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TR200200724T2 - Use of fatty acid / amino acid soaps to increase the antimicrobial effect of pharmaceutical compositions that can be applied to the skin - Google Patents

Use of fatty acid / amino acid soaps to increase the antimicrobial effect of pharmaceutical compositions that can be applied to the skin

Info

Publication number
TR200200724T2
TR200200724T2 TR2002/00724T TR200200724T TR200200724T2 TR 200200724 T2 TR200200724 T2 TR 200200724T2 TR 2002/00724 T TR2002/00724 T TR 2002/00724T TR 200200724 T TR200200724 T TR 200200724T TR 200200724 T2 TR200200724 T2 TR 200200724T2
Authority
TR
Turkey
Prior art keywords
increase
pharmaceutical compositions
amino acid
antimicrobial effect
skin
Prior art date
Application number
TR2002/00724T
Other languages
Turkish (tr)
Inventor
J. Castillo Ernesto
Howard Gerson Steven
Wehsin Han Wesley
Original Assignee
Alcon Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories, Inc. filed Critical Alcon Laboratories, Inc.
Publication of TR200200724T2 publication Critical patent/TR200200724T2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Yagli asit/amino asidi sabunlari, en azindan bir aktif terkip maddesi, katyonik bir koruyucu ve karboksivinil polimeri, ksantan zamki, polistiren sülfonik asit polimeri veya katyonik degisim reçinesi gibi anyonik bir polielektrolit içeren, cilde sürülebilen farmasötik bilesimlerde antimikrobik etkinin arttirilmasi için kullanilir.Fatty acid / amino acid soaps are used to increase the antimicrobial effect in pharmaceutical compositions containing at least one active ingredient, a cationic preservative and an anionic polyelectrolyte such as carboxyvinyl polymer, xanthan gum, polystyrene sulfonic acid polymer or cationic exchange resin.

TR2002/00724T 1999-09-21 2000-09-11 Use of fatty acid / amino acid soaps to increase the antimicrobial effect of pharmaceutical compositions that can be applied to the skin TR200200724T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39901399A 1999-09-21 1999-09-21

Publications (1)

Publication Number Publication Date
TR200200724T2 true TR200200724T2 (en) 2002-06-21

Family

ID=23577764

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00724T TR200200724T2 (en) 1999-09-21 2000-09-11 Use of fatty acid / amino acid soaps to increase the antimicrobial effect of pharmaceutical compositions that can be applied to the skin

Country Status (10)

Country Link
EP (1) EP1214094A1 (en)
JP (1) JP2003509474A (en)
CN (1) CN1374874A (en)
AR (1) AR025713A1 (en)
AU (1) AU7363700A (en)
BR (1) BR0014117A (en)
CA (1) CA2391976A1 (en)
PL (1) PL354365A1 (en)
TR (1) TR200200724T2 (en)
WO (1) WO2001021209A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444710B1 (en) 1998-10-27 2002-09-03 Alcon Manufacturing, Ltd. Use of certain fatty acid/amino acid soaps to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions
TWI231759B (en) 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
FR2837710B1 (en) * 2002-03-26 2005-07-08 Innovations Pharma Ag TOPICAL COMPOSITION BASED ON ION-EXCHANGE RESINS, IN PARTICULAR FOR THE TREATMENT OF ERYTHEMES
US10918618B2 (en) * 2005-03-10 2021-02-16 3M Innovative Properties Company Methods of reducing microbial contamination
CN103079595B (en) * 2010-08-27 2015-11-25 若素制药株式会社 Eye drip use compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4209722C3 (en) * 1992-03-25 1997-06-19 Medproject Pharma Entwicklungs Dripable gel for ophthalmology
US5520920A (en) * 1992-08-28 1996-05-28 Alcon Laboratories, Inc. Use of certain anionic surfactants to enhance antimicrobial effectiveness of ophthalmic compositions
US5504113A (en) * 1994-03-02 1996-04-02 Allergan, Inc. Enhancement of benzalkonium chloride preservative activity in formulations containing an incompatible drug
JPH0977725A (en) * 1995-09-13 1997-03-25 Ajinomoto Co Inc Production of lysine salt of fatty acid
US6284749B1 (en) * 1998-10-27 2001-09-04 Alcon Manufacturing, Ltd. Preservative system for topically administrable pharmaceutical compositions containing a fatty acid/amino acid soap

Also Published As

Publication number Publication date
JP2003509474A (en) 2003-03-11
WO2001021209A1 (en) 2001-03-29
AR025713A1 (en) 2002-12-11
BR0014117A (en) 2002-05-14
EP1214094A1 (en) 2002-06-19
AU7363700A (en) 2001-04-24
PL354365A1 (en) 2004-01-12
CA2391976A1 (en) 2001-03-29
CN1374874A (en) 2002-10-16

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