TW202402173A - Plant disease control composition, formulation, and plant disease control method - Google Patents

Abstract

A plant disease control composition containing tebufloquin and an agent for inducing plant resistance as active ingredients.

Description

Plant disease control compositions, preparations and plant disease control methods

The present disclosure relates to plant disease control compositions, preparations and plant disease control methods.

Rice fever is the most harmful disease in rice cultivation caused by Pyricularia oryzae. So far, many control agents using fungicidal compounds have been reported.

In the case of rice fever, many bacteria resistant to existing bactericidal compounds have appeared, and the number of fields where a single bactericidal component cannot achieve sufficient control effect is increasing (Non-Patent Document 1). In addition, compositions using tebufloquin, which is one of the bactericidal components, have been disclosed (for example, Patent Documents 1 to 5). However, the combination of tebufloquin and antibiotics Nothing is disclosed about the mixture of inducers. [Prior Technical Document] 〔Patent documents〕

Patent Document 1: Japanese Patent Application Publication No. 2003-55114 Patent Document 2: International Publication No. 2004/039156 Patent Document 3: International Publication No. 2006/106811 Patent document 4: Japanese Patent Application Publication No. 2011-201858 Patent Document 5: Japanese Patent Application Publication No. 2007-112760 [Non-patent literature]

Non-patent document 1: Latest trends in research on chemical-resistant bacteria and enhanced countermeasures, Journal of the Japan Pesticide Society, Volume 39, Issue 1, Pages 53~57, 2014

[Problem to be solved by the invention]

In view of the above, the demand for fungicides with multiple actions is increasing. Furthermore, as a measure to prevent the occurrence of further fungicide-resistant bacteria, it is known that it is preferable to mix substances with different activities to control plant diseases. Furthermore, from the viewpoint of reducing the environmental load caused by pesticides, it is known that it is preferable to utilize a resistance inducer that is highly effective in controlling plant diseases by improving the resistance inherent in plants.

The problem to be solved by one embodiment of the present disclosure is to provide a plant disease control composition that exhibits an excellent control effect against plant diseases compared with a plant disease control composition containing isobutyroquinol alone as an active ingredient, and to achieve the application of chemicals. A plant disease control composition that reduces dosage and environmental load. Another object of the present disclosure is to provide a preparation using a plant disease control composition and a plant disease control method. [Methods to solve problems]

The inventor of this case discovered that isobutyroquin and a plant resistance inducer will show synergistic plant disease control effects, and completed the present invention. That is, the specific methods used to solve the problem include the following aspects.

(1) A plant disease control composition containing isobutyroquin and a plant resistance inducer as active ingredients. (2) The plant disease control composition as described in (1), wherein the plant disease is rice fever disease. (3) The plant disease control composition as described in (1), wherein the plant resistance inducer contains jasmonic acid, salicylic acid, probenazole, isotianil, and methiozolin (tiadinil), acibenzolar-S-methyl, dichlobentiazox, laminarin, giant knotweed (Reynoutria sachalinensis) extract, Bacillus mycoides isolate J, brewing At least one of the compounds represented by yeast LAS117, fosetyl, phosphorous acid or its salt, and the following formula (I).

[Chemical 1]

In formula (I), _X1 and _X4 each independently represent a hydrogen atom, a fluorine atom, a chlorine atom or a trifluoromethyl group, and _X2 and _X3 each independently represent a hydrogen atom, a fluorine atom, a chlorine atom or a methyl Group, A represents a halogen atom, a hydroxyl group, an amino group, a methylthio group, an alkyl group with 1 to 4 carbon atoms that can be substituted by 1 to 3 halogen atoms, and a carbon number of 1 that can be substituted with 1 to 3 halogen atoms. ~4 alkoxy group, optionally selected from alkylcarbonyl group with 1 to 4 carbon atoms, methoxycarbonyl group, ethoxycarbonyl group, benzylaminocarbonyl group, acetyloxy group, nitro group, cyano group, phenoxy group A phenyl group substituted by 1 to 5 groups in the group consisting of base and benzyl group, B represents an oxygen atom or a sulfur atom, Q represents a divalent group represented by the formula: -NH- or -O-.

