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TW201924734A - Apparatus that vaporizes substance, vaporizer system, method excuted by vaporizer system, and vapor-theraphy device - Google Patents

Apparatus that vaporizes substance, vaporizer system, method excuted by vaporizer system, and vapor-theraphy device Download PDF

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TW201924734A
TW201924734A TW106141497A TW106141497A TW201924734A TW 201924734 A TW201924734 A TW 201924734A TW 106141497 A TW106141497 A TW 106141497A TW 106141497 A TW106141497 A TW 106141497A TW 201924734 A TW201924734 A TW 201924734A
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substance
gas
user
chamber
controller
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TW106141497A
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TWI781968B (en
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欣榮 梅
端豪 張
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香港商麗年控股有限公司
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Abstract

An apparatus that vaporizes a substance. The apparatus comprises a pod and a vaporizing device that removably connects to the pod. The pod includes a unique identification number and stores the substance to be vaporized and a carrier of the substance. The vaporizing device includes a memory that stores unique identification numbers and temperatures for each of the unique identification numbers, a reader that reads the unique identification number of the pod, and a controller that selects one of temperatures assigned to the unique identification number from the memory, and a heating element that heats the substance and the carrier to the one of the temperatures to vaporize the substance into a vapor for inhalation to a user.

Description

汽化物質的設備、汽化器系統、由汽化器系統執行的方法、以 及氣體治療裝置 Apparatus for vaporizing a substance, a vaporizer system, a method performed by a vaporizer system, And gas therapy device

本發明涉及用於汽化待被使用者吸入的物質的方法和設備。 The present invention relates to a method and apparatus for vaporizing a substance to be inhaled by a user.

藥物可以通過醫用吸入器或氣霧劑治療裝置通過吸入直接輸送到患者的肺部。例如,藥物可被汽化器汽化以將藥物的活性成分輸送給患者。在用戶的鼻道和呼吸道中的藥物輸送或藥物吸收的效率是一個關鍵因素。 The drug can be delivered directly to the patient's lungs by inhalation via a medical inhaler or aerosol treatment device. For example, the drug can be vaporized by a vaporizer to deliver the active ingredient of the drug to the patient. The efficiency of drug delivery or drug absorption in the user's nasal passages and respiratory tract is a key factor.

提供高效、方便和安全的通過汽化輸送藥物的途徑的新方法和系統將有助提高技術需求,解決技術問題。 New methods and systems that provide efficient, convenient, and safe ways to deliver drugs by vaporization will help increase technology requirements and solve technical problems.

一個示例性實施例是一種汽化物質的設備。所述設備包括容器和可拆卸地連接到所述容器的汽化裝置。所述容器包括唯一標記號,並儲存待汽化的物質和物質的載體。汽化裝置包括儲存唯一標記號和每個唯一標記號的溫度的記憶體、讀取所述容器的唯一標記號的讀取器、從記憶體選擇分配給唯一標記號的溫度之一的控制器,以及加熱元件,所述加熱元件 將物質和載體加熱至將物質汽化成氣體以供使用者吸入的溫度之一。 An exemplary embodiment is an apparatus for vaporizing a substance. The apparatus includes a container and a vaporization device detachably coupled to the container. The container includes a unique marking number and stores a carrier of the substance and substance to be vaporized. The vaporization device includes a memory that stores a unique mark number and a temperature of each unique mark number, a reader that reads a unique mark number of the container, and a controller that selects one of temperatures assigned to the unique mark number from the memory, And a heating element, the heating element The substance and carrier are heated to one of the temperatures at which the substance is vaporized into a gas for inhalation by the user.

在本文中討論了其他示例性實施例。 Other exemplary embodiments are discussed herein.

100‧‧‧設備 100‧‧‧ Equipment

110‧‧‧容器 110‧‧‧ container

120‧‧‧汽化裝置 120‧‧‧Vaporization unit

122‧‧‧記憶體 122‧‧‧ memory

124‧‧‧讀取器 124‧‧‧Reader

126‧‧‧控制器 126‧‧‧ Controller

128‧‧‧加熱元件 128‧‧‧ heating element

129‧‧‧顯示器 129‧‧‧ display

200‧‧‧汽化器系統 200‧‧‧Vaporizer system

210‧‧‧罐 210‧‧‧ cans

220‧‧‧汽化裝置 220‧‧‧Vaporization unit

222‧‧‧電源按鈕 222‧‧‧Power button

224‧‧‧電源連接器 224‧‧‧Power connector

230‧‧‧面罩 230‧‧‧ mask

250‧‧‧汽化器系統 250‧‧‧Vaporizer system

300‧‧‧汽化器系統 300‧‧‧Vaporizer system

310‧‧‧罐(或容器) 310‧‧‧ cans (or containers)

320‧‧‧汽化裝置 320‧‧‧Vaporization unit

322‧‧‧金屬表面 322‧‧‧Metal surface

324‧‧‧加熱元件 324‧‧‧ heating element

326‧‧‧溫度計 326‧‧‧ thermometer

330‧‧‧面罩(或嘴件或鼻件) 330‧‧‧ mask (or mouthpiece or nose piece)

332‧‧‧分隔件 332‧‧‧Parts

334‧‧‧輸入腔室 334‧‧‧Input chamber

336‧‧‧輸出腔室 336‧‧‧Output chamber

410~440‧‧‧方框 410~440‧‧‧Box

500‧‧‧氣體治療裝置 500‧‧‧ gas therapy device

510‧‧‧金屬容器 510‧‧‧Metal containers

520‧‧‧主體 520‧‧‧ Subject

522‧‧‧加熱器 522‧‧‧heater

524‧‧‧控制器 524‧‧‧ Controller

530‧‧‧嘴件 530‧‧‧ mouthpiece

532‧‧‧腔室 532‧‧ ‧ chamber

534‧‧‧腔室入口 534‧‧‧Centre entrance

536‧‧‧腔室出口 536‧‧‧room exit

600‧‧‧曲線(圖) 600‧‧‧ Curve (Figure)

圖1示出了根據示例性實施例的用於汽化的設備的方塊圖。 FIG. 1 shows a block diagram of an apparatus for vaporization, according to an exemplary embodiment.

圖2示出了根據示例性實施例的汽化器系統。 FIG. 2 illustrates a vaporizer system in accordance with an exemplary embodiment.

圖3示出了根據另一示例性實施例的汽化器系統的局部剖視圖。 FIG. 3 illustrates a partial cross-sectional view of a vaporizer system in accordance with another exemplary embodiment.

圖4示出了根據另一示例性實施例的向使用者提供汽化物質的方法。 FIG. 4 illustrates a method of providing a vaporized material to a user in accordance with another exemplary embodiment.

圖5示出了根據示例性實施例的氣體治療裝置的方塊圖。 FIG. 5 shows a block diagram of a gas treatment device in accordance with an exemplary embodiment.

圖6示出了根據示例性實施例的隨著時間的吸入壓力的曲線圖。 FIG. 6 shows a graph of suction pressure over time, according to an exemplary embodiment.

示例性實施例涉及通過將物質汽化以供使用者吸入而將來自藥物的活性成分或物質輸送到使用者的設備和方法。 An exemplary embodiment relates to an apparatus and method for delivering an active ingredient or substance from a drug to a user by vaporizing the substance for inhalation by a user.

煎煮中藥(TCM)是耗時的過程。從TCM煎煮出多種成份的傳統方法是煮沸,其採用以經驗為依據的配方,並需要長時間的加熱過程。 Decoction of traditional Chinese medicine (TCM) is a time consuming process. The traditional method of boiling a variety of ingredients from TCM is boiling, which uses an experience-based formulation and requires a long heating process.

煎煮的另一種方法是使用噴霧器作為氣霧劑治療裝置。大部分用於氣霧劑治療的油基精華都是通過超音波噴霧 器來輸送的。然而,霧化不是有效的,因為它會輸送水滴,而且待輸送給使用者的物質會懸浮在霧中。由於液滴、重量和疏水性質,大量的物質沿著輸送路徑沉降,無法到達目的地。 Another method of boiling is to use a nebulizer as an aerosol treatment device. Most oil-based essences for aerosol treatment are sprayed by ultrasonic waves. To deliver. However, atomization is not effective because it transports water droplets and the material to be delivered to the user is suspended in the mist. Due to droplets, weight and hydrophobic properties, a large amount of material settles along the transport path and cannot reach its destination.

示例性實施例解決了這些問題,並提供了一種高效且方便的方法,通過汽化器系統經由鼻道和呼吸道輸送汽化物質。汽化物質採用較短的路徑到達其目的地;例如,如果應用在鼻道的話,一些用於神經疾病和用於肺部疾病的藥物將採用捷徑。 The exemplary embodiments address these issues and provide an efficient and convenient method of delivering vaporized material through the nasal passages and respiratory passages through a vaporizer system. Vaporized substances use a shorter path to their destination; for example, if applied to the nasal passages, some drugs for neurological diseases and for lung diseases will use shortcuts.

