201036662 六、發明說明： 【發明所屬之技術領域】 本發明係關於一藥物輸送裝置；特別是能輸 多次劑量藥物的藥物輸送裝置。 、 【先前技術】 市面上有許多使用者可自行設定藥劑量之藥 輸送裝置，其中有許多裝置能多次輸送劑量直^ Ο 〇 物容器空了為止。這些劑量可被固定，或於輸^ 量前被分別設定。 背 大部分具此功能之裝置皆有劑量設定旋鈕位 於裝置之末端，為没定要輸送之劑量而被旋轉或 動。然而轉動對使用者來說並不總是最佳方式， t會降低敏捷度。若使用者患有風濕病，會嚴重的 ϊϊκΐί，量的精確度。由於輸送裝置的設計 多為二狀且5旋轉零件，轉動的機制被廣泛地使用。 某些輸送裝i的其他缺點如一些操作 費力^如將裝置上脖或做準備和/或連續注射Μ 中被其—解決方式在US2’_363 % Μ ^ /1 m 於注射的手動操作柱塞桿，連接驅 動構件作用於在犖物交突、 物輸送構件推瓶塞以便藥物經由藥 及使ί ϊ m二注射針。為使裝置操作方便 構，—齒輪組被置於柱塞桿及驅動 乂!？組可減少操作所需之力。 …、^凡全為手動操作，且無法設定劑量。 【發明内容】 本發明最主要目&炎 缺點，特別提供救現今藥物輸送裝置的 更用者新穎且可憑直覺設定劑量之 4 201036662 藥物輸送裝置。 此目標可由專利範園 發明更佳的實施方式成Α 項的特徵來完成。本 的。 成為此專利範圍附屬項的標 根據本發明的主要觀，點，其 送裝置，包括一瘦長外殼有斟，，在於一藥物輸 藥物容器在外殼内，相對的末端和近端，·一 Ο ❹ 器；一柱塞桿作用於籌接該藥物* 置作用於該柱塞桿使該赶宾物今器内，施力裝 經由藥物輸送構件推出.土:動该瓶塞而將藥物 連接到該柱塞；，以制可鬆開地 時’該柱塞桿處於非藥物制與柱塞桿舊合 :與該柱塞桿脫離，該柱塞以率；| =:機 Ϊΐί 口 = 包括一手動操作“經由：：痩 ^口‘向凸出於痩長外殼之縱面； f = = =以致當該柱塞》 端被線性移動相當;設定以;以往= 亥柱塞杯，且當該柱塞桿處於藥物輸送狀 $浐$置作用於該驅動器’該驅動器可從柱 塞杯向外忒近側線性移開。 的使力另:觀點，該施力裝置是由該裝置 根據本發明另一觀點，該施力裝置是彈力裝 置，且在此移開該手動操作裝置會壓縮該彈力裝置。 ，據本發明另一觀點，該驅動器包括第一傳動 f置和手動操作裝置包括第二傳動裝置，兩傳動裝 置互相配合以減少該彈力裝置所需之伸縮力。 根據本發明另一觀點，該驅動器又包括一套 5 201036662 輪合 棘臂 一輪 括棘 包該 管與 套輪 此棘 ，該 移輪 性棘 線一 桿括 塞包 柱桿 該塞 著柱 延該 可且 >50 管臂作 ❹ Ο 排使一觀點，該棘輪臂和該棘輪的每 動:申：時，該套管可對該柱塞桿i -田靜止時，會相互鎖住。 ==本;:ί;ί:棘:;:機== 突起物與棘謝處)及鎖 鈕於外ί t么明另一觀點’該鬆開機制又包括-按 =於:卜破上’該按鈕與鎖件相連接， ：t 寺，該鎖件會被迫與該柱塞桿分離。’、 根據本發明另一觀點，該連接 方向移動’且該鎖件可沿著橫方向移動σ。的縱 定播i發^ί許多優勢。以線性方式來操作劑量机 :f牛，較方疋紐操作劑量設定構件容易。一般而： 士於低敏捷度和精確度的使用者， 移動容易。 踝性移動較旋轉 再者，為使操作更方便，提 少彈力裝置及設定㈣所需之伸縮力齒輪組，可減 a雙重功能的劑量設定構件（如： 彈簧）意指此藥物輸送裝置可長時^ 2 料老造成的連續二二險 開機制與合：的裝置和鬆 功能。 1皇夕数零件部提供非常多的 本發明的這些和其他優勢，狁 附圖將顯而易見。 ^ «以下坪細說明和 6 201036662 【實施方式】 是楢2用中’末端，意指藥物輸送裝置或 件在ί時離使用者最遠的那端。相應之下， 用:最物輸送裝置或是構件在注射時離使 勹把的實鈀方式在圖中為-藥物輸送裝置， 上和:瘦ii卜殼」0有末端與近侧且縱向12延伸。 頸部14)相連_劑仏= Ο Ο 嫘时ίί射ΐ附著於藥物容器。連接裝置可包括 螺2、卡銷、卡榫等等。其他藥物輸送構件可包括 ;Γ射二等/。藥物容11 18與近側相接安裝入 的密閉：器。容器與瓶塞定義了裝藥劑 縱向：ί長ϊίϊ22有近側和末端，可在該外殼内 二;=與6末==二面含有緣， ^ AL ± 浮力裝置28被女排於該杯狀 桿22的面之間。彈力裝置作用於柱塞 器構件心嘴土4;勿2推向該瓶塞2〇，以從藥物容 葦片裝可包括一些不同的施力裝置，如： 曰L彈*、氣壓彈簧、液壓彈簧，或根 據本發明目的任何適用的無電源裝置。 …劑量機制包括驅動器24和-手動操作 裝置36，此刼作地連接該柱塞桿如下。 此驅動器包括第一齒輪裝 此手動操作裝置36是一可線性移動；面=2第 7 201036662 齒輪裝置如至少一棘輪在装 置38如相對面上的按知輪^;表=和操作裝 作用來減少該彈力|置28所需輪裝置相互 此驅動器與套管兩端的轴3 人 此兩軸分別位於驅動II相- S如圖二， 縱向。在軸上至少=;2兩環％'過整二裝” 表面的齒條34合作，可在外耆兩軸和面板刊 36之相反表面36裝有一 &縱向滑動。面板 Ο ❹ :卜殼Ϊ痩長開”9。至少一齒：3=射= i: ί ί ΐ於外殼内部，通常置；面 锻π耵甶且縱向延伸。柱 配合順著柱塞桿的長度延伸二：輪式犬起物42 柱塞的棘輪42與彈性臂44合4 ?長的棘，。 合於器一2 V動44之自由端指向整 該柱塞桿，以致當該鬆；接$ =時’該柱塞桿處“物；;=機 桿延伸穿過中心開口⑽四合4塞 =;開桿糊二r在輪二 末r，”4之近側與鎖二以 物52與柱夷;^是與鎖件聯繫’使得突起 倚著臂標示） 經由此驻罢认主工士山 宰開才干54的末端壁11 上=附置===按_=繫= 端壁11之外殼及按紐58之間來撐起按簧紐。於末 此裝置操作如下。當裝置純使㈣，一合適 8 201036662 二3 ί輸送構件16被附於裝置近側的頸部14。為 j、二劑藥物，裝置必須配備好。此動作可在ς F，1n 物f送狀態時，將按錢沿著瘦; 棘dj末端。由於面板36的至少-第- 成2少一告齒輪32相連接，面板36的移動造 少一笛=輪32的轉動，又因至少一齒輪32盥至 棘輪40間的連接，驅動器24會向裝置 Ο ❹ 動Ξί2。齒輪作用於棘輪上的使用所提供ΪΪ 量設ΐ的需的施力’同時齒輪比也增進了劑 縮，二 = = 柱 (圖-)來主Ϊΐί瘦：開口的特定位置，有標示60 4點km 著開口的劑量指*、斷線、 3踊=定劑量要被輪送，㈣s已被滑至開 塞桿22、m輪儒合的鎖件48鎖於柱 臂44輿;、近侧移動。並且由於驅動器24的 移回原位 的棘輪，合’可預防驅動器24被 位子，於合適的輸送 -^ ^ l：：：l I - f下:使鬆開桿54被往縱向/移 件48。