TR200100056T2 - Nörotrofik faktörler - Google Patents
Nörotrofik faktörlerInfo
- Publication number
- TR200100056T2 TR200100056T2 TR2001/00056T TR200100056T TR200100056T2 TR 200100056 T2 TR200100056 T2 TR 200100056T2 TR 2001/00056 T TR2001/00056 T TR 2001/00056T TR 200100056 T TR200100056 T TR 200100056T TR 200100056 T2 TR200100056 T2 TR 200100056T2
- Authority
- TR
- Turkey
- Prior art keywords
- neurotrophic factors
- neublastin polypeptides
- antilcomas
- adhere
- construction
- Prior art date
Links
- 108010025020 Nerve Growth Factor Proteins 0.000 title 1
- 102000007072 Nerve Growth Factors Human genes 0.000 title 1
- 239000003900 neurotrophic factor Substances 0.000 title 1
- 102100026376 Artemin Human genes 0.000 abstract 2
- 238000010276 construction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
Abstract
Bulus, özellikle neublastin polipeptidlere yapisan neublastin neurotrofik faktör polipeptidleri neublastin polipeptidlerini kodlayan nükleik asitler ve antilkorlarla ve bunlarin yapim ve kullanim yöntemleriyle ilgilidir.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199800904 | 1998-07-06 | ||
US9222998P | 1998-07-09 | 1998-07-09 | |
DKPA199801048 | 1998-08-19 | ||
US9777498P | 1998-08-25 | 1998-08-25 | |
DKPA199801265 | 1998-10-06 | ||
US10390898P | 1998-10-13 | 1998-10-13 | |
US09/347,613 US6593133B1 (en) | 1998-07-06 | 1999-07-02 | Neurotrophic factors |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200100056T2 true TR200100056T2 (tr) | 2001-11-21 |
Family
ID=27561795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/00056T TR200100056T2 (tr) | 1998-07-06 | 1999-07-05 | Nörotrofik faktörler |
Country Status (18)
Country | Link |
---|---|
US (6) | US6593133B1 (tr) |
EP (2) | EP2290079A3 (tr) |
JP (5) | JP2002519061A (tr) |
KR (1) | KR100743376B1 (tr) |
AT (1) | ATE522609T1 (tr) |
AU (1) | AU755114B2 (tr) |
CA (1) | CA2336218C (tr) |
CY (1) | CY1112101T1 (tr) |
DK (1) | DK1095140T3 (tr) |
EE (1) | EE05590B1 (tr) |
ES (1) | ES2373173T3 (tr) |
HU (1) | HU227870B1 (tr) |
IS (1) | IS2835B (tr) |
NZ (1) | NZ508994A (tr) |
PT (1) | PT1095140E (tr) |
SI (1) | SI1095140T1 (tr) |
TR (1) | TR200100056T2 (tr) |
WO (1) | WO2000001815A2 (tr) |
Families Citing this family (38)
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US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
US20020055467A1 (en) * | 1998-07-06 | 2002-05-09 | Johansen Teit E. | Novel neurotrophic factors |
US7067473B1 (en) * | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
EP1097167B2 (en) * | 1998-07-14 | 2018-12-12 | Janssen Pharmaceutica NV | Neurotrophic growth factor |
US20020002269A1 (en) * | 1998-09-29 | 2002-01-03 | Jeffrey D. Milbrandt | Artemin, a neurotrophic factor |
JP2002531128A (ja) * | 1998-12-09 | 2002-09-24 | アムジエン・インコーポレーテツド | 神経栄養因子grnf4 |
US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
JP2002539176A (ja) * | 1999-03-15 | 2002-11-19 | カイロン コーポレイション | 眼の疾患を処置または予防するための組換え遺伝子送達ベクターの使用 |
EP1820860A3 (en) * | 1999-06-02 | 2008-03-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
AU2002232785B2 (en) * | 2000-12-22 | 2006-05-18 | Genentech, Inc. | Use of artemin, a member of the GDNF ligand family for preparing a neuroprotective medicament |
AR035077A1 (es) * | 2001-02-01 | 2004-04-14 | Biogen Inc | Polipeptidos de neublastina variante, proteinas de fusion, acidos nucleicos, vectores, celulas hospedadoras, metodos para producir dichos polipeptidos, dimeros, conjugados, composiciones farmaceuticas y uso de dichos polipeptidos en la preparacion de medicamentos |
US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
EP1395279B1 (en) * | 2001-03-28 | 2011-10-05 | Biogen Idec MA Inc. | Use of neublastin polypeptides for treating neuropathic pain |
US20040077543A1 (en) * | 2001-03-28 | 2004-04-22 | Sah Dinah W. Y. | Treatment using neublastin polypeptides |
AU2003249013A1 (en) * | 2002-07-09 | 2004-01-23 | Bristol-Myers Squibb Company | Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, bgs42 |
JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | 潤滑油組成物 |
GEP20115137B (en) * | 2003-01-31 | 2011-01-10 | Biogen Idec Inc | Method for induction folding of denaturated polypeptide neublastin |