例如,在一個實施例中,從TCM或其他藥物提取的液態油基精華用基於環糊精的載體配製。將所配製的物質密封在容器或膠囊中。包裝在容器中的物質被汽化器系統中的加熱元件加熱並被汽化以供使用者吸入。汽化器系統允許向使用者輸送精確量的氣體。 For example, in one embodiment, liquid oil-based extracts extracted from TCM or other drugs are formulated with a cyclodextrin-based carrier. The formulated material is sealed in a container or capsule. The material packaged in the container is heated by the heating element in the vaporizer system and vaporized for inhalation by the user. The carburetor system allows a precise amount of gas to be delivered to the user.

例如,在一個實施例中,用於汽化的設備包括容器和可拆卸地連接到所述容器的汽化裝置。容器儲存待汽化的物質和所述物質的載體。進一步用唯一標記號標記容器,例如相應於所包裝的物質和其載體的成分和劑量的射頻識別(RFID)號。 For example, in one embodiment, an apparatus for vaporization includes a container and a vaporization device detachably coupled to the container. The container stores the substance to be vaporized and the carrier of the substance. The container is further labeled with a unique indicia, such as a radio frequency identification (RFID) number corresponding to the composition and dosage of the packaged substance and its carrier.

汽化裝置包括記憶體,其儲存唯一標記號和每個唯一標記號的溫度。包裝在容器中的不同物質和其載體具有不同的汽化目標溫度。 The vaporization device includes a memory that stores a unique tag number and a temperature for each unique tag number. The different materials packaged in the container and their carriers have different vaporization target temperatures.

汽化裝置還包括讀取器,其讀取容器的唯一標記號,並將讀取結果發送給汽化裝置的控制器。控制器從記憶體中選擇分配給唯一標記號的溫度之一,並命令加熱元件將容器 加熱至被選擇為將物質汽化成氣體以供使用者吸入的溫度。 The vaporizer also includes a reader that reads the unique tag number of the container and sends the result of the reading to the controller of the vaporizer. The controller selects one of the temperatures assigned to the unique tag number from the memory and commands the heating element to place the container Heating to a temperature selected to vaporize the material into a gas for inhalation by the user.

例如,在一個實施例中,汽化裝置還包括溫度計,其檢測容器的溫度。汽化裝置的溫度控制單元基於溫度計所檢測的容器溫度來調節加熱元件的功率。 For example, in one embodiment, the vaporization device also includes a thermometer that detects the temperature of the container. The temperature control unit of the vaporizer adjusts the power of the heating element based on the temperature of the vessel detected by the thermometer.

例如,在一個實施例中,汽化裝置還包括壓力感測器,其檢測容器內的氣體的氣體壓。當所檢測的氣體壓在預定的壓力範圍之外時,控制器關閉汽化裝置。 For example, in one embodiment, the vaporization device further includes a pressure sensor that detects the gas pressure of the gas within the container. The controller turns off the vaporization device when the detected gas pressure is outside of the predetermined pressure range.

例如,在一個實施例中,汽化裝置還包括感測使用者的呼吸頻率的感測器,以及控制使用者吸入的氣體的流量的閥。所述閥由汽化裝置的控制器以與使用者的呼吸頻率同步的頻率開啟和關閉。作為一個示例,汽化裝置的閥和加熱元件由控制器同時開啟和關閉。 For example, in one embodiment, the vaporization device further includes a sensor that senses the respiratory rate of the user, and a valve that controls the flow of gas inhaled by the user. The valve is opened and closed by a controller of the vaporization device at a frequency synchronized with the user's respiratory rate. As an example, the valve and heating element of the vaporizer are simultaneously turned on and off by the controller.

為了增強藥物的輸送效率和吸收,將電荷添加到目標物質或汽化物質的流動通道中。作為一個示例,電離單元設置在物質的氣體的通道。該單元以正或負電荷離子化氣體以增強使用者對物質的吸收。 In order to enhance the delivery efficiency and absorption of the drug, a charge is added to the flow channel of the target substance or vaporized substance. As an example, the ionization unit is arranged in the passage of the gas of the substance. The unit ionizes the gas with a positive or negative charge to enhance the user's absorption of the material.

示例性實施例涉及汽化器系統,其具有包括腔室的罐、可拆卸地連接到所述罐的汽化裝置和可拆卸地連接到所述罐的腔室的面罩。 An exemplary embodiment relates to a vaporizer system having a canister including a chamber, a vaporization device detachably coupled to the canister, and a mask removably coupled to the chamber of the canister.

所述罐的腔室容納一個或多個填充有液體物質的膠囊,所述液體物質用基於環糊精的載體配製以用於汽化。所述載體是承載油基和水基物質的兩親性載體。 The chamber of the canister contains one or more capsules filled with a liquid substance that is formulated with a cyclodextrin-based carrier for vaporization. The carrier is an amphiphilic carrier that carries an oil-based and water-based substance.

汽化裝置包括加熱元件,其將液體物質加熱至目標溫度以將液體物質汽化成氣體。物質和物質的載體被配製成 能夠在低於100℃下有效地汽化以減少有害物質的產生。 The vaporization device includes a heating element that heats the liquid material to a target temperature to vaporize the liquid material into a gas. The carrier of matter and substance is formulated It can be effectively vaporized at less than 100 ° C to reduce the generation of harmful substances.

物質和物質的載體被配製成以4至10μm的粒徑汽化。4至10μm的粒徑為可吸入尺寸,但大於可呼出尺寸,進一步提高了將物質輸送到使用者的效率。 The carrier of the substance and substance is formulated to be vaporized at a particle size of 4 to 10 μm. A particle size of 4 to 10 μm is respirable, but larger than the exhalable size, further improving the efficiency of delivering the substance to the user.

汽化器系統的面罩具有空氣入口和空氣出口,在所述空氣入口中,來自腔室的氣體流向使用者,在所述空氣出口中,使用者呼氣。例如,嘴件或鼻件提供空氣入口和出口路徑。通過將吸入路徑限制在鼻道和將呼氣路徑限制在口部,將吸入迴圈與呼氣迴圈分開。使用者通過口部或鼻吸入汽化物質。嘴件和鼻件是可互換的。汽化器系統可通過不同的延伸部分將汽化物質經由鼻或口部輸送到用戶。 The mask of the carburetor system has an air inlet and an air outlet in which gas from the chamber flows to a user where the user exhales. For example, the mouthpiece or nosepiece provides an air inlet and outlet path. The suction loop is separated from the expiratory loop by confining the inhalation path to the nasal passage and restricting the expiratory path to the mouth. The user inhales vaporized material through the mouth or nose. The mouthpiece and nose piece are interchangeable. The vaporizer system can deliver vaporized material to the user via the nose or mouth through different extensions.

例如,在一個實施例中,汽化器系統還包括流量計以計算由使用者吸入的氣體的體積。汽化器系統基於由使用者吸入的氣體的體積來計算由使用者吸入的物質的消耗劑量,並將由使用者吸入的物質的消耗劑量記錄在汽化器系統的記憶體中或遠端伺服器。 For example, in one embodiment, the vaporizer system also includes a flow meter to calculate the volume of gas inhaled by the user. The carburetor system calculates the consumed dose of the substance inhaled by the user based on the volume of gas inhaled by the user, and records the consumed dose of the substance inhaled by the user in the memory of the vaporizer system or the remote server.

圖1示出了用於汽化的設備100的方塊圖。設備100包括容器110和汽化裝置120。汽化裝置120包括記憶體122、讀取器124、控制器126、加熱元件128,以及顯示器129。 FIG. 1 shows a block diagram of an apparatus 100 for vaporization. Apparatus 100 includes a vessel 110 and a vaporizer 120. The vaporizer 120 includes a memory 122, a reader 124, a controller 126, a heating element 128, and a display 129.

作為示例,容器110儲存待汽化的物質和物質的載體。所述載體是水基的,具有親水和疏水性質,以承載油基和水溶膠物質。進一步用唯一標記號標記容器,例如相應於所包裝的物質和其載體的成分和劑量的射頻識別(RFID)或QR碼。 As an example, the container 110 stores a carrier of the substance and substance to be vaporized. The carrier is water based and has hydrophilic and hydrophobic properties to carry oil based and hydrosol materials. The container is further labeled with a unique indicia, such as a radio frequency identification (RFID) or QR code corresponding to the composition and dosage of the packaged substance and its carrier.

汽化裝置120可拆卸地連接到容器110,並包括記 憶體122,其儲存唯一標記號和每個唯一標記號的溫度。包裝在容器中的物質和其載體的每種組合都具有汽化溫度,並且容器具有唯一標記號,其反映儲存在容器中的物質和載體的組合的汽化溫度。 The vaporizer 120 is detachably coupled to the container 110 and includes a record Recalling body 122, which stores the unique tag number and the temperature of each unique tag number. Each combination of the substance packaged in the container and its carrier has a vaporization temperature, and the container has a unique marking number that reflects the vaporization temperature of the combination of the substance and the carrier stored in the container.

