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TW201819260A - Enclosing container manufacturing method and manufacturing device - Google Patents

Enclosing container manufacturing method and manufacturing device Download PDF

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Publication number
TW201819260A
TW201819260A TW106135301A TW106135301A TW201819260A TW 201819260 A TW201819260 A TW 201819260A TW 106135301 A TW106135301 A TW 106135301A TW 106135301 A TW106135301 A TW 106135301A TW 201819260 A TW201819260 A TW 201819260A
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TW
Taiwan
Prior art keywords
sheet
cup
sealing cup
lid
sealing
Prior art date
Application number
TW106135301A
Other languages
Chinese (zh)
Inventor
長池剛
Original Assignee
日商第一三共股份有限公司
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Publication of TW201819260A publication Critical patent/TW201819260A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Closing Of Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Packages (AREA)
  • Wrappers (AREA)

Abstract

The objective of the present invention is to provide a suitable method capable of reliably joining a cup and a lid when manufacturing a product in which an opening portion of a cup containing contents is sealed using a lid. To this end, in the method of manufacturing an enclosing container according to the present invention: a lid for covering a cup containing contents is formed from a sheet, which is the material of the lid for sealing an opening portion of the cup, and which is provided in advance with an adhesive layer on a side thereof that is to form an inner surface in intimate contact with an outer surface of a peripheral wall of the cup; and an inner surface of a peripheral wall of the lid is caused to adhere to the outer surface of the peripheral wall of the cup.

Description

封裝容器的製造方法及製造裝置Manufacturing method and manufacturing device of packaging container

[0001] 本發明係有關於,將內容物予以封入的封裝容器的製造方法及製造裝置。[0001] The present invention relates to a method and a device for manufacturing a sealed container in which contents are sealed.

[0002] 經口投予之醫藥的製劑的製造時,作為所使用的方法之一,係有:對有效成分加入賦形劑或結合劑、崩解劑等之添加劑而做均質化而成的粉體,經過壓縮成形後,考慮光所致之品質的劣化或是患者的使用而施以膜衣包覆而加以錠劑化。然而,隨著有效成分的種類,有時候要打錠成具有在市場上流通或處方、投藥時所必須之充分硬度會有困難,除此以外,因為膜衣包覆之際的物理性衝擊而會導致成形體的一部分破損,而會損及錠劑的品質。又,隨著膜衣包覆之際所使用的溶媒,有的時候也會影響到有效成分的穩定性。   [0003] 作為錠劑以外之態樣的製劑,係可舉出膠囊劑。膠囊劑係例如,在預先成形之膠囊中充填有效成分之粉體而予以密封而被製造(參照下記專利文獻1)。但是,膠囊劑,原則上只存在有定型的整齊劃一之形狀及已被規格化之尺寸者,要像錠劑般地獲得具有特徵性的外觀,是困難的。再者,隨著膠囊不同,有的容易開封,甚至可替換膠囊的內容物。   [0004] 另一方面,也有將藉由熱可塑性薄膜所成形之封杯中所充填的粉體,以杵予以壓縮然後進行密封而被製造的態樣(參照下記專利文獻2)。   [0005] 或者也有,在二片明膠薄片之間插入含有有效成分的錠劑後,將二片薄片予以接著然後以模具沖孔成製劑的形狀而被製造的態樣(參照下記專利文獻3)。為了製藥該製劑,係必須要先使用別的裝置而預先製造錠劑。明膠係雖然是在膠囊劑被廣泛採用但由於是動物性蛋白,近年來站在BSE感染的觀點來看,會以烴丙基甲基纖維素作為替代而被使用。 [先前技術文獻] [專利文獻]   [0006]   [專利文獻1] 日本特開平10-192370號公報   [專利文獻2] 日本專利第4417246號公報   [專利文獻3] 日本特開2009-196958號公報[0002] In the manufacture of orally administered pharmaceutical preparations, as one of the methods used, it is made by adding additives such as excipients, binding agents, and disintegrating agents to the active ingredients to homogenize them. After compression molding, the powder is coated with a film coating in consideration of the deterioration in quality due to light or the use of a patient, and is tabletized. However, depending on the type of active ingredient, it may sometimes be difficult to inject tablets to have sufficient hardness necessary for circulation or prescription and administration on the market. In addition, due to physical impact during film coating, Part of the formed body is damaged, and the quality of the tablet is impaired. In addition, depending on the solvent used during film coating, the stability of the active ingredient may be affected in some cases. [0003] Examples of preparations other than lozenges include capsules. Capsules are produced by, for example, filling powder of an active ingredient in a preformed capsule and sealing it (see Patent Document 1 below). However, in principle, capsules only have a uniform shape and a standardized size, and it is difficult to obtain a characteristic appearance like a tablet. Furthermore, with the different capsules, some are easy to open and even replace the contents of the capsules. [0004] On the other hand, there is also a state in which a powder filled in a sealing cup formed by a thermoplastic film is compressed with a pestle and then sealed to be manufactured (see Patent Document 2 below). [0005] Alternatively, there may be a state in which a tablet containing an active ingredient is inserted between two gelatin flakes, and the two flakes are then punched into a preparation shape by a die (see Patent Document 3 below). . In order to manufacture the preparation, it is necessary to use other equipment to make tablets in advance. Although gelatin is widely used in capsules, it is an animal protein. In recent years, from the viewpoint of BSE infection, hydrocarbyl methyl cellulose is used instead. [Prior Art Literature] [Patent Literature] [0006] [Patent Literature 1] Japanese Patent Laid-Open No. 10-192370 [Patent Literature 2] Japanese Patent No. 4417246 [Patent Literature 3] Japanese Patent Laid-Open No. 2009-196958

[發明所欲解決之課題]   [0007] 將有效成分和其他內容物收納至封杯後,將該封杯的開口部以蓋予以密封而製造產品時,為了確實接合這些封杯與蓋,想到將溶解或分散於溶媒的接著劑,在正要接合封杯與蓋之前,塗布至接合面。   [0008] 然而,在採用如此手法的情況下,接著劑中所使用的乙醇或水等之溶媒有可能會損及封杯中所收納之內容物之穩定性或是導致細菌的繁殖等疑慮。   [0009] 本發明係試圖提供一種,將收納有內容物之封杯的開口部以蓋予以密封而製造產品之際,可確實地接合封杯與蓋的合適的方法或製造裝置。 [用以解決課題之手段]   [0010] 本發明所述之封裝容器的製造方法,係從將已收納有內容物之封杯的開口部加以密封所需之蓋的材料,且為在對封杯的周壁的外面做密接的作為內面之一側預先設有接著層的薄片,來形成覆蓋封杯的蓋,同時,將前記蓋的周壁的內面對前記封杯的周壁的外面做接著。   [0011] 若依據本發明,則可將蓋確實接合於收納有內容物之封杯。不僅如此,將蓋接合於封杯之時點上不需要進行接著劑的塗布,可避免接著劑中所被使用的溶媒造成封杯中所收納之內容物的變質或是細菌的繁殖。   [0012] 在將蓋予以成形時,係例如,以前記封杯為公模,在將其開口部朝向前記薄片側之狀態下使薄片對封杯做相對性移動,將薄片抵接於封杯。藉此,可將蓋予以成形,同時,也可進行封杯與蓋的接合。   [0013] 為了使蓋更進一步強固地接著於封杯,在前記蓋的成形後,實施將蓋的周壁的內面對前記封杯的周壁的外面做壓接的工程,較為理想。   [0014] 前記接著層係為例如,使用共聚維酮、甲基丙烯酸共聚物LD、丙烯酸乙酯-甲基丙烯酸甲酯共聚物、聚乙烯吡咯烷酮、或甲基丙烯酸氨基烷基酯共聚物E來構成。   [0015] 前記薄片係為例如以熱可塑性高分子材料為素材的薄膜。此情況下,在前記蓋的成形之前,將共聚維酮、甲基丙烯酸共聚物LD、丙烯酸乙酯-甲基丙烯酸甲酯共聚物、聚乙烯吡咯烷酮、或甲基丙烯酸氨基烷基酯共聚物E溶解於乙醇或水然後塗布至前記薄膜並使其乾燥,藉此就可構成前記接著層。   [0016] 本發明所述之製劑的製造裝置,係具備:蓋成形單元,係從將已收納有內容物之封杯的開口部加以密封所需之蓋的材料,且為在對封杯的周壁的外面做密接的作為內面之一側預先設有接著層的薄片,來形成覆蓋封杯的蓋。   [0017] 前記蓋成形單元,係例如,以前記封杯為公模,在將其開口部朝向前記薄片側之狀態下使薄片對封杯做相對性移動,藉由將薄片抵接於封杯以將前記蓋予以成形。 [發明效果]   [0018] 若依據本發明,則可實現一種,將收納有內容物之封杯的開口部以蓋予以密封而製造產品之際,可確實地接合封杯與蓋的合適的方法或製造裝置。[Problems to be Solved by the Invention] [0007] After storing an active ingredient and other contents in a sealing cup, and sealing the opening of the sealing cup with a lid to manufacture a product, in order to securely join these sealing cups and lids, it is thought that The adhesive dissolved or dispersed in the solvent is applied to the bonding surface just before the sealing cup and the lid are bonded. [0008] However, in the case of such a method, a solvent such as ethanol or water used in the adhesive may impair the stability of the contents contained in the sealing cup or cause doubts such as the reproduction of bacteria. [0009] The present invention seeks to provide a suitable method or a manufacturing device capable of reliably joining a sealing cup and a lid when manufacturing the product by sealing the opening of the sealing cup containing the contents with a lid. [Means to Solve the Problem] [0010] The manufacturing method of the packaging container according to the present invention is a material for a lid required for sealing the opening of the sealing cup in which the contents have been stored, and The outer surface of the peripheral wall of the cup is tightly attached as one side of the inner surface, and a sheet of an adhesive layer is provided in advance to form a cover covering the cup. . [0011] According to the present invention, the lid can be securely joined to the sealing cup containing the contents. Not only that, it is not necessary to apply an adhesive at the time of bonding the lid to the sealing cup, which can prevent the solvent used in the adhesive from causing deterioration of the contents contained in the sealing cup or multiplication of bacteria. [0012] When the lid is formed, for example, the sealing cup is previously described as a male mold, and the sheet is relatively moved to the sealing cup with the opening portion facing the sheet side, and the sheet is abutted against the sealing cup. . Thereby, the lid can be formed, and at the same time, the sealing cup and the lid can be joined. [0013] In order to make the lid adhere to the cup more firmly, it is preferable to carry out a process of crimping the inside of the peripheral wall of the lid to the outside of the peripheral wall of the former seal cup after forming the former cover. [0014] The preamble layer is, for example, copovidone, methacrylic acid copolymer LD, ethyl acrylate-methyl methacrylate copolymer, polyvinylpyrrolidone, or aminoalkyl methacrylate copolymer E. Make up. [0015] The foregoing sheet is, for example, a thin film made of a thermoplastic polymer material. In this case, before forming the cap, copovidone, methacrylic acid copolymer LD, ethyl acrylate-methyl methacrylate copolymer, polyvinylpyrrolidone, or aminoalkyl methacrylate copolymer E is prepared. The pre-adhesive layer can be formed by dissolving in ethanol or water, and then coating and drying the pre-film. [0016] The device for manufacturing a preparation according to the present invention includes a lid forming unit, which is a material for a lid required to seal an opening portion of a sealing cup in which the contents have been stored, and The outer surface of the peripheral wall is tightly attached, and one side of the inner surface is provided with a sheet of an adhesive layer in advance to form a lid covering the sealing cup. [0017] The preform cover forming unit is, for example, a preform seal cup which is a male mold, and moves the sheet relative to the seal cup with the opening portion facing the preform sheet side, and abuts the sheet on the seal cup. The former cap is formed. [Effects of the Invention] [0018] According to the present invention, a suitable method for reliably joining the sealing cup and the lid when the product is manufactured by sealing the opening of the sealing cup containing the contents with a lid can be realized. Or make a device.