NZ574121A (en) * | 2003-04-18 | 2011-06-30 | Biogen Idec Inc | Polyethylene glycol-conjugated gylcosylated neublastin and uses thereof for treatment of pain |
ES2323066T3 (es) | 2003-06-10 | 2009-07-06 | Nsgene A/S | Secrecion mejorada de neublastina. |
US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
CN1897977A (zh) * | 2003-10-20 | 2007-01-17 | Ns基因公司 | 帕金森氏病的体内基因治疗 |
EP1784203B1 (en) | 2004-08-19 | 2010-06-30 | Biogen Idec MA Inc. | Refolding transforming growth factor beta family proteins |
JP4852545B2 (ja) * | 2004-08-19 | 2012-01-11 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | ニューブラスチン(Neublastin)変異体 |
AU2006281798A1 (en) | 2005-08-16 | 2007-02-22 | Copenhagen University | GDNF derived peptides |
WO2007042040A2 (en) * | 2005-10-11 | 2007-04-19 | Ns Gene A/S | TREATMENT OF RETINOPATHIES USING GFRα3 AGONISTS |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
EP1993590B1 (en) * | 2006-03-01 | 2013-12-25 | Biogen Idec MA Inc. | Compostions and methods for administering gdnf ligand family proteins |
TWI445544B (zh) | 2007-05-01 | 2014-07-21 | Biogen Idec Inc | 增進血管形成之組合物及方法 |
EP2164870B1 (en) * | 2007-06-27 | 2015-12-09 | National University of Singapore | Polypeptides and polynucleotides for artemin and related ligands, and methods of use thereof |
EP2205634A2 (en) * | 2007-08-08 | 2010-07-14 | Biogen Idec MA, Inc. | Anti-neublastin antibodies and uses thereof |
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WO2014152511A1 (en) | 2013-03-15 | 2014-09-25 | The Jackson Laboratory | Methods for promoting wound healing and hair growth |
AU2014337504B2 (en) | 2013-10-14 | 2020-01-30 | Indiana University Research And Technology Corporation | Use of acamprosate to modulate ERK 1-2 activation in animal models for FXS and ASD and individuals diagnosed with FXS and ASD |
KR102288849B1 (ko) | 2014-03-17 | 2021-08-12 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 원추세포에서 증강된 유전자 발현을 위한 조성물 및 방법 |
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1999
- 1999-07-02 US US09/347,613 patent/US6593133B1/en not_active Expired - Lifetime
- 1999-07-05 PT PT99931023T patent/PT1095140E/pt unknown
- 1999-07-05 KR KR1020017000184A patent/KR100743376B1/ko not_active Expired - Fee Related
- 1999-07-05 SI SI9931062T patent/SI1095140T1/sl unknown
- 1999-07-05 EP EP10181304A patent/EP2290079A3/en not_active Withdrawn
- 1999-07-05 ES ES99931023T patent/ES2373173T3/es not_active Expired - Lifetime
- 1999-07-05 DK DK99931023.8T patent/DK1095140T3/da active
- 1999-07-05 CA CA2336218A patent/CA2336218C/en not_active Expired - Fee Related
- 1999-07-05 WO PCT/DK1999/000384 patent/WO2000001815A2/en active IP Right Grant
- 1999-07-05 NZ NZ508994A patent/NZ508994A/en not_active IP Right Cessation
- 1999-07-05 AU AU47693/99A patent/AU755114B2/en not_active Ceased
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- 1999-07-05 EP EP99931023A patent/EP1095140B1/en not_active Expired - Lifetime
- 1999-07-05 TR TR2001/00056T patent/TR200100056T2/tr unknown
- 1999-07-05 EE EEP200100008A patent/EE05590B1/xx not_active IP Right Cessation
- 1999-07-05 JP JP2000558205A patent/JP2002519061A/ja active Pending
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2000
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- 2000-12-14 IS IS5769A patent/IS2835B/is unknown
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2004
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2005
- 2005-06-01 JP JP2005161155A patent/JP2005341968A/ja not_active Withdrawn
- 2005-11-10 JP JP2005326745A patent/JP2006122053A/ja not_active Withdrawn
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2007
- 2007-04-27 JP JP2007120282A patent/JP2007252381A/ja not_active Withdrawn
- 2007-10-31 US US11/932,744 patent/US20080227703A1/en not_active Abandoned
- 2007-11-28 JP JP2007307603A patent/JP2008133282A/ja active Pending
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2009
- 2009-10-27 US US12/606,602 patent/US20100234293A1/en not_active Abandoned
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2011
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