作為示例,從天然桉樹油中提取三種生物物質:桉葉油醇、蒎烯和檸檬烯。這些生物物質是疏水的,這意味著它們不是水溶性的。這些疏水物質被配製成包括環糊精的溶劑或載體。環糊精具有低於100℃的汽化溫度,並將桉樹油的汽化溫度從~200℃降至低於100℃。環糊精還用作載體以通過其疏水腔承載所述三種疏水物質。 As an example, three biological substances are extracted from natural eucalyptus oil: eucalyptol, terpene and limonene. These biological substances are hydrophobic, which means that they are not water soluble. These hydrophobic substances are formulated into a solvent or carrier including a cyclodextrin. The cyclodextrin has a vaporization temperature below 100 ° C and reduces the vaporization temperature of the eucalyptus oil from ~200 ° C to below 100 ° C. The cyclodextrin also acts as a carrier to carry the three hydrophobic materials through its hydrophobic cavity.

當容器與汽化裝置連接時,汽化裝置120的讀取器124讀取容器的唯一標記號。控制器126具有溫度控制單元,其接收從讀取器發送的容器的唯一標記號。然後,溫度控制單元從記憶體中選擇分配給唯一標記號的溫度之一,並命令加熱元件128將容器加熱至被選擇為將物質汽化成氣體以供使用者吸入的溫度。作為示例,加熱元件可以嵌入到汽化裝置的主體中或構建在容器內。加熱元件包括正溫度係數熱敏電阻以保持目標溫度。 When the container is connected to the vaporizer, the reader 124 of the vaporizer 120 reads the unique marker number of the container. The controller 126 has a temperature control unit that receives the unique tag number of the container sent from the reader. The temperature control unit then selects one of the temperatures assigned to the unique tag number from the memory and commands the heating element 128 to heat the container to a temperature selected to vaporize the material into a gas for inhalation by the user. As an example, the heating element can be embedded in the body of the vaporization device or built into the container. The heating element includes a positive temperature coefficient thermistor to maintain the target temperature.

汽化裝置120的顯示器129顯示與汽化裝置的各種元件的狀態有關的資訊,例如待汽化物質的類型、汽化溫度,以及汽化裝置的可充電電池的電池狀態。 Display 129 of vaporization device 120 displays information relating to the status of various components of the vaporization device, such as the type of material to be vaporized, the vaporization temperature, and the battery state of the rechargeable battery of the vaporization device.

圖2示出了根據示例性實施例的汽化器系統200。汽化器系統200包括具有腔室的罐210、可拆卸地連接到所述罐的汽化裝置220,以及可拆卸地連接到罐210的腔室的面罩 230。 FIG. 2 shows a vaporizer system 200 in accordance with an exemplary embodiment. The carburetor system 200 includes a canister 210 having a chamber, a vaporizer 220 detachably coupled to the canister, and a mask detachably coupled to the chamber of the canister 210 230.

罐210的腔室容納一個或多個填充有液體物質的膠囊,所述液體物質用基於環糊精的載體配製以用於汽化。所述載體是承載油基和水基物質的兩親性載體。物質和物質的載體被配製成能夠在低於100℃的溫度下有效地汽化以減少有害物質的產生。 The chamber of tank 210 contains one or more capsules filled with a liquid substance that is formulated with a cyclodextrin-based carrier for vaporization. The carrier is an amphiphilic carrier that carries an oil-based and water-based substance. The carrier of the substance and substance is formulated to be effective to vaporize at temperatures below 100 ° C to reduce the production of harmful substances.

汽化裝置220具有電源按鈕222和電源連接器224。電源按鈕222允許使用者手動開關汽化裝置。電源連接器224對汽化裝置的可充電電池充電或連接汽化裝置與電源插座。作為一個示例,汽化裝置包括操作鍵,讓使用者手動設定諸如加熱溫度和持續時間等參數。汽化裝置還包括LED指示器或報警蜂鳴器。 The vaporizer 220 has a power button 222 and a power connector 224. The power button 222 allows the user to manually switch the vaporizer. The power connector 224 charges the rechargeable battery of the vaporizer or connects the vaporizer to the power outlet. As an example, the vaporization device includes an operating button that allows the user to manually set parameters such as heating temperature and duration. The vaporizer also includes an LED indicator or an alarm buzzer.

汽化裝置220包括加熱元件(未在圖2示出),其將膠囊中的液體物質加熱至目標溫度以將液體物質汽化成氣體。作為示例,芯元件連接加熱元件與所述罐的腔室中的膠囊,以將熱量從加熱元件轉移到膠囊中的液體物質,並將液體物質汽化成氣體以供使用者吸入。 The vaporizer 220 includes a heating element (not shown in Figure 2) that heats the liquid material in the capsule to a target temperature to vaporize the liquid material into a gas. By way of example, the core element connects the heating element to the capsule in the chamber of the can to transfer heat from the heating element to the liquid material in the capsule and vaporize the liquid material into a gas for inhalation by the user.

液體物質和物質的載體被配製成汽化為4至10μm的粒徑。4至10μm的粒徑為可吸入尺寸,但大於可呼出尺寸,提高了將物質輸送到使用者的效率。 The carrier of the liquid substance and substance is formulated to have a particle size of vaporized to 4 to 10 μm. A particle size of 4 to 10 μm is respirable, but larger than the exhalable size, improving the efficiency of delivering the substance to the user.

汽化器系統的面罩230具有空氣入口和空氣出口,在所述空氣入口中,來自腔室的氣體流向使用者,在所述空氣出口中,使用者呼氣。例如,嘴件或鼻件提供空氣入口和出口路徑。通過將吸入路徑限制在鼻道和將呼氣路徑限制在口部, 將吸入迴圈與呼氣迴圈分開。使用者通過口部或鼻吸入汽化物質。嘴件和鼻件是可互換的。汽化器系統可通過不同的延伸部分將汽化物質經由鼻或口部輸送到使用者。 The mask 230 of the carburetor system has an air inlet and an air outlet in which gas from the chamber flows to a user where the user exhales. For example, the mouthpiece or nosepiece provides an air inlet and outlet path. By limiting the inhalation path to the nasal passages and limiting the expiratory path to the mouth, Separate the inspiratory loop from the expiratory loop. The user inhales vaporized material through the mouth or nose. The mouthpiece and nose piece are interchangeable. The vaporizer system can deliver vaporized material to the user via the nose or mouth through different extensions.

當汽化器系統運行時,汽化裝置220連接到罐210,並進一步連接到面罩230,如250所示。 When the vaporizer system is in operation, the vaporizer 220 is coupled to the canister 210 and further coupled to the mask 230, as shown at 250.

圖3示出了汽化器系統300的局部剖視圖。汽化器系統300包括面罩或嘴件或鼻件330、罐或容器310,以及汽化裝置320。汽化裝置320還包括金屬表面322、加熱元件324和溫度計326,其沿金屬表面322設置。 FIG. 3 shows a partial cross-sectional view of vaporizer system 300. The carburetor system 300 includes a mask or mouthpiece or nose piece 330, a can or container 310, and a vaporizer 320. The vaporizer 320 also includes a metal surface 322, a heating element 324, and a thermometer 326 disposed along the metal surface 322.

作為示例,罐310接觸汽化裝置320的金屬表面322以吸收熱量。所述罐是一次性的,並且用液體物質預填充,所述液體物質用基於環糊精的載體配製以用於汽化。所述載體是承載油基和水基物質的兩親性載體。物質和物質的載體被配製成能夠在低於100℃的溫度下有效地汽化以減少有害物質的產生。 As an example, the can 310 contacts the metal surface 322 of the vaporizer 320 to absorb heat. The canister is disposable and pre-filled with a liquid material formulated with a cyclodextrin-based carrier for vaporization. The carrier is an amphiphilic carrier that carries an oil-based and water-based substance. The carrier of the substance and substance is formulated to be effective to vaporize at temperatures below 100 ° C to reduce the production of harmful substances.

加熱元件324沿金屬表面322設置以加熱金屬表面322。金屬表面進一步加熱接觸金屬表面的罐。罐中的液體物質被加熱至目標溫度以汽化成氣體。氣體流入面罩330以供使用者吸入。 Heating element 324 is disposed along metal surface 322 to heat metal surface 322. The metal surface further heats the can that contacts the metal surface. The liquid material in the tank is heated to a target temperature to vaporize into a gas. Gas flows into the mask 330 for inhalation by the user.

例如,在一個實施例中,汽化裝置320的溫度計326檢測金屬表面322的溫度。汽化裝置基於溫度計所檢測的金屬表面的溫度來調節加熱元件的功率。例如,當溫度高於目標溫度時,降低加熱元件的功率,使溫度降低至目標溫度。 For example, in one embodiment, the thermometer 326 of the vaporizer 320 detects the temperature of the metal surface 322. The vaporization device adjusts the power of the heating element based on the temperature of the metal surface detected by the thermometer. For example, when the temperature is higher than the target temperature, the power of the heating element is lowered to lower the temperature to the target temperature.

