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TW200500328A - Method for producing optically active α-aminonitrile compound - Google Patents

Method for producing optically active α-aminonitrile compound

Info

Publication number
TW200500328A
TW200500328A TW093109035A TW93109035A TW200500328A TW 200500328 A TW200500328 A TW 200500328A TW 093109035 A TW093109035 A TW 093109035A TW 93109035 A TW93109035 A TW 93109035A TW 200500328 A TW200500328 A TW 200500328A
Authority
TW
Taiwan
Prior art keywords
compound
optically active
producing optically
aminonitrile compound
bisulfite
Prior art date
Application number
TW093109035A
Other languages
Chinese (zh)
Inventor
Masahiko Seki
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of TW200500328A publication Critical patent/TW200500328A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

This invention relates to an industrially advantageous method for producing optically active α-aminonitrile compound, comprising the step of reacting optically active aldehyde compound containing α-unsymmetry carbon or it's salt, in the presence of solvent containing water, with bisulfite compound to obtain a bisulfite addition product of said aldehyde compound, and the step of reacting thus obtained bisulfite addition product with an optionally substituted primary or secondary amine and cyan compound.
TW093109035A 2003-04-02 2004-04-01 Method for producing optically active α-aminonitrile compound TW200500328A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003098713 2003-04-02

Publications (1)

Publication Number Publication Date
TW200500328A true TW200500328A (en) 2005-01-01

Family

ID=33156680

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093109035A TW200500328A (en) 2003-04-02 2004-04-01 Method for producing optically active α-aminonitrile compound

Country Status (3)

Country Link
JP (1) JP4412279B2 (en)
TW (1) TW200500328A (en)
WO (1) WO2004089878A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104592146A (en) * 2015-01-19 2015-05-06 烟台腾辉化工有限公司 Preparation process of L-2-oxothiazolidine-4-carboxylic acid

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103772410B (en) * 2013-12-31 2016-08-31 浙江新和成股份有限公司 A kind of synthetic method of D-biotin
CN103880859B (en) * 2014-03-11 2015-12-09 新发药业有限公司 (3aS, 6aR)-1,3-dibenzyl tetrahydrochysene-4H-thieno-[3,4-d] imidazoles-2,4-(1H) preparation method of-diketone
CN103936759B (en) * 2014-03-11 2016-01-13 新发药业有限公司 (3aS, 6aR)-1,3-dibenzyl-tetrahydrochysene-4H-thieno-[3,4-d] imidazoles-2,4-(1H) simple and convenient process for preparing of-diketone

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5822140B2 (en) * 1979-06-08 1983-05-06 昭和電工株式会社 Production method of β-chloroalanine
WO1994015941A1 (en) * 1993-01-14 1994-07-21 Akzo N.V. α-AMINONITRILES DERIVED FROM AN AMINO SUGAR
NL1007113C2 (en) * 1997-09-25 1999-03-26 Dsm Nv Process for the preparation of optically active 2-amino-omega-oxoalkanoic acid derivatives.
JP3634207B2 (en) * 1999-09-14 2005-03-30 独立行政法人科学技術振興機構 Process for producing optically active α-amino nitrile and α-amino acids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104592146A (en) * 2015-01-19 2015-05-06 烟台腾辉化工有限公司 Preparation process of L-2-oxothiazolidine-4-carboxylic acid

Also Published As

Publication number Publication date
WO2004089878A1 (en) 2004-10-21
JP4412279B2 (en) 2010-02-10
JPWO2004089878A1 (en) 2006-07-06

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