Content (wt%) Hydroxyethyl Methacrylate 4.3 Methacryloyloxypropyl tris(trimethylsiloxy)silane 28 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 N-vinyl-2-pyrrolidone 20.2 N,N-Dimethylacrylamide 12.3 Ethylene glycol dimethacrylate 0.6 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate 1 (3-Methacryloyloxy-2-hydroxypropoxy)propylbis(trimethylsilyl)methyl 21.5 Isopropyl alcohol 10 Methacrylic acid 1.5

As shown in Table 30, by adding 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate, the multifocal contact lens of the tenth embodiment can absorb UV light.

＜Eleventh Embodiment＞

The multifocal contact lens of the eleventh embodiment comprises a central area, a first annular area and a second annular area. The central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. At least one of the central area, the second annular area and the first annular area is an aspherical surface. The structure of the multifocal contact lens of the eleventh embodiment can be referred to FIG. 3 .

In the multifocal contact lens of the eleventh embodiment, the diameter of the central area is DiC, the outer diameter of the first annular area is DiP1, the outer diameter of the second annular area is DiP2, the refractive power of the central area is PowC, the maximum refractive power of the first annular area is PowP1, and the maximum refractive power of the second annular area is PowP2. For the values of DiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, and |PowC – PowP1| of the eleventh embodiment, please refer to Table 31. Table 31. Eleventh Embodiment DiC (mm) 8.00 PowC (D) -5.00 DiP1 (mm) 13.00 PowP1 (D) -2.75 DiP2 (mm) 10.00 PowP2 (D) -4.00 DiC/DiP1 0.62 |PowC – PowP1| (D) 2.25 DiC/DiP2 0.80

Please refer to Table 32 and FIG. 18. Table 32 lists the radius of the multifocal contact lens of the eleventh embodiment and its corresponding diopter. FIG. 18 is a relationship diagram between the radius and diopter of the multifocal contact lens of the eleventh embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 32 and FIG. 18 that the diopter of the central area is fixed, The refractive power of the second annular zone is different from that of the central zone, and the refractive power of the first annular zone is different from that of the central zone. Specifically, the refractive power of the second annular zone is greater than that of the central zone, and the refractive power of the second annular zone increases as it moves away from the central zone, and the refractive power of the first annular zone is greater than that of the central zone, and the refractive power of the first annular zone increases as it moves away from the central zone. Table 32. Eleventh Embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -6.50 -2.75 0.50 -5.00 -6.00 -3.17 1.00 -5.00 -5.50 -3.58 1.50 -5.00 -5.00 -4.00 2.00 -5.00 -4.50 -4.50 2.50 -5.00 -4.00 -5.00 3.00 -5.00 -3.50 -5.00 3.50 -5.00 -3.00 -5.00 4.00 -5.00 -2.50 -5.00 4.50 -4.50 -2.00 -5.00 5.00 -4.00 -1.50 -5.00 5.50 -3.58 -1.00 -5.00 6.00 -3.17 -0.50 -5.00 6.50 -2.75 0.00 -5.00

The material of the multifocal contact lens of the eleventh embodiment is silicone hydrogel. Please refer to Table 33A for the composition of the silicone hydrogel prepared in the eleventh embodiment. Table 33A Element Content (wt%) Hydroxyethyl Methacrylate 4 Methacryloyloxypropyl tris(trimethylsiloxy)silane 28 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 N-vinyl-2-pyrrolidone 20.5 N,N-Dimethylacrylamide 12.3 Ethylene glycol dimethacrylate 0.5 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate 1.1 3-Acetyloxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane twenty two n-Hexanol 11

As shown in Table 33A, by adding 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate, the multifocal contact lens of the eleventh embodiment can absorb UV light.

