TW248558B - - Google Patents

Info

Publication number: TW248558B
Authority: TW; Taiwan

Application number

TW082107947A

Other languages

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-30

Filing date

1993-09-27

Publication date

1995-06-01

1993-09-27 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1995-06-01 Application granted granted Critical

1995-06-01 Publication of TW248558B publication Critical patent/TW248558B/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Otolaryngology (AREA)
Addiction (AREA)
Reproductive Health (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)

TW082107947A 1992-09-30 1993-09-27 TW248558B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/954,105 US5364856A (en)	1991-03-28	1992-09-30	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles

Publications (1)

Publication Number	Publication Date
TW248558B true TW248558B (en)	1995-06-01

Family

ID=25494930

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW082107947A TW248558B (en)	1992-09-30	1993-09-27

Country Status (15)

Country	Link
US (10)	US5364856A (en)
EP (2)	EP1000621A3 (en)
JP (1)	JPH06211655A (en)
KR (1)	KR940006584A (en)
CN (1)	CN1056144C (en)
AU (1)	AU676849B2 (en)
CA (1)	CA2107010A1 (en)
CZ (1)	CZ9302010A3 (en)
HU (1)	HUT66076A (en)
IL (1)	IL107125A (en)
MX (1)	MX9305998A (en)
NO (1)	NO933477L (en)
RU (1)	RU2138262C1 (en)
TW (1)	TW248558B (en)
ZA (1)	ZA937153B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5347013A (en) *	1991-03-28	1994-09-13	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5627199A (en) *	1991-03-28	1997-05-06	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz [CD] indoles
TW248556B (en) *	1993-01-18	1995-06-01	Takeda Pharm Industry Co
US5385928A (en) *	1994-05-18	1995-01-31	Eli Lilly And Company	Tetrahydrobenz [CD] indazoles, compositions and use
US5990114A (en) *	1996-02-28	1999-11-23	Recordati, S.A., Chemical And Pharmaceutical Company	Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
WO1999064044A1 (en) *	1998-06-08	1999-12-16	Advanced Medicine, Inc.	Novel therapeutic agents that modulate 5-ht receptors
AU4641400A (en) *	1999-06-02	2000-12-18	Ishihara Sangyo Kaisha Ltd.	Fused tricyclic compounds, process for their preparation, and herbicidal compositions containing them
US6770596B1 (en)	2000-04-21	2004-08-03	Ishihara Sangyo Kaisha Ltd.	Fused tricyclic compounds, process for their preparation, and herbicidal compositions containing them
JP6348481B2 (en)	2012-03-30	2018-06-27	ジーイー・ヘルスケア・バイオサイエンス・コーポレイション	Method for generating an image of a tissue sample
CN111265268A (en) *	2018-12-05	2020-06-12	苏州英途康医疗科技有限公司	Medical instrument