例如,在一個實施例中,汽化裝置還包括壓力感 測器(現在在圖3中示出),其檢測氣體的氣體壓。壓力感測器設置在氣體的通道。當罐的液體物質耗盡時,氣體壓下降。為了安全目的,當所檢測的氣體壓在預定的壓力範圍之外時,汽化裝置自動關閉。 For example, in one embodiment, the vaporization device also includes a sense of pressure A detector (now shown in Figure 3) detects the gas pressure of the gas. The pressure sensor is placed in the passage of the gas. When the liquid material of the tank is exhausted, the gas pressure drops. For safety purposes, the vaporizer automatically shuts off when the detected gas pressure is outside of the predetermined pressure range.

例如,在一個實施例中,汽化裝置還包括感測器(現在在圖3中示出),其感測使用者的呼吸頻率,從而使汽化物質的輸送與使用者的呼氣頻率同步。閥與感測器通信以控制在使用者吸氣時輸送給使用者的氣體的流量。所述閥由汽化裝置的控制器以與使用者的呼吸頻率同步的頻率開啟和關閉。作為一個示例,汽化裝置的閥和加熱元件由控制器同時開啟和關閉。 For example, in one embodiment, the vaporization device further includes a sensor (now shown in FIG. 3) that senses the user's respiratory rate to synchronize the delivery of vaporized material with the user's expiratory frequency. The valve communicates with the sensor to control the flow of gas delivered to the user as the user inhales. The valve is opened and closed by a controller of the vaporization device at a frequency synchronized with the user's respiratory rate. As an example, the valve and heating element of the vaporizer are simultaneously turned on and off by the controller.

為了增強藥物的輸送效率和吸收,將電荷添加到目標物質或汽化物質的流動通道中。作為一個示例,電離單元設置在物質的氣體的通道,並以正或負電荷離子化氣體以增強用戶對物質的吸收。作為另一示例,使儲存在罐或容器中的物質帶電,以增強使用者對物質的吸收。 In order to enhance the delivery efficiency and absorption of the drug, a charge is added to the flow channel of the target substance or vaporized substance. As an example, the ionization unit is disposed in the passage of the gas of the substance and ionizes the gas with a positive or negative charge to enhance the absorption of the substance by the user. As another example, the substance stored in the can or container is charged to enhance the absorption of the substance by the user.

為了進一步增強汽化物質的輸送效率,液體物質和物質的載體被配製成汽化為4至10μm的粒徑。4至10μm的粒徑為可吸入尺寸,但大於可呼出尺寸,提高了將物質輸送到使用者的效率。 In order to further enhance the transport efficiency of the vaporized substance, the carrier of the liquid substance and substance is formulated to have a particle size of vaporized to 4 to 10 μm. A particle size of 4 to 10 μm is respirable, but larger than the exhalable size, improving the efficiency of delivering the substance to the user.

汽化器系統的面罩330具有輸入腔室334和輸出腔室336。輸入腔室和輸出腔室由分隔件332分隔。諸如氧氣的載氣沿圖3所示箭頭的方向進入輸入腔室,並與汽化物質混合形成混合氣體。混合氣體流入輸出腔室336,並進一步進入使用者的鼻或口部以供吸入。 The mask 330 of the carburetor system has an input chamber 334 and an output chamber 336. The input and output chambers are separated by a divider 332. A carrier gas such as oxygen enters the input chamber in the direction of the arrow shown in Figure 3 and is mixed with the vaporized material to form a mixed gas. The mixed gas flows into the output chamber 336 and further into the nose or mouth of the user for inhalation.

作為示例,嘴件或鼻件提供空氣入口和出口路徑。通過將吸入路徑限制在鼻道和將呼氣路徑限制在口部,將吸入迴圈與呼氣迴圈分開。使用者通過口部或鼻吸入汽化物質。 As an example, the mouthpiece or nosepiece provides an air inlet and outlet path. The suction loop is separated from the expiratory loop by confining the inhalation path to the nasal passage and restricting the expiratory path to the mouth. The user inhales vaporized material through the mouth or nose.

例如,在一個實施例中,汽化器系統還包括流量計以計算由使用者吸入的氣體的體積。汽化器系統基於由使用者吸入的氣體的體積來計算由使用者吸入的物質的消耗劑量,並將由使用者吸入的物質的消耗劑量記錄在汽化器系統的記憶體中或遠端伺服器。 For example, in one embodiment, the vaporizer system also includes a flow meter to calculate the volume of gas inhaled by the user. The carburetor system calculates the consumed dose of the substance inhaled by the user based on the volume of gas inhaled by the user, and records the consumed dose of the substance inhaled by the user in the memory of the vaporizer system or the remote server.

圖4示出了根據示例性實施例向使用者提供汽化物質的方法。 FIG. 4 illustrates a method of providing a vaporized material to a user in accordance with an exemplary embodiment.

方框410表明由汽化器系統的腔室容納一個或多個填充有物質的膠囊。 Block 410 indicates that one or more capsules filled with material are contained by the chamber of the vaporizer system.

考慮一個示例,其中汽化器系統包括具有腔室的汽化裝置、一個或多個填充有物質並放置在腔室內的容器或膠囊,以及可拆卸地連接到汽化器系統的汽化裝置的腔室的面罩。汽化器系統識別膠囊的內容物,並進行相應的加熱方案。 Consider an example wherein the vaporizer system includes a vaporization device having a chamber, one or more containers or capsules filled with material and placed within the chamber, and a mask removably coupled to the chamber of the vaporization device of the vaporizer system. The vaporizer system identifies the contents of the capsule and performs a corresponding heating scheme.

用金屬或箔蓋將物質密封在膠囊或容器內。當膠囊放置在腔室中時,在箔蓋上刺洞以允許汽化物質被吸入。 The substance is sealed in a capsule or container with a metal or foil cover. When the capsule is placed in the chamber, a hole is made in the foil cover to allow the vaporized material to be inhaled.

膠囊被放置在汽化裝置的腔室內,使得膠囊中的物質被加熱並汽化成氣體。密封在膠囊中的物質處於液態,並用基於環糊精的載體配製以用於汽化。膠囊中預填充的物質包括但不限於:中藥調和物、中藥提取物、草藥精華,以及芳香療法精油。所述載體是承載油基和水基物質的兩親性載體。物質和物質的載體被配製成能夠在低於100℃的溫度下有效地汽 化以減少有害物質的產生。 The capsule is placed in the chamber of the vaporization device such that the contents of the capsule are heated and vaporized into a gas. The substance sealed in the capsule is in a liquid state and is formulated with a cyclodextrin-based carrier for vaporization. Pre-filled substances in capsules include, but are not limited to, traditional Chinese medicine blends, Chinese herbal extracts, herbal extracts, and aromatherapy essential oils. The carrier is an amphiphilic carrier that carries an oil-based and water-based substance. The carrier of matter and substance is formulated to be effective in steam at temperatures below 100 ° C To reduce the production of harmful substances.

方框420表明通過用加熱元件將腔室加熱至目標溫度以將物質汽化為粒徑為4至10μm的氣體,用汽化裝置汽化膠囊中的物質。 Block 420 illustrates vaporizing the contents of the capsule with a vaporizer by heating the chamber to a target temperature with a heating element to vaporize the material into a gas having a particle size of 4 to 10 [mu]m.

作為示例,汽化器系統包括控制器,其確定儲存在膠囊中的物質和物質的載體的汽化溫度,並命令加熱元件將膠囊加熱至將物質汽化成氣體以供使用者吸入的汽化溫度。 By way of example, the carburetor system includes a controller that determines the vaporization temperature of the carrier of the substance and substance stored in the capsule and commands the heating element to heat the capsule to a vaporization temperature that vaporizes the substance into a gas for inhalation by the user.

在一個示例性實施例中,汽化裝置包括讀取器和記憶體。讀取器讀取標記在膠囊上的唯一標記號。記憶體儲存唯一標記號和每個唯一標記號的目標溫度,使得控制器從記憶體確定相應於膠囊的唯一標記號的目標溫度,並命令加熱元件將膠囊加熱至被選擇為將物質汽化成氣體以供使用者吸入的溫度。 In an exemplary embodiment, the vaporization device includes a reader and a memory. The reader reads the unique tag number marked on the capsule. The memory stores a unique tag number and a target temperature for each unique tag number such that the controller determines a target temperature corresponding to the unique tag number of the capsule from the memory and commands the heating element to heat the capsule to be selected to vaporize the substance into a gas The temperature at which the user inhales.