[0020] 以下,參照圖式,說明本發明的實施形態。   [0021] <概要>首先,說明本實施形態中的封裝容器1、2及製劑的製造方法的概要。在本實施形態中,將粉體30所壓縮而成的成形品3藉由封裝容器1、2包裝的基劑薄片10、20予以包裹而製造包裝錠。包裝錠係為,在從薄片10所成形的具有容積之封杯1中,插入內容物,例如將粉體30壓縮而得的成形品3後,將該當封杯1的開口部以從薄片20所成形之蓋2予以密封而成的製劑。所謂粉體,係指微小個體的集合體,包括所謂顆粒等之粒體的集合體、和比粒體還小之形狀的粉末的集合體之概念。如圖1及圖2所示,本實施形態的封裝容器1、2及製劑的製造方法,係具備:封杯成形工程,係從薄片10來形成用以收容成形品3所需之封杯1;和粉體壓縮工程,係將粉體30予以壓縮而形成作為包裝錠之內容物的成形品3;和插入工程,係在封杯1中插入成形品3;和封杯加工工程,係從已插入有成形品3之封杯1,切除薄片10的殘部13;和密封工程,係將已插入有成形品3之封杯1的開口部,藉由薄片20而予以密封。   [0022] 在封杯成形工程中,係如圖1(I)所示,令作為封杯1之材料的薄片10對公模507做相對性移動,藉由將薄片10抵接至公模507,以使具有容積之封杯1從該當薄片10突出。藉此形成了具備底壁12、和沿著底壁12之外周緣而立起之周壁11之形狀的封杯1。   [0023] 作為封杯1之材料的薄片10,係為使用熱可塑性高分子材料的薄的薄膜。若製造對象之製劑是經口投予之醫藥的情況,則將可使用於醫藥的素材,例如烴丙基甲基纖維素或聚乙烯醇等為素材的薄膜,作為薄片10而採用。此外,在製造薄的薄膜狀的薄片10時,亦可在該當薄片10的材料中,調配有可塑劑。又,薄片10的材料中係亦可調配有例如氧化鈦,來作為用來抑制包裝錠的內容物被光曝曬所需的遮光劑。   [0024] 然後,如圖1(II)所示,將連在封杯1上的多餘的薄片10的剩餘部位,例如藉由對該當薄片照射雷射光L的雷射加工,而大致切除。在此階段中,從封杯1的開口部,換言之是從周壁11的緣端,往外側方延伸出去的鍔狀的薄片10的殘部13係會存留,封杯1會成為像是帽子般的形狀。薄片10的切斷時所使用的雷射光L的波長,係必須要為可讓薄片10吸收該雷射光L之能量的波長。在薄片10的透明性較高的情況下,則是使用長波較長的雷射,例如波長10.6μm或9.4μm的二氧化碳雷射。   [0025] 在粉體壓縮工程中,係在被設於臼桌602的上下貫通之臼孔601中從下方插入下杵603的尖端部(上端部),在該臼孔601中充填了含有有效成分(若製劑為醫藥時則為主藥)的粉體30後,在臼孔601中從上方插入上杵604的尖端部(下端部),藉由上杵604及下杵603將臼孔601內的粉體30予以壓縮而獲得成形品3(參照圖10乃至圖12)。被壓縮成形的粉體30係為有效成分、和有效成分以外的成分(若錠劑為醫藥時,則為賦形劑、結合劑、崩解劑、潤澤劑、穩定劑、防腐劑等)的混合物。又,於粉體壓縮工程中所製造的成形品3,係並不一定要具有作為可在市場上流通之錠劑所必須之充分的硬度,只要直到被收容至封杯1以前的期間,能夠擔保維持粉體30的份量或形狀之程度的保形性即可。亦即,在粉體壓縮工程中,可以使成形品3作為錠劑而具有充分的硬度而強力地壓縮粉體30,也可以用使成形品3容易缺損或崩解之程度的壓力來壓縮粉體30。   [0026] 在插入工程中,係如圖1(III)所示,以使封杯1的開口部朝向上方的狀態,將透過粉體壓縮工程所得的成形品3,從上方插入封杯1內。   [0027] 封杯加工工程中,係如圖1(IV)所示,將從封杯1的開口部朝外側方延伸出去的鍔狀的殘部13,予以切除。此時,一面使含有封杯1的薄片10繞著軸α而旋轉,一面進行將光軸是朝向對該旋轉軸α之延伸方向做交叉(尤其是正交)之方向的雷射光L,在從薄片10的殘部13突出的封杯1的周壁11的緣端附近之部位,從外側方做照射的雷射加工。藉由如此加工,在封杯1的開口緣不會殘留多餘的薄片10的小片,可從封杯1確實地切除薄片10的殘部13,可完成只具有底壁12及周壁11的封杯1。薄片10的殘部13之切斷中所使用的雷射L,係為例如波長10.6μm或9.4μm的二氧化碳雷射。   [0028] 密封工程係含有:蓋成形工程,係從薄片20來形成用以密封封杯1之開口部所需之蓋2;和蓋加工工程,係從已形成之蓋2切除薄片20的殘部23;和壓接工程,係對蓋2的周壁21施加壓力以將其壓接至封杯1的周壁11。在蓋成形工程中,係如圖2(V)所示,將已插入有成形品3之封杯1當作公模,令作為蓋2之材料的薄片20對封杯1做相對性移動,藉由將薄片20抵接至封杯1,以從該當薄片20而使呈現將封杯1予以包覆之形狀的蓋2突出。藉此形成了具備頂壁22、和沿著頂壁22之外周緣而下垂之周壁21之形狀的蓋2。同時,蓋2的周壁21的內面係密接於封杯1的周壁11的外面,蓋2的頂壁22係將封杯1的開口予以閉塞。   [0029] 作為蓋2之材料的薄片20也是,和作為封杯1之材料的薄片同樣地,係為使用熱可塑性高分子材料的薄的薄膜。若製造對象之製劑是經口投予之醫藥的情況,則將可在服用之人體內溶解的素材,例如烴丙基甲基纖維素或聚乙烯醇等為素材的薄膜,作為薄片20而採用。此外,在製造薄的薄膜狀的薄片20時,亦可在該當薄片20的材料中,調配有可塑劑。又,薄片20的材料中係亦可調配有例如氧化鈦,來作為用來抑制包裝錠的內容物被光曝曬所需的遮光劑。   [0030] 有時候,作為蓋2之材料的薄片20,係在與封杯1的周壁11的外面密接的內面的一側,預先設有接著層24(參照圖19、圖20)。接著層24係為例如,使用共聚維酮、甲基丙烯酸共聚物LD、丙烯酸乙酯-甲基丙烯酸甲酯共聚物、聚乙烯吡咯烷酮、或甲基丙烯酸氨基烷基酯共聚物E來構成。更具體而言,將作為接著劑的共聚維酮等連同可塑劑一起溶解於乙醇或水,將其塗布於薄片20也就是烴丙基甲基纖維素薄膜或聚乙烯醇薄膜等然後使其乾燥,藉此而構成接著層24。在對薄片20塗布接著劑之際,亦可使用由金屬網等所構成的版型,接著劑塗布成無數的點狀。或者,亦可考慮不是將接著劑分散於溶媒而塗布,而是製作將接著劑當作素材的薄的薄膜,藉由將該薄膜對薄片20也就是烴丙基甲基纖維素薄膜等一面施加熱及壓力而一面進行接著,以構成接著層24。接著層24,係並不一定要設在薄片20的全面,只要至少設在薄片20的周壁21(其內面係接著於封杯1的周壁11的外面)及頂壁22(其下面係接著於成形品3的上面)的部位即可。   [0031] 在以蓋成形工程來形成蓋2的過程中,蓋2的周壁21的內面係接合至封杯1的周壁11的外面。在蓋2之材料的薄片20上設有接著層24的情況下,此時藉由對薄片20加熱,該當接著層24就會將蓋2的周壁21的內面與封杯1的周壁11的外面予以接著。   [0032] 然後,如圖2(VI)所示,將連在蓋2上的多餘的薄片20的剩餘部位,例如藉由對該當薄片20照射雷射光L的雷射加工,而大致切除。在此階段中,從蓋2的開口部,換言之是從周壁21的緣端,往外側方延伸出去的鍔狀的薄片20的殘部23係會存留,蓋2會成為像是帽子般的形狀。如前述,薄片20之切斷中所使用的雷射L,係為例如波長10.6μm或9.4μm的二氧化碳雷射。   [0033] 接下來,在蓋加工工程中,係如圖2(VII)所示,將從蓋2的開口部朝外側方延伸出去的鍔狀的殘部23,予以切除。此時,一面使含有蓋2的薄片20繞著封杯1等的共軸α而旋轉,一面進行將光軸是朝向對該旋轉軸α之延伸方向做交叉(尤其是正交)之方向的雷射光L,在從薄片20的殘部23突出的蓋2的周壁21的緣端附近之部位,從外側方做照射的雷射加工。此時,藉由使雷射光L的焦點對合於蓋2的周壁21,及/或調整雷射光L的輸出,就可使封杯1的周壁11不會受到雷射光L所致之切斷以外的其他損傷。藉由如此加工,在蓋2的開口緣不會殘留多餘的薄片20的小片,可從蓋2確實地切除薄片20的殘部23,可完成只具有頂壁22及周壁21的蓋2。封杯1的周壁11及蓋的周壁21會重合而完成包裝錠的周壁,因此已被包裝的成形品3的側面不會露出。如前述,薄片20之切斷中所使用的雷射L,係為例如波長10.6μm或9.4μm的二氧化碳雷射。   [0034] 再者,在壓接工程中,係將蓋2的周壁21從外側方往內側方按壓,將蓋2的周壁21的內面對封杯1的周壁11的外面進行壓接。但是,壓接工程的實施係並非必須。在蓋成形工程中從薄片來形成蓋2時,若蓋2的周壁21的內面對封杯1的周壁11的外面係為充分強固地附著者,則亦可不進行如此的壓接。   [0035] 經由以上的工程,如圖2(VIII)所示的包裝錠,亦即將粉體30壓縮成的成形品3以由封杯1及蓋2所成之包裝膠囊加以包裹的製劑,就被完成。   [0036] 如圖3所示,為了實施本實施形態的製劑的製造方法而使用的製造裝置,係為從薄片來形成封杯1及蓋2的包裝膠囊成形機500,與從粉體30來形成成形品3的粉體壓縮成形機600的組合。以下,詳述本實施形態的製造裝置。   [0037] <封杯成形單元>封杯成形單元A,係在包裝膠囊成形機500內,負責從薄片10來形成具有容積之封杯1的封杯成形工程。如圖4乃至圖9所示,於封杯成形單元A中,首先,於薄片切出位置501上,從作為封杯1之材料的薄片10的料帶502,切出所定寸法的圓形狀的薄片10。薄片10的切出係藉由,例如沿著所被切出的薄片10的輪廓照射雷射光L而進行。然後,將該已切出之薄片10,於成形位置503上以保定機構504加以保持固定。保定機構504,係藉由上下成對的環狀的中空的構件505、506而將薄片10予以上下夾持。保定機構504之下側的構件506,係可在薄片切出位置501與成形位置503之間移動,於薄片切出位置501上收取已切出之薄片10,並搬運至成形位置503為止。   [0038] 在成形位置503上,朝上方突出而呈略圓柱狀的公模507,係在保定機構504的下方待機。然後,從薄片10來看與公模507的相反側,亦即從存在於薄片10的上方,內藏有風扇的風管508,往薄片10吹拂溫風而將熱可塑性的薄片10加溫。然後,將薄片10予以夾持而保持固定的保定機構504,朝公模507而下降,將薄片10抵接於公模507的尖端面(上端面)(圖5)。同時,將從薄片10來看將公模507側減壓至比風管508側還低壓,具體而言是將薄片10之下方的氛圍加以吸引,以使薄片10被吸附於公模507的尖端部(上端部)(圖6)。結果,具有與公模507的尖端部的外形對應之形狀之容積的封杯1,係從薄片10上方突出而被成形。該封杯1係具有,沿著公模507的尖端部的外周面之形狀的呈圓筒狀的周壁11,和沿著公模507的尖端面之形狀的底壁12。   [0039] 使封杯1從薄片10突出而成形後,保定機構504係將該薄片10予以夾持同時從公模507遠離般地而上升。接下來,公模507係往下方大幅退避,封杯翻轉機509係由沿著X軸方向的側方而進入到保定機構504的正下方。封杯翻轉機509,係從可繞著水平軸而旋轉的水平支軸510,沿著其正交方向而使吸附臂511突出,負責使朝向下方的封杯1的開口部變成朝向上方地而將封杯1予以翻轉。吸附臂511的尖端部,係呈現與公模507的尖端部同等之外形。在封杯翻轉機509的內部,係形成有用來吸引氛圍所需的吸引通路512,該吸引通路512係開口於吸附臂511的尖端面。封杯翻轉機509,係以將該吸附臂511朝上的姿勢,而被定位在封杯1的正下方。然後,夾持住薄片10的保定機構504係再度下降,在封杯1內插入吸附臂511的尖端部。此狀態下一旦將吸引通路512予以吸引而使其負壓化,則含有封杯1的薄片10就被吸附在吸附臂511的尖端面。   [0040] 接下來,對封杯1的開口部上所連著的多餘的薄片10的剩餘部位照射雷射光L,切除該當剩餘部位(圖7)。此時,沿著與薄片10的剩餘部位正交的Z軸方向亦即上下方向(圖示例子中係從上方),在從封杯1的開口緣稍微偏向外側方的位置照射雷射光L,同時,使該雷射光L的照射位置,沿著比封杯1的開口緣的直徑還大的圓形狀的輪廓β而描繪弧形般地移動而進行掃描。藉此,沿著雷射光L的照射位置的軌跡而切斷薄片10。在已經切除薄片10之剩餘部位的封杯1的開口部,係會有從封杯1的周壁11折曲而往外側方伸出的鍔狀的薄片10的殘部13存留。從封杯1切除下來的薄片10的剩餘部位,係之後被吸引而去除。   [0041] 薄片的剩餘部位切除後,使吸附著封杯1的吸附臂511及水平支軸510做半旋轉而使吸附臂511朝下以將封杯1予以翻轉,同時,使吸附臂511及水平支軸510沿著X軸方向而往側方位移,將開口部朝上的封杯1搬運至移送機構513的正上方之位置為止。然後,使移送機構513的移送體514朝向吸附臂511而上升。移送體514中係形成有,在其上面做開口的軸孔515。軸孔515的內徑,係從移送體514的上面起至略等於封杯1的周壁11的高度寸法之深度為止(例如從移送體514的上面起至約5mm之深度為止)的部分處,是略等於封杯1的周壁11的外徑,但比此處還要下方的部分則是變成比封杯1的周壁的外徑還窄。一旦移送體514上升,則朝下的吸附臂511的尖端部及其上所吸附的封杯1就被收入在移送體514的軸孔515內(圖8)。如此,藉由停止封杯翻轉機509的吸引通路512的吸引,就可從吸附臂511往移送體514遞交封杯1。此時,從封杯1的開口緣往外側方延伸出去的鍔部13,係卡合於移送體514的上面中的軸孔515的開口的周緣。其後,移送體514係下降而從吸附臂511遠離,封杯翻轉機509係回到原位置(圖9)。又,公模507係朝原位置而上升。在移送體514的軸孔515中收容有封杯1的移送機構513,其後係將該封杯1以巡迴各處之單元B、C、E、F、G、H的方式加以移送而作用。   [0042] <粉體壓縮單元>粉體壓縮單元B,係在粉體壓縮成形機600內,負責將粉體30予以壓縮而獲得應裝填至封杯1的成形品3的粉體壓縮工程。如圖10乃至圖12所示,於粉體壓縮單元B中,首先,在具有上下貫通之臼孔601的臼桌602的臼孔601中,從下方插入下杵603的尖端部(上端部),且調整該下杵603的高度,以在臼孔601內確保充填所要量之粉體30所需之容積。此時,從上方面對臼孔601的上杵604係上升,將臼桌602上的臼孔601的周圍之領域予以開放。然後,以從上方覆蓋臼桌602之臼孔601的方式使充填裝置(給料滑槽)605沿著臼桌602的上面而移動,在臼孔601內充填粉體30(圖11)。完成粉體30之充填的充填裝置605,係從臼桌602上的臼孔601的周圍的領域退避。   [0043] 接著,使上杵604下降而將該尖端部(下端部)從上方插入至臼孔601,以上杵604的尖端部與下杵603的尖端部按壓臼孔601內的粉體30而壓縮之,形成成形品3(圖12)。   [0044] <插入單元>插入單元C,係位於粉體壓縮成形機600內,與粉體壓縮單元B共用相同的構成元件,負責將壓縮粉體30所得的成形品3插入至封杯1的插入工程。如圖10、圖13及圖14所示,於插入單元C中,係在粉體壓縮工程所致之粉體30的壓縮的完成後,使下杵603下降,將其尖端面(上端面)從成形品3的下面拉離。此時,壓縮粉體30所成的成形品3係留在臼孔601內。然後,使上杵604及臼桌602上升,在臼孔601的下方確保沿著Y軸方向而朝側方開放的空間。然後,該空間中,係有在軸孔515中收容封杯1而支持該當封杯1的移送機構513的移送體514,會沿著Y軸方向而由下方進入(圖13)。進入該當空間的移送體514的軸孔515及封杯1的中心軸α,係與臼桌602的臼孔601的中心軸同軸,亦即雙方的中心軸是在上下方向的Z軸方向來看是一致的。   [0045] 接下來,將移送體514稍微往上持起,使上杵604下降,將滯留在臼孔601內的成形品3,從上方戳入封杯1內(圖14)。結果,在封杯1內係有成形品3被插入。然後,使上杵604再度上升,同時,使移送體514稍微下降,使移送體514從臼桌602之下方的空間退避。一旦移送體514退避,則臼桌602就下降至原位置,上杵604的尖端部係從臼孔601拔出。又,下杵603也會上升,其尖端部會再度進入臼孔601內。   [0046] <封杯加工單元>封杯加工單元E,係位於包裝膠囊成形機500內,負責將從已被插入有成形品3之封杯1之開口部往外側方伸出之鍔狀的薄片10的殘部13予以切除的封杯加工工程。如圖15乃至圖17所示,於封杯加工單元E中,首先,將使加工對象的封杯1繞著其中心軸α而旋轉所需的旋轉台522,朝著加工位置523做進出(圖16)。旋轉台522係具備:朝上下方向伸長並可繞著其中心軸亦即鉛直軸而旋轉的軸體524及活塞525、和作為將軸體524予以旋轉驅動之驅動源的馬達526。在軸體524的內部係形成有:沿著上下方向而延伸的負壓通路527、和位於負壓通路527之下方而連通至負壓通路527的負壓產生空間528。負壓通路527,係開口於軸體524的尖端面(上端面)。活塞525,係從下方插入至負壓產生空間528。軸體524與活塞525,係例如做花鍵接合,對於軸體524,活塞525係可相對地沿著上下方向而位移,而另一方面,當軸體524繞著中心軸旋轉時則活塞525與軸體524係會一體而旋轉。負壓產生空間528的容積,係藉由活塞525對於軸體524做相對性上下移動而被擴張、壓縮。又,活塞525係與馬達526的輸出軸直接連結。   [0047] 將已被插入有成形品3的封杯1予以支持的移送機構513的移送體514,係往旋轉台522的上方移動。此時,軸體524的中心軸,與移送體514的軸孔515及封杯1的中心軸α,係為同軸。然後,一旦使移送體514下降,則軸體524的尖端部(上端部)就會收入在移送體514的軸孔515內,其尖端面會抵接或極接近於封杯1的底壁12。在此狀態下,一旦使軸體524上升,則軸體524的尖端部就會比移送體514的上面還往上方突出,將封杯1的底壁12予以頂起般地使封杯1及薄片10的殘部13從移送體514的上面浮起。同時,連結至馬達526的活塞525係對軸體524而相對性地往下方位移,使負壓產生空間528的容積擴大而產生負壓,該負壓係透過負壓通路527而使封杯1的底壁12被吸附於軸體524的尖端面。   [0048] 在封杯加工工程中,為了將封杯1的開口部上所連著的鍔狀的殘部13予以切除,在封杯1的周壁11的緣端(上端)附近的部位,從沿著X軸方向的側方,照射雷射光L。因此,將反射雷射光L而使其光軸轉向X軸方向的反射鏡(或45°直角稜鏡)529,配置在從X軸方向面對於從移送體514的上面浮起之封杯1的周壁11的高度。然後,啟動馬達526而使活塞525、軸體524及吸附於其的封杯1繞著其中心軸α而旋轉,同時,將雷射光L透過反射鏡529而照射至封杯1的周壁11的緣端附近之部位(圖17)。雷射光L的照射,係使照射位置沿著封杯1的周壁11巡迴複數周回(例如二周)而續行。其結果為,可將呈鍔狀之薄片10的殘部13,從封杯1的開口部切除。從封杯1切離的薄片10的殘部13,係之後被吸引而去除。   [0049] 從封杯1切除了薄片10的殘部13後,軸體524係下降,且移送體514係上升。此時,由於活塞525是對軸體524相對性地往上方位移,因此將封杯1的底壁12吸附於軸體524的尖端面的負壓會消失。此外,在移送體514的上面中的軸孔515的開口的周緣做卡合的薄片10的殘部13是已經從封杯1切離,但如之前所說明,於移送體514的軸孔515之下方的部分,其內徑是比封杯1的周壁11的外形還窄。因此,封杯1係不會深陷於軸孔515內,被移送體514所支持同時與移送體514一起上升。軸體524從移送體514的軸孔515往下方脫離後,旋轉台522係從加工位置523退避。   [0050] <密封單元>密封單元,係在包裝膠囊成形機500內,負責將已被插入有成形品3的封杯1的開口部以薄片20加以密封的密封工程。在本實施形態中,密封單元係含有以下所述的蓋成形單元F、蓋加工單元G及壓接單元H。   [0051] 蓋成形單元F,係與封杯成形單元A共用相同的構成元件,負責從薄片20形成將封杯1的開口部予以密封所需的蓋2的蓋成形工程。如圖18乃至圖22所示,於蓋成形單元F中,薄使將片10的殘部13予以切除後的封杯1予以支持的移送機構513的移送體514下降,且使其移動到成形位置503所在的保定機構504之下方的位置為止。另一方面,於薄片切出位置501上,從作為蓋2之材料的薄片20的料帶530切出所定寸法的圓形狀的薄片20,將已切出之薄片20於成形位置503上藉由保定機構504而加以保持固定(圖19)。此時,保定機構504之下側的構件506,係於薄片切出位置501上收取已切出之薄片20,並搬運至成形位置503為止。作為蓋2之材料的薄片20的切出,係與作為封杯1之材料的薄片10的切出藉由同樣的雷射處理而進行。此外,在作為蓋2之材料的薄片20的朝下面,預先設有接著層24。   [0052] 接著,從移送體514的下方,在該當移送體514的軸孔515中插入支持軸531。支持軸531,係從薄片形成蓋2之際會作為公模,擔任將已被插入有成形品3的封杯1由下方加以支持的角色。在支持軸531的內部,係形成有用來吸引氛圍所需的吸引通路532,該吸引通路532係開口於支持軸531的尖端面(上端面)。支持軸531,係使其尖端面上升至與移送體514的上面略相等之高度為止,藉此,將封杯1的底壁12抬起至與移送體514的上面略相等之高度為止,使封杯1從送體514的軸孔515往上方外露。然後,在此狀態下將吸引通路532予以吸引而負壓化,將封杯1的底壁12吸附於支持軸531的尖端面而固定。   [0053] 然後,從薄片20觀看而與封杯1相反側,亦即存在於薄片20之上方,內藏有風扇的風管508,往薄片20吹拂溫風而將熱可塑性的薄片20加溫。其後,將薄片20予以夾持並保持固定的保定機構504,朝向作為公模的封杯1而下降,使薄片20抵接於封杯1的開口緣(上緣)及封杯1中所被插入之成形品3的上面(圖20)。與此同時,從薄片20觀看將封杯1側減壓成比風管508側還低壓,具體而言係將薄片20之下方的氛圍加以吸引,藉此以使薄片20被吸附於封杯1(及移送體514的上面)(圖21)。結果,具有封杯1的周壁11的外面及成形品3的上面的外形所對應之形狀之容積的蓋2,係從薄片20往上方突出而被成形。該蓋2係具有:沿著封杯1的周壁11的外周之形狀的呈圓筒狀的周壁21、和沿著成形品3的上面之形狀的頂壁22。然後,蓋2的成形時,蓋2的周壁21的內面係接合於封杯1的周壁11的外面,且頂壁22的下面係接合於封杯1中所被插入之成形品3的上面。尤其是,作為蓋2的薄片20的朝下面,亦即面對封杯1及成形品3之一側的面上預先設有接著層24的情況下,在蓋2的成形時,該周壁21的內面係會接著於封杯1的周壁11的外面,同時,該當具有接著層24的頂壁22的下面係接著於封杯1中所被插入之成形品3的上面。   [0054] 將蓋2從薄片20突出而成形後,停止支持軸531的吸引通路532的吸引,解除封杯1的底壁12對支持軸531之尖端面的吸附。然後,保定機構504係將形成了蓋2的薄片20予以夾持並上升,移送體514也追隨著保定機構504而上升。此時,封杯1與蓋2係做接合,與該蓋2呈一體的薄片20係被保定機構504所夾持,而且薄片20的剩餘部位係被載置於移送體514的上面,因此封杯1及蓋2也是以從移送體514的上面朝上方外露的狀態而連同保定機構504及移送體514一起上升。   [0055] 接下來,對蓋2的開口部上所連著的多餘的薄片20的剩餘部位照射雷射光L,將該當剩餘部位切除(圖22)。此時,沿著與薄片20的剩餘部位正交的上下方向,在比蓋2的開口緣稍微偏倚外側方的位置照射雷射光L,同時,該雷射光L的照射位置也是沿著直徑比蓋2的開口緣還大的圓形狀的輪廓β而描繪圓弧地移動而進行掃描。藉此,沿著雷射光L的照射位置的軌跡而切斷薄片20。薄片20的剩餘部位切除後的蓋2的開口部係存留有,從蓋2的周壁21折曲而朝外側方伸出的鍔狀的薄片20的殘部23。該薄片20的殘部23,係卡合於移送體514的上面中的軸孔515的開口的周緣,將封杯1及蓋2保持成從移送體514的上面上方突出的狀態。從蓋2切離的薄片20的剩餘部位,係之後被吸引而去除。   [0056] 薄片20的剩餘部位切除後,支持封杯1及蓋2的移送體514係略為下降,同時,支持軸531係往下方大幅退避。   [0057] 蓋加工單元G,係與封杯加工單元E共用相同的構成元件,負責將從密封住封杯1之蓋2的開口部往外側方伸出的鍔狀的薄片20的殘部23予以切除的蓋加工工程。如圖23及圖24所示,於蓋加工單元G中,首先,使支持封杯1及蓋2的移送機構513的移送體514朝向加工位置523而移動(圖23)。該移送體514,係在旋轉台522的上方的位置待機。而且,使旋轉台522往加工位置523進出。在加工位置523上,旋轉台522的軸體524的中心軸,與移送體514的軸孔515、封杯1及蓋2的中心軸α係為同軸。然後,一旦使移送體514下降,則軸體524的尖端部就會收入在移送體514的軸孔515內,其尖端面會抵接或極接近於封杯1的底壁12。在此狀態下,一旦使軸體524上升,則軸體524的尖端部就會比移送體514的上面還往上方突出,將封杯1的底壁12予以頂起般地使封杯1、蓋2及薄片的殘部從移送體514的上面浮起。同時,連結至馬達526的活塞525係對軸體524而相對性地往下方位移,使負壓產生空間528的容積擴大而產生負壓,該負壓係透過負壓通路527而使封杯1的底壁12被吸附於軸體524的尖端面。   [0058] 在蓋加工工程中,為了將蓋2的開口部上所連著的鍔狀的殘部23予以切除,在蓋2的周壁21的緣端(下端)附近的部位,從沿著X軸方向的側方,照射雷射光L。因此,將反射雷射光L而使其光軸轉向X軸方向的反射鏡529,配置在從X軸方向面對於從移送體514的上面浮起之蓋2的周壁21的高度。然後,啟動馬達526而使活塞525、軸體524以及軸體524上所吸附的封杯1及蓋2繞著其中心軸α而旋轉,同時,將雷射光L透過反射鏡529而照射至蓋2的周壁21的緣端附近之部位(圖24)。雷射光L的照射,係使照射位置沿著蓋2的周壁21巡迴複數周回(例如二周)而續行。其結果為,可將呈鍔狀之薄片20的殘部23,從蓋2的開口部切除。從蓋2切離的薄片20的殘部23,係之後被吸引而去除。   [0059] 壓接單元H,係接續於上記的蓋加工工程,負責將蓋2的周壁21從外側方往內側方按壓,並將蓋2的周壁21的內面對封杯1的周壁11的外面進行壓接的壓接工程。如圖25乃至圖27所示,於壓接單元H中,用來按壓蓋2的周壁21所需的壓接機構533,係沿著Y軸方向而從側方,移動至旋轉台522的軸體524上所吸附的封杯1及蓋2的附近(圖26)。壓接機構533係具有:將封杯1及蓋2予以圍繞的方式而配置的複數個(圖示例子中係為三個)壓接轉子534、和內藏於各壓接轉子534的加熱器535,和支持這些壓接轉子534及加熱器535的轉子支持體536。壓接轉子534係可分別繞著鉛直軸而旋動。加熱器535,係負責提高壓接轉子534的外周面的溫度。轉子支持體536,係將使所支持的各壓接轉子534朝向該當轉子支持體536的中央而水平移動,並可使其從中央遠離地做水平移動的氣動夾頭,作為元件。   [0060] 在壓接工程中,以使得轉子支持體536的中央的正下方會有封杯1及蓋2存在的方式,將壓接機構533予以定位,使轉子支持體536所支持的各壓接轉子534的外周面,面對蓋2的周壁的外面。然後,藉由轉子支持體536所具備的氣動夾頭,使各壓接轉子534朝向轉子支持體536的中央而位移(圖27)。亦即,使各壓接轉子534的外周面接觸於蓋2的周壁21的外面,且藉由這些壓接轉子534將蓋2的周壁21從外側方夾住。然後,將吸附著封杯1及蓋2的旋轉台522的軸體524做旋轉驅動,使被壓接轉子534所夾住的蓋2及封杯1繞著該中心軸α而旋轉。藉此,可透過壓接轉子534而將蓋2的周壁21一面加溫而一面朝封杯1的周壁11進行按壓。   [0061] 一旦蓋2的周壁21對封杯1的周壁11的壓接結束,將成形品3、4以封杯1及蓋2包覆而完成了包裝錠,則驅動氣動夾頭而使各壓接轉子534朝從轉子支持體536的中央遠離之方向位移,從各壓接轉子534所致之夾壓,釋放封杯1及蓋2。其後,壓接機構533係退避至原位置。又,旋轉台522的軸體524係下降,且移送體514係上升。此時,由於活塞525是對軸體524相對性地往上方位移,因此將封杯1的底壁12吸附於軸體524的尖端面的負壓會消失。