(4) A preparation containing the plant disease control composition according to any one of (1) to (3). (5) The preparation described in (4), which is selected from wettable powder, emulsion, flowable agent, granular wettable powder, dry flowable agent, powder, DL powder, FD powder, microcapsule, granule, powder Granules, large granules, carburizing agents and aerosols. (6) A plant disease control method, which involves applying the plant disease control composition according to any one of (1) to (3) to plant diseases. (7) The method for preventing and controlling plant diseases as described in (6), wherein the aforementioned plant disease is rice fever disease. (8) The plant disease control method according to (6) or (7), wherein the application includes at least one of stem and leaf spreading and seedling box treatment. [Effects of the invention]

According to one embodiment of the present disclosure, there is provided a plant disease control composition that exhibits an excellent control effect against plant diseases and reduces the amount of chemical application compared to a plant disease control composition containing isobutyroquinol alone as an active ingredient. , Plant disease control composition that reduces environmental load. According to other embodiments of the present disclosure, preparations and plant disease control methods using a plant disease control composition are provided.

Hereinafter, embodiments of the present disclosure will be described. In addition, these descriptions and examples are provided only for the purpose of illustrating the implementation forms of the present disclosure, and do not limit the scope of the present disclosure.

In this manual, "~" indicating a numerical range is used in the sense of including the numerical values described before and after it as the lower limit and upper limit.

Among the numerical ranges described in stages in this specification, the upper limit or lower limit described in one numerical range may be replaced by the upper limit or lower limit of the numerical range described in other stages. In addition, in the numerical range described in this specification, the upper limit value or the lower limit value of the numerical range can be replaced with the value shown in the Example.

In addition, in this specification, the amount of each component in the object means, when there are multiple substances corresponding to each component in the object, unless otherwise specified, it means the amount of the plurality of substances present in the object. The total content rate or content.

One embodiment of the present disclosure relates to a plant disease control composition containing isobutyroquin and a plant resistance inducer as active ingredients.

The so-called plant resistance inducers here refer to substances that do not show direct antibacterial effects on plant pathogenic bacteria, or show partial antibacterial effects, but their effects are not the main activity against the plant pathogenic bacteria that need to be controlled. If further stated, the so-called plant resistance inducers refer to substances classified as mechanism of action P (inducing resistance in host plants) in the Fungicide Resistance Action Committee (FRAC) in the FRAC code table.

The mechanism by which the plant disease control composition disclosed herein exerts its effect is not necessarily clear, but it is speculated as follows. The plant disease control composition disclosed in the present disclosure has a bactericidal effect and a resistance-inducing effect by combining a fungicide that cannot achieve sufficient control effect on plant diseases under a single case with a compound having different effects. The synergistic effect can effectively prevent plant diseases represented by rice fever, and can reduce the number of times of dispersion of pesticides with bactericidal effects. In addition, the plant disease control composition disclosed in the present disclosure can reduce the risk of occurrence of fungicide-resistant bacteria. In addition, the plant disease control composition disclosed in the present disclosure can also reduce the amount of fungicide application in each farming period, thereby reducing environmental load.

The plant disease control composition disclosed herein will make a huge contribution to the stabilization of agricultural production and environmental protection.

As for the plant resistance inducer in the present disclosure, examples include: jasmonic acid, salicylic acid, culling fever, azidine, thiazofen, benzene-S-methyl, diclofenthiazole, Laminaria polysaccharide, giant knotweed extract, Bacillus mycoides isolate J, Saccharomyces cerevisiae LAS117, forsaid, phosphorous acid or its salt, and compounds represented by the following formula (I), but are not limited thereto.

[Chemicalization 2]

In formula (I), _X1 and _X4 each independently represent a hydrogen atom, a fluorine atom, a chlorine atom or a trifluoromethyl group, and _X2 and _X3 each independently represent a hydrogen atom, a fluorine atom, a chlorine atom or a methyl Group, A represents a halogen atom, a hydroxyl group, an amino group, a methylthio group, an alkyl group with 1 to 4 carbon atoms that can be substituted by 1 to 3 halogen atoms, and a carbon number of 1 that can be substituted with 1 to 3 halogen atoms. ~4 alkoxy group, optionally selected from alkylcarbonyl group with 1 to 4 carbon atoms, methoxycarbonyl group, ethoxycarbonyl group, benzylaminocarbonyl group, acetyloxy group, nitro group, cyano group, phenoxy group A phenyl group substituted by 1 to 5 groups in the group consisting of base and benzyl group, B represents an oxygen atom or a sulfur atom, Q represents a divalent group represented by the formula: -NH- or -O-.

Specific examples of the compound represented by formula (I) include: 2,6-difluoro-N-(3-methoxyphenyl)-4-pyridylcarbamide (CAS number: 2244744-34- 9. Hereinafter, also referred to as compound A.).

Preferable plant resistance inducers include: culling fever, azitanidin, thiazidin, aracinobenzene-S-methyl, diclofenthiazole, laminarin, and 2,6- Difluoro-N-(3-methoxyphenyl)-4-pyridylcarbamide (CAS number: 2244744-34-9).