Please refer to FIG. 19, which is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the eleventh embodiment and the multifocal contact lenses of the fourth comparative example. The difference between the fourth comparative example and the eleventh embodiment is that the fourth comparative example does not add a UV absorbing component. Specifically, the fourth comparative example replaces 2-(4-benzoyl-3-hydroxyphenoxy)ethyl 2-acrylate with hydroxyethyl methacrylate. From FIG. 19, it can be inferred that the multifocal contact lenses of the fourth comparative example and the eleventh embodiment have a UV absorption component of 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate. The blocking rate of UV-A (UV light with a wavelength range of 316nm~380nm) is calculated as follows: (1-average transmittance of wavelength 316~380nm)*100%, and the blocking rate of UV-B (UV light with a wavelength range of 280nm~315nm) of the multifocal contact lenses of the fourth comparative example and the eleventh embodiment is calculated as follows: (1-average transmittance of 280nm~315nm)×100%, and the results are listed in Table 33B. Table 33B Fourth Comparison Example Eleventh Embodiment UV-A blocking rate (%) (316 nm ~380 nm) 15.02 90.01 UV-B blocking rate (%) (280 nm ~315 nm) 40.91 99.24

As shown in Table 33B, compared with the fourth comparative example, the blocking rate of UV-A and UV-B of the eleventh embodiment are much greater than those of the fourth comparative example. In other words, the multifocal contact lenses of the eleventh embodiment can effectively absorb UV light, thereby reducing the probability of the retina being damaged by UV light.

＜Twelfth Embodiment＞

The multifocal contact lens of the twelfth embodiment comprises a central area, a first annular area, a second annular area and a third annular area. The central area, the third annular area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center. At least one of the central area, the third annular area, the second annular area and the first annular area is an aspherical surface. The structure of the multifocal contact lens of the twelfth embodiment can be referred to FIG. 4.

In the multifocal contact lens of the twelfth embodiment, the diameter of the central zone is DiC, the outer diameter of the first annular zone is DiP1, the outer diameter of the second annular zone is DiP2, the outer diameter of the third annular zone is DiP3, the refractive power of the central zone is PowC, the maximum refractive power of the first annular zone is PowP1, the maximum refractive power of the second annular zone is PowP2, and the maximum refractive power of the third annular zone is PowP3. For the values of DiC, DiP1, DiP2, DiP3, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, PowP3, and |PowC – PowP1| of the twelfth embodiment, please refer to Table 34. Table 34. Twelfth Embodiment DiC (mm) 4.00 PowC (D) -5.50 DiP1 (mm) 16.00 PowP1 (D) -3.00 DiP2 (mm) 12.00 PowP2 (D) -3.00 DiP3 (mm) 8.00 PowP3 (D) -3.75 DiC/DiP1 0.25 |PowC – PowP1| (D) 2.50 DiC/DiP2 0.33

Please refer to Table 35 and Figure 20. Table 35 lists the radius of the multifocal contact lens of the twelfth embodiment and its corresponding diopter. Figure 20 is a relationship diagram between the radius and diopter of the multifocal contact lens of the twelfth embodiment (negative values only indicate the radius distance in the opposite direction). It can be seen from Table 35 and Figure 20 that the diopter of the central area is fixed, the diopter of the third annular area is different from the diopter of the central area, and the diopter of the second annular area is different from the diopter of the central area. The diopter of the first annular zone is different from the diopter of the central zone, and the diopter of the first annular zone is different from the diopter of the central zone. Specifically, the diopter of the third annular zone is greater than that of the central zone, and the diopter of the third annular zone increases as it moves away from the central zone, the diopter of the second annular zone is greater than that of the central zone, and the diopter of the second annular zone increases as it moves away from the central zone, and the diopter of the first annular zone is greater than that of the central zone, and the diopter of the first annular zone is fixed. Table 35. Twelfth Embodiment Radius(mm) Diopter (D) Radius(mm) Diopter (D) -8.00 -3.00 0.50 -5.50 -7.50 -3.00 1.00 -5.50 -7.00 -3.00 1.50 -5.50 -6.50 -3.00 2.00 -5.50 -6.00 -3.00 2.50 -5.06 -5.50 -3.19 3.00 -4.63 -5.00 -3.38 3.50 -4.19 -4.50 -3.56 4.00 -3.75 -4.00 -3.75 4.50 -3.56 -3.50 -4.19 5.00 -3.38 -3.00 -4.63 5.50 -3.19 -2.50 -5.06 6.00 -3.00 -2.00 -5.50 6.50 -3.00 -1.50 -5.50 7.00 -3.00 -1.00 -5.50 7.50 -3.00 -0.50 -5.50 8.00 -3.00 0.00 -5.50

The material of the multifocal contact lens of the twelfth embodiment is silicone hydrogel. Please refer to Table 36A for the composition of the hydrogel of the twelfth embodiment. Table 36A Element Content (wt%) Hydroxyethyl Methacrylate 4.2 Methacryloyloxypropyl tris(trimethylsiloxy)silane 26 2-Hydroxy-2-methyl-1-phenyl-1-propanone 0.6 N-vinyl-2-pyrrolidone 20 N,N-Dimethylacrylamide 11 Dimethylsiloxane modified urethane oligomer twenty four Tetraphenyl dimethacrylate 1 Methyl Methacrylate 4.2 Ethanol 9

It can be seen from Table 36A that by adding tetraphenyl dimethacrylate, the multi-focal contact lens of the twelfth embodiment can absorb blue light.