此外,雖然移送體514之上面的軸孔515的開口的周緣上所卡合的薄片20的殘部23已經被從蓋2切離,但蓋2的周壁21之外徑亦即已完成之包裝錠的外徑係比移送體514的軸孔515的內徑略大,因此已完成之包裝錠係不會掉入軸孔515內,而會以從移送體514的上面往上方外露之狀態而被支持同時與移送體514一起上升。   [0062] 此外,於壓接單元H中,將壓接轉子534進行加溫的加熱器535並非必須。亦可不加溫壓接轉子534,只要可使蓋2的周壁21對封杯1的周壁11做充分而強固地接著,則不需要將加熱器535內藏於壓接轉子534。   [0063] 甚至,壓接單元H及壓接工程本身也非必須。於蓋成形工程中,將已被插入有成形品3、4的封杯1當作公模而從薄片來形成蓋2時,若蓋2的周壁21的內面可對封杯1的周壁11的外面充分且強固地接著,則亦可不實施壓接工程,可廢除包含壓接機構533在內的壓接單元H。   [0064] 最後,移送機構513的移送體514,係將已完成的包裝錠,移送至本製造裝置(的包裝膠囊成形機500)中的產品回收位置為止。然後,使已完成的包裝錠,落入設置在該當產品回收位置的排出口(滑槽)。   [0065] 在封杯1的成形工程中,使薄片10對公模507做相對性移動,使薄片10抵接於公模507,使具有容積之封杯1從薄片10突出。在上記實施形態中,雖然是先固定好公模507然後使薄片10朝向公模507移動(下降),但亦可先固定好薄片10然後使公模507朝向薄片10移動,亦可使薄片10及公模507雙方朝彼此接近的方向而移動。   [0066] 又,在蓋2的成形工程中,係使薄片20對已插入有成形品3之封杯1做相對性移動,藉由將該當封杯1當作公模而抵接於薄片20,使具有容積之封杯的蓋2從薄片20突出。在上記實施形態中,雖然是先固定好已插入有作為公模之成形品3之封杯1然後使薄片20朝向該當封杯1移動(下降),但亦可先固定好薄片20然後使已插入有成形品3之封杯1朝向薄片20移動,亦可使薄片20及封杯1雙方朝彼此接近的方向而移動。   [0067] 在本實施形態的一種封裝容器1、2的製造方法中,係從將已收納有內容物3之封杯1的開口部加以密封所需之蓋2的材料,且為在對封杯1的周壁11的外面做密接的作為內面之一側預先設有接著層24的薄片20,來形成覆蓋封杯1的蓋2,同時,將前記蓋2的周壁21的內面對前記封杯1的周壁11的外面做接著。本實施形態中的封裝容器1、2的製造裝置,係具備:蓋成形單元F,係從將已收納有內容物3之封杯1的開口部加以密封所需之蓋2的材料,且為在對封杯1的周壁11的外面做密接的作為內面之一側預先設有接著層24的薄片20,來形成覆蓋封杯1的蓋2。   [0068] 若依據本實施形態,則藉由蓋成形工程及/或壓接工程中所產生的熱,封杯1與蓋2就可隔著預先設在薄片20上的接著層24而被確實地接著。封杯1與蓋2做接合的時點上不需要重新塗布接著劑,因此作為接著劑的溶媒而被使用的乙醇或水不會造成封杯1中所收納之內容物30變質或是細菌的繁殖。也可避免伴隨接著劑的塗布而來的水溶性的封杯1或蓋2的溶損。   [0069] 在蓋成形工程中,係以收納有內容物3之封杯1為公模,在將該封杯1的開口部朝向前記薄片20側之狀態下使薄片20對封杯1做相對性移動,將薄片20抵接於該當封杯1,藉此,使具有容積之蓋2從薄片20突出。藉此,蓋2的成形的同時,可將蓋2對封杯1進行接合。而且,可利用蓋2成形之際所產生的熱,促進封杯1與蓋2之接合。   [0070] 甚至,只要藉由前記蓋2的成形後的壓接工程,來負責將蓋2的周壁21的內面對前記封杯1的周壁11的外面進行壓接的壓接工程,則可使蓋2對封杯1更進一步強固地接著。   [0071] 作為封杯1及蓋2之材料的薄片10、20係分別為以熱可塑性高分子材料為素材的薄膜,例如以烴丙基甲基纖維素或聚乙烯醇為素材的薄膜。在製造醫藥的製劑的情況下,係為可在服用之人的體內溶解的素材的薄膜。   [0072] 此外,在上記實施形態中,係於負責粉體壓縮工程的粉體壓縮成形機600中,也實施將內容物的成形品3插入至封杯1的插入工程。但是,亦可不是在粉體壓縮成形機600內,也可考慮在粉體壓縮成形機600外,實施插入工程。   [0073] 此情況下,是將負責插入工程的插入單元D,設在例如包裝膠囊成形機500內。如圖28乃至圖30所示,在該當插入單元D中,是在將複數個成形品3沿著上下方向做直列而保持的彈匣516中,儲留著預先成形之成形品3。該成形品3,係使用粉體壓縮成形機600而將粉體30予以壓縮而成,亦可使用異於成形機600的粉體壓縮成形機而將粉體30予以壓縮而成。無論如何,將用來成形該當成形品3所需之粉體30進行壓縮的工程係相當於粉體壓縮工程,為了實施該當粉體壓縮工程而使用的粉體壓縮成形機係相當於粉體壓縮單元。   [0074] 經過封杯成形單元A中的封杯成形工程後,在軸孔515中收容封杯1而加以支持的移送機構513的移送體514,係將該當封杯1不是移送至粉體壓縮成形機600內的插入單元C而是移送至包裝膠囊成形機500內的插入單元D為止。此時,移送體514,係從載置著彈匣516的基台517的下方進入(圖29)。在基台517中的彈匣516之附近的位置,係鑿通有上下方向貫通的投入口518。投入口518的內徑,係略等於將封杯1予以支持的基台517的上端部的外徑。從基台517的下方進入的移送體514的軸孔515及封杯1的中心軸α,係與基台517的投入口518同軸。其後,使移送體514上升,將其上端部從下方插入至基台517的投入口518。此時,移送體514的上面的高度係與基台517的上面的高度大略位於相同平面。   [0075] 接著,位於彈匣516之最下部的驅動體519,從沿著X軸方向的側方進出至投入口518及移送體514的正上方的位置為止。驅動體519,係為具有應插入至封杯1之成形品3一個份或較其稍小之厚度的平板之構件,其端部係鑿通有上下方向貫通的捕捉孔520。捕捉孔520的內徑,係略等於成形品3的外徑。當驅動體519的捕捉孔520,是位於被保持在彈匣516中的複數個成形品3之正下方時,這些複數個成形品3之中的最下位的一個係會落下至捕捉孔520內而被捕捉孔520所捕捉。然後,一旦該驅動體519進出到投入口518及移送體514的正上方的位置,則捕捉孔520及其所捉住的成形品3的中心軸,與移送體514的軸孔515及封杯1的中心軸α係為同軸。   [0076] 在此狀態下,使退到投入口518之上方的棒狀的推桿521下降,以其尖端部(下端部)將捕捉孔520內的成形品3從上方戳入封杯1內(圖30)。結果,在封杯1內係有成形品3被插入。   [0077] 將成形品4推入至封杯1後的推桿521在上升後,驅動體519係退避至原位置。此時,驅動體519的捕捉孔520,係回到彈匣516中所被保持之複數個成形品3之正下方的位置,迎接新的一個成形品3。將已被插入有成形品3的封杯1予以支持的移送體514係下降,其上端部係從投入口518脫離。然後,移送體514係移動至封杯加工單元E中的旋轉台522的上方。   [0078] 此外,本發明不限於以上所詳述之實施形態。本發明所述之製劑的製造方法及製造方法,係對調配複數種類之粉體的調配劑、或將複數種類之粉體予以積層的積層劑的製造上,也是有用的。例如,藉由在一個封杯1中插入複數個成形品,可簡便地製造將二種以上之有效成分封入至封杯1內而成的調配劑或積層劑。又,亦可考慮在封杯1內,封入一個或複數個成形品,以及未被壓縮成形的粉體或薄膜等。   [0079] 在封杯1,亦可不是插入將粉體所壓縮而成的成形品,而是將未被壓縮成形的粉體、液體、溶膠、膠體等予以充填,將該封杯1以蓋2予以密封而製造製劑,也是可被容許的。重點是,以封杯1及蓋2為元件的包裝膠囊的內容物,係不限定於粉體所壓縮而成的成形品。   [0080] 上記實施形態中的構成粉體壓縮單元B的成形機係為竪型式粉體壓縮成形機600,但作為構成粉體壓縮單元的成形機亦可採用旋轉式粉體壓縮成形機。   [0081] 在上記實施形態中,用來進行從料帶502切出作為封杯1之材料的薄片10的加工所需之雷射裝置、用來進行將薄片10的剩餘部位予以切除之加工所需之雷射裝置、用來進行從封杯1的開口緣切除殘部13之加工所需之雷射裝置、用來進行從料帶530切出作為蓋2之材料的薄片20的加工所需之雷射裝置、用來進行將薄片20的剩餘部位予以切斷之加工所需之雷射裝置、及用來進行從蓋2的開口緣切除殘部23之加工所需之雷射裝置係為共通,都使用了在切除殘部13、23的加工之際用來改變雷射光L的光軸之方向的反射鏡(或稜鏡)529。但是,這些加工並不一定要使用同一台雷射裝置來執行,當然亦可藉由實裝複數個雷射裝置來提升生產能力。   [0082] 又,藉由本發明所述之製造方法或製造裝置所製造的對象,係不限定於醫藥。亦可將本發明利用於醫藥以外的製劑的製造。   [0083] 除此以外,各部的具體構成或具體的處理程序,係在不脫離本發明之宗旨的範圍內,可作各種變形。[0020] Hereinafter, embodiments of the present invention will be described with reference to the drawings. [0021] <Outline> First, an outline of the method of manufacturing the packaging containers 1 and 2 and the preparation in the present embodiment will be described. In this embodiment, the molded product 3 obtained by compressing the powder 30 is wrapped with the base material sheets 10 and 20 packaged in the packaging containers 1 and 2 to manufacture a packaging ingot. The packaging ingot is formed by inserting the contents into the sealed cup 1 having a volume formed from the sheet 10, for example, a molded product 3 obtained by compressing the powder 30, and the opening of the sealed cup 1 is opened from the sheet 20 A preparation in which the formed lid 2 is sealed. The term "powder" refers to the concept of aggregates of minute individuals, including aggregates of so-called granules such as granules, and aggregates of powder smaller in size than granules. As shown in FIG. 1 and FIG. 2, the manufacturing method of the packaging containers 1 and 2 and the preparation according to the present embodiment includes a sealing cup forming process, and forming the sealing cup 1 required for housing the molded product 3 from the sheet 10. ; And powder compression process, which is a process of compressing powder 30 to form a molded article 3 as the content of a packaging ingot; and insertion process, which inserts the molded product 3 into the sealing cup 1; and sealing cup processing, which starts from The sealing cup 1 in which the molded product 3 has been inserted, and the remaining portion 13 of the sheet 10 is cut off; and the sealing process is to seal the opening of the sealing cup 1 in which the molded product 3 has been inserted by the sheet 20. [0022] In the sealing cup forming process, as shown in FIG. 1 (I), the sheet 10 as the material of the sealing cup 1 is relatively moved to the male mold 507, and the sheet 10 is abutted to the male mold 507. So that the sealing cup 1 having a volume protrudes from the current sheet 10. Thereby, the sealing cup 1 provided with the shape of the bottom wall 12 and the peripheral wall 11 standing up along the outer periphery of the bottom wall 12 is formed. [0023] The sheet 10 as the material of the sealing cup 1 is a thin film using a thermoplastic polymer material. In the case where the preparation to be manufactured is a medicine for oral administration, a film used as a raw material such as a hydrocarbylmethyl cellulose or polyvinyl alcohol can be used as the sheet 10 for the medicine. In addition, when a thin film-like sheet 10 is manufactured, a plasticizer may be added to the material of the sheet 10. In addition, the material of the sheet 10 may be blended with, for example, titanium oxide as a sunscreen agent for suppressing the contents of the packaging ingot from being exposed to light. [0024] Then, as shown in FIG. 1 (II), the remaining portion of the excess sheet 10 attached to the sealing cup 1 is substantially removed by, for example, laser processing of irradiating the sheet with laser light L. At this stage, from the opening of the seal cup 1, in other words, from the edge of the peripheral wall 11, the stubs 13 of the 锷 -shaped sheet 10 extending to the outside will remain, and the seal cup 1 will become like a hat. shape. The wavelength of the laser light L used when the sheet 10 is cut must be a wavelength that allows the sheet 10 to absorb the energy of the laser light L. In the case where the transparency of the sheet 10 is high, a laser with a long wave is used, for example, a wavelength of 10. 6 μm or 9. 4 μm carbon dioxide laser. [0025] In the powder compression process, a tip portion (upper end portion) of the lower pestle 603 is inserted into the mortar hole 601 provided in the upper and lower penetration holes of the mortar table 602 from below, and the mortar hole 601 is filled with After the powder 30 of the component (if the medicine is a medicine), insert the tip (lower end) of the upper pestle 604 into the mortar hole 601 from above, and place the mortar hole 601 through the upper pestle 604 and the lower pestle 603. The inner powder 30 is compressed to obtain a molded product 3 (see FIGS. 10 to 12). The compacted powder 30 is an active ingredient and components other than the active ingredient (if the tablet is a medicine, it is an excipient, a binder, a disintegrant, a moisturizer, a stabilizer, a preservative, etc.) mixture. In addition, the molded product 3 manufactured in the powder compression process does not necessarily have sufficient hardness as a tablet that can be circulated on the market, as long as it can be stored in the period before the cup 1 is sealed, What is necessary is just to guarantee the shape-retaining property to the extent that the amount or shape of the powder 30 is maintained. That is, in the powder compacting process, the powder 3 can be compressed with the molded product 3 having sufficient hardness as a tablet, and the powder can also be compressed with pressure to the extent that the molded product 3 is easily damaged or disintegrated. Body 30. [0026] In the inserting process, as shown in FIG. 1 (III), the molded product 3 obtained through the powder compression process is inserted into the sealing cup 1 from above with the opening of the sealing cup 1 facing upward. . [0027] In the sealing cup processing process, as shown in FIG. 1 (IV), the stub-like stub 13 extending outward from the opening of the sealing cup 1 is removed. At this time, while the sheet 10 containing the sealing cup 1 is rotated around the axis α, the laser light L with the optical axis oriented in a direction that intersects (especially orthogonally) the extending direction of the rotation axis α is The portion near the edge of the peripheral wall 11 of the sealing cup 1 protruding from the stub portion 13 of the sheet 10 is irradiated with laser processing from the outside. With this processing, small pieces of the thin sheet 10 are not left at the opening edge of the sealing cup 1, and the remaining part 13 of the sheet 10 can be cut off from the sealing cup 1 surely, and the sealing cup 1 having only the bottom wall 12 and the peripheral wall 11 can be completed. . The laser L used in the cutting of the stub 13 of the sheet 10 is, for example, a wavelength of 10. 6 μm or 9. 4 μm carbon dioxide laser. [0028] The sealing process includes: a cap forming process, which forms the cover 2 required to seal the opening portion of the sealing cup 1 from the sheet 20; and a cap processing process, which removes the remainder of the sheet 20 from the formed cap 2 23; and the crimping process, applying pressure to the peripheral wall 21 of the cover 2 to crimp it to the peripheral wall 11 of the sealing cup 1. In the lid forming process, as shown in FIG. 2 (V), the sealing cup 1 with the molded product 3 inserted is used as a male mold, and the sheet 20 as the material of the lid 2 is relatively moved to the sealing cup 1, By abutting the sheet 20 to the sealing cup 1, the lid 2 having a shape covering the sealing cup 1 is protruded from the sheet 20. As a result, a cover 2 having a shape including a top wall 22 and a peripheral wall 21 hanging down along the outer periphery of the top wall 22 is formed. At the same time, the inner surface of the peripheral wall 21 of the lid 2 is in close contact with the outer surface of the peripheral wall 11 of the sealing cup 1, and the top wall 22 of the lid 2 closes the opening of the sealing cup 1. [0029] The sheet 20 as the material of the lid 2 is also a thin film using a thermoplastic polymer material in the same manner as the sheet as the material of the sealing cup 1. If the preparation to be manufactured is a medicine for oral administration, a material that can be dissolved in the body of the person taking the medicine, such as a film of hydrocarbon propyl methyl cellulose or polyvinyl alcohol, is used as the sheet 20 . In addition, when a thin film-like sheet 20 is manufactured, a plasticizer may be blended in the material of the sheet 20. In addition, the material of the sheet 20 may be blended with, for example, titanium oxide as a sunscreen agent for suppressing the contents