由於彈簣力 無法接觸鎖201036662 VI. Description of the Invention: [Technical Field] The present invention relates to a drug delivery device; in particular, a drug delivery device capable of delivering multiple doses of a drug. [Prior Art] There are many users in the market who can set the drug delivery device of the drug amount. Many of them can deliver the dose directly until the container is empty. These doses can be fixed or set separately prior to delivery. Most devices with this function have a dose setting knob located at the end of the device that is rotated or moved for a dose that is not intended to be delivered. However, rotation is not always the best way for the user, t will reduce agility. If the user suffers from rheumatism, it will be severely ϊϊκΐί, the accuracy of the amount. Since the design of the conveyor is mostly two-shaped and five-rotating parts, the mechanism of rotation is widely used. Other disadvantages of some conveyors such as some operations are such as putting the device on the neck or preparing and/or continuously injecting it in a solution - in US2'_363 % Μ ^ /1 m for manual operation of the plunger The rod, the connecting driving member acts on the sputum in the sputum, the squirting plug of the object conveying member for the drug to pass through the medicine and the needle to be injected. In order to make the device easy to operate, the gear set is placed on the plunger rod and drive 乂!? Groups reduce the force required for operation. ..., ^ all are manually operated, and the dose cannot be set. SUMMARY OF THE INVENTION The present invention is directed to the shortcomings of the present invention, and in particular to provide a more user-friendly and intuitively determinable dose of the drug delivery device. This goal can be accomplished by the features of the patented invention invented into a better embodiment. Ben's. The subject matter of the scope of this patent is based on the main point of the present invention. The delivery device comprises an elongated casing having a crucible in a drug delivery container in the outer casing, opposite ends and proximal ends. a plunger rod acts to raise the drug* to act on the plunger rod to cause the occupant to be pushed out through the drug delivery member. The soil is moved to connect the drug to the bottle. Plunger; when the releasable ground is made, the plunger rod is in a non-medical relationship with the plunger rod: it is disengaged from the plunger rod, and the plunger is at a rate; | =: machine Ϊΐ mouth = includes a manual Operation "via: 痩^口' to protrude from the longitudinal face of the long casing; f = = = so that when the plunger" end is linearly moved equivalent; set to; past = Hai plunger cup, and when the column The plunger is in the drug delivery state. The device is applied to the driver. The driver can be linearly removed from the plunger cup to the proximal side. The force is another: the force applying device is another device according to the present invention. Point of view, the force applying device is a spring device, and the manual operating device is compressed here to be compressed According to another aspect of the present invention, the driver includes a first transmission and a