The mixing ratio of isobutyroquin and the plant resistance inducer in the plant disease control composition of the present disclosure is preferably in the following range. The plant resistance inducer in combination with isobutyroquin is culling fever, azidine, methiozolin, diclofenthiazole, benzene-S-methyl, or represented by formula (I) In the case of compounds, the mass ratio of the mixed plant resistance inducer is preferably 0.0001 to 10 relative to the isobutyroquinol ratio of 1. Furthermore, the plant resistance inducer in combination with isobutyroquinoline is salicylic acid, jasmonic acid, laminarin, giant knotweed extract, Bacillus mycoides isolate J, Saccharomyces cerevisiae LAS117, Forset, or In the case of phosphorous acid or its salt, the mass ratio of the mixing ratio to isobutyroquinoline is 1, and the combined plant resistance inducer is preferably 0.0001 to 100.

More preferably, according to the mixing ratio of the mass ratio, the plant resistance inducers combined with isobutyroquin are culling fever, azidine, thiazide, diclofenthiazole, and aracinobenzene-S - In the case of a methyl group or a compound represented by formula (I), the combined plant resistance inducer is 0.01 to 10 compared to 1 for isobutylated ethoxyquin. In the case of plants combined with isobutylated ethoxyquin When the resistance inducer is laminarin, the ratio of laminarin is 0.1 to 10 compared to 1 for isobutyroquinol.

Examples of plant pathogens that are targeted to be controlled by the plant disease control composition of the present disclosure include fungi, bacteria, viruses, and the like. However, it is not limited to this. Examples of fungi include phytopathogenic fungi, examples of bacteria include phytopathogenic bacteria, and examples of viruses include phytopathogenic viruses.

Examples of plant pathogenic fungi include: Alternaria alternata, Alternaria kikutiana, Botrytis cinerea, Cochliobolus miyabeanus, and potato anthracnose. (Colletotrichum atramentarium), cucumber anthracnose (Colletotrichum lagenarium), cucumber yellow leaf pathogen (Fusarium oxysporum f. sp. cucumerinum), tomato fusarium wilt (Fusarium oxysporum f. sp. lycopersici), rice leggy fungus (Gibberella fujikuroi), grape night fungus Glomerella cingulata, Pyricularia oryzae, Rhizoctonia solani, Sclerotinia minor, Verticillium albo-atrum ), wheat leaf rust (Puccinia recondita), barley powdery mildew (Erysiphe graminis), potato late blight (Phytophthora infestans), cucumber downy mildew (Pseudoperonospora cubensis), cucumber powdery mildew (Sphaerotheca fuliginea), rice seedling blight (Pythium graminicola), Alternaria solani, Sclerotinia sclerotiorum, Venturia inaequalis, Monilinia fructicola, Colletotrichum gloeosporioides, Cercospora kikuchii, Cercospora beticola, Leptosphaeria nodorum, Blumeria graminis, and Thanatephorus cucumeris (Frank) Donk.

Among the above-mentioned phytopathogenic fungi, the preferred phytopathogenic fungi that are targeted by the plant disease control composition of the present disclosure and are considered to have particularly good effects include: rice flax leaf blight and rice leggy fungi. , Oryzae oryzae, Xanthomonas oryzae, Xanthomonas oryzae, oryzae, oryzae, oryzae, oryzae, oryzae, oryzae, oryzae.

Examples of plant pathogenic bacteria include: Pseudomonas, Erwinia, Pectobacterium, Xanthomonas, Burkholderia Burkholderia, Streptomyces, Ralstonia, Clavibacter, Rhizomonas, Agrobacterium, Bacillus Bacteria of the genus Bacillus, Clostridium, Curtobacterium, Pantoea, Acidovorax, Arthrobacter, and Rhodococcus.

Examples of plant pathogenic viruses include soil-borne wheat mosaic virus, soybean mosaic virus, alfalfa mosaic virus, potato Potato leaf roll virus, Cucumber mosaic virus, Tobacco mosaic virus.

When the plant disease control composition of the present disclosure is used as a preparation, the plant disease control composition of the present disclosure can be used directly. Moreover, the preparation containing the plant disease control composition of this disclosure can also be made into any dosage form according to conventional methods.

The dosage form of the preparation may be wettable powder, emulsion, flowable agent, granular wettable powder, dry flowable agent, powder, DL powder, FD powder, or microcapsule.

The preparation is preferably a pesticide preparation used as a pesticide.

Here, DL powder refers to a preparation that suppresses scattering, has an average particle size of 20 μm or more, and has 20% or less of particles with a particle size of 10 μm or less. In addition, FD powder refers to a preparation utilizing scattering, and the average particle size is 5 μm or less.