of the packaging ingot from being exposed to light. [0030] In some cases, the sheet 20 as the material of the cover 2 is provided on the inner surface side which is in close contact with the outer surface of the peripheral wall 11 of the cup 1, and an adhesive layer 24 is provided in advance (see FIGS. 19 and 20). The adhesive layer 24 is composed of, for example, copovidone, methacrylic acid copolymer LD, ethyl acrylate-methyl methacrylate copolymer, polyvinylpyrrolidone, or aminoalkyl methacrylate copolymer E. More specifically, copovidone or the like as an adhesive is dissolved in ethanol or water together with a plasticizer, and this is applied to a sheet 20, that is, a hydrocarbyl methyl cellulose film or a polyvinyl alcohol film, and then dried. This constitutes the adhesive layer 24. When applying the adhesive to the sheet 20, a plate type composed of a metal mesh or the like may be used, and the adhesive may be applied in countless dots. Alternatively, instead of dispersing and applying the adhesive in a solvent, it is conceivable to produce a thin film using the adhesive as a material, and apply the film to one side of the sheet 20, that is, a hydrocarbylmethyl cellulose film, or the like. Heating and pressure are performed on one side to form the bonding layer 24. The next layer 24 does not necessarily need to be provided on the entire surface of the sheet 20, as long as it is provided at least on the peripheral wall 21 of the sheet 20 (the inner surface of which is next to the outer wall of the seal cup 1) and the top wall 22 (the lower surface of which is On the upper surface of the molded product 3). [0031] In the process of forming the lid 2 by the lid forming process, the inner surface of the peripheral wall 21 of the lid 2 is joined to the outer surface of the peripheral wall 11 of the sealing cup 1. In the case where the adhesive layer 24 is provided on the sheet 20 of the material of the lid 2, by heating the sheet 20 at this time, the inner layer of the peripheral wall 21 of the lid 2 and the peripheral wall 11 of the sealing cup 1 will be heated by the adhesive layer 24. Follow up outside. [0032] Then, as shown in FIG. 2 (VI), the remaining portion of the excess sheet 20 attached to the cover 2 is roughly removed by, for example, laser processing of irradiating the sheet 20 with laser light L. At this stage, from the opening of the cover 2, in other words, from the edge of the peripheral wall 21, the stub-shaped sheet 20 extending to the outside is left with the remainder 23, and the cover 2 is shaped like a hat. As mentioned above, the laser L used in the cutting of the sheet 20 is, for example, a wavelength of 10. 6 μm or 9. 4 μm carbon dioxide laser. [0033] Next, in the cap processing process, as shown in FIG. 2 (VII), the stub-like stub 23 extending outward from the opening of the cap 2 is removed. At this time, while the sheet 20 containing the lid 2 is rotated around the coaxial α of the sealing cup 1 and the like, the optical axis is oriented in a direction that intersects (especially orthogonally) the extending direction of the rotation axis α. The laser light L is subjected to laser processing for irradiation from the outer side at a portion near the edge end of the peripheral wall 21 of the cover 2 protruding from the stub portion 23 of the sheet 20. At this time, by matching the focal point of the laser light L to the peripheral wall 21 of the cover 2 and / or adjusting the output of the laser light L, the peripheral wall 11 of the sealing cup 1 can be prevented from being cut by the laser light L. Damage other than that. With this processing, a small piece of the excess sheet 20 does not remain on the opening edge of the cover 2, and the remaining part 23 of the sheet 20 can be reliably cut off from the cover 2, and the cover 2 having only the top wall 22 and the peripheral wall 21 can be completed. The peripheral wall 11 of the cup 1 and the peripheral wall 21 of the lid overlap to complete the peripheral wall of the packaging ingot, and therefore the side surfaces of the molded product 3 that has been packaged will not be exposed. As mentioned above, the laser L used in the cutting of the sheet 20 is, for example, a wavelength of 10. 6 μm or 9. 4 μm carbon dioxide laser.  [0034] Furthermore, In the crimping process, The peripheral wall 21 of the cover 2 is pressed from the outside to the inside. The inner surface of the peripheral wall 21 of the lid 2 faces the outer surface of the peripheral wall 11 of the cup 1 and is crimped. but, The implementation of the crimping project is not necessary. When the lid 2 is formed from a sheet in a lid forming process, If the inner surface of the peripheral wall 21 of the cover 2 faces the outer surface of the peripheral wall 11 of the sealing cup 1 as a sufficiently strong adherent, It is not necessary to perform such crimping.  [0035] Through the above project, Packaging ingots as shown in Figure 2 (VIII), That is, a preparation in which the molded product 3 compressed into the powder 30 is wrapped with a packaging capsule formed by a cup 1 and a lid 2, Was done.  [0036] As shown in FIG. 3, A manufacturing apparatus used for carrying out the method for manufacturing a preparation according to this embodiment, It is a packaging capsule forming machine 500 for forming cups 1 and lids 2 from sheets, A combination with a powder compression molding machine 600 for forming the molded product 3 from the powder 30. the following, The manufacturing apparatus of this embodiment will be described in detail.  [0037] <Cup forming unit> Cup forming unit A, Inside the packaging capsule forming machine 500, Responsible for the cup forming process of forming the cup 1 with a volume from the sheet 10. As shown in Figure 4 to Figure 9, In the cup forming unit A, First of all, At the sheet cut-out position 501, From the strip 502 of the sheet 10 as the material of the sealing cup 1, A round-shaped sheet 10 having a predetermined size is cut out. The sheet 10 is cut out by For example, the laser light L is irradiated along the contour of the cut sheet 10. then, The cut sheet 10, The forming position 503 is held and fixed by the Baoding mechanism 504. Baoding Agency 504, By means of a pair of ring-shaped hollow members 505, 506, the sheet 10 is clamped up and down. The lower member 506 of the Baoding mechanism 504, Can be moved between the sheet cutting position 501 and the forming position 503, Collect the sliced sheet 10 at the sheet cutting position 501, It is then transported to the forming position 503.  [0038] In the forming position 503, Male mold 507 protruding upwards and having a slightly cylindrical shape, Stands under the Baoding mechanism 504. then, Looking at the opposite side of the male mold 507 from the sheet 10, That is, from above the sheet 10, Built-in fan duct 508, A warm wind is blown on the sheet 10 to warm the thermoplastic sheet 10. then, Baoding mechanism 504 that holds and holds sheet 10, Towards the male model 507, The sheet 10 is brought into contact with the tip surface (upper end surface) of the male mold 507 (FIG. 5). Simultaneously, From the perspective of the sheet 10, the male mold 507 side is decompressed to a lower pressure than the air duct 508 side. Specifically, the atmosphere under the sheet 10 is attracted, The sheet 10 is attracted to the tip (upper end) of the male mold 507 (FIG. 6). result, The sealing cup 1 having a volume corresponding to the shape of the tip portion of the male mold 507, It protrudes from above the sheet 10 and is formed. The sealing cup 1 has, The peripheral wall 11 having a cylindrical shape along the outer peripheral surface of the tip portion of the male mold 507, And a bottom wall 12 having a shape along the tip surface of the male mold 507.  [0039] After the sealing cup 1 is protruded from the sheet 10 and formed, The Baoding mechanism 504 lifts the sheet 10 away from the male mold 507 while holding the sheet 10. Next, The male model 507 retreated sharply downward, The cup sealer 509 enters directly below the Baoding mechanism 504 from the side along the X-axis direction. Sealing cup turning machine 509, Is from a horizontal support axis 510 which can rotate around a horizontal axis, The suction arm 511 protrudes along its orthogonal direction, The opening part of the sealing cup 1 facing downward is turned upward, and the sealing cup 1 is inverted. The tip of the suction arm 511, It has the same shape as the tip of the male model 507. Inside the cup sealer 509, The suction path 512 required to attract the atmosphere is formed, The suction passage 512 is opened at the tip surface of the suction arm 511. Sealing cup turning machine 509, In a posture in which the suction arm 511 faces upward, It is positioned directly below the sealing cup 1. then, The Baoding mechanism 504 holding the sheet 10 is lowered again, The tip of the suction arm 511 is inserted into the sealing cup 1. In this state, once the suction path 512 is attracted to make it negative, Then, the sheet 10 containing the sealing cup 1 is adsorbed on the tip surface of the adsorption arm 511.  [0040] Next, Irradiate the remaining portion of the excess sheet 10 connected to the opening of the sealing cup 1 with laser light L, Cut off the rest of the area (Figure 7). at this time, Along the Z-axis direction orthogonal to the rest of the sheet 10, that is, the up-down direction (from above in the example shown in the figure), The laser light L is irradiated at a position slightly deviating outward from the opening edge of the sealing cup 1, Simultaneously, The irradiation position of the laser light L, Scanning is performed by moving in an arc shape along a contour β of a circular shape larger than the diameter of the opening edge of the seal cup 1. With this, The sheet 10 is cut along the trajectory of the irradiation position of the laser light L. In the opening of the sealing cup 1 from which the remaining part of the sheet 10 has been cut off, The stub-shaped sheet 10 that is bent from the peripheral wall 11 of the sealing cup 1 and protrudes outward is retained. The rest of the sheet 10 cut from the sealing cup 1, The system was later attracted and removed.  [0041] After the remaining part of the slice is excised, Half-rotate the suction arm 511 and the horizontal support shaft 510 holding the seal cup 1 so that the suction arm 511 faces downward to turn the seal cup 1 upside down. Simultaneously, Displace the suction arm 511 and the horizontal support axis 510 sideways along the X-axis direction. The sealing cup 1 with the opening portion facing upward is carried to a position directly above the transfer mechanism 513. then, The transfer body 514 of the transfer mechanism 513 is raised toward the suction arm 511. Formed in the transfer body 514, An opening shaft hole 515 is made on it. The inner diameter of the shaft hole 515, From the top of the transfer body 514 to a depth that is slightly equal to the height inch method of the peripheral wall 11 of the sealing cup 1 (for example, from the top of the transfer body 514 to a depth of about 5 mm), Is slightly the outer diameter of the peripheral wall 11 of the sealing cup 1, However, the portion below it is narrower than the outer diameter of the peripheral wall of the sealing cup 1. Once the transfer body 514 rises, The tip portion of the suction arm 511 facing downward and the sealed cup 1 absorbed thereon are received in the shaft hole 515 of the transfer body 514 (FIG. 8). in this way, By stopping the suction of the suction path 512 of the cup sealing and turning machine 509, The seal cup 1 can be delivered from the suction arm 511 to the transfer body 514. at this time, The crotch 13 extending outward from the opening edge of the sealing cup 1, The peripheral edge of the opening of the shaft hole 515 is engaged with the upper surface of the transfer body 514. Since then, The transfer body 514 descends and moves away from the suction arm 511, The cup sealer 509 is returned to the original position (Fig. 9). also, The male model 507 is raised toward the original position. A transfer mechanism 513 of the cup 1 is housed in the shaft hole 515 of the transfer body 514, Afterwards, the sealing cup 1 is used to tour the units B, C, E, F, G, The H method is transferred and works.  [0042] <Powder Compression Unit> Powder Compression Unit B, Inside the powder compression molding machine 600, Responsible for the powder compression process of compressing the powder 30 to obtain the molded product 3 to be filled in the sealing cup 1. As shown in Figure 10 to Figure 12, In the powder compression unit B, First of all, In the mortar hole 601 of the mortar table 602 having the mortar hole 601 penetrating up and down, Insert the tip (upper end) of the lower pestle 603 from below, And adjusting the height of the lower pestle 603, In order to ensure that the required volume of the powder 30 is filled in the mortar hole 601. at this time, The upper pestle 604 facing the mortar hole 601 rises from above, The area around the mortar hole 601 on the mortar table 602 is opened. then, The filling device (feeding chute) 605 is moved along the upper surface of the mortar table 602 so as to cover the mortar hole 601 of the mortar table 602 from above, The mortar hole 601 is filled with powder 30 (FIG. 11). Filling device 605 for filling powder 30, Retreat from the area around the mortar hole 601 on the mortar table 602.  [0043] Next, Lowering the upper pestle 604 and inserting the tip portion (lower end portion) into the mortar hole 601 from above, The tip of the upper pestle 604 and the tip of the lower pestle 603 press the powder 30 in the mortar hole 601 and compress it. A molded product 3 is formed (FIG. 12).  [0044] <Insertion Unit> Insertion Unit C, Is located in the powder compression molding machine 600, Shares the same components with the powder compression unit B, Responsible for inserting the molded product 3 obtained by compressing the powder 30 into the sealing cup 1. Figure 10, As shown in Figures 13 and 14, In the inserting unit C, After the compression of the powder 30 is completed by the powder compression process, Lower the lower pestle 603, The tip surface (upper end surface) is pulled away from the lower surface of the molded product 3. at this time, The molded product 3 formed by compressing the powder 30 is left in the mortar hole 601. then, Raise the upper pestle 604 and the mortar table 602, A space that is opened laterally along the Y-axis direction is secured below the mortar hole 601. then, In that space, A transfer body 514 that accommodates the seal cup 1 in the shaft hole 515 and supports the transfer mechanism 513 of the current seal cup 1, It will enter from below along the Y-axis direction (Figure 13). The shaft hole 515 of the transfer body 514 entering the current space and the central axis α of the sealing cup 1, Is coaxial with the central axis of the molar hole 601 of the molar table 602, That is, the center axes of both sides are the same when viewed in the Z-axis direction in the up-down direction.  [0045] Next, Hold transfer body 514 slightly upward, Lower the upper pestle 604, Molded product 3 retained in the mortar hole 601, Poke into the seal cup 1 from above (Figure 14). result, A molded product 3 is inserted into the sealing cup 1. then, Make the upper pestle 604 rise again, Simultaneously, Lowering the transfer body 514 slightly, The transfer body 514 is retracted from the space below the mortar table 602. Once the transfer body 514 retreats, Then the mortar table 602 descends to its original position, The tip of the upper pestle 604 is pulled out from the mortar hole 601. also, The lower pestle 603 will also rise, The tip portion will enter the mortar hole 601 again.  [0046] <Cup sealing processing unit> Cup sealing processing unit E, Is located inside the packaging capsule forming machine 500, Responsible for the process of sealing the cup by removing the remainder 13 of the flaky sheet 10 protruding outward from the opening of the sealing cup 1 into which the molded product 3 has been inserted. As shown in Figure 15 to Figure 17, In the cup sealing processing unit E, First of all, The turntable 522 required to rotate the sealing cup 1 of the processing object about its central axis α, Access is made toward the processing position 523 (Fig. 16). The rotary table 522 series has: The shaft body 524 and the piston 525, which are extended in the up-down direction and can be rotated about the central axis, that is, the vertical axis. And a motor 526 as a drive source for rotationally driving the shaft 524. Formed inside the shaft body 524: Negative pressure passages 527 extending in the up-down direction, And a negative pressure generating space 528 located below the negative pressure passage 527 and communicating to the negative pressure passage 527. Negative pressure path 527, It is open at the tip surface (upper end surface) of the shaft body 524. Piston 525, It is inserted into the negative pressure generating space 528 from below. Shaft 524 and piston 525, Such as spline joints, For shaft body 524, The piston 525 is relatively displaceable along the up and down direction, On the other hand, When the shaft 524 is rotated about the central axis, the piston 525 and the shaft 524 are integrated and rotated. The volume of the negative pressure generating space 528, It is expanded by the piston 525 moving relative to the shaft 524 up and down, compression. also, The piston 525 is directly connected to the output shaft of the motor 526.  [0047] The transfer body 514 of the transfer mechanism 513 that supports the seal cup 1 with the molded product 3 inserted therein, The system moves above the rotary table 522. at this time, The central axis of the shaft body 524, With the axial hole 515 of the transfer body 514 and the central axis α of the sealing cup 1, The system is coaxial. then, Once the transfer body 514 is lowered, The tip (upper end) of the shaft body 524 is received in the shaft hole 515 of the transfer body 514, Its tip face will abut or be very close to the bottom wall 12 of the cup 1. In this state, Once the shaft 524 is raised, Then, the tip of the shaft 524 protrudes upwards from the top of the transfer body 514, The bottom wall 12 of the sealing cup 1 is lifted so that the remaining part 13 of the sealing cup 1 and the sheet 10 floats from the upper surface of the transfer body 514. Simultaneously, The piston 525 connected to the motor 526 is relatively displaced downward with respect to the shaft 524, Increasing the volume of the negative pressure generating space 528 to generate negative pressure, This negative pressure passes through the negative pressure passage 527 so that the bottom wall 12 of the cup 1 is attracted to the tip surface of the shaft 524.  [0048] In the cup sealing process, In order to remove the stub-like stub 13 attached to the opening of the sealing cup 1, Near the edge end (upper end) of the peripheral wall 11 of the sealing cup 1, From the side along the X axis, Irradiate the laser light L. therefore, A mirror (or 45 ° right angle 稜鏡) 529 that reflects the laser light L and turns its optical axis to the X-axis direction, It is arrange | positioned at the height of the peripheral wall 11 of the sealing cup 1 which floats from the upper surface of the transfer body 514 from the X-axis direction surface. then, Start the motor 526 to make the piston 525, The shaft 524 and the sealing cup 1 attracted thereto rotate around its central axis α, Simultaneously, The laser light L is transmitted through the reflecting mirror 529 to a portion near the edge of the peripheral wall 11 of the sealing cup 1 (FIG. 17). The irradiation of laser light L, The irradiation position is continued along the peripheral wall 11 of the sealing cup 1 for several weeks (for example, two weeks). As a result, The stubs 13 of the thin sheet 10 can be made, It is cut out from the opening of the sealing cup 1. The stubs 13 of the sheet 10 cut from the sealing cup 1, The system was later attracted and removed.  [0049] After removing the remaining portion 13 of the sheet 10 from the sealing cup 1, The shaft 524 descends, And the transfer body 514 rises. at this time, Since the piston 525 is relatively upwardly displaced from the shaft 524, Therefore, the negative pressure that attracts the bottom wall 12 of the sealing cup 1 to the tip surface of the shaft 524 disappears. In addition, The remainder 13 of the sheet 10 that is engaged on the periphery of the opening of the shaft hole 515 in the upper surface of the transfer body 514 has been cut away from the sealing cup 1, But as explained earlier, The portion below the shaft hole 515 of the transfer body 514, Its inner diameter is narrower than the outer shape of the peripheral wall 11 of the sealing cup 1. therefore, The sealing cup 1 will not sink into the shaft hole 515, The supported body 514 is lifted together with the transferred body 514 at the same time. After the shaft body 524 is detached downward from the shaft hole 515 of the transfer body 514, The turntable 522 is retracted from the processing position 523.  [0050] <Sealing unit> Sealing unit, Inside the packaging capsule forming machine 500, Sealing process for sealing the opening portion of the sealing cup 1 in which the molded product 3 has been inserted with the sheet 20. In this embodiment, The sealing unit includes a cap forming unit F, Cap processing unit G and crimping unit H.  [0051] Cap forming unit F, The same constituent elements are shared with the cup forming unit A, Cover forming work for forming a cover 2 from the sheet 20 to seal the opening of the cup 1 is required. As shown in Figure 18 to Figure 22, In the cap forming unit F, The thinner lowers the transfer body 514 of the transfer mechanism 513 that supports the cup 1 after the remainder 13 of the sheet 10 has been cut off, Then, it is moved to a position below the Baoding mechanism 504 where the molding position 503 is located. on the other hand, At the sheet cut-out position 501, From the strip 530 of the sheet 20 as the material of the cover 2, a circular sheet 20 of a predetermined size is cut out, The cut sheet 20 is held and fixed at the forming position 503 by the fixing mechanism 504 (FIG. 19). at this time, The lower member 506 of the Baoding mechanism 504, Attach the cut sheet 20 at the sheet cutting position 501, It is then transported to the forming position 503. Cut out of the sheet 20 as the material of the cover 2, The cutting out of the sheet 10 as the material of the sealing cup 1 is performed by the same laser processing. In addition, With the sheet 20 as the material of the cover 2 facing downward, An adhesive layer 24 is provided in advance.  [0052] Next, From below the transfer body 514, A support shaft 531 is inserted into the shaft hole 515 of the current transfer body 514. Support shaft 531, When the cover 2 is formed from a sheet, it serves as a male model, It plays the role of supporting the cup 1 in which the molded product 3 has been inserted from below. Inside the support shaft 531, A suction path 532 is formed to attract the atmosphere. The suction passage 532 is opened at a tip surface (upper end surface) of the support shaft 531. Support shaft 531, The tip surface is raised to a height slightly equal to the upper surface of the transfer body 514, With this, Raise the bottom wall 12 of the sealing cup 1 to a height that is slightly equal to the upper surface of the transfer body 514, The sealing cup 1 is exposed upward from the shaft hole 515 of the feed body 514. then, In this state, the suction path 532 is attracted and becomes negative pressure. The bottom wall 12 of the sealing cup 1 is fixed to the tip surface of the support shaft 531 by suction.  [0053] Then, Viewed from the sheet 20 and opposite to the sealing cup 1, That is above the sheet 20, Built-in fan duct 508, The thermoplastic sheet 20 is heated by blowing warm air on the sheet 20. Since then, Baoding mechanism 504 that holds and holds the sheet 20, Falling towards the sealing cup 1 as a male mold, The sheet 20 is brought into contact with the opening edge (upper edge) of the seal cup 1 and the upper surface of the molded product 3 inserted in the seal cup 1 (FIG. 20). at the same time, When viewed from the sheet 20, the side of the cup 1 is decompressed to a lower pressure than the side of the air pipe 508, Specifically, the atmosphere under the sheet 20 is attracted, Thereby, the sheet 20 is attracted to the sealing cup 1 (and the upper surface of the transfer body 514) (FIG. 21). result, A lid 2 having a volume with a shape corresponding to the outer shape of the peripheral wall 11 of the cup 1 and the outer shape of the upper surface of the molded product 3, It is formed by protruding upward from the sheet 20. The cover 2 has: The peripheral wall 21 having a cylindrical shape along the outer periphery of the peripheral wall 11 of the sealing cup 1, And a top wall 22 that follows the shape of the upper surface of the molded product 3. then, When the cover 2 is formed, The inner surface of the peripheral wall 21 of the cover 2 is joined to the outer surface of the peripheral wall 11 of the cup 1, The lower surface of the top wall 22 is joined to the upper surface of the molded product 3 inserted in the sealing cup 1. especially, As the sheet 20 of the cover 2 faces downward, That is, when the adhesive layer 24 is provided in advance on the surface facing one side of the cup 1 and the molded product 3, When the cover 2 is formed, The inner surface of the peripheral wall 21 will follow the outer surface of the peripheral wall 11 of the cup 1. Simultaneously, The lower surface of the top wall 22 having the adhesive layer 24 is attached to the upper surface of the molded product 3 inserted in the sealing cup 1.  [0054] After the cover 2 is protruded from the sheet 20 and formed, Stop the suction of the suction path 532 of the support shaft 531, Desorption of the bottom wall 12 of the sealing cup 1 to the tip surface of the support shaft 531 is cancelled. then, The Baoding mechanism 504 holds and lifts the sheet 20 on which the cover 2 is formed, The transfer body 514 also follows the Baoding mechanism 504 and rises. at this time, The sealing cup 1 and the lid 2 are joined together, The sheet 20 integrated with the cover 2 is sandwiched by Baoding mechanism 504, The rest of the sheet 20 is placed on top of the transfer body 514, Therefore, the cup 1 and the lid 2 are also raised together with the Baoding mechanism 504 and the transfer body 514 in a state exposed from the upper surface of the transfer body 514 upward.  [0055] Next, Irradiate the remaining part of the excess sheet 20 connected to the opening of the cover 2 with laser light L, The remaining part was removed (Fig. 22). at this time, Along the up-down direction orthogonal to the rest of the sheet 20, Irradiate the laser light L at a position slightly biased to the outside from the opening edge of the cover 2, Simultaneously, The irradiation position of the laser light L is also scanned by moving in a circular arc along a contour β of a circular shape having a diameter larger than the opening edge of the cover 2. With this, The sheet 20 is cut along the trajectory of the irradiation position of the laser light L. The opening of the cover 2 after the remaining part of the sheet 20 is cut off remains, The stub-shaped sheet 20 is folded from the peripheral wall 21 of the cover 2 and protrudes outward. The remainder 23 of the sheet 20, Is the peripheral edge of the opening of the shaft hole 515 engaged with the upper surface of the transfer body 514, The sealing cup 1 and the lid 2 are held in a state protruding from the upper surface of the transfer body 514. The rest of the sheet 20 cut off from the cover 2, The system was later attracted and removed.  [0056] After the remaining part of the sheet 20 is excised, The transfer body 514 supporting the cup 1 and the lid 2 is slightly lowered, Simultaneously, The support shaft 531 is largely retracted downward.  00 [0057] Cover processing unit G, The same constituent elements are shared with the cup sealing processing unit E, Responsible for the processing of the cap, which is responsible for cutting off the stubs 23 of the 锷 -shaped sheet 20 that protrude outward from the opening of the lid 2 that seals the cup 1. As shown in Figures 23 and 24, In the cap processing unit G, First of all, The transfer body 514 supporting the transfer mechanism 513 of the cup 1 and the lid 2 is moved toward the processing position 523 (FIG. 23). The transfer body 514, Stands at a position above the turntable 522. and, The turntable 522 is moved in and out to the processing position 523. At processing position 523, The central axis of the shaft body 524 of the rotary table 522, With the shaft hole 515 of the transfer body 514, The central axis α of the cup 1 and the lid 2 is coaxial. then, Once the transfer body 514 is lowered, The tip of the shaft body 524 is received in the shaft hole 515 of the transfer body 514, Its tip face will abut or be very close to the bottom wall 12 of the cup 1. In this state, Once the shaft 524 is raised, Then, the tip of the shaft 524 protrudes upwards from the top of the transfer body 514, The bottom wall 12 of the sealing cup 1 is lifted to make the sealing cup 1 The lid 2 and the remaining portion of the sheet are lifted from the upper surface of the transfer body 514. Simultaneously, The piston 525 connected to the motor 526 is relatively displaced downward with respect to the shaft 524, Increasing the volume of the negative pressure generating space 528 to generate negative pressure, This negative pressure passes through the negative pressure passage 527 so that the bottom wall 12 of the cup 1 is attracted to the tip surface of the shaft 524.  [0058] In the cap processing process, In order to remove the stub-like stub 23 connected to the opening of the cover 2, Near the edge (lower end) of the peripheral wall 21 of the cover 2, From the side along the X axis, Irradiate the laser light L. therefore, A mirror 529 that reflects the laser light L so that its optical axis turns to the X-axis direction, It is arrange | positioned at the height of the peripheral wall 21 of the cover 2 which floats from the upper surface of the transfer body 514 from the X-axis direction surface. then, Start the motor 526 to make the piston 525, The shaft body 524 and the sealing cup 1 and the cover 2 adsorbed on the shaft body 524 rotate around their central axis α, Simultaneously, The laser light L is transmitted through the reflecting mirror 529 to a portion near the edge end of the peripheral wall 21 of the cover 2 (FIG. 24). The irradiation of laser light L, The irradiation position is continued along the peripheral wall 21 of the cover 2 for several weeks (for example, two weeks). As a result, The stubs 23 of the thin sheet 20 can be made, It is cut out from the opening of the cover 2. Residual part 23 of the sheet 20 cut away from the cover 2, The system was later attracted and removed.  [0059] Crimping unit H, It is the cover processing project continued from the above. Responsible for pressing the peripheral wall 21 of the cover 2 from the outside to the inside, The inner surface of the peripheral wall 21 of the cover 2 faces the outer surface of the peripheral wall 11 of the sealing cup 1 and a crimping process is performed. As shown in Figure 25 to Figure 27, In the crimping unit H, A crimping mechanism 533 required to press the peripheral wall 21 of the cover 2, From the side along the Y axis, It moves to the vicinity of the seal cup 1 and the lid 2 which are adsorbed on the shaft 524 of the rotary table 522 (FIG. 26). The crimping mechanism 533 has: A plurality of crimping rotors 534, which are arranged so as to surround the sealing cup 1 and the lid 2 (three in the illustrated example), And a heater 535 built into each crimp rotor 534, And a rotor support 536 that supports the crimped rotor 534 and the heater 535. The crimping rotor 534 can rotate around a vertical axis, respectively. Heater 535, The system is responsible for increasing the temperature of the outer peripheral surface of the crimp rotor 534. Rotor support 536, The supported crimp rotors 534 are moved horizontally toward the center of the rotor support 536. And it can be moved horizontally from the center of the pneumatic chuck, As a component.  [0060] In the crimping process, In such a manner that the seal cup 1 and the lid 2 exist directly below the center of the rotor support 536, Position the crimping mechanism 533, The outer peripheral surface of each of the crimped rotors 534 supported by the rotor support 536, It faces the outside of the peripheral wall of the cover 2. then, With the pneumatic chuck included in the rotor support 536, Each pressure-contact rotor 534 is displaced toward the center of the rotor support 536 (FIG. 27). that is, Contact the outer peripheral surface of each crimp rotor 534 with the outer surface of the peripheral wall 21 of the cover 2, The peripheral wall 21 of the cover 2 is sandwiched from the outside by these crimping rotors 534. then, The shaft 524 of the rotary table 522 that holds the sealing cup 1 and the lid 2 is rotationally driven, The lid 2 and the seal cup 1 held by the crimping rotor 534 are rotated around the central axis α. With this, The peripheral wall 21 of the cover 2 can be pressed toward the peripheral wall 11 of the sealing cup 1 while the peripheral wall 21 of the cover 2 is heated by the pressure-contacting rotor 534.  [0061] Once the pressing of the peripheral wall 21 of the lid 2 to the peripheral wall 11 of the sealing cup 1 is completed, Formed product 3, 4The packaging ingot is completed by covering the cup 1 and the lid 2. The pneumatic chuck is driven to displace each crimping rotor 534 in a direction away from the center of the rotor support 536, From the pinching caused by each crimping rotor 534, Release the seal cup 1 and cover 2. Since then, The crimping mechanism 533 is retracted to the original position. also, The shaft 524 of the rotary table 522 is lowered, And the transfer body 514 rises. at this time, Since the piston 525 is relatively upwardly displaced from the shaft 524, Therefore, the negative pressure that attracts the bottom wall 12 of the sealing cup 1 to the tip surface of the shaft 524 disappears. In addition, Although the remaining part 23 of the sheet 20 engaged on the periphery of the opening of the shaft hole 515 on the upper surface of the transfer body 514 has been cut off from the cover 2 However, the outer diameter of the peripheral wall 21 of the cover 2, that is, the outer diameter of the finished packaging ingot is slightly larger than the inner diameter of the shaft hole 515 of the transfer body 514. Therefore, the finished packaging ingot will not fall into the shaft hole 515, On the other hand, it is supported in a state exposed from the upper surface of the transfer body 514 and rises together with the transfer body 514 at the same time.  [0062] In addition, In the crimping unit H, The heater 535 for heating the pressure-bonded rotor 534 is not necessary. It is also possible to crimp the rotor 534 without heating, As long as the peripheral wall 21 of the lid 2 can be sufficiently and firmly adhered to the peripheral wall 11 of the sealing cup 1, It is not necessary to include the heater 535 in the crimp rotor 534.  [0063] Even, The crimping unit H and the crimping process itself are not necessary. In the cap forming process, Will have inserted molded products 3, When the sealing cup 1 of 4 is used as a male mold and the lid 2 is formed from a sheet, If the inner surface of the peripheral wall 21 of the lid 2 can be sufficiently and firmly adhered to the outer surface of the peripheral wall 11 of the cup 1, It is not necessary to carry out crimping works, The crimping unit H including the crimping mechanism 533 can be eliminated.  [0064] Finally, The transfer body 514 of the transfer mechanism 513, Is the finished packaging ingot, Transfer to the product collection position in this manufacturing apparatus (packaging capsule molding machine 500). then, Make finished packaging ingots, It falls into a discharge port (chute) provided at the current product recovery position.  [0065] In the forming process of the cup 1, Relatively move the sheet 10 to the male mold 507, Making the sheet 10 abut against the male mold 507, The sealing cup 1 having a volume is caused to protrude from the sheet 10. In the above embodiment, Although the male mold 507 is fixed first, and then the sheet 10 is moved (fallen) toward the male mold 507, However, it is also possible to fix the sheet 10 first and then move the male mold 507 toward the sheet 10, Both the sheet 10 and the male mold 507 may be moved toward each other.  [0066] Again, In the forming process of the lid 2, The sheet 20 is relatively moved to the sealing cup 1 into which the molded product 3 has been inserted, By using the current sealing cup 1 as a male mold and abutting on the sheet 20, The lid 2 having a volume-sealing cup is projected from the sheet 20. In the above embodiment, Although the sealing cup 1 in which the molded product 3 as a male mold has been inserted is fixed first, and then the sheet 20 is moved (dropped) toward the current sealing cup 1, However, it is also possible to fix the sheet 20 first and then move the sealing cup 1 into which the shaped product 3 has been inserted toward the sheet 20, You may move both the sheet | seat 20 and the sealing cup 1 in the direction which approaches each other.  [0067] A packaging container 1 according to this embodiment In the manufacturing method of 2, Is the material of the lid 2 required to seal the opening of the seal cup 1 in which the contents 3 have been stored, In addition, a sheet 20 having an adhesive layer 24 is provided in advance on one side of the inner surface which is tightly adhered to the outer surface of the peripheral wall 11 of the sealing cup 1, To form the lid 2 covering the sealing cup 1, Simultaneously, The inner side of the peripheral wall 21 of the preface cover 2 faces the outer side of the peripheral wall 11 of the preface seal cup 1. Packaging container 1 in this embodiment 2 manufacturing equipment, Department has: Cover forming unit F, Is the material of the lid 2 required to seal the opening of the seal cup 1 in which the contents 3 have been stored, In addition, a sheet 20 having an adhesive layer 24 is provided in advance on one side of the inner surface which is tightly adhered to the outer surface of the peripheral wall 11 of the sealing cup 1, To form a lid 2 covering the sealing cup 1.  [0068] According to this embodiment, The heat generated during the cap forming process and / or the crimping process, The sealing cup 1 and the lid 2 can be reliably adhered through the adhesive layer 24 provided in advance on the sheet 20. When the sealing cup 1 and the lid 2 are joined, it is not necessary to reapply the adhesive at the point. Therefore, ethanol or water used as a solvent for the adhesive does not cause deterioration of the contents 30 contained in the sealing cup 1 or proliferation of bacteria. It is also possible to avoid dissolution of the water-soluble sealing cup 1 or the lid 2 accompanying the application of the adhesive.  [0069] In the cap forming process, The sealing cup 1 containing the content 3 is used as a male model. The sheet 20 is relatively moved to the seal cup 1 with the opening of the seal cup 1 facing the preparatory sheet 20 side. The sheet 20 is abutted against the current sealing cup 1, With this, The cover 2 having a volume is caused to protrude from the sheet 20. With this, While the cover 2 is being formed, The lid 2 can be joined to the sealing cup 1. and, The heat generated when the lid 2 is formed can be used, Promote the joint between the cup 1 and the lid 2.  [0070] Even, As long as the crimping process after forming the cap 2 is performed, To be responsible for the crimping process of crimping the inner side of the peripheral wall 21 of the cover 2 to the outer face of the peripheral wall 11 of the seal cup 1 in advance, Then, the lid 2 can be further firmly bonded to the sealing cup 1.  [0071] Sheet 10 as a material for sealing cup 1 and lid 2, The 20 series are thin films made of thermoplastic polymer materials. For example, a film made of hydrocarbyl methyl cellulose or polyvinyl alcohol. In the case of manufacturing pharmaceutical preparations, It is a thin film of materials that can be dissolved in the body of the person taking it.  [0072] Furthermore, In the above embodiment, In the powder compression molding machine 600 responsible for powder compression engineering, The inserting process of inserting the molded article 3 of the content into the sealing cup 1 is also performed. but, It may not be in the powder compression molding machine 600, It can also be considered outside the powder compression molding machine 600, Implement the insertion project.  [0073] In this case, Is the insertion unit D that will be responsible for the insertion project, It is provided in, for example, a packaging capsule forming machine 500. As shown in Figure 28 to Figure 30, In the proper insertion unit D, The magazine 516 holds a plurality of molded products 3 aligned in the vertical direction. The preformed molded product 3 is stored. The molded product 3, The powder 30 is compressed by using a powder compression molding machine 600, The powder 30 may be compressed by using a powder compression molding machine different from the molding machine 600. anyway, The process of compressing the powder 30 required for forming the molded product 3 is equivalent to the powder compression process. The powder compression molding machine used for carrying out this powder compression process corresponds to a powder compression unit.  [0074] After the cup forming process in the cup forming unit A, The transfer body 514 of the transfer mechanism 513 that supports and seals the cup 1 in the shaft hole 515, The current sealing cup 1 is not transferred to the insertion unit C in the powder compression molding machine 600 but to the insertion unit D in the packaging capsule molding machine 500. at this time, Transfer body 514, It enters from below the base 517 on which the magazine 516 is placed (FIG. 29). Near the magazine 516 in the abutment 517, The system is provided with an input port 518 penetrating vertically. The inside diameter of the entrance 518, The diameter is slightly equal to the outer diameter of the upper end of the abutment 517 supporting the sealing cup 1. The shaft hole 515 of the transfer body 514 entering from below the base 517 and the central axis α of the sealing cup 1, It is coaxial with the input port 518 of the abutment 517. Since then, Raising the transfer body 514, The upper end portion is inserted into the input port 518 of the base 517 from below. at this time, The height of the upper surface of the transfer body 514 is substantially on the same plane as the height of the upper surface of the base 517.  [0075] Next, The driving body 519 located at the bottom of the magazine 516, It goes in and out from the side along the X-axis direction to a position directly above the input port 518 and the transfer body 514. Drive body 519, It is a member having a flat plate having one part of the molded product 3 to be inserted into the sealing cup 1 or a thickness smaller than that, A catching hole 520 penetrating in an up-and-down direction is chiseled at an end portion thereof. The inner diameter of the capture hole 520, It is slightly equal to the outer diameter of the molded product 3. When the capture hole 520 of the driving body 519, When it is located directly below the plurality of molded products 3 held in the magazine 516, The lowest one of the plurality of molded products 3 falls into the capture hole 520 and is captured by the capture hole 520. then, Once the driving body 519 enters and exits to the position directly above the input port 518 and the transfer body 514, The central axis of the capture hole 520 and the molded product 3 it captures, The axis hole 515 of the transfer body 514 and the central axis α of the seal cup 1 are coaxial.  [0076] In this state, Lower the rod-shaped putter 521 retracted above the input port 518, The molded product 3 in the capture hole 520 is pierced into the sealing cup 1 from above with its tip (lower end) (FIG. 30). result, A molded product 3 is inserted into the sealing cup 1.  [0077] After the molded product 4 is pushed into the sealing cup 1, the push rod 521 is raised, The driving body 519 is retracted to the original position. at this time, The capture hole 520 of the driving body 519, Returns to the position directly below the plurality of molded products 3 held in the magazine 516, We meet a new molded product 3. The transfer body 514 supporting the sealing cup 1 in which the molded product 3 has been inserted is lowered, The upper end is detached from the input port 518. then, The transfer body 514 is moved above the rotary table 522 in the cup sealing processing unit E.  [0078] Furthermore, The invention is not limited to the embodiments described in detail above. The manufacturing method and manufacturing method of the preparation according to the present invention, It is a compounding agent for compounding multiple types of powders, Or in the manufacture of a laminating agent in which plural kinds of powders are laminated, Also useful. E.g, By inserting a plurality of shaped articles into one sealing cup 1, A preparation or a laminating agent in which two or more active ingredients are enclosed in the sealing cup 1 can be easily manufactured. also, It can also be considered in the sealing cup 1, Sealing one or more molded products, As well as powders or films that have not been compressed.  [0079] In sealing cup 1, It is not necessary to insert a molded product obtained by compressing the powder, Instead, the powder is not compressed, liquid, Sol, Filling with colloids, etc. The sealing cup 1 is sealed with a lid 2 to manufacture a preparation, It is also permissible. The point is, The contents of the packaging capsules with cup 1 and lid 2 as components, It is not limited to a molded product obtained by compressing a powder.  [0080] The molding machine constituting the powder compression unit B in the above embodiment is a vertical powder compression molding machine 600, However, as the molding machine constituting the powder compression unit, a rotary powder compression molding machine may be used.  [0081] In the above embodiment, A laser device for processing the sheet 10 as a material of the sealing cup 1 from the tape 502, A laser device for processing the remaining portion of the sheet 10, A laser device for cutting the stub 13 from the opening edge of the sealing cup 1, A laser device for processing the sheet 20 as a material of the cover 2 from the tape 530, A laser device for processing the remaining part of the sheet 20, And the laser device for cutting the stub 23 from the opening edge of the cover 2 is common, Are used in the removal of remnants 13, 23 is a mirror (or 稜鏡) 529 for changing the direction of the optical axis of the laser light L during processing. but, These processes do not have to be performed using the same laser device, Of course, you can also increase production capacity by installing multiple laser devices.  [0082] Again, An object manufactured by the manufacturing method or manufacturing device according to the present invention, Department is not limited to medicine. The present invention can also be used for the manufacture of preparations other than medicine.  [0083] In addition, The specific composition or specific processing procedures of each department, Within the scope not departing from the spirit of the present invention, Can make various deformations.