汽化器系統的加熱元件加熱膠囊以將膠囊中的液體物質汽化成氣體。在一個示例性實施例中,芯元件連接加熱元件與腔室中的膠囊,以將熱量從加熱元件轉移到膠囊中的物質。在另一示例性實施例中,金屬表面通過膠囊的表面將熱量直接轉移到膠囊中的物質。在另一示例性實施例中,液體物質從膠囊倒入汽化裝置的腔室中,以被金屬表面直接加熱。 The heating element of the carburetor system heats the capsule to vaporize the liquid material in the capsule into a gas. In an exemplary embodiment, the core element connects the heating element to the capsule in the chamber to transfer heat from the heating element to the substance in the capsule. In another exemplary embodiment, the metal surface transfers heat directly to the substance in the capsule through the surface of the capsule. In another exemplary embodiment, the liquid material is poured from the capsule into the chamber of the vaporization device to be directly heated by the metal surface.

液體物質和物質的載體被配製成汽化為4至10μm的粒徑。4至10μm的粒徑為可吸入尺寸,但大於可呼出尺寸,提高了將物質輸送到使用者的效率。 The carrier of the liquid substance and substance is formulated to have a particle size of vaporized to 4 to 10 μm. A particle size of 4 to 10 μm is respirable, but larger than the exhalable size, improving the efficiency of delivering the substance to the user.

為了進一步增強藥物的輸送效率和吸收,將電荷添加到目標物質或汽化物質的流動通道中。作為一個示例,電 離單元設置汽化裝置的腔室中,並以正或負電荷離子化氣體。作為另一示例,在氣流通道中執行電穿孔過程以向氣體添加電荷。作為另一實例,在汽化發生之前,用電荷配製儲存在膠囊中的物質,以增強使用者對物質的吸收。 In order to further enhance the delivery efficiency and absorption of the drug, a charge is added to the flow channel of the target substance or vaporized substance. As an example, electricity The unit is disposed in the chamber of the vaporization device and ionizes the gas with a positive or negative charge. As another example, an electroporation process is performed in the gas flow channel to add a charge to the gas. As another example, a substance stored in a capsule is formulated with a charge prior to vaporization to enhance absorption of the substance by the user.

例如,在一個實施例中,汽化器系統包括溫度計以檢測容納膠囊的腔室的溫度。當所檢測的腔室溫度在預定的溫度範圍之外時,汽化器系統調節加熱元件的功率。例如,當溫度高於目標溫度時,降低加熱元件的功率,使溫度降低至目標溫度。當溫度低於目標溫度時,增加加熱元件的功率,使溫度上升至目標溫度。 For example, in one embodiment, the vaporizer system includes a thermometer to detect the temperature of the chamber containing the capsule. The vaporizer system adjusts the power of the heating element when the detected chamber temperature is outside of a predetermined temperature range. For example, when the temperature is higher than the target temperature, the power of the heating element is lowered to lower the temperature to the target temperature. When the temperature is lower than the target temperature, the power of the heating element is increased to raise the temperature to the target temperature.

例如,在一個實施例中,汽化器系統還包括壓力感測器,其檢測汽化裝置的腔室內的氣體的氣體壓。汽化器系統的控制器接收所檢測的腔室氣體壓,並相應地向系統中適當的元件發送指令。例如,為了安全目的,當所檢測的氣體壓在預定的壓力範圍之外時,關閉汽化裝置。 For example, in one embodiment, the vaporizer system further includes a pressure sensor that detects the gas pressure of the gas within the chamber of the vaporization device. The controller of the carburetor system receives the detected chamber gas pressure and sends instructions to the appropriate components in the system accordingly. For example, for safety purposes, the vaporization device is turned off when the detected gas pressure is outside of a predetermined pressure range.

作為示例,汽化器系統還包括警報器,當腔室的氣體壓或溫度在預定範圍之外時,所述警報器發出信號。汽化裝置在警報器發出信號時自動或手動關閉。 As an example, the carburetor system also includes an alarm that signals when the gas pressure or temperature of the chamber is outside of a predetermined range. The vaporizer is automatically or manually turned off when the alarm signals.

方框430表明通過可拆卸地連接到腔室的面罩的空氣入口,將汽化物質引導至使用者以供吸入。 Block 430 indicates that the vaporized material is directed to the user for inhalation through the air inlet of the mask that is detachably coupled to the chamber.

汽化器系統的面罩具有空氣入口,在所述空氣入口中,來自腔室的氣體流向使用者。例如,鼻件為使用者提供空氣入口路徑。使用者通過鼻吸入汽化物質。 The mask of the carburetor system has an air inlet in which gas from the chamber flows to the user. For example, the nose piece provides the user with an air inlet path. The user inhales vaporized material through the nose.

例如,在一個實施例中,汽化器系統還包括流量 計以計算由使用者吸入的氣體的體積。流量計設置在物質的氣體的通道。汽化器系統基於由使用者吸入的氣體的體積來計算由使用者吸入的物質的消耗劑量,並將由使用者吸入的物質的消耗劑量記錄在汽化器系統的記憶體中或遠端伺服器。 For example, in one embodiment, the vaporizer system also includes flow The volume of gas inhaled by the user is calculated. The flow meter is placed in the passage of the substance's gas. The carburetor system calculates the consumed dose of the substance inhaled by the user based on the volume of gas inhaled by the user, and records the consumed dose of the substance inhaled by the user in the memory of the vaporizer system or the remote server.

方框440表明通過面罩的空氣出口將使用者的呼氣引導至周圍空氣。 Block 440 indicates that the user's exhalation is directed to the surrounding air through the air outlet of the mask.

汽化器系統的面罩具有空氣出口,在所述空氣出口中,使用者呼氣。例如,通過將吸入路徑限制在鼻道和將呼氣路徑限制在口部,將吸入迴圈與呼氣迴圈分開。 The mask of the carburetor system has an air outlet where the user exhales. For example, the suction loop is separated from the expiratory loop by confining the inhalation path to the nasal passage and restricting the expiratory path to the mouth.

例如,在一個實施例中,汽化器系統還包括感測器,其感測使用者的呼吸頻率,從而使汽化物質的輸送與使用者的呼氣頻率同步。感測器設置在面罩的空氣入口。汽化器系統的控制器從感測器接收呼吸頻率,並控制閥的開啟頻率。所述閥由汽化裝置的控制器以與使用者的呼吸頻率同步的頻率開啟和關閉。作為一個示例,汽化裝置的閥和加熱元件由控制器同時開啟和關閉。當閥是開啟的時候,氣體從腔室流向面罩的空氣入口。 For example, in one embodiment, the vaporizer system further includes a sensor that senses the user's respiratory rate to synchronize the delivery of vaporized material with the user's expiratory frequency. The sensor is placed in the air inlet of the mask. The controller of the carburetor system receives the breathing frequency from the sensor and controls the opening frequency of the valve. The valve is opened and closed by a controller of the vaporization device at a frequency synchronized with the user's respiratory rate. As an example, the valve and heating element of the vaporizer are simultaneously turned on and off by the controller. When the valve is open, gas flows from the chamber to the air inlet of the mask.

圖5示出了根據示例性實施例的氣體治療裝置500的方塊圖。氣體治療裝置500包括金屬容器510、主體520,以及嘴件530。主體520包括加熱器522和控制器524。嘴件530包括腔室532、腔室入口534和腔室出口536。 FIG. 5 shows a block diagram of a gas treatment device 500 in accordance with an exemplary embodiment. The gas therapy device 500 includes a metal container 510, a body 520, and a mouthpiece 530. Body 520 includes a heater 522 and a controller 524. The mouthpiece 530 includes a chamber 532, a chamber inlet 534, and a chamber outlet 536.

作為示例,金屬容器510儲存藥液,所述藥液包括一種或多種待被汽化的生物活性物質。藥液還包括具有低於65℃的汽化點溫度的載體。主體520可拆卸地連接到金屬容器。 主體的加熱器522在低於65℃的溫度下加熱金屬容器。儲存在金屬容器中的藥液被加熱和汽化成氣體。 As an example, metal container 510 stores a liquid chemical that includes one or more biologically active substances to be vaporized. The drug solution also includes a carrier having a vaporization point temperature of less than 65 °C. The body 520 is detachably coupled to the metal container. The body heater 522 heats the metal container at a temperature below 65 °C. The liquid stored in the metal container is heated and vaporized into a gas.

控制器524包括溫度控制單元以調節或控制加熱器的溫度。嘴件530的腔室532從金屬容器收集氣體。在使用者吸入時,空氣流過嘴件的腔室入口534,與腔室532中的氣體混合,最後通過腔室出口536流向使用者,從而將生物活性物質傳送給使用者。 Controller 524 includes a temperature control unit to regulate or control the temperature of the heater. The chamber 532 of the mouthpiece 530 collects gas from the metal container. As the user inhales, air flows through the chamber inlet 534 of the mouthpiece, mixes with the gas in the chamber 532, and finally flows through the chamber outlet 536 to the user to deliver the biologically active material to the user.

控制器524具有溫度控制單元,其命令加熱器522將金屬容器510加熱至將藥液汽化成氣體以供使用者吸入的溫度。作為示例,加熱器嵌入或包括在氣體治療裝置的主體中,並包括正溫度係數熱敏電阻以保持目標溫度。 The controller 524 has a temperature control unit that commands the heater 522 to heat the metal container 510 to a temperature at which the liquid is vaporized into a gas for inhalation by the user. As an example, the heater is embedded or included in the body of the gas treatment device and includes a positive temperature coefficient thermistor to maintain the target temperature.