The plant disease control composition of the present disclosure can be further used in all preparations such as granules, powder granules, large granules, carburizing agents, and aerosols used in water in Honda and nursery boxes.

These preparations can be produced by adding agricultural and horticultural additives as needed. In terms of additives that are allowed in agriculture and horticulture, they can be listed as: carriers, surfactants, binders, tackifiers, antifreezes, colorants, auxiliaries, etc. Examples of the carrier include solid carriers, liquid carriers, and gaseous carriers. Together with these additives, a pesticide preparation can be produced by a general manufacturing method.

Examples of solid carriers include clays (clay, kaolin, diatomaceous earth, bentonite, acidic clay, etc.), synthetic hydrous silica, talc, perlite, vermiculite, pumice, and other inorganic minerals (silk Micropowders such as mica, quartz, sulfur, activated carbon, calcium carbonate, hydrated silica, titanium oxide, etc.), granular materials, starch, lactose, vinyl chloride polymers, polyurethane and other synthetic polymers, wood powder and other plant-derived materials.

Examples of the liquid carrier include alcohols (methanol, ethanol, isopropyl alcohol, polyethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, glycerin, etc.), ketones (acetone, methyl ethyl ketone, etc.) , Aromatic hydrocarbons (benzyl alcohol, benzene, toluene, xylene, ethylbenzene, methylnaphthalene, etc.), aliphatic hydrocarbons (paraffin, n-hexane, cyclohexane, kerosene, kerosene, etc.), ethers (diethyl naphthalene, etc.) Glycol monoethyl ether, diethylene glycol monomethyl ether, diisopropyl ether, diethyl ether, dihexane, tetrahydrofuran, etc.), esters (propylene carbonate, ethyl acetate, butyl acetate, Benzyl benzoate, isopropyl myristate, fatty acid esters of propylene glycol, etc.), nitriles (acetonitrile, isobutyronitrile, etc.), amides (dimethylformamide, dimethylacetamide, N - Methylpyrrolidone, etc.), halogenated hydrocarbons (methylene chloride, trichloroethane, carbon tetrachloride, etc.), soybean oil, cottonseed oil and other animal and vegetable oils, dimethyl sulfoxide, silicone oil, higher fatty acids, glycerin formal, and water, etc.

Examples of the gaseous carrier include LPG, air, nitrogen, carbon dioxide, dimethyl ether, and the like.

The content of the carrier used in the plant disease control composition of the present disclosure is generally 5 mass% to 99.9 mass% in the plant disease control composition, and preferably 10 mass% to 98 mass%.

Surfactants are used for various purposes such as emulsification, dispersion, penetration, and disintegration. As the surfactant, nonionic surfactants, anionic surfactants, and the like can be used.

As for nonionic surfactants, you can use: polyoxyethylene alkyl ethers, polyoxyethylene styrylphenyl ethers, polyoxyethylene/polyoxypropylene block copolymers, (polyoxyethylene) Sorbitol fatty acid esters, etc. For anionic surfactants, the following can be used: alkyl sulfate esters, alkyl (aryl) sulfonates, naphthalene sulfonic acid/formalin condensates, lignosulfonates, polycarboxylates wait.

The amount of surfactant used in the plant disease control composition of the present disclosure is generally 0.01 mass% to 30 mass% in the plant disease control composition, and preferably 0.05 mass% to 20 mass%.

As the binder, cellulose-based binders such as carboxymethylcellulose salt and methylcellulose, starch-based binders such as polyvinyl alcohol, gum arabic, and dextrin can be used. As the tackifier, organic polymer tackifiers such as xanthan gum, inorganic powders such as bentonite, etc. can be used. As an antifreeze, glycol-based antifreezes such as propylene glycol can be used. As the coloring agent, for example, tar pigments such as Blue No. 1 and Red No. 2, and caramel pigments can be used. Furthermore, auxiliary agents can be added for the purpose of improving the physical properties of the preparation. For example, white carbon to improve fluidity, calcium stearate, isothiazolin-3-one derivatives as antifungal agents, etc. can be used.

In the preparation containing the plant disease control composition of the present disclosure, the content in the preparation is not limited, but the mass part of the plant disease control composition can be appropriately set in the range of 0.01 to 90 parts by mass in 100 parts by mass of the preparation. . The preferred content of the plant disease control composition in the preparation is in the range of 0.1 parts by mass to 50 parts by mass.

The application amount of the plant disease control composition disclosed in the present disclosure is not limited, but can be appropriately set based on disease factors such as weather, environmental conditions, cultivation conditions, growth conditions, application period, application method, and degree of disease in the area targeted for plant disease control. Application amount. As an effective application amount of the plant disease control composition, the application amount can be preferably in the range of 0.01g to 10kg per 10 acres, and more preferably in the range of 1g to 5kg.