manual operation device including a second transmission, the two transmissions cooperating to reduce the telescopic force required for the elastic device. In view, the driver further includes a set of 5 201036662 wheel bobbin arm and a set of spine packs. The tube and the set wheel have the spine, and the transfer wheel has a rod including a plug column rod. The plug is extended by the column >50 The pipe arm makes a point, the ratchet arm and each movement of the ratchet: when the sleeve is used, the sleeve can lock each other when the plunger rod i is stationary. == 本;: ί ; ί: 棘 : : : : = = = = = = = = = = = = Connected, :t temple, the lock will be forced to separate from the plunger rod. ', according to another aspect of the invention, the connection direction moves 'and the lock can be moved in the lateral direction σ. i send ^ί many advantages. Operate the dosing machine in a linear manner: f cattle, compare the amount of operation of the dose setting component Generally speaking: For users with low agility and precision, it is easy to move. The squat movement is more rotatable, in order to make the operation more convenient, reduce the elastic device and set (4) the required telescopic gear set, can be reduced a dual-function dose setting member (such as: spring) means that the drug delivery device can be used for a long time and the second two-two safety mechanism and loose function. A very large number of these and other advantages of the invention will be apparent from the drawings. ^ «The following detailed description and 6 201036662 [Embodiment] It is the end of the 楢 2, meaning that the drug delivery device or piece is used at ί The farthest end of the person. Correspondingly, use: the most convenient conveying device or the member is separated from the real palladium in the case of injection - in the figure - drug delivery device, upper and: thin ii shell" 0 The ends extend proximally and longitudinally 12. Neck 14) Connected _ Dosing 仏 = Ο Ο ί ίίΐ Attached to the drug container. The attachment means may include a screw 2, a bayonet, a cassette, and the like. Other drug delivery members may include; The drug container 11 18 is attached to the proximal side of the sealed device. The container and the stopper define the longitudinal direction of the filling: ί长ϊίϊ22 has a proximal side and a distal end, and can be inside the outer casing; ==6 and then == two sides contain a margin, ^ AL ± buoyancy device 28 is placed on the cupped rod Between the faces of 22. The elastic device acts on the plunger member's mouth soil 4; do not push 2 to the stopper 2〇 to include a variety of different force applying devices from the drug containing device, such as: 曰L bomb*, gas spring, hydraulic A spring, or any suitable powerless device in accordance with the purpose of the present invention. The dose mechanism includes a driver 24 and a manual operating device 36 that is operatively coupled to the plunger rod as follows. The driver includes a first gear. The manual operating