在一個示例性實施例中,金屬容器還包括用作載體以結合生物活性物質的兩親性溶劑。生物活性物質可以是親水或疏水的。作為一個示例,兩親性溶劑承載多個生物物質,所述生物物質具有親水或疏水的草藥成分。 In an exemplary embodiment, the metal container further includes an amphiphilic solvent that acts as a carrier to bind the biologically active substance. The biologically active substance can be hydrophilic or hydrophobic. As an example, an amphiphilic solvent carries a plurality of biological materials having a hydrophilic or hydrophobic herbal component.

溶劑或載體是承載油基和水基物質的兩親性載體。物質和物質的載體被配製為在低於65℃的溫度下有效地汽化以減少有害物質的產生。由於載體的汽化點溫度低,所以需要最小的熱能來產生足夠的表面氣體壓以進行汽化。汽化過程無需傳統超聲波汽化器通常需要的額外機械力或動力。 The solvent or carrier is an amphiphilic carrier that carries an oil-based and water-based material. The carrier of the substance and substance is formulated to be effectively vaporized at a temperature below 65 ° C to reduce the production of harmful substances. Since the vaporization point temperature of the carrier is low, minimal thermal energy is required to generate sufficient surface gas pressure for vaporization. The vaporization process does not require the additional mechanical force or power normally required by conventional ultrasonic vaporizers.

作為示例,藥液被汽化為4至10μm的分子級粒徑的氣體。4至10μm的粒徑是可吸入的,但大於可呼出尺寸,提高了將物質輸送到使用者的效率。相反,傳統超音波噴霧器輸送水滴,而且待輸送給使用者的物質會懸浮在霧中。由於液滴、 重量和疏水性質,大量的物質沿著輸送路徑沉降,無法以傳統噴霧器和藥物輸送裝置到達目的地。 As an example, the drug solution is vaporized into a gas having a molecular size of 4 to 10 μm. A particle size of 4 to 10 μm is respirable, but larger than the exhalable size, improving the efficiency of delivering the substance to the user. In contrast, conventional ultrasonic sprayers deliver water droplets, and the material to be delivered to the user is suspended in the mist. Due to droplets, Weight and hydrophobic properties, a large amount of material settles along the transport path and cannot reach its destination with conventional nebulizers and drug delivery devices.

圖6示出了根據示例性實施例的隨著時間的吸入壓力的曲線圖600。X軸顯示時間,Y軸顯示吸入壓力。 FIG. 6 shows a graph 600 of suction pressure over time, in accordance with an exemplary embodiment. The X axis shows time and the Y axis shows suction pressure.

考慮一個示例,其中氣體治療裝置通過嘴件將汽化物質輸送給使用者。氣體治療裝置包括金屬容器、主體和嘴件。金屬容器儲存藥液,所述藥液包括一種或多種待被汽化的生物活性物質。主體包括加熱金屬容器的加熱器和控制加熱器溫度的控制器。儲存在金屬容器中的藥液被加熱器加熱並汽化成氣體。 Consider an example where a gas therapy device delivers vaporized material to a user through a mouthpiece. The gas treatment device includes a metal container, a body, and a mouthpiece. The metal container stores a drug solution comprising one or more biologically active substances to be vaporized. The body includes a heater that heats the metal container and a controller that controls the temperature of the heater. The liquid medicine stored in the metal container is heated by the heater and vaporized into a gas.

嘴件包括腔室、腔室入口534和腔室出口536。嘴件的腔室從金屬容器收集氣體。嘴件的腔室出口中的氣體流向使用者,從而將生物活性物質輸送給使用者。 The mouthpiece includes a chamber, a chamber inlet 534, and a chamber outlet 536. The chamber of the mouthpiece collects gas from the metal container. The gas in the chamber outlet of the mouthpiece flows to the user to deliver the bioactive material to the user.

在一個示例性實施例中,嘴件的腔室包括或構造有平衡容積。平衡容積在低於65℃溫度下將具有飽和生物活性物質的藥液保持在氣體狀態。腔室的平衡容積由下式確定: In an exemplary embodiment, the chamber of the mouthpiece includes or is constructed with a balancing volume. The equilibrium volume maintains the liquid chemical having a saturated bioactive substance in a gaseous state at a temperature lower than 65 °C. The equilibrium volume of the chamber is determined by:

其中V平衡是腔室的平衡容積,t間隔是使用者的吸氣間隔,T(t)是使用者的吸氣間隔期間的溫度變化,以及P(t)是吸氣間隔期間嘴件的腔室中的氣體壓變化。 Where V balance is the equilibrium volume of the chamber, t interval is the user's inhalation interval, T(t) is the temperature change during the user's inhalation interval, and P(t) is the cavity of the mouthpiece during the inspiratory interval. The gas pressure in the chamber changes.

在一個示例性實施例中,嘴件的腔室入口包括壓力感測器,其檢測使用者的吸入壓力和使用者的吸入持續時間。將所檢測的持續時間和壓力進一步推導為使用者的吸入體積,由下式表示: In an exemplary embodiment, the chamber inlet of the mouthpiece includes a pressure sensor that detects the user's suction pressure and the user's inhalation duration. The detected duration and pressure are further derived as the user's inhalation volume, expressed by:

其中V吸入是使用者吸入體積,P(t)是吸入期間的吸入壓力變化,如圖6的曲線600所示,以及t吸入是使用者的吸入持續時間。 Where V inhalation is the user inhaled volume, P(t) is the inhalation pressure change during inhalation, as shown by curve 600 in Figure 6, and t inhalation is the user's inhalation duration.

氣體治療裝置的控制器基於使用者的吸入容量和嘴件的腔室的容積來調節加熱器的溫度,以達到使用者的目標攝取劑量。例如,V平衡/V吸入的比率可以相關聯以達到使用者攝取劑量的目標濃度。如果該比率超過指定目標,將差值發送到氣體治療裝置的控制器,以調節加熱器的溫度,並視乎每個使用者的吸入容量,為每次吸入注入正確比例的周轉劑量(turn-over dosage)。 The controller of the gas therapy device adjusts the temperature of the heater based on the user's inhalation capacity and the volume of the chamber of the mouthpiece to achieve the target ingestion dose of the user. For example, the ratio of V balance /V inhalation can be correlated to achieve a target concentration of the user's ingested dose. If the ratio exceeds the specified target, the difference is sent to the controller of the gas therapy device to adjust the temperature of the heater and, depending on the inhalation capacity of each user, to inject the correct proportion of the turnover dose for each inhalation (turn- Over dosage).

如本文所用,“汽化”是一種為吸入目的而汽化材料的活性成分或物質的過程。 As used herein, "vaporization" is the process of vaporizing the active ingredient or substance of a material for inhalation purposes.

如本文所用,“容器”或“罐”是用於儲存固體、液體或氣體材料的容器。 As used herein, a "container" or "can" is a container for storing solid, liquid or gaseous materials.

根據示例性實施例的方法和設備作為示例提供,一個方法或設備的示例不應被解釋為限制另一方法或設備的示例。此外,在不同附圖中討論的方法和設備可被添加到其他附圖中的方法和設備或與其交換。此外,特定的數值資料值(例如特定數量、數目或類別等)或其他特定資訊應被解釋為對討論示例性實施例的說明。 The method and apparatus according to the exemplary embodiments are provided as examples, and an example of one method or apparatus should not be construed as limiting an example of another method or apparatus. Moreover, the methods and apparatus discussed in the different figures may be added to or interchanged with the methods and apparatus in the other figures. In addition, specific numerical data values (e.g., specific quantities, numbers, or categories, etc.) or other specific information should be construed as a description of the exemplary embodiments discussed.