The plant disease control composition of the present disclosure can generally be used during the cultivation period of all crops using pesticides, that is, at any period from before sowing to the germination period, seedling raising period, vegetative growth period, and before harvest. A preferable method of using the plant disease control composition of the present disclosure can be used during the cultivation of rice, from post-germination to the seedling stage, field cultivation, and before harvest. The better way to use it is from the seedling stage to just before harvest.

As for the application of the plant disease control composition disclosed in the present disclosure, examples include: stem and leaf spreading treatment on individual plants, seedling box treatment, side strip application using a rice transplanter, water surface application on rice field surface water, and soil surface application. Spreading treatment, soil mixing after spreading treatment on the soil surface, injection treatment into the soil, soil mixing after injection into the soil, soil irrigation treatment, soil mixing after soil irrigation treatment, spray treatment on plant seeds , Application of smearing treatment on plant seeds, application of dipping treatment on plant seeds, application as powder coating on plant seeds, mixing treatment with plant seeds, mixing of fertilizers, etc. Through such applications, plant diseases can be controlled, but the better application methods are stem and leaf spreading and nursery box treatment.

The plant disease control composition disclosed herein is fully effective in preventing plant diseases in any application.

The plant disease control composition of the present disclosure can be further mixed with insecticides, fungicides, acaricides, herbicides and other pest control agents for application. In addition, the plant disease control composition of the present disclosure and the above-mentioned pest control agent can also be applied separately with a time difference.

Examples of the above pesticides include: acephate, dichlorvos, EPN, fenitrothion, fenamifos, prothiofos, profenofos, pyraclofos, chlorpyrifos-methyl, chlorfenvinphos, demeton, ethion, malathion, coumaphos coumaphos), isoxathion, fenthion, diazinon, thiodicarb, aldicarb, oxamyl, propoxur, Carbaryl, fenobucarb, ethiofencarb, fenothiocarb, pirimicarb, carbofuran, carbosulfan, furfuran furathiocarb, hyquincarb, alanycarb, methomyl, benfuracarb, cartap, thiocyclam, freesuda ( bensultap), dicofol, tetradifon, acrinathrin, bifenthrin, cycloprothrin, cyfluthrin, dimefluthrin , empenthrin, fenfluthrin, fenpropathrin, imiprothrin, metofluthrin, permethrin, phenothrin ), resmethrin, tefluthrin, tetramethrin, tralomethrin, transfluthrin, cypermethrin, dimethrin (deltamethrin), cyhalothrin, fenvalerate, fluvalinate, ethofenprox, flufenprox, halfenprox, silfenprox silafluofen), cyromazine, diflubenzuron, teflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron ), novaluron, penfluron, triflumuron, chlorfluazuron, diafenthiuron, methoprene, fenoxycarb , pyriproxyfen, halofenozide, tebufenozide, methoxyfenozide, chromafenozide, dicyclanil, bufenozide buprofezin), hexythiazox, amitraz, chlordimeform, pyridaben, fenpyroxymate, flufenerim, pyrimidifen , tebufenpyrad, tolfenpyrad, fluacrypyrim, acequinocyl, cyflumetofen, flubendiamide, ethiprole, fipronil, ethoxazole, imidacloprid, nitenpyram, clothianidin, acetamiprid, dinotefuran, Thiacloprid, thiamethoxam, pymetrozine, bifenazate, spirodiclofen, spiromesifen, flonicamid, gram Chlorfenapyr, pyriproxyfene, indoxacarb, pyridalyl, spinosad, avermectin, milbemycin ), azadirachtin, nicotine, rotenone, BT bacteria, BT protein, entomopathogenic viruses, emamectin benzoate, spinetoram ,pyrifluquinazon,chlorantraniliprole,cyantraniliprole,cyenopyrafen,spirotetramat,lepimectin,metaflumizone ), pyrafluprole, pyriprole, dimefluthrin, fenazaflor, hydramethylnon, triazamate, diprocycline Ester (afidopyropen), fluoropyrimidine (flupyrimin).