device 36 is linearly movable; the face=2 is 7th 201036662. The gear device, such as at least one ratchet, is on the opposite side of the device 38, such as the counter wheel; Reducing the spring force | Set the required wheel device to each other with the drive shaft and the shaft at both ends of the sleeve. The two shafts are respectively located in the drive phase II-S as shown in Fig. 2, longitudinally. The racks 34 on the shaft at least =; 2 two-ring % 'over-two-fitted' surfaces can cooperate with the outer surface of the outer shaft and the surface 36 of the panel 36 to be longitudinally slid. Panel Ο ❹ : Ϊ Ϊ痩 long open" 9. At least one tooth: 3 = shot = i: ί ί ΐ inside the outer casing, usually placed; face forged 耵甶 and longitudinal extension. The column fits two extensions along the length of the plunger rod: the ratchet 42 of the wheeled canine 42 and the ratchet 42 of the resilient arm 44. The free end of the 2V movement 44 of the device is directed to the plunger rod so that it is loose; when the $= is connected, the rod is at the plunger;; = the rod extends through the central opening (10). =; Open the paste two r at the end of the second round r, "4 near the lock and the second object 52 and the column; ^ is in contact with the lock" so that the protrusion is marked by the arm) The end wall 11 of the mountain slaughter 54 = append === press the _= system = the outer wall of the end wall 11 and the button 58 to hold up the button spring. At the end of the device, the operation is as follows. When the device is pure (4), a suitable 8 201036662 2 3 ί delivery member 16 is attached to the neck 14 proximal to the device. For j, two doses of drugs, the device must be equipped. This action can be carried out when the ς F, 1n object f is sent, and the money will be thinner; Since at least the first-to-two-in-one gear 32 of the panel 36 is connected, the movement of the panel 36 causes a rotation of the flute=wheel 32, and due to the connection of at least one of the gears 32 to the ratchet 40, the driver 24 will Device Ο Ξ Ξ 22. The gears acting on the ratchet provide the required force to set the volume. At the same time, the gear ratio also increases the shrinkage. Two = = column (Fig. -) to the main Ϊΐ thin: specific position of the opening, marked 60 4 The dose indicating the opening of the km km, the broken line, 3 踊 = the fixed dose is to be sent, (4) s has been slid to the opening rod 22, the lock of the m wheel Confucian lock 48 is locked to the column arm 44 舆; mobile. And because the ratchet of the drive 24 is moved back to the original position, the preventable drive 24 is seated, under suitable transport - ^ ^ l::: l I - f: the release lever 54 is moved to the longitudinal/moving member 48 . Unable to touch the lock due to the impeachment force