Please refer to FIG. 21, which is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the twelfth embodiment and the multifocal contact lenses of the fifth comparative example. The difference between the fifth comparative example and the twelfth embodiment is that the fifth comparative example does not add a blue light absorbing component. Specifically, the fifth comparative example replaces tetraphenyl dimethacrylate with hydroxyethyl methacrylate. The blocking rate of the multifocal contact lenses of the fifth comparative example and the twelfth embodiment for blue light (wavelength range 380nm~495nm) can be inferred from FIG. 21. The calculation method is as follows: (1-average transmittance of wavelength 380~495nm)*100%, and the results are listed in Table 36B. Table 36B Comparison Example 5 Twelfth Embodiment Blue light blocking rate (%) (380 nm ~ 495 nm) 10.31 16.32

It can be seen from Table 36B that, compared with the fifth comparative example, the blue light blocking rate of the twelfth embodiment is much greater than that of the fifth comparative example. In other words, the multifocal contact lenses of the twelfth embodiment can effectively absorb blue light, thereby reducing the probability of the retina being damaged by blue light.

In the present invention, the aspheric surface on the multifocal contact lens refers to the curved surface shape of the front surface or the back surface under the cross-center section, wherein the front surface refers to the surface far from the cornea of the eyeball, and the back surface refers to the surface close to the cornea of the eyeball.

The diopter in the present invention is represented by a D value, where the diopter of a lens for correcting myopia is a negative value and the diopter of a lens for correcting hyperopia is a positive value.

The ciliary muscle paralytic agents of the present invention include but are not limited to atropine ((3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl tropate), tropicamide (N-Ethyl-3-hydroxy-2-phenyl-N-(4-pyridinylmethyl)propanamide), cyclopentolate (2-(Dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate), homatropine ((3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate), scopolamine ((1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.0 ^2,4 ]non-7-yl(2S)-3-hydroxy-2-phenylpropanoate) and eucatropine (Eucatropine; 1,2,2,6-Tetramethyl-4-piperidinyl hydroxy(phenyl)acetate) and their salts. Ciliary muscle anesthetics are also called mydriatics and belong to the class of parasympathetic nerve blockers, that is, they are non-selective M-type muscarinic receptor blockers that can paralyze and relax the ciliary muscles that control the pupil by blocking muscarinic receptors, thereby dilating the pupil.

Although the present invention has been disclosed in the above embodiments, it is not intended to limit the present invention. Anyone skilled in the art can make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention shall be determined by the scope of the attached patent application.

100: Contact lens products 110,210,310: Multifocal contact lenses 111,211,311: Central zone 112,212,312: First annular zone 120: Buffer solution 213,313: Second annular zone 314: Third annular zone DiC: Diameter of central zone DiP1: Outer diameter of first annular zone DiP2: Outer diameter of second annular zone DiP3: Outer diameter of third annular zone PowC: Refractive power of central zone PowP1: Maximum refractive power of first annular zone PowP2: Maximum refractive power of second annular zone PowP3: Maximum refractive power of third annular zone