Examples of the above-mentioned fungicides include azoxystrobin, kresoxim-methyl, trifloxystrobin, metominostrobin, orysastrobin, and the like. Strobilurin-based compounds; aniline-pyrimidine-based compounds such as mepanipyrim, pyrimethanil, and cyprodinil; triadimefon, bitertanol ), triflumizole, metconazole, propiconazole, penconazole, flusilazole, myclobutanil, cyproconazole , azole compounds like tebuconazole, hexaconazole, prochloraz, and simeconazole; quinoline compounds like chinomethionate; maneb ), zineb, mancozeb, polycarbamate, propineb-like disulfide carbamate compounds; ethocarb ( phenylcarbamate compounds such as diethofencarb; organochlorine compounds such as chlorothalonil and quintozene; benomyl, methylbutanil thiophanate-methyl), carbendazim-like benzimidazole compounds; metalaxyl, oxadixyl, ofurace, benalaxyl, furalaxyl Phenylamide compounds like furalaxyl and cyprofuram; sulfenic acid compounds like dichlofluanid; cupric hydroxide, oxine-copper Common copper-based compounds; Isoethazole-based compounds such as hydroxyisoxazole; Organophosphorus-based compounds such as fosetyl-aluminium and tolclofos-methyl; Captan ), N-haloalkylthio compounds such as captafol and folpet; dicarboxylates such as procymidone, iprodione and vinclozolin Imine compounds; carboxyaniline compounds such as flutolanil, mepronil, furametpyr, thifluzaide, boscalid, and penthiopyrad Compounds; 𠰌line compounds like fenpropimorph and dimethomorph; organotin compounds like fentin hydroxide and fentin acetate; protectants Cyanopyrrole compounds such as fludioxonil and fenpiclonil, and acceptable acid addition salts of these pesticides.

Furthermore, examples of other fungicide compounds include: tricyclazole, pyroquilon, carpropamid, dicocymet, fenoxanil, heat fthalide, fluazinam, cymoxanil, triforine, pyrifenox, fenarimol, fenpropidin, bencloron ( pencycuron), ferimzone, cyazofamid, iprovalicarb, benthiavalicarb-isopropyl, iminoctadin albesilate, cyflufenamid , kasugamycin, validamycin, streptomycin, oxolinic acid, tebufloquin, isoprothiolane, tolprocarb, pydiflumetofen, picarbutrazox, mandestrobin, dipymetitrone, pyraziflumid , oxathiapiprolin, penflufen, fluoxapiprolin, florylpicoxamid, fluopimomide, ipflufenoquin, fluindane Fluindapyr, isoflucypram, quinofumelin, metyltetraprole, pyridaclomethyl, pyrapropoyne, aminopyrifen ), inpyrfluxam, and acceptable acid addition salts of these pesticides.

Examples of the above-mentioned acaricides include bromopropylate, tetradifon, propargite, amitraz, fenothiocarb, and Hexythiazox, fenbutatin oxide, dienochlor, fenpyroximate, tebufenpyrad, pyridaben, pyrimidifen, kefen clofentezine, etoxazole, halfenprox, milbemectin, acequinocyl, bifenazate, fluacrypyrim, sipifen (spirodichlofen), spiromesifen, chlorfenapyr, Avermectin, cyenopyrafen, and cyflumetofen.

Examples of the herbicides include phenoxy acid compounds such as cyhalofop-butyl and 2,4-D; amines such as esprocarb and desmedipham. Formate compounds; amide compounds such as alachlor and metolachlor; urea compounds such as diuron and tebuthiuron; halosulfuron-methyl Sulfonylurea compounds such as flazasulfuron and flazasulfuron; pyrimidinyloxybenzoic acid compounds such as pyriminobac-methyl; glyphosate, bilanafos, pyriminobac-methyl and other glufosinate), glufosinate ammonium and other amino acid compounds such as glufosinate ammonium salt (glufosinate salt).

The plant disease control composition disclosed herein can also be mixed with plant growth regulators and fertilizers. Furthermore, the plant disease control composition of the present disclosure and the above-mentioned plant growth regulator and fertilizer can also be applied separately with a time difference.

Examples of the above-mentioned plant growth regulators include vinyl agents such as ethephon; growth agents such as indolebutyric acid and ethychlozate; cytokinin agents; gibexin agents ; Auxin antagonist; dwarfing agent; evapotranspiration inhibitor.

Examples of the fertilizer include: nitrogen fertilizers such as urea, ammonium nitrate, ammonium magnesium nitrate, and ammonium chloride; phosphate fertilizers such as superphosphate, ammonium phosphate, magnesium superphosphate, and magnesium phosphate; potassium chloride and potassium bicarbonate. , potassium magnesium nitrate, potassium nitrate, potassium sodium nitrate and other potassium fertilizers; manganese fertilizers such as manganese sulfate, magnesium manganese nitrate and other; boric acid, borate and other boron fertilizers. [Example]

Hereinafter, preparation examples and test examples are given to explain the present disclosure in detail, but the present disclosure is not limited to these preparation examples and test examples.