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3194811A (en) *	1963-09-05	1965-07-13	Merck & Co Inc	Aroyl-benzindolyl acids
BE755270A (en) *	1969-08-27	1971-02-25	Sandoz Sa	NEW DERIVATIVES OF BENZO (CD) INDOLE, THEIR PREPARATION AND MEDICINAL PRODUCTS CONTAINING THESE DERIVATIVES
BE757879A (en) *	1969-10-24	1971-04-22	Sandoz Sa	BENZO (CD) INDOLE DERIVATIVES, THEIR PREPARATION AND MEDICINAL PRODUCTS CONTAINING SUCH DERIVATIVES
CH517732A (en) *	1969-10-24	1972-01-15	Sandoz Ag	Guanidine derivs - with stimulant psychotherapeutic, sali-diuretic and antipyretic activity
FI206974A (en) *	1973-07-16	1975-01-17	Sandoz Ag
US4110339A (en) *	1977-11-25	1978-08-29	Eli Lilly And Company	4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
US4282240A (en) *	1979-11-23	1981-08-04	Merck & Co., Inc.	Amino substituted tetrahydrobenzindoles
FR2510111A1 (en) *	1981-07-24	1983-01-28	Roussel Uclaf	NOVEL DERIVATIVES OF PIPERIDIN-3-YL INDOLE, THEIR SALTS, PROCESS FOR PREPARING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
FR2522658A1 (en) *	1982-03-05	1983-09-09	Roussel Uclaf	APPLICATION AS MEDICAMENTS OF 4-AMINO BENZ TRANSDUCERS (C, D) INDOL-5-OL AND THEIR SALTS, COMPOSITIONS COMPRISING THEM, NOVEL DERIVATIVES AND PROCESS FOR THEIR PREPARATION
JPS5969151A (en) *	1982-10-13	1984-04-19	Unitika Ltd	Spherical ion exchange resin and its production and adsorptive treatment
DE3346573A1 (en) *	1983-12-23	1985-07-04	Troponwerke GmbH & Co KG, 5000 Köln	1,3,4,5-TETRAHYDROBENZ (C, D) INDOLE, A METHOD FOR THE PRODUCTION AND THEIR USE
IL74222A (en) *	1984-02-06	1988-07-31	Lilly Co Eli	6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
US4983622A (en) *	1984-02-06	1991-01-08	Eli Lilly And Company	6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
US4576959A (en) *	1984-02-06	1986-03-18	Eli Lilly And Company	6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) *	1984-05-24	1990-03-06	Carl Kaiser	6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
DE3525564A1 (en) *	1985-07-15	1987-02-05	Schering Ag	TRICYCLIC COMPOUNDS WITH INDOLSTRUCTURE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
US4745126A (en) *	1987-03-12	1988-05-17	Eli Lilly And Company	Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
US4943428A (en) *	1987-07-10	1990-07-24	Wright State University	Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3809155A1 (en) *	1988-03-18	1989-09-28	Bayer Ag	1,3,4,5-TETRAHYDROBENZ- (C, D) indoles
GB8824744D0 (en) *	1988-10-21	1988-11-30	Erba Carlo Spa	Antiemesis ergoline derivatives
US5204340A (en) *	1989-04-11	1993-04-20	Eli Lilly And Company	Tetrahydrobenz(c,d)indole serotonin agonists
US4977172A (en) *	1989-09-29	1990-12-11	Warner-Lambert Company	Method of treating the symptoms of cognitive decline in an elderly patient employing (S)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)-methyl]-2-oxazolidinone
TW219933B (en) *	1990-02-26	1994-02-01	Lilly Co Eli
US5212319A (en) *	1990-02-26	1993-05-18	Eli Lilly And Company	Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor
US5039820A (en) *	1990-02-26	1991-08-13	Eli Lilly And Company	4-amino-6-iodo-hexahydrobenz(cd)indoles
US5302612A (en) *	1990-02-26	1994-04-12	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
US5397779A (en) *	1990-06-15	1995-03-14	Roussel-Uclaf	Cephalosporins
US5229410A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
US5627199A (en) *	1991-03-28	1997-05-06	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz [CD] indoles
US5244912A (en) *	1991-03-28	1993-09-14	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5347013A (en) *	1991-03-28	1994-09-13	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5266571A (en) *	1992-01-09	1993-11-30	Amer Moh Samir	Treatment of hemorrhoids with 5-HT2 antagonists