^3 ^ ^ ^ 52 ^ I 輪42接觸，以致柱塞桿處於藥物輸送狀 9 201036662 ^在藉著彈力裝置28之力向縱向移動去推驅動 ^逾丄且因驅動器24之臂44與柱塞桿22之棘輪 —σ，驅動器24的移動造成至少一齒輪32旋轉， 错欢，面板3 6和按知3 8則被移回原來位子。 塞的移動造成瓶塞2G在藥物容器18 禮二^置侧移動，藉此，一劑藥物被從藥物輸送 & + w中推出。以上描述的操作可執行數次直到荦 物容器18空了為止。 且判樂 Ο 〇 物以上實施方式可依照使用者需求及喜好被修 外殼也許被放在裝置的其他地方，像是 卜=旁邊、樞軸上，或可被壓下或滑動之處。再者， 置H置可能備有可被鬆開的劑量限制装 上。在於瘦長外殼縱面的痩長開口39 赤-ίί?方ί中顯示，劑量限制裝置包括-夹子 “痩ΐ門二' 72可被鬆開的附於痩長外殼縱面 Μ * 上，此瘦長外殼可相應地容納夾子上 ίΐ?、“Τί理+解地，在這方面，許多種類的扣緊 子。7 ,。夾子可預防按鈕38被滑動越出其4立 若一便宜的藥物輸送裝置可以手動操 送，圖九顯不一差異在於彈簧被移 ς = f ff㈣物輸送狀態’驅動器2 4則因手動^ S 動直到所要的劑量被設定完成。為輕ί轉^3 ^ ^ ^ 52 ^ I wheel 42 contacts, so that the plunger rod is in the drug delivery state 9 201036662 ^ in the longitudinal direction by the force of the elastic device 28 to push the drive ^ 丄 and because of the arm 44 of the driver 24 and the plunger The ratchet wheel σ of the rod 22, the movement of the driver 24 causes at least one of the gears 32 to rotate, and the panel 36 and the button 3 are moved back to the original position. The movement of the stopper causes the stopper 2G to move on the side of the drug container 18, whereby a dose of the drug is pushed out from the drug delivery & + w. The above described operation can be performed several times until the sputum container 18 is empty. The above embodiments can be repaired according to user needs and preferences. The casing may be placed elsewhere in the device, such as on the side, on the pivot, or where it can be depressed or slid. Furthermore, the H setting may be provided with a dose limiting device that can be released. The long opening 39 in the longitudinal side of the elongated outer casing shows that the dose limiting device includes - the clip "Tuen Mun II" 72 can be loosened attached to the longitudinal section of the long casing Μ *, which is elongated The outer casing can accommodate the clips accordingly, "Τ 理 + +, in this respect, many types of clasps. 7 . The clip can prevent the button 38 from being slid out of its position. If the cheap drug delivery device can be manually operated, the difference between the two figures is that the spring is moved = f ff (four) the object delivery state 'driver 2 4 is due to manual ^ S Move until the desired dose is set. For light
ί ^ if ITm m m ΐ iJ 起移動，以使劑量被輸送。 驅動盗24 — 圖十顯示一更簡單的奘¥ 或整合於一面板36和一按紐38 °動器24連接於 钕鈕38,使兩者間有連結。 201036662 操作同上述差異。直接連接的差異可與彈力裝置 使用，若後者太弱，使用者能用滑動力來伸縮 彈簧。 以上描述之實施方式和附圖只被視為本發明 二、限制之範例，且本發明在本專利權範圍内可以 多方式修改。 【圖式簡單說明】 本發明在以下詳細說明中，各附圖參照如下： 圖一係根據本發明之侧視圖。 圖二係根據圖一之侧視截面圖。 圖二，根據本發明之劑量設定裝置之詳細視圖。 圖四係根據本發明之劑量設定裝置之詳細視圖。 圖五係根據本發明之劑量設定裝置之詳細視圖。 圖六係根據圖二之侧視截面圖’當劑量已被設定時。 圖七係根據圖二之側視截面圖，當藥劑已被釋出時。 圖八係根據圖一之侧視圖，顯示藥劑量被設定至極 限。 圖九係根據本發明另一實施方式之侧視截面圖。 圖十係根據本發明再另一實施方式之侧視截面圖。 【主要元件符號說明】 10 外殼 16 藥物輸送構件 18 藥劑容器 20 瓶塞 22 柱塞桿 24 驅動器 彈力装置 11 28 201036662 軸 齒輪 棘輪 面板 按紐 瘦長開口 手動操作鬆開機制 申請專利範圍： Ο 有相對的末端^置^包括：一瘦長外殼10 殼10内；藥物輸送^株物容器18被安置於該外 塞桿22用來作用於以二該藥物容器；一柱 施力裝置28用來作田二枭物各器I8内的瓶塞20 ; 推該柱塞桿22經物：=:22對著該瓶塞2〇 -劑量設定機制24 構件16來射出藥劑； 該柱塞桿；一可手 4、36、38可操作地連接 ❹ 30 32 34 36 38 39 46 七 該柱塞桿，以致告鬆開機制可鬆開地連接 塞桿處於非藥物：¾:機，；；桿喃合，該柱 該藥劑設定機制包括：二：:土·，其特徵在於 一瘦長開口 39橫向凸出於庙動^喿，裝置36、38經由 器24、30、32，連接外殼之縱面；一驅動 該柱塞桿22，以操作裝置％、3δ及 時，該手動操作裝置36、38 非藥物輸送狀態 移動相當於設定劑量之驻— -10末端被線性 該柱塞桿22,且當該桂農寺鎖住該驅動器至 動器可從柱塞桿22向外殼近側線性移該驅ί ^ if ITm m m ΐ iJ moves to allow the dose to be delivered. The drive burglary 24 - Fig. 