(Preparation Example 1) Wettable powder 2 mass% isobutyroquinoline, 20 mass% culling heat, 58 mass% clay, 2 mass% white carbon, 13 mass% diatomaceous earth, 4 mass% calcium lignosulfonate, 1% by mass of sodium lauryl sulfate was uniformly mixed and pulverized to obtain a wettable powder.

(Preparation Example 2) Granular wettable powder 2 mass% of isobutyroquinoline, 20 mass% of azidine, 68 mass% of clay, 5 mass% of dextrin, 4 mass% of alkyl maleic acid copolymer, 1 mass% of laurel Sodium sulfate is uniformly mixed and pulverized, water is added and fully kneaded, and then granulated and dried to obtain granular wettable powder.

(Preparation Example 3) Flow agent Mix 3% by mass of isobutyroquinoline, 30% by mass of diclofenthiazole, 5% by mass of polyoxyethylene styrylphenyl ether sulfate, 6% by mass of propylene glycol, 1% by mass of bentonite, After mixing 0.05% by mass of silicone defoaming agent (trade name: PRONAL EX-300, Toho Chemical Industry Co., Ltd.) and 0.02% by mass of antifungal agent (trade name: Biohope L, KI Chemicals Co., Ltd.), Add appropriate amount of water and grind using wet grinder. After that, 3% by mass of a 1% aqueous solution of xanthan gum and the remaining amount of water were added to 100% by mass to obtain a flow agent.

(Preparation Example 4) Emulsion 9.2 mass% of isobutyroquinoline, 5.8 mass% of 2,6-difluoro-N-(3-methoxyphenyl)-4-pyridylcarbamide (compound A), 20 mass% of N,N-dimethylformamide, 55% by mass of aromatic solvent (trade name: T-SOL 150, T-SOL Co., Ltd.), 10% by mass of polyoxyethylene alkyl aryl ether Mix and dissolve to obtain an emulsion.

(Preparation Example 5) Dry flow agent 10% by mass of isobutyroquinoline, 10% by mass of aracinated benzene-S-methyl, 65% by mass of kaolin, 5% by mass of dextrin, and 5% by mass of alkyl maleic acid copolymer , 5 mass% sodium lauryl sulfate are uniformly mixed and pulverized, water is added and fully kneaded, and then granulated and dried to obtain a dry flow agent.

(Preparation Example 6) Powder 0.5% by mass of isobutyroquin, 5.0% by mass of methiostrobin, 57.5% by mass of clay, 36% by mass of talc, and 1% by mass of calcium stearate were uniformly mixed to obtain a powder.

(Preparation Example 7) DL powder 1 mass% of isobutyroquinoline, 1 mass% of laminarin, 95.5 mass% of DL clay (trade name: Showa DL clay, Showa KDE Co., Ltd.), 2 mass% of white carbon, 0.5 mass% of light liquid paraffin are evenly mixed to obtain DL powder.

(Test Example 1) Preventive spread treatment for rice fever In the test solution, isobutyroquin and each of the resistance inducers described in Table 1 were dissolved in acetone. This acetone solution was diluted with water so as to have the concentration described in Table 1, and 1/1,000 volume of a spreading agent (Neostelin, manufactured by Combin Chemical Industry Co., Ltd.) was added to prepare a spreading liquid.

Plant 8 to 10 seeds of rice (variety: Juishoku) in a small pot with a diameter of 3 cm, and cultivate it using cultivation soil in a greenhouse. Spread 2 mL of the dispersion liquid prepared as above on the seedlings at the 2-leaf stage or 3-leaf stage, and dry naturally.

On the other hand, conidia of rice fever fungus (Pyricularia oryzae) cultured on an agar medium are suspended at a concentration of 1×10 ⁵ /mL to 5×10 ⁵ /mL. In this suspension, a solution of Tween 20 diluted 4000 times with deionized water was used. The rice fever conidia suspension was spray-inoculated onto rice and allowed to infect for 24 hours in a dark humid room. After that, rice is cultivated in a greenhouse at 25°C/18°C day and night, and the control value is calculated using the following mathematical formula based on the number of rice fever lesions that develop on rice leaves 7 to 9 days after inoculation. Then, use the following Colby's equation to test whether there is a synergistic effect.

Control value = ((number of lesions in the untreated area - number of lesions in the treated area) / number of lesions in the untreated area) × 100

(Colby's formula) Theoretical value=(control value A+control value B)-(control value A×control value B)/100

In the results shown in Table 1 below, the actual control value is higher than Colby's theoretical value, confirming the synergistic effect.

