TWI561245B - Conjugate comprising erythropoietin and a branched polymeric structure - Google Patents
Conjugate comprising erythropoietin and a branched polymeric structureInfo
- Publication number
- TWI561245B TWI561245B TW104100285A TW104100285A TWI561245B TW I561245 B TWI561245 B TW I561245B TW 104100285 A TW104100285 A TW 104100285A TW 104100285 A TW104100285 A TW 104100285A TW I561245 B TWI561245 B TW I561245B
- Authority
- TW
- Taiwan
- Prior art keywords
- erythropoietin
- conjugate
- polymeric structure
- branched polymeric
- branched
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Polyethers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CUP2014000003A CU20140003A7 (en) | 2014-01-08 | 2014-01-08 | CONJUGATE UNDERSTANDING ERYTHROPOYETIN AND A RAMIFIED POLYMER STRUCTURE |
Publications (2)
Publication Number | Publication Date |
---|---|
TW201538168A TW201538168A (en) | 2015-10-16 |
TWI561245B true TWI561245B (en) | 2016-12-11 |
Family
ID=52573994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW104100285A TWI561245B (en) | 2014-01-08 | 2015-01-06 | Conjugate comprising erythropoietin and a branched polymeric structure |
Country Status (17)
Country | Link |
---|---|
US (1) | US20160317674A1 (en) |
EP (1) | EP3093024A1 (en) |
JP (1) | JP6367952B2 (en) |
KR (1) | KR20160105811A (en) |
CN (1) | CN106163541A (en) |
AR (1) | AR099045A1 (en) |
AU (1) | AU2015205774B2 (en) |
CA (1) | CA2935306A1 (en) |
CU (1) | CU20140003A7 (en) |
EA (1) | EA201691386A1 (en) |
IL (1) | IL246526A0 (en) |
MX (1) | MX2016008928A (en) |
NZ (1) | NZ722092A (en) |
SG (1) | SG11201604984TA (en) |
TW (1) | TWI561245B (en) |
WO (1) | WO2015104008A1 (en) |
ZA (1) | ZA201604636B (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1479711A1 (en) * | 2002-01-15 | 2004-11-24 | Pan Asia Bio (Shanghai) Co., Ltd | Multidrop tree branching functional polyethylene glycol, the preparation method and the use of it |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6514533B1 (en) | 1992-06-11 | 2003-02-04 | Alkermas Controlled Therapeutics, Inc. | Device for the sustained release of aggregation-stabilized, biologically active agent |
US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
DE60109625T3 (en) | 2000-05-15 | 2017-08-03 | F. Hoffmann-La Roche Ag | LIQUID MEDICINE PREPARATION CONTAINING AN ERYTHROPOIETIN DERIVATIVE |
EA013535B1 (en) * | 2002-12-26 | 2010-06-30 | Маунтин Вью Фамэсьютикэлс, Инк. | Polymer conjugate of bioactive component (variants), method for producing and use thereof, pharmaceutical products on the base thereof |
WO2006061853A2 (en) * | 2004-12-10 | 2006-06-15 | Serum Institute Of India Limited | Novel erythropoietic compounds and a process for producing erythropoietic compounds |
CU23556A1 (en) * | 2005-11-30 | 2010-07-20 | Ct Ingenieria Genetica Biotech | POLYMER STRUCTURE SIMILAR TO DENDRÍMERO FOR THE OBTAINING OF CONJUGATES OF PHARMACEUTICAL INTEREST |
PT2054074E (en) * | 2006-08-04 | 2014-11-07 | Prolong Pharmaceuticals Llc | Modified erythropoietin |
WO2008056654A1 (en) * | 2006-11-08 | 2008-05-15 | Nippon Kayaku Kabushiki Kaisha | Polymeric derivative of nucleic acid metabolic antagonist |
CN101376676B (en) * | 2008-10-09 | 2012-04-25 | 天津派格生物技术有限公司 | PEGylated erythropoietin protein long-acting preparation |
-
2014
- 2014-01-08 CU CUP2014000003A patent/CU20140003A7/en unknown
-
2015
