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TR201903887T4 - İnme etkilerini tedavi etme yöntemi. - Google Patents

İnme etkilerini tedavi etme yöntemi. Download PDF

Info

Publication number
TR201903887T4
TR201903887T4 TR2019/03887T TR201903887T TR201903887T4 TR 201903887 T4 TR201903887 T4 TR 201903887T4 TR 2019/03887 T TR2019/03887 T TR 2019/03887T TR 201903887 T TR201903887 T TR 201903887T TR 201903887 T4 TR201903887 T4 TR 201903887T4
Authority
TR
Turkey
Prior art keywords
treating
stroke
effects
subject
cells
Prior art date
Application number
TR2019/03887T
Other languages
English (en)
Inventor
Andrea Koblar Simon
Gronthos Stan
Arthur Agnieszka
Original Assignee
Central Adelaide Local Health Network Inc
Mesoblast Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Central Adelaide Local Health Network Inc, Mesoblast Inc filed Critical Central Adelaide Local Health Network Inc
Publication of TR201903887T4 publication Critical patent/TR201903887T4/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)

Abstract

Mevcut tarifname, beyin fonksiyonunun iyileştirilmesi veya beyin fonksiyon kaybının önlenmesi ve/veya inme geçirmiş bir denekte bir hareket bozukluğunun tedavi edilmesi veya önlenmesi ve/veya beyin nöronlarının yenilenmesi için yöntemler sağlar, yöntem, deneğe STRO-1+ hücreleri ve/veya bunların soyları ve/veya bunlardan türetilmiş çözünebilir faktörler ile zenginleştirilmiş bir hücre popülasyonunun uygulanmasını içerir.
TR2019/03887T 2011-06-03 2012-06-04 İnme etkilerini tedavi etme yöntemi. TR201903887T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161493057P 2011-06-03 2011-06-03

Publications (1)

Publication Number Publication Date
TR201903887T4 true TR201903887T4 (tr) 2019-04-22

Family

ID=47258178

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/03887T TR201903887T4 (tr) 2011-06-03 2012-06-04 İnme etkilerini tedavi etme yöntemi.

Country Status (12)

Country Link
US (2) US20160361362A1 (tr)
EP (2) EP2714058B1 (tr)
JP (1) JP6265890B2 (tr)
KR (2) KR20180126607A (tr)
CN (2) CN112891374A (tr)
AU (2) AU2012262679B2 (tr)
CA (1) CA2837898C (tr)
ES (1) ES2716015T3 (tr)
IL (1) IL229706A0 (tr)
SG (1) SG195128A1 (tr)
TR (1) TR201903887T4 (tr)
WO (1) WO2012162758A1 (tr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012279995C1 (en) 2011-07-06 2019-10-24 Cell Therapy Limited Progenitor cells of mesodermal lineage
WO2019241462A1 (en) * 2018-06-13 2019-12-19 Texas Tech University System Stem cells for the treatment of conditions and diseases
JP2022516449A (ja) * 2018-12-24 2022-02-28 セレキシス エスエー チャイニーズハムスター卵巣細胞における内在性レトロウイルスの特性評価および不活性化
KR20220011621A (ko) * 2019-05-23 2022-01-28 메조블라스트 인터내셔널 에스에이알엘 뇌경색의 기능적 회복
JPWO2021140773A1 (tr) * 2020-01-08 2021-07-15
CN118121725A (zh) * 2022-12-02 2024-06-04 中国科学院深圳先进技术研究院 一种用于评估脑梗死药物疗效的方法

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US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
DE69233013T2 (de) 1991-08-20 2004-03-04 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
DE19939781C2 (de) 1999-08-21 2003-06-18 Schott Glas Skulltiegel für das Erschmelzen oder das Läutern von anorganischen Substanzen, insbesondere von Gläsern und Glaskeramiken
AU2002330131A1 (en) * 2001-09-28 2003-04-07 Goldberg, Eugene, P. Biopolymer and biopolymer-cell compositions for nerve tissue repair
CA2809164C (en) * 2003-04-19 2017-04-18 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Postnatal stem cells and uses thereof
KR101441026B1 (ko) 2004-09-24 2014-10-01 메소블라스트, 아이엔씨. 증폭된 다능성 간엽 전구세포 자손 및 이의 용도
JP5462483B2 (ja) 2005-04-12 2014-04-02 メゾブラスト，インコーポレーテッド 組織非特異的アルカリホスファターゼによる成体多能性細胞の単離
US20080075345A1 (en) 2006-09-20 2008-03-27 Siemens Corporation Research, Inc. Method and System For Lymph Node Segmentation In Computed Tomography Images
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Also Published As

Publication number Publication date
AU2012262679A1 (en) 2013-05-02
EP3513797A1 (en) 2019-07-24
WO2012162758A1 (en) 2012-12-06
JP2014516715A (ja) 2014-07-17
CA2837898C (en) 2020-06-30
KR20180126607A (ko) 2018-11-27
SG195128A1 (en) 2013-12-30
JP6265890B2 (ja) 2018-01-24
KR101920277B1 (ko) 2018-11-20
KR20140068811A (ko) 2014-06-09
ES2716015T3 (es) 2019-06-07
EP2714058A4 (en) 2014-12-03
CN112891374A (zh) 2021-06-04
EP2714058B1 (en) 2018-12-19
US20160361362A1 (en) 2016-12-15
CA2837898A1 (en) 2012-12-06
EP2714058A1 (en) 2014-04-09
IL229706A0 (en) 2014-01-30
CN103826646A (zh) 2014-05-28
AU2016219603A1 (en) 2016-09-15
AU2012262679B2 (en) 2016-05-26
US20210228639A1 (en) 2021-07-29

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