[Table 1]

(Test Example 2) Long-term control effect on rice fever For the test solution, isobutyroquinoline and compound A were dissolved in acetone respectively. This acetone solution was diluted with water so as to have the concentration described in Table 2, and 1/1,000 volume of a spreading agent (Neostelin, manufactured by Combin Chemical Industry Co., Ltd.) was added to prepare a spreading liquid. 15 g of rice (variety: Jushi) seeds were sown in a small trough of 30 cm × 20 cm, and cultivated in a greenhouse at 25°C/18°C day and night.

On the other hand, conidia of rice fever fungus (Pyricularia oryzae) cultured on an agar medium are suspended at a concentration of 1×10 ⁴ /mL to 5×10 ⁴ /mL. In this suspension, a solution of Tween 20 diluted 4000 times with deionized water was used. The rice fever conidia suspension was spray-inoculated onto 2-leaf stage rice seedlings, and infected in a dark humid room for 24 hours. Afterwards, rice seedlings were cultivated in a greenhouse, and rice fever lesions were confirmed on rice leaves 7 to 9 days after inoculation. Spread 12 mL of the above-mentioned dispersion liquid and let it dry naturally indoors. After that, it was left to stand for 24 hours in a humid chamber (temperature: 25°C, humidity: 100%), and the rice fever bacteria were naturally infected in the tank. After another week, the animals were allowed to naturally infect for 24 hours in the same manner. After that, the rice seedlings were cultivated in a greenhouse set at 25°C/18°C day and night for 7 to 9 days, and the number of rice fever lesions formed on the spread uppermost leaves of 50 randomly selected seedlings was measured. . Based on the number of lesions obtained, the control value is calculated using the following mathematical formula. Then, use Colby's algorithm to test whether there is a synergistic effect.

Control value = ((number of lesions in the untreated area - number of lesions in the treated area) / number of lesions in the untreated area) × 100

(Colby's theoretical formula) Theoretical value=(control value A+control value B)-(control value A×control value B)/100

In the results shown in Table 2 below, the actual control value was significantly higher than Colby's theoretical value, confirming the synergistic effect.

[Table 2] [Industrial availability]

The plant disease control composition disclosed in the present invention has an excellent control effect against rice fever and reduces the risk of drug-resistant bacteria, and is a useful composition for agricultural use.

The disclosure of Japanese Patent Application No. 2022-052593 filed on March 28, 2022 is incorporated into this specification in its entirety by reference. Furthermore, all documents, patent applications, and technical standards described in this specification are hereby incorporated by reference to the same extent as if each individual document, patent application, or technical standard was specifically and individually indicated to be incorporated by reference. in the manual.

Claims (8)

A plant disease control composition contains tebufloquin and a plant resistance inducer as active ingredients. For example, the plant disease control composition of claim 1, wherein the plant disease is rice fever disease. Such as the plant disease control composition of claim 1, wherein the plant resistance inducer contains jasmonic acid, salicylic acid, probenazole, isotianil, tiadinil, Acibenzolar-S-methyl, dichlobentiazox, laminarin, Reynoutria sachalinensis extract, Bacillus mycoides isolate J, Saccharomyces cerevisiae LAS117, Fu At least one of fosetyl, phosphorous acid or its salt, and the compound represented by the following formula (I); [Chemical 1] In formula (I), _X1 and _X4 each independently represent a hydrogen atom, a fluorine atom, a chlorine atom or a trifluoromethyl group, and _X2 and _X3 each independently represent a hydrogen atom, a fluorine atom, a chlorine atom or a methyl Group, A represents a halogen atom, a hydroxyl group, an amino group, a methylthio group, an alkyl group with 1 to 4 carbon atoms that can be substituted by 1 to 3 halogen atoms, and a carbon number of 1 that can be substituted with 1 to 3 halogen atoms. ~4 alkoxy group, optionally selected from alkylcarbonyl group with 1 to 4 carbon atoms, methoxycarbonyl group, ethoxycarbonyl group, benzylaminocarbonyl group, acetyloxy group, nitro group, cyano group, phenoxy group A phenyl group substituted by 1 to 5 groups in the group consisting of base and benzyl group, B represents an oxygen atom or a sulfur atom, Q represents a divalent group represented by the formula: -NH- or -O-. A preparation containing the plant disease control composition according to any one of claims 1 to 3. Such as the preparation of claim 4, which is selected from the group consisting of wettable powder, emulsion, flowable agent, granular wettable powder, dry flowable agent, dust, DL powder, FD powder, microcapsule, granule, granule, large Granules, carburizing agents and aerosols. A plant disease control method, which applies the plant disease control composition according to any one of claims 1 to 3 to plant diseases. For example, claim the method for preventing and controlling plant diseases in item 6, wherein the plant disease is rice fever disease. The plant disease control method of claim 6 or 7, wherein the application includes at least one of stem and leaf spreading and seedling box treatment.