Claims (34)

一種汽化物質的設備,所述設備包括:容器,其包括唯一標記號,並儲存待汽化的物質和物質的載體;以及汽化裝置,其可拆卸地連接到所述容器,並且包括:記憶體,其儲存唯一標記號和每個唯一標記號的溫度;讀取器,其讀取所述容器的唯一標記號;控制器,其包括溫度控制單元,所述溫度控制單元從記憶體中選擇分配給唯一標記號的溫度之一;以及加熱元件,其將物質和載體加熱至溫度之一以將物質汽化成氣體以供使用者吸入。 An apparatus for vaporizing a substance, the apparatus comprising: a container including a unique mark number and a carrier for storing a substance and a substance to be vaporized; and a vaporization device detachably coupled to the container, and including: a memory, a temperature at which a unique tag number and each unique tag number are stored; a reader that reads a unique tag number of the container; a controller that includes a temperature control unit that is selectively assigned from the memory One of the temperatures of the unique marker number; and a heating element that heats the substance and carrier to one of the temperatures to vaporize the material into a gas for inhalation by the user. 如申請專利範圍第1項所述之汽化物質的設備,還包括:溫度計,其檢測容器的溫度,並將所檢測的溫度發送到溫度控制單元,其中溫度控制單元基於溫度計所檢測的容器的溫度來調節加熱元件的功率。 The apparatus for vaporizing a substance according to claim 1, further comprising: a thermometer that detects the temperature of the container and sends the detected temperature to the temperature control unit, wherein the temperature control unit is based on the temperature of the container detected by the thermometer To adjust the power of the heating element. 如申請專利範圍第1項所述之汽化物質的設備,還包括:壓力感測器,其檢測容器內的氣體的氣體壓,並將所檢測的氣體壓發送到設備的控制器,其中當所檢測的氣體壓在預定的壓力範圍之外時,控制器關閉設備。 The apparatus for vaporizing a substance according to claim 1, further comprising: a pressure sensor that detects a gas pressure of the gas in the container and transmits the detected gas pressure to a controller of the device, wherein When the detected gas pressure is outside the predetermined pressure range, the controller turns off the device. 如申請專利範圍第1項所述之汽化物質的設備,其中汽化裝置在小於100℃的溫度下將物質汽化為4μm至10μm的尺寸。 The apparatus for vaporizing a substance according to claim 1, wherein the vaporization apparatus vaporizes the substance to a size of 4 μm to 10 μm at a temperature of less than 100 °C. 如申請專利範圍第1項所述之汽化物質的設備,還包括:感測器,其感測使用者的呼吸頻率,並將呼吸頻率發送到 設備的控制器;以及閥,其控制使用者吸入的氣體的流量,其中,所述閥由控制器以與使用者的呼吸頻率同步的頻率開啟和關閉。 The apparatus for vaporizing a substance according to claim 1, further comprising: a sensor that senses a respiratory rate of the user and transmits the respiratory frequency to a controller of the device; and a valve that controls the flow of gas inhaled by the user, wherein the valve is turned on and off by the controller at a frequency synchronized with the respiratory rate of the user. 如申請專利範圍第1項所述之汽化物質的設備,還包括:閥,其控制使用者吸入的氣體的輸出,其中所述閥和加熱元件由設備的控制器以預定頻率同時開啟和關閉。 The apparatus for vaporizing a substance according to claim 1, further comprising: a valve that controls an output of the gas sucked by the user, wherein the valve and the heating element are simultaneously turned on and off by the controller of the apparatus at a predetermined frequency. 如申請專利範圍第1項所述之汽化物質的設備,還包括:電離單元,其設置在物質氣體的通道,並以正或負電荷離子化氣體以增強使用者對物質的吸收。 The apparatus for vaporizing a substance according to claim 1, further comprising: an ionization unit disposed in the passage of the substance gas and ionizing the gas with a positive or negative charge to enhance absorption of the substance by the user. 如申請專利範圍第1項所述之汽化物質的設備,還包括:記錄器,其基於來自流量計的讀數來記錄由使用者吸入的物質的消耗劑量,所述流量計設置在物質氣體的通道。 The apparatus for vaporizing a substance according to claim 1, further comprising: a recorder for recording a consumed dose of the substance inhaled by the user based on a reading from the flow meter, the flow meter being disposed in the passage of the substance gas . 一種汽化器系統,包括:罐,其具有腔室以容納一個或多個填充有液體物質的膠囊,所述液體物質用基於環糊精的載體配製以用於汽化;汽化裝置,其可拆卸地連接到所述罐,並包括:加熱元件,其將液體物質加熱至目標溫度以將液體物質汽化為粒徑為4μm至10μm的氣體;以及控制器,其確定液體物質的目標溫度並開啟和關閉加熱元件;以及面罩,其可拆卸地連接到所述罐的腔室,並且具有空氣入口和空氣出口,在所述空氣入口中,來自腔室的氣體流向 使用者,在所述空氣出口中,使用者呼氣。 A carburetor system comprising: a tank having a chamber for containing one or more capsules filled with a liquid substance, the liquid substance being formulated with a cyclodextrin-based carrier for vaporization; a vaporization device detachably coupled To the canister, and comprising: a heating element that heats the liquid substance to a target temperature to vaporize the liquid substance into a gas having a particle diameter of 4 μm to 10 μm; and a controller that determines a target temperature of the liquid substance and turns the heating on and off An element; and a mask detachably coupled to the chamber of the can and having an air inlet and an air outlet in which gas flow from the chamber The user exhales in the air outlet. 如申請專利範圍第9項所述之汽化器系統,其中每個膠囊都分配有唯一標記號,並且其中汽化裝置還包括:讀取器,其從被放置在所述罐的腔室中的膠囊讀取唯一標記號;以及記憶體,其儲存唯一標記號和每個唯一標記號的目標溫度,使得控制器從記憶體確定相應於膠囊的唯一標記號的目標溫度。 The carburetor system of claim 9, wherein each capsule is assigned a unique marking number, and wherein the vaporizing apparatus further comprises: a reader that reads from the capsule placed in the chamber of the canister A unique tag number is taken; and a memory that stores the unique tag number and the target temperature of each unique tag number such that the controller determines a target temperature corresponding to the unique tag number of the capsule from the memory. 如申請專利範圍第9項所述之汽化器系統,還包括:溫度計,其檢測所述罐的腔室的溫度,並將所檢測的溫度發送到汽化器系統的控制器,其中控制器基於溫度計所檢測的腔室的溫度來調節加熱元件的功率。 The carburetor system of claim 9, further comprising: a thermometer that detects a temperature of the chamber of the tank and sends the detected temperature to a controller of the carburetor system, wherein the controller detects based on the thermometer The temperature of the chamber regulates the power of the heating element. 如申請專利範圍第9項所述之汽化器系統,還包括:壓力感測器,其檢測腔室內的氣體的氣體壓,並將所檢測的氣體壓發送到汽化裝置的控制器,其中當所檢測氣體壓在預定的壓力範圍之外時,控制器關閉汽化裝置。 The carburetor system of claim 9, further comprising: a pressure sensor that detects a gas pressure of the gas in the chamber and transmits the detected gas pressure to a controller of the vaporization device, wherein when detected The controller turns off the vaporization device when the gas pressure is outside of the predetermined pressure range. 如申請專利範圍第9項所述之汽化器系統,還包括:設置在面罩的空氣入口的感測器,其感測使用者的呼吸頻率,並將呼吸頻率發送到汽化裝置的控制器;以及閥,其控制氣體的輸出流量,其中,所述閥由控制器以與使用者的呼吸頻率同步的頻率開啟和關閉。 The carburetor system of claim 9, further comprising: a sensor disposed at an air inlet of the mask, sensing a respiratory rate of the user, and transmitting the respiratory frequency to a controller of the vaporization device; and a valve And controlling the output flow of the gas, wherein the valve is opened and closed by the controller at a frequency synchronized with the respiratory rate of the user. 如申請專利範圍第9項所述之汽化器系統,還包括:閥,其控制使用者吸入的氣體的輸出, 其中所述閥和加熱元件由汽化裝置的控制器以預定頻率同時開啟和關閉。 The carburetor system of claim 9, further comprising: a valve that controls an output of a gas sucked by the user, Wherein the valve and heating element are simultaneously turned on and off by a controller of the vaporization device at a predetermined frequency. 如申請專利範圍第9項所述之汽化器系統,其中使膠囊中的液體物質帶電以增強使用者對液體物質的吸收。 The carburetor system of claim 9, wherein the liquid material in the capsule is charged to enhance absorption of the liquid material by the user. 如申請專利範圍第9項所述之汽化器系統,還包括:芯元件,其將加熱元件與所述罐的腔室中的膠囊連接。 The carburetor system of claim 9, further comprising: a core member that connects the heating element to a capsule in a chamber of the can. 一種由汽化器系統執行的方法,所述汽化器系統提供汽化物質以供使用者吸入,所述方法包括:由汽化器系統的腔室容納一個或多個填充有物質的膠囊,其中所述物質用載體配製,使得所述物質可以在低於100℃的溫度下汽化;由可拆卸地連接到汽化器系統的腔室的汽化裝置汽化膠囊中的物質,其中通過:由汽化器系統的控制器確定汽化具有載體物質的目標溫度;以及用加熱元件將腔室加熱至目標溫度以將物質汽化為粒徑為4μm至10μm的氣體;由可拆卸地連接到腔室的面罩的空氣入口將汽化物質引導至使用者以供吸入;以及由面罩的空氣出口將使用者的呼氣引導至周圍空氣。 