- 2015-01-06 TW TW104100285A patent/TWI561245B/en not_active IP Right Cessation
- 2015-01-08 CA CA2935306A patent/CA2935306A1/en not_active Abandoned
- 2015-01-08 WO PCT/CU2015/000001 patent/WO2015104008A1/en active Application Filing
- 2015-01-08 AU AU2015205774A patent/AU2015205774B2/en not_active Ceased
- 2015-01-08 CN CN201580004018.1A patent/CN106163541A/en active Pending
- 2015-01-08 EP EP15705897.5A patent/EP3093024A1/en not_active Withdrawn
- 2015-01-08 AR ARP150100036A patent/AR099045A1/en unknown
- 2015-01-08 NZ NZ722092A patent/NZ722092A/en not_active IP Right Cessation
- 2015-01-08 MX MX2016008928A patent/MX2016008928A/en unknown
- 2015-01-08 KR KR1020167018696A patent/KR20160105811A/en not_active Application Discontinuation
- 2015-01-08 EA EA201691386A patent/EA201691386A1/en unknown
- 2015-01-08 JP JP2016545283A patent/JP6367952B2/en not_active Expired - Fee Related
- 2015-01-08 SG SG11201604984TA patent/SG11201604984TA/en unknown
- 2015-01-08 US US15/108,862 patent/US20160317674A1/en not_active Abandoned
-
2016
- 2016-06-29 IL IL246526A patent/IL246526A0/en unknown
- 2016-07-07 ZA ZA2016/04636A patent/ZA201604636B/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1479711A1 (en) * | 2002-01-15 | 2004-11-24 | Pan Asia Bio (Shanghai) Co., Ltd | Multidrop tree branching functional polyethylene glycol, the preparation method and the use of it |
Also Published As
Publication number | Publication date |
---|---|
US20160317674A1 (en) | 2016-11-03 |
WO2015104008A1 (en) | 2015-07-16 |
AU2015205774B2 (en) | 2017-11-30 |
TW201538168A (en) | 2015-10-16 |
JP2017506619A (en) | 2017-03-09 |
KR20160105811A (en) | 2016-09-07 |
ZA201604636B (en) | 2018-05-30 |
EP3093024A1 (en) | 2016-11-16 |
IL246526A0 (en) | 2016-08-31 |
SG11201604984TA (en) | 2016-07-28 |
EA201691386A1 (en) | 2016-11-30 |
CN106163541A (en) | 2016-11-23 |
MX2016008928A (en) | 2016-10-04 |
WO2015104008A8 (en) | 2016-08-25 |
NZ722092A (en) | 2017-11-24 |
AU2015205774A1 (en) | 2016-07-28 |
AR099045A1 (en) | 2016-06-22 |
CU20140003A7 (en) | 2015-08-27 |
CA2935306A1 (en) | 2015-07-16 |
JP6367952B2 (en) | 2018-08-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11201704703UA (en) | Multi-faceted compute instance identity | |
SG11201609490QA (en) | Polymer-flavonoid conjugate and uses thereof | |
EP3102150C0 (en) | Polymer composite-covered stents | |
ZA201603892B (en) | Dye polymer | |
IL258759A (en) | Anti-cd3-folate conjugates and their uses | |
EP3204569A4 (en) | Strength retention fabric | |
IL252833A0 (en) | Biodegradable polymer | |
PT3164549T (en) | Structures comprising polymeric fibers | |
SG11201607649XA (en) | A dam | |
GB201418068D0 (en) | Polymer | |
SG11201605591SA (en) | Polyester polymers comprising lignin | |
GB201706658D0 (en) | Branched Polymers | |
SI3383937T1 (en) | Improved polymer preparation | |
HUE054880T2 (en) | Apertured web | |
GB201402404D0 (en) | Polymer | |
GB2539397B (en) | Micro Farm | |
GB2523112B (en) | Ditches | |
ZA201704564B (en) | Microdialysis device | |
ZA201604636B (en) | Conjugate comprising erythropoietin and a branched polymeric structure | |
GB201613166D0 (en) | Polymer | |
GB201717349D0 (en) | Polymer | |
GB201617923D0 (en) | Polymer | |
GB201608952D0 (en) | Polymer | |
GB201522434D0 (en) | Polymer | |
GB2541909B (en) | Bollard |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Annulment or lapse of patent due to non-payment of fees |