10 shows a simpler 奘 ¥ or integrated into a panel 36 and a button 38 ° 24 connected to the snap button 38 to connect the two. 201036662 Operation differs from the above. The difference in direct connection can be used with the spring device. If the latter is too weak, the user can use the sliding force to retract the spring. The embodiments and the drawings described above are only to be considered as an example of the invention, and the invention can be modified in various ways within the scope of the patent. BRIEF DESCRIPTION OF THE DRAWINGS In the following detailed description, the drawings are referred to the following: FIG. 1 is a side view in accordance with the present invention. Figure 2 is a side cross-sectional view according to Figure 1. Figure 2 is a detailed view of the dose setting device in accordance with the present invention. Figure 4 is a detailed view of a dose setting device in accordance with the present invention. Figure 5 is a detailed view of a dose setting device in accordance with the present invention. Figure 6 is a side cross-sectional view according to Figure 2 when the dose has been set. Figure 7 is a side cross-sectional view according to Figure 2 when the medicament has been released. Figure 8 is a side view of Figure 1, showing that the dose is set to the limit. Figure 9 is a side cross-sectional view of another embodiment of the present invention. Figure 10 is a side cross-sectional view of still another embodiment of the present invention. [Main component symbol description] 10 Housing 16 Drug delivery member 18 Drug container 20 Cork 22 Plunger rod 24 Actuator elastic device 11 28 201036662 Axis gear ratchet panel button thin and long opening manual operation release mechanism Patent application scope: Ο Relative The end portion includes: a thin outer casing 10 in the casing 10; a drug delivery device container 18 is disposed on the outer plug rod 22 for acting on the two drug containers; and a column applying device 28 is used for the field two a stopper 20 in the device I8; pushing the plunger rod 22 through the object: =: 22 against the stopper 2 〇 - dose setting mechanism 24 member 16 to eject the medicament; the plunger rod; a handle 4; 36, 38 operatively connected ❹ 30 32 34 36 38 39 46 seven the plunger rod, so that the release mechanism releasably connects the plug stem to the non-drug: 3⁄4: machine;;; rod merging, the column The medicament setting mechanism comprises: two: soil, characterized in that a thin opening 39 is laterally protruded from the temple, and the devices 36, 38 are connected to the longitudinal surface of the outer casing via the devices 24, 30, 32; Rod 22, in time to operate the device %, 3δ, the manual operation The non-drug delivery state of the device 36, 38 is equivalent to the set dose of the -10 end being linearly linear to the plunger rod 22, and when the Guinonsi locks the drive to the actuator, the plunger rod 22 can be moved from the plunger rod 22 to the proximal line of the housing Sexual shift