In order to make the above and other purposes, features, advantages and embodiments of the present invention more clearly understandable, the attached drawings are described as follows: FIG. 1 is a schematic diagram of a contact lens product according to an embodiment of the present invention; FIG. 2 is a plan view of the multifocal contact lens in FIG. 1; FIG. 3 is a plan view of a multifocal contact lens according to another embodiment of the present invention; FIG. 4 is a plan view of a multifocal contact lens according to another embodiment of the present invention; FIG. 5 is a relationship diagram between the radius and the diopter of the multifocal contact lens of the first embodiment; FIG. 6 is a relationship diagram between the radius and the diopter of the multifocal contact lens of the second embodiment; Figure 7 is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the second embodiment and the multifocal contact lenses of the first comparative example; Figure 8 is a graph showing the relationship between radius and diopter of the multifocal contact lenses of the third embodiment; Figure 9 is a graph showing the relationship between radius and diopter of the multifocal contact lenses of the fourth embodiment; Figure 10 is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the fourth embodiment and the multifocal contact lenses of the second comparative example; Figure 11 is a graph showing the relationship between radius and diopter of the multifocal contact lenses of the fifth embodiment; Figure 12 is a graph showing the relationship between radius and diopter of the multifocal contact lenses of the sixth embodiment; Figure 13 is a relationship diagram between the radius and the diopter of the multifocal contact lens of the seventh embodiment; Figure 14 is a relationship diagram between the wavelength and the light transmittance of the multifocal contact lens of the seventh embodiment and the multifocal contact lens of the third comparison example; Figure 15 is a relationship diagram between the radius and the diopter of the multifocal contact lens of the eighth embodiment; Figure 16 is a relationship diagram between the radius and the diopter of the multifocal contact lens of the ninth embodiment; Figure 17 is a relationship diagram between the radius and the diopter of the multifocal contact lens of the tenth embodiment; Figure 18 is a relationship diagram between the radius and the diopter of the multifocal contact lens of the eleventh embodiment; FIG. 19 is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the eleventh embodiment and the multifocal contact lenses of the fourth comparative example; FIG. 20 is a graph showing the relationship between radius and diopter of the multifocal contact lenses of the twelfth embodiment; and FIG. 21 is a graph showing the relationship between wavelength and light transmittance of the multifocal contact lenses of the twelfth embodiment and the multifocal contact lenses of the fifth comparative example.

100: Contact lens products

110: Multifocal contact lenses

120: Buffer solution

Claims (11)

A contact lens product, comprising: A multifocal contact lens, comprising: A central area; and At least two annular areas, namely a first annular area and a second annular area, wherein the central area, the second annular area and the first annular area are sequentially connected from the center to the periphery and have the same center, wherein the refractive power of the second annular area is different from the refractive power of the central area, and the refractive power of the first annular area is different from the refractive power of the central area; and A buffer solution, wherein the multifocal contact lens is immersed in the buffer solution; The refractive power of the central area of the multifocal contact lens is PowC, the maximum refractive power of the first annular area of the multifocal contact lens is PowP1, the diameter of the central area of the multifocal contact lens is DiC, the outer diameter of the first annular area of the multifocal contact lens is DiP1, and the outer diameter of the second annular area of the multifocal contact lens is DiP2, which meets the following conditions: 2 D ＜ |PowC–PowP1|; 0.15 ≤ DiC/DiP1 ≤ 1; and 0.2 ≤ DiC/DiP2 ≤ 1. The contact lens product as described in claim 1, wherein the refractive power of the central zone of the multifocal contact lens is PowC, and the maximum refractive power of the first annular zone of the multifocal contact lens is PowP1, which satisfies the following conditions: 2.25 D ≤ |PowC–PowP1|. The contact lens product as described in claim 1, wherein the diameter of the central area of the multifocal contact lens is DiC, and the outer diameter of the first annular area of the multifocal contact lens is DiP1, which meets the following conditions: 0.2 ≤ DiC/DiP1 ≤ 0.7. The contact lens product as described in claim 1, wherein the diameter of the central area of the multifocal contact lens is DiC, and the outer diameter of the second annular area of the multifocal contact lens is DiP2, which meets the following conditions: 0.3 ≤ DiC/DiP2 ≤ 0.85. The contact lens product as claimed in claim 1, wherein the buffer solution comprises a ciliary muscle anesthetic. The contact lens product as described in claim 5, wherein the weight percentage concentration of the ciliary muscle paralytic in the buffer solution is ConA, which satisfies the following conditions: 0.01% ≤ ConA ＜ 0.5%. The contact lens product as described in claim 6, wherein the weight percentage concentration of the ciliary muscle paralytic in the buffer solution is ConA, which satisfies the following conditions: 0.1% ≤ ConA ≤ 0.25%. A contact lens product as described in claim 1, wherein the material of the multifocal contact lens is silicone hydrogel. A contact lens product as described in claim 8, wherein the composition of the silicone hydrogel includes a blue light absorbing component. The contact lens product as described in claim 9, wherein the blue light absorbing component is 4-(phenyldiazenyl) phenyl methacrylate. The contact lens product as described in claim 10, wherein the weight percentage of the blue light absorbing component in the silicone hydrogel composition is 0.1% to 5%.

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