1992
- 1992-09-30 US US07/954,105 patent/US5364856A/en not_active Expired - Fee Related
1993
- 1993-09-27 TW TW082107947A patent/TW248558B/zh active
- 1993-09-27 ZA ZA937153A patent/ZA937153B/en unknown
- 1993-09-27 IL IL10712593A patent/IL107125A/en not_active IP Right Cessation
- 1993-09-27 CA CA002107010A patent/CA2107010A1/en not_active Abandoned
- 1993-09-27 CZ CZ932010A patent/CZ9302010A3/en unknown
- 1993-09-28 KR KR1019930020227A patent/KR940006584A/en not_active Application Discontinuation
- 1993-09-28 MX MX9305998A patent/MX9305998A/en unknown
- 1993-09-28 AU AU48682/93A patent/AU676849B2/en not_active Ceased
- 1993-09-28 HU HU9302749A patent/HUT66076A/en unknown
- 1993-09-29 NO NO933477A patent/NO933477L/en not_active Application Discontinuation
- 1993-09-29 RU RU93054754A patent/RU2138262C1/en active
- 1993-09-29 EP EP99202258A patent/EP1000621A3/en not_active Withdrawn
- 1993-09-29 EP EP93307747A patent/EP0590971A1/en not_active Ceased
- 1993-09-29 CN CN93114191A patent/CN1056144C/en not_active Expired - Fee Related
- 1993-09-29 JP JP5242612A patent/JPH06211655A/en active Pending
1994
- 1994-08-31 US US08/299,175 patent/US5594019A/en not_active Expired - Fee Related
1995
- 1995-05-31 US US08/456,974 patent/US5624944A/en not_active Expired - Fee Related
- 1995-05-31 US US08/454,900 patent/US5665758A/en not_active Expired - Fee Related
- 1995-05-31 US US08/455,431 patent/US5736562A/en not_active Expired - Fee Related
- 1995-05-31 US US08/454,888 patent/US5665743A/en not_active Expired - Fee Related
- 1995-05-31 US US08/454,798 patent/US5750554A/en not_active Expired - Fee Related
- 1995-05-31 US US08/456,256 patent/US5674884A/en not_active Expired - Fee Related
- 1995-05-31 US US08/455,774 patent/US5641797A/en not_active Expired - Fee Related
- 1995-05-31 US US08/456,225 patent/US5643930A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
RU2138262C1 (en)	1999-09-27
NO933477L (en)	1994-04-05
US5643930A (en)	1997-07-01
US5665743A (en)	1997-09-09
CN1094724A (en)	1994-11-09
US5665758A (en)	1997-09-09
AU676849B2 (en)	1997-03-27
HUT66076A (en)	1994-09-28
US5750554A (en)	1998-05-12
HU9302749D0 (en)	1993-12-28
US5641797A (en)	1997-06-24
US5364856A (en)	1994-11-15
CN1056144C (en)	2000-09-06
IL107125A (en)	1998-09-24
EP0590971A1 (en)	1994-04-06
CA2107010A1 (en)	1994-03-31
MX9305998A (en)	1995-01-31
JPH06211655A (en)	1994-08-02
NO933477D0 (en)	1993-09-29
KR940006584A (en)	1994-04-25
US5674884A (en)	1997-10-07
ZA937153B (en)	1995-03-27
US5624944A (en)	1997-04-29
CZ9302010A3 (en)	1994-05-18
AU4868293A (en)	1994-07-14
EP1000621A2 (en)	2000-05-17
US5736562A (en)	1998-04-07
EP1000621A3 (en)	2003-05-14
IL107125A0 (en)	1993-12-28
US5594019A (en)	1997-01-14

Publication	Publication Date	Title
DK0634000T3 (en)	1997-02-24
TW224546B (en)	1994-06-01
DK0598561T3 (en)	1997-03-24
TW242724B (en)	1995-03-11
TW226503B (en)	1994-07-11
BR9304651A (en)	1994-05-10
DK0644844T3 (en)	1997-01-20
BR9207065A (en)	1995-10-24
TW232758B (en)	1994-10-21
BRPI9204323A2 (en)	1994-05-10
IN187007B (en)	2001-12-22
IN185358B (en)	2002-01-06
IN177804B (en)	1997-02-22
AU2098792A (en)	1992-11-12
EP0589259A3 (en)	1994-08-03
EP0560362A3 (en)	1994-01-05
AU640334B1 (en)	1993-08-19
CN3012425S (en)	1992-02-12
CN3013212S (en)	1992-04-15
AU639200B1 (en)	1993-07-15
AU633801B1 (en)	1993-02-04
EP0718224A3 (en)	1996-07-31
AU633800B1 (en)	1993-02-04
AU2619992A (en)	1992-12-17
AU1299692A (en)	1992-08-13