[0084][0084]

1‧‧‧封杯1‧‧‧Seal Cup

10‧‧‧薄片10‧‧‧ sheet

11‧‧‧周壁11‧‧‧ Zhoubi

13‧‧‧薄片的殘部13‧‧‧ stub

2‧‧‧蓋2‧‧‧ cover

20‧‧‧薄片20‧‧‧ sheet

21‧‧‧周壁21‧‧‧Zhou Bi

23‧‧‧薄片的殘部23‧‧‧ stub

24‧‧‧接著層24‧‧‧ Adjacent layer

3‧‧‧內容物(成形品)3‧‧‧Contents (molded product)

F‧‧‧蓋成形單元F‧‧‧Cap forming unit

H‧‧‧壓接單元H‧‧‧Crimping unit

[0019]   [圖1] 本發明之一實施形態的封裝容器及製劑的製造方法之概要的模式圖。   [圖2] 同實施形態的製造方法之概要的模式圖。   [圖3] 同實施形態的封裝容器及製造裝置之全景的斜視圖。   [圖4] 同實施形態的製造裝置的封杯成形單元的斜視圖。   [圖5] 同實施形態的製造裝置的封杯成形單元的側剖面圖。   [圖6] 同實施形態的製造裝置的封杯成形單元的側剖面圖。   [圖7] 同實施形態的製造裝置的封杯成形單元的側剖面圖。   [圖8] 同實施形態的製造裝置的封杯成形單元的側剖面圖。   [圖9] 同實施形態的製造裝置的封杯成形單元的側剖面圖。   [圖10] 同實施形態的製造裝置的粉體壓縮單元及插入單元的斜視圖。   [圖11] 同實施形態的製造裝置的粉體壓縮單元的側剖面圖。   [圖12] 同實施形態的製造裝置的粉體壓縮單元的側剖面圖。   [圖13] 同實施形態的製造裝置的插入單元的側剖面圖。   [圖14] 同實施形態的製造裝置的插入單元的側剖面圖。   [圖15] 同實施形態的製造裝置的封杯加工單元的斜視圖。   [圖16] 同實施形態的製造裝置的封杯加工單元的側剖面圖。   [圖17] 同實施形態的製造裝置的封杯加工單元的側剖面圖。   [圖18] 同實施形態的製造裝置的蓋成形單元的斜視圖。   [圖19] 同實施形態的製造裝置的蓋成形單元的側剖面圖。   [圖20] 同實施形態的製造裝置的蓋成形單元的側剖面圖。   [圖21] 同實施形態的製造裝置的蓋成形單元的側剖面圖。   [圖22] 同實施形態的製造裝置的蓋成形單元的側剖面圖。   [圖23] 同實施形態的製造裝置的蓋加工單元的側剖面圖。   [圖24] 同實施形態的製造裝置的蓋加工單元的側剖面圖。   [圖25] 同實施形態的製造裝置的壓接單元的斜視圖。   [圖26] 同實施形態的製造裝置的壓接單元的側剖面圖。   [圖27] 同實施形態的製造裝置的壓接單元的側剖面圖。   [圖28] 同實施形態的製造裝置的第二插入單元的斜視圖。   [圖29] 同實施形態的製造裝置的第二插入單元的側剖面圖。   [圖30] 同實施形態的製造裝置的第二插入單元的側剖面圖。[0019] FIG. 1 is a schematic diagram showing an outline of a method for manufacturing a packaging container and a preparation according to an embodiment of the present invention. [Fig. 2] A schematic view showing the outline of the manufacturing method of the same embodiment. [Fig. 3] A perspective view of a panoramic view of the packaging container and the manufacturing apparatus in the same embodiment. [Fig. 4] A perspective view of a cup forming unit of the manufacturing apparatus of the same embodiment. [Fig. 5] A side sectional view of a cup forming unit of the manufacturing apparatus of the same embodiment. [Fig. 6] A side sectional view of a cup forming unit of the manufacturing apparatus of the same embodiment. [Fig. 7] A side sectional view of a cup forming unit of the manufacturing apparatus of the same embodiment. [Fig. 8] A side sectional view of a cup forming unit of the manufacturing apparatus of the same embodiment. [Fig. 9] A side sectional view of a cup forming unit of the manufacturing apparatus of the same embodiment. [Fig. 10] A perspective view of a powder compression unit and an insertion unit of the manufacturing apparatus of the same embodiment. [FIG. 11] A side sectional view of a powder compression unit of the manufacturing apparatus of the same embodiment. [Fig. 12] A side sectional view of a powder compression unit of the manufacturing apparatus of the same embodiment. [Fig. 13] A side sectional view of an insertion unit of the manufacturing apparatus of the same embodiment. [Fig. 14] A side sectional view of an insertion unit of the manufacturing apparatus of the same embodiment. [Fig. 15] A perspective view of a cup sealing processing unit of the manufacturing apparatus of the same embodiment. [FIG. 16] A side sectional view of a cup sealing processing unit of the manufacturing apparatus of the same embodiment. [FIG. 17] A side sectional view of a cup sealing processing unit of the manufacturing apparatus of the same embodiment. [Fig. 18] A perspective view of a lid forming unit of the manufacturing apparatus of the same embodiment. [FIG. 19] A side sectional view of a lid forming unit of the manufacturing apparatus of the same embodiment. [FIG. 20] A side sectional view of a lid forming unit of the manufacturing apparatus of the same embodiment. [Fig. 21] A side sectional view of a lid forming unit of the manufacturing apparatus of the same embodiment. [FIG. 22] A side sectional view of a lid forming unit of the manufacturing apparatus of the same embodiment. [FIG. 23] A side sectional view of a cap processing unit of the manufacturing apparatus of the same embodiment. [FIG. 24] A side sectional view of a cap processing unit of the manufacturing apparatus of the same embodiment. [Fig. 25] A perspective view of a crimping unit of the manufacturing apparatus of the same embodiment. [FIG. 26] A side sectional view of a crimping unit of the manufacturing apparatus of the same embodiment. [FIG. 27] A side sectional view of a crimping unit of the manufacturing apparatus of the same embodiment. [FIG. 28] A perspective view of a second insertion unit of the manufacturing apparatus of the same embodiment. [FIG. 29] A side sectional view of a second insertion unit of the manufacturing apparatus of the same embodiment. [FIG. 30] A side sectional view of a second insertion unit of the manufacturing apparatus of the same embodiment.

Claims (7)

一種封裝容器的製造方法,係從將已收納有內容物之封杯的開口部加以密封所需之蓋的材料,且為在對封杯的周壁的外面做密接的作為內面之一側預先設有接著層的薄片,來形成覆蓋封杯的蓋,同時,將前記蓋的周壁的內面對前記封杯的周壁的外面做接著。A method for manufacturing a sealed container, which is made of a material for a lid required to seal an opening portion of a sealing cup in which a content has been stored, and is a side of the inner surface of the sealing cup which is tightly sealed on the outer surface of the sealing cup in advance. A sheet with an adhesive layer is provided to form a lid covering the sealing cup, and at the same time, the inner side of the peripheral wall of the pre-cap is facing the outer surface of the peripheral wall of the pre-encapsulating cup. 如請求項1所記載之封裝容器的製造方法,其中,以前記封杯為公模,在將其開口部朝向前記薄片側之狀態下使薄片對封杯做相對性移動,藉由將薄片抵接於封杯以將前記蓋予以成形。The method for manufacturing a sealed container according to claim 1, wherein the sealing cup is a male mold, and the sheet is relatively moved to the sealing cup with the opening portion facing the sheet side, and the sheet is pressed against the sealing cup. It is connected to the sealing cup to shape the cap. 如請求項1所記載之封裝容器的製造方法,其中,在前記蓋的成形後,將蓋的周壁的內面對前記封杯的周壁的外面做壓接。The method for manufacturing a sealed container according to claim 1, wherein after forming the cap, the inner side of the peripheral wall of the cap faces the outer side of the outer wall of the cap cup. 如請求項1所記載之封裝容器的製造方法,其中,使用共聚維酮、甲基丙烯酸共聚物LD、丙烯酸乙酯-甲基丙烯酸甲酯共聚物、聚乙烯吡咯烷酮、或甲基丙烯酸氨基烷基酯共聚物E來構成前記接著層。The method for manufacturing a sealed container according to claim 1, wherein copovidone, methacrylic acid copolymer LD, ethyl acrylate-methyl methacrylate copolymer, polyvinylpyrrolidone, or aminoalkyl methacrylate is used. The ester copolymer E constitutes the preceding adhesive layer. 如請求項4所記載之封裝容器的製造方法,其中,   前記薄片係為以熱可塑性高分子材料為素材的薄膜;   在前記蓋的成形之前,將共聚維酮、甲基丙烯酸共聚物LD、丙烯酸乙酯-甲基丙烯酸甲酯共聚物、聚乙烯吡咯烷酮、或甲基丙烯酸氨基烷基酯共聚物E溶解於乙醇或水然後塗布至前記薄膜並使其乾燥以構成前記接著層。The method for manufacturing a sealed container according to claim 4, wherein: the preform sheet is a film made of a thermoplastic polymer material; 之前 before forming the preform cover, copovidone, methacrylic acid copolymer LD, acrylic acid Ethyl-methyl methacrylate copolymer, polyvinylpyrrolidone, or aminoalkyl methacrylate copolymer E is dissolved in ethanol or water and then applied to the film described above and dried to form the film adhesive layer. 一種封裝容器的製造裝置,係具備:蓋成形單元,係從將已收納有內容物之封杯的開口部加以密封所需之蓋的材料,且為在對封杯的周壁的外面做密接的作為內面之一側預先設有接著層的薄片,來形成覆蓋封杯的蓋。A device for manufacturing a sealed container is provided with a lid forming unit, which is a material for a lid required to seal an opening portion of a sealing cup in which contents have been stored, and is tightly adhered to the outer wall of the sealing cup. A sheet of an adhesive layer is provided in advance as one side of the inner surface to form a lid covering the cup. 如請求項6所記載之封裝容器的製造裝置,其中,前記蓋成形單元,係以前記封杯為公模,在將其開口部朝向前記薄片側之狀態下使薄片對封杯做相對性移動,藉由將薄片抵接於封杯以將前記蓋予以成形。The device for manufacturing a sealed container as described in claim 6, wherein the pre-cap forming unit is a pre-formed sealing cup, and the relative movement of the sheet to the sealing cup is performed with the opening portion facing the pre-sheet side. , The aforesaid cap is formed by abutting the sheet on the sealing cup.
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