A method performed by a carburetor system that provides vaporized material for inhalation by a user, the method comprising: accommodating one or more capsules filled with a substance by a chamber of a carburetor system, wherein the substance is formulated with a carrier The substance may be vaporized at a temperature below 100 ° C; the substance in the capsule is vaporized by a vaporizer detachably connected to the chamber of the carburetor system, wherein: the vaporization has a carrier material as determined by a controller of the carburetor system a target temperature; and heating the chamber to a target temperature with a heating element to vaporize the material into a gas having a particle size of 4 μm to 10 μm; directing the vaporized material to the user by an air inlet of the mask detachably coupled to the chamber For inhalation; and the user's exhalation is directed to the surrounding air by the air outlet of the mask. 如申請專利範圍第17項所述之汽化器系統執行的方法,其中每個膠囊都分配有唯一標記號,並且其中汽化裝置還包括:讀取器,其從被放置在所述罐的腔室中的膠囊讀取唯一標 記號;以及記憶體,其儲存唯一標記號和每個唯一標記號的目標溫度,使得控制器從記憶體確定相應於膠囊的唯一標記號的目標溫度。 The method of the carburetor system of claim 17, wherein each capsule is assigned a unique marking number, and wherein the vaporizing apparatus further comprises: a reader from which is placed in a chamber of the can Capsule reading unique label a symbol; and a memory that stores the unique tag number and the target temperature of each unique tag number such that the controller determines a target temperature corresponding to the unique tag number of the capsule from the memory. 如申請專利範圍第17項所述之汽化器系統執行的方法,還包括:由溫度計檢測腔室的溫度;由汽化器系統的汽化裝置的控制器接收所檢測的腔室溫度;以及當所檢測的腔室溫度在預定的溫度範圍之外時,由汽化器系統的汽化裝置的控制器調節加熱元件的功率。 The method performed by the vaporizer system of claim 17, further comprising: detecting a temperature of the chamber by the thermometer; receiving the detected chamber temperature by a controller of the vaporizer of the vaporizer system; and when detecting the chamber When the chamber temperature is outside of the predetermined temperature range, the power of the heating element is regulated by the controller of the vaporizer of the vaporizer system. 如申請專利範圍第17項所述之汽化器系統執行的方法,還包括:由壓力感測器檢測腔室中的氣體的氣體壓;由汽化器系統的汽化裝置的控制器接收所檢測的腔室氣體壓;以及當所檢測的氣體壓在預定的壓力範圍之外時,關閉汽化裝置。 The method performed by the vaporizer system of claim 17, further comprising: detecting, by the pressure sensor, a gas pressure of the gas in the chamber; receiving, by the controller of the vaporizer of the vaporizer system, the detected chamber gas Pressing; and when the detected gas pressure is outside of the predetermined pressure range, the vaporization device is turned off. 如申請專利範圍第17項所述之汽化器系統執行的方法,還包括:由設置在面罩的空氣入口的感測器檢測使用者的呼吸頻率;由汽化器系統的汽化裝置的控制器接收使用者的呼吸頻率;以及 由汽化裝置的控制器將閥的開啟頻率與使用者的呼吸頻率同步,其中當閥是開啟的時候,氣體從腔室流向面罩的空氣入口。 The method performed by the vaporizer system of claim 17, further comprising: detecting a respiratory rate of the user by a sensor disposed at an air inlet of the mask; receiving a user's by a controller of the vaporization device of the vaporizer system Respiratory frequency; The valve opening frequency is synchronized with the user's breathing frequency by the controller of the vaporization device, wherein when the valve is open, gas flows from the chamber to the air inlet of the mask. 如申請專利範圍第17項所述之汽化器系統執行的方法,汽化器系統還包括:閥,其控制用戶吸入的氣體的輸出,其中所述閥和加熱元件由汽化裝置的控制器以預定頻率同時開啟和關閉。 The method of the carburetor system of claim 17, wherein the carburetor system further comprises: a valve that controls an output of gas drawn by the user, wherein the valve and the heating element are simultaneously turned on by the controller of the vaporization device at a predetermined frequency And off. 如申請專利範圍第17項所述之汽化器系統執行的方法,其中使膠囊中的物質帶電以增強使用者對物質的吸收。 The method of the vaporizer system of claim 17, wherein the substance in the capsule is charged to enhance absorption of the substance by the user. 如申請專利範圍第17項所述之汽化器系統執行的方法,其中汽化器系統還包括電離單元,其設置在氣體的通道,並以正或負電荷離子化氣體以增加使用者對物質的吸收。 The method of the vaporizer system of claim 17, wherein the vaporizer system further comprises an ionization unit disposed in the passage of the gas and ionizing the gas with a positive or negative charge to increase absorption of the substance by the user. 如申請專利範圍第17項所述之汽化器系統執行的方法,其中汽化器系統還包括警報器,當腔室的氣體壓或溫度在預定範圍之外時,所述警報器發出信號,所述的方法,還包括:由流量計檢測由使用者吸入的氣體的體積,所述流量計設置在物質的氣體的通道;由汽化器系統基於由使用者吸入的氣體的體積來計算由使用者吸入的物質的消耗劑量;以及在伺服器記錄由使用者吸入的物質的消耗劑量。 The method of the carburetor system of claim 17, wherein the carburetor system further comprises an alarm, the alarm signaling when the gas pressure or temperature of the chamber is outside a predetermined range, the method The method further includes: detecting, by the flow meter, a volume of gas inhaled by the user, the flow meter being disposed in a passage of the gas of the substance; and calculating, by the vaporizer system, the substance inhaled by the user based on the volume of the gas inhaled by the user The dosage is consumed; and the consumed dose of the substance inhaled by the user is recorded at the server. 一種汽化藥液的氣體治療裝置,包括: 金屬容器,其儲存包含生物活性物質的藥液;主體,其可拆卸地連接到金屬容器,並包括:加熱器,其在低於65℃的溫度下加熱金屬容器,使得儲存在金屬容器中的藥液被加熱並汽化成氣體;以及控制器,其包括溫度控制單元以調節加熱器的溫度;以及嘴件,其包括腔室以收集氣體,其中空氣流入腔室入口並與氣體相混合,並且進一步通過腔室出口流向使用者以將生物活性物質輸送給使用者。 A gas treatment device for vaporizing a liquid medicine, comprising: a metal container storing a chemical liquid containing a biologically active substance; a body detachably connected to the metal container, and comprising: a heater that heats the metal container at a temperature lower than 65 ° C so that the metal container is stored in the metal container The chemical liquid is heated and vaporized into a gas; and a controller including a temperature control unit to adjust the temperature of the heater; and a mouthpiece including a chamber to collect the gas, wherein the air flows into the chamber inlet and is mixed with the gas, and Further flow to the user through the chamber outlet to deliver the bioactive material to the user. 如申請專利範圍第26項所述之氣體治療裝置,其中金屬容器還包括用作載體以結合生物活性物質的兩親性溶劑,其中生物活性物質為親水或疏水的。 The gas treatment device of claim 26, wherein the metal container further comprises an amphiphilic solvent for use as a carrier to bind the biologically active substance, wherein the biologically active substance is hydrophilic or hydrophobic. 如申請專利範圍第26項所述之氣體治療裝置,其中藥液還包括具有低於65℃的汽化點溫度的載體。 The gas treatment device of claim 26, wherein the drug solution further comprises a carrier having a vaporization point temperature of less than 65 °C. 如申請專利範圍第26項所述之氣體治療裝置,其中藥液被汽化為分子級粒徑的氣體。 A gas therapy device according to claim 26, wherein the drug solution is vaporized into a gas having a molecular size particle size. 如申請專利範圍第26項所述之氣體治療裝置,其中金屬容器還包括作為載體的溶劑,所述載體承載氣體狀態的疏水和親水物質。 The gas treatment device of claim 26, wherein the metal container further comprises a solvent as a carrier, the carrier carrying a hydrophobic and hydrophilic substance in a gaseous state. 如申請專利範圍第26項所述之氣體治療裝置,其中金屬容器還包括作為載體的溶劑,所述載體承載多個生物物質,所述生物物質具有親水或疏水的草藥成分。 The gas treatment device of claim 26, wherein the metal container further comprises a solvent as a carrier, the carrier carrying a plurality of biological substances having a hydrophilic or hydrophobic herbal component. 如申請專利範圍第26項所述之氣體治療裝置,其中嘴件的腔室容積為平衡容積,此平衡容積將具有飽和生物活性物質的藥液保持在氣體狀態。 The gas treatment device of claim 26, wherein the chamber volume of the mouthpiece is a balanced volume that maintains the liquid chemical having the saturated bioactive substance in a gaseous state. 如申請專利範圍第26項所述之氣體治療裝置,其中嘴件的腔室入口包括壓力感測器,其檢測使用者的吸入壓力和使用者的吸入持續時間。 The gas treatment device of claim 26, wherein the chamber inlet of the mouthpiece includes a pressure sensor that detects a user's suction pressure and a user's inhalation duration. 如申請專利範圍第26項所述之氣體治療裝置,其中控制器基於使用者的吸入容量和嘴件的腔室的容積來調節加熱器的溫度,以達到使用者的目標攝取劑量。 The gas treatment device of claim 26, wherein the controller adjusts the temperature of the heater based on the suction capacity of the user and the volume of the chamber of the mouthpiece to achieve a target intake dose of the user.
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