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TR200002761T2 - HIV enfeksiyonlarının tedavisi için üç-ikameli 1,3,5-triazin türevleri. - Google Patents

HIV enfeksiyonlarının tedavisi için üç-ikameli 1,3,5-triazin türevleri.

Info

Publication number
TR200002761T2
TR200002761T2 TR2000/02761T TR200002761T TR200002761T2 TR 200002761 T2 TR200002761 T2 TR 200002761T2 TR 2000/02761 T TR2000/02761 T TR 2000/02761T TR 200002761 T TR200002761 T TR 200002761T TR 200002761 T2 TR200002761 T2 TR 200002761T2
Authority
TR
Turkey
Prior art keywords
compounds
treatment
substituted
triazine derivatives
hiv infections
Prior art date
Application number
TR2000/02761T
Other languages
English (en)
Inventor
Frans Desire Daeyaert Frederik
De Corte Bart
Rene De Jonge Marc
Heeres Jan
Yung Ho Chin
Adriaan Jan Janssen Paul
W.Kavash Robert
Maria Henricus Koymans Lucien
Joseph Kukla Michael
William Ludovici Donald
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of TR200002761T2 publication Critical patent/TR200002761T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C07D251/50—Two nitrogen atoms with a halogen atom attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/66—Derivatives of melamine in which a hetero atom is directly attached to a nitrogen atom of melamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Bu bulus, (I) formülün bilesikleri, bu bilesiklerin N-oksitleri, farmasötik açidan kabul edilebilir ilave tuzlari ve stereokimyasal açidan izomerik biçimlerinin HIV (Insan Bagisiklik-eksikligi Virüsü) enfeksiyonundan musdarip sujelerin tedavisi için bir tibbi maddenin imalati için kullanimina iliskindir. Bulus, bundan baska, (I) formülü bilesiklerinin bir alt-grubu olan yeni bilesiklere, bu bilesiklerin hazirlanmasi ve bu bilesikleri içeren farmasötik bilesimlere iliskindir.
TR2000/02761T 1998-03-27 1999-03-24 HIV enfeksiyonlarının tedavisi için üç-ikameli 1,3,5-triazin türevleri. TR200002761T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7963398P 1998-03-27 1998-03-27
EP98201589A EP0945447A1 (en) 1998-03-27 1998-05-14 Trisubstituted 1,3,5-triazine derivatives for treatment of HIV infections

Publications (1)

Publication Number Publication Date
TR200002761T2 true TR200002761T2 (tr) 2001-01-22

Family

ID=22151790

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02761T TR200002761T2 (tr) 1998-03-27 1999-03-24 HIV enfeksiyonlarının tedavisi için üç-ikameli 1,3,5-triazin türevleri.

Country Status (33)

Country Link
US (3) US6150360A (tr)
EP (2) EP0945447A1 (tr)
JP (1) JP2002511390A (tr)
KR (1) KR100593396B1 (tr)
CN (1) CN1157386C (tr)
AP (1) AP1475A (tr)
AR (1) AR018169A1 (tr)
AT (1) ATE295355T1 (tr)
AU (1) AU758624C (tr)
BG (1) BG64903B1 (tr)
BR (1) BR9909197A (tr)
CA (1) CA2324921C (tr)
DE (1) DE69925256T2 (tr)
DK (1) DK1066269T3 (tr)
EA (1) EA004540B1 (tr)
EE (1) EE200000535A (tr)
ES (1) ES2243056T3 (tr)
HK (1) HK1032394A1 (tr)
HR (1) HRP20000621A2 (tr)
HU (1) HUP0101372A3 (tr)
ID (1) ID26043A (tr)
IL (1) IL138670A (tr)
NO (1) NO317425B1 (tr)
NZ (1) NZ506787A (tr)
OA (1) OA11493A (tr)
PL (1) PL194660B1 (tr)
PT (1) PT1066269E (tr)
SI (1) SI1066269T1 (tr)
SK (1) SK14052000A3 (tr)
TR (1) TR200002761T2 (tr)
TW (1) TW570917B (tr)
WO (1) WO1999050256A1 (tr)
ZA (1) ZA200006042B (tr)

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CN1826328A (zh) * 2003-07-22 2006-08-30 神经能质公司 经取代的吡啶－2－基胺类似物
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CA2575002C (en) * 2004-08-10 2015-01-20 Janssen Pharmaceutica N.V. Hiv inhibiting 1,2,4-triazin-6-one derivatives
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Also Published As

Publication number Publication date
NO20004809L (no) 2000-11-24
EP1066269A1 (en) 2001-01-10
US6774235B2 (en) 2004-08-10
EA200000993A1 (ru) 2001-04-23
HRP20000621A2 (en) 2001-04-30
PL343195A1 (en) 2001-07-30
TW570917B (en) 2004-01-11
HUP0101372A3 (en) 2003-02-28
CN1295566A (zh) 2001-05-16
AU3599799A (en) 1999-10-18
EP1066269B1 (en) 2005-05-11
HK1032394A1 (en) 2001-07-20
CN1157386C (zh) 2004-07-14
ZA200006042B (en) 2001-10-26
AU758624C (en) 2004-03-11
JP2002511390A (ja) 2002-04-16
PL194660B1 (pl) 2007-06-29
OA11493A (en) 2004-05-07
SK14052000A3 (sk) 2001-06-11
BR9909197A (pt) 2000-12-05
AP2000001913A0 (en) 2000-09-30
NO20004809D0 (no) 2000-09-26
HUP0101372A2 (hu) 2001-10-28
EA004540B1 (ru) 2004-06-24
US6150360A (en) 2000-11-21
AU758624B2 (en) 2003-03-27
KR100593396B1 (ko) 2006-06-28
NO317425B1 (no) 2004-10-25
SI1066269T1 (en) 2005-10-31
ES2243056T3 (es) 2005-11-16
ID26043A (id) 2000-11-16
AR018169A1 (es) 2001-10-31
US20020115668A1 (en) 2002-08-22
EP0945447A1 (en) 1999-09-29
BG64903B1 (bg) 2006-08-31
DK1066269T3 (da) 2005-09-05
ATE295355T1 (de) 2005-05-15
KR20010034270A (ko) 2001-04-25
CA2324921A1 (en) 1999-10-07
WO1999050256A1 (en) 1999-10-07
EE200000535A (et) 2002-04-15
IL138670A (en) 2005-12-18
DE69925256D1 (de) 2005-06-16
NZ506787A (en) 2003-02-28
DE69925256T2 (de) 2006-02-23
PT1066269E (pt) 2005-09-30
AP1475A (en) 2005-10-03
US6372729B1 (en) 2002-04-16
CA2324921C (en) 2009-05-12
BG104716A (en) 2001-04-30

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